130results about "Chemical methods analysis" patented technology

The utility model relates to the technical field of environmental air pollutant concentration monitoring, and provides a peroxy radical chemical amplification device which comprises a sampling-amplification channel, a first acquisition control circuit module is arranged in the sampling-amplification channel and used for controlling an electric control program of a device system, and a second acquisition control circuit module is arranged in the sampling-amplification channel. An HO photolysis module is arranged in the sampling-amplification channel, a second acquisition control circuit module is arranged in the sampling-amplification channel and used for controlling an electric control program of the device system, and a gas path module is arranged in the sampling-amplification channel and used for controlling the gas flow direction of the device system; according to the utility model, the sampling-amplifying channel is arranged, so that the device is simple in structure, simple to operate, low in manufacturing cost and high in time resolution; the inhibition effect of the environment humidity on the amplification reaction is solved to a certain extent, and the actual effects of accurate measurement, simple operation and stable operation are obtained.

The invention discloses a saline-alkali soil crop-soil system nutrient dynamic matching regulation and control method, relates to the technical field of agricultural planting, and aims to solve the technical problems of saline-alkali soil nutrient imbalance, limited crop nutrient absorption and low efficiency of a traditional regulation and control mode, and the method comprises the following steps: S1, preparation before sowing; performing layered deep scarification treatment on a plough layer of the saline-alkali soil, synchronously applying a salt control improvement material to a deep plough layer to improve a saline-alkali environment, and arranging a layered under-film drip irrigation system matched with crop root zone distribution; s2, monitoring in a whole growth period; in the whole growth period of crops, plough layer soil samples are collected in a layered mode, soil salinity and nutrient indexes are measured, meanwhile, the growth state of the crops is monitored, and the incidence relation between the soil indexes and crop growth is established. The method solves the problem that nutrient supply is disjointed with the requirements of the root zone and the growth period of the oil sunflower in the prior art, creates adaptive saline-alkali environment and nutrient conditions for the whole growth period of the oil sunflower, and guarantees normal growth and development of the oil sunflower.

The invention provides a chemical computer having a matrix, an input device and an analytical device. The matrix is a plurality of interconnected reaction spaces holding a reaction mixture; the input device is provided to independently address each of a plurality of reaction spaces within the matrix; and the analytical device has a sensor to analyse a reaction characteristic of a reaction mixture in one or more reaction spaces. Also provides are methods for using the chemical computer, and the use of the chemical computer as a logic gate.

Described herein are methods, assays and techniques for detecting and / or measuring anti-drug antibodies that bind to a protein, polypeptide or other compound or molecule that comprises at least one immunoglobulin variable domain with an exposed C-terminal region.

Provided are an anti-CLDN18.2 antibody or antigen-binding fragment thereof, a nucleic acid molecule encoding the same, an immunoconjugate, bispecific molecule, chimeric antigen receptor and pharmaceutical composition comprising the same. The antibody or antigen-binding fragment thereof is used for preventing and / or treating a tumor.

This document provides methods and materials involved in treating cancer. For example, chimeric antigen receptor T cells having reduced levels of GM-CSF are provided. Also provided as methods for making and using chimeric antigen receptor T cells having reduced levels of GM-CSF.

The utility model discloses a device for evaluating the performance and loss of a desulfurizing agent based on a complex iron method, which relates to the technical field of complex iron desulfurization and specifically comprises a gas inlet module, a desulfurization module, a desulfurizing agent regeneration module, a sulfur precipitation module and a desulfurizing agent self-circulation module which are connected in sequence, the central control module is in communication connection with the monitoring module; the tail gas treatment module is connected with the desulfurization module; the desulfurization module adopts a desulfurization tower; the desulfurizing tower comprises a gas inlet, a gas outlet, a desulfurizing agent inlet and a desulfurizing agent outlet; the gas inlet module is connected with a gas inlet of the desulfurization module, a desulfurizer outlet of the desulfurization module is connected with the desulfurizer regeneration module, and a desulfurizer inlet of the desulfurization module is connected with the desulfurizer self-circulation module. According to the utility model, the data collected by the monitoring module is transmitted to the central control module, and the central control module receives and processes the data to obtain the performance index of the desulfurizing agent and the loss index of the desulfurizing agent, so that the performance of the desulfurizing agent and the loss of the desulfurizing agent are accurately evaluated in real time.

Provided is a method for analyzing fumed silica, which makes it possible to improve the accuracy of analysis of fumed silica, particularly analysis by a combustion method, to a level that has not been achieved before. [Solution] A sample of fumed silica is compacted using a fumed silica compaction jig that includes, for example, a cylindrical cylinder 1, a base 2 forming the bottom surface of the cylinder, and a cylindrical piston rod 3 that can be fitted into the cavity of the cylinder, preferably to a compacted body with a bulk density of 150 g / L or more, and the obtained compacted body is then subjected to analysis.

This invention discloses a simulation device for hydrothermal reactions under vacuum chamber dehydration accidents, belonging to the field of vacuum chamber accident simulation technology. The device includes a quartz tube with its opening facing upwards, an induction heating coil wound around its exterior, and a detachably sealed end of the quartz tube via a flange assembly. A water injection pipe extending from the lower end of the flange assembly to above a metal sample is connected to a storage tank. The flange assembly also has an outlet pipe communicating with the inner cavity of the quartz tube, which is connected to a mass spectrometer analysis unit via a liquid nitrogen cold trap. The middle section of the outlet pipe is connected to a vacuum pumping unit via a vacuum pumping pipe. A monitoring unit is located on one side of the quartz tube. This invention integrates vacuum acquisition, induction heating, controllable coolant injection, in-situ monitoring, and online analysis of gaseous products, achieving comprehensive simulation of the high-temperature metal-coolant hydrothermal reaction process under vacuum chamber dehydration accidents. It is suitable for preliminary research on vacuum chamber dehydration accidents in fusion devices, high-temperature high-vacuum furnaces, and other similar applications.

This invention relates to the field of thermal stability evaluation technology, and more particularly to a method and apparatus for evaluating the thermal stability of organic heat transfer fluids. The evaluation method includes: placing the organic heat transfer fluid in a loading container, introducing an inert gas to replace the air, sealing the container, and then conducting a high-temperature thermal test; after the high-temperature thermal test, cooling the loading container and then restoring it to atmospheric pressure; after the organic heat transfer fluid returns to room temperature, measuring the indicators of the organic heat transfer fluid, including kinematic viscosity, degradation rate, and pressure; scoring each indicator based on the kinematic viscosity change rate, degradation rate, and pressure increase value; and judging the thermal stability of the organic heat transfer fluid based on the comprehensive score. This invention provides a method and apparatus for evaluating the thermal stability of organic heat transfer fluids, enabling a rapid, efficient, and multi-dimensional evaluation method for the thermal stability of organic heat transfer fluids.

The utility model discloses a nitrogen determination device for food quality detection. The nitrogen determination device comprises a main body, an adjusting screw rod and a fixing mechanism, two sliding grooves are formed in the front end of the main body, and adjusting screw rods are in threaded connection with the interiors of the sliding grooves; the two fixing mechanisms are arranged on the adjusting screw rod in an array mode. The fixing mechanism comprises a mounting plate, an adjusting ring, a screw rod and a driving gear; top blocks are symmetrically arranged at the rear end of the mounting plate and are in threaded connection with adjusting screw rods; mounting groove mounting screws and driving gears are arranged at the upper end of the mounting ring in an array manner; the lower part of the mounting ring is rotationally connected with an adjusting ring; a circular ring is formed at the front ends of the screw rods in the mounting grooves arranged in the array; the screw rod is in sliding connection with the mounting groove, and the screw rod is in threaded connection with the driving gear; a replaceable sponge layer is arranged at the front end of the screw rod; the driving gear is in gear connection with the adjusting gear; the driving gear is controlled to rotate by rotating the adjusting ring, the screw rod is controlled to move back and forth, and the diameter of a circular ring formed at the front end of the screw rod in the mounting groove is adjusted.

The application relates to a forced oxidation test system, comprising: a forced oxidation subsystem, a first machine box, a second machine box and a connecting device; the inner cavities of adjacent forced oxidation subsystems are arranged in parallel; the forced oxidation subsystem comprises: forced oxidation parts, the inner cavities of adjacent forced oxidation parts are arranged in series; the packaging to be tested is placed on the first machine box; the second machine box is connected with the first machine box through the connecting device; the forced oxidation subsystem is installed on the second machine box, and the forced oxidation part is arranged opposite to the packaging to be tested; the second machine box is configured to act along the axis of the connecting device to the direction close to the packaging to be tested, and is sealedly installed into the inner cavity of the forced oxidation part on the packaging to be tested, so that the displacement gas in the inner cavity of the forced oxidation part penetrates into the packaging to be tested. The forced oxidation subsystems of the application can provide stable packaging to be tested with different oxygen permeation degrees for shelf life simulation test.

The invention provides an acid rock reaction kinetics testing device and method, and relates to the technical field of acid rock reaction kinetics test.The device comprises a reaction kettle, a rotation driving part is arranged in the reaction kettle, and the rotation driving part is used for being connected with a rock core sample and can drive the rock core sample to rotate in the reaction kettle; a first heating part is arranged on the outer side of the reaction kettle; the acid injection structure is connected with the liquid inlet pipeline of the reaction kettle, and the acid injection structure is used for being connected with a gas source; the cooling structure is connected with a liquid outlet pipeline of the reaction kettle; the reinjection structure is connected with an output pipeline of the cooling structure and is connected with the acid injection structure through a reinjection pipeline; the problems that in the acid rock reaction kinetics testing technology in the prior art, spraying of steam-state spent acid can affect the sampling precision of the spent acid and form potential safety hazards, and for a high-temperature and high-pressure reaction kettle, a large amount of time needs to be consumed for cooling after each test, and continuous testing cannot be conducted are solved.

To provide a method for analyzing the trace amount of a noble metal element contained in a solid sample containing a water-soluble tungsten oxide.SOLUTION: Disclosed is a method for analyzing at least one noble metal element in a solid sample containing a water-soluble tungsten oxide, which includes steps (1) to (3): (1) a firing step of firing a solid sample containing the water-soluble tungsten oxide in an oxidizing atmosphere to obtain a fired solid sample in which the water-soluble tungsten oxide is a tungsten oxide fired body; (2) an extraction step of extracting the noble metal element from the fired solid sample into an acidic aqueous solution to obtain an extract; and (3) a quantification step of measuring the concentration of each of the noble metal elements contained in the extract.SELECTED DRAWING: None

This invention relates to an ultra-high temperature and high pressure autoclave system and its testing method for supercritical water oxidation experiments. The autoclave module of the system includes a horizontal tubular autoclave body and a split cylindrical heater. The split cylindrical heater is fitted outside the horizontal tubular autoclave body. The steam inlet end of the horizontal tubular autoclave body is an integrated bottom, including an inner layer with small holes and an outer layer with steam inlet holes. A steam inlet cavity is formed between the outer and inner layers. The steam outlet end of the horizontal tubular autoclave body is sealed by a sealing pipe plug and a cylindrical flange. A steam outlet hole is opened on the sealing pipe plug, which communicates with the cavity of the horizontal tubular autoclave body. A central threaded hole coaxial with the steam outlet hole is opened on the cylindrical flange. A water treatment module, a water chemistry quality monitoring module, a liquid injection module, and a preheating module are connected to the steam inlet end of the horizontal tubular autoclave body through pipelines. The steam outlet end of the horizontal tubular autoclave body is connected to an explosion-proof module through a steam outlet hole. A temperature and pressure monitoring and regulation module is used to control the temperature and pressure at the steam inlet end.

The present disclosure relates to a method of isolating extracellular vesicles directly from human tissues. The invention further relates to a method of identifying disease and tissue specific membrane proteins on extracellular vesicles by membrane isolation and proteomic analysis. The invention further relates to methods of diagnosing diseases by capturing extracellular vesicles by the use of disease specific membrane proteins from body fluids, and detecting or analyzing molecular signatures (proteome, DNA, and RNA) on captured extracellular vesicles. Moreover, the present invention relates to kits, apparatus and software required for implementing aforementioned methods.

High levels of nuclear NMT1 are associated with longer relapse free survival in ERα positive breast cancer patients. Both low levels of cytosolic and nuclear NMT1 correlated to very poor clinical outcomes. NMT2 also plays an important function in breast cancer signalling, regulated through phosphorylation. For example, NMT2 phosphorylation status is a key element in the progression of ER+ breast cancer cells. Specifically, nuclear localization of NMT2 is associated with poor outcomes in breast cancer patients.

The application provides a testing method for carbon coating completeness of a silicon-based material, and belongs to the technical field of material testing. The method comprises the following steps: placing a first mass of strong alkaline material and a second mass of testing silicon-based material in a reaction tank to perform a reaction, and obtaining first current information output by a detection device; placing the first mass of strong alkaline material and a contrast material in the reaction tank to perform a reaction, and obtaining contrast current information output by the detection device; drawing a test image based on the first current information and the contrast current information; and calculating the carbon coating completeness of the testing silicon-based material based on the peak area and the peak current value of the testing silicon-based material in the test image, the peak area and the peak current value of the contrast material, and the second mass and the mass of the contrast material. The testing method for carbon coating completeness of the silicon-based material provided by the application can simply and conveniently test the carbon coating completeness of the silicon-based material.

This invention provides an in-situ heating and electrical testing apparatus and method for scanning electron microscopy (SEM). The apparatus includes a T-shaped sample stage, an in-situ heating and electrical testing chip, a probe card, wires, a vacuum flange with a BNC interface, a signal source meter, pins, and fixing studs. The in-situ heating and electrical testing chip is placed on the T-shaped sample. The probe card presses into contact with the heating and testing electrodes on the in-situ heating and electrical testing chip and leads out wires, simultaneously fixing the chip. The fixing studs secure the probe card to the T-shaped sample stage. The vacuum flange with the BNC interface connects the probe card and the signal source meter via wires. This invention provides in-situ heating, electrical testing, and microstructure observation functions for SEM, offering advantages such as rapid heating and cooling, low thermal drift, and low electromagnetic interference. It provides a platform for testing the performance of micro and nanomaterials and an experimental platform for preliminary screening of transmission electron microscopy (TEM) samples.

To provide an analytical method for accurately analyzing ammonia nitrogen in a sample containing relatively large amount of metal ions.SOLUTION: The analytical method of ammonia nitrogen includes processes for: adding chelation agent into the sample to capture metal ions; converting ammonium ions in the sample into gaseous ammonia by shifting the sample pH, after the metal ions capturing, to alkali side; separating the gaseous ammonia using a gas permeable membrane; casing the separated gaseous ammonia to be absorbed in absorbent to be converted into ammonium ions; and quantifying and analysing the ammonium ions absorbed in the absorbent by indophenol blue method.SELECTED DRAWING: Figure 1

The invention provides a method for determining the redox potential of soluble black carbon, and belongs to the technical field of environmental analysis. The method comprises the following steps: reducing the soluble black carbon by quinone reducing bacteria under an anaerobic condition, sterilizing, adding ferrihydrite, reacting the reduced soluble black carbon with ferrihydrite, measuring the total amount of generated Fe (II), and calculating the redox potential of the soluble black carbon by taking the electronic equivalent of a standard substance AQDS as a reference. According to the method, the electron transfer of the soluble black carbon in the natural environment is simulated by adopting the microbial reduction process, the result is closer to the real environment, the operation is simple and convenient, the repeatability is good, and the method is suitable for evaluating the electron shuttling capability of the soluble black carbon in the environment.

The present invention relates to pancreatic cancers and the use of biomarkers in biological samples for the diagnosis of such conditions, in particular pancreatic ductal adenocarcinoma. The biomarker panel comprises LYVE1, REG1 and TFF1. Methods of treatment are also provided, as well as kits useful in the diagnosis and treatment of pancreatic ductal adenocarcinoma. The present invention is particularly useful in detecting early-stage PDAC.

This invention provides a system and method that employs multiple measurements of various, relevant tissue states of a patient to detect and predict OH and similar conditions. These multi anatomic measurements are transformed by a multivariate algorithm to outputs that convey the diagnostic and prognostic risk of the disease of interest. This novel, multiple-measurement technique avoids use of a single measurement, which is generally unlikely to adequately extract sufficient information to drive a clinically useful test in the setting of complex system disease. The system and method herein thereby allows automated monitoring of currently stable patients who, are known or suspected to have OH and / or similar internal conditions on a substantially continuous basis.

The present invention is directed to a biological marker of ovarian cancer, including early stage ovarian cancer. Specifically, the present invention provides methods for detecting ovarian cancer in a subject which include detecting an expression level of the biological marker junction plakoglobin in blood of the subject. An expression level of junction plakoglobin that is higher than a reference expression level for junction plakoglobin indicates that the subject has ovarian cancer. Methods of identifying a subject having ovarian cancer and methods of determining if a subject is susceptible to developing ovarian cancer are also provided based on detecting the expression level of junction plakoglobin in blood of the subject. The present invention also extends to methods of treatment of ovarian cancer together with methods of screening a candidate therapeutic agent for use in treating ovarian cancer. Furthermore, compositions and kits for detecting ovarian cancer in a subject are provided, as well as a method of identifying a biomarker for a cancer, including ovarian cancer.

The present invention relates to the field of biotechnology, and in particular to a detection composition and a protein capture detection method. Provided is a detection composition, comprising a nucleic acid array probe and a protein-nucleic acid conjugate, wherein the nucleic acid array probe comprises a capture sequence, and the capture sequence is used for capturing the protein-nucleic acid conjugate. Simultaneous detection of ultra-high multiplex antibodies can be performed on a same tissue slice. Because spatial reduction of the antibody position depends on sequencing technology, the background staining problem caused by traditional immunohistochemistry and immunofluorescence color developing agents can be solved. In addition, negative control, positive control, and detection of an antibody under test can be carried out on the same tissue slice, a detection result can be determined more accurately, and a false-negative or false-positive result caused by traditional staining technology is eliminated.

The utility model relates to oil liquid detection technical field especially crude oil water content monitoring devices, including oil storage tank, still include: single -way pipe, single -way pipe sets up in the top of oil storage tank, piston, the piston sets up in the inside of oil storage tank, second drive assembly is connected on the piston, liquid collecting pipe, the liquid collecting pipe fixed communication is on the sealed end of single -way pipe top, the inner diameter of liquid collecting pipe is less than the inner diameter of single -way pipe, heating device is fixedly installed on the liquid collecting pipe, the utility model discloses through single -way pipe vertical downward movement and to oil water carries out the collection, can collect the liquid of different liquid level to reduce the influence of oil water layering to water content data, effectively improve the reflection of sampling data to overall data, improve the accuracy degree of monitoring data.

The invention provides a device, method and system for testing coke performance under a hydrogen-rich condition, and relates to the field of blast furnace smelting, and the device comprises a reactor, a heating furnace coating the reactor, and a water vapor generation device connected with the reactor; wherein the water vapor generating device comprises a water tank, heating equipment arranged at the bottom of the water tank, and an air inlet, a water inlet and an air outlet which are formed in the top of the water tank; wherein the heating equipment is used for heating water in the water tank so as to generate water vapor; carbon dioxide gas enters the water tank from the gas inlet to be preheated, and preheated reaction gas is generated; the water vapor and the preheated reaction gas are conveyed to the reactor through the gas outlet; the heating furnace is used for heating the reactor, so that the performance test of the to-be-tested coke sample is completed in the reactor. According to the method, the influence of water vapor and carbon dioxide on coke reactivity and post-reaction strength can be analyzed more accurately, and important data support is provided for development of a hydrogen-rich blast furnace ironmaking process.

The invention relates to the technical field of water quality detection, and discloses a chemical sensor for water quality detection and a preparation method, the chemical sensor comprises a handle and a chemical sensor main body, the upper side of the handle is rotatably provided with a rotating column, the upper side of the rotating column is fixedly connected with a mounting rod, and a mounting ring is arranged above the mounting rod; the chemical sensor main body is arranged above the mounting ring, a connecting rod is inserted into the inner side of the mounting ring, the chemical sensor main body is fixedly arranged at the upper end of the connecting rod, cavities are formed in the two sides of the mounting ring, and limiting mechanisms for limiting the connecting rod to move relative to the mounting ring are arranged in the cavities. A through groove is formed in the side wall of the grip. According to the chemical sensor for water quality detection and the preparation method, the overall length of the sensor can be adjusted, water quality at different depths can be conveniently detected, and after the chemical sensor is used, centrifugal dewatering can be carried out on the whole sensor of the device, so that water sample residues are effectively avoided.

To provide an inspection method that enables simple and quick detection of chemicals contained in grain powder.SOLUTION: A grain powder inspection method that clears the above challenge is provided, the method comprising forming a grain powder layer with a flat surface by placing grain powder on a substrate and pressing a flat plate against the grain powder, and applying a reagent solution on the flat surface of the grain powder layer for reaction. The reagent solution consists of a detection reagent that develops color or emits light when reacting with chemicals, and a solvent having a surface tension of 50 mN / m or less.SELECTED DRAWING: None