6534 results about "Anti bacterial" patented technology

The invention discloses a metal-doped carbon quantum dot as well as preparation and application of the metal-doped carbon quantum dot in a nano antibacterial agent, citric acid, urea and tea polyphenol are taken as precursors, metal salt is added, carbon dot synthesis and metal ion doping are synchronously completed in one step through a hydrothermal method, and the metal-doped carbon quantum dot is prepared; the surfaces of the metal-doped carbon quantum dots are negatively charged, and the metal-doped carbon quantum dots have peroxidase-like activity and catalase-like activity at the same time; the metal ions adopt any one of Fe < 3 + >, Cu < 2 + > and Ce < 3 + >; the metal-doped carbon quantum dots are in a sphere-like shape. The metal-doped carbon quantum dots prepared by the preparation method disclosed by the invention have peroxidase-like activity and catalase-like activity at the same time through precise doping of metal ions, and the two activities have a synergistic effect in an oral periodontitis microenvironment, so that a good antibacterial effect is achieved.

The invention relates to the technical field of antibacterial and antifouling fabrics, provides a preparation method of an antibacterial and antifouling fabric, and solves the problem of poor fabric durability caused by single functional component and lack of physical protection in the prior art. The preparation method comprises the following steps: S1, preparing MOFs loaded antibacterial fibers: blending a metal organic framework antibacterial composite nanomaterial and a polymer matrix material, and carrying out melt spinning to prepare the MOFs loaded antibacterial fibers; s2, constructing a self-cleaning functional coating: dispersing the fluorinated nanoparticles and a polymer adhesive in a solvent to prepare a self-cleaning coating solution; s2, performing surface activation treatment on the MOFs-loaded antibacterial fiber obtained in the step S1, soaking the MOFs-loaded antibacterial fiber in the self-cleaning coating liquid, and performing pulling and curing to form a bionic micro-nano structure coating on the surface of the MOFs-loaded antibacterial fiber so as to obtain a functional composite fiber; s3, spinning forming: taking the functional composite fibers obtained in the step S2 as warp yarns and / or weft yarns, and weaving to obtain the antibacterial and antifouling fabric.

A male cap can include a male tapered outer surface that can be configured to mate with a female luer to create a fluid tight fit. The male cap can also include a water-soluble antimicrobial composition disposed on the male extension. The male cap can include a fluid-soluble, slower-dissolving material covering the water-soluble antimicrobial composition or incorporated within the water-soluble antimicrobial composition. The slower-dissolving material can be configured to slow a dissolution of the water-soluble antimicrobial composition during installation of the male cap into the female luer.

The invention relates to a novel application of animal bifidobacterium subsp. Lactis BGI-N3, in particular to an application of the animal bifidobacterium subsp. Lactis BGI-N3 in preparation of a preparation for relieving skin allergy. The invention finds that the bifidobacterium animalis subsp. Lactis BGI-N3 has a very remarkable effect in the aspect of relieving skin allergy, and the effect is specifically shown as follows: in an atopic dermatitis animal model, the dermatitis score, scratching times and percutaneous water loss are remarkably reduced, and the atopic dermatitis skin tissue damage condition is relieved; the immune organ edema condition is improved, the levels of Th2 type cell factors and inflammatory factors IL-6, TNF-alpha and IFN-gamma related to dermatitis are reduced, and the immune balance of the body is recovered; expression of fibroin and endothelial protein in skin tissue is improved, and the skin barrier is repaired; the level of antibacterial peptide in skin tissues is recovered, and the antibacterial activity of the skin is enhanced. Meanwhile, compared with a traditional chemical medicine for treating atopic dermatitis, the animal bifidobacterium subsp. Lactis BGI-N3 has no side effects such as weight loss, immune organ atrophy, immune imbalance and the like.

The invention relates to the technical field of medical dressings, in particular to a perianal drug dressing of a multi-layer flow guide composite fabric and a preparation method and application of the perianal drug dressing of the multi-layer flow guide composite fabric. The perianal drug dressing is of a four-layer structure, a wet tissue adhesion layer is made of polydopamine modified chitosan / oxidized hyaluronic acid hydrogel, and wet-state adhesion is achieved; the drug sustained-release layer is used for dispersing mesoporous silica loaded with ciprofloxacin hydrochloride / defensin and chitosan microspheres loaded with epidermal growth factors / lonicera japonica into a polycaprolactone fiber membrane to achieve synergistic antibacterial and healing promotion; the directional flow guide layer is of a gradient wettability sandwich structure with a bionic micro-channel, and one-way rapid drainage can be achieved; the high-absorption outer layer is carboxymethyl cellulose / sodium polyacrylate composite sponge, liquid is locked efficiently, the wound surface is kept dry and comfortable, the clinical problem in perianal infection wound treatment can be effectively solved, and the treatment effect and the patient comfort are remarkably improved.

The invention discloses a macrocyclic covalent organic polymer material for inhibiting a pi-pi stacking effect and application of the macrocyclic covalent organic polymer material, and belongs to the technical field of biological medicines. The preparation method comprises the following steps: adding 5, 10, 15, 20-tetra (4-ethynylphenyl) copper porphyrin and a macrocyclic monomer into an organic solvent in a protective atmosphere, and carrying out solvothermal reaction in the presence of a catalyst and alkali to obtain the macrocyclic covalent organic polymer material. According to the invention, 5, 10, 15, 20-tetra (4-ethynylphenyl) copper porphyrin and a macrocyclic monomer form a porous polymer MCP-CU-POP, the material utilizes the photo-thermal capability to combine the effects of simulated photo-thermal (PTT), photodynamic (PDT), peroxidase (PODs) and glutathione peroxidase (GSH-Px) to perform synergistic antibiosis, and the inherent characteristics of an infected microenvironment can also be utilized to induce death of bacteria, so that the antibacterial property of the material is greatly improved, and the antibacterial property of the material is greatly improved. And the microenvironment of the bacterial infection part can be adjusted, so that the recovery of the bacterial infection wound can be obviously accelerated.

The invention discloses an antibacterial peptide based on D-type amino acid and application of the antibacterial peptide, and the antibacterial peptide is characterized in that the amino acid sequence is w-r-r-w-r-r-w-w-r-k-r (dTrp-dArg-dArg-dTrp-dArg-dArg-dTrp-dTrp-dArg-dLys-dArg). The antibacterial peptide can be synthesized through an Fmoc solid-phase chemical method, the synthesis difficulty is low, and the in-vivo antibacterial activity is good. The antibacterial peptide especially has broad-spectrum killing activity on carbapenem-resistant pseudomonas aeruginosa, pseudomonas aeruginosa, klebsiella pneumoniae, escherichia coli, methicillin-resistant staphylococcus aureus and staphylococcus aureus, is low in hemolytic toxicity, can reach half or more of cell survival rate under medium and low concentration, almost has no toxic effect on cells, and can be used for preparing the antibacterial peptide with a broad-spectrum killing activity on carbapenem-resistant pseudomonas aeruginosa, klebsiella pneumoniae, escherichia coli, methicillin-resistant staphylococcus aureus and staphylococcus aureus. The stability is good, the operability is high, and the cost is low.

The invention relates to the technical field of biomedical materials, in particular to a metal-loaded antibacterial agent and a preparation method thereof.The preparation method comprises the following steps that a metal precursor is loaded to the surface of a carrier, and then washing and drying are conducted; and carrying out mechanical ball milling on the dried sample by using a planetary ball mill, carrying out in-situ roasting in the mechanical ball milling process, cooling to room temperature, washing with water, and drying to obtain the metal-loaded antibacterial agent. According to the preparation method, the regulation and control on the interaction between the metal and the carrier can be realized by utilizing mechanical ball milling, the interaction between the metal and the carrier in the prepared antibacterial agent is stronger than that of a sample prepared by an impregnation method, and the regulation and control on the interaction between the metal and the carrier can be realized by changing parameters of a ball milling process; and meanwhile, by regulating and controlling the interaction strength of the'metal-carrier ', the controllable slow release of metal ions can be realized, the antibacterial effect is ensured, and the action duration of the medicine is prolonged.

The invention discloses a dual-mechanism antibacterial photosensitizer as well as a preparation method and application thereof, and relates to the technical field of biomedical photoelectric functional materials. The invention relates to a triphenylamine derivative, which can realize fluorescence imaging of bacterial or fungal infection by utilizing fluorescence characteristics, can generate active oxygen under illumination to play a photodynamic therapy role, is suitable for preparing photodynamic therapy preparations and developing antibacterial materials, and can also be applied to the fields of environment and public health and tumor treatment. The problems that an existing photosensitizer is insufficient in broad spectrum, different in fungus drug resistance mechanism, limited in single treatment effect and the like can be effectively solved, and the photosensitizer has wide application prospects.

The invention provides a hydroxytyrosol supramolecular compound and a preparation method and application thereof, and belongs to the technical field of cosmetics and biological medicine, the supramolecular compound comprises the following chemical components by mass: 0.01-10% of hydroxytyrosol, 2-45% of an amino acid compound, 2-20% of alpha hydroxy acid, 2-30% of urea, and 15-92% of water. The supramolecular compound can promote transdermal delivery of hydroxytyrosol and maintain the biological activity of hydroxytyrosol, shows high biocompatibility, and can be applied to product development in the antibacterial field, the regeneration field and the anti-aging field.

The invention relates to the technical field of food packaging materials, in particular to a cerium dioxide nano-enzyme modified antibacterial coating and application of the cerium dioxide nano-enzyme modified antibacterial coating in food packaging. The biomimetic mineralization layer comprises the following components in percentage by weight: 35-45% of a green base material, 8-12% of dopamine modified yttrium-doped cerium dioxide nano-enzyme, 4-6% of a composite antibacterial agent, 3-4% of a natural cross-linking agent, 2-3% of a degradable plasticizer, 1-2% of a biomimetic mineralization layer precursor and the balance of deionized water, the green base material is a blend of a chitosan-polyethylene glycol graft and polylactic acid; the doping amount of Y3 in the nano enzyme is 3-4at%. The antibacterial agent is excellent and lasting in antibacterial effect, has no migration risk of the antibacterial agent, and can guarantee food safety; a green base material and a degradable plasticizer are adopted, so that natural degradation is realized, and environmental pollution is avoided; the mechanical property is good, the aging resistance is realized, and the oxygen barrier property is strong; the food packaging box is suitable for various foods, effectively prolongs the shelf life, and meets the requirement of green packaging.

The invention belongs to the technical field of textile, and relates to an efficient antibacterial fabric for preparing underwear and a dyeing and finishing method and application thereof.The provided antibacterial fabric is weft-knitted bird eye double-faced knitted fabric and is composed of polyester, cotton and modal fibers, the surface density is 180 g / m, surface yarn of the antibacterial fabric is hollow polyester fibers with special-shaped sections, and the surface yarn of the antibacterial fabric is hollow polyester fibers with special-shaped sections. The lining yarn is formed by weaving dacron and blended yarn according to the proportion of 2: 1. According to the method, dyeing and finishing of the antibacterial fabric, fabric weaving and ergonomic sewing are combined, the fabric which has efficient antibacterial performance, good moisture permeability and ultraviolet-proof performance and high color fastness is obtained, and the prepared antibacterial clothes are high in quick-drying performance, comfortable to wear and high in environmental adaptability.

The invention discloses injectable hydrogel for photo-thermal adjuvant therapy of periodontitis and a preparation method, and belongs to the technical field of high polymer material preparation, the preparation method comprises the following steps: reacting MXene dispersion liquid with epigallocatechin gallate and MgSO4; then sequentially carrying out ultrasonic treatment, centrifugation, washing and freeze-drying to obtain a multifunctional nanosheet MP-Mg; adding the multifunctional nanosheet MP-Mg into an oxidized gellan gum aqueous solution, and carrying out a mixed reaction to obtain a solution A; mixing the quaternary ammonium salt chitosan aqueous solution and the carboxymethyl chitosan aqueous solution in equal volume, and reacting to obtain a solution B; and mixing the solution A and the solution B in equal volume for reaction. The hydrogel prepared by the preparation method disclosed by the invention has injectability, photo-thermal responsiveness, biological membrane penetrability, synergistic antibacterial property and long-acting anti-inflammatory property, and an innovative and practical photo-thermal adjuvant therapy platform is provided for clinical treatment of periodontitis.

The invention discloses an antibacterial peptide fragment intercepted from chitinase IDGF4 protein and application of the antibacterial peptide fragment in preparation of antibacterial drugs. According to the invention, short peptide fragments in chitinase IDGF4 protein are screened, three candidate peptides are obtained through chemical synthesis, the antibacterial performance of the candidate peptides is systematically evaluated, and the evaluation result shows that the peptide fragment with the amino acid sequence as shown in SEQ ID No.2 can effectively inhibit the growth of salmonella and staphylococcus aureus under the concentration of 1mg / mL; the antibacterial effect of the compound is confirmed in inhibition zone experiments, enzyme-labeled turbidimetry and growth curve monitoring, and the compound shows stable and remarkable antibacterial activity and can be used as a novel antibacterial molecule; the invention provides a new candidate sequence for developing the antibacterial peptide with high efficiency and low drug resistance risk, and has application potential in the aspect of preparing clinical antibacterial drugs.

The invention relates to the technical field of ceramic materials, and discloses antibacterial self-cleaning domestic ceramic and a preparation method thereof. The preparation method comprises the following steps: S1, mixing a ceramic green body raw material, an antibacterial precursor and an auxiliary agent, performing ball milling to obtain slurry, performing slip casting on the slurry to obtain a green body, and drying to obtain the green body; s2, carrying out gradient in-situ reaction sintering on the green body, and sintering at the temperature of 400-600 DEG C; then sintering at the temperature of 800 to 1000 DEG C; then sintering at the temperature of 1100 to 1250 DEG C; s3, after sintering, micron-sized pits are formed in the surface of the ceramic body through plasma etching; and S4, glazing: sintering at 700-900 DEG C to combine the glaze with the biscuit, thereby obtaining the antibacterial self-cleaning domestic ceramic. The preparation process is simple, long-acting synergism of antibacterial and self-cleaning performance is achieved, and firm combination of the functional layer and the ceramic matrix is achieved.

The invention discloses an implant-derived exosome which is prepared by the following steps: adding cleaned and crushed colored rice flour into a PBS (Phosphate Buffer Solution) with the pH value of 6-7.4, homogenizing at a high speed, adding alpha-amylase into rice milk, performing enzymolysis for 1-2 hours under the conditions that the pH value is 6-7.4 and the temperature is 90-97 DEG C, filtering, and standing filtrate overnight; carrying out gradient differential centrifugation at 4 DEG C, collecting supernate, filtering, carrying out ultracentrifugation on filtrate at 4 DEG C and 12000-15000g for 1.5-3 hours, and collecting precipitate; and re-suspending the precipitate, enriching by using an MWCO ultrafiltration tube with the molecular weight cut-off of 100kDa, collecting the precipitate at the bottom of the ultrafiltration tube, and re-suspending in a PBS buffer solution, thereby obtaining the product. The exosome can effectively inhibit the generation of inflammatory factors, has a good inhibition effect on various pathogenic bacteria, also has an anti-oxidation effect, and has application prospects in the fields of inflammation resistance, bacteria resistance, oxidation resistance and the like.

The invention relates to the field of oral cavities, and particularly discloses a lasting antibacterial type composite tooth socket for medicine carrying and a preparation method thereof.The lasting antibacterial type composite tooth socket comprises an adsorption layer and an antibacterial membrane layer, the adsorption layer is used for adsorbing oral cavity treatment liquid medicine, and the antibacterial membrane layer comprises a nano-silver antibacterial layer and a chitosan antibacterial layer; the preparation method comprises the following steps: mixing a tea polyphenol-polylactic acid composite solution, a nano-silver-carboxylation modified cellulose compound and a polyvinyl alcohol solution, and carrying out electrostatic spinning to prepare a nano-silver antibacterial fiber membrane, so as to form the nano-silver antibacterial layer; mixing chitosan with hot water, adding cinnamyl aldehyde, glycerol and boric acid, stirring to obtain a mixed solution, coating one side of the nano-silver antibacterial layer with the mixed solution, and curing to form a chitosan antibacterial layer; the adsorption layer is attached to the side, away from the chitosan antibacterial layer, of the nano-silver antibacterial layer, and then the lasting antibacterial type composite tooth socket for carrying the medicine is prepared through hot-pressing compounding. The drug-loaded composite tooth socket has the characteristic of further improving the antibacterial property and the antibacterial durability of the drug-loaded composite tooth socket.

The invention relates to a metallized microbubble and a preparation method thereof, a construction method of a multifunctional composite probe, and a rapid bacterium capturing and sterilizing method, and belongs to the technical field of functional material preparation. The method aims at solving the technical problems that in the prior art, a metal coating on the surface of the hollow glass microbubble is not uniform, combination is not firm, and stability is poor. According to the technical scheme, the method is characterized by comprising the following steps: mixing surface-activated hollow glass microbubbles with a polyethyleneimine solution for reaction, and washing and drying to obtain polyethyleneimine-coated hollow glass microbubbles; then reacting with a single-stranded DNA buffer solution to obtain an intermediate product loaded with DNA; then introducing a silver nitrate solution to load silver ions on the surface of the compound; and finally, reducing through a sodium borohydride solution to prepare the metallized microbubbles. The metalized microbubbles prepared by the method can be used for constructing a multifunctional composite probe to realize efficient capture and synergistic antibiosis of targets such as bacteria.

The invention discloses a high-activity injectable self-healing temperature-sensitive hydrogel dressing and a preparation method and application thereof, the high-activity injectable self-healing temperature-sensitive hydrogel dressing is obtained by forming a temperature-sensitive hydrogel through a two-dimensional nano material MXene aqueous solution and F127 under the hydrogen-bond interaction, combining an M2 macrophage source exosome on MXene under the electrostatic adsorption action, and wrapping the MXene through a network structure of the hydrogel. The preparation method is simple, an obtained sample is free of organic solution residues, reaction conditions are mild, operation is convenient, the raw material cost is low, the hydrogel dressing has temperature-sensitive, injectable and self-healing performance, the hydrogel dressing has temperature-sensitive and injectable performance, is sol at normal temperature, forms gel after making contact with skin and is convenient to smear and use on wounds, and experimental results prove that the hydrogel dressing has good application prospects. The hydrogel has good biocompatibility and relatively strong antibacterial performance, and can effectively play anti-inflammatory and vascular regeneration promoting roles in diabetic wounds and promote rapid repair of the diabetic wounds.

The invention discloses a composition for regulating scalp micro-ecology and application thereof, and relates to the technical field of daily chemical products. The composition for regulating scalp micro-ecology comprises the following components: emu oil, melaleuca alternifolia leaf oil, Brazil green propolis and hydrogenated castor oil. The invention provides a composition for regulating scalp microecology and application thereof, the composition is prepared by compounding an anti-inflammatory and antibacterial component emu oil with melaleuca alternifolia leaf oil, Brazilian green propolis and hydrogenated castor oil, the composition has synergistic bacteriostasis and anti-inflammation effects, keeps scalp microbe balance, reduces red and swollen skin and itching, and also can promote the regeneration capacity of skin tissue cells.

The invention relates to the technical field of reverse osmosis membranes, in particular to a multilayer composite anti-biological-pollution reverse osmosis membrane and a preparation method thereof. The reverse osmosis membrane is prepared by the method. The method comprises the following steps: immersing a base membrane into a prepared water phase solution, and sequentially carrying out first immersion treatment and drying treatment in the shade to obtain a first membrane sheet; immersing the first membrane into a prepared organic phase solution, removing the redundant organic phase solution on the first membrane after second immersion treatment, and obtaining a second membrane after interface reaction; and immersing the second membrane into a prepared antibacterial metal ion solution, and carrying out complexation reaction to obtain the multi-layer composite anti-biological-pollution reverse osmosis membrane. According to the invention, the multilayer composite anti-biological pollution reverse osmosis membrane with prolonged antibacterial activity and improved membrane separation performance can be prepared.

The invention discloses lysozyme, antibacterial peptide derived from the lysozyme and application of the lysozyme in preparation of antibacterial drugs. According to the invention, 1, 640 protein sequences recorded in a ruminant rumen caterpillars genome database are systematically predicted based on a lysozyme prediction model, and finally, the lysozyme with the amino acid sequence as shown in SEQ ID No.1 is relatively strong in antibacterial activity and stable in antibacterial activity, and is slightly influenced by environmental factors. According to the invention, an antibacterial peptide region of the lysozyme is analyzed and determined, three peptide fragments with clear antibacterial activity are identified, and the amino acid sequences of the peptide fragments are respectively shown as SEQ ID No.2, SEQ ID No.3 or SEQ ID No.4. The antibacterial peptide provided by the invention has relatively strong membrane destroying ability and broad-spectrum antibacterial activity, and compared with integral protein, the antibacterial peptide is simpler in structure and more flexible in synthesis and modification, and is easier to break through a bacterial drug-resistant mechanism.

The invention belongs to the technical field of polypeptides and biological medicines, and particularly relates to a WK7 series antibacterial peptide and application thereof in the aspects of resisting bacteria and preventing and treating diabetic foot, pneumonia and septicemia. According to the invention, a linear peptide WK7-line with an amino acid sequence of WKRWKRW is used as a minimum active unit, and modification is carried out to form a plurality of linear modified peptides; meanwhile, a cyclic peptide WK7-cyl is formed on the basis of the linear peptide WK7-line through cyclization, and the cyclic peptide WK7-cyl is further modified to form an annular modified peptide. The linear peptide WK7-line, the linear modified peptide, the cyclic peptide WK7-cyl and the cyclic modified peptide jointly form the WK7-series antibacterial peptide, and the WK7-series antibacterial peptide is artificially synthesized polypeptide, is small in molecular weight, easy to synthesize, free of cytotoxicity, almost free of hemolysis risk, high in sterilization speed and broad-spectrum antibacterial property and can be used for preparing the antibacterial peptide. The traditional Chinese medicine composition has a certain effect on prevention and treatment of diabetic foot ulcer, pneumonia and septicemia.

The invention provides a composite hydrogel for infectious bone defect repair and a preparation method thereof, and belongs to the technical field of bone defect repair, the composite hydrogel comprises a three-dimensional porous network structure hydrogel and a bioactive unit, and the bioactive unit is loaded in the three-dimensional porous network structure hydrogel; the hydrogel with the three-dimensional porous network structure is prepared from photo-crosslinked methacrylated silk fibroin and nano-hydroxyapatite; the bioactive unit comprises a strontium metal organic framework loaded with curcumin. According to the invention, the photo-crosslinked methacrylated silk fibroin provides excellent biocompatibility; as an ion / drug dual carrier, the strontium metal organic framework can continuously release strontium ions and bidirectionally regulate bone metabolism (promoting osteogenesis and inhibiting osteoclast), and the porous structure of the strontium metal organic framework can efficiently load a hydrophobic drug curcumin (Cur). Curcumin has strong antibacterial and anti-inflammatory functions; the nano-hydroxyapatite can obviously enhance the mechanical strength of the hydrogel.

The invention belongs to the technical field of antibacterial peptides, and particularly relates to an antibacterial peptide Mh-GC21 as well as a precursor and application thereof. The amino acid sequence of the antibacterial peptide Mh-GC21 provided by the invention is as shown in SEQ ID NO.1, and two cysteines are oxidized to form a pair of intermolecular disulfide bonds; the C tail end of the antibacterial peptide Mh-GC21 is subjected to amidation modification. The antibacterial peptide Mh-GC21 provided by the invention is from microhyla microcarpa, has broad-spectrum antibacterial activity, has relatively good antibacterial and bactericidal effects on standard strains of acinetobacter baumannii, escherichia coli and staphylococcus aureus and clinically sourced drug-resistant strains, and can be used for targeted destruction of cell membranes of bacteria, removal of biological membranes and inhibition of formation of the biological membranes. Moreover, the antibacterial peptide Mh-GC21 has the advantages of good stability, no hemolytic activity and cytotoxicity, and difficulty in inducing strains to generate drug resistance.

The invention relates to the technical field of functional fiber materials, in particular to a fiber material with an antibacterial function and a preparation method thereof, and the preparation method comprises the following steps: S1, preparing composite antibacterial powder; s2, preparing antibacterial functional particles; s3, preparing a spinning solution; s4, performing wet spinning and post-treatment to obtain the fiber material with the antibacterial function. A triple antibacterial system is formed by constructing the ferroferric oxide core body, the zinc oxide middle layer and the chitosan shell and is fused into the fiber preparation process, and the fiber material which is excellent in antibacterial effect, resistant to washing and good in environmental adaptability and has the antibacterial function is obtained.

The invention discloses an antibacterial breathable dressing patch and a preparation method thereof, and belongs to the field of medical dressings, the antibacterial breathable dressing patch comprises a Janus type dressing patch layer which is a composite film containing a hydrocolloid matrix, pH response antibacterial microspheres and bioactive glass nanoparticles; the super-hydrophobic electrostatic spinning outer layer is a super-hydrophobic electrostatic spinning fiber membrane, and the super-hydrophobic electrostatic spinning outer layer and the Janus type dressing skin-attaching layer are compounded to form an asymmetric Janus structure, intellectualization and precision of the antibacterial effect are achieved, and the risks of cytotoxicity and bacterial drug resistance possibly caused by long-term exposure to an antibacterial agent are reduced to the maximum extent; a multi-mechanism and synergistic antibacterial defense system is constructed, more comprehensive and firm protection is provided for wounds, the air permeability and moisture permeability are excellent, a dry and moist ideal healing environment is created for the wounds, the biocompatibility is good, the use safety is high, the wound healing agent is mild to human tissues, the irritation is low, the allergic reaction risk is small, the safety is high, and the wound healing effect is good. The long-term use is facilitated.

The invention provides dust-free antibacterial deodorant bentonite cat litter and a preparation method thereof, and belongs to the technical field of cat litter. Firstly, a certain amount of sodium bentonite, baking soda and calcium carbonate are used for preparing bentonite cat litter, then polyvinyl alcohol and sodium carboxymethyl cellulose which have the film forming property, polyhexamethylene guanidine hydrochloride which has the bactericidal property and soybean ethyl sulfate morpholine which has the deodorization function are used for preparing the bentonite cat litter; the components are compounded to obtain a functional dust suppressant with antibacterial, deodorant and film-forming effects, the functional dust suppressant is sprayed and coated on the surface layer of the bentonite cat litter, so that the prepared dust-free antibacterial and deodorant bentonite cat litter is remarkable in deodorant and antibacterial effects and good in wear resistance, and a layer of water-soluble film is formed on the surface of the dust suppressant after the functional dust suppressant is sprayed for dust suppression treatment, so that the dust suppression effect is good. The bentonite cat litter has the advantages that the structure and the film-forming property of the surface layer of the bentonite cat litter are improved, the hardness and the wear resistance of the surface are improved, the dust suppression effect of the cat litter is obviously improved, dust is extremely low under simulated falling and transportation conditions, and the cat litter has excellent water absorption and caking performance.

The invention belongs to the technical field of antibacterial peptides, and particularly relates to an LL-37 derived antibacterial peptide and application thereof. According to the invention, 17-29aa of the LL-37 antibacterial peptide is used as a core fragment and is connected with an amino acid sequence shown as SEQ ID NO: 1 or SEQ ID NO: 2 through an amido bond, the antibacterial activity of the obtained antibacterial peptide is obviously higher than that of the LL-37 antibacterial peptide, and the antibacterial peptide shows an obvious bactericidal effect on clinical drug-resistant bacteria such as acinetobacter baumannii, pseudomonas aeruginosa, escherichia coli, staphylococcus aureus, klebsiella pneumoniae and the like; meanwhile, the cytotoxicity and hemolytic activity are weak, drug resistance is not prone to being generated, bacteria can be rapidly killed in vivo through multiple mechanisms, no obvious cytotoxicity exists, the bacterium load in tissue is remarkably reduced, and the lifetime of a bacterium-infected mouse is prolonged.

The invention provides an antibacterial hydrophilic polyester staple fiber and a preparation method thereof, and relates to the technical field of new textile materials, the antibacterial hydrophilic polyester staple fiber takes 1.56 dtex * 38mm polyester staple fiber as a basic specification, a melt direct spinning online adding technology is adopted, 2% of composite functional master batch is accurately added into a polyester melt, and the antibacterial hydrophilic polyester staple fiber is prepared. The master batch comprises a quaternary ammonium salt organic antibacterial agent and a hydrophilic modified polyester carrier grafted with polyethylene glycol (PEG), and spinning through a cross-shaped special-shaped spinneret plate, and combining with an optimized post-spinning process. The fiber has lasting antibacterial property and self-hydrophilic property, can meet the production requirements of high-end spunlace non-woven fabrics without after-treatment, and is particularly suitable for the fields of medical protection, health care and the like.