443 results about "Breast milk" patented technology

The invention belongs to the field of food, and particularly relates to a nutritional composition containing probiotics and breast milk oligosaccharide for improving anxiety or depression and application of the nutritional composition. The invention provides application of a nutritional composition in preparation of food beneficial to improving constipation and anxiety state and / or depression state caused by constipation. Wherein the nutritional composition comprises the following components (i) and (ii): (i) a bifidobacterium probiotic, and (ii) a sialylated breast milk oligosaccharide; the bifidobacterium probiotics at least comprise animal bifidobacterium subsp. Lactis, the sialylated breast milk oligosaccharide at least comprises 6 '-sialylated lactose, and the animal bifidobacterium subsp. Lactis comprises a Bb-12 strain. The substance combination of the bifidobacterium probiotics and the sialylated breast milk oligosaccharide can synergistically improve abnormal brain-intestine interaction, and improve constipation and anxiety and / or depression state caused by constipation.

The invention belongs to the technical field of microorganisms, and particularly relates to bifidobacterium longum subsp. Longum as well as a composition, a pharmaceutical composition, a culture, a food product or a dietary supplement containing the bifidobacterium longum subsp. Longum and application of the bifidobacterium longum subsp. Longum. The bifidobacterium longum is preserved in the Guangdong Microbial Culture Collection Center on January 21, 2025, and the preservation number is GDMCC (China General Microbiological Culture Collection Center) No.65836. The bifidobacterium longum subsp. Longum has relatively strong gastric acid and cholate tolerance and intestinal colonization capability; the bifidobacterium longum subsp. Longum can effectively utilize bifidobacterium bifidum to release monosaccharide or disaccharide outside cells for efficient proliferation, and the composition containing the bifidobacterium longum subsp. Longum, the bifidobacterium bifidum and breast milk oligosaccharide can release a large amount of short-chain fatty acid, so that the effects of maintaining the physiological function of an organism and improving the health of the organism are achieved.

The invention relates to a bifidobacterium longum subsp. Infantis Imu-01 and an application thereof. Specifically, the invention provides bifidobacterium longum subsp.infantis Imu-01, a culture, a preparation and application of the bifidobacterium longum subsp.infantis Imu-01 in preparation of a product for improving the immune function. The bifidobacterium longum subsp. Infantis provided by the invention can regulate and control the immune level of an object, improve the content of butyric acid in intestinal tracts and improve the utilization of oligosaccharide in breast milk.

The invention provides a breast milk feeding amount intelligent calculation and dynamic adjustment method and system, and relates to the technical field of intelligent feeding, and the method comprises the steps: collecting real-time physiological parameters of an infant, constructing an infant digital model through a multi-scale morphological neural network, calculating a basic energy consumption value through combining with a biological rhythm prediction model, and calculating the feeding amount of the infant. The standard breast milk feeding amount is calculated through the self-adaptive fuzzy neural network; the method comprises the following steps: collecting mother physiological state data and breast milk component data, calculating a breast milk nutrition density coefficient by using a deep mixing cognitive network and an immune evolution self-organizing network, correcting a breast milk reference feeding amount, and finally calculating an actual breast milk feeding amount through a self-adaptive resonance theory network; growth and development data of an infant after breast milk intake are collected, a multi-layer spiral pulse neural network is used for extracting development feature vectors, a development deviation value is calculated based on a fractal dynamics model, network parameters are dynamically adjusted through a biological group intelligent optimization system, and dynamic optimization of breast milk feeding amount is achieved.

The invention provides a milk powder composition containing breast milk oligosaccharide and easy to digest and absorb. The milk powder composition comprises the breast milk oligosaccharide, OPN, galactooligosaccharide, lactoferrin, alpha-whey protein, multivitamins, lactose, vegetable oil and compound minerals, wherein the weight ratio of the lactoferrin to the OPN to the breast milk oligosaccharide to the galactooligosaccharide is 1: (2-4): (2-50): (4-100). The composition can effectively recover and improve the intestinal barrier function caused by inflammatory factors, can be well absorbed by infants with poor digestion and absorption functions, reduces diarrhea and promotes skeletal development.

The invention belongs to the field of food, and particularly relates to a nutritional composition of oligosaccharide and probiotics and application of the nutritional composition. The invention provides application of a nutritional composition in preparation of food beneficial to improvement of constipation and improvement of cognitive competence decline caused by constipation. Wherein the nutritional composition comprises the following components (i) and (ii): (i) a neutral fucosylated breast milk oligosaccharide, and (ii) a bifidobacterium probiotic; wherein the neutral fucosylated breast milk oligosaccharide at least comprises 2 '-fucosylated lactose, and the bifidobacterium probiotics at least comprise bifidobacterium longum subsp. Longum. According to the present invention, with the substance combination of the neutral fucosylated breast milk oligosaccharide and the bifidobacterium probiotic, the abnormal brain-intestine interaction can be improved, such that the constipation can be easily improved, and the cognitive ability reduction caused by the constipation can be easily improved;

The present application relates to a kind of Bifidobacterium longum infantis subsp.Imu-01 and its application. Specifically, the present application provides Bifidobacterium longum infantis subsp.Imu-01, culture, preparation and preparation of immune function improving product application. The present application provides that Bifidobacterium longum infantis can regulate the immune level of the subject, improve the content of intestinal butyric acid, improve the utilization of human milk oligosaccharide.

The invention discloses a method for rapidly determining the content of breast milk oligosaccharide in dairy products, which comprises the following steps: sampling and pretreating different types of dairy products according to sample states, carrying out ultrasonic extraction, refrigerated centrifugal degreasing and centrifugal ultrafiltration protein purification on the obtained sample, and reducing the purified sample solution by using sodium borohydride to obtain a sample solution to be detected; reducing the breast milk oligosaccharide standard substance by sodium borohydride to obtain a standard solution to be detected; determining the standard substance solution and the to-be-detected sample solution by adopting ultra-high performance liquid chromatography-tandem mass spectrometry, establishing a standard curve, and carrying out quantitative analysis on the to-be-detected sample solution; the chromatographic conditions are as follows: an ACQUITY UPLC BEH Amide hydrophilic interaction chromatographic column is adopted; the mobile phase A is 20 mmol / L ammonium formate; the mobile phase B is acetonitrile; and gradient elution.

The invention relates to a traditional Chinese medicine composition with functions of tonifying qi and nourishing blood for livestock. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-30 parts of astragalus membranaceus, 10-40 parts of spina gleditsiae, 10-20 parts of angelica sinensis, 10-20 parts of codonopsis pilosula, 10-30 parts of uniflower swisscentaury root, 10-30 parts of ligusticum wallichii, 10-20 parts of cowherb seed, 10-20 parts of fruit of liquidambar formosana hance and 1-10 parts of iron sucrose. The traditional Chinese medicine composition is scientific and reasonable in component, free of toxic and side effects and medicine residue, convenient to take and low in cost, has the functions of tonifying qi and nourishing blood, stimulating the menstrual flow and prompting lactation, and is capable of effectively treating diseases of postpartum hypogalactia, breast milk stoppage and the like which are normal in livestock.

A breast pump device is disclosed. The breast pump device includes a primary machine portion, and a secondary control portion provided separately from the primary machine portion. The primary machine portion further includes a main housing, a pump attached to the main housing and configured to generate a pressure to cause breast milk to be expressed by a user of the breast pump device, and a milk container coupled to the pump and configured to accommodate the breast milk. The secondary control portion is electrically coupled to the primary machine portion without an airway and configured to remotely operate the primary machine portion.

The invention belongs to the technical field of microbial engineering, discloses a composition for promoting infant brain development and application thereof, and provides a composition containing lactobacillus paracasei N1115, breast milk oligosaccharide and whey protein powder, the composition can promote infant brain and nerve development, all the components have a synergistic effect, and the effect of promoting infant brain and nerve development is achieved. The conversion from latent TGF-beta in the whey protein powder to activated TGF-beta is activated, so that the aims of promoting neurodevelopment, improving memory and promoting brain development of infants are fulfilled. The preparation method is suitable for preparing milk powder, cheese, yoghourt, plant-based yoghourt and derivative products or other foods for promoting brain development of infants.

The invention relates to the technical field of detection of breast milk oligosaccharides, and provides a method for detecting breast milk oligosaccharides by ion exchange chromatography tandem mass spectrometry, which comprises the following steps: detecting a breast milk sample by ion exchange chromatography tandem mass spectrometry to obtain at least 42 breast milk oligosaccharides. According to the technical scheme, the problem that high-throughput detection of breast milk oligosaccharide is difficult to realize in related technologies is solved.

The invention belongs to the technical field of biology, and particularly relates to bifidobacterium longum subsp.infantis FMBL B250020GXY for metabolizing breast milk oligosaccharide and application of the bifidobacterium longum subsp.infantis FMBL B250020GXY, the bifidobacterium longum subsp.infantis FMBL B250020GXY is preserved in China Center for Type Culture Collection on September 1, 2025, and the preservation number is CCTCC M 20251931; three kinds of breast milk oligosaccharides, namely 2 '-fucosyllactose (2'-FL), lactose-N-neotetraose (LNnT) and lactose-N-tetraose (LNT), can be metabolized; plant source carbohydrates such as fructo-oligosaccharide and synanthrin can be metabolized; the compound has a relatively strong capability of removing DPPH and ABTS free radicals; a good inhibition effect is achieved on common pathogenic bacteria; good tolerance to acid and cholate is achieved; the strain is sensitive to gentamicin, streptomycin, tetracycline, chloramphenicol and vancomycin; the compound can be used for preparing antioxidant products, medicines for inhibiting pathogenic bacteria, infant foods and fermented foods, and has a wide application prospect.

The invention belongs to the technical field of nutritional compositions, and discloses a breast milk oligosaccharide-containing composition for promoting brain metabolism and relieving diarrhea and application of the breast milk oligosaccharide-containing composition, and the breast milk oligosaccharide-containing composition contains breast milk oligosaccharide consisting of 2 '-fucosyllactose, 3'-sialic acid lactose and 6 '-sialic acid lactose in a specific weight ratio. The composition disclosed by the invention is used for preparing products with the functions of promoting brain development or metabolism and relieving diarrhea. The composition prepared by the invention can be used for preparing formula milk powder, yoghourt and various metabiotics preparations with corresponding effects.

A simulative breastfeeding device is provided. The device is comprised of an upper body-worn garment. The garment has an interior pocket that receives at least one reservoir. The reservoir is shaped like a breast and is comprised of an areola and a nipple. During use, the reservoir can be filled with breast milk and / or infant formula and placed into the interior pocket such that the areola and nipple extend outwards from an opening in the garment. Therefore, a user can wear the garment and breastfeed an infant (in a simulated manner) via the reservoir and nipple.

The present disclosure relates to a composition for balancing the immune system of a neonatal or infant subject, the composition comprising an effective amount of 2 '-fucosyllactose, 3-fucosyllactose, 3'-sialyllactose, 6 '-sialyllactose, and lactose-N-tetrasaccharide.

The invention discloses a nutritional composition for promoting central nervous system development and application. The invention provides a nutritional composition for promoting the development of a central nervous system. The nutritional composition comprises the following necessary components: a breast milk oligosaccharide component and a casein phosphopeptide component, moreover, in the composition, the mass ratio of the breast milk oligosaccharide component to the casein phosphopeptide component is (1-100): (500-1). According to the invention, the breast milk oligosaccharide component and the casein phosphopeptides are matched to prepare the nutritional composition, and the nutritional composition can significantly promote nerve development such as neuronal maturation, synaptic generation and myelin sheath formation.

The invention provides a composition for promoting differentiation of intestinal immune cells as well as a preparation method and application of the composition. According to the composition, 1, 3-dioleic acid-2-palmitic acid triglyceride and breast milk oligosaccharide are used in a combined manner, so that monocytes can be effectively promoted to differentiate into intestinal macrophages, and inflammation is reduced to a certain extent. After the monocytes are differentiated into the intestinal macrophages, the intestinal immune homeostasis and intestinal microbiota inflammatory response can be regulated, so that the mucosal immune homeostasis and intestinal epithelial cell barrier function are maintained. Therefore, the composition provided by the invention can improve the intestinal immune barrier by promoting the monocytes to differentiate into the intestinal macrophages, and provides a new thought for improving the early intestinal barrier of infants through nutritional supplement.

The invention discloses a method and system for evaluating breast milk nutritional ingredient composition by using a multivariate statistical method and application, and belongs to the field of nutritional ingredient evaluation.The method comprises the following steps that the content of nutritional ingredients in to-be-evaluated breast milk or formula food is obtained to serve as an original data variable; carrying out normalization processing on original data variables to eliminate dimensional differences, and carrying out centralization processing; inputting the centralized data into a pre-constructed evaluation model to obtain a score output by the evaluation model, comparing the score with a preset median, and if the difference value is smaller, indicating that the result is closer to breast milk; wherein the evaluation model comprises four common factors obtained through principal component analysis and a scoring model obtained through loads and influence degrees in factor analysis. According to the method, macro nutrients and micronutrients of the breast milk are simplified by adopting a principal component multivariate statistical method, and main indexes are selected from numerous quality evaluation indexes to evaluate the nutritional ingredients of the breast milk or the formula food.

1. The name of the product under this design: Portable Breast Milk Cooling Cup (BW01). 2. Purpose of this product: This product is used to keep beverages hot or cold. 3. The key design point of this appearance design product lies in the overall shape of the product. 4. The picture or photo that best illustrates the key points of the design: 3D image of component 1. 5. Other situations that require explanation Other explanations: The portable breast milk cooling cup (BW01) includes component 1, the insulation cup body, component 2, the insulation cup liner, and component 2, the insulation cup liner is detachable.

The invention relates to the technical field of maternal and infant health, in particular to a breast feeding intelligent guidance and milk component analysis system, which comprises a milk component analysis module for generating a milk component analysis result by collecting spectral data of a breast milk sample, the lactation posture evaluation module and the computer vision module are used for evaluating lactation posture quality and collecting milk appearance and infant sucking behavior image data respectively, the data processing module is used for integrating the data and generating a comprehensive analysis result, and the feeding scheme generation module is used for creating a personalized feeding scheme based on the result and providing a personalized feeding scheme for the infant. The remote guidance module transmits an analysis result to a professional, obtains guidance suggestions and integrates the guidance suggestions into a personalized feeding scheme, and the user interface module displays the scheme and the suggestions and receives feedback, so that rapid detection of milk components and objective evaluation of lactation postures are realized, and family daily detection and accurate guidance become possible.

The invention discloses a breast milk fat globule membrane protein simulation degree evaluation method based on multi-dimensional similarity weighted fusion, and the method comprises the steps: constructing a breast milk MFGM proteomics database, and obtaining the proteomics data of a to-be-evaluated sample; the method comprises the following steps: obtaining a reference matrix through row screening and column screening based on a breast milk MFGM proteomics database, performing logarithmic transformation on the reference matrix, calculating a mean value and a standard deviation of each feature in the reference matrix, and constructing a Z-score matrix and a missing mask matrix corresponding to the reference matrix; calculating abundance distribution similarity and missing mode similarity of the to-be-evaluated sample; setting a shrinkage coefficient based on the actual overlapping feature number, screening a core protein set according to a set threshold value, and comparing to obtain the missing MFGM protein type of the to-be-detected sample; and constructing a Top-K neighbor center, calculating the feature deviation contribution and abundance difference of the to-be-evaluated sample, and outputting key defect proteins and formula optimization suggestions according to preset feature importance indexes. And the similarity simulation accuracy is improved.

1. Name of the product in this design: Milk bag. 2. Purpose of this design: For storing breast milk. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The present application belongs to the field of functional substance research, and particularly relates to a nutritional composition for promoting brain development and use thereof. The nutritional composition provided by the present application comprises essential active ingredients shown in (i) and (ii) as follows: (i) lysophosphatidylethanolamine; (ii) 3'-SL; wherein the essential active ingredient shown in (i) at least comprises lysophosphatidylethanolamine with a fatty acid chain with a length of 14-22 carbon atoms connected at the sn-1 position, and in the nutritional composition, the mass ratio of the essential active ingredient shown in (i) to the essential active ingredient shown in (ii) is 1:(1-450). The combination of lysophosphatidylethanolamine and breast milk oligosaccharide 3'-SL can effectively promote the overall development of the body, especially the brain development, and improve the relative gene expression amount of brain-derived neurotrophic factor and glial cell-derived neurotrophic factor in brain tissue, thereby effectively assisting the improvement of cognitive ability.

The invention relates to the technical field of breast milk oligosaccharide detection, and provides a breast milk oligosaccharide high-coverage analysis method based on liquid chromatography-high resolution mass spectrometry, which comprises the following steps: detecting breast milk oligosaccharide in a to-be-detected sample solution by using a UPLC-HRMS method, comparing fragment ions, retention time, primary parent ion accurate mass number and isotope distribution, and determining the breast milk oligosaccharide coverage degree of the to-be-detected sample solution according to the fragment ions, the retention time, the primary parent ion accurate mass number and the isotope distribution. The structure identification of the breast milk oligosaccharide in the breast milk sample is realized; chromatographic conditions in the UPLC-HRMS method are as follows: a 50mmol / L ammonium formate aqueous solution is taken as a mobile phase A, pure acetonitrile is taken as a mobile phase B, the elution mode is gradient elution, and the content of the mobile phase B is calculated by volume percent. According to the technical scheme, the problems of low coverage and low sensitivity during breast milk oligosaccharide detection and analysis in related technologies are solved.

The present application provides a micellar casein powder, a preparation method and system thereof and a food, wherein the calcium-phosphorus ratio of the micellar casein powder is (1-1.2):1. The micellar casein powder of the present application has a calcium-phosphorus ratio similar to breast milk, low mineral content, high solubility, high nutritional value and is suitable for large-scale production.

The present disclosure describes a breast milk and food storage solution that simplifies and reduces the number of items needed to pump, store and / or feed breastmilk to a baby.

1. Name of the Design Product: Breast Pump (5001). 2. Use of the Design Product: To assist lactating women in extracting breast milk. 3. Design Key Points of the Design Product: Lies in the shape. 4. Picture or Photograph that Best Illustrates the Design Key Points: Perspective View 1.

1. The name of this design product: Portable Breast Milk Cooling Cup (BW0203). 2. Purpose of this product: This product is used to keep beverages hot or cold. 3. The key design point of this appearance design product lies in the overall shape of the product. 4. The picture or photo that best illustrates the key points of the design: Design 1 three-dimensional diagram. 5. Designate Design 1 as the base design.