Dynamic bionic mouse stomach digestive system device

A digestive system, bionic mouse technology, applied in educational appliances, instruments, teaching models, etc., can solve the problems of high cost, complex structure, inconvenient disassembly and cleaning, etc., and achieve the effect of low cost, high stability and simple operation

Inactive Publication Date: 2015-03-25
NANTONG EAST CONCEPT NEW MATERIAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, none of them have the details of the shape and physiological structure of the real stomach (size, folds on the inner wall of the stomach, etc.), cannot reproduce the distribution of food in the real stomach and the sequence of digestion and emptying, and lack effective simulation of the peristalsis and contraction of the stomach wall
In addition, these systems are complex in structure, high in cost, and inconvenient to disassemble and clean; due to ethical restrictions, it is impossible to easily obtain physiological parameters related to the human gastrointestinal tract, which makes it impossible to effectively verify the validity and scientific nature of the above systems

Method used

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  • Dynamic bionic mouse stomach digestive system device
  • Dynamic bionic mouse stomach digestive system device
  • Dynamic bionic mouse stomach digestive system device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] use as Figure 6 The dynamic bionic mouse stomach digestive system device shown simulates the digestion and emptying process of casein powder in the mouse stomach, and detects the content of the digested product of casein powder - soluble polypeptide (expressed as the equivalent of tyrosine) To quantitatively describe the digestibility of casein powder. The experimental results were compared with the in vivo live mouse experiments to verify the effectiveness of the device. The specific operation process is as follows:

[0036] 1) Turn on the power of the spotlight and the switch of the digital display thermostat, start heating the air inside the insulation box, and automatically turn off the power switch of the spotlight when the temperature reaches 37°C.

[0037] 2) Connect one side of the silicone rubber tube (inner diameter: 3.0 mm, outer diameter: 5.0 mm) filled with simulated gastric juice (37°C) with Figure 6 connected to the single-channel syringe pump shown,...

Embodiment 2

[0046] use as image 3 The dynamic bionic mouse stomach digestion system device shown simulates the mixing and digestion process of raw rice grains in the stomach of rats, and the degree of digestion of rice grains is indicated by detecting the particle size distribution of rice grains and the concentration of maltose, the main digestion product of rice grains. The experimental results were compared with the experimental results of live mice in vivo to verify the effectiveness of the device. The specific operation process is as follows:

[0047] 1) Turn on the power of the spotlight and the switch of the digital display thermostat, start heating the air inside the insulation box, and automatically turn off the power switch of the spotlight when the temperature reaches 37°C.

[0048] 2) Connect one side of the silicone rubber tube (inner diameter: 3.0 mm, outer diameter: 5.0 mm) filled with simulated gastric juice (37°C) with Figure 6 connected to the single-channel syringe ...

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Abstract

The invention relates to a dynamic bionic mouse stomach digestive system device capable of being used for effective simulation of mixing, digesting and emptying of foods and medicines of different types and structures in the real mouse stomach. An external bionic mouse stomach silica gel model of the dynamic bionic mouse stomach digestive system device is used for storing, mixing, digesting and emptying of the foods. An external electric compression instrument vertically extrudes the external bionic mouse stomach silica gel model. A feeding-emptying device controls the secretion speed of the simulated gastric fluid into the external bionic mouse stomach silica gel model and the emptying speed of the chyme. An insulation box controls the temperature of a control box in the manner of heating the air in the insulation box. The external bionic mouse stomach silica gel model of the device is made of high-elasticity, high-stability and high-transparency addition type silicone rubber raw materials and has the form and size of the real mouse stomach and the details of the physiological structure. The device is easy to operate and convenient to wash, the comparison can be conveniently made with an internal live mouse experiment result, and the defects can be scientifically assessed and overcome.

Description

technical field [0001] The invention relates to a bionic dynamic rat stomach digestive system device, which can be used for effectively simulating the mixing, digestion and emptying process of various types and structures of food and medicine in the real rat stomach. Background technique [0002] At present, before any new functional food or drug is put into the market and trusted and accepted by consumers and patients, it must undergo strict experiments and evaluations in terms of nutritional value, toxicology, and pharmacology. To evaluate the release rate and utilization rate of its nutrients and effective active ingredients in the gastrointestinal tract, it is first necessary to understand their digestion and emptying process in the stomach, and understand their nutrient delivery process in the body, so as to improve the food and drug. Processing methods or construction of new functional foods can effectively improve the digestion and absorption of nutrients and the uti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G09B23/36
CPCG09B23/36
Inventor 陈晓东林旭奇陈利丁伍鹏
Owner NANTONG EAST CONCEPT NEW MATERIAL CO LTD
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