53 results about "PL Extract" patented technology

Disclosed are compositions and corresponding methods of their use that include extracts from Loropetalum chinensis, Camptotheca acuminate, Lonicera maackii, Washingtonia filifera, Artemisia parviflora, Glochidion lanceolaris, Polygonum hydropiper, Populus davidiana, Tsoongiodendron odorum, Trema angustifolia, Ficus tikoua, Pistacia chinensis, Zizyphus mauritiana, Garuga forrestii, Michelia figo, Sabina chinensis, Cuphea balsamona, Setaria palmifolia, Polygonum lapathifolium, Machilus longipedicellata, Geranium nepalense, Ipomoea obscura, Cedrus deodara, Quercus aliena, Carqueja, Condurango, Catuaba, Carex baccans, Chrysalidocarpus lutescens, Gnaphalium pensylvanicum, Celtis sinensis, Cassia siamea, Catalpa yunnanesis, Potamogenton perforliatus, Cinnamomum japonicum, or any combination thereof.

The invention relates to a burdock fruit extract, its preparing process and use thereof, wherein the extract comprises 51-80 wt% of total lignanoids compound with burdock aglycone as the main ingredient and burdock glycosides, and 20-49 wt% of other constituents.

The invention provides a preparation method of arctium fruit extract for decreasing blood sugar, wherein the extract comprises Arctiin, Matairesinol, Lappaol A, Lappaol C, Lappaol Fú¼LappaolHú¼Arctignan Eú¼beta-sitosterol and daucosterol.

The present invention provides a method of efficiently and stably producing LCPUFA-PL. Specifically, the invention provides a method for producing phospholipids that contain LCPUFA as a constituent (LCPUFA-PL), wherein lipid producing cells producing lipids that contain long-chain polyunsaturated fatty acids (LCPUFA) are used as a starting material, the method including a PL extracting step of extracting phospholipids (PL) from defatted cells obtained by extracting triglyceride (TG)-containing oil or fat from the lipid producing cells.

The invention discloses a method for preparing a PL (platelet lysate) and an application of the PL. The method for preparing the PL comprises the following steps: concentrated platelets are centrifuged under a centrifuge at 800-1000 rpm for 15-25 min, the upper layer is platelet-rich plasma and the bottom layer is a red blood cell layer after centrifugation, and the red blood cell layer at the bottom is separated out; the upper platelet-rich plasma is mixed thoroughly in batches, and platelets are sufficiently lysed with a multigelation process; cell debris is removed, and the final PL is obtained. The invention also provides a cell culture method for culturing cells with the prepared PL. With adoption of the method, the yield of PL extracted from the concentrated platelets can be increased to 95%, operation time is shortened, and clinical expired products can be repeatedly used and developed.

The present invention provides a method of efficiently and stably producing LCPUFA-PL. Specifically, the invention provides a method for producing phospholipids that contain LCPUFA as a constituent (LCPUFA-PL), wherein lipid producing cells producing lipids that contain long-chain polyunsaturated fatty acids (LCPUFA) are used as a starting material, the method including a PL extracting step of extracting phospholipids (PL) from defatted cells obtained by extracting triglyceride (TG)-containing oil or fat from the lipid producing cells.

A method of treating neurological condition in a subject by administration of an extract, or fraction or sub-fraction thereof, of Nerium species or Thevetia species is provided, wherein the extract, or fraction or sub-fraction thereof, excludes oleandrin and neriifolin. Alzheimer's disease, Huntington's disease or stroke are treated by administering a therapeutically effective amount of the extract, or a fraction or sub-fraction thereof, to a subject. The extract can be present in a pharmaceutical composition.

The invention discloses an application of radix acanthopanacis trifoliate extract in inhibiting alpha-glucosidase. The radix acanthopanacis trifoliate extract is extracted and concentrated by ethanol and then extracted respectively by petroleum ether, ethylacetate and normal butanol. The radix acanthopanacis trifoliate extract is identified to have 9 terpenoids. The invention also discloses an alpha-glucosidase inhibitor, and the alpha-glucosidase inhibitor comprises radix acanthopanacis trifoliate extract as well as one or more additives acceptable on the medicine. The experiment shows that the extract of radix acanthopanacis trifoliate leaves, stalks and roots has inhibitory activity for the alpha-glucosidase; in 9 terpenoids of the radix acanthopanacis trifoliate extract, the compound 6 has best activity for inhibiting the alpha-glucosidase, which is far higher than a reference product acarbose.

The invention relates to an ophiopogon japonicus extract, a preparation method and the hypoglycemic application thereof. The preparation method of the ophiopogon japonicus extract comprises: ophiopogon medicine is taken to be decocted for 1-3 times, added with water by 5-20 times every time, then decocted for 30-120min every time, and filtered and merged into water-decocted liquid; after being concentrated to the density of 1.05-1.35g / ml, the obtained water-decocted liquid is added with ethanol until the alcohol content has the volume percent of 50-80%, and is collected and precipitated after staying over night; the precipitation is separated and purified by sephadex column, and then processed by vacuum freeze drying, so that white loose flocculent crystal which is the ophiopogon japonicus extract can be obtained, and the extract has the sugar content of 90-98%( based on fructose) as well as the molecular weight within the range of 500-2000. Animal experiments prove that the ophiopogon japonicus extract has remarkable hyperglycemic effect, and the action mechanism of the ophiopogon japonicus extract can be further explained by vitro experiments; the result shows the ophiopogon japonicus extract can reduce blood sugar levels by inhibiting the activity of alpha-glucosaccharase in alimentary canal, reduce the absorption for glucose by intestinal villi and the protective action for islet cells. Therefore, the extract can be used for developing medicine for treating type II diabetes.

The present invention provides a method of efficiently and stably producing LCPUFA-PL. Specifically, the invention provides a method for producing phospholipids that contain LCPUFA as a constituent (LCPUFA-PL), wherein lipid producing cells producing lipids that contain long-chain polyunsaturated fatty acids (LCPUFA) are used as a starting material, the method including a PL extracting step of extracting phospholipids (PL) from defatted cells obtained by extracting triglyceride (TG)-containing oil or fat from the lipid producing cells.

The invention relates to Geranium strictipes effective part preparation and medical use of the Geranium strictipes for preventing and curing colonitis. The extract of the Geranium strictipes effective part provided by the invention is refined from Yi nationality's medicine Geshanxiao through macroreticular resin. Geshanxiao is dried roots of geranium strictipes R. Knuth which belongs to geraniaceae geranium wilfordii. According to the invention, a rat acetic acid caused ulcerative colitis model is adopted for observing influences on relevant biochemical criterions of common clinical symptoms, pathomorphology and oxidative damage by the Geranium strictipes effective part. As shown in the experimental results, the Geranium strictipes effective part has certain therapeutical effect on the acetic acid caused ulcerative colitis rat model, and can ameliorate clinical symptoms thereof. Therefore, the Geranium strictipes effective part can be expected and applied in preparation of drugs capable of preventing and curing the ulcerative colitis.

The invention discloses a trichosanthes bark and allium macrostemon extract and a preparation method thereof. The composition is prepared by adopting the following steps: mixing trichosanthes bark with allium macrostemon in the weight proportion of 2:1 to 1:1; adding water or C1-3 ethanol with the concentration less than 50 percent for extraction; extracting an extracted solution by ion exchange resin and macroporous absorbent resin; extracting 50 to 90 weight portions of components from trichosanthes bark and the ion exchange resin of allium macrostemon; extracting 10 to 50 weight portions of components from the trichosanthes bark and macroporous resin of the allium macrostemon; mixing the two components; and obtaining the extract. The extract is applied to preparing medicines for treating diseases of cardiovascular system, and has determined curative efficacy; moreover, the extract reaches the goal of reducing dose without reducing medicine efficacy and has an extensive application prospect.

The invention provides a composition of a drug extract for eliminating face acne marks and a preparation method of the composition. The drug composition having the effect for eliminating the face acne marks. The composition is prepared from the following raw materials: root of polygala fallax, herb of nervilia fordii, herb of euphorbia hirta, barke of cassia siamea, herb of salvia plebeia, herb of origanum vulgare, herb of lycopodium clavatum, herb of pothos chinensis, leaf of tetracera scandens and radix aconiti carmichaeli, wherein the weight percent of any component of the root of polygala fallax, herb of nervilia fordii, herb of euphorbia hirta, herb of cassia siamea, herb of salvia plebeian, herb of origanum vulgare, herb of lycopodium clavatum, herb of pothos chinensis, leaf of tetracera scandens and radix aconiti carmichaeli is not greater than 10 percent of the total weight. The composition has a remarkable effect for eliminating the face acne marks, and is definite and safe in efficacy and free from irritation and sensitization to the skin.

The invention relates to a paeonia suffruticosa peel flavonoid extraction process and extracts thereof. The extraction process of paeonia suffruticosa 'Feng Dan' peel flavonoids is optimized with theyield of paeonia suffruticosa 'Feng Dan' peel flavonoids as the index, the influence of the four factors of ethanol volume fraction, liquid-material ratio, extraction temperature and ultrasonic poweron the yield of peel flavonoids is investigated, and the optimal extraction process parameters for paeonia suffruticosa 'Feng Dan' peel flavonoids are determined by analyzing the test result. An in-vitro anti-oxidation test on the flavonoid extracts in paeonia suffruticosa 'Feng Dan' peel shows that the flavonoid extracts in paeonia suffruticosa 'Feng Dan' peel have a scavenging effect on ABTS andDPPH within a concentration range selected in the test, the phenomenon of great waste of paeonia suffruticosa peel at present is avoided, and the paeonia suffruticosa peel resource is better developed and utilized.

The invention discloses an additive composition containing lysozyme and a plant extract. The additive composition consists of lysozyme and the plant extract. The plant extract is one or more of a centella asiatica extract, a giant knotweed rhizome extract, a scutellaria baicalensis root extract, a tea extract, a glycyrrhiza glabra root extract, a chamomilla recutita flower extract and a rosemary leaf extract. The lysozyme is used in combination with one or more of the plant extracts, so that on one hand, the problem is solved that oral care products which frequently use chemical components easily cause ecological imbalance of oral bacteria, make the bacteria generate drug resistance and cannot achieve the effect of preventing oral diseases; on the other hand, the defect of weak bactericidal ability of the lysozyme to gram-negative bacteria is overcome, meanwhile the defect of weak bacteriostatic effect of single plant extracts is overcome, and accordingly the additive composition containing the lysozyme and the plant extract has a good broad-spectrum bacteriostatic effect.

Terminalia ferdinandiana (T. ferdinandiana) leaf extract can be provided in a composition for use in inhibiting bacterial growth. The extract or composition can be in or as a personal hygiene producte.g. a deodorant or anti-perspirant, a cosmetic, a cosmeceutical, a surface treatment product or a preservative, and can include T. ferdinandiana fruit extract. The leaf extract can be a methanolic extract, alcoholic extract, steam extract, aqueous extract; ethyl acetate extract; chloroform extract; or hexane extract, and can include a tannin e.g. chebulic acid, corilagen, chebulinic acid or chebulagic acid and / or at least one flavone e.g. luteolin. The composition can be provided as a topical skin application.

The invention relates to an Ovateleaf Holly Bark extract product having a hepatic injury prevention effect, and an application thereof. Ovateleaf Holly Bark is dried bark or velamen of an Aquifoliaceae plant Ilex roundda Thunb.. The active extract product is prepared on the basis of researches of the traditional efficacies of Ovateleaf Holly Bark. The Ovateleaf Holly Bark extract product can substantially reduce the activity of ALT and AST in the serum of CCl4 / alcohol caused hepatic injury model mice and the content of MDA in hepatic tissues of the mice, and enhances the SOD activity of livers, so the active extract has an obvious hepatic protection effect on chemical hepatic injuries and alcoholic hepatic injuries.

The invention relates to a pharmaceutical composition for treating diabetes, wherein the constituents of the composition comprises (by weight ratio): giant knotweed rhizome extract 48-57%, mulberry leaf extract 18-25% and atrichum extract 22-33%.

The invention discloses jujube flower extract and an antibacterial application thereof. The extract is obtained in the following steps: crushing the jujube flowers, soaking the crushed jujube flowersfor twice by using an ethanol aqueous solution with the volume concentration of 90 percent according to a material-liquid ratio of 1:2 to 1:4, wherein the soaking time for each time is 24 to 72 hours;decompressing concentrating the soaking solution at the temperature of 30 to 50 DEG C, and obtaining extract; and extracting the extract by using ethyl acetate and water in a dispersion manner, and decompressing concentrating an ethyl acetate phase at 25 to 40 DEG C, and obtaining the jujube flower extract. By virtue of the activity screening of the jujube flower extract as well as a monomer compound for the seven selected bacteria (grampositive staphylococcus aureus ATCC 43300, staphylococcus aureus ATCC 33591, staphylococcus aureus ATCC 29213, staphylococcus aureus ATCC 25923, enterococcusfaecalis ATCC 51299, enterococcus faecium ATCC 35667 and escherichia coli ATCC 25922), the jujube flower extract has good antibacterial activity, and can be used as an antibacterial agent.

An extract of Polygonum multiflorum Thunb. ex Murray var. hypoleucum (Ohwi) or of Polygonum hypoleucum (Ohwi) for improving metabolic syndrome is prepared by the following method: (a) providing fresh or dry Polygonum multiflorum Thunb. ex Murray var. hypoleucum (Ohwi) or Polygonum hypoleucum (Ohwi) in partial or whole plant ; (b) extracting the partial or whole plant by a solvent to obtain a crude extract; (c) condensing and drying the crude extract to obtain an extract product; and (d) collecting the extract product. The present invention also relates to a pharmaceutical and a food composition having the above extract for improving the metabolic syndromes. The extract of the present invention can be easily prepared and is demonstrated to modulate the levels of both blood glucose and blood lipid, to inhibit the activities of glycolytic enzymes and acetyl-CoA carboxylase, and to stimulate acyl-CoA oxidase. The extract of the present invention is capable of improving metabolic syndromes.

The invention discloses a skin care composition for unhairing of iris germanica. The skin care composition is prepared from in parts by weight: 0.1 to 10 parts of iris germanica root extract and 0.1 to 10 parts of hydrangea serrata leaf extract. According to the composition disclosed by the invention, injury due to unhairing to the skin can be reduced by compounding the iris germanica root extractwith the hydrangea serrata leaf extract.

The invnetion discloses application of radix angelicae sinensis as a unique active component to preparation of drug for relieving fever. The drug for relieving fever is obtained by taking the radix angelicae sinensis or a radix angelicae sinensis extract as the unique active component and adding acceptable auxiliary additive component. The radix angelicae sinensis extract can be an extract of theradix angelicae sinensis extracted with 0 to 100% ethanol solution or radix angelicae sinensis volatile oil, the mass content of ferulic acid in an ethanol extract is larger or equal to 1%, the mass content of ligustilide in the ethanol extract is larger than or equal to 30%, the mass content of ligustilide in the radix angelicae sinensis volatile oil is larger than or equal to 30%. the application of the radix angelicae sinensis as the unique active component to preparation of drug for relieving fever takes the radix angelicae sinensis or the radix angelicae sinensis extract as the unique active component, the prepared drug is applied to prevention and control of fever, achieves significant curative effects, for example, when the effective drug component is within a certain range, the effect of relieving the fever of the effective drug component is superior to that of aspirin and a ligustilide monomer.

A herbal extract composition from Lythraceae and Lauraceae family plants and its usage as insulin resistance reducer, syndrome X normalization, pre-diabetes and type 2 diabetes treatments, particularly as activator in insulin signal pathway, as modulator in glucose transport system, as modulator in adiponectin secretion, and as suppressor in insulin resistance. Representative from Lythraceae family has been selected Lagerstroemia speciosa, and representative from Lauraceae family has been selected Cinnamomum burmannii. Such herbal extract composition work synergistically to strengthen pharmacological effect produced by each extract if they act alone.

The invention relates to a preparation of a compound extract of anemarrhena, astragalus and bitter gourd and use thereof. The weight ratio of the anemarrhena to astragalus to bitter gourd is 2-4:1-2:1; and the three types of Chinese medicaments are mixed and then processed into an extract or the three types of Chinese medicaments are processed into an extract respectively and then mixed to obtain the extract, and the extract can be made into oral liquid, tablets, capsules or injections. The compound extract of anemarrhena, astragalus and bitter gourd possesses an activity of inhibiting the alpha-glucosidase, and can be used for reducing postprandial glycemia, preventing and treating diabetes and complications of diabetes, and the like.

An extract of Polygonum multiflorum Thunb. ex Murray var. hypoleucum (Ohwi) or of Polygonum hypoleucum (Ohwi) for improving metabolic syndrome is prepared by the following method: (a) providing fresh or dry Polygonum multiflorum Thunb. ex Murray var. hypoleucum (Ohwi) or Polygonum hypoleucum (Ohwi) in partial or whole plant ; (b) extracting the partial or whole plant by a solvent to obtain a crude extract; (c) condensing and drying the crude extract to obtain an extract product; and (d) collecting the extract product. The present invention also relates to a pharmaceutical and a food composition having the above extract for improving the metabolic syndromes. The extract of the present invention can be easily prepared and is demonstrated to modulate the levels of both blood glucose and blood lipid, to inhibit the activities of glycolytic enzymes and acetyl-CoA carboxylase, and to stimulate acyl-CoA oxidase. The extract of the present invention is capable of improving metabolic syndromes.

Disclosed is a red sage root and dalbergia wood extract, which is prepared from cyclodextrin inclusion compound of water saturation distillate of red sage root and dalbergia wood, and the water-soluble portions of red sage root and dalbergia wood. The extract can be used for preparing injections of various combinations of the raw materials with controllable process, stabilized quality, better repeatability, and improved effect.

The invention provide a sanguisorba extract for treatment of AIDS (acquired immunodeficiency syndrome) and a preparation method thereof, and the sanguisorba extract mainly comprises gallic acid, ellagic acid, hydrolysable tannin and condensed tannin. The sanguisorba extract has excellent inhibitory activity and low cytotoxicity to R5-tropic and X4-tropic AIDS viruses.

The invention relates to Geranium strictipes effective part preparation and medical use of the Geranium strictipes for preventing and curing colonitis. The extract of the Geranium strictipes effective part provided by the invention is refined from Yi nationality's medicine Geshanxiao through macroreticular resin. Geshanxiao is dried roots of geranium strictipes R. Knuth which belongs to geraniaceae geranium wilfordii. According to the invention, a rat acetic acid caused ulcerative colitis model is adopted for observing influences on relevant biochemical criterions of common clinical symptoms, pathomorphology and oxidative damage by the Geranium strictipes effective part. As shown in the experimental results, the Geranium strictipes effective part has certain therapeutical effect on the acetic acid caused ulcerative colitis rat model, and can ameliorate clinical symptoms thereof. Therefore, the Geranium strictipes effective part can be expected and applied in preparation of drugs capable of preventing and curing the ulcerative colitis.

The disclosure concerns an extract of Acanthopanax koreanum and its use. More particularly, it concerns the extract of Acanthopanax koreanum comprising 1) the extract of Acanthopanax koreanum extracted from water, 2) among the water extract, the extract of Acanthopanax koreanum only containing ethanol insoluble part obtained by precipitating ethanol, 3) among the ethanol insoluble part, the extract of Acanthopanax koreanum containing polysaccaride with a molecular weight larger than range of 12,000˜14,000, or 4) among the ethanol insoluble part, the extract of Acanthopanax koreanum containing polysaccaride with a molecular weight larger than 100,000, which is respectively obtained from the root or stem of Acanthopanax koreanum. The extract of the present invention shows a high inhibitory activity against hepatitis and protects the liver, and thus, can be used for the treatment or prevention of hepatitis, or as a liver protective drug.