24 results about "Phellinus linteus" patented technology

The invention provides application of a phellinus polyketide synthase gene SvPKS1 in promoting bioluminescence of fungi or plants, the coding sequence of the SvPKS1 is shown as SEQ ID NO.1, and the fungi are fungi for producing caffeic acid. According to the application, the SvPKS1 and other genes (nnH3H, nnLuz and nnCPH) of an FBP fungus luminescence pathway are co-expressed in fungi or plants by utilizing a transgenic technology, so that the fungi or plants are promoted to emit light biologically. The invention discloses co-expression of the phellinus polyketide synthase gene SvPKS1 and fungus luminescence pathway genes nnH3H, nnLuz and nnCPH for the first time, promotes fungus or plant bioluminescence, and provides a key candidate enzyme gene for promoting fungus or plant sustainable luminescence.

The invention discloses a method for enhancing the flavor of sea buckthorn fruit vinegar through synergistic fermentation of multiple strains combined with medicinal and edible raw materials. Wickerhamomyces anomalus YCJP320 with clear hereditary characteristics and proprietary intellectual property rights (CGMCC No. 33925, which can produce esterifying enzyme at high yield and increase aroma components such as ester components) and acetobacter pasteurianus CL247, CGMCC No. 33924, which can resist 18% ethanol and 7% acetic acid, and can produce acid efficiency are respectively used for alcoholic fermentation and acetic fermentation, and then fermentation is carried out, so that the fermentation efficiency is improved. According to the fermentation production process of the sea buckthorn fruit vinegar, ganoderma lucidum post-prebiotics, phellinus linteus post-prebiotics and medicinal and edible raw materials (astragalus membranaceus, dogwood and cinnamon) are used as fermentation culture medium components for nutrient enrichment, so that directional regulation and control of flavor substances and functional components of the sea buckthorn fruit vinegar are realized.

The invention relates to the technical field of health-care beverages, and particularly provides effervescent tablets for regulating blood sugar as well as a preparation method and application of the effervescent tablets. The effervescent tablet comprises the following raw materials in parts by weight: 20-30 parts of grifola frondosa polysaccharide, 10-25 parts of ganoderma lucidum polysaccharide, 5-15 parts of phellinus igniarius polysaccharide, 8-12 parts of citric acid, 15-30 parts of sodium bicarbonate, 10-15 parts of a filling agent, 3-5 parts of an adhesive, 0.5-2 parts of a sweetening agent and 1-3 parts of a lubricating agent, adopts a direct tabletting technology, and comprises the steps of material mixing, drying, uniform mixing and tabletting. The process is simplified, manpower, time, water and electricity are saved, the production cost is greatly reduced, and the blood sugar reducing effect is obvious through the steps of adjusting the reasonable amount of the acid agent and the reasonable amount of the alkali agent and finishing the granules.

The invention belongs to the technical field of biocontrol bacteria. The invention relates to trichoderma aureobasidium, in particular to trichoderma aureobasidium antagonistic to wood-rotting fungi and epidemic blight and application of the trichoderma aureobasidium. The invention provides a Trichoderma aureobasidium P21-3 separated from soil, which is preserved in Guangdong Microbial Culture Collection Center on September 5, 2025, and the preservation number of the Trichoderma aureobasidium P21-3 is GDMCC No: 66930. The compound has a remarkable inhibiting effect on various wood-rot pathogenic bacteria and epidemic disease pathogenic bacteria of elaeagnus coriolis, including ganoderma sinense, phellinus xylaris harmful, cryptophyllothecium elaticum and the like, and the antibacterial rate reaches 80% or above; the method has a strong prevention and control capability on the durian epidemic disease which outbreaks in recent years and does not have an efficient prevention and control means. As a natural biocontrol fungus, the P21-3 strain and its fermentation broth / metabolite have the advantages of environmental friendliness, ecological safety, no chemical residue and the like, can effectively replace or significantly reduce the use of traditional chemical bactericides, is an excellent biocontrol fungus resource, has significant ecological benefits, social benefits and economic benefits, and has wide industrial application prospects.

The invention relates to the technical field of functional food processing, in particular to fermented tea with an alcoholic liver injury protection function and a preparation method of the fermented tea. The functional tea beverage is prepared by optimizing the fungus compatibility proportion, the fermentation condition and the subsequent blending process, and the method is provided for dietary intervention of alcoholic liver injury due to the regulation effect on hepatic cell oxidative stress and inflammatory factors. The preparation method comprises the following steps: mixing the lucid ganoderma, the phellinus igniarius, the grifola frondosa and pure water according to a weight ratio of 1: 30, carrying out water bath extraction at 90 DEG C for 2-4 hours, filtering, mixing extract liquids according to a ratio, and adjusting the pH value to 5.0-6.0; inoculating yeast into a YPD culture medium, culturing at 22-31 DEG C for 24-96 hours until the pH value is 5.0-6.5 to obtain a yeast liquid, inoculating the obtained yeast liquid into the extract liquid obtained in the step 1), fermenting at 28 DEG C for 72 hours, and adjusting the pH value to 5.5; and heating at 60-70 DEG C for 10-15 minutes to inactivate the yeast, filtering, and refrigerating and storing.

The invention belongs to the technical field of health care, and particularly relates to essential oil for releasing fascia through a stone needle and a preparation method and application of the essential oil. According to the essential oil, sunflower seed oil and peony seed oil serve as base oil, turmeric root oil, ginger root oil and wintergreen leaf oil are matched, active ingredients such as phellinus igniarius polysaccharide extract, polyphyllin extract, borneol and tocopherol are added, the formula is scientific, and the synergistic effect is obvious. The preparation method relates to the processes of multi-enzyme synergistic enzymolysis, supercritical CO2 extraction, molecular distillation, efficient extraction, purification and the like, and high-activity and high-purity key components can be obtained. The essential oil disclosed by the invention has good permeability, anti-inflammatory property, repairability and safety, can remarkably improve the smoothness and comfort of fascia release of the stone needle knife, and is suitable for multiple physiotherapy scenes such as fascia rehabilitation, soft tissue repair and pain relief.

The invention provides a phellinus igniarius polyphenol extract as well as a preparation method and application thereof, and belongs to the technical field of phellinus igniarius extraction. The preparation method of the phellinus igniarius polyphenol extract comprises the following steps: mixing phellinus igniarius powder with an ethanol solution, carrying out ultrasonic treatment, standing overnight, and centrifuging to take supernatant, so as to obtain a phellinus igniarius alcohol extract; drying the phellinus igniarius alcohol extract to obtain a phellinus igniarius polyphenol extract; the volume fraction of ethanol in the ethanol solution is 55%-65%; the mass volume ratio of the phellinus igniarius powder to the ethanol solution is 1g: (45-55) mL; the phellinus igniarius polyphenol extract mainly contains active ingredients such as osmundone, and lipid metabolism disorder, oxidative stress and neurotoxicity caused by microplastics can be improved. The phellinus igniarius polyphenol extract is used for the research of relieving the toxicity of the microplastics, and a theoretical basis is provided for the application of the phellinus igniarius polyphenol extract in drug development.

The invention relates to the technical field of medicines, in particular to application of a pharmaceutical composition in preparation of a medicine for treating thalassemia. The invention provides a pharmaceutical composition. The pharmaceutical composition is prepared from the following components in parts by mass: 2 to 5 parts of pravastatin sodium, 1 to 2 parts of roteciterp, 7 to 11 parts of deferasirox, 7 to 11 parts of morroniside and 30 to 40 parts of phellinus igniarius general flavone extract. The pharmaceutical composition provided by the invention shows multiple clinical beneficial effects in treatment of thalassemia. In the aspect of curative effect, the composition can significantly increase the number of peripheral red blood cells, the content of hemoglobin and the hematocrit of the peripheral blood of a patient and effectively reduce the variable coefficient of the volume of the red blood cells, which indicates that the composition not only can improve the anemia state, but also can improve the stability of the quality of the red blood cells. Besides, the traditional Chinese medicine composition can obviously relieve spleen enlargement and iron overload degree and reduce the iron deposition level of the liver and the spleen, so that the traditional Chinese medicine composition has a positive effect in the aspects of relieving hemolysis related complications and organ iron toxicity.

The invention discloses a morin derivative and a preparation method and application thereof, the morin derivative has the following molecular structure expression, the derivative not only has significantly improved hypoglycemic effect, but also is beneficial to improvement of biosafety compared with existing sulfonylurea drugs; .

The invention provides a plant extraction compound factor with anti-inflammatory and anti-allergy functions and a preparation method thereof, and relates to the technical field of skin care product processing, the plant extraction compound factor is prepared from the following raw materials by weight: 8-10 parts of gentiana macrophylla, 5-7 parts of swertia mileensis, 4-6 parts of stephania tetrandra, 6-8 parts of phellinus igniarius, and 7-9 parts of peony. The plant extraction compound factor is prepared from the following raw materials in parts by weight: 5-7 parts of eucommia ulmoides, 4-6 parts of magnolia sieboldii, 6-8 parts of andrographis paniculata and 3-5 parts of polygala tenuifolia, and the plant extraction compound factor is prepared from the following raw materials in parts by weight: 8-10 parts of centella asiatica, 3-5 parts of bamboo shavings, 5-7 parts of fructus forsythiae and 4-6 parts of amur corktree. The plant extraction compound factor is prepared from the following raw materials in parts by weight: 3-5 parts of coreopsis tinctoria, 7-9 parts of liquorice, 2-4 parts of pelargonium graveolens and 3-5 parts of broom leaf Australian tea.

The present invention relates to a composition for improving, treating or preventing hearing disorders, the composition comprising, as an active ingredient, one or more substances selected from the group consisting of a semen cassiae (L.) Roxb. Extract, a buckwheat (L.) MOENCH. Extract, a sorghum (L.) extract, and a Phellinus linteus (L.) extract, and, more specifically, to a composition for improving, treating or preventing hearing disorders, the composition comprising, as an active ingredient, one or more substances selected from the group consisting of a semen cassiae (L.) Roxb. Extract, a buckwheat (L.) MOENCH. Extract, a sorghum (L.) Morr. Extract, and a Phellinus linteus (L.) Morr. The semen cassiae extract, the buckwheat extract, the sorghum extract or / and the phellinus igniarius extract have the auditory function recovery function; as a result, the compound can be effectively used as a pharmaceutical composition, a food composition, a functional health food, a quasi-pharmaceutical composition, and a feed composition.

This invention discloses a nasal administration of traditional Chinese medicine composition for adjuvant cancer treatment and its preparation method, comprising the following raw materials in parts by weight: each part is 1 gram, including 5-10 parts of Phellinus linteus, 4-9 parts of Ganoderma lucidum, 5-10 parts of Panax notoginseng, 3-8 parts of Cremastra appendiculata, 4-9 parts of Ligustrum lucidum, 1-5 parts of Cordyceps sinensis, 8-14 parts of Prunus persica, 2-5 parts of scallion, 3-15 parts of bitter almond, 8-15 parts of jujube, 3-6 parts of pepper, 50-60 parts of gypsum, 2-8 parts of Croton tiglium, 0.2-0.5 parts of arsenic trioxide, 1-5 parts of calomel, and 2-4 parts of ginger. This invention utilizes nasal inhalation via the mucous membrane for administration, achieving effects such as inhibiting tumor cells, enhancing the body's immune function, shortening the treatment cycle, and reducing side effects, making it suitable for adjuvant treatment of various cancers.

The invention relates to the technical field of biological medicine, and particularly discloses application of phellinus linteus in preparation of a TRIM24 protein inhibitor. The research finds that the phellinus linteus can be directly combined with the TRIM24 protein, so that the phellinus linteus can be used as a TRIM24 protein inhibitor and can be used for solving the problem of promoting tumor proliferation caused by the activation of the TRIM24 protein. Besides, the invention also discovers that the proliferation capacity of tumor cells is weakened along with the increase of the concentration of the phellinus linteus, and an effective way is provided for the subsequent research on the aspect of TRIM24 protein inhibitors or antitumor drugs. In addition, the phellinus linteus ketone is high in safety, low in price and good in development and utilization prospect.

This invention discloses a traditional Chinese medicine composition containing Cordyceps militaris and its application in the treatment of tumors, relating to the field of traditional Chinese medicine technology. The composition comprises active ingredients and excipients. The active ingredients, by weight, include the following components: fermented mycelium powder, total flavonoid extract from Actinidia chinensis root, total saponin extract from Astragalus membranaceus, polysaccharide extract from Phellinus linteus, and tannin extract from Phyllanthus emblica. This method uses highly active Cordyceps militaris strains as the core raw material, combined with a multi-component synergistic formulation system, to systematically target and regulate the drug-forming defects along the entire metabolic chain in vivo. It achieves a synergistic effect throughout the entire process, from extracellular degradation protection and cell membrane entry promotion to intracellular activation enhancement and long-term maintenance of activity. This solves the core problems of low bioavailability and insufficient effective concentration at tumor sites, reducing the limitations of existing compositions that only achieve simple additive drug effects, and significantly improving the antitumor activity and stability of the composition.

The present invention provides a method of manufacturing health functional food containing aloeswood, including: a material preparation step in which materials are prepared by washing each of aloeswood, mulberry Phellinus linteus, Houttuynia cordata Thunb., Saururus chinensis, green tea or puer tea, Stachys sieboldii, Lycopus lucidus Turcz., Agrimonia pilosa, and Panax notoginsengs, and then drying in the shade; a material pulverization step in which each of those, dried through the material preparation step, is pulverized; and a molding step in which, after the material pulverization step is completed, powders thereof are mixed to prepare a material mixture, honey is mixed, and the resulting mixture is molded into a desired shape.

This invention relates to a method for cultivating Phellinus linteus, and pertains to the field of Phellinus linteus cultivation technology. The method includes substrate preparation, inoculation and mycelial cultivation, cultivation management, and collection steps. This invention employs an organic cultivation method where yellowing occurs directly at the inoculation site. Utilizing the natural high-oxygen channel at the inoculation site, mycelia are directed and enriched along the path of least resistance, promoting rapid differentiation of Phellinus linteus primordia at the site and direct entry into normal growth. This results in uniform and timely yellowing, further improving the yield and quality of Phellinus linteus. Simultaneously, the overall cultivation cycle is controllable, making it suitable for large-scale, efficient production of organic Phellinus linteus.

The present invention provides a method of preparing aloeswood water, including: a material preparation step in which materials are prepared by washing each of aloeswood, Phellinus linteus, Houttuynia cordata Thunb., Saururus chinensis, green tea or puer tea, Stachys sieboldii, Lycopus lucidus Turcz., Agrimonia pilosa, and Panax notoginsengs, and then drying in the shade; a material pulverization step in which each of those, dried through the material preparation step, is pulverized; a boiling step in which, after the material pulverization step is completed, the powders thereof are mixed to prepare a material mixture, water is mixed, and the resulting mixture is heated and boiled; an infusing step in which, after the boiling step is completed, infusing is performed by cooling the boiled water; and a reduced pressure distillation step in which, after the infusing step is completed, the infused water is distilled under reduced pressure.

The preparation method comprises the following steps: grinding green tea, sieving, adding deionized water according to a mass-volume ratio of 1: 20 g / ml, sterilizing, cooling to room temperature, inoculating a phellinus linteus strain, fermenting at 28 DEG C at 180 r / min for 12 days to obtain fermentation liquor, centrifuging, collecting supernate, and performing vacuum freeze drying to obtain the poplar and phellinus linteus fermented tea. The diet-induced obesity is improved by cooperatively regulating and controlling liver lipid metabolism and intestinal flora, the effect is better than that of unfermented tea, and a new research thought is provided for improving the obesity by taking the fermented tea as a diet intervention means.

The utility model relates to the technical field of extraction devices, and discloses a phellinus igniarius combined polysaccharide extraction device which comprises a box body, the top end of the box body is fixedly sleeved with a feeding pipe, and the bottom end of the feeding pipe is fixedly sleeved with a primary crushing cylinder; through the flow design of multi-stage crushing, vibration screening and circulating treatment, the phellinus igniarius is crushed twice by the first crushing cutter and the second crushing cutter, coarse crushing is converted into fine crushing, the particle size of materials can be fully reduced, high-quality raw materials are provided for subsequent polysaccharide extraction, the extraction efficiency is remarkably improved, and the production cost is reduced. Then, a double-groove belt wheel drives a cam on a transmission shaft through a second belt, a screening plate vibrates, screening holes are effectively prevented from being blocked, it is ensured that the screening process is smooth, the screening efficiency is improved, it is ensured that the particle size of discharged materials is uniform, and finally unqualified large-particle materials are conveyed back to the primary crushing barrel through an auger and a conveying pipe in the feeding box to be circularly treated. The particle size of the finally discharged material reaches the standard, the raw material quality is guaranteed, and the polysaccharide extraction effect is stabilized.

This invention provides a *Phellinus linteus* polyketide synthase gene. SvPKS1 Applications in promoting bioluminescence in fungi or plants, the SvPKS1 The coding sequence is shown in SEQ ID NO.1, and the fungus is a caffeic acid-producing fungus. The application includes using transgenic technology to... SvPKS1 Other genes in the FBP fungal luminescence pathway ( nnH3H , nnLuz , nnCPH This invention discloses for the first time the *Phellinus linteus* polyketide synthase gene, which is co-expressed in fungi or plants to promote bioluminescence in fungi or plants. SvPKS1 With fungal luminescence pathway genes nnH3H , nnLuz , nnCPH Co-expression promotes bioluminescence in fungi or plants, providing a key candidate enzyme gene for promoting sustainable bioluminescence in fungi or plants.

The invention discloses a Sparassis crispa-containing skin care composition as well as a preparation method and application thereof. The Sparassis crispa-containing skin care composition comprises a Sparassis crispa fermentation product and at least one active component of phellinus linteus, maitake, armillaria mellea, tremella aurantialba and lucid ganoderma. The moisturizing performance of the skin care composition is obviously superior to that of a single strain component or a simple mixture, the skin care composition can effectively improve the problems of skin dryness, tightness and fine wrinkles, and the skin care composition is safe and free of irritation. The skin care composition can be used for preparing skin care products.

This invention discloses a uric acid-lowering probiotic-Sanghuang compound and its preparation method, specifically involving the use of Mythical Pig Host-Associated Lactobacillus (Sanghuang Compound). Ligilactobacillus saerimneri The compound preparation was obtained by combining *Lactobacillus 6-2* with extracts of *Phellinus linteus*. *Lactobacillus 6-2*, associated with the Mythical Pig Host, was deposited on December 1, 2025, at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 36865. The extract of *Phellinus linteus* was obtained through alcohol extraction, water extraction, filtration, centrifugation, and vacuum concentration. The combination of these two preparations exhibits a good uric acid-lowering effect and can simultaneously improve liver and kidney damage induced by hyperuricemia. Combined use can also improve hyperuricemia by regulating the intestinal flora structure. Therefore, the compound preparation prepared in this invention can be used to prepare drugs for the prevention or treatment of uric acid, opening up a new avenue for the comprehensive development and utilization of probiotics and *Phellinus linteus*.

This invention relates to the field of microbial fermentation technology, and particularly to a co-culture fermentation broth of medicinal and edible fungi with whitening effects, its preparation method, and its application. The preparation method of the co-culture fermentation broth of medicinal and edible fungi with whitening effects includes: inoculating the seed liquid of a first fungus and the seed liquid of a second fungus into a co-fermentation medium for fermentation and co-culture to obtain the co-culture fermentation broth of medicinal and edible fungi with whitening effects; the first fungus includes at least one of *Ganoderma lucidum* strain, *Trametes versicolor* strain, *Poria cocos* strain, *Auricularia auricula-judae* strain, *Phellinus linteus* strain, and *Aspergillus schavar*; the second fungus includes *Schizophyllum commune*. This invention co-cultures *Schizophyllum commune* with other specific strains and found that co-culturing the two strains can exert a synergistic effect, thereby significantly improving the tyrosinase inhibition effect of the fermentation broth. The optimal combination of fermentation broth can achieve a tyrosinase inhibition rate of over 90%, and even 1 wt% of the fermentation broth has a tyrosinase inhibition effect of approximately 90%.

This invention relates to the field of microbial fermentation technology, and particularly to *Phellinus linteus* mycelium, a method for increasing the polysaccharide yield of *Phellinus linteus* mycelium, and their applications. The method involves placing *Phellinus linteus* mycelium in an alternating magnetic field environment with a magnetic field strength of 2 mT to 20 mT and a frequency of 2 Hz to 100 Hz during the late logarithmic growth phase to the early stationary phase of its cultivation. Compared to a control group without magnetic field treatment, this method can increase the intracellular polysaccharide yield of *Phellinus linteus* mycelium by 10%–95%, while maintaining stable or slightly increased mycelial biomass. Furthermore, this method is a purely physical stimulation, introducing no chemical substances into the fermentation system, resulting in no pollution or residue, and aligns with the development direction of green biomanufacturing.