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19839 results about "Anti bacterial" patented technology

Organ transport container with antiviral therapy

ActiveUS12245585B2BiotechnologyMicroorganism
A system for the hypothermic transport of biological samples, such as tissues, organs, or body fluids. The system includes an antimicrobial treatment mechanism to inactivate microbes flushed from the biological sample by preservation fluid flowed therethrough. The self-purging preservation apparatus is placed in an insulated transport container having a cooling medium. When assembled, the system allows for transport of biological samples for extended periods of time at a stable temperature while simultaneously treating microbial infections to prevent transmission between a donor and a recipient.
Owner:PARAGONIX TECHNOLOGIES INC

Timber antiseptic agent

To provide a timber antiseptic agent which exhibits superior safety and superior antibacterial performance with low influence on the human body and environment.SOLUTION: The present invention relates to a timber antiseptic agent containing an alkyl 4-hydroxybenzoate represented by formula (1) [where R represents an alkyl group having 5 to 10 carbon atoms] or a salt thereof.SELECTED DRAWING: None
Owner:UENO PHARMA CO LTD

Small-molecule antibacterial polypeptide, and preparation method therefor and use thereof

Provided are a small-molecule antibacterial polypeptide, and a preparation method therefor and a use thereof. The antibacterial peptide provided has stronger antibacterial activity than most other derivative polypeptides and antibacterial polypeptides disclosed in existing reports. Multiple strains known for drug resistance are used to carry out bactericidal activity evaluation. The result shows that the antibacterial peptide provided has broad-spectrum antibacterial activity against drug-resistant strains, achieves more comprehensive antibacterial effects, and has a wider range of indications.
Owner:SHENZHEN ICARBONX INTELLIGENT PEPTIDE PHARM TECH CO LTD

Preparation method and application of multifunctional self-healing hydrogel material capable of resisting bacteria and inflammation and promoting healing of diabetic wounds

ActiveCN119371683Apromote healinggood cell compatibilityBandagesWound.exudateBiochemistry
The invention discloses a preparation method and application of a multifunctional self-healing hydrogel material with antibacterial, anti-inflammatory and diabetic wound healing promotion functions. The preparation method comprises the following steps: firstly, synthesizing silver-doped carbon quantum dots (AgCD) in one step through a hydrothermal method; the preparation method comprises the following steps: firstly, preparing sodium hyaluronate (HA), secondly, oxidizing the sodium hyaluronate (HA) into oxidized hyaluronic acid (OHA) by taking sodium periodate as an oxidizing agent, and then encapsulating AgCD and metformin (Met) into hydrogel formed by Schiff base reaction between carboxymethyl chitosan (CMCS) and the oxidized hyaluronic acid (OHA). The hydrogel provided by the invention has certain adhesion, suitable capacity of absorbing wound exudate and good biocompatibility, meanwhile, due to the addition of AgCD, the hydrogel has excellent antibacterial property, and the metformin can promote angiogenesis of a wound part, so that the hydrogel can better promote healing of a diabetic wound. The hydrogel is simple and rapid in preparation method, has low biotoxicity and antibacterial property, and provides a strategic choice for promoting healing of diabetic wounds.
Owner:HEFEI UNIV OF TECH

Antimicrobial device comprising a cap with ring and insert

Systems, methods, and devices for providing an antimicrobial composition to the proximal elements of a transdermal catheter and into the lumen of the transdermal catheter are disclosed. In an embodiment, the device includes a cap configured to be removably secured to the hub, the cap comprising a ring member comprising first threads for engaging second threads on the hub of the transdermal catheter, the ring member having an opening through its interior; and an insert member secured within the opening of the ring member; wherein the insert member comprises an antimicrobial composition and the ring and insert member do not readily rotate with regard to one another.
Owner:ICU MEDICAL INC

Antibacterial peptide and antibacterial application thereof

The invention discloses an antibacterial peptide and antibacterial application thereof. The amino acid sequence of the antibacterial peptide is as shown in SEQ ID No.1, and the C end of the antibacterial peptide is amidated. The antibacterial peptide provided by the invention has the activity of resisting staphylococcus aureus and escherichia coli, and plays a role in inhibiting bacteria by destroying cell membranes. The antibacterial peptide is excellent in antibacterial activity, good in stability and not prone to generating drug resistance, can be used for synthesizing and preparing antibacterial compositions, and has great potential in application in the fields of food and medicine.
Owner:JINHUA INSTITUTE OF ZHEJIANG UNIVERSITY

Broad-spectrum antibacterial peptide SS-7 and application thereof

The invention discloses a broad-spectrum antibacterial peptide SS-7 and application thereof, and belongs to the field of biological medicine. The amino acid sequence of the broad-spectrum antibacterial peptide SS-7 disclosed by the invention is VRRVRFVVLRRIKKWRRI, and the broad-spectrum antibacterial peptide SS-7 has a remarkable inhibition effect on various gram-positive bacteria and gram-negative bacteria such as drug-resistant strains such as methicillin-resistant staphylococcus aureus (ATCC43300) and shows low toxicity and no hemolytic toxicity on eukaryotic cells and red blood cells of mammals; lPS and lipoteichoic acid on the surfaces of bacteria can be combined to achieve the effect of neutralizing the bacteria, and a very good treatment and protection effect is achieved on animals infected by the bacteria. The antibacterial peptide SS-7 can be used for preparing an antibacterial agent and preparing a medicine for preventing or treating bacterial infection, has the advantages of being wide in antibacterial spectrum, low in drug-resistant mutation frequency, low in toxicity and low in production cost, can effectively solve the current bacterial drug resistance problem, and has wide application prospects and important clinical value.
Owner:HUAZHONG AGRI UNIV

Medical device with antimicrobial properties

Devices and methods for delivering an antimicrobial composition to a medical device to prevent infection and microbial ingress in medical devices. An embodiment of the device includes a male connector with a distal tip and a recess at the distal tip configured to deliver an antimicrobial composition into solution within a cavity formed by the recess. The surface of the recess includes an antimicrobial composition. In certain implementations, the antimicrobial composition contains chlorhexidine acetate.
Owner:ICU MEDICAL INC

Preparation method of antibacterial anti-mite healthy cotton fiber based on compounding of copper-silver alloy and graphene fiber

The invention relates to a preparation method of antibacterial and anti-mite healthy cotton fibers based on compounding of copper-silver alloy and graphene fibers. The preparation method comprises the following steps: synthesizing Cu-Ag alloy with a pomegranate-shaped structure, preparing copper-silver core-shell double-metal nanoparticles, preparing a copper-silver double-metal core-shell nanoparticle material, performing surface modification on a copper antibacterial agent, preparing a nano anti-mite antibacterial finishing agent, preparing a graphene / carbon nanofiber composite material, and preparing the antibacterial anti-mite healthy cotton fiber. A vacuum hot pressing method and a sintering method are creatively combined, and the prepared antibacterial anti-mite healthy cotton fiber endows bedding with excellent antibacterial, anti-mite and various healthy functions and has the advantages of excellent antibacterial performance, efficient anti-mite function, improved tensile strength and the like.
Owner:HEYE HEALTH TECH CO LTD

Antibacterial plastic and preparation method thereof

ActiveCN119591980AHigh antibacterial efficiencygood compatibilityPolypropyleneAnti bacterial
The invention provides antibacterial polypropylene plastic, and aims to obtain a composite antibacterial agent with the advantages of an inorganic antibacterial agent and an organic antibacterial agent by compounding the inorganic antibacterial agent and the organic antibacterial agent, and the antibacterial polypropylene plastic which is good in antibacterial property, good in migration resistance, good in mechanical property, good in mechanical property, good in mechanical property and the like is obtained by adding the obtained composite antibacterial agent into the polypropylene plastic. The invention discloses antibacterial polypropylene plastic with long-acting antibacterial property.
Owner:江西米娅新材料有限公司

Broad-spectrum antibacterial peptide, antibacterial agent and application

The invention provides a broad-spectrum antibacterial peptide, an antibacterial agent and application, and belongs to the technical field of biological medicine. The invention provides a broad-spectrum antibacterial peptide. The broad-spectrum antibacterial peptide comprises an amino acid sequence as shown in SEQ ID No. 1. The minimum inhibitory concentration of the antibacterial peptide to gram-positive bacteria, gram-negative bacteria and fungi proves that the antibacterial peptide has obvious antibacterial activity to the gram-positive bacteria, the gram-negative bacteria and the fungi. The invention also verifies the minimum inhibitory concentration of the antibacterial peptide to clinical drug-resistant bacteria. The cytotoxicity of the SL-12 disclosed by the invention is relatively weak, the SL-12 only shows obvious cytotoxicity at 200 [mu] g / ml, and the minimum inhibitory concentration of the SL-12 is 6.25-12.5 [mu] g / ml; the SL-12 has no obvious hemolytic activity when the concentration is 100 [mu] g / ml or lower, and is high in safety.
Owner:KUNMING INST OF ZOOLOGY CHINESE ACAD OF SCI

Antibacterial ceramic and preparation method thereof

The invention provides antibacterial ceramic and a preparation method thereof. The antibacterial ceramic comprises a blank body and a glaze layer, the blank body is prepared from the following raw materials: kaolin, diatomite, montmorillonite, soapstone, bamboo charcoal powder, a first antibacterial agent, a fluxing agent, a pore forming agent, an adhesive and a reinforcing agent; the glaze layer comprises the following raw materials: kaolin, diatomite, dolomite, tourmaline, sodium oxide, a second antibacterial agent, a binder, a stabilizer and a dispersant. The method comprises the following steps: firing a molded green body by adopting stepped segmented heating, and carrying out glaze firing by adopting stepped segmented heating after glazing, thereby obtaining the antibacterial ceramic. According to the antibacterial ceramic disclosed by the invention, the antibacterial agent is added into the green body and the glaze layer, so that the influence on the antibacterial property of the green body in the firing process of the green body is avoided, the antibacterial durability is further improved, the antibacterial effect is enhanced, and the antibacterial rate on pathogenic bacteria such as escherichia coli and staphylococcus aureus reaches 99.99%.
Owner:DEHUAQIAO CRAFTSMAN CERAMIC TECH CO LTD

SnO2 / SnS2 / Ag2S nano material for whitening and sterilizing teeth through piezoelectric electro-catalysis

PendingCN119632857AEasy to operateNo harm to the surface structure of the teethCosmetic preparationsMaterial nanotechnologyHeterojunctionTooth whitening
The invention discloses a SnO2 / SnS2 / AgS nano material with piezoelectric electro-catalytic tooth whitening and sterilizing performance and a preparation method and application thereof, and the preparation method comprises the following steps: (1) dripping a silver nitrate aqueous solution into a prepared SnO2 / SnS2 nano material aqueous dispersion, carrying out hydro-thermal treatment for 2 hours, centrifuging, washing and drying to obtain a SnO2 / SnS2 / Ag2S ternary semiconductor heterojunction nano material; (2) food indigo is adopted to simulate tooth surface pigments, piezoelectric electro-catalytic degradation is carried out by using the SnO2 / SnS2 / Ag2S ternary semiconductor heterojunction nanomaterial, and the pigment degradation efficiency can reach 95% or above; (3) the SnO2 / SnS2 / Ag2S heterojunction nanomaterial is used for piezoelectric electro-catalysis treatment of the streptococcus mutans pellicle, and the antibacterial rate of the pellicle can reach 90% or above; and (4) compared with a 3% H2O2 aqueous solution for treating the enamel surface structure, the SnO2 / SnS2 / Ag2S nano-material piezoelectric electro-catalysis treatment of teeth has small damage to the enamel surface structure. According to the invention, more nano materials with tooth whitening and sterilizing performance and the preparation method thereof are provided, so that the problems of single variety, single preparation method, low electron-hole separation efficiency and large side effect of the existing tooth whitening and sterilizing nano materials are solved.
Owner:HARBIN INST OF TECH

Antibacterial peptide generation method and device based on generative model and computer equipment

The invention relates to an antibacterial peptide generation method and device based on a generative model and computer equipment, and relates to the technical field of artificial intelligence and bioinformatics. Predicting the novel antibacterial peptide on the basis of the existing antibacterial peptide sequence by using a pre-trained generative model to obtain a predicted sequence; inputting the prediction sequence into a pre-trained antibacterial peptide classifier, and judging whether the prediction sequence has antibacterial activity or not; the antibacterial peptide classifier is obtained by training based on an antibacterial peptide tag set and a non-antibacterial peptide sequence tag set; and outputting the prediction sequence with the antibacterial activity as a final target antibacterial peptide sequence, so that the problem of low antibacterial peptide design generation efficiency is solved, de novo generation and judgment of the antibacterial peptide can be realized by virtue of a generative model and a classifier, and the generation efficiency and accuracy are improved.
Owner:ZHEJIANG LAB +1

Waterproof and moisture-permeable composite fabric based on bio-based material and preparation method of waterproof and moisture-permeable composite fabric

The invention relates to the technical field of multi-layer composite fabrics, and discloses a waterproof moisture-permeable composite fabric based on a bio-based material and a preparation method of the waterproof moisture-permeable composite fabric. The preparation method comprises the following steps: preparing an amino silanized zinc oxide / cellulose nanocrystal composite material, and carrying out mixed condensation polymerization on the amino silanized zinc oxide / cellulose nanocrystal composite material and vanillin cyclic carbonate to obtain an antibacterial agent; castor oil-based polyurethane, an antibacterial agent and a solvent are mixed and then subjected to electrostatic spinning, and after the electrostatic spinning and the pretreated polyester fabric are subjected to hot-pressing compounding, the obtained composite fabric has excellent waterproof and moisture permeable performance and good antibacterial performance.
Owner:WUJIANG TUTAIKE TEXTILE & FINISHING CO LTD

Ruthenium-doped Prussian blue nano-enzyme, preparation method and application thereof, SNP-PB nano-enzyme and application thereof

The invention relates to the technical field of nano material application. The invention provides a ruthenium-doped Prussian blue nano-enzyme and a preparation method thereof. The ruthenium-doped Prussian blue nano-enzyme is obtained by reacting metal ruthenium with Prussian blue nano-particles at normal temperature. The invention further provides a nano-enzyme library containing the ruthenium-doped Prussian blue nano-enzyme and a construction method of the nano-enzyme library. The invention also provides the SNP-PB nano-enzyme obtained by loading sodium nitroprusside on the ruthenium-doped Prussian blue nano-enzyme. The ruthenium-doped Prussian blue nano-enzyme and the SNP-PB nano-enzyme both have good antibacterial and anti-inflammatory performance, after NO gas release capacity is given, the problem of resistance of a biological membrane is better solved, then oxidative stress resistance and periodontal bacterial infection resistance are better exerted, and a new treatment method is provided for periodontal diseases.
Owner:PEKING UNIV SCHOOL OF STOMATOLOGY

Pharmaceutical composition for preventing and treating gingival atrophy and preparation method and application thereof

InactiveCN119405788Areduce atrophyto promote metabolismConnective tissue peptidesOrganic active ingredientsBiotechnologyCalendula officinalis extract
The invention provides a pharmaceutical composition for preventing and treating gingival atrophy and a preparation method and application thereof, and belongs to the technical field of biological medicine. The composition contains finless eel peptide, skipjack elastin peptide, quinoa rice extract, gleditsia sinensis rice extract, calendula extract, chamomile extract, chitosan, peach gum, hydroxyapatite and the like, and the finless eel peptide, the skipjack elastin peptide, the quinoa rice extract and the gleditsia sinensis rice extract are specific enzymatic hydrolysates. The monopterus albus peptide, the skipjack elastin peptide, the quinoa rice extract and the gleditsia sinensis rice extract jointly promote repair and regeneration of gingival tissues. The calendula extract, the chamomile extract and the chitosan have anti-inflammatory and antibacterial effects, so that gingival inflammation is relieved, and bacterial infection is prevented. And the chitosan and the calendula extract can accelerate the repair of damaged gingival tissues. The monopterus albus peptide, the skipjack elastin peptide and the hydroxyapatite are matched for use to jointly maintain the normal structure and function of gingiva. All the components have a synergistic effect, so that gingival atrophy can be effectively prevented and improved.
Owner:HUBEI SHUANGXING PHARMA CO LTD

Curtain fabric with antibacterial function and preparation method thereof

The invention relates to the field of spinning, and particularly discloses a curtain fabric with an antibacterial function and a preparation method thereof.The curtain fabric comprises a base fabric layer, an antibacterial layer and a surface layer, and the antibacterial layer is formed after the surface of the base fabric layer is coated with an antibacterial agent; the antibacterial agent at least comprises composite modified titanium dioxide particles loaded with nano-silver and an OPHB bio-based antibacterial stock solution; wherein the modified titanium dioxide particles are prepared by loading nano-silver on titanium dioxide and then modifying the titanium dioxide through polyethyleneimine and a silane coupling agent; the preparation method comprises the following steps: coating the surface of the base cloth layer with an antibacterial agent, and then drying to form the antibacterial layer; the side, provided with the antibacterial layer, of the base cloth layer is attached to the surface layer and subjected to hot press molding, and the curtain cloth with the antibacterial function is prepared and has the advantages that the curtain cloth with the good antibacterial effect is prepared, meanwhile, the cost is reduced, and the antibacterial durability is improved.
Owner:SHAOXING XIAOXUANCHUANG FABRIC CO LTD

Transparent polypropylene medical plastic cup and preparation method thereof

The invention relates to the technical field of plastic cups, in particular to a transparent polypropylene medical plastic cup and a preparation method thereof. The plastic cup comprises the following components in parts by weight: 60-80 parts of polypropylene, 3-8 parts of polyformaldehyde, 5-15 parts of modified nano calcium carbonate, 3-5 parts of kaolin, 2-4 parts of talcum powder, 0.2-0.4 part of a nucleating agent, 0.5-1.5 parts of a lubricant, 1-3 parts of an antioxidant and 0.5-1.0 part of a stabilizer. The preparation method comprises the following steps: uniformly stirring polypropylene, polyformaldehyde, modified nano calcium carbonate, kaolin, talcum powder, a nucleating agent, a lubricant, an antioxidant and a stabilizer to obtain a mixture; the mixture is subjected to melt extrusion, granulation and injection molding to obtain the plastic cup, and the plastic cup not only has excellent mechanical properties, but also has excellent antibacterial properties, and can effectively prevent growth of bacteria.
Owner:YANCHENG HUIDA BIOTECHNOLOGY CO LTD

Antibacterial PP material and preparation method thereof

InactiveCN119264554Aaccelerated deathExtended service lifeCarbon layerActive agent
The invention relates to an antibacterial PP material and a preparation method thereof, and belongs to the technical field of high polymer materials. The antibacterial PP material is prepared from the following components in parts by weight: 60 to 80 parts of PP resin, 2 to 4 parts of a surfactant, 0.5 to 1.5 parts of a modified antibacterial agent, 0.5 to 1.5 parts of a flame retardant and 0.2 to 0.8 part of an antioxidant, titanium ions in the modified antibacterial agent destroy bacterial cell walls, quaternized intermediate products react with proteins of cell membranes to accelerate bacterial death, and in addition, phenolic hydroxyl groups absorb ultraviolet rays with different wavelengths to inhibit the light aging process; a compact and continuous carbon layer is formed during combustion of the flame retardant and cooperates with phosphorus-oxygen double bonds and melamine, the flame retardant efficiency is improved, aluminum hydroxide coats the surface, hydroxyl is subjected to heat absorption decomposition during combustion, the surface temperature of combustible materials is stabilized, meanwhile, an inert aluminum oxide layer is formed, and the flammability is reduced. The antibacterial PP material prepared by the invention not only has good antibacterial and anti-aging effects, but also has excellent flame retardant property.
Owner:DONGGUAN AURORA BIOTECHNOLOGY CO LTD

High-performance photocatalytic metal organic framework antibacterial material as well as preparation method and application thereof

The invention belongs to the technical field of metal organic frameworks, and particularly relates to a high-performance photocatalytic metal organic framework antibacterial material as well as a preparation method and application thereof. The preparation method comprises the following steps of: growing a metal organic framework UiO 66 which takes a cerium element as a metal node on a single-layer graphene oxide UiO66 (at) GO in situ, loading arginine small molecules in the MOF framework to obtain a high-performance photocatalytic MOF antibacterial material UiO66 (at) GO (at) arg, forming a nano hydrogel with a stable three-dimensional structure with chitosan, and performing antibacterial treatment by using the nano hydrogel as a wound dressing. The Ce-based MOF composite QCS / GO-UiO 66-coated arg / PNIPAm hydrogel prepared by the preparation method disclosed by the invention has excellent properties such as elasticity, adhesive power, water absorption and biocompatibility; and under illumination, the photocatalyst has an excellent photocatalytic sterilization effect, and has a good killing effect on escherichia coli and staphylococcus aureus.
Owner:GUANGZHOU MEDICAL UNIV

Micromolecular antibacterial polypeptide, and preparation method therefor and use thereof

The present disclosure relates to the technical field of antibacterial drugs, and specifically relates to a micromolecular antibacterial polypeptide, and a preparation method therefor and the use thereof. The antibacterial peptide provided in the present disclosure has a stronger antibacterial activity compared with most other derived polypeptides and the antibacterial polypeptides disclosed in the existing reports. Bactericidal activity evaluation is carried out by using a plurality of strains known to have drug resistance, and the results show that the antibacterial peptide provided in the present disclosure has broad-spectrum antibacterial activity against drug-resistant strains and more comprehensive antibacterial effects, and allows for wider indications.
Owner:SHENZHEN ICARBONX INTELLIGENT PEPTIDE PHARM TECH CO LTD

Targeting BamA antibacterial peptide as well as preparation method and application thereof

The invention discloses a BamA-targeting antibacterial peptide as well as a preparation method and application thereof, and is characterized in that amino acids in a sequence are all D-type amino acids, and the amino acid sequence is as follows: w-r-r-w-r-r-p-w-k-r (dTrp-dArg-dArg-dTrp-dArg-dArg-dPro-dTrp-dLys-dArg). The antibacterial peptide provided by the invention has good antibacterial activity, can be synthesized by adopting an Fmoc solid-phase chemical method, is low in preparation difficulty, and has high affinity with target protein BamA.
Owner:CHONGQING UNIV OF TECH +1

High-strength antibacterial polypropylene plastic and preparation method thereof

InactiveCN120005322AFiberPolymer science
The invention relates to the technical field of polypropylene plastics, in particular to a high-strength antibacterial polypropylene plastic and a preparation method thereof. The antibacterial polypropylene material comprises the following components in parts by weight: 60-80 parts of polypropylene resin, 5-15 parts of nano titanium dioxide and nano zinc oxide composite particles modified by a special organosilicon polymer, 3-8 parts of an antibacterial agent compounded by quaternary ammonium salt and bioactive peptide, 5-10 parts of a core-shell structure MBS toughening agent and 0.5-2 parts of a hindered phenol-thioether composite antioxidant. 1-3 parts of a calcium stearate processing aid; and 3-8 parts of dopamine modified chopped carbon fibers. The composite material is high in strength, tensile strength, bending strength and impact strength are remarkably improved, and larger external force can be borne; the antibacterial performance is excellent, and the antibacterial rate reaches 95%-99%; the preparation process is environment-friendly and efficient, and the product is good in stability and recoverable; product safety can be guaranteed, the service life is prolonged, and economic and social benefits are good.
Owner:GUANGDONG SUN XIAOMEI SMART HOME TECH CO LTD

Preparation process of coating for improving antibacterial and corrosion-resistant performance of wood

The invention relates to the technical field of wood corrosion prevention and corrosion resistance treatment, in particular to a preparation process of a coating for improving the antibacterial and corrosion-resistant performance of wood. In order to improve the antibacterial and corrosion-resistant capabilities of the prepared coating, a corrosion-resistant antibacterial agent is prepared and added into the raw materials of the coating, and quaternary ammonium salt, guanidyl and other group structures are introduced into the corrosion-resistant antibacterial agent, so that the antibacterial performance on microorganisms such as fungi is realized; the introduction of fluorine can effectively improve the hydrophobicity of a coating of the paint and reduce the influence of water vapor on antibacterial components in the coating, and the introduction of allyl can enable the corrosion-resistant antibacterial agent to react with butyl acrylate and other raw materials under the action of an initiator to achieve the cross-linking ability, so that the loss of the corrosion-resistant antibacterial agent is effectively avoided, and the service life of the coating is prolonged. The antibacterial activity is kept for a long time.
Owner:JIANGSU YIJING TECH CO LTD

Porphyrin copper ion covalent organic framework material with excellent biocompatibility

The invention discloses a porphyrin copper ion covalent organic framework material with excellent biocompatibility, and belongs to the technical field of biological medicines. The porphyrin copper ion covalent organic framework material is obtained by carrying out solvothermal reaction copolymerization on a porphyrin compound and a novel copper Schiff base boric acid complex in a protective atmosphere; the porphyrin compound is 5, 10, 15, 20-tetra (3, 4-dihydroxyphenyl) porphyrin, and the structural formula of the porphyrin compound is shown in the specification. The structural formula of the novel copper Schiff base boric acid complex is # imgabs0 #. According to the invention, a novel copper Schiff base complex and 5, 10, 15, 20-tetra (3, 4-dihydroxyphenyl) porphyrin are copolymerized to obtain Cu-COF with negligible biotoxicity, and the material realizes the synergistic effect of three antibacterial modes of PDT, PTT and hydroxyl free radicals. The prepared Cu-COF can also be slowly degraded in an acid environment, the infected microenvironment is improved in the degradation process, and the antibacterial effect is improved.
Owner:WEIFANG MEDICAL UNIV

Absorbable suture line for surgical suture and preparation method thereof

The invention discloses an absorbable suture line for surgical suture and a preparation method thereof, and relates to the technical field of medical materials. The absorbable suture line for surgical suture is prepared from the following raw materials in parts by weight: 50 to 65 parts of polylactic acid, 15 to 20 parts of polyglycolic acid, 3 to 5 parts of sodium carboxymethyl cellulose, 3 to 8 parts of a toughening agent, 3 to 6 parts of an antibacterial agent, 0.3 to 0.8 part of a lubricating agent, 1 to 2 parts of sodium hyaluronate and 5 to 10 parts of polyvinyl alcohol. The toughening agent is obtained by reacting hydroxyethyl acrylate with ethylenediamine to generate a four-arm compound and then reacting with 6-caprolactone and DL-lactide. The absorbable suture line for surgical suture prepared by the invention has excellent tensile property and antibacterial property, and can meet the application requirements of clinical medical treatment.
Owner:HUBEI SHUANGXING PHARMA CO LTD

Degradable environment-friendly packaging material and preparation process thereof

The invention provides a degradable environment-friendly packaging material and a preparation process thereof, and belongs to the technical field of packaging materials. The preparation method comprises the following steps: preparing the modified nano montmorillonite; preparing a composite antibacterial additive; preparing a barrier additive; and preparing the degradable environment-friendly packaging material. The preparation method comprises the following steps: by taking methacrylic acid (2-dimethylaminoethyl) ester and acrylic acid as raw materials, modifying nano-montmorillonite under the initiation of benzoyl peroxide, performing quaternary ammonium salinization, and performing in-situ synthesis of nano-zinc oxide on the surface of the quaternary ammonium salinized montmorillonite through a hydrothermal reaction to prepare the composite antibacterial additive. When the composite antibacterial additive is added into polylactic acid to prepare a packaging material, the growth of various microorganisms such as bacteria and fungi can be effectively inhibited, the packaging material is endowed with strong antibacterial protection capability, and the composite antibacterial additive has a more lasting antibacterial effect so as to prolong the antibacterial validity period of the packaging material.
Owner:SHANDONG DEYU TIANHONG NEW MATERIAL TECH CO LTD

Preparation and application of cubilose glycopeptide for prevention and adjuvant therapy of gynecological inflammation and gastrointestinal inflammation

The invention relates to the field of cubilose peptides, in particular to preparation and application of cubilose glycopeptides capable of preventing and assisting in treating gynecological inflammation and gastrointestinal inflammation. The invention provides cubilose glycopeptide which comprises cubilose peptide, sialylated O-glycan and sialylated N-glycan, and the cubilose peptide is connected with the sialylated O-glycan and / or the sialylated N-glycan. The cubilose glycopeptide provided by the invention has unique sialylated O-glycans and N-glycans, has unique biological activity and functions and synergistic effect compared with the cubilose glycopeptide without N-glycans or O-glycans and non-sialylated cubilose peptides, and forms and enhances the inhibition effect on pathogens and the antiviral effect; therefore, the compound has unique advantages in the aspect of preventing and treating related problems. The sialic acid binding type cubilose glycopeptide has stronger antibacterial activity, especially has an inhibition effect on pathogens such as candida albicans and helicobacter pylori, and also has an antiviral effect.
Owner:XIAMEN YAN PALACE SEELONG BIOTECHNOLOGY CO LTD

Bio-based adhesive and preparation method thereof

The invention provides a bio-based adhesive and a preparation method thereof. Inspired by a spider thread structure, biomass adhesive interface enhancement based on a tannic acid adhesion group is combined with construction of a differential phase separation structure by biomass-induced polylipoic acid depolymerization, and a brand new strategy of adhesion-cohesion synergistic enhancement of the adhesive strength of the adhesive is realized. According to the invention, tannic acid and carboxymethyl chitosan are introduced into a lipoic acid-based adhesive, so that the purpose of synergistically enhancing the bonding performance of the adhesive through adhesion-cohesion is achieved, and the defects of weak cohesion, low bonding strength, poor water resistance, poor moisture resistance and the like of the conventional biomass adhesive are overcome. Benefited from a new strategy of adhesion-cohesion synergistic enhancement, the biomass adhesive has good adhesive strength in various environments and materials. In addition, the biomass adhesive also has the characteristics of biological safety, antibacterial and mildew-proof properties and recoverability, so that the product has wider application and potential compared with the previous product, and has a good application prospect.
Owner:GUANGXI UNIV