5results about How to "Change permeability" patented technology

This invention discloses a method for enhancing the antibacterial activity of Propionibacterium freudenreichii subsp. shermanii metabolites by adding a surfactant to a culture medium. The method uses Propionibacterium freudenreichii subsp. shermanii NBRC No. 12426 as the experimental strain and Pichia anomala SICC 2.894 as the indicator strain. A surfactant is added to the fermentation medium to enhance the antibacterial activity of the metabolites of Propionibacterium freudenreichii subsp. shermanii against the indicator strain Pichia anomala. Based on the culture conditions and method of Propionibacterium freudenreichii subsp. shermanii in this invention, the optimal concentration of the surfactant Tween-80 is selected as 0.3%, which significantly enhances the antibacterial activity of the metabolites of Propionibacterium freudenreichii subsp. shermanii.

The invention provides a manufacturing method of a semiconductor device, which comprises the following steps of: providing a semiconductor substrate comprising a first pattern region and a second pattern region, and performing floating gate polycrystalline silicon deposition on the semiconductor substrate to form a first polycrystalline silicon layer; the pattern density of the first pattern area is greater than that of the second pattern area; performing ion implantation on the first polycrystalline silicon layer, and forming an oxide layer on the top surface of the first polycrystalline silicon layer; protecting the oxide layer of the second pattern area and etching the oxide layer of the first pattern area; performing chemical mechanical polishing treatment on the first polycrystalline silicon layer in the first pattern area and the oxide layer and the first polycrystalline silicon layer in the second pattern area; and generating the semiconductor device based on the first polycrystalline silicon layer after the chemical mechanical polishing treatment. The thickness of the polycrystalline silicon layer in the areas with different pattern densities can be ensured to be consistent, so that the reliability of the semiconductor device is improved, and the process is simple and convenient, high in flexibility and easy to implement.

The invention provides a sea cucumber peptide microsphere compound. The sea cucumber peptide microsphere compound is nanoparticles formed by wrapping sea cucumber peptide with chitosan analogues, and the chitosan analogue is any one of chitosan, carboxymethyl chitosan and hydroxypropyl chitosan. The HP-CS-NPS (or HPStide-N) provided by the invention provides an innovative active ingredient solution for developing efficient, stable and multifunctional gynecological nursing, cosmetics and skin care products, and is particularly suitable for nursing and repairing sensitive skin and acne skin.

The utility model discloses a device for improving the permeability of a ricefield eel culture net cage, and particularly relates to the technical field of culture net cages, the device comprises a first transverse plate and a first mesh frame, the first mesh frame is fixedly sleeved on the outer side of the first transverse plate, and a second mesh frame is movably arranged on the outer side of the first mesh frame. And a second transverse plate is fixedly connected to the edge of the bottom in the second mesh frame, a bottom plate is arranged at the bottom of the second transverse plate, a connecting assembly is arranged between the bottom plate and the second transverse plate, and the connecting assembly comprises two first connecting plates, two second connecting plates and locking bolts. The locking bolt is rotated to be far away from the first connecting plate and the second connecting plate, the second mesh frame is moved downwards, the meshes in the second mesh frame and the meshes in the first mesh frame are staggered, in the same way, the meshes in the second mesh frame and the meshes in the first mesh frame coincide, operation is easy, and operation is convenient. The permeability of the culture net cage can be conveniently changed, and the use effect is good.

This invention relates to the field of microbial fermentation technology, and particularly to *Phellinus linteus* mycelium, a method for increasing the polysaccharide yield of *Phellinus linteus* mycelium, and their applications. The method involves placing *Phellinus linteus* mycelium in an alternating magnetic field environment with a magnetic field strength of 2 mT to 20 mT and a frequency of 2 Hz to 100 Hz during the late logarithmic growth phase to the early stationary phase of its cultivation. Compared to a control group without magnetic field treatment, this method can increase the intracellular polysaccharide yield of *Phellinus linteus* mycelium by 10%–95%, while maintaining stable or slightly increased mycelial biomass. Furthermore, this method is a purely physical stimulation, introducing no chemical substances into the fermentation system, resulting in no pollution or residue, and aligns with the development direction of green biomanufacturing.