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113 results about "Phytochemistry" patented technology

'Phytochemistry is the study of phytochemicals, which are chemicals derived from plants. Those studying phytochemistry strive to describe the structures of the large number of secondary metabolic compounds found in plants, the functions of these compounds in human and plant biology, and the biosynthesis of these compounds. Plants synthesize phytochemicals for many reasons, including to protect themselves against insect attacks and plant diseases. Phytochemicals in food plants are often active in human biology, and in many cases have health benefits. The compounds found in plants are of many kinds, but most are in four major biochemical classes, the alkaloids, glycosides, polyphenols, and terpenes.

Intelligent analysis method for spatial-temporal variation of stoichiometric characteristics of forest plants

The invention relates to the technical field of ecological environment monitoring and forest remote sensing, in particular to a forest plant stoichiometric characteristic spatial-temporal change intelligent analysis method, which comprises the following steps: S1, acquiring spectral reflectivity and element concentration values of plant leaves in a target area; s2, performing space-time registration processing; s3, constructing a three-dimensional space-time matrix, and generating a space-time cube with a dynamic weight identifier; s4, calculating the space-time gradient variation of the carbon-nitrogen-phosphorus ratio in each space unit; s5, performing feature decoupling on the space-time gradient variation; and S6, generating a stoichiometric characteristic three-dimensional atlas with altitude-time double coordinate axes. According to the method, by constructing the multi-factor driven three-dimensional space-time analysis model, decoupling analysis of long-term trend and short-term fluctuation of forest plant stoichiometric characteristics is achieved, the element flux mutation threshold value at the terrain turning position is accurately recognized, and the dynamic monitoring capacity of the ecological process is effectively improved.
Owner:GUIZHOU ACAD OF FORESTRY SCI

Saponin containing extracts prepared from Hesperaloe useful in the treatment of non-human animals

Disclosed are novel pharmaceutical, animal feed compositions and methods of treating non-human animals comprising at least one component selected from the extract(s), fraction(s), active compound(s) and phytochemical(s), or mixtures thereof, derived from non-woody plants of the genus Hesperaloe. Animal feed compositions may comprise a basal animal feed and water soluble solids extracted from Hesperaloe and comprising at least one saponin. The water soluble solids may comprise from about 5 to about 30 wt % saponin. The compositions of the present invention can be used for the treatment of non-human animals, such as poultry and more particularly for preventing and treating coccidiosis. An embodiment provides an immunological composition useful for inducing the production of antibodies to an antigen in a non-human animal comprising an antigen, preferably a coccidia, and a saponin composition extracted from Hesperaloe. The saponins extracted from Hesperaloe biomass may comprise 25(27)-dehydrofucreastatin, 5(6),25(27)-disdehydroyuccaloiside C, 5(6)-disdehydroyuccaloiside C, furcreastatin and yuccaloiside C.
Owner:KIMBERLY CLARK WORLDWIDE INC

Hippophae rhamnoides fruit water-soluble micromolecule and component extraction process thereof

The invention discloses a sea buckthorn fruit water-soluble micromolecule and a component extraction process thereof, and relates to the technical field of natural plant chemistry. The method comprises the following steps: S1, pretreating the sea buckthorn fruits, namely crushing the sea buckthorn fruits, accurately weighing the crushed sea buckthorn fruits, adding ultrapure water according to a ratio of 1g: 10mL, carrying out hot water extraction and centrifugation, and filtering impurities by using a filter membrane; s2, extracting sea buckthorn fruit water-soluble small molecules, adding high-concentration absolute ethyl alcohol into centrifugally filtered supernate, sealing and standing overnight at 4 DEG C, centrifuging an alcohol precipitation sample, filtering, performing vacuum evaporation by using a rotary evaporator to remove ethyl alcohol and water, weighing, re-supplementing ultrapure water, heating in a water bath for dissolving, and filtering to obtain the sea buckthorn fruit water-soluble small molecules. Finally, filtering to obtain a sea buckthorn fruit water-soluble micromolecule extracting solution, and refrigerating and storing at 4 DEG C; according to the method, the water-soluble micromolecular chemical components of the sea buckthorn fruits are extracted by using a water extraction and high-concentration ethanol precipitation technology for the first time; the functional analysis shows that the water-soluble small molecule extract has antibacterial biological activity.
Owner:TIBET UNIV

Steam explosion improved grain processing by-product and application of steam explosion improved grain processing by-product in preparation of low-GI coarse grain biscuits

The invention belongs to the field of food processing and safety, and provides a steam explosion improved grain processing byproduct and application thereof in preparation of low-GI coarse grain biscuits. The triticale bran is pretreated through a steam explosion (SE) technology, the content of soluble dietary fibers is increased by 53.63% under the conditions of 1.0 MPa and 90 s, and the content of free phytochemicals and the oxidation resistance are the highest; the color of the wheat bran is changed into dark brown / dark brown from light brown, the interior of the wheat bran is of a porous honeycomb structure, the water binding capacity and the swelling property are improved, and an infrared spectrum shows that methyl and methylene structures are damaged and tissues are loosened; the fatty acid value is remarkably reduced, the storage period and the shelf life are effectively prolonged, comprehensive improvement of nutritional ingredients, physicochemical properties, biological activity and storage characteristics is achieved, and remarkable technical advantages are achieved.
Owner:SHANDONG ACADEMY OF AGRICULTURAL SCIENCES

Preparation method and application of monoterpene Trichodesmic acid

The invention discloses a preparation method and application of monoterpene Trichodesmic acid, and relates to the technical field of medicines and phytochemistry, the structural formula of the Trichodesmic acid is # imgabs0 #, and the molecular formula of the Trichodesmic acid is C10H16O5; the invention relates to application of Trichodesmic acid in prevention and treatment of meloidogyne incognita. Trichodesmic acid is separated from janapan seeds, and the compound has relatively strong nematicidal activity on meloidogyne incognita.
Owner:YUNNAN FENGMANG BIOTECHNOLOGY CO LTD +2

Benzo [e] pyrrolo [1, 2-a] aza compound as well as preparation method and application thereof

The invention belongs to the technical field of phytochemistry, and particularly relates to a benzo [e] pyrrolo [1, 2-a] aza # imgabs0 # compound as well as a preparation method and application thereof. The preparation method comprises the following steps: fermenting cigar stem barks, drying the fermented cigar stem barks in the sun, crushing and sieving to obtain a material a; adding a first solvent into the material a for reflux extraction to obtain an extracting solution, concentrating the extracting solution, adding a second solvent for extraction, combining the extracted extraction phases, and performing vacuum concentration to obtain an extract b; carrying out silica gel column chromatography on the extract b, eluting with chloroform-acetone eluent, monitoring by TLC (Thin Layer Chromatography), and collecting the eluent; and purifying the eluent by using a sephadex column, and separating and purifying by using high performance liquid chromatography to obtain the benzo [e] pyrrolo [1, 2-a] aza # imgabs 1 # compound with tobacco black shank resisting activity. The compound is novel in structure, has relatively good black shank resistance activity, can be used as a lead compound for resisting tobacco black shank, and is used for research and development of biological pesticides for preventing and treating tobacco black shank.
Owner:YUNNAN ACAD OF TOBACCO AGRI SCI +1

Application of 4,15-diacetylverrucarol in herbicides

The present invention belongs to the technical field of phytochemistry, and particularly relates to the application of 4,15-diacetylverrucarol in herbicides. The present invention discovers the herbicidal activity of the sesquiterpenoid compound 4,15-diacetylverrucarol against the main gramineous weeds in the field, and has the potential to be developed into a natural green biological selective herbicide.
Owner:SANYA INSTITUTE OF NANJING AGRICULTURAL UNIVERSITY +1

Albumin nanocomposites comprising phytochemicals and compositions for improving muscle diseases comprising same

The present invention relates to an albumin nanocomposite comprising a phytochemical, and a composition for improving muscle diseases comprising the same, and more specifically, to an albumin nanocomposite comprising a phytochemical, the present invention relates to an albumin nanocomposite containing phytochemicals, and more specifically, to an albumin nanocomposite containing phytochemicals, which exhibits the effects of inhibiting muscle reduction caused by oxidative stress or inflammatory response and promoting the differentiation of myoblasts into muscle cells. The albumin nanocomposite containing the phytochemicals can target and induce immune cells of active oxygen and inflammatory reaction and effectively deliver the phytochemicals, so that muscle cell atrophy is inhibited and differentiation is promoted by adjusting a muscle reduction signal mechanism induced by the active oxygen and the inflammatory reaction, and further muscle reduction can be improved, so that the curative effect of the albumin nanocomposite is improved. The muscular dystrophy is prevented and treated. Therefore, the composition containing the albumin nanocomposite containing phytochemicals of the present invention can be provided as a composition for improving muscle diseases.
Owner:SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Method for improving content of notoginseng saponin R2 in rhizome of suaeda by salt stress and application thereof

PendingCN122439703APhytochemistryPlantlet
The present application relates to the field of plant physiology and ecology and plant chemistry, and particularly relates to a method for improving the content of gypenoside R2 in the root system of Suaeda by salt stress and application. The Suaeda plants are stressed by 100-300 mmol / L NaCl solution for 28 days, and the root system is collected to obtain the raw material rich in target saponins. The method can significantly improve the relative content of target saponins gypenoside R2 in the root system of Suaeda. Compared with the control group, the low-salt treatment can increase by 65.34%, the medium-salt treatment can increase by 161.83%, and the high-salt treatment can increase by 240.84%.
Owner:SHIJIAZHUANG INST OF AGRI MODERNIZATION CHINESE ACAD OF SCI

Application of Epiphyllum extract in the preparation of drugs for treating / improving intestinal diseases

The application discloses application of an extract of Epiphyllum crenatum in preparation of a medicine for treating and improving intestinal diseases, relates to the fields of phytochemistry and microbiological technology, and the extract of the Epiphyllum crenatum is type I arabinogalactan. 6 The average molecular weight of the extract of the Epiphyllum crenatum extracted from petals of the Epiphyllum crenatum is 5.767*10 6 Da, and the backbone structure is a polysaccharide of β-Galp connected through (1→4) bonds, which expands the application potential of the Epiphyllum crenatum, improves the value of the Epiphyllum crenatum, and provides a new raw material for the field of the medicine for treating and improving intestinal diseases.
Owner:SICHUAN UNIV

Hemostatic active component, active component and composition of ball medicine paris polyphylla and application of hemostatic active component and composition

The invention belongs to the technical field of phytochemistry and medicines, and discloses a hemostatic active component from paris polyphylla Franch., an active ingredient, a composition and application of the hemostatic active component, the active ingredient and the composition. The active component mainly contains steroid saponin. The invention also relates to a compound with hemostatic activity, and the compound is 21-hydroxy polyphyllin VII. The active component, the active ingredient and the hemostatic active compound provided by the invention are obtained by extracting a paris polyphylla plant material. Experiments show that the active component and the active ingredient of the paris polyphylla pall have a remarkable hemostatic effect and can be used as a medicine for treating hemorrhagic diseases.
Owner:KUNMING INST OF BOTANY CHINESE ACAD OF SCI

Light source for plant cultivation and method of plant cultivation using thereof

A light source for plant cultivation includes a first light source emitting a first type of light for photosynthesis of a plant and a second light source emitting a second type of light for adjustment of phytochemicals in the plant. The first type of light has at least one peak in the visible spectrum, and the second type of light has a peak in a different wavelength band from the first light source. The second type of light has a peak in the wavelength band of about 360 nm to about 420 nm.
Owner:CHUNGBUK NAT UNIV IND ACADEMIC COOP FOUNDATION +1

Bidens pilosa and its phytochemicals for use in prevention and treatment of diarrhea

A composition comprising Bidens pilosa or an active compound isolated from the Bidens pilosa for use in treating, inhibiting and / or decreasing the presence of pathogenic gut microbiota in an animal in need thereof is disclosed. The pathogenic gut microbiota are at least one selected from the group consisting of Brachyspira, porcine epidemic diarrhea virus (PEDV), transmissible gastroenteritis coronavirus (TGEV) and Rotavirus (RV). The composition is also for use in treating, inhibiting and / or decreasing occurrence of swine diarrhea, swine dysentery, swine viral infection and increasing the percentage of swine carcass and bone weight. In one embodiment, the composition is for use in treating, inhibiting and / or decreasing occurrence of swine dysentery associated with Brachyspira.
Owner:ACAD SINICA

Organic sol-gel nano-composition from panax notoginseng, rutin, ginkgo biloba effective in enhancing cerebral and cardiovascular protection and method of producing thereof

ActiveUS12440527B2Organic active ingredientsNervous disorderDiseaseCapillary Resistance
An organic sol-gel nano-composition containing three solid lipid nano-components loaded with phytochemical active ingredients is proposed. Panax notoginseng saponins are extracted from Vietnamese Panax notoginseng. Rutin is extracted from Styphnolobium japonicum in Thai Binh Province, Vietnam, and Ginkgo biloba is extracted from Ginkgo biloba trees. The composition has shown to have low toxicity and great bioavailability. In particular, the composition is effective against local myocardial ischemias and arrhythmias, improves the blood rheology, platelet circulation and antiaggregation, and thrombosis, lowers the blood lipids to a certain limit, and has good effects against atherosclerosis. The composition has an antioxidant effect of preventing free radical damages, and has an effect of enhancing capillary resistance, strengthening the vessel walls that reduces hypertension risks, which accordingly protects the cerebral nerves, prevents strokes, and is also used to recover after strokes and other hemorrhagic diseases for the enhancement effects and reconstruction of the damaged blood vessels.
Owner:VAN NGUYEN ANH

Ferric oxide nanoparticles for wastewater disinfection

A method of making a ferric oxide (Fe2O3) nanoparticle (NP) composition including providing Rosa rugosa cv. plena (RP) extract; adding the RP extract to a solution of FeCl3 to obtain RP-Fe3Cl4; and activating phytochemical compounds in the RP extract to obtain a phyto-synthesized RP-Fe2O3 NP composition.
Owner:KING FAISAL UNIV

C-23 spirocholestane type steroid compound as well as preparation method and application thereof

The invention belongs to the technical field of phytochemistry and botanical pesticides, and relates to a C-23 spiro cholestane type steroid compound as well as a preparation method and application thereof. The C-23 spiro-cholestane type steroid compound disclosed by the invention has a remarkable inhibition effect on growth of grass, and can be used as an effective component of a plant source herbicide.
Owner:KUNMING INST OF BOTANY CHINESE ACAD OF SCI

Phytochemical rapid collection device and collection method

The plant chemical type rapid collection device and collection method provided by the application, wherein the plant chemical type rapid collection device comprises a mounting seat, a pull rod and a sampling needle wrapped with stainless steel fibers, the pull rod is coaxially connected with the sampling needle and is arranged in the axial direction of the mounting seat, a sealing sleeve is arranged on the side end face of the mounting seat facing the sampling needle, and the sampling needle can be accommodated in the sealing sleeve; the stainless steel fibers are provided with a silica resin-PMSQ microsphere coating. The plant chemical type rapid collection device and collection method provided by the application adopt a new type of polymethylsilsesquioxane microsphere coating, so that the plant chemical type rapid collection device, especially the sampling needle, has the characteristics of high temperature resistance, good acid and alkali resistance and high extraction efficiency, and can fully absorb plant tissue components in a short time; the plant chemical type rapid collection device is designed and manufactured with a sealing sleeve, and can temporarily store plant samples for a long time.
Owner:HUBEI NORMAL UNIV

High-efficiency extraction and conversion method of oligomeric proanthocyanidins and its application

The invention relates to the technical field of plant chemistry, and in particular to an efficient extraction and conversion method for oligomeric proanthocyanidins and an application thereof. The method comprises mixing a proanthocyanidin polymer and a low eutectic solvent, eluting the mixed solution through resin adsorption, and drying the eluate to obtain the oligomeric proanthocyanidins. Compared with the prior art, the conversion method of the invention is novel, simple and fast, and realizes one-pot conversion. The obtained proanthocyanidin extraction rate is higher than that of most traditional ethanol and methanol proanthocyanidins. The obtained proanthocyanidins have an average polymerization degree of 3.19, which is oligomeric proanthocyanidins and is lower than the polymerization degree of most traditional ethanol and methanol proanthocyanidins. The obtained oligomeric proanthocyanidins have important significance for product development in other fields such as the medical field, the cosmetic field, and the food industry field.
Owner:NINGBO RONGYUANCHUN TRADING CO LTD

Methods for improving agronomic traits of a plant

Methods for improving one or more agronomic traits of a plant by selecting a plant variety that exhibits overcompensation is provided as is a method for producing one or more plant products from a modified plant that exhibits improvements in one or more agronomic traits. The methods may include reducing or inhibiting the biosynthetic production of one or more plant chemical defense compounds prior to removing the plant apical meristem at a time that is known to cause overcompensation in selected plants.
Owner:THE BOARD OF TRUSTEES OF THE UNIV OF ILLINOIS

Water Dispersible Botanical Compositions

Water dispersible phyto-extract and / or phytochemical compound compositions suitable for the preparation of beverages, in particular beverages containing one or more phyto-extracts and / or phytochemical compounds, beverage concentrates and methods of preparing same.
Owner:AQUILA BLACK LTD

Intelligent analysis method for spatiotemporal changes in stoichiometric characteristics of forest plants

The present invention relates to the fields of ecological environment monitoring and forest remote sensing technology, and specifically to an intelligent analysis method for the spatiotemporal variation of forest plant stoichiometric characteristics. The method comprises the following steps: S1: obtaining the spectral reflectance and element concentration values of plant leaves in a target area; S2: performing spatiotemporal registration processing; S3: constructing a three-dimensional spatiotemporal matrix to generate a spatiotemporal cube with dynamic weight identifiers; S4: calculating the spatiotemporal gradient variation of the carbon, nitrogen, and phosphorus ratio within each spatial unit; S5: performing feature decoupling on the spatiotemporal gradient variation; and S6: generating a three-dimensional map of stoichiometric characteristics with dual altitude-time coordinate axes. By constructing a multi-factor-driven three-dimensional spatiotemporal analysis model, the present invention achieves decoupling analysis of long-term trends and short-term fluctuations in forest plant stoichiometric characteristics, accurately identifying element flux mutation thresholds at topographic turning points, and effectively enhancing the dynamic monitoring capabilities of ecological processes.
Owner:GUIZHOU ACAD OF FORESTRY SCI

A c17 sesquiterpene alkaloid, methods of preparation and uses

The application relates to the technical field of plant chemistry and active ingredient heterocyclic compounds of traditional Chinese medicine, and discloses a C17 sesquiterpene alkaloid, a preparation method and application, wherein the C17 sesquiterpene alkaloid and a pharmaceutically acceptable salt thereof are shown as formula I; the C17 sesquiterpene alkaloid of formula I is separated from an ethanol extract n-butanol extraction phase of Dendrobium huoshanense stems through three-step operations of silica gel column chromatography, acid solution and base precipitation and recrystallization; the structure of the compound is determined through nuclear magnetic resonance, high-resolution mass spectrometry and single crystal diffraction analysis; experiments show that the C17 sesquiterpene alkaloid can effectively inhibit the survival and proliferation of A549 lung cancer cells, has good anti-lung cancer activity, and can be used for preparing anti-lung cancer drugs.
Owner:WEST ANHUI UNIV

Albumin nanocomposite comprising phytochemical and composition for improving muscle disease containing same

The present disclosure relates to an albumin nanocomposite comprising a phytochemical and a composition for muscle disease comprising the same, and more specifically, to an albumin nanocomposite comprising a phytochemical that exhibits an effect of inhibiting muscle loss caused by oxidative stress or inflammatory response and promoting the differentiation of myoblasts into muscle cells. The albumin nanocomposite comprising the phytochemical effectively delivers the phytochemical by targeting immune cells that induce reactive oxygen species and inflammatory responses. Accordingly, by regulating muscle-loss signaling pathways induced by reactive oxygen species and inflammatory responses, the nanocomposite inhibits muscle cell atrophy and promotes differentiation. Therefore, a composition comprising the albumin nanocomposite comprising the phytochemical according to the present disclosure can be provided as a composition for improving, preventing, or treating muscle diseases.
Owner:SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

Lignan compound in phyllanthus emblica and application thereof

The invention provides a lignan compound in phyllanthus emblica and application of the lignan compound in preparation of cosmetics and medicines, and belongs to the technical field of medicines. Five lignan compounds Phyllanthus emblica A-E, namely phyllanthus emblica A-E, are obtained from Phyllanthus emblica L. leaves, a thin layer chromatography method is mainly adopted for guidance, a high performance liquid chromatography separation technology and other plant chemical research means are combined, and a DPPH free radical scavenging activity evaluation model and an LPS-induced NO inhibition model are adopted, so that the phyllanthus emblica A-E can be used for preparing the phyllanthus emblica L. extract, and the phyllanthus emblica L. extract can be used for preparing the phyllanthus emblica L. extract, the phyllanthus emblica L. extract, the phyllanthus emblica L. extract and the phyllanthus emblica L. extract and the phyllanthus emblica L. extract. The traditional Chinese medicine composition is prepared into a solid, liquid or paste dosage form according to a conventional method, so that the anti-oxidation and anti-inflammatory treatment effects are realized. The lignan compound disclosed by the invention is simple and convenient in preparation method, high in yield and excellent in purity, and the obtained compound is a new natural secondary metabolite and has remarkable antioxidant and anti-inflammatory activity.
Owner:KUNMING INST OF BOTANY CHINESE ACAD OF SCI

Application of soyasaponin in preparation of medicine for preventing and / or treating porcine reproductive and respiratory syndrome

The invention discloses application of soyasaponin in preparation of a medicine for preventing and / or treating porcine reproductive and respiratory syndrome, and belongs to the technical field of biological function research of phytochemicals. In order to solve the technical problem that there is no medicine for effectively treating porcine reproductive and respiratory syndrome caused by PRRSV infection, the invention studies the inhibition effect of soyasaponin on PRRSV proliferation. The effect of inhibiting PRRSV proliferation can be achieved when the soybean saponin is administered during PRRSV infection, before PRRSV infection and after PRRSV infection, and the inhibition effect of the soybean saponin on the PRRSV proliferation has a time-dependent effect and a dose-dependent effect, so that the soybean saponin has the prospect of being developed into the medicine for resisting the porcine reproductive and respiratory syndrome virus.
Owner:HARBIN VETERINARY RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES (CHINA ANIMAL HEALTH & EPIDEMIOLOGY CENTER HARBIN BRANCH CENTER)

Hydrolyzed pea protein-based nutrient composition

The present invention discloses a nutritional composition and method of using and making the nutritional composition. The nutritional composition is a hydrolyzed pea protein based nutrient composition for use in both enteral and oral feeding, and provides a non-allergenic diet for providing optimal nutrition to users. The nutritional composition is made from organic and plant-based ingredients. The nutritional composition has pea protein hydrolysates, phytochemical extracts, fatty acids, organic ingredients free of the top eight allergens and corn, and prebiotic fiber. The nutritional composition is provided in liquid form for enteral and / or oral feeding.
Owner:KATE FARMS INC

Method for increasing flavonoid substances in suaeda salsa root exudates under saline-alkali stress and application

The invention relates to the field of plant physiological ecology and phytochemistry research, in particular to a method for increasing flavonoid substances in suaeda salsa root exudates under saline-alkali stress and application. And carrying out stress treatment on the suaeda salsa plant for 6-8 weeks by using a NaCl solution with the concentration of 50-300 mmol / L or an alkali solution with the pH value of 8.0-9.0, and collecting a culture solution to obtain the root exudates rich in target flavonoid substances. According to the method, the relative content of the target flavonoid substance 3, 5-Di-O-methyl-8-prenylafelectin-4beta-ol in the suaeda salsa root exudates can be remarkably increased, and compared with a control group, the relative content of the target flavonoid substance 3, 5-Di-O-methyl-8-prenylafelectin-4beta-ol in the suaeda salsa root exudates can be increased by 44.64% through low-salt (100 mmol / L NaCl) treatment and can be increased by 28.9% through high-alkali (pH 9.0) treatment.
Owner:SHIJIAZHUANG INST OF AGRI MODERNIZATION CHINESE ACAD OF SCI

Albumin nanocomplex containing phytochemicals and composition containing the same for improving muscle diseases

The present invention relates to a phytochemical-containing albumin nanocomplex and a composition containing the same for improving muscle diseases. More specifically, the present invention relates to a phytochemical-containing albumin nanocomplex that has the effect of suppressing muscle loss caused by oxidative stress or inflammatory responses and promoting the differentiation of myoblasts into muscle cells. The phytochemical-containing albumin nanocomplex effectively delivers phytochemicals to immune cells that induce reactive oxygen species and inflammatory responses, thereby regulating the muscle loss signaling mechanism induced by reactive oxygen species and inflammatory responses, suppressing muscle cell atrophy, and promoting differentiation. This can improve muscle loss and prevent and treat muscle atrophy. Therefore, a composition containing the phytochemical-containing albumin nanocomplex of the present invention can be provided as a composition for improving muscle diseases.
Owner:SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION

A method for separating and purifying high-purity gleditsia saponin monomer

PendingCN122404463AFiltrationGradient elution
The application discloses a separation and purification preparation method of high-purity gleditsia saponin monomer, and relates to the technical field of phytochemistry. The method comprises the following steps: obtaining gleditsia sinensis raw material powder; adding the gleditsia sinensis raw material powder into an ethanol solution, adjusting pH, performing ultrasonic extraction, collecting supernatant after centrifugation, repeatedly extracting residues, combining the extraction solutions, and obtaining gleditsia sinensis saponin crude extract; adding a flocculating agent into the crude extract, stirring, sedimentation, suction filtration, filtering through an ultrafiltration membrane, and collecting permeate; loading the permeate into a macroporous adsorption resin column, gradient elution, collecting target eluent, vacuum concentration, and obtaining gleditsia sinensis saponin crude product; gradient elution of the gleditsia sinensis saponin crude product through a silica gel column, collecting components containing gleditsioside A, high-performance liquid chromatography refining, and obtaining gleditsioside A product; dissolving the gleditsioside A product in a mixed solvent, dissolving, cooling, standing crystallization, suction filtration, washing, and obtaining a crystal; vacuum drying the crystal, and obtaining high-purity gleditsia sinensis saponin monomer gleditsioside A.
Owner:HENANHANYIDAILYCHEMICALTECHNOLOGY CO LTD