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79 results about "Normal skin" patented technology

ANSWER. Normal skin has an even, smooth skin tone. The texture is soft and there are no visible blemishes, red spots, or flaky patches. Pores are barely visible, and the skin surface is neither greasy nor dry. Normal skin has few imperfections because of the balanced amount of water and oil, and good blood circulation.

Display device and figure skin color compensation method

The invention provides a display device and a figure skin color compensation method, and the method comprises the steps: recognizing a partition boundary through a boundary pixel difference value, dividing a face into a preset number of partitions, and screening a to-be-compensated region based on the deviation between each partition and an original skin color pixel value. According to the method, a local area with abnormal chromatic aberration caused by the illumination condition in the video frame can be accurately positioned, unnecessary adjustment of a normal skin color area is avoided, and more targeted compensation operation can be executed on a target person. According to the method, the original skin color pixel value of a normal skin color area is reserved, targeted skin color compensation is executed by dividing a plurality of face subareas, and the skin color secondary distortion phenomenon caused by executing skin color compensation on the whole face area is effectively eliminated.
Owner:VIDAA (NETHERLANDS) INT HLDG LTD

Method and equipment for detecting deflection of galvanometer motor in medical galvanometer scanning system

The invention relates to a method and equipment for detecting deflection of a galvanometer motor in a medical galvanometer scanning system. The method mainly comprises the steps that a dynamic threshold value library is established, a dynamic threshold value set matched with a current scene is called, and the dynamic threshold value set comprises an angle error threshold value, a vibration threshold value and a driver temperature threshold value; acquiring inner ring control signals in real time, wherein the inner ring control signals at least comprise a motor angle error signal, a vibration signal and a driver temperature signal; carrying out quantitative fusion on the collected signals through a multi-signal weight fusion algorithm and carrying out preliminary judgment; and comparing the preliminarily judged signals with a dynamic threshold group, judging whether each signal meets a corresponding threshold condition or not, and if all the signals meet the corresponding threshold condition, judging that the galvanometer motor deflects in place. Compared with the prior art, the precision is remarkably improved, the normal skin burn risk caused by position deviation is avoided, and the high-precision safety requirement of a medical scene is met.
Owner:BEIJING SANO LASER S&T DEVELOPMENT CO LTD

Application of glycyrrhizic acid in preparation of external product for preventing and treating acne and gel for preventing and treating acne

The invention relates to the technical field of acne prevention and treatment, in particular to application of glycyrrhizic acid in preparation of an external product for preventing and treating acne and gel for preventing and treating acne. Research finds that glycyrrhizic acid not only can generate an anti-inflammatory effect, but also can repair a mechanical barrier of skin, and has no adverse effect and no irritation on normal skin, so that glycyrrhizic acid can be used as an active substance for preparing an external product for preventing and treating acne. The gel for preventing and treating acne provided by the invention is prepared from carbomer, xanthan gum, triethanolamine, glycerol, 1, 3-butanediol, propylene glycol, glycyrrhizic acid and other raw materials, has the advantages of good stability, uniform texture, good spreading property and the like, has relatively strong hygroscopicity and moisture retention, can keep a certain degree of hydration of skin, promotes skin barrier repair, and has a good anti-acne effect. The composition is suitable for preventing and treating acne.
Owner:SHANXI UNIV OF CHINESE MEDICINE

Wart body cutting device

InactiveCN120616700AExcision instrumentsMedical applicatorsWart removalMEDICATION DISPOSAL
The invention discloses a wart excision device which combines wart excision and medicine spraying functions, can immediately perform medicine treatment after wart excision, effectively promotes wound healing, reduces infection risk, reduces the possibility of wart recurrence, and improves thoroughness and durability of treatment. And secondly, the operation design of the device is extremely humanized, and the patient can operate the device at home without going to a hospital or a professional medical institution, so that the time and economic cost are greatly saved, and meanwhile, the psychological burden and anxiety mood of the patient caused by seeing a doctor are also relieved. The design of the adjustable blade assembly and the straight blade is adopted by the device, the cutting mode can be flexibly adjusted according to the shape and size of warts, accurate excision is achieved, damage to surrounding normal skin is reduced to the maximum extent, and therefore the pain feeling is reduced, and the size of wounds is reduced. In addition, the medicine applying assembly of the device can accurately spray medicine to the wound surface, pain is further relieved, and rapid healing of the wound is promoted.
Owner:HUZHOU CHINESE MEDICINE HOSPITAL

Traditional Chinese medicine decoction for treating vitiligo and preparation method thereof

PendingCN121944013Arestore normal skin colorResolve black and white contrastDermatological disorderPlant ingredientsLedebouriella seseloidesMedicinal herbs
The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine decoction for treating vitiligo and a preparation method thereof.The traditional Chinese medicine decoction for treating vitiligo is prepared from ten medicinal materials including notopterygium root, divaricate saposhnikovia root and the like according to the core pathogenesis of vitiligo rheumatism stagnated heat syndrome, the brand new theory of treating both black and white diseases and both black and white diseases is creatively provided, and on the basis of the theory, the traditional Chinese medicine decoction for treating vitiligo is prepared into the traditional Chinese medicine decoction for treating vitiligo. White spots and surrounding deepened skin are brought into systematic conditioning for the first time, the formula is compatible with black and white medicine pairs, black is used for treating white, white is used for treating black, overall conditioning and two-way adjustment are achieved, the white spots can recover to the normal skin color, and due to the innovative application of the two groups of black and white medicine pairs (wine-processed rhizoma chuanxiong, radix angelicae sinensis, radix rehmanniae preparata and radix paeoniae alba) in the formula, black is used for treating white, white is used for treating black, and two-way adjustment is achieved. And meanwhile, the clinical piebald skin disease symptom is also eliminated, so that the white spots recover to the normal skin color.
Owner:SHANDONG HUAHAI VITILIGO RESEARCH INSTITUTE

Novel targeted ultraviolet light therapeutic instrument for vitiligo

The utility model provides a vitiligo novel target ultraviolet light therapeutic instrument, relates to skin treatment equipment technical field, including base, console, adjusting tube and phototherapy head, the console is installed on the base, the adjusting tube connects the console and the phototherapy head, the phototherapy head is provided with ultraviolet light source inside, and the ultraviolet light source is connected with the base. The front end of the phototherapy head is provided with an adjustable light shield, so that the problems that the irradiation range of the phototherapy head cannot be adjusted, a vitiligo disease area is not targeted, and surrounding normal skin can be irradiated in the use process of an existing ultraviolet light therapeutic apparatus can be solved; and the problems that the irradiation position and angle are not easy to fix when a traditional handheld phototherapy head is used for irradiation, and the phototherapy head is directly contacted with the skin due to mistaken touch are solved.
Owner:YUNNAN DERMATOLOGY HOSPITAL CO LTD

A portable wound treatment and cleaning device for general surgery

The present invention relates to the technical field of medical devices, and particularly relates to a portable wound treatment and cleaning device for general surgery, which includes a support block for fitting to the skin. A number of mounting blocks are slidably fitted on the top of the support block. A ball screw mechanism for driving the movement of the mounting blocks is provided on the mounting blocks. A pressing mechanism for flushing the wound is slidably fitted at the bottom of the mounting block; one end of the pressing mechanism away from the mounting block is hinged with a contact block. An infrared temperature sensor for measuring the skin temperature is fixedly connected to the bottom of the contact block. The infrared temperature sensor is electrically connected to a control panel for distinguishing normal skin and the wound area based on the skin temperature. The control panel controls the ball screw mechanism based on the skin temperature to drive the pressing mechanism to contact the wound area; a spraying mechanism for spraying disinfectant on the wound area is provided at the bottom of the contact block. Compared with the prior art, the present invention can replace manual cleaning and disinfection of wounds, improve the treatment efficiency, and reduce the probability of wound infection.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Abdominal cavity sealing dressing capable of displaying temperature and humidity

The utility model relates to an abdominal cavity sealing dressing capable of displaying temperature and humidity. The abdominal cavity sealing dressing comprises a polyurethane layer, a humidity sensor, a hardened layer, a pressure sensor, a temperature sensor and a hemostasis layer, the humidity sensor is arranged on the side, attached to the skin, of the polyurethane layer. The abdominal cavity sealing dressing capable of displaying the temperature and the humidity is of a multi-layer composite structure, the dressing is provided with a signal module and used for wireless transmission of temperature and pressure data and monitoring of the internal condition of the abdominal cavity, the device is structurally similar to human normal skin, and the innermost chitosan hemostasis layer is similar to a subcutaneous tissue layer; the effect of protecting internal tissues and organs is achieved; the middle layer comprises a sensor which can reflect partial key indexes of the abdominal cavity and is similar to a neuroreceptor part; the outer layer is good in mechanical performance, can resist external mechanical injuries and is similar to a skin layer, the effect similar to the skin can be achieved through the bionic structure, and treatment of the open abdominal wall trauma is more efficient and intelligent.
Owner:CHINESE PEOPLES LIBERATION ARMY ARMY 83RD GRP MILITARY HOSPITAL

A monkeypox virus classification method and device based on image comparison and a storage medium

The application belongs to the technical field of image recognition, and discloses a monkeypox virus classification method and system based on image comparison and a storage medium, which comprises an individual reference modeling module, collects normal skin and initial lesion images of a healthy side of a patient, generates a healthy texture template and an initial lesion reference library, performs gray scale normalization on the healthy texture template and the initial lesion reference library through adaptive histogram stretching, and outputs a comparison reference image group; a symptom density quantification module, acquires a current monitoring image of the patient, segments a lesion area in combination with the comparison reference image group, extracts layered features of the lesion area to generate a three-dimensional symptom density vector, extracts texture roughness of a surface of the lesion area, and constitutes a lesion quantification data set; the accuracy of disease monitoring is improved, and a clinical nursing process is optimized.
Owner:BEIJING YOUAN HOSPITAL CAPITAL MEDICAL UNIV

Foam dressing device capable of adding medicine

The foam dressing is mainly used for protecting a wound surface after dressing change, a disposable traditional dressing patch needs to be replaced after dressing change every time, the consumable cost is increased, and due to the fact that the dressing patch is prone to being adhered to the wound, secondary damage to the normal skin of a patient and the wound surface of the wound can be caused by tearing the foam dressing when the wound is replaced. The foam dressing device capable of adding the medicine comprises a commercially available foam dressing basic patch, a medicine adding device and a sealing layer, the medicine adding device and the sealing layer are arranged in the foam dressing basic patch, and the foam dressing basic patch is sequentially composed of a water blocking layer, a foam layer, a bonding layer and an anti-adhesion layer structure. According to the technology, during secondary dressing change, the whole foam dressing patch does not need to be taken down or replaced, dressing change operation can be completed only by adding medicine through the medicine adding opening, consumables and related expenses are saved, and the technology is simple and convenient to operate. Damage to normal skin or wounds caused by replacement and tearing of the foam dressing is reduced, and wound healing can be promoted through the comprehensive effect.
Owner:LANZHOU WENHE MEDICAL EQUIP RES & DEV CO LTD

Medical image recognition method and system based on optical attenuation coefficient

The invention belongs to the field of medical imaging processing, and particularly relates to a medical image recognition method and system based on an optical attenuation coefficient. According to the method, high-precision classification is realized by fusing an optical attenuation coefficient (OAC) image and a probability density function (PDF) feature. According to the technical scheme, the method comprises the steps that skin three-dimensional OAC data are obtained through an SD-OCT device, unsupervised noise reduction is conducted through a 3D-Unet network, and image leveling and cutting are achieved in combination with Canny edge detection and linear fitting; counting OAC value distribution and extracting the peak value, distribution width and other characteristics of the PDF; and constructing a joint learning model, fusing the two-dimensional image features extracted by the ResNet34 and the one-dimensional PDF features extracted by the full-connection network, and outputting probabilities of AK, BCC and normal skin through a Softmax classification layer. The method has the advantages of being non-invasive and high in automation degree, the problem that similar lesion distinguishing is fuzzy is effectively solved, the classification accuracy is remarkably improved, and a standardized technical means is provided for early screening of skin cancer.
Owner:MICORO (SHANGHAI) INTELLIGENT TECH CO LTD

Use of bioactive protein in preparation of drug for treating herpes virus infection and pharmaceutical composition for treating herpes virus infection

PCT designated stageWO2026036538A1Peptide/protein ingredientsAerosol deliveryHerpesvirus infectionHerpes zoster virus
Provided are use of a bioactive protein in the preparation of a drug for treating herpes virus infection and a pharmaceutical composition for treating herpes virus infection. The pharmaceutical composition mainly comprises a bioactive protein, a matrix, a humectant, a pH regulator, and a preservative. The present invention has the following technical effects: 1) By means of a large amount of research and experimental verification, the inventors have discovered for the first time that anhydridized lactoferrin, a modified bioactive protein, has an inhibitory effect on herpes zoster virus (VZV). 2) In the pharmaceutical composition, the type and amount of excipient and the proportion of the main ingredient are reasonable. The pharmaceutical composition is administered in ointment form, in spray form, or in other dosage forms suitable for external use, has a significant therapeutic effect, has small local toxic side effects, has very low acute dermal toxicity, causes no irritation or allergy, does not interfere with normal skin functions, and is safe and effective.
Owner:CHANG TIANAN +1

Wound intelligent identification and evaluation method for burn plastic nursing

The invention relates to the field of patient burn image recognition, in particular to an intelligent wound recognition and evaluation method for burn plastic nursing. Normal color feature data are obtained through color space features of normal skin; obtaining a pixel point color parameter by combining the difference between each pixel point of the sliding window on the burn area and a normal skin pixel point; obtaining a second-order chromatic aberration according to parameter differences between the pixel points in the sliding window and other pixel points; dividing the image into different color areas; analyzing the overall region edge distance of the regions with different colors, and further obtaining a burn evaluation coefficient; and intelligently identifying the wound according to the coefficient. The method can adapt to the complexity of a burn wound, and intelligently identifies and evaluates the burn recovery condition of a patient in time.
Owner:THE FIRST AFFILIATED HOSPITAL OF XIAN MEDICAL UNIV

Medical patch

The application aims to provide a medical patch, which comprises a tearable film layer for being torn under external force, a gel layer connected with the tearable film layer and containing a skin external medicine, and the like. The gel layer is provided with a plurality of cross-distributed segmentation grooves to form a plurality of gel blocks, and the tearable film layer is provided with a tear line groove. Compared with the prior art, the application can facilitate the adhesion to the affected area and reduce the area of the region with the medicine component contacting the normal skin.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE

Soluble microneedle patch for skin tumor as well as preparation method and application of soluble microneedle patch

The invention discloses a soluble microneedle patch for skin tumors and a preparation method and application thereof, and belongs to the technical field of soluble microneedles, gel formed by a microneedle matrix which is excellent in biocompatibility and contains disulfide bonds is injected into a microneedle mold, and the soluble microneedle patch is prepared. Then vacuumizing, centrifuging, adding viscous microneedle substrate polyacrylic acid gel, and drying to obtain the specific soluble microneedle patch of which the dissolution rate in a tumor microenvironment is obviously higher than that of normal tissues. The microneedle matrix with disulfide bonds specifically responds to the high reducibility of a tumor microenvironment, the drug is rapidly broken and released, the drug release amount in a normal skin area is reduced, stimulation to healthy tissue is avoided, potential damage to normal tissue is reduced, and more accurate targeted therapy is achieved.
Owner:NANJING TECH UNIV

Application of compound in preparation of scar relieving agent and external scar removing agent

The invention belongs to the technical field of skin wound repair, and particularly relates to application of a compound in preparation of a scar relieving agent and an external scar removing agent. According to anti-scar traditional Chinese medicine prescription analysis and component and activity research, daucosterol, shikonin, przewalskin C and 4-ethoxyformyl-quinol-2-ketone have the effects of inhibiting proliferation of human keloid fibroblasts and inhibiting collagen synthesis of human normal skin fibroblasts induced by TGF-beta1; the composition has a scar relieving effect on scars of scar animal models, and can be used as a scar relieving agent, especially an external preparation applied to local skin. The invention further discloses an external scar-removing agent, namely an emulsion-type liniment, the main component of the external scar-removing agent contains silicone oil and also contains any one of an antioxidant and / or daucosterol, shikonin, przewalskin C and 4-ethoxyformyl-quinoline-2-ketone, and the main component has a better effect of relieving scars of a scar animal model when being externally applied to local skin.
Owner:HEILONGJIANG LONGDE PHARMA CO LTD +1

An epidermal repair gel dressing and method of making same

The present application provides a kind of epidermis repair gel dressings and its preparation method, it is related to dressing field.The epidermis repair gel dressings includes repair liquid, 100 parts of the repair liquid includes composite sodium hyaluronate 0.1-0.3 parts, carbomer 0.02-0.06 parts, glycerol 1-4 parts, pentanediol 1-3 parts, composite acid 0.05-0.1 parts, composite peptide 0.01-0.03 parts and the balance purified water by weight parts;The composite sodium hyaluronate is composed of sodium hyaluronate, hydrolyzed sodium hyaluronate and sodium hyaluronate crosslinked polymer;The composite acid is prepared from ursolic acid, hydroxyl asiatic acid, lipoic acid;The composite peptide is prepared from thirteen peptides and palmitoyl pentapeptide-3.The epidermis repair gel dressing of the present application has better repair effect on acne lesions, not only inhibits active propionibacterium acnes, but also can reduce the expression of inflammatory factors, can deeply repair damaged basal structure, maximumly reduce the degree of acne lesions, and restore to close normal skin.
Owner:TIBET YUANRONG PHARMACEUTICAL CO LTD

Use of DPP4 in treatment or diagnosis of inflammatory skin diseases characterized by skin barrier damage

The invention belongs to the technical field of biology, and particularly relates to application of DPP4 in treatment or diagnosis of inflammatory skin diseases characterized by skin barrier injury. According to the application disclosed by the invention, key effects of dipeptidyl peptidase-4 (DPP4) in regulating and controlling keratinocyte differentiation and maintaining normal skin barrier structures and functions are analyzed, and on the basis of AAV-mediated skin tissue keratinocyte DPP4 gene therapy, the conditions of abnormal epidermis thickening and abnormal differentiation caused by skin damage can be relieved by inducing normal differentiation of keratinocytes, so that the curative effect of the skin tissue keratinocyte DPP4 is improved, and the curative effect of the skin tissue keratinocyte DPP4 is improved. The traditional Chinese medicine composition provided by the invention can be used for promoting the repair of an epidermal barrier and improving and maintaining the steady state of the skin barrier so as to effectively improve psoriasis-like dermatitis, and a new scheme is provided for treating inflammatory dermatosis characterized by skin barrier injury. In addition, the expression level of DPP4 can be used as a diagnostic marker for inflammatory skin diseases characterized by skin barrier injury.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

A Skin Lesion Segmentation Method Based on Error Localization and Adaptive Optimization

The present invention relates to a skin lesion segmentation method based on error localization and adaptive optimization. First, the skin lesion images captured by dermoscopy and the corresponding segmentation labels are divided into a training set, a validation set, and a test set. Then, a segmentation network is constructed, and the constructed segmentation network is trained using the training set. During the training process, the generalization ability of the segmentation network is continuously monitored through the validation set, and finally, a trained segmentation network is obtained. Finally, the test set is input into the trained segmentation network, and the segmentation result of the skin lesion is output. The skin lesion segmentation method based on error localization and adaptive optimization of the present invention effectively focuses on the key areas that need to be optimized in actual training, helps the model more accurately understand and distinguish the characteristics of lesions and normal skin, thereby improving its segmentation ability when dealing with complex lesions such as fuzzy boundaries, complex shapes, and background noise.
Owner:DONGHUA UNIV

Antibacterial leakage-proof patch for stoma and preparation method of antibacterial leakage-proof patch

The invention relates to the field of medical paste dressings and stoma nursing materials, in particular to an antibacterial leakage-proof patch for stoma and a preparation method of the antibacterial leakage-proof patch. The invention aims to solve the technical problems that the antibacterial durability is insufficient, a biological membrane is easy to form and the micro-ecological balance of skin is damaged. The prepared patch is composed of a back lining layer, an absorption layer, a pH responsive antibacterial layer and a release layer which are sequentially stacked from top to bottom. Wherein the pH responsive antibacterial layer contains a pH responsive microcapsule loaded with an antibacterial agent; the wall material of the microcapsule can be dissolved in an alkaline environment, and the core material is a nano-silver and chitosan quaternary ammonium salt composite antibacterial agent. When the local environment is changed from weak acidity to alkalinity due to infection of the skin around the stoma, the microcapsules are rapidly swelled and broken, high-concentration nano-silver and chitosan quaternary ammonium salt are released, and the bactericidal effect is achieved; under the weak acid condition, the antibacterial agent in the microcapsule is only slowly and continuously released, the basic antibacterial effect is maintained, and normal microbial flora balance of the skin is protected.
Owner:HUBEI HENDRY MEDICAL EQUIP CO LTD

Phototherapy light chopper

The utility model belongs to the technical field of medical instruments, and particularly relates to a phototherapy light chopper which comprises a light shading plate. The shading plate is of a plate-shaped structure; the shading plate is provided with a flange, a concave edge and a straight edge; the light shielding plate comprises an outer layer, a light shielding layer and a contact layer; one side of the shading layer is fixedly connected with the outer layer, and the other side of the shading layer is fixedly connected with the contact layer; a first anti-skid structure is arranged on one side, far away from the shading layer, of the outer layer; a second anti-skid structure is arranged on the side, away from the shading layer, of the contact layer. The beneficial effects of the utility model are that: when in use, the plurality of shading plates surround the outer side of the part of a patient needing to be treated to form an annular light-proof layer so as to prevent normal skin from being irradiated; according to the shape of a to-be-treated part of a patient, the flange, the concave edge or the straight edge of the shading plate can be freely selected to face the patient, and the shading plate can adapt to all patients and is convenient to use.
Owner:SICHUAN ACADEMY OF MEDICAL SCI SICHUAN PROVINCIAL PEOPLES HOSPITAL

A mixture of artemisia extract and rosemary extract, method of preparation and use

This invention discloses a mixture of artemisia annua extract and rosemary extract and its application in the field of dermatology. The invention provides a mixture of artemisia annua extract and rosemary extract, a preparation method, and applications. This mixture can regulate the function of macrophages and epidermal cells, enhancing the phagocytic capacity of macrophages and initiating normal skin immune defense. Simultaneously, it can inhibit the overexpression of inflammatory factors, increase the expression of tight junction proteins in epidermal cells, and restore the skin barrier.
Owner:SHANGHAI JIAOTONG UNIV +1

Compositions and methods for use of CDC42 inhibitors in the treatment of skin disorders

A pharmacological agent and method for treatment of cancer and vascular-related disorders of skin and colon are described. The pharmacological agent, which is a small molecule that targets and inhibits both RhoJ and CDC42 signaling, demonstrates potent anti-vascular effects in normal skin, colon, and tumors, combined with low toxicity, especially as compared to BRAF inhibitors (such as, vemurafenib used in melanoma treatments), selective CDC42 inhibitors (such as CASIN), and VEGF inhibitors (known as anti-vascular agents, such as, for example, linifanib). As such, the pharmacological agent is particularly suited for applications related to treating cancer, as well as disorders of the skin and colon that exhibit increased vasculature.
Owner:RGT UNIV OF CALIFORNIA +1

Modified chitosan oligosaccharide, composite decontamination preparation and preparation method thereof

The invention relates to modified chitosan oligosaccharide, a composite decontamination preparation and a preparation method thereof, and belongs to the technical field of nuclide decontamination and daily chemicals. The raw materials mainly comprise AESA, OP-10, K12A, APG1214, LAO-30, modified chitosan oligosaccharide and the like. The modified chitosan oligosaccharide is carboxymethyl chitosan oligosaccharide, the water solubility is improved after modification, and tests show that the material has a good function of removing radionuclides from human skin. According to the compound decontamination preparation, actinide nuclide decontamination and cobalt and cesium decontamination efficiency verification proves that the decontamination efficiencies in 6-hour and 12-hour experimental groups respectively reach 85% and 65% or above. Skin stimulation experiments of the decontamination liquid prove that the decontamination liquid has no stimulation or damage to normal skin of a human body. A skin sensitization test proves that the guinea pig skin sensitization reaction grade is 0. The invention is mainly applied to emergency decontamination of radionuclide.
Owner:CHINA INST FOR RADIATION PROTECTION

Drug-loaded patch for photodynamic treatment of skin diseases and preparation method of drug-loaded patch

The invention discloses a drug-loaded patch for photodynamic treatment of skin diseases and a preparation method of the drug-loaded patch, and relates to the technical field of medical treatment. Comprising the following steps: extracting a two-dimensional lesion pattern of a skin surface disease area; and printing the photosensitizer drug solution onto the patch by taking the two-dimensional lesion pattern as a printing mother set to obtain the drug-loaded patch for photodynamic treatment of skin diseases. The medicine carrying patch can accurately act on a lesion area in a skin disease area, accurate delivery and positioning of medicine are achieved, the bioavailability of photosensitizer medicine is improved to the maximum extent, the clinical use cost is reduced, and normal skin tissue in the disease area is prevented from being interfered by all-directional medicine smearing. During illumination, the photodynamic therapy process is completely concentrated in a lesion area, additional shading treatment is not needed, the normal healthy skin can be effectively prevented from being affected by photodynamic therapy, and the side effects of photodynamic therapy and drugs are reduced.
Owner:SHENZHEN UNIV

Visual negative pressure drainage dressing and negative pressure suction device

The utility model discloses a visual negative pressure drainage dressing and a flushing negative pressure suction device, the visual negative pressure drainage dressing comprises a self-adhesive medical film and a foam drainage material, the self-adhesive medical film and the foam drainage material are of an integrated structure, and the visual medical dressing is provided with a drainage window and an observation window; when the visual medical dressing is used, after the protective paper is torn off and removed, the visual medical dressing is pasted to normal skin around a wound to form a closed wound treatment cavity; the foam drainage material is arranged in the mounting cavity, and a first through hole and a second through hole are formed in the foam drainage material; the flushing pipe penetrates through the drainage window and then is arranged at the bottom of the foam drainage material; and the negative pressure suction tube is arranged on the flushing tube in a sleeving manner. Due to the integrated design, the medical negative pressure drainage dressing is transparent and visual, medical staff can conveniently observe changes of a wound surface at any time, and the negative pressure drainage dressing can be used for rapidly installing and sealing the wound surface and rapidly installing and washing a drainage tube.
Owner:GUANGDONG MEIJI BIOTECH

Medical aesthetic special integrated nanorobot system

PendingCN122320469AHuman bodyIrritation
This invention discloses an integrated nanorobot system for medical aesthetics, belonging to the field of minimally invasive and non-invasive diagnostic and treatment technology in civilian medical aesthetics. The system uses glucose-modified PCL with a glucose grafting rate of 20-25 wt% as its core substrate, adaptable to a particle size range of 100-200 nm (median 150 nm). It is a non-disassembly integrated structure with a γ-polyglutamic acid modification layer on the main surface. It embeds six functional units: precise skin detection, precise drug delivery, minimally invasive ablation, repair and regeneration, pore cleansing, and safety regulation. Each unit communicates with the safety regulation unit via carbon nanotube nano-conduction links. The safety regulation unit and the γ-polyglutamic acid modification layer work together through specific logic to construct a pH dual-redundancy control logic specific to medical aesthetic scenarios. The false trigger rate on normal skin is ≤0.05%, cytotoxicity and mucosal irritation are both grade 0, and the degradation cycle is 14±2 days. The system has a mature and reproducible manufacturing process, with a yield rate of ≥93% in 100g-level small-scale preparation. All performance indicators meet the authoritative standards of FDA / ISO medical aesthetic devices. It is specifically designed for superficial medical aesthetic repair of the human epidermis / mucous membranes, solving the technical pain points of traditional medical aesthetic devices such as single function, low precision, and many complications. It realizes a one-stop closed-loop operation of "detection-treatment-repair" and has strong clinical applicability.
Owner:高爽

Wound care gel with double-effect repair functions of healing promotion and scar inhibition and preparation method thereof

The invention relates to the technical field of gel, in particular to wound nursing gel with double-effect repair functions of healing promotion and scar inhibition and a preparation method of the wound nursing gel. According to the preparation method disclosed by the invention, through the mutual cooperation of the modified astragalus polysaccharide, namely the precise navigation of a conjugate formed by collagen targeting peptide-astragalus polysaccharide, the deep anti-inflammatory regulation of dipotassium glycyrrhizinate and the high-quality template guidance of recombinant humanized III-type collagen, the traditional passive repair is upgraded to active guided repair; the contradiction between the healing speed and the healing quality is coordinated from the source. According to the invention, the wound closure can be obviously accelerated (the early healing rate is improved by about 3 times), and scars can be inhibited fundamentally. Experiments prove that the proportion of type III collagen of new dermis can be increased to be close to the normal skin level (about 42%), and collagen fibers are highly ordered in arrangement (the orientation degree reaches 0.91), so that physiological regeneration instead of pathological scar repair in a real sense is realized.
Owner:GUANGXI XINYE BIOLOGICAL TECH

Breathable sewing-free adhesive tape

The utility model belongs to the technical field of sewing-free adhesive tapes, and discloses a breathable sewing-free adhesive tape which comprises a non-woven fabric, an acrylate layer is arranged at the bottom end of the non-woven fabric, a release layer is arranged below the acrylate layer, the top end of the release layer is connected with the acrylate layer through a pressure-sensitive adhesive, and dry adhesive tapes are arranged on the left side and the right side of the top end of the non-woven fabric. The non-woven fabric and the acrylate layer adopted by the adhesive tape have good air permeability, the breathing effect of a wound and normal skin around the wound can be guaranteed, the skin cannot be soaked, the viscosity of the adhesive tape cannot be affected, the adhesive tape has good comfort, and the adhesive tape is convenient to use and obvious in effect; the non-woven fabric can replace a doctor to suture a surgical incision, the pain of a patient is reduced, the strength of the non-woven fabric is improved through acrylic ester, imported non-woven fabric is replaced, and the product cost is reduced.
Owner:JINZHIDA MEDICAL EQUIPMENT (SHANGHAI) CO LTD