66 results about "Intestinal contents" patented technology

The invention discloses a non-invasive intestinal flora fixed-point sampling and drug release device, and belongs to the technical field of micro-ecological diagnosis and treatment. The device comprises a shell, an internal storage bin, a medicine loading cavity and a channel switching mechanism. The shell adopts a capsule-shaped design, and an enteric coating is arranged on the surface of the shell, so that the function is started after the shell reaches a specified position of an intestinal tract. Through the internal ingenious mechanism linkage design, the device can firstly complete non-invasive fixed-point sampling of intestinal contents, and after the sampling action is completed, a drug release mechanism is automatically triggered, so that accurate drug delivery of the same part is realized. Cooperative operation of sampling and drug release in time sequence and space is achieved, and the problems of pain, disjunction of the diagnosis and treatment process, poor drug targeting and the like caused by traditional invasive operation are effectively solved. The device is flexible in structural design, has the advantages of being noninvasive, efficient, accurate in time sequence control and the like, and is suitable for integrated application of diagnosis and treatment of various digestive tract diseases such as inflammatory bowel disease management, micro-ecological regulation and the like.

The invention provides a preparation method of a Witzia ciliaris IOB502 microbial inoculum and an application of the Witzia ciliaris IOB502 microbial inoculum in the aspect of recovering intestinal motility, the Witzia ciliaris IOB502 microbial inoculum is prepared by adopting a method of carrying out low-oxygen stress staged fermentation on chickpeas by adopting the Witzia ciliaris IOB502, and the generation of vitamins B1 and B2 can be promoted. The microbial inoculum does not affect physiological development of important organs such as liver, spleen and small intestine of mice, can improve defecation symptoms of the mice with constipation, increase defecation times and water content of excrement, improve intestinal movement of the mice with constipation, promote smooth passage of intestinal contents, effectively improve colon injury of the mice with constipation, and improve the constipation rate of the mice with constipation. Comprising mucous membrane layer thinning and mucus secretion reduction.

The invention belongs to the field of microorganisms, and relates to lactobacillus paracasei. In particular discloses a lactobacillus paracasei strain HNGD-AL1, the taxonomic name is Lactobacillus paracasei, the lactobacillus paracasei strain HNGD-AL1 is preserved in China Center for Type Culture Collection on February 27, 2025, the preservation number is CCTCC M 2025303, and the preservation address is No. 299 on eight road in Wuchang District, Wuhan, Hubei. The method for degrading the sulfur-containing amino acid by adopting the lactobacillus paracasei is found for the first time, the effect of degrading 53.39% of the sulfur-containing amino acid can be achieved by culturing the probiotics in a fermentation culture medium for 24 hours, and the probiotics can be colonized in intestinal tracts and play a role in degrading the sulfur-containing amino acid in intestinal contents; the content of metabolite hydrogen sulfide of sulfur-containing amino acid in the intestinal tract is reduced by 60.92%, intestinal tract tissue damage, permeability and inflammatory response are reduced, and the purpose of improving ulcerative colitis is achieved. The preparation method has a wide application prospect in the aspects of preparation of low-sulfur-content amino acid foods and probiotic preparations for improving colitis.

The invention discloses lactobacillus paracasei CFCFC018, a microbial agent and application of the lactobacillus paracasei CFCFC018, and belongs to the technical field of microorganisms. The lactobacillus paracasei CFCFC018 is separated from intestinal contents of rural cats in half-farming and half-pastoral areas in Inner Mongolia, does not need genetic engineering modification, can highly express amino acids and neurotransmitters, can remarkably relieve mammary gland alveolar structure damage in mammary gland tissues of rats suffering from mastitis induced by staphylococcus aureus, and has the advantages of being high in safety and good in stability. The thickening of a mammary gland interacellular matrix layer is avoided, the infiltration number of neutrophils is reduced, the damage degree of mammary gland tissues is reduced, and a certain protection effect on the mammary gland tissues is achieved. The research also shows that the strain can reduce the abundance of harmful bacteria in excrement, improve intestinal inflammation and relieve edema of intestinal submucosa, which provides a new thought for preventing and treating mastitis by regulating intestinal microbiota.

The invention relates to the field of medical apparatus and instruments in rectum surgery, and particularly provides a novel multifunctional intestinal bypass device for rectum surgery, which comprises a hollow sleeve, a film sleeve, a decompression air bag sleeved outside the hollow sleeve, and an inflation channel, wherein after being inflated, the decompression air bag protrudes in a corrugated or threaded mode in the axial direction of the hollow sleeve, the protruding part makes contact with the intestinal wall to provide friction force, and a decompression gap is formed between the sunken part and the intestinal wall; according to the invention, intestinal contents are discharged from the hollow sleeve and the film sleeve, so that excrement or intestinal juice is prevented from being in contact with an anastomotic stoma, the infection risk of the anastomotic stoma is reduced, and the healing rate of the anastomotic stoma is accelerated; the thin film sleeve is soft and deformable, so that discomfort such as anus falling expansion, pain and tenesmus of a patient can be effectively reduced, and the comfort of the patient is improved; the decompression air bag is expanded through the inflation channel, the hollow sleeve is positioned, meanwhile, blood supply of the intestinal wall is protected, and the reliable effect of replacing preventive fistulization is achieved.

The present invention belongs to the technical field of fermented feed and relates to a method for preparing fermented feed by using bovine intestinal lactobacilli. The method specifically comprises the following steps: step 1, mixing intestinal contents with pre-sterilized physiological saline, filtering and adding amino acids; step 2, adjusting the pH of the intestinal solution, anaerobic culturing, and then mixing with an adsorption carrier to obtain a solidified bacterial agent; step 3, mixing the feed, the solidified bacterial agent and the filtrate of step 2, and fermenting in three stages; step 4, drying after the fermentation is completed to obtain the fermented feed. The present invention systematically solves the core problems of existing fermented feed, such as poor strain adaptability, low fermentation efficiency, easy contamination and high storage cost, by synergistically acting through multiple technologies such as specific strain screening, multi-stage dynamic control process and composite antibacterial.

The utility model discloses a neonatal closed enemator, and particularly relates to the technical field of medical auxiliary instruments, the neonatal closed enemator comprises an enema mechanism, the upper side of the rear end of the enema mechanism is fixedly connected with a flushing mechanism, and the lower side of the rear end of the enema mechanism is fixedly connected with a waste liquid collecting mechanism; the upper end of the inner surface of the flushing mechanism is fixedly connected with a temperature monitoring mechanism, and the rear ends of the flushing mechanism and the waste liquid collecting mechanism are jointly connected with a supporting mechanism in a clamped mode. When the neonatal closed enemator is used, a flushing bag is used for storing flushing fluid, the flushing fluid can be injected into a system through a flushing pipe and an adjusting valve seat, and a drainage anal tube is used for conveying the flushing fluid to the intestinal tract of the neonatal from the flushing bag and the flushing pipe. Meanwhile, intestinal contents are drained to the collecting tube and the waste liquid bag, liquid and excrement discharged from the drainage anal tube are collected and stored, and the temperature monitor monitors the temperature of enema liquid in the flushing bag through the monitoring probe.

The invention belongs to the technical field of soil remediation, and relates to a method for remediating norfloxacin contaminated soil by using earthworm intestinal contents, which comprises the following steps: inducing earthworms to empty the intestinal contents on quartz sand by illumination, extracting by using a phosphate buffer solution, activating nutrient solution and treating by using a modifier to obtain high-activity modified earthworm intestinal contents, and granulating with activated carbon, organic acid and mineral materials according to a specific ratio, and embedding and curing to prepare the repairing agent. After the remediation agent is applied to the contaminated soil, efficient decomposition of norfloxacin and synchronous restoration of the ecological function of the soil are achieved through the degradation effect of earthworm intestinal microorganisms, the adsorption effect of activated carbon, the complex reaction of organic acid and physical regulation and control of mineral materials. The method creatively utilizes natural microbial communities in the intestinal tract of the earthworm, has the advantages of thorough degradation, environmental compatibility, low cost, simplicity and convenience in operation and the like, and effectively overcomes the problems of chemical residues, poor microbial adaptability, long repair period and the like in a traditional repair method.

The invention discloses an intestinal microneedle anastomosis stent with an antibacterial function and a preparation method and application thereof, which can effectively and physically isolate an anastomotic stoma from intestinal contents and provide a relatively clean local environment for healing of the anastomotic stoma. The microneedle anastomotic stent is fixed at the anastomotic stoma, so that the tension at the anastomotic stoma can be further reduced, and the occurrence of anastomotic stoma leakage caused by overlarge tension is avoided; the microneedle layer on the surface of the stent can realize in-situ long-acting slow release of berberine hydrochloride (BBH) on the superficial layer of an anastomotic stoma, so that the drug utilization rate of the BBH is improved, the initial inflammation of the anastomotic stoma can be effectively reduced, and the anastomotic stoma can be regulated and controlled to be better healed. Animal experiment results prove that the implantation of the microneedle anastomosis stent can effectively reduce inflammatory cell infiltration of local tissues, reduce anastomotic stoma arrangement and regulate the anastomotic stoma to heal smoothly.

The present invention discloses an intestinal flow field modeling method and device based on bidirectional fluid-solid coupling. The method comprises: S1, collecting intestinal multimodal data; wherein the multimodal data includes geometric parameters, motion characteristics, content statistics and wall stress and strain data of the intestine; S2, reconstructing a three-dimensional geometric model of the human intestine; S3, preprocessing the established intestinal geometric model by format conversion and simplification and modification; S4, dividing the preprocessed model into a fluid domain and a solid domain, and establishing a bidirectional fluid-solid coupling model architecture; S5, performing fluid domain simulation settings: simulating multiphase flow contents and setting a fluid simulation model; S6, performing solid domain simulation settings: setting intestinal wall material parameters and simulating intestinal movement; S7, achieving bidirectional fluid-solid coupling and simulating the intestinal flow field. The method takes into account the bidirectional interaction between the intestinal wall solid domain and the intestinal content fluid domain, achieving more accurate intestinal flow field simulation.

This utility model discloses a protective anal tube for rectal anastomosis after surgery, relating to the field of medical device technology. It solves the initial problem of the need to develop a protective anal tube for rectal anastomosis after surgery that has three-dimensional isolation, facilitates negative pressure drainage, and has a biological barrier function. The utility model includes a tube body with two support members on it for supporting the intestine. Both support members are capable of mechanical deformation, and the contact surfaces between the two support members and the intestine are annular, which can support both sides of the intestinal anastomosis. Thus, a cavity is formed between the two support members and the anastomotic segment of the intestine. The purpose is that the two support members form a physical barrier through the annular contact surfaces, completely preventing the leakage of intestinal contents into the anastomotic area, avoiding contamination of the wound by feces and digestive juices, maintaining a moist environment, and promoting the migration of epithelial cells and the growth of granulation tissue.

The invention discloses an auxiliary device for jejunostomy nursing. The auxiliary device comprises an embedded air bag, a transition section and an outer side fixing disc. One end of the transition section is fixedly connected with the embedded air bag, and the other end of the transition section is fixedly connected with the outer side fixing disc; the embedded air bag is of an internally hollow inflatable air bag structure; the device can be embedded into the stoma of a patient to communicate the intestinal tract with the outside, the device can be expanded by adding gas or liquid so as to firmly fix the device and open the enteric cavity at the same time, and the device can also lift the opening of the stoma and turn intestinal contents, so that the nursing operation of the stoma is facilitated; and an ostomy bag can be better adhered, so that the skin of a patient is protected, and the risks of intestinal fistula and anastomotic fistula are reduced.

The invention provides pediococcus pentosaceus Su and application thereof, and belongs to the technical field of microorganisms. According to the invention, intestinal contents of horses and donkeys are screened to obtain a strain, the strain is identified as pediococcus pentosaceus, and the strain is mixed with lactobacillus plantarum to obtain the microbial inoculum. The microbial agent obtained by the invention can be used as an additive to improve the lactation yield of postpartum female donkeys and the nutritional quality of breast milk, increase the content of fat and improve the immunocompetence of donkey foals; the microbial inoculum can serve as a leavening agent to be fermented with motherwort, the obtained fermented motherwort serves as an additive, the optimized female donkey feed is obtained by optimizing a feed formula, the feed is used for feeding female donkeys, and the action effect of the microbial inoculum fermented motherwort in animal bodies is preliminarily understood.

The invention relates to the technical field of medical instruments, in particular to an intestinal obstruction catheter anti-reflux drainage device. The device comprises a three-way connector, a first drainage catheter communicated with a port in one end of the three-way connector, a spiral drainage tube communicated with a port in one end of the three-way connector, a one-way valve communicated with a port in one end of the three-way connector and a multi-cavity collection bag communicated with the spiral drainage tube. A plurality of elastic valves are arranged on the inner tube wall of the first drainage catheter in the circumferential direction of the first drainage catheter, each valve is provided with a pair of side edges and a lower edge, and the lower edges of the valves are fixedly connected with the inner wall of the first drainage catheter. According to the intestinal obstruction catheter anti-reflux drainage device, the problems that in existing intestinal obstruction drainage, intestinal contents in a drainage tube are prone to reflux, and the reflux solving operation is tedious are solved.

The invention discloses a closed enema system and an application method thereof, and belongs to the field of medical instruments, and the closed enema system comprises a perfusion pipeline used for being connected with a perfusion device for conveying enema liquid; the liquid discharging pipeline is used for being connected with a liquid discharging device for sucking intestinal contents; the outer wall of the drainage pipeline is sleeved with a turbidity sensor which is used for monitoring the turbidity of drainage liquid in real time; the filling pipeline and the liquid discharging pipeline are respectively communicated with the confluence pipeline; the controller is electrically connected with the turbidity sensor, the filling device and the liquid discharging device respectively; the controller is configured to receive monitoring data of the turbidity sensor in a liquid discharge stage and determine whether to start a next lavage cycle or not according to a comparison result of the data and a preset threshold value; and meanwhile, the filling device and the liquid discharging device are controlled to operate in a time-sharing manner. By means of the arrangement, preoperative clysis operation can be efficiently and rapidly completed in a patient-friendly mode.

The invention discloses a tunchang pig fat deposition related gene and microbial marker screening method and application, the method comprises the following steps: collecting fresh liver tissues and colon intestinal contents of high / low backfat thickness tunchang pigs, respectively carrying out liver transcriptome sequencing and intestinal microbial sequencing, and finding that the expression of CYP7A1 gene in the backfat pigs is obviously reduced, and the expression of CYP7A1 gene in the backfat pigs is obviously reduced; the gene is determined to be an important gene influencing the thickness of the Tonchang pig backfat by combining related analysis; the abundance of the Desulfovibrio flora in the intestinal tract of the high-backfat pig is obviously increased, and the Desulfovibrio flora is in obvious positive correlation with butyric acid. The invention discloses the effect of the CYP7A1 gene and Desulfovibrio flora abundance in regulating and controlling the fat deposition of the Trenchang pigs for the first time, provides candidate genes for molecular marker-assisted breeding of local pigs, and also provides a new idea for regulating and improving the fat deposition of the Trenchang pigs through microorganisms.

To provide an apparatus for treating a patient suffering from a disorder related to the passageway of the patient's intestines, such as constipation or incontinence.SOLUTION: An apparatus for treatment includes a pump to be implanted in a patient, where the pump is operable on at least one selected portion of the intestines to pump intestinal contents through the passageway of the intestines. The pump includes a constriction device adapted to alternately constrict the selected portion to at least substantially reduce the volume of the passageway of the intestines along the selected portion and release the selected portion to increase the volume of the passageway of the intestines along the selected portion, so that the intestinal contents are displaced through the passageway of the intestines.SELECTED DRAWING: Figure 2A

The present application provides a composition with satiety and weight control and anti-aging, and a preparation method and application thereof. The composition comprises the following raw materials by weight: polysaccharide 11-13 parts, fiber powder 20-25 parts, highland barley powder 12-18 parts, compound powder 18-23 parts, pectin 4-8 parts, ganoderma lucidum powder 6-9 parts, and compound protein 8-12 parts, and relates to the technical field of satiety and weight control and anti-aging compositions. The composition can form an effect of hindering nutrient absorption or prolonging gastric emptying, increase the volume of intestinal contents to achieve satiety, thereby achieving the functions of well controlling weight gain and reducing body weight. In addition, the composition can activate the body's antioxidant enzyme system, improve the activity of superoxide dismutase (SOD), and reduce the content of malondialdehyde (MDA), thereby delaying cell aging and achieving the anti-aging effect.

The application discloses an intestinal micro-needle anastomosis stent with an antibacterial function and a preparation method and application thereof, which can effectively physically isolate an anastomotic stoma from intestinal contents, provides a relatively clean local environment for healing of the anastomotic stoma, and further reduces tension at the anastomotic stoma by fixing the micro-needle anastomosis stent at the anastomotic stoma, so that anastomotic leakage caused by excessive tension is avoided; a micro-needle layer on a surface of the stent can realize in-situ long-acting slow release of berberine hydrochloride (BBH) on a superficial layer of the anastomotic stoma, so that drug utilization of the BBH is improved, and occurrence of initial inflammation of the anastomotic stoma is effectively reduced, and healing of the anastomotic stoma is better regulated. Animal experiment results prove that implantation of the micro-needle anastomosis stent can effectively reduce inflammatory cell infiltration of local tissues, reduce anastomotic arrangement, and regulate smooth healing of the anastomotic stoma.

The application discloses a method for improving the anti-cellular fibrosis of intestinal flora based on polysaccharides, and the steps of the method include: preparing Yunnan rhizoma polygonati mutant polysaccharide PKVP-1; and placing the Yunnan rhizoma polygonati mutant polysaccharide PKVP-1 in an intestinal environment to improve the anti-cellular fibrosis of intestinal flora. The steps of an experimental method for improving the anti-cellular fibrosis of intestinal flora based on polysaccharides include: selecting experimental animals and performing random grouping, and then performing drug administration; collecting the intestinal contents and kidney tissues of the experimental animals; taking the kidney tissues of the experimental animals to prepare paraffin sections for trichrome staining, and evaluating the inflammation degree of the kidney tissues according to the inflammatory cell infiltration; performing sequencing; detecting metabolites and obtaining a conclusion according to metabolite analysis. The method for improving the anti-cellular fibrosis of intestinal flora based on polysaccharides provided by the application improves the anti-cellular fibrosis ability of intestinal flora by placing the mutant polysaccharide in the intestinal environment of the experimental animals.

The present application relates to a kind of reagent and nanozyme immunochromatography test strip for detecting porcine rotavirus and its application, belong to biotechnology field, the present application is aimed at solving the technical problem of low sensitivity and poor specificity of existing porcine rotavirus detection method, its technical scheme main points are in containing capture antibody and detection antibody, the capture antibody is monoclonal antibody one, and the detection antibody is monoclonal antibody two, vice versa;Wherein the heavy chain variable region of monoclonal antibody one includes the sequence shown in SEQ ID NO:1, and the light chain variable region includes the sequence shown in SEQ ID NO:2;The heavy chain variable region of monoclonal antibody two includes the sequence shown in SEQ ID NO:5, and the light chain variable region includes the sequence shown in SEQ ID NO:6.The reagent can be used for preparing nanozyme immunochromatography test strip, realize the high sensitivity, high specificity detection of porcine rotavirus, suitable for the rapid detection of pig anal swab, feces or intestinal contents sample.

The utility model discloses a balloon catheter with a flushing structure. The balloon catheter solves the problem that an anastomotic stoma cannot be flushed in the prior art. The device comprises a blocker fixed at the front end of an anastomotic stoma, a catheter which is arranged in the blocker and is used for discharging intestinal contents, a balloon which is arranged on the outer wall of the catheter and is sealed with the inner wall of the blocker after being expanded, and a medium conveying mechanism which is connected with the catheter, is communicated with the balloon through the catheter and is used for conveying a medium, and the flushing mechanism is connected with the catheter and flushes the intestinal anastomotic stoma through the catheter. When suppuration occurs in the anastomotic stoma or intestinal secretions exist in the anastomotic stoma, the flushing mechanism sprays the flushing medium to the anastomotic stoma through the catheter, so that the anastomotic stoma is flushed, and intestinal suppuration or intestinal secretions are prevented from being attached to the anastomotic stoma to affect healing of the anastomotic stoma.

The application provides a stoma irrigation device, belonging to the field of stoma irrigation, and used for solving the problem of limited physical stimulation to the intestinal tract during stoma irrigation operation; the device comprises an insertion unit, a first liquid injection unit and a second liquid injection unit; the insertion unit comprises a first expansion piece, a second expansion piece and a flow rate adjusting piece arranged in sequence along an insertion direction; the first expansion piece is arranged, and the first liquid injection unit is used to inject gas or liquid into the first expansion piece, so that the first expansion piece is expanded, thereby fixing the insertion unit in the intestinal tract and avoiding leakage of the irrigation liquid; the second liquid injection unit is used to inject the irrigation liquid into the second expansion piece, so that the second expansion piece is expanded to actively induce intestinal peristalsis, change the traditional passive flushing mode, make the intestinal contents more easily softened and removed by peristalsis, shorten the cleaning time and improve the cleanliness; and the irrigation liquid enters the intestinal tract at a slow speed after being adjusted by the flow rate adjusting piece, so that the intestinal mucosa is protected and the discomfort of the patient is reduced.

The cancerous intestinal obstruction intervention device comprises a main drainage tube, a water bag and a body surface fixing mechanism are arranged on the main drainage tube, the water bag is arranged at the end, intervened into a patient, of the main drainage tube, and the body surface fixing mechanism is used for being matched with the water bag to fix the main drainage tube; the water bag is communicated with a plurality of jet flow mechanisms used for dredging intestinal contents based on contraction pressure of the water bag, self-adaptive switching mechanisms are arranged in the jet flow mechanisms, and the self-adaptive switching mechanisms are used for opening and closing the jet flow mechanisms based on pressure changes in the main drainage tube and switching the jet flow direction based on the pressure direction until the jet flow direction points to the blocking position. According to the scheme, the probability that the catheter is blocked can be reduced, and the smoothness of enteric cavity decompression is improved.

The present invention relates to the technical field of medical devices, and discloses a device for extracting and processing anaerobic bacteria from micro-aerobic intestinal contents, comprising a cabinet, the interior of which is hollow, an operating table provided on the top of the cabinet, a cavity provided at the bottom inside the operating table, and control structures provided on the front and back of the operating table. The device for extracting and processing anaerobic bacteria from micro-aerobic intestinal contents provided by the present invention has a control structure and an air-drying structure, both of which are started by a scraper, which is started by a motor control and then scrapes dirt from the surface of the operating table to one side. While scraping, the control structure also drives a flap to open, allowing dirt to fall onto the baffle. As the scraper moves backward, the flap rotates and closes, and the baffle is opened to allow dirt to fall into a collection box. The setting of the double opening and closing doors can ensure that the gas environment in the sealed box is not destroyed, thereby increasing detection accuracy.

This invention provides a postoperative fistula prevention device for the intestine, comprising a fistula prevention membrane assembly and a degradable proximal ring mechanism. The fistula prevention membrane assembly includes a thin film tube and a first placement cavity. The first placement cavity is located at one end of the thin film tube and is formed by flipping one end of the thin film tube. The degradable proximal ring mechanism is provided inside the first placement cavity. A distal support ring is fixedly connected to the end of the thin film tube away from the first placement cavity. This invention uses the degradable proximal ring mechanism in conjunction with the thin film tube to fix it to the intestinal tract by suturing. Then, the distal support ring is moved to drive the thin film tube to completely cover the anastomosis, and the distal support ring supports the thin film tube to isolate the intestinal contents from contact with the anastomosis, thus fully protecting the anastomosis. Furthermore, the entire internal structure of the fistula prevention device is a smooth channel, reducing the resistance of the intestinal contents and effectively reducing the risk of premature dislodgement.

The utility model relates to the technical field of medical instruments, in particular to an ileum fistulization bypass catheter device. The ileum fistulization bypass catheter device comprises a first catheter body, the front end of the first catheter body is of an open structure, a plurality of first through holes are formed in the side portion of the first catheter body, and an air bag assembly is arranged on the rear section of each first through hole; a connecting port is formed in the tube tail of the first tube body, and a drainage bag is detachably connected to the outer side of the connecting port; a first branch tube communicated with the air bag assembly is arranged on one side of the tube tail of the first tube body, and an air injection valve used for injecting air into the air bag assembly or exhausting air from the air bag assembly is installed on the first branch tube, so that the function of cutting off an enteric cavity (namely air bag intestinal obstruction) is achieved, intestinal contents can be transferred through a catheter, and the risk of leakage of an anastomotic stoma is reduced. The nursing bed is easy to operate, convenient to nurse and easy to accept by patients and family members, and pain caused by treatment of the patients is greatly reduced.

The invention relates to the technical field of medical apparatuses and instruments, in particular to an internal flow turning degradable ring latex sleeve for preventing anastomotic fistula after a low rectal cancer operation. Due to the special anatomical position of a low rectal cancer operation, the occurrence rate of postoperative anastomotic fistula is high, and prophylactic stoma can effectively reduce the occurrence rate of anastomotic fistula, but secondary operation is needed for stoma reduction. Therefore, a medical instrument which is safe, effective, easy and convenient to operate and capable of reducing rectal cancer postoperative anastomotic fistula from the physiological level needs to be researched and developed. Through the unique structural design and working principle of the degradable ring latex sleeve, internal turning of intestinal contents is achieved within a period of time after an operation, pressure and pollution at an anastomotic stoma are reduced, meanwhile, by means of the characteristics of degradable materials, secondary taking-out operation is avoided, and the degradable ring latex sleeve is soft in texture, can adapt to the contraction and closing state of muscles near the anorectal ring, and has a good application prospect. Healing of the anastomotic stoma is promoted, and the occurrence risk of anastomotic fistula is reduced.

The application discloses a system for predicting the occurrence time of the peak value of the non-esterified fatty acid concentration in the blood of a dairy cow after delivery, and belongs to the technical field of healthy breeding of dairy cows. The system takes the genus level relative abundance of five marker microorganisms in the intestinal contents of a dairy cow one week before delivery as input data, calculates a score through a preset discriminant model, and judges whether the peak value of the blood free fatty acid concentration after delivery occurs on the day of calving according to a set threshold. The overall prediction accuracy of the discriminant model reaches 90%, the prediction accuracy for dairy cows with a peak on the day of calving reaches 75%, the system is simple to operate and stable in performance, can realize pre-delivery early warning of high health risks of peripartum dairy cows, provides technical support for taking preventive measures in advance, improving the postpartum health status and lactation level of dairy cows, and has important practical application value and economic significance.