276 results about "Normal skin" patented technology

A composition containing enhanced colloidal oatmeal which utilizes other avena sativa ingredients to neutralize the discomfort, irritation and inflammation of the skin, as well as maintaining normal skin, and can be used to treat many types of discomforts, including itching; due to poison ivy, oak and sumac, insect bites, sunburn, chicken pox, hives, prickly heat, chafing, and the like while maintaining the normal pH of the skin.

Skin lightening / even toning compositions are provided for reducing skin pigmentation of normal skin and for lightening hyper-pigmented skin said compositions comprising (i) highly purified hexylresorcinol which is substantially free or resorcinol, (ii) optionally, at least one other skin lightening agent, and (iii) a dermatologically acceptable carrier.

The present invention provides a delivery system and method to deliver topically homeopathic amounts of at least one Homeopathic Complex. It further provides a Homeopathic Colored Pigment Product containing a coloring agent having a plurality of particles having at least one surface and a homeopathically effective amount of at least one Homeopathic Complex, wherein the at least one surface of particles in the plurality of particles of the coloring agent contains the at least one Homeopathic Complex. It also provides cosmetic formulations containing the Homeopathic Colored Pigment Product for normal skin, problem skin, aged skin, and skin damaged by the harmful rays of the sun.

The invention provides a near-infrared spectrum imaging system for diagnosis of depth and area of burn skin necrosis. The near-infrared spectrum imaging system comprises a spectrum imager and a computer-control system. The spectrum imager acquires 1100-2500nm waveband spectral signals of burn skin necrosis tissue of a target area, the spectral signals are subjected to image analyzing and processing through the computer-control system, the depth and area of burn of the target area can be acquired through spectral matching recognition upon a spectral reflectance curve corresponding to each image element in spectral images and a standard spectral reflectance curve in a burn skin necrosis spectral database in a data module and are synthesized into three-dimensional image display of the target area. By the near-infrared spectrum imaging system, the spatial structure of skin changed due to tissue protein denaturation before and after the skin burn can be specified, so that micron-level information about boundaries of normal skin tissue and necrotic tissue and the depth of burn skin necrosis can be provided visually, and clinical diagnosis, treatment and prognosis judgment can be supportively facilitated.

A non-invasive tool for skin disease diagnosis would be a useful clinical adjunct. The purpose of this study was to determine whether visible / near-infrared spectroscopy can be used to non-invasively characterize skin diseases. In-vivo visible- and near-infrared spectra (400-2500 nm) of skin neoplasms (actinic keratoses, basal cell carcinomata, banal common acquired melanocytic nevi, dysplastic melanocytic nevi, actinic lentigines and seborrheic keratoses) were collected by placing a fiber optic probe on the skin. Paired t-tests, repeated measures analysis of variance and linear discriminant analysis were used to determine whether significant spectral differences existed and whether spectra could be classified according to lesion type. Paired t-tests showed significant differences (p<0.05) between normal skin and skin lesions in several areas of the visible / near-infrared spectrum. In addition, significant differences were found between the lesion groups by analysis of variance. Linear discriminant analysis classified spectra from benign lesions compared to pre-malignant or malignant lesions with high accuracy. Visible / near-infrared spectroscopy is a promising non-invasive technique for the screening of skin diseases.

A composition and a method of producing a composition which simulates hydration, cleansing and other properties of native vernix. The composition contains, in one embodiment, hydrated synthetic cells in a lipid matrix to provide properties which are substantially similar to those of native vernix, and may also contain proteins. In one embodiment, the composition contains water-in-oil emulsified particles providing water vapor transport and evaporative water loss properties simulating native vernix. In one embodiment, the composition contains cubosomes / water with up to 30% protein and about 5% lipid to about 30% lipid. The composition may be used to cleanse newborn skin, compromised skin surfaces, as well as normal skin, to provide hydration / barrier function, and other applications.

A micro-Raman spectrometer system for use in differentiating tumor lesions from normal skin detects specific characteristics of Raman spectra indicative of cancer. A peak at 899 cm−1 and a higher intensity region in the 1325 cm−1 to 1330 cm−1 range indicate the presence of tumors. The spectrometer system may be applied for skin cancer detection and for mapping the margins of lesions. Cancer detection methods as described herein have achieved diagnostic sensitivity of 95.8% and specificity of 93.8%.

The invention discloses scald and burn dressing prepared by a coaxial electrostatic spinning method. The scald and burn dressing is a nanofiber membrane with a core / shell structure, wherein the shell is made of a natural biological high molecular material and the core is a degradable synthetic high molecular material loaded with astragaloside. The mass ratio of astragaloside to the degradable synthetic high molecular material is 1:(2-50). The invention further discloses a preparation method of the scald and burn dressing. The raw materials are easy to get and cheap, and the preparation process is simple, easy to operate and control and can be easily put into large-scale industrial production. The prepared scald and burn dressing has good flexibility and high mechanical strength, and can form a protective fiber felt on the surface of the wound to promote growth of normal skin tissues and reduce formation of scar tissues, thereby curing skin injury.

The invention relates to the technical field of a traditional Chinese medicine preparation, and particularly discloses externally-applied skin-generating oil for treatment of burns and a preparation method and application thereof. The skin-generating oil is prepared by soaking the following 15 Chinese herbs in sesame oil: radix scutellariae, rheum officinale, astragalus mongholicus, coptis chinensis, cortex phellodendri, angelica sinensis, sanguisorba officinalis, lithospermum, rehmannia, radix angelicae, cynanchum atratum, bletilla striata, olibanum, myrrh and borneol. When the skin-generating oil is applied in treatment of burns, wound infection caused after injury can be prevented effectively, proliferation and migration of fibroblasts and vascular endothelial cells can be promoted, neovascularization can be induced, wound healing can be accelerated, scar repair can be promoted, the wound healing time can be shortened, Class I-II burns can be cured in 10-12 days, and Class III burns of rabbits can be cured in 20-25 days. When Class III burns of rabbits are treated with the skin-generating oil, the wound area can be reduced from 6 cm<2> to 0.1cm<2>, the wound surface is flat, smooth and soft, and newborn hair is normal. The wound epidermis can be recovered completely, dense hair follicles can be formed in the dermis layer, and almost no difference from normal skin tissues can be produced.

The NSAID, sulindac and / or its metabolites and derivatives, in combination with hydrogen peroxide or another oxidizing agent, such as arsenic trioxide that generates reactive oxygen species (ROS), significantly enhances the killing of cancer cells. This effect occurs at concentrations of each compound that individually have little or no activity directed against cancer cells. A skin cream has been developed and used to treat skin cancer and precancerous skin growths that effectively removes the lesions with no effect on surrounding normal skin.

For determining autofluorescence of a clinically normal skin issue (7) of a patient, the tissue (7) is irradiated with electromagnetic radiation. An amount of fluorescent radiation emitted by the tissue (7) in response to the irradiation is measured and, in response thereto, a signal is generated which represents a determined autofluorescence in agreement with the measured amount of electromagnetic radiation. Because the tissue (7) is skin tissue (7) in vivo and irradiation is performed noninvasively, a method which is very simple to apply for determining autofluorescence is obtained. An apparatus especially adapted for use in this method is also described.

The invention discloses a method for detecting and grading greening potatoes based on machine vision. The method comprises the following steps of: (1) collecting a complete potato image and filtering a background to obtain a potato split image; (2) calculating a figure center of a potato and removing a potato outline in proportion by taking the figure center as a standard; (3) scanning a target region of the potato and calculating an H value point by point; (4) comparing the calculated H value with a threshold value alpha, wherein if the H value is equal to the threshold value alpha, a pixel point is taken as a greening point, but if not, the pixel point is taken as a normal skin point; and (5) setting the threshold value and counting the quantity of greening points, and comparing the greening points with a threshold value beta for grading the potatoes. The method disclosed by the invention is low in computation complexity and easy to realize, is applicable to rapid and real-time grading of the potatoes, is strong in objectivity and high in efficiency, and has very good application prospect.

The invention belongs to aircraft assembly automation technology and relates to a normal angle measuring unit for measuring surface normal skin workpieces in real time. The unit comprises a support plate, a universal mechanism fixing ring, a universal mechanism outer ring, a displacement sensor, a measuring contact end, a measuring plate and a reset spring. The normal angle measuring unit is exquisite in structural design, due to the fact that surface radian of skin workpieces changes along with positions, the normal adjusting unit can automatically adapt to the radian changes on the skin surfaces, deviation value between actual normal and theoretical normal can be measured in real time, deviation angle of the actual normal and the theoretical normal can be adjusted into a preset range according to the deviation value, and perforation normal precision can be guaranteed. By the surface perforation normal measuring unit using the displacement sensor for online measuring, normal deviation of cutter axes and skin surfaces can be adjusted in real time, and perforation quality of skin workpieces can be guaranteed.

A composition and a method of producing a composition which simulates hydration, cleansing and other properties of native vernix. The composition contains hydrated synthetic cells in a lipid matrix to provide rheological properties which are substantially similar to those of native vernix, and may also contain proteins. In one embodiment, the composition contains cubosomes / water with up to 30% protein and about 5% lipid to about 30% lipid. The composition may be used to cleanse newborn skin, compromised skin surfaces, as well as normal skin, to provide hydration / barrier function, and other applications.

The invention discloses a mesenchymal stem cell biological winkle removing agent and a preparation method thereof. The winkle removing agent is prepared by uniformly mixing mesenchymal stem cells, recipient blood plasma, growth factors, insulin and hyaluronic acid. The preparation method comprises the following steps of: (1) collecting and culturing the mesenchymal stem cells to prepare cell concentrated solution; (2) collecting the recipient blood plasma; (3) adding the growth factors and the insulin into the recipient blood plasma; and (4) using the hyaluronic acid as a biologic scaffold, and repeatedly sucking and uniformly mixing 2 percent hyaluronic acid, the blood plasma into which the growth factors and the insulin are added and the mesenchymal stem cell concentrated solution in aninjector to obtain a mesenchymal stem cell preparation. The winkle removing agent prepared by the method is used for removing and preventing skin winkles and has the advantages of quick response, long maintenance time, non-stiff facial expression, unobvious hardening of hyperplastic tissues and skin texture accordant with normal skin.

The invention discloses tissue engineering skin which comprises seed cells and an acellular allogenic dermal matrix, wherein the seed cells and the acellular allogenic dermal matrix form a skin appendage; the seed cells are arranged, spread flat and printed at corresponding positions on the front side of the acellular allogenic dermal matrix according to an anatomical structure of normal skin by using a 3D (Three-dimensional) printer. The invention also discloses a method for preparing the tissue engineering skin. The invention provides perfect tissue engineering skin, and the tissue engineering skin can be rapidly constructed in a short time in an operating room (the operation is finished). Meanwhile, the tissue engineering skin comprises the seed cells and dermal matrix, the seed cells are basal layer cells, have the activities of multipotential stem cells and multipotential differentiation functions and are arranged and printed in the corresponding positions according to the anatomical structure of the normal skin, the skin appendage is easily formed, the cure rate is accelerated after the operation, and functions of the skin are restored.

The invention belongs to the technical field of image processing, and particularly relates to an image processing method and device, a terminal and a computer readable storage medium, and the image processing method comprises the steps: obtaining a face image, and detecting a defect region and a normal skin region in the face image; determining a first color vector corresponding to the defect area, a second color vector corresponding to the normal skin area and a difference vector between the second color vector and the first color vector; generating a first mapping table of the face image according to the pixel value of each pixel point in the defect area and the difference vector; carrying out skin color adjustment on the defect area by utilizing a first mapping table to obtain a face image subjected to concealing processing. According to the method and the device, when the concealing-processed face image is subjected to beautifying processing, the problem that the beautifying effectis poor due to the fact that good skin color processing cannot be carried out on flaws such as spots and acne marks is solved, and the beautifying effect on the face image is optimized in the image processing process.

The NSAID, sulindac and / or its metabolites and derivatives, in combination with hydrogen peroxide or another oxidizing agent, such as arsenic trioxide that generates reactive oxygen species (ROS), significantly enhances the killing of cancer cells. This effect occurs at concentrations of each compound that individually have little or no activity directed against cancer cells. A skin cream has been developed and used to treat skin cancer and precancerous skin growths that effectively removes the lesions with no effect on surrounding normal skin.

A composition and a method of producing a composition which simulates hydration, cleansing and other properties of native vernix. The composition contains hydrated synthetic cells in a lipid matrix to provide rheological properties which are substantially similar to those of native vernix, and may also contain proteins. In one embodiment, the composition contains cubosomes / water with up to 30% protein and about 5% lipid to about 30% lipid. The composition may be used to cleanse newborn skin, compromised skin surfaces, as well as normal skin, to provide hydration / barrier function, and other applications.

The invention discloses a medical hand-washing-free skin care disinfectant and a preparation method thereof. The medical hand-washing-free skin care disinfectant comprises, by weight, hydrogen peroxide, tea tree oil, hyaluronic acid, mannitol, stearic acid, glycerin, triethanolamine, kathon, p-hydroxybenzoic acid, medical alcohol, traditional Chinese medicine extract and the like which serve as active components. The disinfectant can rapidly and effectively kill various bacteria and viruses on palms and among fingers, is remarkable in bacteria killing effect, convenient to use and carry, safe and efficient, and is nonpoisonous and non-irritating to the normal skin as the pH (potential of hydrogen) value of the disinfectant is approximate to that of the skin, and people can wash hands with the disinfectant without water and clean two hands at any time and in any places.

The invention discloses a method for preparing a nanofiber membrane with a core / shell wrapping structure through coaxial dual-layer electrostatic spinning and application thereof, and belongs to the field of biomedical composite materials. The method adopts the coaxial dual-layer electrostatic spinning technology for preparing the nanofiber membrane with the core / shell wrapping structure, main components in a skin extracellular matrix are adopted as raw materials, the core is a degradable synthetic macromolecular material carrying type-I collagen, and the shell is a degradable synthesis macromolecular material carrying fibrinogen. The preparation method is simple and easy to implement, and the prepared nanofiber membrane has the good biocompatibility and the biodegradability; along with degradation of the shell layer material in the nanofiber and exposure of the core layer material, component change dynamic bionics in the skin wound repairing process can be achieved, normal skin tissuegeneration is promoted, and the good application prospect is achieved in the aspect of skin wound dressing.

The invention discloses a portable treatment device of electric field coupled with negative pressure for promotion of wound healing. The device comprises a main part, a sandwich-shaped foam dressing, a first biocompatible transparent membrane, anode and cathode patches and a sucker-type drainage tube containing wires; the main part provides negative pressure and direct-current electric field; the sandwich-shaped foam dressing is a negative pressure drainage material for a wound, and meanwhile is used for providing electric field for the wound; the first biocompatible transparent membrane is used for covering the dressing and normal skin around the wound, so that the wound is sealed; the anode and cathode patches are used for being connected with a power supply, and are attached to anode and cathode carbon fiber foam dressings respectively; the sucker-type drainage tube containing the wires has dual effects of drainage and electric conduction, one end of the drainage tube is connected with the foam dressing and the anode and cathode patches, and the other end of the drainage tube is connected with the main part. According to the portable treatment device, negative pressure and direct-current electric field can be applied on the wound synchronously, organic synergy of sealed negative pressure drainage and direct-current electric field technologies for promotion of wound healing is achieved, healing of various acute and chronic wounds is obviously accelerated.

The invention discloses an electric scab excision machine used for deep second degree burn. The electric scab excision machine comprises a machine body; a handle meeting the human engineering is arranged at the back half portion of the machine body; a motor is arranged in the machine body; a main shaft of the motor is connected with a hollow first transmission shaft; the first transmission shaft is connected with a second transmission shaft; the second transmission shaft penetrates the front end of the machine body to enter a sleeve connected with the front end of the machine body; the front end of the second transmission shaft extends out of the sleeve to be connected with a spring jacket type cutter handle; and a cutter is installed on the spring jacket type cutter handle. The electric scab excision machine is connected with an alternating current power source through a transformer; and a switch button is turned on, and the motor in the handle is started to drive the first transmission shaft, the second transmission shaft, a third transmission shaft, the cutter and an impeller to rotate. After the cutter is in contact with the skin, bouncing can be generated in the axial direction and the radial direction, and injuries, caused by overcutting, to the normal skin tissues are avoided. Generated skin cuttings are filtered and absorbed through a dust exhaust apparatus, and the cuttings are prevented from being splashed everywhere.

The invention belongs to the technical field of tissue engineering, and discloses artificial skin and a preparation method thereof. The artificial skin comprises epithelial cells, dermal cells and a biological bracket material. The preparation method comprises the following steps: compounding the dermal cells into the biological bracket material; inoculating the epithelial cells on the surfaces of the dermal cells; carrying out cultivation. As the artificial skin comprises a corium layer, an epidermal layer and active cells, and the epidermal layer comprises cuticle, the artificial skin is similar to normal skin, human skin with complete functions can be regenerated after the transplanting of the artificial skin, and the regenerated skin comprises skin appurtenant organs such as hair and sebaceous glands. Therefore, the artificial skin can be used for treating skin defect caused by inflammation, ulcer, burning and scalding, and also can be used for preparation of skin models used for disease researches, medicine testing and screening, cosmetic testing, or the like.

Whether or not a sample of skin or of a skin equivalent contains such amount of a papillary fibroblast population as to be considered a normal skin is determined by labelling said skin or skin equivalent with at least one antibody specific for papillary fibroblasts and evaluating the extent of such labelling as a marker for skin or skin equivalent quality.

The invention discloses a fat-reducing essential oil. The essential oil is characterized by being composed of following components in percentage by weight: 2 wt% of grapefruit peel oil, 1.6 wt% of pelargonium graveolens oil, 1.2 wt% of cupressus sempervirens oil, 1 wt% of rosemary, 0.8 wt% of pepper seed oil, 0.45 wt% of anise oil, and 91.95 wt% of plant oil. The fat-reducing essential oil and a preparation method thereof have the advantages that: (1) the preparation method has the advantages of simple technology, low cost of production and equipment, easiness in mass industrial production, high efficiency, and no pollution to the environment; (2) the product is non-toxic to humans and animals, and has a prominent fat-reducing effect through a finger massage method; (3) the fat-reducing oil does not contain any chemical synthesis agent such as cuticle stripping agent, and has no incentive to normal skin cells; (4) the effective components in the product are all natural products, are used by people since the beginning of the history, and have far better effects than those of present similar drugs.

The invention comprises a deodorant composition for the treatment of fibers, hair, and / or skin. Preferred embodiments include compositions containing one or more of active ingredients L-arginine, acetylsalicyclic acid, and salicyclic acid adjusted to a pH in the range of 4.0 to 6.0. Preferred compositions include: a carrier, such as water; a moisturizer, such as propylene glycol; one or more of the active ingredients; along with optional preservatives, herbal extract, and skin protectants. Application of a composition for the treatment of odor forming microbes with a pH of about skin does not disrupt normal skin functioning.

The invention discloses a polysaccharide-containing moisturizing and oil-controlling composition and an application thereof in cosmetics. The composition is prepared from the following components in percentage by mass of 0.05 to 20% of polysaccharide moisturizing composition, 0.01%-20% of an oil control composition, 0.5%-20% of an emollient, 0.05%-10% of an emulsion stabilizer, 0.1 to 3.0% of preservative and the balance of auxiliary materials and water. The key technology of the polysaccharide-containing moisturizing and oil controlling composition is that moisturizing and oil controlling areconducted at the same time, the normal skin barrier function is restored, and the polysaccharide moisturizing composition has a good moisturizing effect; the oil control composition efficiently inhibits the activity of 5 alpha-reductase and efficiently inhibits grease and metabolites secreted by sebaceous glands, hair follicles and sweat glands of facial skin, the oil control composition not onlyinhibits the activity of the 5 alpha-reductase, but also shrinks the pore diameter and reduces the channel for grease to be secreted out of epidermis, and the oil control effect is synergistically enhanced through a physical method; and the cosmetic prepared by the invention has relatively low irritation and allergy.

The invention relates to a traditional Chinese medicine, in particular to a Chinese medicinal liquid for treating dermatophytosis, which is prepared from cortex dictamni radicis, pseudolarix, common cnidium fruit, belvedere fruit, lightyellow sophora root, agastache, panax notoginseng, Chinese mugwort leaf and alcohol. The Chinese medicinal liquid has effects of sterilizing, relieving itching and diminishing inflammation, can effectively damage the living environment and the propagating environment condition of the dermatophytosis funguses, kill funguses, eliminate inflammation, recover the normal skin function and completely eliminate dermatophytosis, and has the advantages of quick response, short treatment period, high cure rate and low cost.

The invention provides a vaseline oil gauze producing method. The method includes preparing a medical absorbent gauze, vaseline and paraffin oil as raw materials; placing the vaseline and the paraffin oil in proportion into a stainless steel container or a ceramic container to heat and melt, and stirring evenly; sinking the medical absorbent gauze into the heated, melted, diluted and mixed oil; placing the container accommodating the vaseline oil gauze into a dry heat sterilizer to sterilize. The volume proportion of the vaseline and the paraffin oil is 20:1, and weight proportion of the vaseline and the gauze is 2:1. The vaseline oil gauze produced by the method has the advantages of lubricating, anti-adhesion, anti-oxidation and prompting cell growth and wound healing, can be used for covering surgical wounds and wound surfaces, draining wounds and covering normal skin, and plays a role of moisturizing and caring skin, anti-aging for skin cells and the like.