Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

40 results about "Intestinal contents" patented technology

The consistency of the intestinal contents changes gradually as the contents travel through the small intestine. In the duodenum, food is diluted with pancreatic enzymes and bile, which decrease stomach acidity.

Noninvasive intestinal flora fixed-point sampling and drug release device

The invention discloses a non-invasive intestinal flora fixed-point sampling and drug release device, and belongs to the technical field of micro-ecological diagnosis and treatment. The device comprises a shell, an internal storage bin, a medicine loading cavity and a channel switching mechanism. The shell adopts a capsule-shaped design, and an enteric coating is arranged on the surface of the shell, so that the function is started after the shell reaches a specified position of an intestinal tract. Through the internal ingenious mechanism linkage design, the device can firstly complete non-invasive fixed-point sampling of intestinal contents, and after the sampling action is completed, a drug release mechanism is automatically triggered, so that accurate drug delivery of the same part is realized. Cooperative operation of sampling and drug release in time sequence and space is achieved, and the problems of pain, disjunction of the diagnosis and treatment process, poor drug targeting and the like caused by traditional invasive operation are effectively solved. The device is flexible in structural design, has the advantages of being noninvasive, efficient, accurate in time sequence control and the like, and is suitable for integrated application of diagnosis and treatment of various digestive tract diseases such as inflammatory bowel disease management, micro-ecological regulation and the like.
Owner:CHENGDU MILITARY GENERAL HOSPITAL OF PLA

Preparation method of Witzia coagulans IOB502 microbial inoculum and application of Witzia coagulans IOB502 microbial inoculum in recovery of intestinal motility

The invention provides a preparation method of a Witzia ciliaris IOB502 microbial inoculum and an application of the Witzia ciliaris IOB502 microbial inoculum in the aspect of recovering intestinal motility, the Witzia ciliaris IOB502 microbial inoculum is prepared by adopting a method of carrying out low-oxygen stress staged fermentation on chickpeas by adopting the Witzia ciliaris IOB502, and the generation of vitamins B1 and B2 can be promoted. The microbial inoculum does not affect physiological development of important organs such as liver, spleen and small intestine of mice, can improve defecation symptoms of the mice with constipation, increase defecation times and water content of excrement, improve intestinal movement of the mice with constipation, promote smooth passage of intestinal contents, effectively improve colon injury of the mice with constipation, and improve the constipation rate of the mice with constipation. Comprising mucous membrane layer thinning and mucus secretion reduction.
Owner:TIANJIN MEDICAL UNIVERSITY GENERAL HOSPITAL +1

Novel multifunctional intestinal bypass device for rectum operation

The invention relates to the field of medical apparatus and instruments in rectum surgery, and particularly provides a novel multifunctional intestinal bypass device for rectum surgery, which comprises a hollow sleeve, a film sleeve, a decompression air bag sleeved outside the hollow sleeve, and an inflation channel, wherein after being inflated, the decompression air bag protrudes in a corrugated or threaded mode in the axial direction of the hollow sleeve, the protruding part makes contact with the intestinal wall to provide friction force, and a decompression gap is formed between the sunken part and the intestinal wall; according to the invention, intestinal contents are discharged from the hollow sleeve and the film sleeve, so that excrement or intestinal juice is prevented from being in contact with an anastomotic stoma, the infection risk of the anastomotic stoma is reduced, and the healing rate of the anastomotic stoma is accelerated; the thin film sleeve is soft and deformable, so that discomfort such as anus falling expansion, pain and tenesmus of a patient can be effectively reduced, and the comfort of the patient is improved; the decompression air bag is expanded through the inflation channel, the hollow sleeve is positioned, meanwhile, blood supply of the intestinal wall is protected, and the reliable effect of replacing preventive fistulization is achieved.
Owner:SICHUAN CANCER HOSPITAL

Closed enemator for neonates

The utility model discloses a neonatal closed enemator, and particularly relates to the technical field of medical auxiliary instruments, the neonatal closed enemator comprises an enema mechanism, the upper side of the rear end of the enema mechanism is fixedly connected with a flushing mechanism, and the lower side of the rear end of the enema mechanism is fixedly connected with a waste liquid collecting mechanism; the upper end of the inner surface of the flushing mechanism is fixedly connected with a temperature monitoring mechanism, and the rear ends of the flushing mechanism and the waste liquid collecting mechanism are jointly connected with a supporting mechanism in a clamped mode. When the neonatal closed enemator is used, a flushing bag is used for storing flushing fluid, the flushing fluid can be injected into a system through a flushing pipe and an adjusting valve seat, and a drainage anal tube is used for conveying the flushing fluid to the intestinal tract of the neonatal from the flushing bag and the flushing pipe. Meanwhile, intestinal contents are drained to the collecting tube and the waste liquid bag, liquid and excrement discharged from the drainage anal tube are collected and stored, and the temperature monitor monitors the temperature of enema liquid in the flushing bag through the monitoring probe.
Owner:昆明市儿童医院(云南省儿童医院)

Method for repairing norfloxacin contaminated soil by using earthworm intestinal contents

The invention belongs to the technical field of soil remediation, and relates to a method for remediating norfloxacin contaminated soil by using earthworm intestinal contents, which comprises the following steps: inducing earthworms to empty the intestinal contents on quartz sand by illumination, extracting by using a phosphate buffer solution, activating nutrient solution and treating by using a modifier to obtain high-activity modified earthworm intestinal contents, and granulating with activated carbon, organic acid and mineral materials according to a specific ratio, and embedding and curing to prepare the repairing agent. After the remediation agent is applied to the contaminated soil, efficient decomposition of norfloxacin and synchronous restoration of the ecological function of the soil are achieved through the degradation effect of earthworm intestinal microorganisms, the adsorption effect of activated carbon, the complex reaction of organic acid and physical regulation and control of mineral materials. The method creatively utilizes natural microbial communities in the intestinal tract of the earthworm, has the advantages of thorough degradation, environmental compatibility, low cost, simplicity and convenience in operation and the like, and effectively overcomes the problems of chemical residues, poor microbial adaptability, long repair period and the like in a traditional repair method.
Owner:ZHEJIANG FORESTRY UNIVERSITY +1

Intestinal microneedle anastomosis stent with antibacterial function as well as preparation method and application of intestinal microneedle anastomosis stent

ActiveCN121401509ASurgeryCoatingsBerberine hydrochlorideAnti bacterial
The invention discloses an intestinal microneedle anastomosis stent with an antibacterial function and a preparation method and application thereof, which can effectively and physically isolate an anastomotic stoma from intestinal contents and provide a relatively clean local environment for healing of the anastomotic stoma. The microneedle anastomotic stent is fixed at the anastomotic stoma, so that the tension at the anastomotic stoma can be further reduced, and the occurrence of anastomotic stoma leakage caused by overlarge tension is avoided; the microneedle layer on the surface of the stent can realize in-situ long-acting slow release of berberine hydrochloride (BBH) on the superficial layer of an anastomotic stoma, so that the drug utilization rate of the BBH is improved, the initial inflammation of the anastomotic stoma can be effectively reduced, and the anastomotic stoma can be regulated and controlled to be better healed. Animal experiment results prove that the implantation of the microneedle anastomosis stent can effectively reduce inflammatory cell infiltration of local tissues, reduce anastomotic stoma arrangement and regulate the anastomotic stoma to heal smoothly.
Owner:WENZHOU INST UNIV OF CHINESE ACAD OF SCI

An anastomosis protection anal canal after rectal surgery

ActiveCN224331108UColostomyRectal surgeryFeces
This utility model discloses a protective anal tube for rectal anastomosis after surgery, relating to the field of medical device technology. It solves the initial problem of the need to develop a protective anal tube for rectal anastomosis after surgery that has three-dimensional isolation, facilitates negative pressure drainage, and has a biological barrier function. The utility model includes a tube body with two support members on it for supporting the intestine. Both support members are capable of mechanical deformation, and the contact surfaces between the two support members and the intestine are annular, which can support both sides of the intestinal anastomosis. Thus, a cavity is formed between the two support members and the anastomotic segment of the intestine. The purpose is that the two support members form a physical barrier through the annular contact surfaces, completely preventing the leakage of intestinal contents into the anastomotic area, avoiding contamination of the wound by feces and digestive juices, maintaining a moist environment, and promoting the migration of epithelial cells and the growth of granulation tissue.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Closed enema system and application method thereof

The invention discloses a closed enema system and an application method thereof, and belongs to the field of medical instruments, and the closed enema system comprises a perfusion pipeline used for being connected with a perfusion device for conveying enema liquid; the liquid discharging pipeline is used for being connected with a liquid discharging device for sucking intestinal contents; the outer wall of the drainage pipeline is sleeved with a turbidity sensor which is used for monitoring the turbidity of drainage liquid in real time; the filling pipeline and the liquid discharging pipeline are respectively communicated with the confluence pipeline; the controller is electrically connected with the turbidity sensor, the filling device and the liquid discharging device respectively; the controller is configured to receive monitoring data of the turbidity sensor in a liquid discharge stage and determine whether to start a next lavage cycle or not according to a comparison result of the data and a preset threshold value; and meanwhile, the filling device and the liquid discharging device are controlled to operate in a time-sharing manner. By means of the arrangement, preoperative clysis operation can be efficiently and rapidly completed in a patient-friendly mode.
Owner:PEKING UNIVERSITY FIRST HOSPITAL (PEKING UNIVERSITY FIRST CLINICAL MEDICAL COLLEGE)

A composition with satiety and weight control and anti-aging functions, and a preparation method and application thereof

The present application provides a composition with satiety and weight control and anti-aging, and a preparation method and application thereof. The composition comprises the following raw materials by weight: polysaccharide 11-13 parts, fiber powder 20-25 parts, highland barley powder 12-18 parts, compound powder 18-23 parts, pectin 4-8 parts, ganoderma lucidum powder 6-9 parts, and compound protein 8-12 parts, and relates to the technical field of satiety and weight control and anti-aging compositions. The composition can form an effect of hindering nutrient absorption or prolonging gastric emptying, increase the volume of intestinal contents to achieve satiety, thereby achieving the functions of well controlling weight gain and reducing body weight. In addition, the composition can activate the body's antioxidant enzyme system, improve the activity of superoxide dismutase (SOD), and reduce the content of malondialdehyde (MDA), thereby delaying cell aging and achieving the anti-aging effect.
Owner:XINYI (TIANJIN) BIOTECHNOLOGY CO LTD

Intestinal micro-needle anastomosis stent with antibacterial function and preparation method and application thereof

ActiveCN121401509BThe anastomosis went smoothlyreduce tensionSurgeryCoatingsBerberine hydrochlorideAnti bacterial
The application discloses an intestinal micro-needle anastomosis stent with an antibacterial function and a preparation method and application thereof, which can effectively physically isolate an anastomotic stoma from intestinal contents, provides a relatively clean local environment for healing of the anastomotic stoma, and further reduces tension at the anastomotic stoma by fixing the micro-needle anastomosis stent at the anastomotic stoma, so that anastomotic leakage caused by excessive tension is avoided; a micro-needle layer on a surface of the stent can realize in-situ long-acting slow release of berberine hydrochloride (BBH) on a superficial layer of the anastomotic stoma, so that drug utilization of the BBH is improved, and occurrence of initial inflammation of the anastomotic stoma is effectively reduced, and healing of the anastomotic stoma is better regulated. Animal experiment results prove that implantation of the micro-needle anastomosis stent can effectively reduce inflammatory cell infiltration of local tissues, reduce anastomotic arrangement, and regulate smooth healing of the anastomotic stoma.
Owner:WENZHOU INST UNIV OF CHINESE ACAD OF SCI

A method for promoting intestinal flora against cell fibrosis based on polysaccharides and an experimental method thereof

The application discloses a method for improving the anti-cellular fibrosis of intestinal flora based on polysaccharides, and the steps of the method include: preparing Yunnan rhizoma polygonati mutant polysaccharide PKVP-1; and placing the Yunnan rhizoma polygonati mutant polysaccharide PKVP-1 in an intestinal environment to improve the anti-cellular fibrosis of intestinal flora. The steps of an experimental method for improving the anti-cellular fibrosis of intestinal flora based on polysaccharides include: selecting experimental animals and performing random grouping, and then performing drug administration; collecting the intestinal contents and kidney tissues of the experimental animals; taking the kidney tissues of the experimental animals to prepare paraffin sections for trichrome staining, and evaluating the inflammation degree of the kidney tissues according to the inflammatory cell infiltration; performing sequencing; detecting metabolites and obtaining a conclusion according to metabolite analysis. The method for improving the anti-cellular fibrosis of intestinal flora based on polysaccharides provided by the application improves the anti-cellular fibrosis ability of intestinal flora by placing the mutant polysaccharide in the intestinal environment of the experimental animals.
Owner:HUNAN SHISHANGKANG AGRI CO LTD

Reagent for detecting porcine rotavirus and nanozyme immunochromatography test strip and application thereof

The present application relates to a kind of reagent and nanozyme immunochromatography test strip for detecting porcine rotavirus and its application, belong to biotechnology field, the present application is aimed at solving the technical problem of low sensitivity and poor specificity of existing porcine rotavirus detection method, its technical scheme main points are in containing capture antibody and detection antibody, the capture antibody is monoclonal antibody one, and the detection antibody is monoclonal antibody two, vice versa;Wherein the heavy chain variable region of monoclonal antibody one includes the sequence shown in SEQ ID NO:1, and the light chain variable region includes the sequence shown in SEQ ID NO:2;The heavy chain variable region of monoclonal antibody two includes the sequence shown in SEQ ID NO:5, and the light chain variable region includes the sequence shown in SEQ ID NO:6.The reagent can be used for preparing nanozyme immunochromatography test strip, realize the high sensitivity, high specificity detection of porcine rotavirus, suitable for the rapid detection of pig anal swab, feces or intestinal contents sample.
Owner:INST OF URBAN AGRI CHINESE ACADEMY OF AGRI SCI +1

Balloon catheter with flushing structure

ActiveCN223818019UBalloon catheterEnemata/irrigatorsBalloon catheterCatheter irrigations
The utility model discloses a balloon catheter with a flushing structure. The balloon catheter solves the problem that an anastomotic stoma cannot be flushed in the prior art. The device comprises a blocker fixed at the front end of an anastomotic stoma, a catheter which is arranged in the blocker and is used for discharging intestinal contents, a balloon which is arranged on the outer wall of the catheter and is sealed with the inner wall of the blocker after being expanded, and a medium conveying mechanism which is connected with the catheter, is communicated with the balloon through the catheter and is used for conveying a medium, and the flushing mechanism is connected with the catheter and flushes the intestinal anastomotic stoma through the catheter. When suppuration occurs in the anastomotic stoma or intestinal secretions exist in the anastomotic stoma, the flushing mechanism sprays the flushing medium to the anastomotic stoma through the catheter, so that the anastomotic stoma is flushed, and intestinal suppuration or intestinal secretions are prevented from being attached to the anastomotic stoma to affect healing of the anastomotic stoma.
Owner:SICHUAN QIMING RUIKANG TECHNOLOGY CO LTD

An ostomy irrigation device

The application provides a stoma irrigation device, belonging to the field of stoma irrigation, and used for solving the problem of limited physical stimulation to the intestinal tract during stoma irrigation operation; the device comprises an insertion unit, a first liquid injection unit and a second liquid injection unit; the insertion unit comprises a first expansion piece, a second expansion piece and a flow rate adjusting piece arranged in sequence along an insertion direction; the first expansion piece is arranged, and the first liquid injection unit is used to inject gas or liquid into the first expansion piece, so that the first expansion piece is expanded, thereby fixing the insertion unit in the intestinal tract and avoiding leakage of the irrigation liquid; the second liquid injection unit is used to inject the irrigation liquid into the second expansion piece, so that the second expansion piece is expanded to actively induce intestinal peristalsis, change the traditional passive flushing mode, make the intestinal contents more easily softened and removed by peristalsis, shorten the cleaning time and improve the cleanliness; and the irrigation liquid enters the intestinal tract at a slow speed after being adjusted by the flow rate adjusting piece, so that the intestinal mucosa is protected and the discomfort of the patient is reduced.
Owner:CHONGQING UNIV CANCER HOSPITAL

Turnover catheter device for ileum fistulization

ActiveCN223817932UBalloon catheterSuction devicesIntestine obstructionCatheter device
The utility model relates to the technical field of medical instruments, in particular to an ileum fistulization bypass catheter device. The ileum fistulization bypass catheter device comprises a first catheter body, the front end of the first catheter body is of an open structure, a plurality of first through holes are formed in the side portion of the first catheter body, and an air bag assembly is arranged on the rear section of each first through hole; a connecting port is formed in the tube tail of the first tube body, and a drainage bag is detachably connected to the outer side of the connecting port; a first branch tube communicated with the air bag assembly is arranged on one side of the tube tail of the first tube body, and an air injection valve used for injecting air into the air bag assembly or exhausting air from the air bag assembly is installed on the first branch tube, so that the function of cutting off an enteric cavity (namely air bag intestinal obstruction) is achieved, intestinal contents can be transferred through a catheter, and the risk of leakage of an anastomotic stoma is reduced. The nursing bed is easy to operate, convenient to nurse and easy to accept by patients and family members, and pain caused by treatment of the patients is greatly reduced.
Owner:晋江市医院(上海市第六人民医院福建医院)

A system for predicting the time of occurrence of a peak in blood non-esterified fatty acid concentration in a dairy cow postpartum

The application discloses a system for predicting the occurrence time of the peak value of the non-esterified fatty acid concentration in the blood of a dairy cow after delivery, and belongs to the technical field of healthy breeding of dairy cows. The system takes the genus level relative abundance of five marker microorganisms in the intestinal contents of a dairy cow one week before delivery as input data, calculates a score through a preset discriminant model, and judges whether the peak value of the blood free fatty acid concentration after delivery occurs on the day of calving according to a set threshold. The overall prediction accuracy of the discriminant model reaches 90%, the prediction accuracy for dairy cows with a peak on the day of calving reaches 75%, the system is simple to operate and stable in performance, can realize pre-delivery early warning of high health risks of peripartum dairy cows, provides technical support for taking preventive measures in advance, improving the postpartum health status and lactation level of dairy cows, and has important practical application value and economic significance.
Owner:ZHEJIANG UNIV

Recirculating distal intestinal content

A recirculation system for recirculating intestinal content within an intestinal tract of a subject including a recirculation pathway extending from a distal portion of the intestinal tract to a proximal portion of the intestinal tract forming a recirculation loop for recirculating the intestinal content through the proximal portion of the intestinal tract to increase nutrient absorption from the intestinal content. A bypass pathway in fluid communication with the recirculation pathway and configured to divert the intestinal content from the recirculation pathway to continue along the intestinal tract.
Owner:SAINT LOUIS UNIV

Lactobacillus plantarum and application thereof in fatty liver of laying hens

The present application relates to a kind of lactobacillus plantarum and its application in egg hen fatty liver, the lactobacillus plantarum (Lactobacillus plantarum) CK3 is isolated, screening is obtained from the intestinal contents of Hainan Wenchang chicken and its fecal sample, and is preserved in China typical culture preservation center on December 23, 2024, and the preservation number is CCTCC NO: M20242886, it has good tolerance in the environment of 40~55 DEG C, pH=2~4, 0.3% bile salt, 1.4% trypsin, and can reduce the liver lipid accumulation of egg hen caused by high-energy feed, liver inflammation, liver damage, reduce liver antioxidant stress, significantly improve egg hen fatty liver, while can improve the intestinal injury, intestinal inflammation and oxidative stress of fatty liver egg hen caused by high-energy feed, with important application significance and value.
Owner:SANYA INSTITUTE OF NANJING AGRICULTURAL UNIVERSITY

Bacillus tequilensis G4 and application thereof

The invention discloses bacillus tequilensis G4 and application thereof, the bacillus tequilensis G4 is a strain G4 which is screened from intestinal contents of penaeus vannamei and has a bacteriostatic effect on four pathogenic bacteria, and the strain G4 is identified as the bacillus tequilensis through 16S rDNA (ribosomal deoxyribonucleic acid) sequences. And then separating and purifying the antibacterial substance, and exploring the inhibition mechanism of the coarsely extracted antibacterial substance on four pathogenic bacteria. According to the invention, the bacillus tequilensis G4 crude extract bacteriostat is also applied to pork preservation.
Owner:JIANGSU OCEAN UNIV

Anti-fouling sticker for enteroscopy

1. The name of the design product: intestinal mirror anti-pollution paste. 2. The use of the design product: cooperate with intestinal mirror, paste in the perianal part to prevent intestinal contents from overflowing. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective drawing.
Owner:NINGBO MEDICAL CENT LIHUILI HOSPITACL

External drainage device for intestinal obstruction and use method therefor

PCT designated stageWO2026175103A1Intestinal ObstructionsIntestino-intestinal
Disclosed are an external drainage device for intestinal obstruction and a use method therefor, belonging to the technical field of medical devices, and solving the problems in the prior art that an air bag may slide out of a support tube during use, and the support tube cannot be synchronously disintegrated. The present invention comprises a support tube fixed in the intestinal tract at the front end of an anastomotic stoma, a blocking mechanism arranged in the support tube and used for blocking the circulation of intestinal contents and preventing the intestinal contents from flowing through the inner wall of the support tube, a limiting mechanism arranged on the inner wall of the support tube and used for preventing the blocking mechanism from sliding, and disintegration mechanisms respectively arranged at two ends of the support tube and used for synchronous disintegration of the support tube and the limiting mechanism. In the present invention, the limiting mechanism is arranged on the inner wall of the support tube, and the limiting mechanism abuts against one end of the blocking mechanism, so as to prevent the contents from passing through the anastomotic stoma when the blocking mechanism slips off during use, and the support tube is left in the intestinal tract to self-disintegrate. The support tube is provided with the disintegration mechanisms, and the disintegration mechanisms can facilitate synchronous disintegration of other parts of the external drainage device for intestinal obstruction.
Owner:四川启明瑞康科技有限公司

Preparation method and application of glutamic acid-enriched flora in pig intestinal tracts

The invention relates to the field of animal nutrition and intestinal microecology regulation and control, and discloses a preparation method and application of a pig intestinal glutamic acid-enriched flora. Comprising the following steps: acquiring small intestine contents of healthy piglets in a lactation period, preparing into an intestinal bacterium inoculum under an anaerobic condition, inoculating the intestinal bacterium inoculum into a culture medium added with glutamic acid, and performing continuous subculture so as to enrich directionally-enriched intestinal bacteria capable of metabolizing glutamic acid and generating mixed active amino acid metabolites and metabolites of the directionally-enriched intestinal bacteria. According to the method, the dominant flora with the glutamic acid metabolism function in the small intestines of the pigs is screened, and a mother-piglet integrated transplantation system is established, so that early intervention on development of the intestinal tracts of the piglets and establishment of healthy intestinal bacteria can be realized, the intestinal flora structure and the metabolism function of the piglets can be adjusted, the development of the intestinal tracts can be promoted, and the growth performance of the piglets can be improved.
Owner:CHINA AGRI UNIV

A long-spined sea star distribution monitoring method based on fish intestinal contents detection

The application discloses a long-spined sea star distribution monitoring method based on fish intestinal content detection. The method obtains information of fish preying on long-spined sea stars and seasonal feeding habits in a target water area, and optimally selects detection fish species suitable for different seasons; combines fish food digestion capacity data to establish a layered position change model of intestinal contents over time; extracts intestinal contents of the detection fish species in layers and detects the concentration of long-spined sea star DNA fragments in the intestinal contents to determine the feeding time; combines fish activity characteristic data, reversely deduces the space-time distribution characteristics of long-spined sea stars in the target water area based on a Bayesian probability distribution model, and generates a distribution probability graph. The method has the advantages of strong non-direct interference, wide adaptability, high timeliness and the like, and can provide a scientific basis for long-spined sea star prevention and control management and ecological risk assessment.
Owner:SOUTH CHINA SEA FISHERIES RES INST CHINESE ACAD OF FISHERY SCI

Intelligent enema system and method for promoting intestinal rehabilitation of people with special needs

The invention relates to the technical field of medical equipment, in particular to an intelligent enema system and method for promoting intestinal rehabilitation of people with special needs, and the system comprises an enema execution assembly, an electromagnetic flow detection module, an anti-reflux assembly and an eddy current generation module. An electromagnetic flow detection module monitors the flow of enema liquid, an anti-backflow assembly prevents the enema liquid and intestinal contents from flowing back through a one-way sealing valve seat and an elastic plugging piece, a flow-pressure matching algorithm is built in a control unit, and the conveying rate of the enema liquid can be dynamically adjusted according to intestinal environment parameters; the vortex generating module can convert enema liquid into a vortex form, so that vortex type perfusion is realized; the control unit has identity recognition and memory functions and can read information of the bracelet of the patient and record use data. The traditional Chinese medicine composition is suitable for people with special needs of long-term constipation, enterostomy, anus and rectum operations and the like, can efficiently relieve constipation and promote intestinal function recovery, has safety and convenience, and is suitable for medical institutions and family scenes.
Owner:HAINAN VOCATIONAL COLLEGE OF SCI & TECH

Transanorectal decompression threaded tube for preventing anastomotic fistula after rectal cancer operation

The invention relates to the technical field of medical instruments, in particular to a transanorectal decompression threaded tube for preventing anastomotic fistula after a rectal cancer operation. The intestinal decompression threaded tube is provided with the side holes, the openings of the side holes are upwards distributed along the circumference of the concave part of the threads, the threaded structure can avoid narrowing and blocking of a drainage tube cavity while adapting to intestinal bending, and the design of the side holes is beneficial to drainage of intestinal contents and prevention of intestinal mucosa injury. The negative pressure drainage device is soft in texture and can adapt to contraction and closing states of muscles near the anorectal ring, the dynamic active drainage intestinal decompression effect is exact through negative pressure suction, intestinal contents can be diluted through the flushing pipe, and the probability that the intestinal contents block the suction inner pipe is reduced. The threaded outer tube and the attractable inner tube can be detached at any time, so that residual intestinal contents between the threaded tube cavity and the attractable inner tube can be cleaned conveniently. Through the intestinal decompression effect of the transanorectal decompression threaded tube, a patient can eat at an early stage, and the occurrence risk of anastomotic fistula can be obviously reduced.
Owner:TIANJIN BAODI HOSPITAL

Bacillus velezensis nxpm130 for inhibiting erysipelothrix rhusiopathiae and application thereof

PendingCN122326488AFecesErysipelothrix
This invention discloses a strain of *Bacillus belyssima* NXPM130 that inhibits *Erysipelothrix rhusiopathiae* and its applications, belonging to the field of microbial technology. The *Bacillus belyssima* NXPM130 has the accession number CGMCC No. 24334. This strain was obtained through targeted screening and identification of *Erysipelothrix rhusiopathiae* as a specific target from the intestinal contents of healthy piglets. In vitro antibacterial tests and in vivo models in piglets validated that this strain not only significantly reduces the *Erysipelothrix rhusiopathiae* load in the intestines and feces but also improves intestinal barrier function and promotes growth performance. This invention fills the technological gap in specific probiotic spores targeting *Erysipelothrix rhusiopathiae*, providing a safe, efficient, and drug-resistant new biocontrol solution for pig farming.
Owner:HUNAN NORMAL UNIVERSITY

Device and method for separating and recovering intestinal contents and extract thereof

A device and method for separating and recovering intestinal contents, comprising removing the impurities from the intestinal contents by means of coarse filtration and cross-flow fine filtration, followed by obtaining a concentrate by microporous membrane cross-flow filter, and collecting the target contents. The microporous membrane has a spongy porous structure, and can rapidly and effectively achieve the separation and recovery of flora from the intestinal contents by cooperation with cross-flow filtration. The separated and recovered dry flora comprises at least 10-20% of the initial wet intestinal contents, and comprises at least 1011 / 1 g dry flora.
Owner:QIHUI BIOTECHNOLOGY YANGZHOU CO LTD

Construction method and application of Eriocheir sinensis intestinal flora deletion model

The invention discloses a construction method and application of an Eriocheir sinensis intestinal flora deletion model, the method comprises the following steps: feeding Eriocheir sinensis with a feed mixed with mixed antibiotics for 96 hours to obtain the Eriocheir sinensis intestinal flora deletion model; the mixed antibiotic is prepared from metronidazole, neomycin and vancomycin. A plate culture method verifies that the optimized core antibiotic concentration group can enable the clearance rate of intestinal content florae to reach 95% or above and the clearance rate of fecal florae to reach 90% or above. According to the method, the intestinal flora deletion model of the eriocheir sinensis is constructed for the first time, the method has the advantages of being high in removal efficiency, good in repeatability, small in stress and the like, the flora is restorable after drug administration is stopped, and a standardized experimental tool is provided for studying the intestinal-brain axis mechanism, physiological metabolism and healthy breeding of crustacean.
Owner:NANJING NORMAL UNIVERSITY

Bacillus velezensis with the ability of degrading vomitoxin and multiple enzyme activities and application thereof

PendingCN122445518AAmylasePectinase
The present application belongs to the technical field of mycotoxin biodegradation and bacillus velezensis, and particularly relates to a bacillus velezensis strain with degrading vomitoxin and multiple enzyme activities and application thereof. The strain is isolated from pig intestinal contents, and is identified by morphological identification, physiological and biochemical identification, and 16S rRNA and gyrB gene molecular identification, and is confirmed as bacillus velezensis, and is named as bacillus velezensis YK-19 (Bacillus velezensis YK-19). The strain has a degrading rate of vomitoxin (deoxynivalenol, DON) as high as 93.79%, and has multiple enzyme activities such as protease, amylase, beta-mannanase, xylanase, cellulase and pectinase, and does not have hemolytic activity, and has good biological safety. The strain also shows good acid resistance, bile salt resistance, salt resistance and high temperature resistance, and has a wide application prospect in actual production.
Owner:HENAN INST OF SCI & TECH

An enterostomy plug

The application discloses an intestinal fistula plug, which comprises a sponge plug and a suction tube; the suction tube is connected with a negative pressure suction device; the suction tube comprises a first suction tube and a second suction tube; the diameter of the first suction tube is larger than that of the second suction tube; the first suction tube penetrates through the sponge plug, the end of the first suction tube is in a spherical structure, and the spherical structure is provided with a side hole; the second suction tube spirals in the sponge plug, and the second suction tube is provided with a side hole; and the surface of the sponge plug is provided with a protective plastic film. The intestinal fistula plug can effectively control the outflow of intestinal contents and can make the wound around the stoma heal faster, thereby reducing the pain of patients and the working intensity of medical staff.
Owner:PEKING UNION MEDICAL COLLEGE HOSPITAL