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Depigmentation is the lightening of the skin or loss of pigment. Depigmentation of the skin can be caused by a number of local and systemic conditions. The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism).
Use of compounds as whitening compositions and depigmentation agents
The present invention relates to a whitening composition comprising a whitening effective amount of a compound of formula (I), or a tautomer, stereoisomer, hydrate, solvate, salt, or polymorph thereof, wherein R 1 、R 2 、R 3 、R 4 、R 5 、R 6 、R 7 、m and n are as defined in the specification and claims. The present invention also relates to a compound of formula (I2) or a tautomer, stereoisomer, hydrate, solvate, salt, or polymorph thereof, wherein R 1 、R 2 、R 3 、R 4 、R 5 、R 6 、and R 7 are as defined in the specification and claims. The present invention also relates to the use of at least one compound of formula (I) or any subgroup thereof, or a mixture thereof, as a depigmenting agent. The present invention also relates to the use of at least one compound of formula (I) or any subgroup thereof, or the use of a whitening composition, for preventing and / or reducing pigmentation of normal skin. The present invention also relates to the use of at least one compound, or the use of a whitening composition according to the first aspect, for reducing the amount of melanin in melanocytes, for reducing melanin synthesis, for impairing melanin transport, and / or for impairing the distribution of melanin in the upper basal layer. JPEG2026520910000038.jpg3191
Owner:ケモソンスリックス ビオサイアンス エスアー