97results about How to "Consider sensitivity" patented technology

The embodiment of the invention relates to the field of immunodetection, in particular to a human serum amyloid protein A determination kit with high sensitivity and a wide detection range. The humanserum amyloid protein A determination kit comprises a reagent 1, a reagent 2 and SAA calibrators with different concentration gradients, wherein the reagent 2 comprises carboxylated latex microspheresonly labeled with human SAA monoclonal antibodies and carboxylated latex microspheres only labeled with human SAA polyclonal antibodies; the average particle size of the carboxylated latex microspheres only labeled with the human SAA monoclonal antibodies is larger than the average particle size of the carboxylated latex microspheres only labeled with the human SAA polyclonal antibodies. The kitcan be used for detecting a single sample within 10 minutes; the kit has the advantages that the kit is simple in structure and excellent in precision, accuracy, linearity, interference resistance andother indexes, can well diagnose early inflammation of infectious diseases, can detect the content of SAA in serum and the content of SAA in blood plasma, is very suitable for clinical biochemical analyzers, and greatly facilitates clinical examination.

The invention discloses a flow monitoring point optimizing arranging method for water supply pipe network leakage fault diagnosis. The method includes adding virtual nodes in the middle of each pipe section of a pipe network topological model where pipe explosion or water leakage happens possibly to simulate happening of pipe network explosion accidents by adding node outlet flow at the position of the virtual nodes. When the accidents happen, flow of pipe sections in the whole pipe network can be affected to different extents. For example, flow change value in the pipe section to be inspected is set, and effect rate, namely, sensitivity of water leakage quantity of the pipe section of the virtual section on flow change produced at the position of the pipe section can be expressed. Flow monitoring points are arranged at the pipe sections with high sensitivity, and the monitoring quantity can be mutually independent. A target function optimally arranged is built according to the principle to obtain optimum monitoring point combination results. The method is characterized in that the target function related with the flow sensitivity is built based on flow information monitoring, and the target function is further optimized and calculated to obtain optimum monitoring point combination results.

The invention relates to the field of biotechnology, and more specifically to a fusion gene detection method. The method for efficient and economical detection of fusion genes provided by the invention includes: (1) core gene screening: selecting a core genome combination participating in fusion according to the tumor type; (2) core gene hybrid capture probe design: conducting imbricated full coverage probe design on the core gene obtained in step (1); (3) sequencing library construction: extracting the genomic DNA or transcriptome RNA of the a to-be-detected sample, and constructing an initial library; (4) probe hybrid capture: subjecting the probe synthesized according to step (2) and the initial library obtained by step (3) to hybrid capture reaction; and (5) high-throughput sequencing:conducting high-throughput sequencing on the probe hybrid captured core gene participated fusion gene; and (6) bioinformatic analysis: screening the sequencing data to obtain the fusion gene detection result. The method is fast, efficient and comprehensive.

The invention discloses a variable transmission ratio optimization design method of a multi-mode drive-by-wire power steering system and a special system thereof. The method comprises the following steps: 1) establishing a drive-by-wire power steering system dynamic model; 2) establishing road feel and sensitivity evaluation indexes of the steer-by-wire system; Step 3) starting to increase progressively at the speed of 25km/h, and setting 10 groups of vehicle speeds; 4) taking the steering transmission ratio as an optimization variable, determining the transmission ratio under the fixed yaw velocity gain and the fixed lateral acceleration gain according to the automobile parameters and the automobile speed, taking the transmission ratio as a design space of the transmission ratio, and taking the steering road feel and the steering sensitivity as optimization objectives to establish a multi-objective optimization model; Step 5) According to the transmission ratio optimization result, adopting the smooth curve to perform fitting to obtain an optimized design result. According to the transmission ratio optimization method of the steering system, through further optimization design ofthe transmission ratio of the steering system, the road feel and sensitivity of automobile steering are considered, the comprehensive performance of the steering system can be effectively improved, and the driving experience of a driver is improved.

The invention provides a differential protection method based on an adaptive ratio braking curve. The method comprises the following steps: sampling three-phase current on each side of a transformer; calculating a differential current phasor value and a braking current phasor value; performing phase current break variable calculation on each sampled phase current instantaneous value, and judging whether a phase current break variable criterion is satisfied; after the break variable criterion is satisfied, starting a timer to start timing, and inputting two-broken-line braking characteristics within a set time T1; and logging out the two-broken-line braking characteristics after the time T1, and inputting three-broken-line braking characteristics with stronger braking property. By adoption of the differential protection method provided by the invention, the objective of preventing maloperation by the three-broken-line braking characteristics with stronger braking property after removing an internal fault by using the two-broken-line braking characteristics with higher sensitivity and removing an external fault is achieved, the defect that both of the sensitivity and the safety of the protection cannot be achieved resulting from that a single braking curve is adopted in conventional differential protection is overcome, and the protection action performance is improved, therefore the differential protection method has a great engineering application value.

The invention relates to a micro-fluidic chip, a kit and an application method of the kit. A base body of the micro-fluidic chip is provided with a positioning groove, a sample cavity, a lysis solution storage cavity, a sample lysis cavity, a cleaning solution storage cavity, an eluent storage cavity, a buffer cavity, a nucleic acid cavity, a waste liquid cavity, a distribution pipeline and at least two PCR reaction cavities; and the base body is further provided with a protease solution storage cavity, a mixing cavity, a filtering area and a selection cavity. The number of PCR reaction cavities can be set when the chip is applied to detection; a fluorescent PCR detection method is combined with a micro-fluidic technology, the advantages of the two technologies are complementary, the defects of the two technologies are avoided, the possibility of leakage of samples or chemical reagents is avoided, the possibility of nucleic acid pollution is greatly reduced, related pathogenic bacteriain the samples can be quickly and accurately identified, the kit is particularly suitable for realizing multiple detection, and the experimental time and cost are saved; and the requirements on operation environment, personnel skills and the like are low, the automation degree is high, the consumed time is short, and the performance indexes such as specificity and sensitivity of detection can beconsidered.

The invention belongs to the field of relay protection of a power system, and relates to a split-phase differential protection method based on scalar product brake criterion normalization. The method comprises the following steps of: acquiring the currents on the two sides of a transmission line by utilizing current transformers (CTs) on the two sides of the transmission line; calculating the amplitude values, the phase angles and the phase angle difference between the currents on the two sides by utilizing a full-wave Fourier algorithm; if the phase angle difference between the currents on the two sides is less than 120 degrees, determining that an internal fault exists, performing the protection action of tripping; and if the phase angle difference between the currents on the two sides is more than 120 degrees, turning to the amplitude value judgment below: first, judging whether the amplitude values of the currents on the two sides are both greater than three times the rated current of the primary side of the CT, wherein if the amplitude values are both greater than three times the rated current of the primary side of the CT, the proportionality factor K=2, and if the amplitude values are not greater than three times the rated current of the primary side of the CT, the proportionality factor K=0.8; and then calculating the ratio of the smaller amplitude value to the greater amplitude value of the currents on the two sides, wherein if the ratio is less than the K, determining that an internal fault exists, and performing the protection action of tripping. According to the split-phase current differential protection method of the transmission line provided by the invention, the sensitivity of the internal fault and the selectivity of an external fault are taken into consideration.

A power tool has a handle assembly which is biased by a torsional spring. The torsional spring has an engaging arm the position of which is fixed relative to the housing by adjusting means. The adjusting means has a lever which extends outside the housing of the power tool, and a cam surface, and is mounted on and rotatable at least partially around an axle. In use, the tension in the torsional spring may be adjusted by movement of the adjusting means. The lever is moved, causing rotation of the adjusting means around the axle. As a result, the cam surface causes the engaging arm of the spring to be moved axially along the axle and more or less tension is applied to the torsional spring.

The invention discloses a colloidal gold test strip for rapid detection of Human enterovirus 71 (EV71) IgM (immunoglobulin m), belonging to the field of medical detection consumables. The colloidal gold test strip is characterized in that a colloidal gold-labeled cellulose pad is coated with colloidal gold-labeled EV71 antibody; a control line C is coated with anti-mouse IgG polyclonal antibody; a test line T is coated with anti-Mu chain monoclonal antibody; and a sample cellulose pad is coated with EV71 recombinant antigen. The inventive test strip adopts antibody capture principle and colloidal gold technology to detect EV71 IgM in serum/plasma/whole blood samples simply, sensitively, precisely and rapidly; and can be used for the rapid detection of EV71 IgM and diagnosis of hand-foot-mouth disease.

The embodiments of the invention relate to the field of immunoassay, and in particular to a human heparin binding protein assay kit with high sensitivity and wide detection range. The human heparin binding protein assay kit comprises: a reagent 1, a reagent 2 and human HBP calibrators with different concentration gradients. The reagent 2 comprises a carboxyl latex microsphere labeled only with human HBP monoclonal antibody and a carboxyl latex microsphere labeled only with human HBP polyclonal antibody. The average particle diameter of the carboxyl latex microsphere labeled only with the humanHBP monoclonal antibody > the average particle diameter of the carboxyl latex microsphere labeled only with the human HBP polyclonal antibody. The human heparin binding protein assay kit provided bythe invention can complete a single sample test within 10 minutes, and indexes of precision, accuracy and anti-interference are excellent. The invention can be used clinically to predict an organ dysfunction caused by sepsis, and can be used as an early diagnostic marker for sepsis, especially serious bacterial infection.

The invention discloses a method for turning on a screen of an intelligent watch by raising a hand. The method adopts a gravity sensor module to acquire component data of gravity acceleration in the X direction and the Y direction of a display screen of the intelligent watch, namely, X-axis acceleration and Y-axis acceleration, takes M groups of the X-axis acceleration and the Y-axis acceleration as a judgment object, and judges whether a gesture action corresponding to the judgment object conforms to a hand raising gesture rule. The hand raising gesture rule is used for judging whether the Y direction changes from a negative direction to a positive direction, whether the magnitude of an absolute value of a numerical value of the Y-axis acceleration changes slowly and whether the magnitude of an absolute value of a numerical value of the X-axis acceleration changes slowly from the beginning when a user raises the hand wearing the intelligent watch to the final stage when the user looks at the display screen of the intelligent watch. Therefore, whether the current gesture action conforms to the hand raising gesture rule or not is at least regarded as a hand raising screen turning-on condition for controlling whether the display screen is turned on, thereby realizing the hand raising screen turning-on function of the intelligent watch. The method provided by the invention can be used for automatically turning on the display screen when the user raises the hand to look at the intelligent watch.

The invention discloses a wafer edge defect detection method. When a wafer edge defect detection program is created, signals of a whole detection region of the wafer edge are acquired firstly, the scanning area of the acquired whole detection region is simulated and expanded into a rectangular plane, the width of a detection light source serves as a scanning interval criterion so that the rectangular plane can be divided according to the equal area, according to different requirements of defect detection, different scanning interval numbers are selected for conducting scanning detection on wafer edge defects, according to the flexibility requirements of different defects, wafer edge scanning methods conducted at different speeds are flexibly selected, rapid scanning operation is achieved, and detection flexibility is considered as well.

The invention discloses a method and a device for controlling the motion of a trackball cursor. The method comprises the following steps: A1, the rotating speed or the displacement within a fixed time interval of a trackball are detected in real time; and B1, a ruler between the rotating displacement of the trackball and the displacement of the cursor on a display screen is arranged in real time according to the variation of the rotating speed or the variation of the displacement within the fixed time interval of the trackball, and the ruler becomes larger when the rotating speed or the displacement within the fixed time interval is increased. The method and the device for controlling the motion of the trackball cursor simultaneously consider the sensitivity requirement and the precision requirement and effectively inhibit error movement of the trackball.

The invention relates to an inrush current recognition method and a low-voltage and medium-voltage quick disconnection protection method utilizing same. The technical scheme includes that a secondary harmonic locking criterion and a locking criterion by a waveform comparison principle are adopted to judge phases or logics on the basis of self quick disconnection overcurrent criteria of a circuit (while keeping the direction and low-voltage locking selective), phase-separation locking is realized, and the inrush current recognition with a low-voltage open criterion is adopted and differentiates magnetizing inrush current from fault current of an air-dropped distribution transformer when the circuit in a power distribution network is manually closed or repeatedly closed. Accordingly, reliability of quick disconnection protection is guaranteed while speediness of the quick disconnection protection is ensured.

The embodiment of the invention relates to the field of immunodiagnosis, in particular to a human alpha1-microglobulin (MG) determination kit with high sensitivity and a wide detection range. The human alpha1-MG determination kit provided by the embodiment of the invention comprises a reagent 1, a reagent 2 and human alpha1-MG calibration products of different gradient concentrations, wherein thereagent 2 comprises carboxylated latex microspheres labeled with a human alpha1-MG monoclonal antibody only and carboxylated latex microspheres labeled with a human alpha1-MG polyclonal antibody only;and the average particle size of the carboxylated latex microspheres labeled with the human alpha 1-MG monoclonal antibody only is larger than that of the carboxylated latex microspheres labeled withthe human alpha 1-MG polyclonal antibody. The human alpha1-MG determination kit provided by the invention can complete the detection of a single sample within 10 minutes with excellent precision, accuracy and anti-interference performance, can well reflect the renal tubular reabsorption function and glomerular filtration function, is very suitable for clinical biochemical analyzers, and greatly facilitates clinical examination.

The invention discloses an immunodetection method of 25-hydroxyvitamin D. The immunodetection method comprises the following steps of pairing a No.3 antibody of anti-25-hydroxyvitamin D and a No.22 antibody of anti-25-hydroxyvitamin D, and respectively capturing and detecting a conjugate of 25-hydroxyvitamin D-macromolecular protein to form a double-antibody sandwich compound; the application comprises a lateral chromatography platform, an enzyme-linked immunosorbent assay (ELISA) platform, a chemiluminescence platform, a microfluidic platform and an immunoturbidimetric platform. The invention discloses an immunodetection method of 25-hydroxyvitamin D and an application thereof and relates to the field of immunodetection methods. The immunodetection method is advantaged in that project development difficulty is reduced, development cost is saved, development efficiency is improved, and the immunodetection method can be combined with 25-hydroxyvitamin D in a sample, so reagent performance is improved, the amount of effective competitive antibodies is much larger than that of conventional methods, so both sensitivity and reactivity can be considered, and the linear range can also be increased.

A magnetic sensor system, particularly for transport systems, including a ferromagnetic generator which can be moved relative to a magnetic sensor. The magnetic sensor is arranged in the magnetic fields of at least two adjacent magnets in whose magnetic field the generator can be moved. The magnetic fields are constructed as two overlapping lobes, whereby the positioning of the generator can be detected particularly well.

The invention relates to the field of immunoassay, and in particular to a human anti-Mullerian hormone assay reagent kit with high sensitivity and the wide detection range. The human anti-Mullerian hormone (AMH) assay reagent kit comprises a reagent 1, a reagent 2, and human AMH calibrators of different gradient concentrations, wherein the reagent 2 comprises carboxylate latex microspheres labeledonly with human AMH monoclonal antibodies and carboxylate latex microspheres labeled only with human AMH polyclonal antibodies, and the average particle diameter of the carboxylate latex microsphereslabeled only with the human AMH monoclonal antibodies is greater than that of the carboxylate latex microspheres labeled only with the human AMH polyclonal antibodies. According to the human AMH assay reagent kit, detection of a single sample can be finished within 10 minutes, and indexes such as precision, accuracy and interference resistance are excellent.

The invention discloses an adjuvant for animal vaccines, and a preparation method and application thereof. The adjuvant for animal vaccines comprises the following raw materials by volume: 75 to 90% of low-density mineral oil, 1 to 10% of octyl and decyl glycerate and Span-80, 0.5 to 5% of glycerin and polyglycerol isostearate and 1 to 10% of polyethylene glycol-12-hydroxystearate-15, Tween-80 and propylene glycol, wherein the amount of Tween-80 is in a range of 0 to 5%. The preparation method comprises the following steps: weighing the low-density mineral oil; then adding octyl and decyl glycerate, Span-80, glycerin, polyglycerol isostearate, 1 to 10% of polyethylene glycol-12-hydroxystearate-15, Tween-80 and propylene glycol; and carrying out mixing and standing. The adjuvant provided by the invention has safety, stability and self-emulsifying performance, has low sensitivity to temperature in the process of emulsification, can form a water-in-oil-in-water spatial structure, and is extensively applicable to preparation of animal vaccines.

The invention discloses a fiber bragg grating soil pressure sensor which comprises a pressure disc, a strain beam and a base. The strain beam comprises a middle part used for conducting pressure, twoends used for fixing and two cantilevers located between the middle part and the two ends respectively, the two ends of the strain beam are erected on the base, and the middle of the strain beam is suspended. The center of the pressure disc is provided with a downward boss which is crimped with the middle part of the strain beam; and at least one cantilever of the strain beam is pasted with one ormore fiber bragg gratings, and the fiber bragg grating sensor is used for sensing deformation of the cantilever caused by the pressure conducted to the middle part of the strain beam by the boss of the pressure disc. According to the fiber bragg grating soil pressure sensor provided by the invention, the strain beam is adopted to replace a strain film, so that errors caused by uneven pressure distribution can be reduced.