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13 results about "Glucoraphanin" patented technology

Glucoraphanin is a glucosinolate found in broccoli, cauliflower, and mustard. Glucoraphanin is converted to sulforaphane by the enzyme myrosinase. In plants, sulforaphane deters insect predators and acts as a selective antibiotic. In humans, sulforaphane has been studied for its potential affects in neurodegenerative and cardiovascular diseases.

Freeze-dried broccoli processing method

The invention relates to the technical field of food processing, in particular to a freeze-dried broccoli processing method. The invention provides a freeze-dried broccoli processing method which comprises the following steps: taking cleaned broccoli, and cutting the broccoli into small flower types which are consistent in size, shape, thickness and height; carrying out instantaneous fixation by adopting steam, immediately soaking the broccoli subjected to fixation in ice water, fishing out the broccoli, and draining water; stacking the quick-frozen broccoli and the dry ice layer by layer; and after the temperature of the broccoli is reduced to-40 DEG C to-60 DEG C, performing vacuum freeze drying until the water content is less than or equal to 3% to obtain the dehydrated broccoli. According to the method, the loss of functional components such as glucoraphanin and polyphenol is reduced; formation of ice crystals is reduced, cell damage is reduced to the maximum extent, the content of functional components is effectively maintained, the color is close to that of fresh broccoli, and rehydration performance is good; the retention rates of functional components of glucoraphanin, flavone and vitamin C in broccoli all reach 98% or above.
Owner:ZHEJIANG UNIV OF SCI & TECH

Composition capable of efficiently releasing sulforaphane targeting NRF2 and application of composition

The present invention relates to a nutritional targeting composition which comprises a component 1 providing glucoraphanin, a component 2 providing myrosinase and magnesium stearate and which efficiently releases sulforaphane to activate NRF2 targets. The present invention also relates to the use of the composition in the preparation of products for preventing or treating diseases or conditions which can be prevented or treated by using sulforaphane.
Owner:SHENZHEN F&S BIO TECH CO LTD

Use of BoCBL or BoCGS1 in regulating the content of glucoraphanin in broccoli

The application discloses application of BoCBL or BoCGS1 in regulating content of glucoraphanin in broccoli and belongs to the field of genetic engineering. The application finds that overexpression of BoCBL or BoCGS1 in broccoli can significantly increase the content of glucoraphanin in broccoli, the content of GRA in the hairy root of the overexpression CBL and CGS1 is increased by 179% and 120% respectively, and the content of the above-ground part is increased by 146% and 30% respectively. Therefore, the two genes can be used for regulating the content of glucoraphanin in broccoli and cultivating a broccoli strain with high glucoraphanin content.
Owner:NORTHEAST FORESTRY UNIV

A liver-protecting composition, its preparation method, application and product

PendingCN122251464Alower levelStable structural integrityOrganic active ingredientsDigestive systemGlucoraphaninNutrition
The present application belongs to the field of nutritional composition and biological medicine technology, and particularly relates to a composition for protecting and preserving liver, a preparation method, application and product thereof. The composition of the present application is composed of extract of Silybum marianum, glucoraphanin and extract of Cynara scolymus. The composition of the present application can intervene the pathological process of liver injury from multiple dimensions such as antioxidation, anti-inflammation, regulation of lipid metabolism and repair of hepatocytes through synergistic effect of the three components, significantly reduces the levels of glutamic-pyruvic transaminase and glutamic-oxalacetic transaminase, reduces the accumulation of liver fat, improves the antioxidant capacity of the body, effectively prevents or improves alcoholic, chemical, non-alcoholic fatty and autoimmune liver injury, delays the progression of liver fibrosis, and comprehensively maintains the structural integrity and functional stability of the liver.
Owner:HEALTH & HAPPINESS H&H HONG KONG LTD +1

Composition capable of efficiently releasing sulforaphane targeting NRF2 and application of composition

The present invention relates to a nutritional targeting composition which comprises a component 1 providing glucoraphanin, a component 2 providing myrosinase and magnesium stearate and which efficiently releases sulforaphane to activate NRF2 targets. The present invention also relates to the use of the composition in the preparation of products for preventing or treating diseases or conditions which can be prevented or treated by using sulforaphane.
Owner:SHENZHEN F&S BIO TECH CO LTD

Lactobacillus plantarum ZUST49 and bacterial agent, and use thereof

The present disclosure discloses a Lactobacillus plantarum ZUST49 and a bacterial agent, and use thereof, and belongs to the technical field of microorganisms. An aspect of the present disclosure provides a Lactobacillus plantarum ZUST49 and a bacterial agent containing the Lactobacillus plantarum ZUST49, and another aspect provides use of the Lactobacillus plantarum ZUST49 and the bacterial agent containing the Lactobacillus plantarum ZUST49. The Lactobacillus plantarum ZUST49 of the present disclosure may convert glucoraphanin into sulforaphane, especially in a human or animal intestinal environment. After an enteric probiotic preparation prepared from the strain of the present disclosure is orally taken, the Lactobacillus plantarum ZUST49 may efficiently convert the glucoraphanin into the sulforaphane in an intestinal tract, which not only solves a problem that stability of the sulforaphane cannot be improved in the prior art, but also effectively exerts a probiotic effect.
Owner:ZHEJIANG UNIV OF SCI & TECH

Method for synergistically extracting glucoraphanin and endogenous myrosinase and extracted product

The invention relates to a glucoraphanin and endogenous myrosinase synergistic extraction method and an extraction product, and relates to the technical field of extraction of active ingredients in plants, broccoli seeds and an extraction solution containing an inhibitor are mixed, then high-temperature instantaneous extraction is conducted, an extraction feed liquid is obtained, and the inhibitor contains tea polyphenol and menthol with the mass ratio being (2-3): 1; filtering the extracted material liquid, and performing ultrafiltration on filtrate obtained by filtering to obtain permeate liquid and trapped liquid; the permeate is subjected to instantaneous sterilization treatment, concentration and spray drying, a component containing glucoraphanin is obtained, the trapped fluid is subjected to RO membrane concentration and freeze drying, and a component containing endogenous myrosinase is obtained. According to the extraction method disclosed by the invention, the enzyme and the glucoraphanin can be extracted at the same time under the condition that the enzyme activity is inhibited, and the obtained product is rich in glucoraphanin and also contains myrosinase with certain activity.
Owner:GUANGDONG QINGYUNSHAN PHARM CO LTD

Compositions and methods to increase production of isothiocyanates

Compositions and methods for converting at least one glucosinolate to an isothiocyanate using Bacillus subtilis 839, Bacillus subtilis CO4_4, Pediococcus pentosaceus M3_H01, and / or Pediococcus pentosaceus M2_H12, or active variants thereof, are provided. Conversion of glucosinolates, such as glucoraphanin, to isothiocyanates, such as sulforaphane, leads to the stimulation of the Nrf2 / Keap pathway and phase II enzymes, providing chemoprotective and anti-inflammatory effects. Accordingly, provided herein are compositions comprising Bacillus subtilis 839, Bacillus subtilis CO4_4, Pediococcus pentosaceus M3_H01, and / or Pediococcus pentosaceus M2_H12, or active variants thereof, for administration to subjects for increasing isothiocyanate (e.g., sulforaphane) production, increasing the expression of genes regulated by the Nrf2 transcription factor, including phase II enzymes, decreasing inflammation, and treating or preventing an inflammatory disorder or a cancer. The composition can comprise at least one glucosinolate or a plant, plant part or an extract thereof comprising glucosinolate(s).
Owner:CHURCH & DWIGHT CO INC

NRF2-targeted composition capable of efficiently releasing sulforaphane and application of NRF2-targeted composition

The invention relates to a nutrition targeting composition which comprises a component 1 for providing glucoraphanin, a component 2 for providing myrosinase, vitamin C and magnesium stearate and is capable of efficiently releasing sulforaphane and activating an NRF2 target spot. The invention also relates to the use of said composition for the preparation of a product for the prevention or treatment of diseases or conditions that can be prevented or treated with sulforaphane.
Owner:SHENZHEN F&S BIO TECH CO LTD

Sulforaphane supplement in gummy form

PendingUS20260083667A1Peptide/protein ingredientsPharmaceutical delivery mechanismGlucoraphaninSulforaphane
A sulforaphane supplement in gummy form, including an active ingredient composition comprising sulforaphane, glucoraphanin, and myrosinase. The supplement including a matrix structure in which sulforaphane, glucoraphanin, and myrosinase are disposed in pores and immobilized therein.
Owner:SENSORY SCOUT LLC

Skincare composition and process for creating sulforaphane

A skincare composition includes a substance having a predetermined amount of one or more cruciferous vegetables, the predetermined amount of the one or more cruciferous vegetables including stabilized glucoraphanin and active myrosinase in a stable state; exposing the substance to a liquid activator causes a chemical reaction between the stabilized glucoraphanin and the active myrosinase to create sulforaphane in an active product; and applying the activated product to a skin surface allows the sulforaphane to act upon the skin surface.
Owner:COPELAND AMBER +1

Skin care preparation containing broccoli seed extract as well as preparation method and application of skin care preparation

PendingCN121243002ACosmetic preparationsAntipyreticBiotechnologyGlucoraphanin
The invention relates to a skin care preparation containing broccoli seed extract and a preparation method and application, and belongs to the technical field of skin care product preparation, the skin care preparation comprises broccoli seed oil extracted from broccoli seeds, sulforaphane and glucoraphanin, the skin care preparation is a mixed nano-emulsion, the skin care preparation further comprises the following preparation raw materials: Olivem 1000, butanediol and ultrapure water. By selecting and optimizing the extraction solvent and the extraction conditions, the effect of extracting the broccoli seed oil, the sulforaphane and the glucoraphanin from the broccoli seeds at the same time is achieved, the yield of the broccoli seed oil and the yield of the glucoraphanin are increased, and the yield of the broccoli seed oil and the glucoraphanin is increased by compounding the three extracts. The skin care preparation with excellent anti-oxidation, melanin inhibition and anti-inflammatory effects is obtained.
Owner:INST OF ADVANCED TECH UNIV OF SCI & TECH OF CHINA +1

Method for improving sulforaphane content in fresh-cut broccoli by salicylic acid combined with ultrasonic treatment

PendingCN122498555ABiotechnologyGlucoraphanin
The application provides a method for improving sulforaphane content in fresh-cut broccoli by combining salicylic acid and ultrasonic treatment, and belongs to the technical field of food processing and postharvest preservation. The method unifies moderate fresh-cut injury, salicylic acid induction and ultrasonic cavitation treatment into a continuous process scheme, avoids quality deterioration caused by excessive cutting, promotes accumulation of glucoraphanin and improves contact efficiency of glucoraphanin and endogenous myrosinase, so that the generation level of sulforaphane is improved. The method is simple in steps, short in treatment time, controllable in cost, and suitable for processing of high-sulforaphane fresh-cut broccoli products.
Owner:HEBEI AGRICULTURAL UNIV.