The invention belongs to the field of
plant chemistry, in particular to a method for extracting active molecule
alkaloid of
paper mulberry and application of the
alkaloid. The method comprises the following steps: taking roots or / and
bark or / and leaves as raw materials, and extracting the raw materials with water or water-containing alcoholic solution at normal temperature or
heating temperature; making the extracting solution pass strong acid type or weak acid type cation exchange resin, and adsorbing the
active components of the extracting solution on the resin; washing a resin column with water, eluting the resin column with
ammonia water / alcoholic solution, and concentrating and
drying the eluent to obtain the total
alkaloid of
paper mulberry; and concentrating the extracting solution, extracting the concentration solution with
ethyl acetate, alkalifying the water phase with alkali until the pH value is 12, extracting the water phase with n-butyl
alcohol, and concentrating the extracting solution of n-butyl
alcohol to obtain the total alkaloid of
paper mulberry. The alkaloid of paper mulberry prepared by the method can be directly used or added with edible auxiliary materials to prepare a medicament or
functional food capable of preventing diabetes and complications of the diabetes, or preventing
obesity, or treating viral influenza. The method also has the advantages of simple process, low cost and easy industrialization.