6 results about "Low density lipoprotein cholesterol" patented technology

This invention relates to a traditional Chinese medicine composition, specifically a traditional Chinese medicine composition for treating diabetic nephropathy, belonging to the fields of medicine and health products. The traditional Chinese medicine composition of this invention is made from components comprising the following raw materials: yam, salvia miltiorrhiza, rosehip, turtle shell, cornus officinalis, dioscorea hypoglauca, cuscuta chinensis, oyster shell, and American ginseng. Through rational formulation, this traditional Chinese medicine composition utilizes the principle of clearing heat and removing dampness, with the synergistic effect of multiple drugs, to significantly reduce fasting blood glucose, improve glucose metabolism, lower low-density lipoprotein cholesterol and triglycerides, and raise high-density lipoprotein cholesterol to regulate lipid metabolism, reduce weight, and has no significant damage to liver and kidney function, with minimal side effects.

This invention discloses an oil composition with a balanced fatty acid ratio and lipid-lowering effects, and its applications. The oil composition comprises vegetable oil, probiotics, phospholipids from camellia seed cake, gelatin, and sodium alginate. It effectively reduces serum triglyceride, total cholesterol, and low-density lipoprotein cholesterol levels while increasing high-density lipoprotein cholesterol levels, exhibiting a good lipid-lowering effect. Furthermore, when the oil composition is formulated into microcapsules, it exhibits good stability, encapsulation efficiency, and release rate. The oil composition also helps maintain the activity of probiotics, allowing for better preservation and efficacy. Based on this, this invention also provides a candy containing the oil composition, enriching the variety of products with lipid-lowering effects and promoting the development of lipid-lowering related products.

This invention discloses the application of verbascoside in the preparation of drugs for treating obesity and related metabolic disorders, relating to the field of biopharmaceuticals. The drug upregulates the expression of phosphorylated AMP-activated protein kinase α and carnitine palmitoyltransferase-1α, while downregulating the expression of sterol regulatory element-binding protein-1c, fatty acid synthase, and acetyl-CoA carboxylase. This application is the first systematic study of the comprehensive intervention effect of verbascoside on diet-induced obesity and related metabolic disorders. In an in vivo obese mouse model, it was demonstrated that verbascoside can significantly inhibit excessive weight gain induced by a high-fat diet, reduce fasting blood glucose and fasting insulin levels, improve dyslipidemia indicators including triglycerides, total cholesterol, non-esterified fatty acids, and low-density lipoprotein cholesterol, enhance insulin sensitivity, and alleviate macrovesicular steatosis and hepatocellular damage.

This invention relates to compounds of Formula I and their isotopic forms, stereoisomers, tautomers, pharmaceutically acceptable salts, pharmaceutically acceptable solvates, hydrates, prodrugs, and polymorphs. The compounds of Formula I can be used as inhibitors of proprotein convertase subtilisin 9 (PCSK9), effectively inhibiting PCSK9 activity and reducing the concentration of low-density lipoprotein cholesterol in plasma, and have good application prospects in the preparation of drugs for the treatment or prevention of cardiovascular diseases.

The utility model relates to the technical field of cholesterol detection kit, and disclose a kind of small and dense low-density lipoprotein cholesterol detection kit, including storage box, first placement component and second placement component, at least two storage grooves are set in the storage box, the first placement component and second placement component are placed in the storage box by storage groove, hinge is set at the outer side of storage box, the other end of hinge away from storage box is provided with top cover, the first placement component includes the placement groove being set in the placement frame. The small and dense low-density lipoprotein cholesterol detection kit, support seat is fixed to the both sides of hinge, when opening top cover, support top cover can keep the angle of inclination, avoid top cover after completely opening and storage box collision, anti -skid line increase the friction between support seat and table top, prevent storage box from sliding in operation, the front handle of storage box and the top handle of top cover form bidirectional gripping structure, the design of two handles, it is convenient for user to take better.

This invention relates to the field of functional product technology, and more particularly to a composition for assisting in lowering blood lipids and its application. The invention provides a composition comprising *Bifidobacterium animalis* subsp. *lactamase* MN-Gup, microalgae oil, and phytosterol esters. The composition of this invention can simultaneously and effectively reduce triglyceride and total cholesterol levels, particularly significantly reducing low-density lipoprotein cholesterol while increasing high-density lipoprotein cholesterol levels. Compared to each individual component, it exhibits significant advantages, demonstrating significant auxiliary lipid-lowering efficacy with good safety and industrial feasibility. This provides a basis for the development of auxiliary lipid-lowering products and offers a new intervention strategy for blood lipid health management.