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If you have chronic inflammation of the gastrointestinal tract, you could have IBD, which primarily includes: Ulcerative colitis: Inflammation is usually on the innermost lining of your large intestine (colon). Crohn’s disease: Inflammation can occur anywhere along the lining of your digestive tract.
Proteins for the treatment of epithelial barrier function disorders
The disclosure relates to therapeutic proteins and pharmaceutical compositions comprising said proteins, which have utility in treating various human diseases. In particular aspects, the disclosed therapeutic proteins are useful for treating human gastrointestinal inflammatory diseases and gastrointestinal conditions associated with decreased epithelial cell barrier function or integrity. Further, the disclosed therapeutic proteins are useful for treating human inflammatory bowel disease, including inter alia, Crohn's disease and ulcerative colitis.
Owner:GENEVIVE INC