The present application discloses a
lactic acid pediococcus SWU-HX39 with the function of reducing
uric acid, and the classification name is
lactic acid pediococcus (
Pediococcus acidilactici)
Pediococcus acidilactici ), which is preserved in the China General
Microbiological Culture Collection Center, with the preservation number of CGMCC No.33055, the preservation date of December 13, 2024, and the preservation address of No.3, Xili, Beichen West Road, Chaoyang District, Beijing. The
lactic acid pediococcus SWU-HX39 can relieve the
kidney damage caused by high
uric acid, reduce the synthesis of
uric acid, lower the concentration of uric acid in blood, improve the
excretion of uric acid in the body, reduce the
reabsorption of uric acid in the body, and achieve the effect of reducing uric acid. In addition, SWU-HX39 can reduce the expression of LPS and the expression of
inflammatory factors IL-1beta, IL-6 and TNF alpha. That is, it has the functions of anti-
inflammation and relieving liver
inflammation, and can also increase the content of SCFAs in the body of patients with high uric acid, especially propionic acid, so as to reduce the uric acid level and improve the abnormal uric
acid content.