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41results about How to "Reduce MDA content" patented technology

Application of active peptide in preparation of medicine for preventing and treating ALD

ActiveCN119638789Adamage reliefInhibiting the increase in alanine aminotransferase activityPeptide/protein ingredientsDigestive systemDiseasePharmaceutical Substances
The invention provides an application of an active peptide in preparation of a medicine for preventing and treating ALD (Atomic Lymphosis Disease). The amino acid sequence of the active peptide is shown as SEQ ID NO: 1, the active peptide can effectively relieve damage of ethyl alcohol to liver cells, increase of glutamic-pyruvic transaminase activity, lactic dehydrogenase activity and malondialdehyde content and decrease of glutathione content caused by ethyl alcohol can be remarkably inhibited, then the preventing and treating effect on ALD is achieved, and the active peptide is suitable for preparing drugs for preventing and treating ALD and has a good application prospect. Meanwhile, an active peptide resource library with ALD prevention and treatment effects is also enriched.
Owner:GUANGDONG OCEAN UNIVERSITY

Application of burdock root polysaccharide in preparation of medicine for treating cognitive impairment

The invention discloses application of burdock root polysaccharide in preparation of a medicine for treating cognitive impairment, and belongs to the technical field of traditional Chinese medicines. Experiments prove that the burdock root polysaccharide can improve cognitive impairment and autonomous exploration ability of D-galactose induced cognitive impairment model mice, increase the activity of superoxide dismutase in serum of the mice, reduce the content of malondialdehyde, reduce the content of hippocampus interleukin-1beta and tumor necrosis factor-alpha in brains of the mice, and improve the cognitive impairment activity of the mice. According to the present invention, with the composition, the loss of the neuron in the hippocampal region of the cognitive impairment model mouse can be reduced so as to achieve the neuron protection effect, such that the good treatment effect on the cognitive impairment can be provided, and the new approach is provided for the development of the cognitive impairment-related drug.
Owner:DALIAN MEDICAL UNIVERSITY

Composite plant stress-resistant agent as well as preparation method and application thereof

The invention discloses a compound plant stress-resistant agent as well as a preparation method and application thereof. The compound plant stress-resistant agent comprises a compound of glycine betaine and polyglutamic acid, wherein the mass ratio of the glycine betaine to the polyglutamic acid is 1: (0.1-2). The preparation method of the composite plant stress-resistant agent comprises the following steps: mixing polyglutamic acid or a solution thereof with glycine betaine in ethanol to obtain a mixed solution, adjusting the pH value of the mixed solution to 3.0-6.0, carrying out an ultrasonic reaction to obtain a reaction solution, adding absolute ethyl alcohol into the reaction solution, stirring, filtering, and drying the precipitate to obtain the composite plant stress-resistant agent. The compound plant stress-resistant agent can be applied to crops in a foliage spraying or root irrigation mode, the growth conditions of grain crops such as corn, peanuts, celery and grapes and / or economic crops under adversity stress such as drought, low temperature and high salt are remarkably relieved, and the crop yield is increased.
Owner:NANJING TECH UNIV

Bacillus velezensis with saline-alkaline tolerance and growth promoting functions, bio-organic fertilizer and application of bio-organic fertilizer

The invention discloses bacillus velezensis with saline-alkaline tolerance and growth promotion functions, a bio-organic fertilizer and application of the bio-organic fertilizer, and relates to the technical field of agricultural microorganisms. The bacillus velezensis is preserved in the Guangdong Microbial Culture Collection Center on November 6, 2024, the preservation address is the 5th floor of the building 59, No.100 Courtyard, Xianlie Middle Road, Guangzhou, and the preservation number is GDMCC (China General Microbiological Culture Collection Center): 65428. The strain has strong saline-alkaline tolerance, can effectively survive in moderate and severe saline-alkaline environments, remarkably improves the germination rate of crops and the content of soluble sugar, proline and antioxidant enzyme, and reduces the content of malondialdehyde. The bio-organic fertilizer produced by using the strain can effectively improve crop yield and soil organic carbon, reduce pH and total salt content, and has a remarkable improvement effect on saline-alkali soil.
Owner:INST OF SOIL FERTILIZER & WATER SAVING AGRI GANSU ACAD OF AGRI SCI

Application of vitis amurensis VaWRKY72 gene in cold resistance of plants

The invention belongs to the technical field of molecular biology and genetic engineering, and particularly relates to application of a vitis amurensis VaWRKY72 gene in improving cold resistance of plants. According to the invention, the cold-resistant effect of the over-expressed vitis amurensis VaWRKY72 gene in regulation and control of arabidopsis thaliana and grape is found for the first time. Through overexpression of the vitis amurensis VaWRKY72 gene in arabidopsis thaliana and grape, it is found that the vitis amurensis VaWRKY72 gene can be used for improving the cold stress resistance by reducing the malondialdehyde content, reducing the electrolyte permeability, improving the proline content and the activity of peroxidase, catalase and superoxide dismutase, eliminating excessive ROS and promoting the expression of cold stress related genes. Therefore, the tolerance of the plant to low-temperature stress is improved.
Owner:NINGXIA UNIVERSITY

Saline-alkali tolerant bacteria strain and application thereof

The invention discloses a saline-alkaline tolerant bacterium strain and application thereof. The saline-alkaline tolerant bacteria strain is selected from any one or more of the following bacteria: Pseudoclavibacter sp., the preservation number of which is CGMCC No.32646, the preservation number of which is CGMCC No.32646, the preservation number of which is CGMCC No.32646, and the preservation number of which is CGMCC No.32646. The preservation number of the providencia sp. Is CGMCC (China General Microbiological Culture Collection Center) No.32647, and the preservation number of the providencia sp. Is CGMCC No.32647. The preservation number of the planococcus sp. Is CGMCC No.32648, the planococcus sp. Is preserved in the China General Microbiological Culture Collection Center (CGMCC) on November 15, 2024, and the preservation address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing, China. The bacillus amyloliquefaciens and the bacillus amyloliquefaciens have the capabilities of fixing nitrogen The saline-alkaline tolerant growth of plants can be obviously promoted, the content of chlorophyll and proline in rice is increased, the activity of antioxidant enzyme is improved, and the content of malondialdehyde is reduced; in addition, the providencia has nitrogen fixation capacity, the pseudoochrobactrum pseudococcum has iron production capacity, and the motility coccus has iron production and phosphorus solubilizing capacity.
Owner:YANGZHOU UNIV

Application of gamma-aminobutyric acid in relieving saline-alkali stress of cotton and method for relieving saline-alkali stress of cotton

PendingCN119423083AReduce MDA contentEnhance catalase activityBiocidePlant growth regulatorsBiotechnologyDismutase
The invention belongs to the technical field of crop cultivation, and particularly relates to application of gamma-aminobutyric acid in relieving saline-alkali stress of cotton and a method for relieving the saline-alkali stress of the cotton. According to the method, gamma-aminobutyric acid is used as an exogenous additive, and when the cotton is stressed by a secondary salt solution with the salt content of 0.45%-0.47% and the pH value of 7.5-8.0, the gamma-aminobutyric acid is added into the secondary salt solution; gamma-aminobutyric acid relieves secondary salt solution stress by improving superoxide dismutase activity of cotton, improving peroxidase activity of cotton, reducing malondialdehyde content of cotton, improving catalase activity of cotton, reducing superoxide anion content, reducing H2O2 content of cotton and improving soluble protein content of cotton; compared with other plant growth regulators, the gamma-aminobutyric acid has higher cotton saline-alkali stress relieving activity. And the gamma-aminobutyric acid is an amino acid naturally existing in an organism, has no toxicity to a human body, has no residual toxicity and residual effect after being used for treating cotton, and has practical utilization value.
Owner:ECONOMIC CROPS RES INST XINJIANG ACAD OF AGRI SCI (XINJIANG UYGUR AUTONOMOUS REGION COTTON RES INST XINJIANG UYGUR AUTONOMOUS REGION SUGAR BEET IMPROVEMENT CENT)

Dendrobium loddigesii polysaccharide extract as well as preparation method and application thereof

The invention discloses a preparation method of a dendrobium loddigesii polysaccharide extract, which comprises the following steps: crushing cleaned dendrobium loddigesii into dendrobium loddigesii powder, extracting with ethanol, filtering, and drying to obtain dendrobium loddigesii powder to be extracted; mixing p-toluenesulfonic acid, n-butyl alcohol and water to obtain an extraction solution; adding to-be-extracted dendrobium loddigesii powder into the extracting solution, heating and extracting, separating, dialyzing to obtain a crude extracting solution, carrying out alcohol precipitation, dialyzing the precipitate, and freeze-drying to obtain the dendrobium loddigesii polysaccharide extract. The mixed solution is used for extracting the dendrobium loddigesii polysaccharide, extraction and separation of the dendrobium loddigesii polysaccharide extract can be achieved, deproteinization treatment is not needed, the purity of the obtained dendrobium loddigesii polysaccharide extract can reach 90% or above, the process is simple and convenient, reproducibility is good, cost is low, and large-scale production is easy. The invention further discloses application of the dendrobium loddigesii polysaccharide extract prepared by the preparation method and the pharmaceutical composition of the dendrobium loddigesii polysaccharide extract in preparation of drugs or health care products for preventing or treating liver injury.
Owner:ZHEJIANG UNIV

Liquid preservative for fresh walnut kernel

This invention relates to the field of food preservation technology and discloses a liquid preservative for preserving fresh walnut kernels. The preservative comprises a natural preservative, a solubilizing and stabilizing agent, and a solvent. This liquid preservative uses natural phloretin as the preservative component, combined with Tween 80 as a solubilizing and stabilizing agent and ethanol as a solvent. This effectively solves the problems of poor water and oil solubility and inadequate stability of phloretin, allowing it to be stably dispersed in the preservative system and fully exert its antioxidant and antimicrobial effects. Furthermore, the preparation method is simple and easy to implement, and the production process is safe and controllable. It is convenient to use; the preservation of fresh walnut kernels can be achieved through dilution and soaking. The diluted solution can be reused, reducing usage costs. Simultaneously, it can inhibit bacterial growth during the storage of fresh walnut kernels, delay oxidative deterioration, maintain their good appearance and quality, extend shelf life, and meet the market demand for high-quality fresh walnut kernels.
Owner:LINCANG GONGTOU SHUNNING NUT DEV CO LTD

Application of Bacillus pumilus AD14 in improving saline-alkali soil and enhancing soybean resistance to saline-alkali stress

The invention discloses an application of Bacillus pumilus AD14 in improving saline-alkali soil and improving the resistance of soybean to saline-alkali stress, which belongs to the technical field of agricultural microorganisms. In order to screen Bacillus pumilus that can improve saline-alkali soil and significantly improve the resistance of soybean to saline-alkali stress, the invention screens a strain AD14 with good salt-alkali resistance from saline-alkali soil. The strain is identified as Bacillus pumilus ( Bacillus pumilus ), the experiment found that the strain has the growth-promoting properties of dissolving phosphorus, fixing nitrogen and producing pectinase; it can change the physical and chemical properties of saline-alkali soil, increase the activities of urease, sucrase and catalase in saline-alkali soil; improve the stress resistance of soybean in saline-alkali soil and promote the growth of soybean in saline-alkali soil. Therefore, Bacillus pumilus AD14 has broad application prospects in improving saline-alkali soil, improving the resistance of soybean to saline-alkali stress and promoting the growth and development of soybean under saline-alkali stress.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Astaxanthin-loaded fucoidan-phycocyanin nanoparticles, composite preservative film prepared therefrom, and preparation method and application thereof

This invention discloses fucoidan-phycocyanin nanoparticles loaded with astaxanthin. The nanoparticles are formed by the self-assembly of fucoidan and phycocyanin through electrostatic interactions and hydrogen bonds to form a carrier, encapsulating astaxanthin within. The nanoparticles have a particle size of 250 nm–350 nm, an absolute zeta potential ≥20 mV, a polydispersity index ≤0.30, and an astaxanthin encapsulation efficiency ≥78%. The composite preservation film uses carboxymethyl cellulose as the film-forming matrix, with the nanoparticles uniformly dispersed therein. The water contact angle is ≥90°, and the water vapor transmission rate is ≤14%. g·mm / (m²·h·kPa), ABTS free radical scavenging rate ≥80%; This invention significantly improves the water solubility and stability of astaxanthin through the ternary synergy of polysaccharide-protein-active factors, realizing the integration of multiple functions of anti-oxidation, antibacterial and physical barrier. When applied to grapes for room temperature preservation for 10 days, the weight loss rate is only 20.23%, and the hardness is maintained at 7.87N. The preservation effect is significantly better than commercially available PE film and pure carboxymethyl cellulose film. Moreover, the composite film has good biodegradability and has broad application prospects in the field of food preservation.
Owner:JIANGSU OCEAN UNIV

Cassava transcription factor meWRKY30 and application thereof

PendingCN122278929AImprove cold resistanceImprove resistance to low temperature stressBiotechnologyPlant hormone
This invention belongs to the field of biotechnology, specifically relating to the cassava transcription factor MeWRKY30 and its applications. This invention cloned the transcription factor gene of MeWRKY30 from cassava. Overexpression of this gene in cassava can improve the resistance of transgenic cassava plants to low-temperature and drought stress. The effects of qRT-PCR on cassava... MeWRKY30 Gene expression was significantly upregulated after drought and treatment with the plant hormone abscisic acid (ABA). After recovery from low temperature treatment, the malondialdehyde content of the overexpressing cassava lines decreased, wilting was reduced, root growth inhibition was lessened, and the number of cortical cells in the root tip meristem was significantly increased.
Owner:SANYA RES INST OF CHINESE ACAD OF TROPICAL AGRI +1

Salt-tolerant bacterial strain and application thereof

ActiveCN119530082BHas the ability to fix nitrogenAbility to produce iron
The application discloses a salt and alkali tolerant bacterial strain and application thereof. The salt and alkali tolerant bacterial strain is selected from any one or more of the following: Pseudoclavibacter sp. with a preservation number of CGMCC No. 32646, Providencia sp. with a preservation number of CGMCC No. 32647, and Planococcus sp. with a preservation number of CGMCC No. 32648, which are all preserved in the China General Microbiological Culture Collection Center (CGMCC) on November 15, 2024, and the preservation address is No. 1, Xibanchenli, Chaoyang District, Beijing, China. All of them have the abilities of nitrogen fixation and indole acetic acid production; can significantly promote the growth of plants in salt and alkali, improve the content of chlorophyll and proline in rice, improve the antioxidant enzyme activity, and reduce the content of malondialdehyde; in addition, the Providencia sp. has the ability of nitrogen fixation, the Pseudoclavibacter sp. has the ability of iron production, and the Planococcus sp. has the abilities of iron production and phosphorus dissolution.
Owner:YANGZHOU UNIV

Preparation method and application of whole-plant fried ginseng

PendingCN122075563AImprove antioxidant capacityIncreased swimming time to exhaustionAntinoxious agentsFood scienceBiotechnologyLactate dehydrogenase
The invention relates to the field of food processing, in particular to a preparation method of whole-plant fried ginseng and application of the whole-plant fried ginseng in preparation of drugs or food for resisting oxidation and relieving fatigue. The method comprises the following steps: fresh ginseng is taken and cleaned, rhizome, main roots and fibrous roots are separated, the main roots are cut into slices or segments, the rhizome, the slice-shaped main roots or the segment-shaped main roots and the fibrous roots are respectively placed in oil to be fried, and when the rhizome, the slice-shaped main roots or the segment-shaped main roots and the fibrous roots are golden yellow, the rhizome, the main roots and the fibrous roots are fished out, drained off oil and cooled. The antioxidant activity of the fried ginseng slices and segments is improved. Compared with fresh ginseng, the deep-fried ginseng slices and segments can significantly prolong exhaustive swimming time of load-bearing mice, significantly improve liver / muscle glycogen, lactic dehydrogenase content and superoxide dismutase activity, reduce lactic acid, urea nitrogen and malondialdehyde content, and have a significant anti-fatigue effect. According to the method, dryness of fresh ginseng can be removed, the eating fragrance can be improved, the fried ginseng product is instant and convenient to eat, and the fried ginseng product is matched with barbecue kebabs and stewed together with livestock and poultry meat, so that the fried ginseng product is delicious and health-care.
Owner:YANBIAN UNIV

A Yao medicine bath effervescent tablet compound preparation with anti-rheumatoid arthritis effect and a preparation process thereof

This invention belongs to the field of traditional Chinese medicine preparations, and relates to the preparation method and application of a compound preparation of Yao Yu effervescent tablets with anti-rheumatoid arthritis effect. The compound preparation comprises the following traditional Chinese medicine components: 4 parts by weight of Dioscorea cirrhosa, 3 parts by weight of Tinleaf Vine, 2 parts by weight of Camphor Tree, 2 parts by weight of Rhus chinensis, 3 parts by weight of Rhododendron molle, 1 part by weight of Ephedra sinica, 2 parts by weight of Semi-Acer palmatum, 2 parts by weight of Gynostemma pentaphyllum, and 1 part by weight of Cinnamomum cassia. The preparation steps include: placing Dioscorea cirrhosa, Tinleaf Vine, Camphor Tree, Rhus chinensis, Rhododendron molle, Gynostemma pentaphyllum, Semi-Acer palmatum, Gynostemma pentaphyllum, and Cinnamomum cassia in 6000 parts by weight of 70% ethanol. Extract for 2 hours, repeat three times, filter, and combine the filtrates; concentrate, freeze-dry, pulverize, and pass through an 80-mesh sieve for later use; mix 27.5% freeze-dried powder with 26.45% citric acid, 34.11% sodium bicarbonate, 5.61% PEG6000, and 6.33% lactose evenly, pass through an 80-mesh sieve, and prepare a soft mass using anhydrous ethanol as a wetting agent; pass the soft mass through a 20-mesh sieve and dry at 37℃ for 30 minutes to obtain compound preparation granules; granulate through a 20-mesh sieve for granulation, add lubricant PEG6000 and mix evenly; compress into tablets to obtain compound preparation effervescent tablets. This invention, through pharmacological experiments, confirms that the Yaoyu effervescent tablet compound preparation has a good anti-rheumatoid arthritis effect: it can reduce local inflammatory mediators and serum IL-1β, IL-6, TNF-α, and PEG2 levels, downregulate MDA and increase SOD to improve oxidative stress, inhibit the expression of MMP3, COX-2, and P38 proteins in the synovial membrane, and reduce pathological tissue damage. The medium and high dose groups showed the best effect, and it has a good therapeutic and protective effect on the ankle joint of AA rats, with good clinical application value.
Owner:GUANGXI UNIV OF CHINESE MEDICINE

Application of taSCAMP17 and recombinant overexpression vector thereof in improving salt tolerance of plants

This invention belongs to the field of genetic engineering technology, specifically involving TaSCAMP17 The application of its recombinant overexpression vector in improving plant salt tolerance, the TaSCAMP17 The nucleotide sequence is shown in SEQ ID NO.1, and the amino acid sequence is shown in SEQ ID NO.2. This invention will... TaSCAMP17 Functional validation was performed in Arabidopsis thaliana after overexpression, and the results showed that overexpression... TaSCAMP17 The salt tolerance of wild-type Arabidopsis thaliana is significantly improved, therefore TaSCAMP17 It plays a positive regulatory role in wheat salt tolerance, providing a theoretical basis and gene resources for wheat molecular breeding, and is of great significance for obtaining salt-tolerant and high-yielding lines and improving wheat salt tolerance in the future.
Owner:QINGDAO AGRI UNIV

A Rongchang pig-derived Lactobacillus reuteri and its application in piglet intestinal anti-oxidation

The present invention discloses a Rongchang pig-source Lactobacillus reuteri and its application in piglet intestinal antioxidant treatment. The Lactobacillus reuteri is classified and named Lactobacillus reuteri RS‑X‑811, which was registered and preserved in the General Microbiology Center of China National Microbiological Culture Collection on November 23, 2023, with the preservation number CGMCC No.29110. The present invention uses fresh feces of Chongqing local Rongchang pigs as samples, screens out a Lactobacillus reuteri RS-X-811, which has a certain inhibitory effect on Escherichia coli, Staphylococcus aureus and Salmonella, and has excellent acid resistance and choline resistance. In addition, the fermentation supernatant, bacterial suspension and cell-free extract of RS-X-811 have certain DPPH free radical, superoxide anion free radical, hydroxyl free radical scavenging ability and certain reducing ability. Adding RS-X-811 to piglet feed can significantly promote the intestinal development of weaned piglets, improve the absorption capacity of the intestine, and also improve the antioxidant capacity of the intestine of weaned piglets.
Owner:SOUTHWEAT UNIV OF SCI & TECH +1

Process for the preparation of edible oils having neuroprotective effects and / or alleviating ad

PendingCN122686378AKeep the burnt smellRetain mild nature
The application belongs to the technical field of natural product extraction and application, and discloses a preparation method of edible oil with nerve protection and / or AD alleviation, comprising: frying raw gardenia fruits at a temperature of 140-160 DEG C for 10-20 minutes, cooling, physically pressing the obtained scorched gardenia fruits below 50 DEG C, and obtaining edible oil after filtering and removing impurities. The prepared edible oil can significantly protect nerve cells damaged by H2O2, can significantly improve the spatial memory and learning ability in an APP / PS1 mouse model, can reduce the oxidative stress damage of brain tissue, can inhibit nerve inflammation, and can protect the structure and function of neurons. The preparation process is simple, green and safe, the raw material is a homologous plant of medicine and food, the source is wide, and the application provides a safe and effective daily dietary intervention way for the prevention and treatment of Alzheimer's disease and other neurodegenerative diseases.
Owner:ZHEJIANG FORESTRY UNIVERSITY

Preparation method of soybean polypeptide with antioxidant and antagonistic lead damage effects

The present application relates to a kind of soybean polypeptide preparation method with antioxidant and antagonistic lead damage effect.The soybean polypeptide prepared in the present application has good DPPH free radical clearance rate, ABTS free radical clearance rate and Fe3+ reduction capacity in vitro;It can also alleviate the case that the body weight of mouse is slowly increased due to lead exposure, improve the learning and memory ability of lead exposure mouse, alleviate the organ damage of mouse caused by lead exposure, enhance the level of reduced glutathione, superoxide dismutase and catalase of organism, and alleviate the abnormal increase of malondialdehyde caused by lead exposure.The soybean polypeptide prepared in the present application has good in vitro antioxidant capacity, and has antagonistic effect on oxidative stress caused by lead exposure mouse, and can be used as non-toxic and harmless natural antioxidant.For the development of natural antioxidant food, it has far-reaching application prospect, and also provides a new feasible idea for the combined application of bioinformatics technology and traditional enzymatic technology.
Owner:TIANJIN UNIV OF SCI & TECH +1

Pseudomonas kkerchii WF3, microbial fertilizer for saline-alkali soil as well as preparation method and application of microbial fertilizer

The invention provides Pseudomonas kirscheri WF3, a microbial fertilizer for saline-alkali soil and a preparation method and application of the microbial fertilizer, and belongs to the technical field of biological composting. The invention provides a preparation method of a microbial fertilizer for saline-alkali soil. The preparation method comprises the following steps: (1) preparing a fertilizer carrier comprising a decomposed organic fertilizer, humic acid, attapulgite powder and polyglutamic acid; and (2) inoculating pseudomonas kirschner WF3 into the fertilizer carrier, and carrying out sealed fermentation to obtain the microbial fertilizer for saline-alkali soil. Pseudomonas kirschner WF3 which has exopolysaccharide and organic acid production capacity and can survive in a strong saline-alkaline environment is adopted for fermentation of a fertilizer carrier, the prepared microbial organic fertilizer can effectively improve the content of organic carbon, total nitrogen and water-stable large aggregates (larger than 2.5 mm) in soil, increase the yield of corn, reduce the pH and total salt content of the soil, and improve the yield of corn. The improvement effect on the saline-alkali soil is obvious.
Owner:INST OF SOIL FERTILIZER & WATER SAVING AGRI GANSU ACAD OF AGRI SCI

Antioxidant antifreeze protein derived from Tibetan pig and application of antioxidant antifreeze protein in frozen semen diluent

ActiveCN119490565Ahigh activityImprove pregnancy ratePeptidesDead animal preservationSuper oxide dismutaseTibetan pig
According to the antioxidant antifreeze protein from Tibetan pigs, the protein is added into a cryopreservation solution, so that the activity of peroxidase, catalase, superoxide dismutase and glutathione peroxidase after the sperms of the Tibetan pigs are frozen and unfrozen can be remarkably improved, the total antioxidant capacity of the sperms is remarkably enhanced, and the antifreeze effect of the sperms is improved. The active oxygen level and malondialdehyde content in sperm cells are obviously reduced. The cryoprotectant provided by the invention can greatly improve the motility rate and activity of unfrozen sperms and ensure the stability of the motility rate and activity of the unfrozen sperms; the pregnancy rate of artificial insemination of the frozen semen of the Tibetan pigs is increased, and the quality of the frozen semen is greatly improved. In addition, exogenous antifreeze protein does not need to be added into the preserving fluid, so that essential nutrient substances for sperm metabolism are guaranteed, and meanwhile, damage and pollution risks caused by exogenous substances to sperms are reduced.
Owner:BEIJING TYAR BIOLOGIC TECH CO LTD +1

New uses of Artemisia annua seeds, a compound medicinal and edible compound for relieving hangovers and protecting the liver, chewable tablets and their preparation process

PendingCN122075569Areduce spreadEnhance the anti-alcoholic and liver-protecting effectDigestive systemAntinoxious agentsBiotechnologyEthanol absorption
This invention discloses a novel use of Artemisia annua seeds, a medicinal and edible compound composition for relieving hangovers and protecting the liver, chewable tablets, and their preparation process. This invention is the first to discover that the mucilage in Artemisia annua seeds slows down ethanol diffusion through a dual mechanism of physical adsorption and three-dimensional network blockage, thus slowing down the rate of ethanol absorption in the digestive tract, reducing the peak blood plasma concentration, and delaying or prolonging the time of intoxication. Therefore, it can be used in the preparation of health products / functional foods that protect the stomach, prevent intoxication, and delay alcohol absorption. Based on this discovery, this invention provides a medicinal and edible compound composition for relieving hangovers and protecting the liver, composed of 10-15 parts by weight of Pueraria lobata, 10-15 parts by weight of Hovenia dulcis, 8-10 parts by weight of Lilium brownii, 4-8 parts by weight of Poria cocos, 4-8 parts by weight of Dioscorea opposita, and 4-8 parts by weight of Artemisia annua seeds. Furthermore, to balance rapid effectiveness and compliance, it is formulated as a chewable tablet. This chewable tablet can significantly prolong the time of intoxication and shorten the sobering-up time, and is significantly superior to the group lacking Artemisia annua seeds in terms of antioxidant indicators (SOD, GSH, MDA) and hangover relief effect.
Owner:JIYANG COLLEGE OF ZHEJIANG A & F UNIV

Bioactive peptide capable of improving holothurian summer passing ability and application thereof

The application discloses a kind of biological active peptide capable of improving sea cucumber summer passing capacity and its preparation method and application.The biological active peptide is obtained by extracting, enzyme hydrolysis, separation and purification using tuna meat as raw material, and the amino acid sequence of the active peptide is MADFFTRL.Test shows that the biological active peptide can improve the survival rate of sea cucumber under high temperature stress, enhance the activities of SOD, CAT and other antioxidant enzymes, reduce the content of MDA, reduce the oxidative damage caused by high temperature, thereby improving the heat resistance and safe summer passing capacity of sea cucumber.The biological active peptide can be used for preparing sea cucumber feed additive or functional feed, and has good application prospect.
Owner:山东省渔业发展和资源养护总站

Preparation of immobilized material based on phosphate solubilizing bacteria and application of immobilized material in soil

The invention discloses preparation of an immobilized material based on phosphate solubilizing bacteria and application of the immobilized material in soil, and belongs to the technical field of soil remediation microbial agents. The material takes bacillus megatherium and lignin as core functional components, and takes a mixed system of sodium alginate and sodium carboxymethyl cellulose as a carrier. The immobilized material is high in mechanical strength, good in stability and excellent in mass transfer efficiency, meanwhile, insoluble phosphorus is activated through metabolites secreted by bacillus megatherium, and the content of available phosphorus in soil is increased. The material can also improve the soil structure, improve the cation exchange capacity and the organic matter content, enhance the activities of peroxidase and superoxide dismutase of the rice, reduce the content of malonaldehyde, relieve oxidative damage caused by Cd stress, reduce Cd accumulation of the rice from the source and guarantee normal growth of the rice.
Owner:ZHEJIANG FORESTRY UNIVERSITY

Lactobacillus plantarum IOB602 for regulating bone metabolism and application thereof

ActiveCN119157912BReduce MDA contentlower levelBacteriaMetabolism disorder
The present invention provides a plant lactobacillus IOB602 for regulating bone metabolism and its application, and relates to the field of microbial technology. Lactiplantibacillus plantarum , was deposited in the General Microbiology Center of China Microorganism Culture Collection Committee on June 29, 2018, referred to as CGMCC, and the deposit address is No. 3, No. 1 Beichen West Road, Chaoyang District, Beijing, and the deposit number is CGMCC No. 16021. The bacteria reduces the content of lipid peroxidation product malondialdehyde and increases the content of antioxidant enzymes, which is of great significance for reducing ROS damage to bone cells, regulating the balance of osteoblasts and osteoclasts, improving bone metabolism, and preventing and treating diabetic osteoporosis.
Owner:TIANJIN INNOORIGIN BIOLOGICAL TECH CO LTD +1

A method for preparing wholemeal flour stabilized against lipase and lipoxygenase activity

The application discloses a preparation method of whole wheat flour with controlled lipase and lipoxygenase activity, and relates to the technical field of whole wheat flour processing and storage. The method comprises the following steps: adopting DBD plasma to treat the bran of wheat grains, and then directly grinding the wheat grains to obtain the whole wheat flour. The method controls the lipase and lipoxygenase in the bran of the wheat grains, thereby stabilizing the whole wheat flour, prolonging the storage period of the whole wheat flour, and improving the nutritional quality and processing quality of the whole wheat flour. The DBD plasma treatment is performed at a power of 300-500 W for 60-180 s.
Owner:HENAN UNIVERSITY OF TECHNOLOGY

Hybrid tuliptree salt-tolerant related protein LcCIPK25 and coding gene and application thereof

PendingCN122542513ALow yellowing ratioreduce yellowing
This invention relates to a salt tolerance-related protein, LcCIPK25, and its encoding gene in hybrid tulip tree (Liriodendron tulipifera), and its applications, belonging to the field of plant genetic engineering technology. The amino acid sequence of this protein is shown in SEQ ID NO.2, and the nucleotide sequence of the gene encoding this protein is shown in SEQ ID NO.1. This invention also provides a recombinant expression vector containing the aforementioned nucleic acid molecule, a recombinant host cell, and its application in improving plant salt tolerance. Overexpression of the aforementioned nucleic acid molecule in hybrid tulip tree can maintain CAT activity, alleviate leaf yellowing and oxidative damage under high salt stress, significantly reduce MDA content, and effectively enhance the plant's salt tolerance.
Owner:NANJING FORESTRY UNIV

Application of PvFIP37 protein and related biological materials thereof in regulation and control of cadmium tolerance of plants

ActiveCN119506346Apromote growthIncreased superoxide dismutase activityPlant peptidesFermentationBiotechnologyAssociated organism
The invention discloses application of PvFIP37 protein and related biological materials thereof in regulation and control of cadmium tolerance of plants. According to the invention, the PvFIP37 gene is cloned from switchgrass, and the PvFIP37 overexpressed switchgrass is successfully constructed. The analysis on the phenotype of the PvFIP37 overexpressed switchgrass under cadmium stress finds that compared with wild type switchgrass, the cadmium tolerance of the switchgrass can be enhanced by increasing the expression quantity of the PvFIP37 gene, which indicates that the PvFIP37 has the function of regulating and controlling the cadmium tolerance of plants. The switchgrass PvFIP37 gene provided by the invention can be used as an excellent gene resource, is widely applied to the field of genetic breeding of gramineous grass or other crops, and has important significance on understanding of tolerance of plants under heavy metal stress.
Owner:CHINA AGRI UNIV

A planting method for relieving drought of wheat based on combined application of SiQD seed dressing and halophilic bacillus

ActiveCN121336662Bpromote growthImprove drought toleranceBiotechnologyWater-use efficiency
The application discloses a planting method for relieving drought of wheat based on combined application of SiQDs seed dressing and halophilic bacillus, and belongs to the technical field of agricultural planting. The application discloses a planting method for relieving drought of wheat based on combined application of SiQDs seed dressing and halophilic bacillus, which comprises the following steps: using silicon quantum dots (SiQDs) for seed dressing treatment of wheat seeds, then planting the seed-dressed wheat seeds in soil, and applying halophilic bacillus agent during the growth of the wheat. The combined application of SiQDs and halophilic bacillus GS127 can better promote the root development of wheat under drought stress, increase the content of proline and soluble sugar in the wheat, reduce the content of malondialdehyde, enhance the drought resistance of the wheat, effectively promote the growth of the wheat, and improve the yield and water use efficiency, and therefore has excellent application potential in the production in agricultural wheat drought areas.
Owner:NORTHWEST A & F UNIV