47 results about "Daucosterol" patented technology

The invention relates to a new application of daucosterol in medicine and health care product preparation, in particular to application of daucosterol in preparing medicines and health care products for promoting proliferation of neural stem cells. The daucosterol is a phytosterol derivative and is sitosterol-3-O-glucoside which widely exists in plants, and the processes of extracting, separation and content detection are simple and convenient. According to research, the medicines can promote proliferation of osteoblastlike cells, protect endothelial cells of human capillaries and further can reduce blood sugar activity. By means of the application, primarily-cultured neural stem cells and aged mice serve as the materials, and users can observe the effect of daucosterol on the neutral stem cells. In-vitro experiments and integral experiments prove that the daucosterol has the effect of promoting proliferation of the neutral stem cells. In the in-vitro experiments, the daucosterol with the dose ranging from 10 mu mol / L to 100 mu mol / L can promote proliferation of the neutral stem cells, and in the integral experiments, the daucosterol with the dose of 10mg / kg can promote proliferation of the neutral stem cells of the aged mice.

The invention discloses a method for separating and purifying 5-hydroxy-7, 3', 4'-triethoxy flavone, beta-sitosterol or / and betal-daucosterol from fine felt hairy honeysuckle. According to the method for separating and purifying 5-hydroxy-7, 3', 4'-triethoxy flavone, beta-sitosterol or / and betal-daucosterol from fine felt hairy honeysuckle, disclosed by the invention, the purity of each obtained compound is high, the new use value of fine felt hairy honeysuckle is developed, and the definition of pharmacodynamic material of fine felt hairy honeysuckle is favorable.

The invention discloses an anticancer synergistic composition. Active components of the anticancer synergistic composition comprise daucosterol and cyclophosphamide, and preferably, a weight ratio of daucosterol to cyclophosphamide is 10-50: 1. The daucosterol and cyclophosphamide can produce synergistic cancer-resistant effects. Daucosterol is natural extract and has very small toxicity, small side effects and a low adverse reaction rate. The use amount of cyclophosphamide in the anticancer synergistic composition is only 1 / 2 of the conventional use amount and thus a cost, side effects and an adverse reaction rate are low.

The invention relates to external antineoplastic Livistona extract with chemical constituents as diosgenin, beta- sitosterol, sterone, beta- daucosterol, and ceryl alcohol. Wherein, smashing collected fresh root, seed and leaves of Livistona plant; using ethanol to dip and filter out solid and liquid phases; distilling to recycle ethanol and obtain black extractive A; filtering the separated solid, extracting in water, condensing; mixing the extractive and condensed liquid; extracting with acetic acid ethyl ester and petroleum ether respectively; recrystalllizing with silica gel column to obtain monomer compound. The pharmacological experiments show that the product has inhibition to seven tumor cell strains.

The invention provides a mite-killing water emulsion, which is prepared by using daucosterol as main raw material and adding a solvent, a solubilizer, an emulsifier and other auxiliary materials to the daucosterol. The mite-killing water emulsion is an environment-friendly acceptable pesticide, which is safe to animals and human beings, and has a profound significance for the long-term development of the ecological environment, the health of the human beings and the comprehensive treatment of the diseases. Compared with the traditional pesticide, the mite-killing water emulsion has the following characteristics and advantages: 1, the daucosterol is abundant in nature, the content is higher especially in plants, the toxicity of the daucosterol is low, and the daucosterol is easily degradable and is safe for the ecological environment; 2, the extracting method of the daucosterol is simpler, and the daucosterol can be extracted by techniques of a liquid phase chromatographic separation method and the like; 3, the daucosterol also can be synthesized artificially, has low cost, is easily used for industrial large-scale production; 4, due to physical and chemical properties, the daucosterol can be dissolved in a plurality of solvents, is easily blended with other mite-killing components for preparing pesticide, and can play a role in improving mite-killing effect; and 5, with soybean oil as solvent, the daucosterol plant miticide water emulsion provided by the invention is non-toxic and environment friendly, can be used for increasing the solubility of the daucosterol in the water and also plays a role in promoting the effect that the pesticide permeates into the plant skin.