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75 results about "Gastric digestion" patented technology

Gastric digestion. n. The part of digestion, chiefly of proteins, carried on in the stomach by the enzymes of the gastric juices.peptic digestion.

Device for simulating gastric digestion and using method of device

The invention discloses a device for simulating gastric digestion and a using method of the device. The device comprises a gastric reaction vessel, a stirrer, a water bath control system, a computer monitoring system, a gastric emptying pump and the like. The using method comprises the following steps: gastric juice and a solution / dispersion liquid of a substance to be tested are added to the gastric reaction vessel; the stirrer simulates gastric peristalsis; the water bath control system controls the temperature in the reaction vessel; the computer monitoring system monitors the temperature, pH and digestion time in the gastric reaction vessel; the gastric emptying constant-flow pump simulates gastric emptying; digested products are collected; the activity of pepsin is eliminated; the digestion simulation process is repeated for three times; the digestion condition of the substance to be tested is tested. According to the invention, the detailed gastric digestion process is simulated for the first time; gastric digestion conditions after various active or nutritious substances enter a human body can be observed and explored; the simulated environment is in accordance with the physiological environment of a human body; the fitness between the digestion in the simulated environment and the gastric digestion is high; accuracy of control over the environment simulation is high.
Owner:NANCHANG UNIV

Dynamic bionic mouse stomach digestive system device

The invention relates to a dynamic bionic mouse stomach digestive system device capable of being used for effective simulation of mixing, digesting and emptying of foods and medicines of different types and structures in the real mouse stomach. An external bionic mouse stomach silica gel model of the dynamic bionic mouse stomach digestive system device is used for storing, mixing, digesting and emptying of the foods. An external electric compression instrument vertically extrudes the external bionic mouse stomach silica gel model. A feeding-emptying device controls the secretion speed of the simulated gastric fluid into the external bionic mouse stomach silica gel model and the emptying speed of the chyme. An insulation box controls the temperature of a control box in the manner of heating the air in the insulation box. The external bionic mouse stomach silica gel model of the device is made of high-elasticity, high-stability and high-transparency addition type silicone rubber raw materials and has the form and size of the real mouse stomach and the details of the physiological structure. The device is easy to operate and convenient to wash, the comparison can be conveniently made with an internal live mouse experiment result, and the defects can be scientifically assessed and overcome.
Owner:NANTONG EAST CONCEPT NEW MATERIAL CO LTD

Experimental device for automatic simulation of gastrointestinal continuous digestion and application method

PendingCN110231437AStable pHReal-time monitoring of particle size changesMaterial analysisPylorusPh regulation
The invention provides a device capable of realizing automatic simulation of gastrointestinal continuous digestion and an application method of the device. The device comprises a stomach reactor, a stirrer, a constant-temperature water circulation system, a gastrointestinal fluid conveying system, a gastric emptying control device, an automatic pH titration device, a small intestine reactor and asample receiving device. According to the application method, to-be-digested food is conveyed into a stomach digester, stomach digestive fluid is input at a constant speed, the stirrer simulates stomach peristalsis, a micropore glass plate at the bottom of the stomach reactor simulates a pylorus to realize stomach "sieving emptying", the to-be-digested food is conveyed into a pH regulation chamberfor automatic pH regulation, small intestine digestion is simulated in the small intestine reactor provided with an internally-arranged latex sleeve, and the pressure-changing water circulation system is adopted to realize regular vibration of the latex sleeve so as to simulate the stomach peristalsis. Through the device and the application method, the whole reaction process can be continuous andautomatic under the situation that parameters are set; and moreover, the device is simple in structure, free of a complicated control system and easy to assemble and can be used to realize a digestion simulation experiment in a scientific research experiment.
Owner:HEFEI UNIV OF TECH

Heavy metal bioavailability testing device and method for simulating human gastric digestion characteristics

The invention discloses a heavy metal bioavailability testing device and method for simulating human gastric digestion characteristics. The testing device comprises a container for simulating gastricdigestion reaction; a gastric digestion reaction feed module connected with the container for simulating the gastric digestion reaction and used for supplementing liquid and gas required for simulating the human gastric digestion in the container, thereby simulating the human gastric juice secretion and anaerobic digestion environment; a stirring module located at the bottom of the container for simulating the gastric digestion reaction and used for stirring the liquid in the container, thereby simulating the peristole of the human stomach; a temperature control module connected with the container for simulating the gastric digestion reaction and used for controlling the temperature of the liquid in the container, thereby simulating the temperature environment of the human stomach; a monitoring module located in the container for simulating the gastric digestion reaction and used for monitoring the temperature and pH value of the liquid in the container; and a digestion reaction collection module communicating with the container for simulating the gastric digestion reaction, and used for simulating the gastric emptying and collecting the digested liquid in the container.
Owner:JIANGSU PROVINCIAL ACAD OF ENVIRONMENTAL SCI

Program-controlled pig bionic digestion system and method using program-controlled pig bionic digestion system to quickly determining digestible energy value of pig feed

The invention discloses a program-controlled pig bionic digestion system and a method using the program-controlled pig bionic digestion system to quickly determining a digestible energy value of pig feed. The method comprises the following steps that a feed sample is pulverized and sieved through a standard sieve; a gastric buffer solution and an intestinal buffer solution are prepared; simulatedgastric juice, simulated small intestinal juice and simulated large intestinal juice are prepared; the pulverized feed sample is filled into a simulated digester of the program-controlled pig bionic digestion system, and the simulated gastric juice is added in sequence through computer program control to simulate gastric digestion; after the intestinal buffer solution is added, the simulated smallintestinal juice is added to simulate small intestinal digestion; the simulated large intestinal juice is added to simulate large intestinal digestion; inactivation is carried out after the digestionis completed; and then cleaning is carried out, after undigested residues are obtained, a total energy value of the residues and the feed sample is tested, and the digestible energy value of the feedis calculated. The method is simple, high in precision, low in implementation cost, and the digestible energy value of the pig feed can be accurately determined within 72 hours.
Owner:INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI

Blueberry wine which is made by high-acid hawthorn and has gastric-digestion promoting function and preparing method

The invention discloses blueberry wine which is made by high-acid hawthorn and has the gastric-digestion promoting function. The blueberry wine is characterized by comprising, by weight, 100-120 parts of blueberries, 18-20 parts of high-acid hawthorn, 2-3 parts of pectinase, 3-5 parts of yeast cell walls, 3.4-4 parts of glucose, 1-2 parts of citric acid modified attapulgite, 6-8 parts of bean dreg submicron powder, 0.2-0.4 part of protease, 0.34-0.38 part of sodium thiosulfate, 5.5-6.1 parts of fruit wine brewing yeast, 4.8-6.8 parts of submicron zeolite powder and a proper amount of water. The blueberry health-care wine which is unique in taste and capable of promoting gastric digestion is prepared in the mode that the high-acid hawthorn and the blueberries are combined in proportion and fermented, high acid has the certain delay effect on the growth of yeast, fermentation time can be prolonged, the fermenting power of the yeast is improved through the high temperature and the yeast cell walls for improving the yeast activity in the different fermentation stages respectively, the fermentation time is prolonged, and enough time is provided for forming of fermentation intermediate products.
Owner:安徽味多多餐饮管理有限公司

Traditional Chinese medicine composition for assisting rehabilitation after chemoradiotherapy of cancer patients

The invention aims to overcome defects in the prior art and adverse reaction caused by western medicine after chemoradiotherapy of cancer patients, and provides a traditional Chinese medicine composition for assisting rehabilitation after the chemoradiotherapy of cancer patients. The traditional Chinese medicine composition is prepared by repeated verification of clinical tests, and conforms to the traditional Chinese medicine theory. According to the traditional Chinese medicine composition, hedyotis diffusa, Chinese actinidia root, cicca arietina, aspongopus and trigone are used as monarch drugs to resist cancer and inhibit tumor diffusion and deterioration; liriope spicata, rhizoma kaempferiae, Chinese hawthorn leaf, radix polygonati officinalis, rice sprout and hippophae rhamnoides are used as ministerial drugs to nourish yin, generate body fluid, promote qi, warm middle, promote gastric digestion and improve food intake; pepper, ginger, inula flower, cortex albiziae, lentinula edodes and black sesame are used as auxiliary drugs to warm middle, stop pain, calm nerves, relieve depression, activate blood and eliminate carbuncle; prepared rehmannia root, radix glycyrrhizae, carrot, mulberry, spina date seed and codonopsis pilosula are used as adjuvant drugs to improve immunity, nourish blood, nourish yin, reinforce essence, benefit marrow, strengthen middle and tonify qi.
Owner:王永顺

Integrated human gastrointestinal tract digestive absorption in-vitro substitution model

The invention provides an integrated human gastrointestinal tract digestive absorption in-vitro substitution model. 12 systems are integrated into an integrated in-vitro simulation digestive model. The systems include a stomach digestion simulation system, a small intestine digestion simulation system, a small intestine absorption simulation system, a large intestine decomposition simulation system, a central intelligent control system, a pH control system, a temperature control system, a stirring rate control system, a conveying system, a central purification system, an automatic cleaning anddisinfection system and an anaerobic system. Through the synergistic effect of the systems, the in-vitro substitution model not only simulates the digestive absorption process of gastrointestinal tracts in vitro, but also simulates the fermentation and decomposition process of intestinal microbial communities at the same time. The model is suitable for accurately quantifying the in-vivo metabolicprocess and toxic effect of nutrients or pollutants in a food matrix to obtain related data such as biological accessibility, biological effectiveness, metabolism trend and microorganism interactionof the nutrients or pollutants, and accurate risk assessment is realized.
Owner:SOUTHERN MEDICAL UNIVERSITY +1

An integrated in vitro surrogate model of human gastrointestinal digestion and absorption

The invention provides an integrated human gastrointestinal digestion and absorption in vitro substitution model, which is integrated by 12 systems into an integrated in vitro simulation digestion model, including a gastric digestion simulation system, a small intestine digestion simulation system, a small intestine absorption simulation system, a large intestine Decomposition simulation system, central intelligent control system, pH control system, temperature control system, stirring rate control system, conveying system, central purification system, automatic cleaning and disinfection system and anaerobic system. Through the synergy of various systems, this in vitro surrogate model not only simulates the digestion and absorption process of the gastrointestinal tract in vitro, but also simulates the fermentation and decomposition process of the intestinal microbial community. This model is suitable for accurately quantifying the metabolic process and toxic effect of nutrients or pollutants in the food matrix in the body, and obtaining relevant data such as bioaccessibility, bioavailability, metabolic fate and interaction with microorganisms of nutrients or pollutants. Realize precise risk assessment.
Owner:SOUTHERN MEDICAL UNIVERSITY +1

Method for preparing antioxidative peptide liquid of collagen gel with combination of ultrasonic treatment and simulative digestion

InactiveCN107338278AGood for enzymatic digestionSpeed ​​up the self-assembly processFermentationWater bathsGastric digestion
The invention discloses a method for preparing an antioxidative peptide liquid of collagen gel with combination of ultrasonic treatment and simulative digestion and belongs to the technical field of food processing technology and protein utilization. According to the adopted preparation process, the collagen gel is prepared from pepsin-soluble collagen taken as a raw material through dissolution, dialysis, ultrasonic treatment and self-assembly under a water bath, an in-vitro simulative gastrointestinal digestion technology is used, a bionic dynamic rat gastric digestion system capable of simulating peristole frequency and amplitude and simulating a secretory gland to secrete gastric digestive juice is used, then intestinal digestion is simulated, and two-step enzyme digestion is adopted by means of pepsin-trypsin. The enzyme degradation rate is increased greatly, and the rate of utilization of the raw material is increased. A dynamic model is used for simulating gastrointestinal digestion processes and is closer to a human body simulative digestion environment in an environment at 37 DEG C, the process is more efficient, and the method is safer and more reliable as compared with an artificial synthesis method and a fermentation method for antioxidative peptides.
Owner:JIANGSU UNIV
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