26 results about "Ephedra sinica" patented technology

A traditional Chinese medicine composition for treating acute and chronic inflammation of the ear, nose, and throat, and its preparation method, characterized in that, by weight, it is made from the following traditional Chinese medicinal materials: 10-30 parts of Lycium chinense root bark, 8-30 parts of Gardenia jasminoides, 10-30 parts of Sanguisorba officinalis root bark, 8-25 parts of Schizonepeta tenuifolia root bark, 6-16 parts of Angelica dahurica root bark, 10-35 parts of Asparagus cochinchinensis root bark, 11-35 parts of Platycodon grandiflorus root bark, 7-46 parts of Paeonia lactiflora root bark, 8-46 parts of Rehmannia glutinosa root bark, and 5-10 parts of Oroxylum indicum root bark. 14 parts of the following ingredients are used: Astragalus membranaceus 12-50 parts, Magnolia biondii 10-30 parts, Trichosanthes kirilowii 10-35 parts, Stellaria dichotoma 5-20 parts, Imperata cylindrica 7-30 parts, Fagopyrum dibotrys 10-35 parts, Coix lacryma-jobi 13-60 parts, Lepidium apetalum 5-15 parts, Gypsum fibrosum 14-50 parts, Sophora tonkinensis 3-20 parts, Lonicera japonica 12-50 parts, Xanthium sibiricum 6-35 parts, Ephedra sinica 6-30 parts, and Styrax benzoin 1-3 parts. After grinding into powder, the mixture is steamed with rice wine to obtain pills. The principle of treating all three (ear, nose, and throat) simultaneously, considering the anatomical structure and physiological function of the ear, nose, and throat, aims to reduce cross-infection, promote recovery, and achieve ideal medicinal properties.

This invention relates to the field of traditional Chinese medicine technology, and more particularly to the application of a traditional Chinese medicine composition in the preparation of drugs for the prevention and treatment of lung injury. The traditional Chinese medicine composition includes Astragalus membranaceus, Eupolyphaga sinensis, Morus alba root bark, Fritillaria cirrhosa, Perilla frutescens seed, Lepidium apetalum seed, Prunus armeniaca seed, Pheretima aspergillum, Ephedra sinica, and Clematis chinensis. Experiments show that this traditional Chinese medicine composition can significantly reduce the level of the inflammatory factor TNF-α, decrease the lung index, and alleviate pathological damage to lung tissue, and can be used for the prevention and treatment of lung injury.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating chronic obstructive pneumonia and a pharmaceutical preparation. The traditional Chinese medicine composition comprises blackberry lily, honey-fried ephedra, dried ginger, asarum, honey-fried aster, honey-fried tussilago farfara, exocarpium citri rubrum, schisandra chinensis, fried semen raphani, perillaseed, semen brassicae and liquorice. The traditional Chinese medicine composition and the pharmaceutical preparation provided by the invention are used for patients with chronic obstructive pneumonia, can recover the pulmonary ventilation function, effectively inhibit inflammatory response in the body and promote lung tissue injury repair, and have a relatively good treatment effect on chronic obstructive pneumonia.

This invention relates to the field of traditional Chinese medicine preparation technology, and particularly to a traditional Chinese medicine composition for treating cancer pain and numbness, as well as its preparation and application. This invention designs a traditional Chinese medicine composition for cancer pain and numbness, comprising: *Houttuynia cordata*, *Aconitum carmichaelii*, processed *Aconitum carmichaelii*, centipede, *Astragalus membranaceus*, *Ephedra sinica*, clove, frankincense, ephedra, menthol, and azone. The scientifically formulated combination of principal, assistant, and adjuvant herbs allows for multi-target action on both "cancer pain" (inflammation, compression, nerve infiltration) and "CIPN" (nerve damage), resulting in a superior analgesic effect, while also possessing anti-inflammatory, anti-swelling, potential tumor-suppressing, and nerve-repairing effects. The traditional Chinese medicine composition is prepared into a traditional Chinese medicine ointment, which is administered transdermally, allowing a high concentration of the drug to act directly on the lesion, avoiding the systemic side effects (addiction, constipation, etc.) associated with oral opioids. This is especially suitable for patients who cannot take oral opioids or cannot tolerate them.

This invention discloses a library of traditional Chinese medicine (TCM) compositions based on general and local anesthesia mechanisms, along with various dosage forms and preparation methods. The invention constructs a systematic library of TCM anesthetic compositions: the general anesthetic composition consists of extracts from herbs such as Datura stramonium, Datura stramonium, processed Aconitum carmichaelii, processed Aconitum kusnezoffii, Saussurea involucrata, Jasminum sambac root, Rhododendron molle, and Sanqie Sanqie; the local anesthetic composition consists of extracts from herbs such as Asarum heterotropoides, Murraya paniculata, Ephedra sinica, Toad venom, and Corydalis yanhusuo. This invention further develops the above compositions into various modern dosage forms, including injections, tablets, capsules, and sprays. In particular, this invention innovatively introduces a clove-cinnamon natural preservative and flavoring system to replace chemical preservatives. In terms of preparation technology, advanced technologies such as supercritical CO2 extraction, microwave-assisted extraction, nano-embedding, and nanoemulsions are integrated, and a self-extraction scheme is adopted to achieve controllable quality and cost. Simultaneously, a quality detection method based on HPLC fingerprinting is established. This invention achieves full-scenario coverage of anesthesia and analgesia, from general to local, from emergency to routine care, with outstanding advantages of safety, effectiveness, and controllable quality.

A traditional Chinese medicine composition for treating Hashimoto's thyroiditis comprises the following raw materials in the indicated weight ratios: 50-200 parts Rehmannia glutinosa (processed), 10-60 parts Cinnamomum cassia, 30-100 parts Ephedra sinica, 10-60 parts Cervi cornu slices, 10-60 parts Zingiber officinale (dried), 30-80 parts Glycyrrhiza uralensis (processed), 50-200 parts Paeonia lactiflora (white), 50-200 parts Paeonia veitchii (red), 30-100 parts Paeonia suffruticosa (moutan bark), 50-200 parts Codonopsis pilosula, 50-200 parts Angelica sinensis, 50-200 parts Prunus persica, and 30-100 parts Carthamus tinctorius. The preparation method is as follows: Place Rehmannia glutinosa, Cinnamomum cassia, Ephedra sinica, deer antler slices, dried ginger, prepared licorice root, white peony root, red peony root, peony bark, Codonopsis pilosula, Angelica sinensis, peach kernel, and safflower in a container, add 8 times the total weight of the herbs in cold water, soak for 30 minutes to fully moisten the herbs, bring to a boil over high heat, then simmer over low heat for another 30 minutes; for the second decoction, filter out the liquid from the first decoction, add the remaining herbs and 6 times the total weight of the herbs in warm water, just enough to cover the herbs; soak for 30 minutes, bring to a boil over high heat, then simmer over low heat for another 20 minutes; after the decoction is completed, combine the two decoctions, filter out the dregs, and obtain the traditional Chinese medicine decoction.

This invention belongs to the field of traditional Chinese medicine preparations, and relates to the preparation method and application of a compound preparation of Yao Yu effervescent tablets with anti-rheumatoid arthritis effect. The compound preparation comprises the following traditional Chinese medicine components: 4 parts by weight of Dioscorea cirrhosa, 3 parts by weight of Tinleaf Vine, 2 parts by weight of Camphor Tree, 2 parts by weight of Rhus chinensis, 3 parts by weight of Rhododendron molle, 1 part by weight of Ephedra sinica, 2 parts by weight of Semi-Acer palmatum, 2 parts by weight of Gynostemma pentaphyllum, and 1 part by weight of Cinnamomum cassia. The preparation steps include: placing Dioscorea cirrhosa, Tinleaf Vine, Camphor Tree, Rhus chinensis, Rhododendron molle, Gynostemma pentaphyllum, Semi-Acer palmatum, Gynostemma pentaphyllum, and Cinnamomum cassia in 6000 parts by weight of 70% ethanol. Extract for 2 hours, repeat three times, filter, and combine the filtrates; concentrate, freeze-dry, pulverize, and pass through an 80-mesh sieve for later use; mix 27.5% freeze-dried powder with 26.45% citric acid, 34.11% sodium bicarbonate, 5.61% PEG6000, and 6.33% lactose evenly, pass through an 80-mesh sieve, and prepare a soft mass using anhydrous ethanol as a wetting agent; pass the soft mass through a 20-mesh sieve and dry at 37℃ for 30 minutes to obtain compound preparation granules; granulate through a 20-mesh sieve for granulation, add lubricant PEG6000 and mix evenly; compress into tablets to obtain compound preparation effervescent tablets. This invention, through pharmacological experiments, confirms that the Yaoyu effervescent tablet compound preparation has a good anti-rheumatoid arthritis effect: it can reduce local inflammatory mediators and serum IL-1β, IL-6, TNF-α, and PEG2 levels, downregulate MDA and increase SOD to improve oxidative stress, inhibit the expression of MMP3, COX-2, and P38 proteins in the synovial membrane, and reduce pathological tissue damage. The medium and high dose groups showed the best effect, and it has a good therapeutic and protective effect on the ankle joint of AA rats, with good clinical application value.

The invention relates to a method for extracting ephedrine E from herba ephedrae, which can effectively extract ephedrine E from herba ephedrae and realize application in preparation of medicines for treating pulmonary arterial hypertension. The preparation method comprises the following steps: taking dried roots and rhizomes of ephedra sinica stapf, extracting by adopting a water decoction method, concentrating under reduced pressure to obtain total extract, dispersing with water, eluting, dissolving with methanol, stirring with silica gel, carrying out gradient elution, identifying, merging the same fractions, loading a target component on column chromatography, eluting, purifying, collecting the fractions within retention time, and drying to obtain ephedrine E; the preparation method is simple, the ephedrine E is easy to industrially prepare, the medicinal value of ephedra is expanded, the application in preparation of the medicine for treating the pulmonary arterial hypertension is realized, and the ephedrine E is a great innovation in preparation of the medicine for treating the pulmonary arterial hypertension and has practical popularization and application value.

This invention relates to the application of a traditional Chinese medicine composition in a drug for ulcerative colitis, characterized in that the traditional Chinese medicine composition comprises: 1-100 parts of Magnolia officinalis, 1-100 parts of Areca catechu (roasted), 1-100 parts of Amomum villosum (roasted), 1-100 parts of Ephedra sinica, 1-100 parts of Prunus armeniaca (bitter), 1-100 parts of Notopterygium incisum, 1-100 parts of Zingiber officinale (fresh), 1-100 parts of Pogostemon cablin, 1-100 parts of Eupatorium fortunei, 1-100 parts of Atractylodes lancea, 1-160 parts of Poria cocos, 1-120 parts of Atractylodes macrocephala, 1-100 parts of Gypsum fibrosum, 1-100 parts of Crataegus pinnatifida (roasted), 1-100 parts of Massa fermentata (roasted), 1-100 parts of Hordeum vulgare (roasted), 1-100 parts of Pheretima aspergillum, 1-100 parts of Cynanchum paniculatum, 1-100 parts of Dryopteris crassirhizoma, and 1-100 parts of Lepidium apetalum.

The application discloses a method for determining the content of aconite alkaloids in a traditional Chinese medicine composition containing Ramulus Cinnamomi, which comprises the following steps: detecting test sample solution and control sample solution of the traditional Chinese medicine composition, and obtaining the content information of the control sample of the traditional Chinese medicine composition according to the detection result; wherein the traditional Chinese medicine composition comprises Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae, Ephedra, Rhizoma Zingiberis Recens, Rhizoma Atractylodis Macrocephalae, Rhizoma Anemarrhenae, Radix Saposhnikoviae and Heishunpian, and the control sample is benzoyl neoorientaline, benzoyl orientaline, benzoyl hypoorientaline, neoorientaline, hypoorientaline and aconitine. The application carries out the content monitoring research on the monoester type alkaloids of Heishunpian medicinal flavor in the reference sample of the traditional Chinese medicine composition containing Ramulus Cinnamomi, and carries out the limited control research on the diester type alkaloids, and the research on the reference sample of the traditional Chinese medicine composition containing Ramulus Cinnamomi is carried out from the multiple dimensions of safety and effectiveness, and has important quality control significance.

The invention provides an application of a traditional Chinese medicine composition in preventing influenza A virus replication at a cellular level. The traditional Chinese medicine composition is prepared from the following raw materials: cortex magnoliae officinalis, scorched betel nut, roasted amomum tsao-ko, herba ephedrae, semen armeniacae amarae, notopterygium root, ginger, pogostemon cablin, herba eupatorii, rhizoma atractylodis, bighead atractylodes rhizome, poria cocos, scorched hawthorn fruit, scorched medicated leaven, scorched malt, rhizoma dryopteris crassirhizomae, radix cynanchi paniculati, earthworm, gypsum and semen lepidii. It is confirmed for the first time that the traditional Chinese medicine composition can inhibit replication of influenza A viruses (such as influenza A H1N1 viruses) on the cellular level, has an obvious inhibiting effect on influenza A viruses, has the advantages of being clear in effective component, obvious in drug effect, small in taking dosage and the like, is good in application prospect, is suitable for industrial large-scale production, and has wide application prospects. The traditional Chinese medicine composition can be used for preparing medicines for preventing or treating influenza A virus infection, and has good economic benefits and social benefits.

The invention relates to the technical field of plant biology, and particularly discloses an agrobacterium rhizogenes-mediated tissue-culture-free euphorbia kansui transformation method, which is technically characterized by comprising the following steps: S1, constructing a pCAMBIA1300:: 35S-EkHMGR-GFP recombinant vector by using a specific primer; s2, establishing a euphorbia kansui regeneration system as an identification basis for obtaining a transgenic plant from an expanded root segment; s3, infecting wounds through agrobacterium rhizogenes K599 to induce hairy roots, and regenerating transgenic plants by utilizing expanded root segments. A set of rapid and stable euphorbia kansui genetic transformation system which is mediated by agrobacterium rhizogenes and does not need tissue culture is established, recombinant plasmids carrying a target gene EkHMGR are introduced into euphorbia kansui by the agrobacterium rhizogenes to obtain transgenic hairy roots, and positive plants obtained by culturing expanded root segments are transplanted. The transformation method constructed by the invention has potential application value on genetic transformation of euphorbia kansui and also has important reference value on genetic transformation of other plants, and research results provide theoretical guidance for promoting synthesis and accumulation of euphorbia kansui key medicinal component euphorbia dienol.

The invention provides a traditional Chinese medicine composition and application thereof in preparation of a medicine for treating reflux esophagitis, and relates to the technical field of traditional Chinese medicine pharmacy. According to the traditional Chinese medicine composition, thunberg fritillary bulb, fructus evodiae and fingered citron serve as monarch drugs, inula flower, buckeye, rhizoma nardostachyos, clove, amomum tsao-ko and membrane of hen egg serve as ministerial drugs, nacre mother of pearl, cortex fraxini, felwort, sweet-scented osmanthus and reed rhizome serve as adjuvant drugs, licorice serves as conductant drugs, and all the drugs are combined to achieve the effects of soothing the liver and harmonizing the stomach, calming the adverse-rising energy, relieving acid and regulating cold and heat. The traditional Chinese medicine composition can significantly improve the esophagitis index of RE rats, has an obvious inhibition effect on inflammatory injury, can significantly improve the pathological morphology of esophageal tissues of the RE rats, and achieves good anti-inflammatory and therapeutic effects on the RE rats. Meanwhile, the traditional Chinese medicine composition can remarkably improve and relieve clinical symptoms such as sour regurgitation, heartburn, abdominal distension and belching of reflux esophagitis patients, and the attack frequency of the clinical symptoms is reduced. The traditional Chinese medicine composition disclosed by the invention is expected to be further developed and popularized as a medicine for treating reflux esophagitis.

The present invention relates to a method for treating a coronavirus infectious disease and a complication thereof, including: administering a Chinese medicine composition to a subject in need thereof; wherein, the Chinese medicine composition is an extract of a first mixture including Ephedra sinica, Armeniacae Semen amarum, Glycyrrhizae radix et rhizoma, Gypsum fibrosum, Descurainiea semen, stephaniae Tetrandrae radix, Scutellariae radix, Poria, rhizoma alismatis, Polyporus umbellatus, Atractylodis rhizoma, Asteris radix et rhizoma, Tussilago farfara, Pinelliae rhizoma, and Rhei radix et rhizoma.

The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine compound preparation for enhancing transdermal absorption and antibacterial activity as well as preparation and application thereof. According to the preparation, on the basis of classic components of patrinia, radix clematidis and ephedra, functional auxiliary materials are added to achieve performance improvement, and the preparation specifically comprises the following raw materials in parts by mass: 20 parts of patrinia, 15 parts of radix clematidis, 15 parts of ephedra, 0.1-0.5 part of a transdermal enhancer, 3-10 parts of a nano-liposome carrier and 0.2-0.8 part of a natural antibacterial synergist. The transdermal enhancer is prepared from menthol, laurocapram and D-limonene; the nano-liposome carrier comprises soybean lecithin, cholesterol and polyethylene glycol. Through the synergistic effect of the nano-liposome carrier, the composite transdermal enhancer and the natural antibacterial synergist, the nano-liposome can be flexibly matched with multiple dosage forms such as lotion, gel, cream and spray, the transdermal absorption of effective components is remarkably improved, the antibacterial spectrum is widened, and the inhibition effect on drug-resistant strains is enhanced.

The invention discloses a traditional Chinese medicine nano composition as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine preparations. The preparation method comprises the following steps: mixing the traditional Chinese medicine raw materials according to the formula ratio, soaking with water, decocting, and filtering with gauze to obtain filtrate; performing differential centrifugation on the filtrate, and taking supernatant; carrying out ultracentrifugation on the supernatant and then taking a precipitate; and resuspending the precipitate with water to obtain the traditional Chinese medicine nano composition. Wherein the traditional Chinese medicine raw materials comprise radix bupleuri, pinellia ternate, codonopsis pilosula, liquorice, scutellaria baicalensis, ginger, jujube, ephedra, cassia twig, radix paeoniae alba, asarum, schisandra chinensis, rhizoma zingiberis, periostracum cicada, stiff silkworm, turmeric, rheum officinale and solidago decurrens. The traditional Chinese medicine nano composition provided by the invention is scientific in compatibility, has the effects of eliminating evil and strengthening the body resistance, not only aims at exterior syndromes of exogenous wind-cold and internal water retention, but also recuperates a shaoyang central machine and reconciles qi activity, realizes the comprehensive curative effects of relieving exterior and interior, regulating cold and heat and treating qi and blood simultaneously, and has remarkable treatment advantages on respiratory tract infectious diseases such as seasonal influenza.

The invention discloses meridian activating stone needle warming and dredging medicinal oil and a preparation method thereof, the meridian activating stone needle warming and dredging medicinal oil comprises medicinal components and natural vegetable oil, and the ratio of the medicinal components to the natural vegetable oil is 1g: 1-5mL; the medicine components comprise the following components in parts by weight: 25-35 parts of processed semen strychni, 40-50 parts of flos carthami, 40-50 parts of ginger processed cortex magnoliae officinalis, 55-65 parts of bran-fried fructus aurantii immaturus, 25-35 parts of processed fructus evodiae, 85-95 parts of raw semen coicis, 25-35 parts of peach kernels, 25-35 parts of radix angelicae sinensis, 25-35 parts of cortex cinnamomi, 10-20 parts of herba ephedrae and 25-35 parts of rhizoma chuanxiong. The cure rate of an intervention group adopting the medicinal oil disclosed by the invention is 42.9%, the total effective rate is 100%, and after intervention, the clinical curative effect and gastrointestinal symptom score of a patient in a test group are obviously superior to those of a control group (Plt; therefore, the medicinal oil combined with stone needle therapy can relieve clinical symptoms of patients, reduce the score of gastrointestinal symptoms and improve the clinical curative effect.

This invention provides a traditional Chinese medicine composition for treating porcine reproductive and respiratory syndrome (PRRS) and its application. The composition comprises Scutellaria baicalensis, Anemarrhena asphodeloides, Rheum palmatum, Gypsum fibrosum, Houttuynia cordata, Mentha haplocalyx, Atractylodes lancea, Citrus reticulata peel, Poria cocos, Magnolia officinalis, Pueraria lobata, Ligustrum lucidum, Ephedra sinica, Prunus armeniaca, Gynostemma pentaphyllum, Astragalus membranaceus, Psoralea corylifolia, and Glycyrrhiza uralensis. This composition is formulated under the guidance of traditional Chinese veterinary medicine's syndrome differentiation and treatment principles. The combined effects of these herbs are significant in treating PRRS and other damp-heat diseases. Furthermore, this traditional Chinese medicine preparation does not contain antibiotics, is safe and effective, and does not induce drug resistance.

A method for treating pleural effusion includes: administering a Chinese medicine composition to a subject in need thereof; wherein, the Chinese medicine composition is an extract of a first mixture comprising Poria, Polyporus, Rhizoma Alismatis, Atractylodis Rhizoma, Pimenta Officinalis, Zingiberis Rhizoma, Aconiti Lateralis Radix praeparata, Phellodendron amurense, Angelica sinensis, Astragalus Membranaceus, Stephaniae Tetrandrae Radix, Descurainiea Semen, Ephedra Sinica, Armeniacae Semen amarum, Ginseng Radix et Rhizoma, Anredera Cordifolia and Velvet Antler.

The application discloses a content determination method of a traditional Chinese medicine composition containing Ramulus Cinnamomi, and the method comprises the following steps: detecting test sample solution and control sample solution of the traditional Chinese medicine composition; and obtaining content information of the control sample of the traditional Chinese medicine composition according to the detection result; wherein the traditional Chinese medicine composition comprises Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae, Ephedra, Rhizoma Zingiberis Recens, Rhizoma Atractylodis Macrocephalae, Rhizoma Anemarrhenae, Radix Saposhnikoviae and Heishunpian; and the control sample comprises Mangiferin, Paeonoside, Anemonin, 5-O-Methylvisamminol, Cinnamyl Aldehyde, Ammonium Glycyrrhizate and 6-Gingerol. The detection method is simple, accurate and efficient, has good stability, high precision, good reproducibility, is convenient and easy to master, can effectively save energy and reduce analysis cost, and the technical content is not disclosed in the prior art.

The invention relates to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating chronic pulmonary heart disease in the heart failure stage and application of the traditional Chinese medicine composition. 15 g of ginseng; 10 g of herba ephedrae; 15 g of rhizoma belamcandae; 10 g of dried ginger; 5 g of asarum; 15 g of white mulberry root-bark; 30 g of semen lepidii; 30 g of a magnet; 30 g of oyster; 15g of poria with hostwood; 15 g of semen boitae; 15 g of polygala tenuifolia; 15g of schisandra chinensis; the traditional Chinese medicine composition is prepared by the following steps: pretreating the traditional Chinese medicine raw materials, decocting with water twice, and combining filtrate, so that the finally prepared traditional Chinese medicine composition has the effects of tonifying qi and warming yang, tonifying lung and kidney, purging lung and inducing diuresis, reducing phlegm and relieving asthma, and calming heart and tranquilizing, and is suitable for chronic pulmonary heart diseases caused by yang deficiency and water flooding, turbid phlegm obstructing lung and heart and kidney deficiency. The traditional Chinese medicine composition can obviously improve the symptoms of cough and asthma, palpitation, edema, shortness of breath, weakness and restlessness at night, and clinical verification shows that the traditional Chinese medicine composition is definite in curative effect, high in safety and suitable for clinical popularization and application.

This invention relates to the field of traditional Chinese medicine (TCM) technology, and particularly to the application of TCM compositions in the preparation of drugs for the prevention and treatment of asthma. The TCM composition includes Astragalus membranaceus, Eupolyphaga sinensis, Morus alba root bark, Fritillaria cirrhosa, Perilla frutescens seed, Lepidium apetalum seed, Prunus armeniaca seed, Pheretima aspergillum, Ephedra sinica, and Clematis chinensis. Experiments show that the TCM composition provided by this invention can effectively improve airway hyperresponsiveness, reduce lung resistance, and enhance dynamic lung compliance in asthma model animals. Simultaneously, it can significantly reduce the content of pro-inflammatory factors IL-4 and IL-13 in the bronchoalveolar lavage fluid of asthma models, alleviate airway inflammation, and relieve asthma pathological symptoms. It can stably exert its effect in preventing and treating asthma, and its efficacy is stable and its safety is good. It can be further developed into a drug for the prevention and treatment of asthma and has good clinical application prospects.

The invention relates to a method for extracting pinoresinol from herba ephedrae, which can effectively extract pinoresinol from herba ephedrae and realize the application in preparation of medicines for treating pulmonary arterial hypertension, and the preparation method comprises the following steps: taking dried roots and rhizomes of herba ephedrae, and carrying out water extraction and vacuum concentration to obtain an extract; and dispersing with water, eluting, dissolving with methanol, stirring with silica gel, carrying out gradient elution, detecting and identifying, merging the same fractions, loading the target components on column chromatography, eluting, separating and purifying, collecting the fractions with retention time, and drying to obtain the pinoresinol. The pinoresinol prepared by the invention has the effect of resisting abnormal proliferation of pulmonary artery smooth muscle cells (PASMCs), and realizes the application in preparation of medicines for treating pulmonary arterial hypertension. The preparation method is simple, the medicinal value of the pinoresinol and the medicinal value of the herba ephedrae are easily and industrially prepared, the application of the pinoresinol in preparation of the medicine for treating the pulmonary arterial hypertension is realized, and the medicine is a great innovation in preparation of the medicine for treating the pulmonary arterial hypertension and has practical popularization and application values.

This invention discloses a topical traditional Chinese medicine composition for treating pain and its preparation method. The composition includes Evodia rutaecarpa, Cinnamomum cassia, Carthamus tinctorius, Prunus persica, Smilax glabra, Saposhnikovia divaricata, Notopterygium incisum, Angelica pubescens, Boswellia carterii, Commiphora myrrha, Clematis armandii, Paris polyphylla, Ephedra sinica, Zingiber officinale, and Achyranthes bidentata. This invention has the effects of warming the meridians and promoting blood circulation, removing blood stasis, dispelling wind and dampness, reducing swelling and relieving pain. It is a safe, non-invasive, and low-cost external treatment method in traditional Chinese medicine, without burdening the liver and kidneys, and is simple to operate. It can effectively alleviate severe pain in patients with lumbar disc herniation, knee synovitis, rheumatoid arthritis, and late-stage ankylosing spondylitis. It also has rapid analgesic and functional recovery effects, improves symptoms such as insomnia and mobility impairment caused by pain, and improves the quality of life of patients.

This invention provides a traditional Chinese medicine composition for treating squamous cell carcinoma of the lung, its preparation method, and its application, belonging to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition for treating squamous cell carcinoma of the lung provided by this invention comprises the following raw materials in parts by weight: 20-30 parts of Ziziphus jujuba seed, 15-20 parts of ginseng, 10-15 parts of dried ginger, 15-30 parts of stir-fried Atractylodes macrocephala, 40-50 parts of Paeonia lactiflora, 20-30 parts of Rehmannia glutinosa, 15-20 parts of Trichosanthes kirilowii root, 40-50 parts of stir-fried Coix lacryma-jobi, 5-7 parts of honey-processed Ephedra sinica, 20-30 parts of Poria cocos, 5-10 parts of frankincense, 5-10 parts of myrrh, 10-20 parts of Alpinia oxyphylla, 20-30 parts of vinegar-processed tortoise shell, 20-30 parts of vinegar-processed turtle shell, 10-20 parts of Albizia julibrissin bark, and 9-12 parts of prepared licorice root. The aforementioned traditional Chinese medicine composition can effectively improve various clinical symptoms caused by squamous cell carcinoma of the lung, while inhibiting the growth and metastasis of the cancer cells, with significant effects and no side effects.

The application provides a traditional Chinese medicine effective part composition, a preparation method and application thereof. The traditional Chinese medicine effective part composition comprises the following weight parts of effective part medicines of traditional Chinese medicine compound preparation medicines: 125-2000 parts of polysaccharide parts, 0.625-2.5 parts of alkaloid parts, 6.25-100 parts of volatile oil parts and 6.25-100 parts of total glycoside parts. The traditional Chinese medicine compound preparation medicines comprise Poria cocos, Glycyrrhiza uralensis Fisch., Citrus aurantium, Platycodon grandiflorum, Bupleurum smithii, Gypsum fibrosum, Anemarrhena asphodeloides, Peucedanum decursivum, Notopterygium incisum, Cimicifuga foetida, Saposhnikovia divaricata, Schizonepeta, Chuanxiong, Pueraria lobata, Mentha haplocalyx, Lonicera japonica, Forsythia suspensa, Agastache rugosa, Ephedra sinica and Atractylodes lancea. The application further discloses a preparation method of the traditional Chinese medicine effective part composition and application of the traditional Chinese medicine effective part composition in preparing medicines for treating influenza and viral pneumonia. The influenza is influenza A, and the viral pneumonia is pneumonia induced by influenza A virus. A medicine for treating influenza and viral pneumonia comprises the traditional Chinese medicine effective part composition.