67 results about "Phytochemistry" patented technology

Disclosed are novel pharmaceutical, animal feed compositions and methods of treating non-human animals comprising at least one component selected from the extract(s), fraction(s), active compound(s) and phytochemical(s), or mixtures thereof, derived from non-woody plants of the genus Hesperaloe. Animal feed compositions may comprise a basal animal feed and water soluble solids extracted from Hesperaloe and comprising at least one saponin. The water soluble solids may comprise from about 5 to about 30 wt % saponin. The compositions of the present invention can be used for the treatment of non-human animals, such as poultry and more particularly for preventing and treating coccidiosis. An embodiment provides an immunological composition useful for inducing the production of antibodies to an antigen in a non-human animal comprising an antigen, preferably a coccidia, and a saponin composition extracted from Hesperaloe. The saponins extracted from Hesperaloe biomass may comprise 25(27)-dehydrofucreastatin, 5(6),25(27)-disdehydroyuccaloiside C, 5(6)-disdehydroyuccaloiside C, furcreastatin and yuccaloiside C.

The invention belongs to the field of food processing and safety, and provides a steam explosion improved grain processing byproduct and application thereof in preparation of low-GI coarse grain biscuits. The triticale bran is pretreated through a steam explosion (SE) technology, the content of soluble dietary fibers is increased by 53.63% under the conditions of 1.0 MPa and 90 s, and the content of free phytochemicals and the oxidation resistance are the highest; the color of the wheat bran is changed into dark brown / dark brown from light brown, the interior of the wheat bran is of a porous honeycomb structure, the water binding capacity and the swelling property are improved, and an infrared spectrum shows that methyl and methylene structures are damaged and tissues are loosened; the fatty acid value is remarkably reduced, the storage period and the shelf life are effectively prolonged, comprehensive improvement of nutritional ingredients, physicochemical properties, biological activity and storage characteristics is achieved, and remarkable technical advantages are achieved.

The present invention relates to an albumin nanocomposite comprising a phytochemical, and a composition for improving muscle diseases comprising the same, and more specifically, to an albumin nanocomposite comprising a phytochemical, the present invention relates to an albumin nanocomposite containing phytochemicals, and more specifically, to an albumin nanocomposite containing phytochemicals, which exhibits the effects of inhibiting muscle reduction caused by oxidative stress or inflammatory response and promoting the differentiation of myoblasts into muscle cells. The albumin nanocomposite containing the phytochemicals can target and induce immune cells of active oxygen and inflammatory reaction and effectively deliver the phytochemicals, so that muscle cell atrophy is inhibited and differentiation is promoted by adjusting a muscle reduction signal mechanism induced by the active oxygen and the inflammatory reaction, and further muscle reduction can be improved, so that the curative effect of the albumin nanocomposite is improved. The muscular dystrophy is prevented and treated. Therefore, the composition containing the albumin nanocomposite containing phytochemicals of the present invention can be provided as a composition for improving muscle diseases.

The present application relates to the field of plant physiology and ecology and plant chemistry, and particularly relates to a method for improving the content of gypenoside R2 in the root system of Suaeda by salt stress and application. The Suaeda plants are stressed by 100-300 mmol / L NaCl solution for 28 days, and the root system is collected to obtain the raw material rich in target saponins. The method can significantly improve the relative content of target saponins gypenoside R2 in the root system of Suaeda. Compared with the control group, the low-salt treatment can increase by 65.34%, the medium-salt treatment can increase by 161.83%, and the high-salt treatment can increase by 240.84%.

The application discloses application of an extract of Epiphyllum crenatum in preparation of a medicine for treating and improving intestinal diseases, relates to the fields of phytochemistry and microbiological technology, and the extract of the Epiphyllum crenatum is type I arabinogalactan. 6 The average molecular weight of the extract of the Epiphyllum crenatum extracted from petals of the Epiphyllum crenatum is 5.767*10 6 Da, and the backbone structure is a polysaccharide of β-Galp connected through (1→4) bonds, which expands the application potential of the Epiphyllum crenatum, improves the value of the Epiphyllum crenatum, and provides a new raw material for the field of the medicine for treating and improving intestinal diseases.

The invention belongs to the technical field of phytochemistry and medicines, and discloses a hemostatic active component from paris polyphylla Franch., an active ingredient, a composition and application of the hemostatic active component, the active ingredient and the composition. The active component mainly contains steroid saponin. The invention also relates to a compound with hemostatic activity, and the compound is 21-hydroxy polyphyllin VII. The active component, the active ingredient and the hemostatic active compound provided by the invention are obtained by extracting a paris polyphylla plant material. Experiments show that the active component and the active ingredient of the paris polyphylla pall have a remarkable hemostatic effect and can be used as a medicine for treating hemorrhagic diseases.

A composition comprising Bidens pilosa or an active compound isolated from the Bidens pilosa for use in treating, inhibiting and / or decreasing the presence of pathogenic gut microbiota in an animal in need thereof is disclosed. The pathogenic gut microbiota are at least one selected from the group consisting of Brachyspira, porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis coronavirus (TGEV) and Rotavirus (RV). The composition is also for use in treating, inhibiting and / or decreasing occurrence of swine diarrhea, swine dysentery, swine viral infection and increasing the percentage of swine carcass and bone weight. In one embodiment, the composition is for use in treating, inhibiting and / or decreasing occurrence of swine dysentery associated with Brachyspira.

An organic sol-gel nano-composition containing three solid lipid nano-components loaded with phytochemical active ingredients is proposed. Panax notoginseng saponins are extracted from Vietnamese Panax notoginseng. Rutin is extracted from Styphnolobium japonicum in Thai Binh Province, Vietnam, and Ginkgo biloba is extracted from Ginkgo biloba trees. The composition has shown to have low toxicity and great bioavailability. In particular, the composition is effective against local myocardial ischemias and arrhythmias, improves the blood rheology, platelet circulation and antiaggregation, and thrombosis, lowers the blood lipids to a certain limit, and has good effects against atherosclerosis. The composition has an antioxidant effect of preventing free radical damages, and has an effect of enhancing capillary resistance, strengthening the vessel walls that reduces hypertension risks, which accordingly protects the cerebral nerves, prevents strokes, and is also used to recover after strokes and other hemorrhagic diseases for the enhancement effects and reconstruction of the damaged blood vessels.

Smart Automated Medicinal Plant Extraction and Phytochemical Analysis Device

The plant chemical type rapid collection device and collection method provided by the application, wherein the plant chemical type rapid collection device comprises a mounting seat, a pull rod and a sampling needle wrapped with stainless steel fibers, the pull rod is coaxially connected with the sampling needle and is arranged in the axial direction of the mounting seat, a sealing sleeve is arranged on the side end face of the mounting seat facing the sampling needle, and the sampling needle can be accommodated in the sealing sleeve; the stainless steel fibers are provided with a silica resin-PMSQ microsphere coating. The plant chemical type rapid collection device and collection method provided by the application adopt a new type of polymethylsilsesquioxane microsphere coating, so that the plant chemical type rapid collection device, especially the sampling needle, has the characteristics of high temperature resistance, good acid and alkali resistance and high extraction efficiency, and can fully absorb plant tissue components in a short time; the plant chemical type rapid collection device is designed and manufactured with a sealing sleeve, and can temporarily store plant samples for a long time.

Water dispersible phyto-extract and / or phytochemical compound compositions suitable for the preparation of beverages, in particular beverages containing one or more phyto-extracts and / or phytochemical compounds, beverage concentrates and methods of preparing same.

The application relates to the technical field of plant chemistry and active ingredient heterocyclic compounds of traditional Chinese medicine, and discloses a C17 sesquiterpene alkaloid, a preparation method and application, wherein the C17 sesquiterpene alkaloid and a pharmaceutically acceptable salt thereof are shown as formula I; the C17 sesquiterpene alkaloid of formula I is separated from an ethanol extract n-butanol extraction phase of Dendrobium huoshanense stems through three-step operations of silica gel column chromatography, acid solution and base precipitation and recrystallization; the structure of the compound is determined through nuclear magnetic resonance, high-resolution mass spectrometry and single crystal diffraction analysis; experiments show that the C17 sesquiterpene alkaloid can effectively inhibit the survival and proliferation of A549 lung cancer cells, has good anti-lung cancer activity, and can be used for preparing anti-lung cancer drugs.

The present disclosure relates to an albumin nanocomposite comprising a phytochemical and a composition for muscle disease comprising the same, and more specifically, to an albumin nanocomposite comprising a phytochemical that exhibits an effect of inhibiting muscle loss caused by oxidative stress or inflammatory response and promoting the differentiation of myoblasts into muscle cells. The albumin nanocomposite comprising the phytochemical effectively delivers the phytochemical by targeting immune cells that induce reactive oxygen species and inflammatory responses. Accordingly, by regulating muscle-loss signaling pathways induced by reactive oxygen species and inflammatory responses, the nanocomposite inhibits muscle cell atrophy and promotes differentiation. Therefore, a composition comprising the albumin nanocomposite comprising the phytochemical according to the present disclosure can be provided as a composition for improving, preventing, or treating muscle diseases.

The invention provides a lignan compound in phyllanthus emblica and application of the lignan compound in preparation of cosmetics and medicines, and belongs to the technical field of medicines. Five lignan compounds Phyllanthus emblica A-E, namely phyllanthus emblica A-E, are obtained from Phyllanthus emblica L. leaves, a thin layer chromatography method is mainly adopted for guidance, a high performance liquid chromatography separation technology and other plant chemical research means are combined, and a DPPH free radical scavenging activity evaluation model and an LPS-induced NO inhibition model are adopted, so that the phyllanthus emblica A-E can be used for preparing the phyllanthus emblica L. extract, and the phyllanthus emblica L. extract can be used for preparing the phyllanthus emblica L. extract, the phyllanthus emblica L. extract, the phyllanthus emblica L. extract and the phyllanthus emblica L. extract and the phyllanthus emblica L. extract. The traditional Chinese medicine composition is prepared into a solid, liquid or paste dosage form according to a conventional method, so that the anti-oxidation and anti-inflammatory treatment effects are realized. The lignan compound disclosed by the invention is simple and convenient in preparation method, high in yield and excellent in purity, and the obtained compound is a new natural secondary metabolite and has remarkable antioxidant and anti-inflammatory activity.

The present invention discloses a nutritional composition and method of using and making the nutritional composition. The nutritional composition is a hydrolyzed pea protein based nutrient composition for use in both enteral and oral feeding, and provides a non-allergenic diet for providing optimal nutrition to users. The nutritional composition is made from organic and plant-based ingredients. The nutritional composition has pea protein hydrolysates, phytochemical extracts, fatty acids, organic ingredients free of the top eight allergens and corn, and prebiotic fiber. The nutritional composition is provided in liquid form for enteral and / or oral feeding.

The invention relates to the field of plant physiological ecology and phytochemistry research, in particular to a method for increasing flavonoid substances in suaeda salsa root exudates under saline-alkali stress and application. And carrying out stress treatment on the suaeda salsa plant for 6-8 weeks by using a NaCl solution with the concentration of 50-300 mmol / L or an alkali solution with the pH value of 8.0-9.0, and collecting a culture solution to obtain the root exudates rich in target flavonoid substances. According to the method, the relative content of the target flavonoid substance 3, 5-Di-O-methyl-8-prenylafelectin-4beta-ol in the suaeda salsa root exudates can be remarkably increased, and compared with a control group, the relative content of the target flavonoid substance 3, 5-Di-O-methyl-8-prenylafelectin-4beta-ol in the suaeda salsa root exudates can be increased by 44.64% through low-salt (100 mmol / L NaCl) treatment and can be increased by 28.9% through high-alkali (pH 9.0) treatment.

The present invention relates to a phytochemical-containing albumin nanocomplex and a composition containing the same for improving muscle diseases. More specifically, the present invention relates to a phytochemical-containing albumin nanocomplex that has the effect of suppressing muscle loss caused by oxidative stress or inflammatory responses and promoting the differentiation of myoblasts into muscle cells. The phytochemical-containing albumin nanocomplex effectively delivers phytochemicals to immune cells that induce reactive oxygen species and inflammatory responses, thereby regulating the muscle loss signaling mechanism induced by reactive oxygen species and inflammatory responses, suppressing muscle cell atrophy, and promoting differentiation. This can improve muscle loss and prevent and treat muscle atrophy. Therefore, a composition containing the phytochemical-containing albumin nanocomplex of the present invention can be provided as a composition for improving muscle diseases.

The application discloses a separation and purification preparation method of high-purity gleditsia saponin monomer, and relates to the technical field of phytochemistry. The method comprises the following steps: obtaining gleditsia sinensis raw material powder; adding the gleditsia sinensis raw material powder into an ethanol solution, adjusting pH, performing ultrasonic extraction, collecting supernatant after centrifugation, repeatedly extracting residues, combining the extraction solutions, and obtaining gleditsia sinensis saponin crude extract; adding a flocculating agent into the crude extract, stirring, sedimentation, suction filtration, filtering through an ultrafiltration membrane, and collecting permeate; loading the permeate into a macroporous adsorption resin column, gradient elution, collecting target eluent, vacuum concentration, and obtaining gleditsia sinensis saponin crude product; gradient elution of the gleditsia sinensis saponin crude product through a silica gel column, collecting components containing gleditsioside A, high-performance liquid chromatography refining, and obtaining gleditsioside A product; dissolving the gleditsioside A product in a mixed solvent, dissolving, cooling, standing crystallization, suction filtration, washing, and obtaining a crystal; vacuum drying the crystal, and obtaining high-purity gleditsia sinensis saponin monomer gleditsioside A.

The application discloses a sesquiterpene compound in llex spicata and an extraction and separation method and application thereof, relates to the technical field of plant chemical extraction and separation, and provides a sesquiterpene compound in llex spicata, which is characterized by comprising at least one of llex spicata lactone F, llex spicata lactone G and llex spicata lactone H. The application provides an extraction method of the sesquiterpene compound in llex spicata, and the three sesquiterpenes obtained by the extraction and separation method are all new compounds which have not been reported. The llex spicata sesquiterpene compound has antibacterial and anti-inflammatory activities, and has potential development value for diseases such as fungal infection, pharyngitis and pneumonia. The llex spicata sesquiterpene compound also has the effects of skin damage repair and anti-aging, and can be applied to the field of cosmetics.

A cancer therapeutic agent includes a caffeic acid or cadambine phytochemicals cocktail on surfaces of gold nanoparticles. The agent can include a caffeic acid and cadambine phytochemicals cocktail on the surfaces of the gold nanoparticles. The surfaces are preferably stabilized with gum Arabic. The surfaces can consist of caffeic acid stabilized with gum Arabic, cadambine stabilized with gum Arabic, or caffeic acid and cadambine stabilized with gum Arabic. A method of forming the agents uses electrons of caffeic acid and / or cadambine to reduce gold salt(s) to gold nanoparticles without the use of any external toxic chemical reducing agents.

MODULAR LABORATORY APPARATUS FOR PHYTOCHEMICAL EXTRACTION, BIOASSAY AND PHARMACEUTICAL FORMULATION

The invention belongs to the field of natural product chemistry and phytochemistry, and particularly relates to application of salvia miltiorrhiza crude polysaccharide, salvia miltiorrhiza oligosaccharide or salvia miltiorrhiza polysaccharide to identification of salvia miltiorrhiza from different producing areas. The production places of different salvia miltiorrhiza bunge are judged according to the different saccharide fragments, the molecular weights of SMP and SMO, monosaccharide components and the proportion of the monosaccharide components, and subsequent research on the salvia miltiorrhiza bunge saccharide structure and function is facilitated. The adopted identification method is simple and easy to operate, low in cost and beneficial to being widely used in production. Meanwhile, in-depth study is carried out on different sugar fragments of salvia miltiorrhiza crude polysaccharides from different producing areas and monosaccharide components and structures of SMO and SMP, and the structure of sugar has a certain influence on the physiological function of the salvia miltiorrhiza, so that a foundation is laid for subsequent study of the salvia miltiorrhiza.

The present invention discloses the phytochemicals extracted from plants as bio-pesticides and bio-stimulant, its composition and method of controlling various harmful organisms without being toxic to humans.

A system for the environmentally friendly synthesis, adsorption testing and characterization of nickel oxide nanoparticles, comprising: a plant extract processing plant configured to extract a phytochemical-rich solution from gooseberry biomass by controlled Soxhlet reflux and continuous water circulation; a pre-reaction and mixing chamber which is operationally connected to the extract preparation unit and is configured to receive metered volumes of the extract and an aqueous nickel nitrate hexahydrate solution, the chamber comprising a temperature-controlled stirrer, a pH probe and a peristaltic feed pump to maintain the homogeneity of the solution and the pH within a predefined range; a microprocessor-controlled calcination and combustion unit connected downstream of the reaction chamber and configured to thermally decompose the reaction mixture into nickel oxide nanoparticles under programmed temperature cycles between 300 °C and 700 °C; a nanoparticle collector and drying system configured to separate, transport and dry the synthesized nanoparticles under inert air circulation at controlled temperature; an adsorption test module with two reaction chambers for simultaneous testing of the adsorption of amaranth dye and hexavalent chromium, each reaction chamber comprising an integrated UV-Vis probe, magnetic stirrer, heating plate and microvalve-controlled reagent inlets for pH modulation; a characterization interface configured to transmit optical and surface data from the nanoparticles via dedicated optical and mechanical coupling ports to analytical instruments such as UV-Vis spectrophotometers, FTIR spectrometers, XRD analyzers, and SEM imaging systems; and a central control and processing unit consisting of a microcontroller configured to receive sensor data from temperature, pH and optical transducers, execute synthesis and adsorption control techniques, calculate adsorption kinetics and output real-time process parameters as well as adsorption efficiency.

The invention belongs to the technical field of phytochemistry, and particularly discloses a calbistrin compound with antifungal activity as well as a preparation method and application of the calbistrin compound. The compound disclosed by the invention is prepared from a fermentation crude extract of a strain of tobacco endophytic fungus Aspergillus japonicus TE-739D, and the compound disclosed by the invention is prepared from the fermentation crude extract of the tobacco endophytic fungus Aspergillus japonicus TE-739D. The compounds have been subjected to detailed structural identification by modern spectroscopy techniques, such as high resolution mass spectrometry HRESIMS and superconductive nuclear magnetic resonance spectroscopy NMR. Through SciFindern database retrieval, the compound is found to be a compound with a new structure, and the compound is named as Japonidiene G. The Calbistrin compound Japonidiene G has strong inhibitory activity on various plant pathogenic fungi, the activity of the Calbistrin compound Japonidiene G on alternaria alternata and phytophthora capsici is superior to that of a positive drug carbendazim, and the activity of the Calbistrin compound Japonidiene G on botrytis cinerea is equivalent to that of the positive drug carbendazim.

A phytochemical and nutraceutical composition and method for protection against a wide spectrum of viral and bacterial infections, including Covid-19, and for treatment of established infection and infectious inflammation. The composition includes a novel combination of vitamin, mineral, nutraceutical and phytochemical supplements. The composition of supplements and method may be compounded as a pill, tablet, powder, capsule or liquid be taken orally one or more times per day, and parenteral including nasal sprays and inhalers. Vitamin C and vitamin E along with zinc complexed with pyrithione or citrate are used in conjunction with nutraceuticals and phytochemicals provided, respectively, as immune boosters and antiviral agents along with anti-inflammatory nutraceuticals and phytochemicals.

The present invention discloses synergistic herbal compositions comprising combination of a first ingredient selected from Centella asiatica extract containing at least one component selected from magnesium salt or complex of asiatic acid and magnesium salt or complex of madecassic acid or mixtures thereof along with asiaticoside and madecassoside; and a second ingredient selected from extract, fraction, phytochemical or mixtures thereof derived from Theobroma cacao; process for their preparation, methods of treatment and use of such nootropic compositions for improving cognitive functions or mental abilities and gaming performance.

The present invention provides a method of encapsulating a low solubility plant chemical in a water soluble nanocomposite. The method comprises providing a mixture comprising one or more proteins and a solvent, and adding an alkaline compound to adjust the pH of the mixture to an alkaline condition to unfold the three-dimensional structure of the protein. The zein and the low-solubility phytochemicals are sequentially added into the mixture, and it is worthy of noting that under the alkaline condition, the structure of the zein is expanded, and the phytochemicals are combined and fixed through hydrophobic interaction. And adjusting the pH value of the mixture to a neutral range by adding an acidic compound, so as to promote the protein to fold again and form a nano-composite solution. The nanocomplex solution is subsequently further dried to obtain a dried powder of a water-soluble nanocomplex wherein the particle size of the water-soluble nanocomplex is less than 1 micron, the structure of which is a protein-encapsulated low-solubility phytochemical.

The present invention relates to a composition effective in treating diabetes and dyslipidemia prepared according to the solid lipid nanotechnology from two natural phytochemical active ingredients: cinnamonaldehyde extracted from the Vietnamese cinnamon and berberine as a bioactive compound extracted from several plants, including a group of shrubs called Berberis. Via testing, all of the composition of the present invention has shown to have low toxicity and great bioavailability, reduced insulin resistance that allows the sugar level in blood to more effectively induce reduction of insulin, hyperglycolysis that aids the body in cellular sugar decomposition, reduced sugar production in the liver, carbohydrate decomposition slowed down in the intestines, and an increasing in the number of beneficial microbes in the intestines. The composition is effective in reducing the total cholesterol level (TC), and non-HDL-cholesterol, and has a tendency to reduce TG level.

Disclosed here are compositions and methods for preventing or treating certain health conditions associated with inflammation or oxidative stress. These compositions are prepared from ingredients containing phytochemicals that activate the Nrf2 pathways. Synergistic effects of the different phytochemicals are also disclosed.