548 results about "Bifidobacterium longum" patented technology

According to the invention there is provided a strain of lactic acid bacteria of the species Bifidobacteria pseudolongum obtainable by isolation from resected and washed canine gastrointestinal tract having a probiotic activity in animals. Methods of use and compositions comprising the Bifidobacteria pseudolongum of the present invention are also provided.

The invention relates to a micro-ecological regulator, which belongs to the category of micro-ecological preparations. The product contains Bifidobacterium bifidum, Bifidobacterium longum, Bifidobacterium adolesentis, lactobacillus acidophilus, fructo-oligosaccharides, galacto-oligosaccharides, vitamins and the like. A concrete production process comprises the following steps: 1. bacterial strains are respectively or jointly subjected to liquid deep high-density cultu, so as to obtain fermentation liquid; 2. after the fermentation liquid is centrifuged, bacterial sludge is collected, added to protective agents and made into freeze-dried powder; 3. the freeze-dried powder is added to microcapsule materials and made into microcapsules through air suspension treatment; and 4. the microcapsules are mixed with oligosaccharides, vitamins and the like and then are made into a synbiotics pharmaceutical composition. By directly replenishing human intestines with Bifidobacterium and lactobacillus acidophilus, and by simultaneously providing prebiotics for ensuring that beneficial bacteria after entering intestines can be activated rapidly and proliferate, the product adjusts and improves intestinal micro-ecosystem, so as to achieve the aims of regulating organism immunity, delaying senility, inhibiting tumors, regulating blood lipid and improving intestines and stomach. A preparation method of the product can solve the technical problem that the prior probiotics medicine is difficult to keep the stability of probiotics at normal temperature and unstable under acidic conditions, and provides a pharmaceutical composition which can be stably stored at normal temperature.

The invention discloses bifidobacterium bifidum capable of remarkably relieving constipation and application thereof and belongs to the technical field of microorganisms. The bifidobacterium bifidum CGMCC NO.13632 can well tolerate simulative gastrointestinal fluid, can be well attached to colon cancer cells HT-29, and can remarkably increase the water content of excrement of constipation mice and shorten the first tarry stool time. On the aspect of increasing the small intestine driving rate, the bifidobacterium bifidum CGMCC NO.13632 is superior to cathartic phenolphthalein, a best effect is shown, secretion of gastrointestinal regulatory peptide relevant to constipation in serum is also adjusted while constipation pathological factors are remarkably improved, and the bifidobacterium bifidum does not have toxic and side effects of medicine for treating constipation, and is a first choice for preventing and treating constipation. The bifidobacterium bifidum CGMCC NO.13632 is used for preparing pharmaceutical compositions and fermented food for relieving constipation, and has very wide application prospects.

The invention discloses bifidobacterium longum and the application thereof and belongs to the technical field of biologics. The invention provides a bifidobacterium longum YS108R strain which has thecharacteristic of generating viscous exopolysaccharide, and has a remarkable improvement function on DSS (Dextran Sulfate Sodium) induced mouse colitis models. The strain has a relatively good capability of enduring simulated gastrointestinal fluids, is capable of remarkably reducing disease activity indexes of mice in the DSS induction period, and has an effective protection function on colon tissue. In addition, the bifidobacterium longum YS108R disclosed by the invention is separated from intestinal florae of healthy people, is free of toxic and/or side effects on human bodies, and has certain advantages when being compared with conventional medicine treatment. The strain can be used for preparing probiotic powder, fermented milk, and the like, and has wide market prospects.

The invention discloses bifidobacterium longum and applications thereof, and belongs to the technical field of microorganisms. The bifidobacterium longum is deposited in the China General Microbiological Culture Collection Center in Institute of Microbiology, Chinese Academy of Sciences at number 3, No.1 yard, Beichenxi road, Chaoyang district, Beijing on December 7, 2017, and the accession numberis CGMCC NO.15032. The bifidobacterium longum has good growth, acid production, and acid resistant properties, and high adhesive capacity, can significantly increase the water content of faeces and the pushing rate of small intestine of mice with constipation, shortens the first black stool evacuation time, relieves inflammation of colonic mucosas, and regulates contents of gastrointestinal peptides related to constipation in serum. A constipation relieving effect of the bifidobacterium longum is equivalent to that of bifidobacterium animalis BB12, but an effect of the bifidobacterium longumon the pushing rate of small intestine is superior to those of bifidobacterium animalis BB12 and phenolphthalein. Accordingly, the bifidobacterium longum strain CCFM760 can be widely applied in various foods or medicine matrixes.

Live strains of Lactococcus sp. HY 49, Lactobacillus casei HY 2782, and Bifidobacterium longum HY 8001 maintained in nutritious foods, such as yogurt, imbue them with prophylactic and/or therapeutic properties. Such foods are beneficial in the prevention and/or treatment of gastritis, duodenal and gastric ulcers caused by infection from Helicobacter pylori (also referred to as H. pylori). The properties of these bacteria are boosted by the addition of egg yolk containing antibodies specific to H. pylori antigen derived from "fractionated H. pylori".

The present invention discloses a special penaeus orientalis functional biological feed in the thickness marking period and the functional biological feed consists of the following components: import fish meal, shrimp meal, fermented peanut meal, fermented soybean meal, yeast lysates, cuttlefish powder, high gluten flour, calcium dihydrogen phosphate, soybean lecithin, fish oil, vitamin-mineral premixes, probiotics and functional additives; wherein the probiotics consist of Bacillus subtilis subsp., Candida utilis yeast and Bifidobacterium longum; the functional additives are made of natural astaxanthin, linolenic acid, fermented chlorella and fermented spirulina. The functional biological feed aims at the physical characteristics of high density, high nutrition and fast growth of penaeus orientalis seedlings in the thickness marking period, uses high-quality animal protein, contains high levels of unsaturated fatty acids and bio-fermentation raw materials, is rich in lecithin, has a reasonable balance ratio of calcium and phosphorus, and fortified vitamin nutrition, adds immunoenhancers, living beneficial bacteria and digestive enzymes, promotes the rapid growth, enhances disease resistance and improves survival rate of penaeus orientalis seedlings which have strong body constitution and tidy specifications, and lay a solid foundation for subsequent successful breeding.

The invention discloses a lactic acid bacteria composition capable of regulating intestinal flora functions and preparation method and application thereof. The active ingredients of the lactic acid bacteria composition capable of regulating intestinal flora functions are prepared from the following raw materials by weight: 20-40 parts of Lactobacillus acidophilus, 40-60 parts of Bifidobacterium longum, 20-60 parts of Lactobacillus rhamnosus, 30-60 parts of Streptococcus thermophilus and 35-75 parts of fructo-oligosaccharide. According to the lactic acid bacteria composition capable of regulating intestinal flora functions, lactic acid bacteria in the composition can reach a certain magnitude, and the raw materials are in reasonable compatibility, and have a good function of regulating intestinal flora. The lactic acid bacteria composition has good stability in a long time, and is suitable for the diabetics to eat.

The invention discloses a bifidobacterium longum microcapsule and a preparation method thereof. The core material is bifidobacterium longum BBMN68; the wall material comprises metaprotein and polysaccharide; the core material is mixed with the sterilized wall material; the freeze-drying bifidobacterium longum microcapsule is prepared by orifice-coagulating bath and vacuum freeze drying; the bifidobacterium amount of the microcapsule is 108 to 1011 CFU/g. After the microcapsule is stored at room temperature for 6 months, the amount of the bifidobacterium is still more than 108 CFU/g; major viable count in intestine can be realized after the freeze-drying microcapsule particles get through the stomach, and most of the bifidobacteriums are released in the intestine. The bifidobacterium microcapsule is processed by freeze drying so as to provide low-temperature, vacuum and dry environment for bifidobacterium BBMN68; thus, the microcapsule overcomes the shortcomings that bifidobacterium does not resist acid and oxidation, and is not easy to survive, and the like; moreover, the microcapsule has the advantages of long expiration date, good storage stability and enteric solubility.

The invention discloses a probiotic and prebiotic composition for forming lean body mass and application thereof, and relates to the field of biomedicine. The composition comprises probiotics such asbifidobacterium lactis, bifidobacterium longum, lactobacillus reuteri, lactobacillus rhamnosus, lactobacillus acidophilus, streptococcus thermophilus, bacillus coagulans and clostridium butyricum, anda prebiotic mixture is also added. By reasonably matching the components of the composition, the intestinal flora is effectively regulated, and the obesity is more efficiently and healthily relieved;for people with normal weight, the weight reduction effect is not obvious, but the body shape is more beautiful; meanwhile, the composition can effectively prevent hyperglycemia, hyperlipidemia and other diseases and improve the body immunity, is suitable for a wider range of people, and can be applied to food, pharmacy and healthy or natural product production.

The invention relates to probiotic solid beverage and a preparation method thereof. The probiotic solid beverage comprises the following raw materials in parts by weight: 24 to 70 parts of maltodextrin, 20 to 60 parts of inulin and 1 to 5 parts of probiotics, wherein the probiotics comprises lactobacillus salivarius, lactobacillus acidophilus, bacillus coagulans, lactobacillus rhamnosus, bifidobacterium bifidum, lactobacillus plantarum and bifidobacterium longum. The probiotic solid beverage provided by the invention has high living bacterium quantity and can reduce loss of the probiotics whenthe probiotics pass through the gastrointestinal tract and increase the survival rate; in addition, the probiotic solid beverage can promote intestinal colonization of the probiotics; moreover, through mutual promotion of the actions of various bacteria, the probiotic solid beverage can adjust intestines and stomach well, promote intestinal tract movement, relieve constipation and diarrhea, reduce serum cholesterol, reduce lactose intolerance, accumulate proteolytic enzyme, adjust nutrient absorption and adjust the immunologic function.

A composition composed of a Lactobacillus bacterium, Bifidobacterium longum, and xylooligosaccharide is provided for use in reducing uric acid levels in the blood and preventing or treating hyperuricemia or gout.

The invention relates to a health-care food, and particularly provides health-care probiotics powder for intestinal tracts. The health-care probiotics powder is prepared from the following raw materials in parts by weight: 2-15 parts of bifidobacterium longum, 5-18 parts of saliva bacterium lacticum, 5-18 parts of bifidobacterium bifidum, 5-20 parts of bifidobacterium lactis, 2-15 parts of streptococcus thermophilus, 5-15 parts of lactobacillus bulgaricus, 2-18 parts of lactobacillus plantarum, 3-18 parts of lactobacillus acidophilus, 3-12 parts of microcrystalline cellulose, 2-18 parts of dietary fibers, 4-18 parts of ferment powder, 2-8 parts of xylooligosaccharide, 2-9 parts of citric acid and 2-12 parts of sorbitol, wherein the ferment powder is prepared from the following raw materials of pineapples, tomatoes, lemons, blueberries, cyclodextrine and microzymes. The invention further provides a preparation method of the health-care probiotics powder for intestinal tracts. The growth and the propagation of harmful bacteria can be restrained, the immune competence of bodies can be strengthened, the squirm of the intestinal tracts can be accelerated, the situation that excrement and urine are discharged out of bodies as soon as possible is urged, the stimulation of harmful toxins to intestinal walls is reduced, intestinal flora is regulated, and the purpose of alleviating constipation for a long term can be achieved; and in addition, the blueberries are also added, so that the health-care probiotics powder can improve eyesight.

The invention relates to a probiotic composition, and discloses a probiotic composition beneficial for a glycolipid metabolic function and a preparation and application of the composition. The probiotic composition comprises some of the following nine probiotics: bifidobacterium longum, bifidobacterium breve, lactobacillus gasseri, lactobacillus rhamnosus, lactobacillus salivarius, lactobacillus crispatus, lactobacillus plantarum, lactobacillus fermentum and lactobacillus casei. Different strains in the probiotic composition cooperate with each other, so that the probiotic composition has thefunction of adjusting glycolipid metabolism, and has certain effect on serum total cholesterol, triglycerides, insulin beta-cell functions and diabetes mellitus improvement.

A probiotic composition used for livestock and poultry can overcome micro dysbiosis, decreased disease resistance and production performance of livestock and poultry, and the side effects like drug resistance and drug residue which are caused by using antibiotics and chemical drugs in a large amount for a long time in feed. The probiotic composition contains effective components with the following weight portions: 3 to 10 portions of Lactobacillus acidophilus, 2 to 6 portions of yeast, 1 to 8 portions of bacillus subtilis, 3 to 8 portions of Bifidobacterium longum, 2 to 5 portions of bacillus licheniformis, and 1 to 4 portions of aspergillus oryzae and vector. The weight ratio of probiotic to vector is 2:7, and the content of the active compositions are that: greater than or equal to 8 billion/g of Lactobacillus acidophilus, greater than or equal to 7 billion/g of yeast, greater than or equal to 9 billion/g of bacillus subtilis, greater than or equal to 9 billion/g of Bifidobacterium longum, greater than or equal to 6 billion/g of bacillus licheniformis and greater than or equal to 6 billion/g of aspergillus oryzae, respectively. The probiotic composition of the invention can reduce lead content in animal products, achieve the purpose of producing green and harmless animal products, promote growth and development of animal and increase animal digestibility to feed.

The invention belongs to the field of health-care products, and particularly relates to a probiotics and Chinese herbal medicine compound preparation with a hypoglycemic function. The preparation is formed by mixing the components in parts by weight as follows: 25-30 parts of dioscorea roots, 15-25 parts of pueraria roots, 20-30 parts of cinnamon, 20-40 parts of lycium berries and 30-40 parts of freeze-dried probiotics powder, wherein probiotics comprises bacteria in percentage by weight as follows: 40% of bifidobacterium adolescentis, 40% of bifidobacterium longum, 10% of lactobacillus plantarum and 10% of lactobacillus rhamnosus. The preparation has the hypoglycemic function.

The invention discloses compound probiotics capable of relieving ulcerative colitis, a preparation method and application thereof, and relates to the technical field of microorganisms. The compound probiotics are characterized by comprising Bifidobacterium longum BL21, Bifidobacterium animalis subsp.lactis BLa80 and Lactobacillus casei LC89. The preparation method comprises the following steps of: respectively preparing freeze-dried powder of the Bifidobacterium longum BL21, the Bifidobacterium animalis subsp.lactis BLa80 and the Lactobacillus casei LC89; and uniformly mixing the three freeze-dried powder in proportion to prepare the compound probiotics. The compound probiotics provided by the invention can prevent and/or treat ulcerative colitis, and have a great application prospect in preparation of products (such as solid beverages) for preventing and/or treating ulcerative colitis.

The invention discloses a probiotic composition for relieving anxiety or depression and an application thereof. The probiotic composition comprises prebiotics, a K-KLJ probiotic combination and functional substances. The K-KLJ probiotic composition contains at least one of lactobacillus plantarum, lactobacillus reuteri, lactobacillus casei, and lactobacillus helveticus, or also contains at least one of lactobacillus rhamnosus, lactobacillus acidophilus, bifidobacterium animalis and bifidobacterium longum. The probiotic composition of the present invention can significantly increase quantity ofbeneficial intestinal flora, improve intestinal discomfort, and reduce chronic inflammation, thereby reducing unhealthy emotion, and preventing emotional diseases such as depression and anxiety. Moreover, according to the invention, the combination of probiotic strains, the prebiotics, the probiotic strains and the functional substances have effect of significant synergistic enhancement.

The invention discloses a novel compound microbial agent used for sludge reduction treatment. The compound microbial agent consists of photosynthetic bacteria, lactic acid bacteria and saccharomycetes, and comprises bacillus subtilis, bifidobacterium animals, bifidobacterium bifidum, bifidobacterium longum, lactobacillus acidophilus, lactobacillus casei, lactobacillus delbrueckii, lactobacillus fermentium, lactobacillus plantarum, lactococcus lactis, rhodopseudomonas palustris, streptococcus thermophilus and saccharomyces cerevisiae which are 13 different microorganisms in total. The compound microbial agent can reduce BOD (biochemical oxygen demand), COD (chemical oxygen demand) and TSS (total suspended solids) to expected values, effectively reduces sludge deposit in a treatment plant, and reduces corrosion on equipment to lower maintenance cost; and besides, bacteria can decompose an organic compound and can generate byproducts beneficial to environment.

The invention discloses fruit and vegetable ferment freeze-dried powder and a preparation method thereof. The fruit and vegetable ferment freeze-dried powder has good health-care effects on intestines and stomachs. The preparation method of the fruit and vegetable ferment freeze-dried powder comprises the following steps of (1) preparing raw materials of the fruit and vegetable ferment freeze-dried powder; (2) after treatment of the raw materials, firstly, adding lactobacillus reuteri for fermentation, and performing anaerobic fermentation under the condition of 35-37 DEG C for 2-3 days, then lowering the temperature to 30-35 DEG C, adding saccharomyces cerevisiae for fermentation under the condition that the pH is 3.5-5.5 for 2-3 days, enabling filtered sterile air to be led, and finally, adding bifidobacterium longum for anaerobic fermentation for 2-3 days so as to obtain fermentation broth; and (3) filtering the fermentation broth, and performing vacuum freeze drying so as to obtain the fruit and vegetable ferment freeze-dried powder. According to the fruit and vegetable ferment freeze-dried powder and the preparation method thereof disclosed by the invention, various green pollution-free fruits, vegetables, yams, beans and wild herbs, having good health-care effects on intestines and stomachs are selected to be used as fermentation base materials, and through multistage fermentation and post-treatment, the fruit and vegetable ferment freeze-dried powder is obtained.

The invention relates to the use, in the manufacture of a medicament or a therapeutic nutritional composition for preventing or reducing inflammation in a mammal, of bifidobacterium longum ATCC BAA-999.

The invention relates to a biological preparation, and in particular to an anti-aging probiotic preparation and a preparation method thereof. The anti-aging probiotic preparation consists of effective doses of bifidobacterium longum BL21, lactobacillus plantarum Lp90 and adjuvants. The bifidobacterium longum BL21 is preserved in China General Microbiological Culture Collection Center with preservation number of CGMCC NO.10452; and the lactobacillus plantarum Lp90 is preserved in China General Microbiological Culture Collection Center with preservation number of CGMCC NO.10453. According to the anti-aging probiotic preparation and the preparation method provided by the invention, by regulating an intestinal flora, keeping intestinal flora balance and inhibiting the growth of harmful bacteria, body aging can be delayed.

The invention discloses a micro-ecological composition for improving constipation by targeting intestinal flora and a preparation of the micro-ecological composition. The micro-ecological compositioncomprises probiotics, prebiotics and medicinal and edible traditional Chinese medicines, wherein the probiotics are selected from at least one of bifidobacterium animalis, bifidobacterium adolescentis, bifidobacterium longum, bifidobacterium breve, lactobacillus rhamnosus, lactobacillus acidophilus, lactobacillus helveticus, lactobacillus plantarum, lactobacillus reuteri, lactobacillus paracasei and bacillus coagulans; the prebiotics are selected from at least one of stachyose, fructo-oligosaccharide, isomalto-oligosaccharide, galacto-oligosaccharide, inulin, resistant dextrin and xylooligosaccharide; and the medicinal and edible traditional Chinese medicines are selected from at least one of semen sesami nigri, semen cassiae, fructus cannabis, honey, semen lablab album, semen coicis, poria cocos and lotus leaves. The micro-ecological composition can effectively regulate intestinal tract micro-ecology in a targeted mode, and finally the purpose of improving constipation is achieved.

The invention discloses a complex probiotics solid drink. The product is prepared from 0.04g of anti-allergy complex bacterial powder, 1.76g of inulin and 0.2g of stachyose; each bag of the product contains 6 billion of bacterial powder, the complex bacterial powder includes lactobacillus reuteri, lactobacillus paracasei, bifidobacterium longum and bifidobacterium lactis, and the 6 billion of bacterial powder includes 1 billion of lactobacillus reuteri, 3 billion of lactobacillus paracasei, 1.5 billion of bifidobacterium longum and 0.5 billion bifidobacterium lactis. The complex probiotics solid drink has the beneficial effects of being suitable for any people, regulating immunologic balance, relieving allergy, giving consideration to both regulation of intestinal flora and relieving of diarrhea and constipation.

The invention belongs to the technical field of food and health care products, and particularly relates to a quintuplet probiotic composition for improving intestinal tracts. The quintuplet probioticcomposition comprises the following components in parts by weight: 60-65 parts of polyisomaltose, 25-30 parts of maltodextrin, 15-20 parts of erythritol, 10-12 parts of galactooligosaccharide and 11-25 parts of probiotic, wherein the probiotic comprises lactobacillus rhamnosus R0011, lactobacillus helveticus R0052, lactobacillus rhamnosus GG, animal bifidobacterium B94 and bifidobacterium longum R0175. At the same time, the invention provides a composite solid beverage prepared from the quintuplet probiotic composition. Through a scientific strain ratio, gastrointestinal tracts are promoted toabsorb an effective quantity of viable bacteria; intestinal florae are adjusted; uncomfortable symptoms of the gastrointestinal tracts, such as various uncomfortable symptoms of the gastrointestinaltracts after flora disequilibrium due to bacterial infection and antibiotic related diarrhea, are improved; an intestinal environment is adjusted, so that the immunity is boosted; an immunoreaction ofan allergic disease is adjusted fundamentally; a constitution environment of females can also be improved; and bacterial vaginitis is effectively prevented and treated.