71 results about "Phytochemical" patented technology

Disclosed are novel pharmaceutical, animal feed compositions and methods of treating non-human animals comprising at least one component selected from the extract(s), fraction(s), active compound(s) and phytochemical(s), or mixtures thereof, derived from non-woody plants of the genus Hesperaloe. Animal feed compositions may comprise a basal animal feed and water soluble solids extracted from Hesperaloe and comprising at least one saponin. The water soluble solids may comprise from about 5 to about 30 wt % saponin. The compositions of the present invention can be used for the treatment of non-human animals, such as poultry and more particularly for preventing and treating coccidiosis. An embodiment provides an immunological composition useful for inducing the production of antibodies to an antigen in a non-human animal comprising an antigen, preferably a coccidia, and a saponin composition extracted from Hesperaloe. The saponins extracted from Hesperaloe biomass may comprise 25(27)-dehydrofucreastatin, 5(6),25(27)-disdehydroyuccaloiside C, 5(6)-disdehydroyuccaloiside C, furcreastatin and yuccaloiside C.

Disclosed is a novel quercetin-hexahydric alcohol cocrystal. These cocrystals have been developed as innovative pharmaceutical formulations. The present invention encompasses methods for producing these cocrystal materials, as well as their application as bioenhancers for active pharmaceutical ingredients, phytochemicals, vitamins, and minerals. The disclosed process for preparing quercetin-hexahydric alcohol cocrystals involves the formation of the cocrystal through a kinetic-controlled co crystallization process, enhancing the bioavailability and efficacy of bioactive compounds.

The invention belongs to the field of food processing and safety, and provides a steam explosion improved grain processing byproduct and application thereof in preparation of low-GI coarse grain biscuits. The triticale bran is pretreated through a steam explosion (SE) technology, the content of soluble dietary fibers is increased by 53.63% under the conditions of 1.0 MPa and 90 s, and the content of free phytochemicals and the oxidation resistance are the highest; the color of the wheat bran is changed into dark brown / dark brown from light brown, the interior of the wheat bran is of a porous honeycomb structure, the water binding capacity and the swelling property are improved, and an infrared spectrum shows that methyl and methylene structures are damaged and tissues are loosened; the fatty acid value is remarkably reduced, the storage period and the shelf life are effectively prolonged, comprehensive improvement of nutritional ingredients, physicochemical properties, biological activity and storage characteristics is achieved, and remarkable technical advantages are achieved.

The present invention relates to an albumin nanocomposite comprising a phytochemical, and a composition for improving muscle diseases comprising the same, and more specifically, to an albumin nanocomposite comprising a phytochemical, the present invention relates to an albumin nanocomposite containing phytochemicals, and more specifically, to an albumin nanocomposite containing phytochemicals, which exhibits the effects of inhibiting muscle reduction caused by oxidative stress or inflammatory response and promoting the differentiation of myoblasts into muscle cells. The albumin nanocomposite containing the phytochemicals can target and induce immune cells of active oxygen and inflammatory reaction and effectively deliver the phytochemicals, so that muscle cell atrophy is inhibited and differentiation is promoted by adjusting a muscle reduction signal mechanism induced by the active oxygen and the inflammatory reaction, and further muscle reduction can be improved, so that the curative effect of the albumin nanocomposite is improved. The muscular dystrophy is prevented and treated. Therefore, the composition containing the albumin nanocomposite containing phytochemicals of the present invention can be provided as a composition for improving muscle diseases.

The present invention provides a composition comprising adenosine or adenosine triphosphate (ATP) acting as an absorption enhancer when combined with a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug. Methods of administering ATP or adenosine to improve the bioavailability of a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug are described.

A light source for plant cultivation includes a first light source emitting a first type of light for photosynthesis of a plant and a second light source emitting a second type of light for adjustment of phytochemicals in the plant. The first type of light has at least one peak in the visible spectrum, and the second type of light has a peak in a different wavelength band from the first light source. The second type of light has a peak in the wavelength band of about 360 nm to about 420 nm.

A composition comprising Bidens pilosa or an active compound isolated from the Bidens pilosa for use in treating, inhibiting and / or decreasing the presence of pathogenic gut microbiota in an animal in need thereof is disclosed. The pathogenic gut microbiota are at least one selected from the group consisting of Brachyspira, porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis coronavirus (TGEV) and Rotavirus (RV). The composition is also for use in treating, inhibiting and / or decreasing occurrence of swine diarrhea, swine dysentery, swine viral infection and increasing the percentage of swine carcass and bone weight. In one embodiment, the composition is for use in treating, inhibiting and / or decreasing occurrence of swine dysentery associated with Brachyspira.

The invention relates to the technical field of food, in particular to rumex hanus and burdock green juice with multiple effects, and the rumex hanus and burdock green juice mainly comprises rumex hanus and burdock. The rumex hanus and the burdock are nutritional supplements based on plants, contain a large amount of protein, amino acid, vitamins, mineral substances and various plant compounds, and can achieve the effects of improving gastrointestinal digestion, resisting oxidation, reducing blood sugar and blood pressure and improving immunity.

Described are processes for the production of a composition comprising (2R, 3R, 4R, 5S)-3, 4, 5-trihydroxypiperidine-2-carboxylic acid (idoBR1), said process comprising the steps of: a) providing plant material from a botanical source comprising plant of the family Cucurbitaceae; b) fractionating said plant material to produce an extract enriched in idoBR1 c) assaying said extract for: i) inhibitory activity against sialidase or TNF-alpha or ii) IL-10 stimulatory activity; and d) formulating said assayed extract with a cosmetically-, nutraceutically- or pharmaceutically-acceptable excipient or carrier to produce a cosmetic, nutraceutical or pharmaceutical composition.

The present disclosure relates to an albumin nanocomposite comprising a phytochemical and a composition for muscle disease comprising the same, and more specifically, to an albumin nanocomposite comprising a phytochemical that exhibits an effect of inhibiting muscle loss caused by oxidative stress or inflammatory response and promoting the differentiation of myoblasts into muscle cells. The albumin nanocomposite comprising the phytochemical effectively delivers the phytochemical by targeting immune cells that induce reactive oxygen species and inflammatory responses. Accordingly, by regulating muscle-loss signaling pathways induced by reactive oxygen species and inflammatory responses, the nanocomposite inhibits muscle cell atrophy and promotes differentiation. Therefore, a composition comprising the albumin nanocomposite comprising the phytochemical according to the present disclosure can be provided as a composition for improving, preventing, or treating muscle diseases.

The invention discloses application of soyasaponin in preparation of a medicine for preventing and / or treating porcine reproductive and respiratory syndrome, and belongs to the technical field of biological function research of phytochemicals. In order to solve the technical problem that there is no medicine for effectively treating porcine reproductive and respiratory syndrome caused by PRRSV infection, the invention studies the inhibition effect of soyasaponin on PRRSV proliferation. The effect of inhibiting PRRSV proliferation can be achieved when the soybean saponin is administered during PRRSV infection, before PRRSV infection and after PRRSV infection, and the inhibition effect of the soybean saponin on the PRRSV proliferation has a time-dependent effect and a dose-dependent effect, so that the soybean saponin has the prospect of being developed into the medicine for resisting the porcine reproductive and respiratory syndrome virus.

The present invention relates to bioactive phytochemicals. Specifically, the present invention describes a method for producing a composition comprising (2R, 3R, 4R, 5S)-3, 4, 5-trihydroxypiperidine-2-carboxylic acid (idoBR1), the method comprising the steps of: (a) providing a plant material from a plant source including a plant of the family Cucurbitaceae; (b) fractionating the plant material to produce an extract rich in idoBR1 (idoBR1); (c) determining the following activities of the extract: (i) inhibitory activity against sialidase or TNF-alpha; or (ii) an IL-10 stimulating activity; and (d) formulating the assayed extract with a cosmetic, nutraceutical or pharmaceutically acceptable excipient or carrier to produce a cosmetic, nutraceutical or pharmaceutical composition.

Pharmaceutical formulations and methods to increase the bioactivity and bioavailability of plant compound having hydrophobic phytochemicals which have poor bioavailability due to poor water solubility. Dispersions of extracts of Boswellia and / or Curcuma longa in sesame seed oil. Analgesic and anti-inflammatory composition having a) an extract of Boswellia, b) one or more of an extract of Curcuma longa, a curcuminoid composition and combinations thereof, and, c) a sesame seed oil. The analgesic and anti-inflammatory composition has particles having a particle size ranging from less than about 20 micrometers to about 1 micrometer. The analgesic and anti-inflammatory composition provides a total combined specific surface area provided by particles in the composition ranging from about 900 meter2 per kilogram to about 3000 meter2 per kilogram of the composition. Methods of preparing the compositions and methods of treating inflammation and musculoskeletal disorders are provided.

The present invention relates to a phytochemical-containing albumin nanocomplex and a composition containing the same for improving muscle diseases. More specifically, the present invention relates to a phytochemical-containing albumin nanocomplex that has the effect of suppressing muscle loss caused by oxidative stress or inflammatory responses and promoting the differentiation of myoblasts into muscle cells. The phytochemical-containing albumin nanocomplex effectively delivers phytochemicals to immune cells that induce reactive oxygen species and inflammatory responses, thereby regulating the muscle loss signaling mechanism induced by reactive oxygen species and inflammatory responses, suppressing muscle cell atrophy, and promoting differentiation. This can improve muscle loss and prevent and treat muscle atrophy. Therefore, a composition containing the phytochemical-containing albumin nanocomplex of the present invention can be provided as a composition for improving muscle diseases.

A nanomaterial is gold or silver nanoparticle having a nanoparticle surface that consists of one or more of the following extracts from sweet gum leaves: shikimic acid, sweet gum leaf family of Catechins, sweet gum leaf family of Quercetin, Sweroside, Afzelechin, p-Coumaric Acid, Epiafzelechin Trimethyl Ether, Myricetin, Naringenin, Phloretin, Procyanidin B1 and related polyphenols, flavonoids and alkaloids. An antiviral / antibacterial agent includes sweet gum mediated silver nanoparticles having a core size and in a concentration having efficacy as an antiviral / antibacterial exceeding a 3 log 10 reduction in viral titer.

A cancer therapeutic agent includes a caffeic acid or cadambine phytochemicals cocktail on surfaces of gold nanoparticles. The agent can include a caffeic acid and cadambine phytochemicals cocktail on the surfaces of the gold nanoparticles. The surfaces are preferably stabilized with gum Arabic. The surfaces can consist of caffeic acid stabilized with gum Arabic, cadambine stabilized with gum Arabic, or caffeic acid and cadambine stabilized with gum Arabic. A method of forming the agents uses electrons of caffeic acid and / or cadambine to reduce gold salt(s) to gold nanoparticles without the use of any external toxic chemical reducing agents.

A non-fried fruit / vegetable-containing snack food product comprising a rigid starch matrix comprising potato starch and fruit and / or vegetables; and phytochemical(s) comprising a carotenoid, a glucosi

The invention relates to a skin care composition and method for treating partially sensitive skin, particularly in the vulval area. The skin care composition includes a hydrating mixture of liquid saturated hydrocarbons, a plant extract with anti-inflammatory phytochemicals, and water. The skin care composition is designed for aerosol dispensing. The invention also relates to a method that involves providing the composition and applying it to the sensitive skin area as an aerosol. The invention is not limited to vulval skin and can be used for other sensitive skin areas.

The present invention provides an isolated or engineered polypeptide, a microorganism comprising a nucleic acid sequence encoded by the polypeptide, and a method for synthesizing a polyphenolic phytochemicals phosphate derivative using the polypeptide or the microorganism. The polypeptide having a homologous protein sequence that is more than 70% identical to the polyphenol phosphorylation synthetase (SEQ ID NO: 13) comprises a conserved domain which sequentially comprises: an ATP-binding domain, which includes active catalytic sites of Lys27, Arg102, and Glu282; a substrate-binding domain, which includes a conserved motif of DDHHFYIDAMLDAKAR (SEQ ID NO: 14), and includes active catalytic sites of Asp627, His629, and His630; and a phosphorylated histidine catalytic domain, which includes His795 based on SEQ ID NO: 13.

The present invention relates to a pharmaceutical composition that combines psychedelic compounds, such as psilocybin, with one or more other component, such as fungi or plant or animal extracts and isolates, adaptogens, phytochemicals, algae, vitamins, minerals, amino acids, psychobiotics, or other such materials to improve user experience as compared to conventional psychedelics. A kit to modulate the effects of psychedelic compounds is also described. The present formulation is believed to have application in psychedelic-assisted therapy.

Described are compositions comprising selected isolated 4-hydroxymethyl-prolines, or pharmaceutically acceptable salts or derivatives thereof. Also described are novel 4-hydroxymethyl-N-methyl-prolines, together with processes for their preparation, compositions containing them, as well as their use as medicaments and pharmaceuticals. Also described are processes for producing a herbal medicine comprising the step of monitoring the quality of said herbal medicine by detecting the presence or absence or measuring the amount of one or more 4-hydroxymethyl-N-methyl-prolines in a sample of said herbal medicine.

A liquid composition for an electronic vaporization device, consisting essentially of an active inhalable source and a terpene source, is disclosed. A liquid composition for an electronic vaporization device is provided consisting essentially of greater than about 60 wt % cannabinoids, from about 5 to about 15 wt % terpenes and less than about 35 wt % non-cannabinoid, non-terpene cannabis phytochemicals. A method is provided for obtaining such a composition. An electronic vaping device and a cartridge for an electronic vaping device containing the composition are also disclosed.

The present invention discloses the phytochemicals extracted from plants as bio-pesticides and bio-stimulant, its composition and method of controlling various harmful organisms without being toxic to humans.

A phytochemical and nutraceutical composition and method for protection against a wide spectrum of viral and bacterial infections, including Covid-19, and for treatment of established infection and infectious inflammation. The composition includes a novel combination of vitamin, mineral, nutraceutical and phytochemical supplements. The composition of supplements and method may be compounded as a pill, tablet, powder, capsule or liquid be taken orally one or more times per day, and parenteral including nasal sprays and inhalers. Vitamin C and vitamin E along with zinc complexed with pyrithione or citrate are used in conjunction with nutraceuticals and phytochemicals provided, respectively, as immune boosters and antiviral agents along with anti-inflammatory nutraceuticals and phytochemicals.

A system for the synthesis of copper nanoparticles (CuNPs), comprising: a. a unit for the production of plant material configured to process leaves of Catharanthus roseus by washing, drying at 60°C, grinding to powder and boiling in distilled water to produce a plant extract; b. a unit for the preparation of a copper sulfate solution configured to dissolve copper sulfate pentahydrate (CuSO4-5H2O) in distilled water to obtain a solution of the desired molarity; c. a mixing unit configured to combine the plant extract with the copper sulfate solution in a specific ratio to initiate nanoparticle synthesis, facilitating the reduction of copper ions by phytochemicals in the plant extract; d. a purification unit configured to purify the synthesized copper nanoparticles by centrifugation; and e. an analysis unit, comprising: i. a UV-Vis spectrophotometer configured to confirm nanoparticle synthesis by detecting an absorption peak in the 250-300 nm range; ii. a Fourier-transform infrared spectrometer (FTIR) for identifying functional groups involved in nanoparticle synthesis; iii. a dynamic light scattering (DLS) device for measuring the particle size, size distribution and zeta potential of the nanoparticles.

The present invention provides a method of encapsulating a low solubility plant chemical in a water soluble nanocomposite. The method comprises providing a mixture comprising one or more proteins and a solvent, and adding an alkaline compound to adjust the pH of the mixture to an alkaline condition to unfold the three-dimensional structure of the protein. The zein and the low-solubility phytochemicals are sequentially added into the mixture, and it is worthy of noting that under the alkaline condition, the structure of the zein is expanded, and the phytochemicals are combined and fixed through hydrophobic interaction. And adjusting the pH value of the mixture to a neutral range by adding an acidic compound, so as to promote the protein to fold again and form a nano-composite solution. The nanocomplex solution is subsequently further dried to obtain a dried powder of a water-soluble nanocomplex wherein the particle size of the water-soluble nanocomplex is less than 1 micron, the structure of which is a protein-encapsulated low-solubility phytochemical.

Provided herein are genetically engineered mammalian cells that endogenously express one or more phytochemicals, vitamins or therapeutic agents and are suitable for culturing meat products. Methods of making and using the genetically engineered mammalian cells and the cultured meat products are also provided.

The invention belongs to the technical field of plant chemical component analysis, and discloses a multi-species polyphenol flavonoid compound high-throughput identification method which comprises the following steps: S1, constructing a cross-platform compatible MSP database; s2, sample pretreatment: carrying out ultrasonic extraction on a plant sample with 70% methanol, centrifuging, and filtering a supernatant with a filter membrane; wherein the plant sample comprises folium cortex eucommiae, rosemary, day lily, sea-buckthorn, herba houttuyniae or tea leaves; s3, carrying out liquid chromatography-mass spectrometry detection; s4, data matching and identification: using open source mass spectrum data processing software, setting the mass deviation to be less than or equal to 5ppm, the retention time deviation to be less than or equal to 0.3 min and the Dot product score to be more than or equal to 80%, and carrying out automatic identification; the technical problems that mass spectrum platform data is isolated, multi-species batch detection is difficult, the detection consistency is influenced by the matrix effect, and the compound identification efficiency is low are solved.

Disclosed here are compositions and methods for preventing or treating certain health conditions associated with inflammation or oxidative stress. These compositions are prepared from ingredients containing phytochemicals that activate the Nrf2 pathways. Synergistic effects of the different phytochemicals are also disclosed.