23results about How to "Change permeability" patented technology

The invention relates to the technical field of medical apparatus and instruments, in particular to a scar rehabilitation therapeutic apparatus for realizing treatment based on AI evaluation analysis, which comprises a host, an AI evaluation system and a magnetic treatment component, and is characterized in that the host comprises a shell and an electric control system; the AI evaluation system comprises a data acquisition module and a treatment planning module; the data acquisition module is used for acquiring human body scar area information, the treatment planning module identifies data acquired by the data acquisition module, scar information is obtained after the data are identified and processed, and a scar rehabilitation treatment scheme is planned according to the scar information; the electric control system controls the magnetic treatment assembly to perform scar rehabilitation treatment according to the scar rehabilitation treatment scheme; the magnetic treatment assembly comprises a magnetic fixing device, a magnetic driving device and a magnetic patch; the magnetic patch is attached to a human body scar area, and the magnetic driving device executes a scar rehabilitation treatment scheme under the control of the electric control system, so that the magnetic patch rotates and moves.

The invention relates to the technical field of polyurethane coatings, and discloses a preparation method of an antibacterial wear-resistant waterborne polyurethane coating, which comprises the following steps: taking concentrated hydrochloric acid, p-phenylenediamine, sodium nitrite, paraformaldehyde, amino-modified nano silicon dioxide and hexamethylene diisocyanate as raw materials; the preparation method comprises the following steps: taking 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide as a raw material, carrying out diazotization coupling reaction, substitution reaction, Mannich reaction and addition reaction to prepare modified polyisocyanate, then taking 9, 10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide and ((2-aminoethyl) azadiyl) dimethanol as raw materials, carrying out substitution reaction to prepare DOPO-based dihydric alcohol, and carrying out reaction to prepare the DOPO-based dihydric alcohol. Finally, the modified polyisocyanate, DOPO-based dihydric alcohol and polyethylene glycol 400 are used as raw materials, an antibacterial wear-resistant polyurethane emulsion is prepared through a prepolymerization reaction and a chain extension reaction, and the prepared polyurethane coating has good antibacterial, anti-ultraviolet, flame-retardant and wear-resistant properties.

The invention relates to the technical field of silica sol, and discloses a silica sol modified emulsion and a preparation method thereof.The preparation method comprises the steps that silica sol, an emulsifier SR-10, thiazole modified benzoxazine, sodium sulfonate modified thiazole and water are added into a reactor and stirred, and the silica sol modified emulsion is obtained after stirring is finished. Sulfur elements, nitrogen elements, silicon elements, benzoxazine structures and sodium sulfonate groups contained in thiazole modified benzoxazine and sodium sulfonate modified thiazole have good flame retardance; quaternary ammonium salts contained in thiazole modified benzoxazine and sodium sulfonate modified thiazole are adsorbed to the surfaces of thalli, and hydrophobic groups are inserted into lipoid layers, so that the permeability of cell membranes is changed, the membrane structure is destroyed, intracellular substances are leaked, bacterial death is caused, and a relatively good antibacterial effect is achieved.

The invention discloses an antibacterial plastic and a production process thereof.The antibacterial plastic is prepared from, by weight, 100-120 parts of linear low-density polyethylene and 10-15 parts of antibacterial filler, antibacterial components in the antibacterial plastic are of an organic-inorganic composite structure, the problem of precipitation cannot occur in the long-time use process, and the antibacterial plastic is high in antibacterial performance and good in antibacterial performance. Meanwhile, the antibacterial filler contains a quaternary ammonium salt and quaternary phosphonium salt composite structure, due to the composite structure, the antibacterial filler has positive charges and can be adsorbed on the surfaces of bacterial cells with negative charges through electrostatic adsorption, and a guanidine structure can further adsorb bacteria, so that the normal physiological functions of the bacteria are interfered, the permeability of cell membranes is changed, and the antibacterial effect is improved. And the zinc organic framework can release zinc cations, so that the metal cations are adsorbed on the cell membranes, and the leakage of nutrient substances in bacteria is accelerated.

The invention relates to the technical field of cationic etherifying agents, and discloses a quaternary ammonium salt type cationic etherifying agent and a preparation method thereof. The invention provides a quaternary ammonium salt type cationic etherifying agent by adding 3-chloro-2-hydroxypropyltrimethylammonium chloride and sulfaguanidine modified quaternized chitosan into a reactor, stirring, and obtaining the quaternary ammonium salt type cationic etherifying agent. The quaternary ammonium salt, guanidine group, and chitosan group contained in the sulfaguanidine modified quaternized chitosan all have good antibacterial effects; wherein the quaternary ammonium salt is adsorbed onto the bacterial cell surface, and the hydrophobic group is inserted into the lipid layer, thereby changing the permeability of the cell membrane, destroying the membrane structure, causing the leakage of intracellular substances, and causing bacterial death; the guanidine group can interfere with the normal metabolic process of the bacteria by combining with proteins and nucleic acids in the bacterial cells, further inhibiting the growth and reproduction of the bacteria, thereby playing a natural antibacterial effect; and the chitosan group itself has a good antibacterial effect.

The invention discloses a calcium-containing spray for preventing grape fruit cracking and a preparation method thereof, and belongs to the field of grape fruit cracking prevention, and the calcium-containing spray comprises the following components in parts by mass: 3-9 parts of bioactive peptide-polysaccharide chelated calcium, 5-8 parts of a cationic surfactant, 1-5 parts of a water-retaining agent, 0.3-0.85 part of sodium salt, 0.01-0.5 part of a growth promoter, 0.05-1 part of potassium fulvate and 50-800 parts of deionized water. The preparation method comprises the following steps: dissolving the bioactive peptide-polysaccharide chelated calcium, the sodium salt, the growth promoter and the potassium fulvate in deionized water, and then adding the water-retaining agent and the cationic surfactant to obtain a mixed solution; stirring the mixed solution at 60-85 DEG C, and then standing to obtain the calcium-containing spray for preventing grape fruit cracking, after spraying, a layer of uniform protective film can be formed, moisture permeation and external mechanical damage can be effectively reduced, osmotic pressure balance inside and outside cells can be effectively regulated, the stability of a cell structure can be maintained, and the grape cracking rate can be remarkably reduced.

The invention belongs to the technical field of high polymer materials, and discloses an antibacterial high-flame-retardant ABS composite material and a preparation method thereof, the antibacterial high-flame-retardant ABS composite material is processed from the following raw materials by weight: 100 parts of ABS resin, 15-25 parts of a composite flame retardant, 1-2 parts of a deodorant, 2-5 parts of a compatilizer, and 2.5-12 parts of a composite antibacterial agent. The ABS material has certain flame retardance, and ammonium polyphosphate, melamine polyphosphate, nano silicon dioxide and expanded graphite are mixed and added, so that the flame-retardant material can be decomposed at high temperature to generate a large amount of gas and water vapor, a protective layer is formed, flame spreading is prevented, the flame retardance of the material is greatly improved, and the flame-retardant performance of the material is improved. And by adding the compatilizer and the deodorant, the compatibility among the materials is high, no peculiar smell exists during production, the comfort degree during use is improved, the material is safe and environment-friendly, the product performance is improved, it is ensured that the material can be used in different fields, and the universality and practicability are improved.

The invention belongs to the field of botanical fungicide preparation, and particularly relates to a winter Chinese cabbage fungicide and a preparation method thereof. A potassium hydroxide solution is fully adsorbed by a prepared porous matrix through an esterification cross-linking reaction, an obtained efficient sterilization nanoparticle mixed viscous solution is extracted and concentrated to prepare a sterilization antiviral natural extract, and the prepared efficient sterilization suspension can effectively prevent and treat winter cabbage diseases; after polydimethylsiloxane and propylene glycol are mixed and emulsified, the disease-preventing and resistance-improving powder obtained through freeze drying is mixed in a formed breathable emulsion, and the prepared disease-preventing and resistance-improving composition can enable the Chinese cabbages in winter to maintain disease resistance for a long time; the mixture for promoting plant growth is uniformly mixed with the efficient sterilization component, and the prepared winter Chinese cabbage bactericide can efficiently prevent and treat diseases caused by pathogenic microorganisms, improves the disease resistance of plants, has biocompatibility and does not damage ecological balance.

The invention relates to the technical field of composite material preparation, and specifically discloses a composite preparation process for enhancing the mechanical properties of marine laminated wood. Wood powder, epoxy resin, antibacterial modified basalt fiber-titanium dioxide, a stabilizer and a curing agent are uniformly mixed, kneaded in an open mill, and hot-pressed in a hot press to obtain the marine laminated wood. The antibacterial modified basalt fiber-titanium dioxide contains a large number of active groups, which can form a three-dimensional staggered support network in a matrix, generate a cross-linked network structure, and effectively improve the mechanical properties of the matrix. The epoxy resin is used as an adhesive with strong bonding force, and can tightly bond the wood powder and other materials together, thereby reducing the waste of wood and improving the utilization rate of wood to achieve environmental benefits, forming a laminated wood with stable structure and high strength. Through a curing cross-linking reaction, a mesh structure can be formed, which further enhances the overall mechanical strength of the laminated wood and prolongs its service life.

This invention discloses a method for enhancing the antibacterial activity of Propionibacterium freudenreichii subsp. shermanii metabolites by adding a surfactant to a culture medium. The method uses Propionibacterium freudenreichii subsp. shermanii NBRC No. 12426 as the experimental strain and Pichia anomala SICC 2.894 as the indicator strain. A surfactant is added to the fermentation medium to enhance the antibacterial activity of the metabolites of Propionibacterium freudenreichii subsp. shermanii against the indicator strain Pichia anomala. Based on the culture conditions and method of Propionibacterium freudenreichii subsp. shermanii in this invention, the optimal concentration of the surfactant Tween-80 is selected as 0.3%, which significantly enhances the antibacterial activity of the metabolites of Propionibacterium freudenreichii subsp. shermanii.

The invention belongs to the technical field of antibacterial materials, and particularly relates to a composite nano material as well as a preparation method and application thereof. The composite nano material comprises modified mesoporous polydopamine coated with a hyaluronic acid membrane and gold modified on the surface of the hyaluronic acid membrane, the modified mesoporous polydopamine is prepared from copper ion chelated mesoporous polydopamine and BNN6 loaded on the copper ion chelated mesoporous polydopamine. Gold and mesoporous polydopamine in the composite nano material can absorb near-infrared light and convert the near-infrared light into heat under the irradiation of the near-infrared light, BNN6 is activated and can release NO gas harmful to fungi or bacteria along with temperature rise, and the NO gas can interfere the metabolic process of microorganisms, change the permeability of cell membranes, damage the cell membranes and inhibit the growth of the fungi or the bacteria, so that the growth of the fungi or the bacteria is inhibited. And even death is caused. According to the invention, NO gas and an inorganic antibacterial agent are jointly applied to microorganism resistance, and the antibacterial effect is good.

The invention belongs to the technical field of fabrics, and discloses an antibacterial breathable fabric and a preparation process thereof; 3-chloro-2-hydroxypropionic acid; a blocked polyether polyurethane and 5-nitroisophenylene (N-dimethylaminoethylformamide) undergo quaternization polymerization reaction, and finally the nitro group is reduced by sodium dithionite to obtain a novel amino quaternary ammonium salt polyurethane finishing agent. The amino quaternary ammonium salt polyurethane finishing agent contains a large number of amino groups, which can react with the aldehyde group of the oxidized cotton fabric to produce a Schiff base reaction, so that the quaternary ammonium salt polyurethane finishing agent is chemically grafted to the surface of the cotton fabric, so that the cotton fabric maintains excellent hydrophilic moisture permeability; the amino quaternary ammonium salt polyurethane finishing agent contains a large number of quaternary ammonium salt antibacterial groups in the main chain, and the cotton fabric exhibits strong bactericidal performance after finishing. After washing, the quaternary ammonium salt polyurethane finishing layer is not easy to fall off, and still maintains excellent bactericidal effect.

The invention provides a manufacturing method of a semiconductor device, which comprises the following steps of: providing a semiconductor substrate comprising a first pattern region and a second pattern region, and performing floating gate polycrystalline silicon deposition on the semiconductor substrate to form a first polycrystalline silicon layer; the pattern density of the first pattern area is greater than that of the second pattern area; performing ion implantation on the first polycrystalline silicon layer, and forming an oxide layer on the top surface of the first polycrystalline silicon layer; protecting the oxide layer of the second pattern area and etching the oxide layer of the first pattern area; performing chemical mechanical polishing treatment on the first polycrystalline silicon layer in the first pattern area and the oxide layer and the first polycrystalline silicon layer in the second pattern area; and generating the semiconductor device based on the first polycrystalline silicon layer after the chemical mechanical polishing treatment. The thickness of the polycrystalline silicon layer in the areas with different pattern densities can be ensured to be consistent, so that the reliability of the semiconductor device is improved, and the process is simple and convenient, high in flexibility and easy to implement.

The invention relates to the technical field of composite materials, and discloses industrial artificial granite and a preparation method thereof. Comprising the following components in parts by weight: 100 parts of granite particles, 25-40 parts of aluminum hydroxide filler, 10-15 parts of aluminum silicate microspheres, 50-60 parts of vinyl unsaturated polyester resin, 5-25 parts of alkenyl phosphorus-nitrogen quaternary ammonium salt modified sepiolite powder, 2-5 parts of a hardening agent, 1-3 parts of an initiator, 0.8-1.5 parts of an accelerant, 5-8 parts of color master batch and 20-30 parts of deionized water. Wherein quaternary ammonium salt in the alkenyl phosphorus-nitrogen quaternary ammonium salt modified sepiolite powder has excellent antibacterial and mildew-proof properties, the nitrogen-phosphorus-silicon synergistic sepiolite powder remarkably enhances the flame-retardant and heat-resistant properties of granite, forms a compact network structure with granite particles, filler and the like through chemical bonding, and has good mechanical properties; the artificial granite provided by the invention is simple in preparation process, safe and environment-friendly, and can meet harsh industrial application requirements.

The invention provides a sea cucumber peptide microsphere compound. The sea cucumber peptide microsphere compound is nanoparticles formed by wrapping sea cucumber peptide with chitosan analogues, and the chitosan analogue is any one of chitosan, carboxymethyl chitosan and hydroxypropyl chitosan. The HP-CS-NPS (or HPStide-N) provided by the invention provides an innovative active ingredient solution for developing efficient, stable and multifunctional gynecological nursing, cosmetics and skin care products, and is particularly suitable for nursing and repairing sensitive skin and acne skin.

The invention relates to the technical field of composite materials, and discloses an antistatic composite material based on ultra-high molecular weight polyethylene, the composite material is prepared from the following raw materials: ultra-high molecular weight polyethylene, polypropylene, coffee grounds, an antioxidant, a cross-linking agent, a lubricant, a foaming agent, graphene and a functional additive; the composite material is crosslinked with a matrix material to form a polymer network structure, a conductive network is further improved, gaps of graphene are filled with the polymer network to form a stable and compact conductive network, disconnection of a conductive path can be avoided, the antistatic performance of the composite material is further improved, and meanwhile the composite material is endowed with excellent and long-term antibacterial performance. The probability that antibacterial substances are separated out in the long-term use process is effectively reduced, the composite material is prevented from being eroded by bacteria, and the service life of the composite material is prolonged.

The invention relates to the technical field of materials, and discloses an enhanced nano composite catalyst based on MOFs material, a preparation method and an application thereof. The invention comprises the following steps: step 1: copper ions and zinc ions are coordinated with 2-methylimidazole as metal sources, and Cu / ZIF is obtained through centrifugation, washing and freeze drying; step 2: thiosulfate and calcium salt are subjected to replacement reaction to obtain CaS2O3; step 3: the Cu / ZIF solution obtained in step 1 and the CaS2O3 solution obtained in step 2 are fully mixed, polyethylene glycol PEG is added and fully mixed for reaction, so as to obtain the desired nano composite catalyst; the invention adopts PEG to wrap Cu / ZIF and load CaS2O3 to obtain Cu / ZIF / Ca / P, and bimetallic zinc and copper are used to co-construct an organic metal framework and load CaS2O3 for enhancing chemodynamic therapy and calcium death synergistic treatment.

The invention relates to a sustainable waterproof mildew-proof soybean protein adhesive and a preparation method thereof, and belongs to the technical field of soybean protein adhesives. The sustainable waterproof mildew-proof soybean protein adhesive is prepared from the following raw materials in parts by mass: 15 to 35 parts of soybean meal, 55 to 75 parts of water, 2 to 6 parts of cross-linking agent, 0.1 to 0.5 part of sodium carboxymethyl cellulose and 0.5 to 2 parts of ethyl lauroyl arginate hydrochloride. According to the invention, sodium carboxymethyl cellulose, ethyl lauroyl arginate hydrochloride and a cross-linking agent are introduced into a soybean meal system, so that the sustainable water-resistant mildew-proof soybean protein adhesive is prepared. The lauroyl arginine ethyl ester hydrochloride, the soybean meal and the sodium carboxymethyl cellulose respectively form high-specificity guanidyl carboxylate bridge hydrogen bonds, so that a heterogeneous structure is formed in a system, internal energy dissipation is improved, and the toughness and the water resistance of the adhesive are further improved. Meanwhile, due to the broad-spectrum antibacterial property of the ethyl lauroyl arginate hydrochloride, the adhesive has better corrosion-resistant and antibacterial effects.

The utility model discloses a device for improving the permeability of a ricefield eel culture net cage, and particularly relates to the technical field of culture net cages, the device comprises a first transverse plate and a first mesh frame, the first mesh frame is fixedly sleeved on the outer side of the first transverse plate, and a second mesh frame is movably arranged on the outer side of the first mesh frame. And a second transverse plate is fixedly connected to the edge of the bottom in the second mesh frame, a bottom plate is arranged at the bottom of the second transverse plate, a connecting assembly is arranged between the bottom plate and the second transverse plate, and the connecting assembly comprises two first connecting plates, two second connecting plates and locking bolts. The locking bolt is rotated to be far away from the first connecting plate and the second connecting plate, the second mesh frame is moved downwards, the meshes in the second mesh frame and the meshes in the first mesh frame are staggered, in the same way, the meshes in the second mesh frame and the meshes in the first mesh frame coincide, operation is easy, and operation is convenient. The permeability of the culture net cage can be conveniently changed, and the use effect is good.

The invention relates to the technical field of medicine synthesis, in particular to copper-cefazolin nanoparticles and a preparation method and application thereof. The copper-cefazolin nanoparticle provided by the invention comprises copper ions and cefazolin coordinated with the copper ions. The copper-cefazolin nano-particles provided by the invention have a relatively strong killing effect on bacteria (staphylococcus aureus), ROS can be generated under an acidic condition to change the permeability of bacterial cell membranes, and meanwhile, the copper-cefazolin nano-particles flow into the bacteria and down-regulate copper ion transporters, so that the copper-cefazolin nano-particles have a long-acting, stable and remarkable antibacterial effect. In addition, the copper-cefazolin nanoparticles can down-regulate inflammatory cytokines, activate peripheral nerves and promote vascular remodeling and hair follicle regeneration under a weakly alkaline condition, and have a good treatment effect on infectious wounds.

The invention relates to the technical field of etherifying agents, and discloses a cationic etherifying agent and a preparation method thereof. The invention obtains a cationic etherifying agent by adding guanidine quaternary ammonium salt, quaternary phosphonium salt polyacrylamide and glycidyl triethylammonium chloride into a reactor and stirring. The polyhexamethylene biguanide in the guanidine quaternary ammonium salt electrostatically adsorbs with the anion site on the surface of bacterial cells, denatures or destroys the cell structure, and plays a bactericidal role; the quaternary ammonium salt is adsorbed onto the surface of the bacteria, and the hydrophobic group is inserted into the lipid layer, so that the intracellular substances leak out, resulting in bacterial death; the guanidine group and the quaternary ammonium salt play a synergistic effect, and play a stronger bactericidal role; in the quaternary phosphonium salt polyacrylamide, the quaternary phosphonium salt carries a positive charge, can be adsorbed onto the bacterial cell wall and penetrate the cell membrane, reacts with the lipid or protein of the cell membrane, lyses the cell wall, and causes bacterial death; the quaternary phosphonium salt is grafted into chitosan and polyacrylamide, and the positive charge density is increased, thereby enhancing the antibacterial effect.

The invention discloses a preparation method and application of an antibacterial water inlet screen, which comprises the following raw materials by weight: 0.1-5 parts of a reinforcing agent, 0.1-5 parts of an antibacterial agent, 0.2-0.4 parts of an antioxidant and 100-120 parts of a base resin. The reinforcing agent is composed of an organic and an inorganic part. The organic part, quaternary phosphonium salt and quaternary ammonium salt, both have the ability to adsorb negatively charged bacteria. At the same time, the long-chain hydrophobic group of the quaternary ammonium salt can also be inserted into the lipid layer of the bacteria, changing the permeability of the cell membrane, destroying the membrane structure and inhibiting cell activity. The inorganic part, titanium dioxide, can destroy the cell membrane and cell wall of bacteria and kill bacteria. The mesoporous silica and titanium dioxide composite simultaneously carry a large number of thorny AuNR particles, which puncture the cell membrane of bacteria while adsorbing bacteria, greatly improving the efficiency of sterilization.

This invention relates to the field of microbial fermentation technology, and particularly to *Phellinus linteus* mycelium, a method for increasing the polysaccharide yield of *Phellinus linteus* mycelium, and their applications. The method involves placing *Phellinus linteus* mycelium in an alternating magnetic field environment with a magnetic field strength of 2 mT to 20 mT and a frequency of 2 Hz to 100 Hz during the late logarithmic growth phase to the early stationary phase of its cultivation. Compared to a control group without magnetic field treatment, this method can increase the intracellular polysaccharide yield of *Phellinus linteus* mycelium by 10%–95%, while maintaining stable or slightly increased mycelial biomass. Furthermore, this method is a purely physical stimulation, introducing no chemical substances into the fermentation system, resulting in no pollution or residue, and aligns with the development direction of green biomanufacturing.