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37 results about "Ephedra sinica" patented technology

Ephedra sinica (also known as Chinese ephedra or Ma Huang) is a plant species native to Mongolia, Russia (Buryatiya, Chita, Primorye), and northeastern China (Gansu, Hebei, Heilongjiang, Jilin, Liaoning, Nei Mongol, Ningxia, Shaanxi, Shanxi).

A traditional Chinese medicine composition for treating acute and chronic inflammation of ear, nose and throat and a preparation method thereof

PendingCN122351394AEphedra sinicaMagnolia biondii
A traditional Chinese medicine composition for treating acute and chronic inflammation of the ear, nose, and throat, and its preparation method, characterized in that, by weight, it is made from the following traditional Chinese medicinal materials: 10-30 parts of Lycium chinense root bark, 8-30 parts of Gardenia jasminoides, 10-30 parts of Sanguisorba officinalis root bark, 8-25 parts of Schizonepeta tenuifolia root bark, 6-16 parts of Angelica dahurica root bark, 10-35 parts of Asparagus cochinchinensis root bark, 11-35 parts of Platycodon grandiflorus root bark, 7-46 parts of Paeonia lactiflora root bark, 8-46 parts of Rehmannia glutinosa root bark, and 5-10 parts of Oroxylum indicum root bark. 14 parts of the following ingredients are used: Astragalus membranaceus 12-50 parts, Magnolia biondii 10-30 parts, Trichosanthes kirilowii 10-35 parts, Stellaria dichotoma 5-20 parts, Imperata cylindrica 7-30 parts, Fagopyrum dibotrys 10-35 parts, Coix lacryma-jobi 13-60 parts, Lepidium apetalum 5-15 parts, Gypsum fibrosum 14-50 parts, Sophora tonkinensis 3-20 parts, Lonicera japonica 12-50 parts, Xanthium sibiricum 6-35 parts, Ephedra sinica 6-30 parts, and Styrax benzoin 1-3 parts. After grinding into powder, the mixture is steamed with rice wine to obtain pills. The principle of treating all three (ear, nose, and throat) simultaneously, considering the anatomical structure and physiological function of the ear, nose, and throat, aims to reduce cross-infection, promote recovery, and achieve ideal medicinal properties.
Owner:范昌玖

Application of Traditional Chinese Medicine Compositions in the Preparation of Drugs for the Prevention and Treatment of Lung Injury

PendingCN122321057AReduce lung indexlower levelFritillaria cirrhosaInflammatory factors
This invention relates to the field of traditional Chinese medicine technology, and more particularly to the application of a traditional Chinese medicine composition in the preparation of drugs for the prevention and treatment of lung injury. The traditional Chinese medicine composition includes Astragalus membranaceus, Eupolyphaga sinensis, Morus alba root bark, Fritillaria cirrhosa, Perilla frutescens seed, Lepidium apetalum seed, Prunus armeniaca seed, Pheretima aspergillum, Ephedra sinica, and Clematis chinensis. Experiments show that this traditional Chinese medicine composition can significantly reduce the level of the inflammatory factor TNF-α, decrease the lung index, and alleviate pathological damage to lung tissue, and can be used for the prevention and treatment of lung injury.
Owner:SHIJIAZHUANG YILING PHARMA CO LTD

A hot compress for treating scleroderma and a preparation method thereof

This invention belongs to the technical field of skin disease treatment products, specifically relating to a topical hot compress for treating scleroderma and its preparation method. The topical hot compress for treating scleroderma is made from the following raw materials in parts by weight: 20-40 parts of Artemisia argyi, 20-40 parts of Cinnamomum cassia, 10-20 parts of Sparganium stoloniferum, 10-20 parts of Curcuma zedoaria, 10-20 parts of Loranthus parasiticus, 15-30 parts of Gynostemma pentaphyllum, 10-20 parts of Spirodela polyrhiza, 15-30 parts of Spirodela polyrhiza, 15-30 parts of Ephedra sinica, 20-40 parts of Clematis chinensis, 5-15 parts of Eupolyphaga sinensis, 15-25 parts of Eriocaulon buergerianum, 5-15 parts of Carthamus tinctorius, 3-6 parts of Dracaena cochinchinensis, 3-6 parts of processed Strychnos nux-vomica, 20-40 parts of Vaccaria segetalis, 20-40 parts of Astragalus membranaceus, 10-20 parts of Magnolia officinalis, 10-20 parts of Aconitum carmichaelii, and 22-40 parts of rice wine. This invention is a topical medication that eliminates the need for oral administration, treating the disease externally and guiding the pathogenic factors to a cure. It avoids the inconvenience of bitter medications and effectively relieves symptoms and promotes the cure of localized scleroderma.
Owner:SHAANXI PROVINCIAL HOSPITAL OF CHINESE MEDICINE

Traditional Chinese medicine composition and pharmaceutical preparation for treating chronic obstructive pneumonia

PendingCN121971582Agood treatment effectInhibit the inflammatory responseRespiratory disorderPlant ingredientsEphedra sinicaBelamcanda chinensis
The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for treating chronic obstructive pneumonia and a pharmaceutical preparation. The traditional Chinese medicine composition comprises blackberry lily, honey-fried ephedra, dried ginger, asarum, honey-fried aster, honey-fried tussilago farfara, exocarpium citri rubrum, schisandra chinensis, fried semen raphani, perillaseed, semen brassicae and liquorice. The traditional Chinese medicine composition and the pharmaceutical preparation provided by the invention are used for patients with chronic obstructive pneumonia, can recover the pulmonary ventilation function, effectively inhibit inflammatory response in the body and promote lung tissue injury repair, and have a relatively good treatment effect on chronic obstructive pneumonia.
Owner:BEIJING LANDWANBANG PHARMACEUTICAL TECHNOLOGY CO LTD

Traditional Chinese medicine extract with cold dispelling effect, preparation method thereof and application thereof in preparing medicine for rheumatoid arthritis

ActiveCN119792481BAntipyreticAnalgesicsEphedra sinicaAqueous ethanol
The application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine extract with cold dispelling effect, a preparation method thereof and application of the traditional Chinese medicine extract in preparation of a rheumatoid arthritis medicine. The preparation method comprises the following steps: heating and refluxing guizhi and ginger with water, filtering, obtaining volatile oil, a filtrate and dregs 1; heating and refluxing the filtrate, peony, licorice, ephedra and an ethanol aqueous solution, obtaining extract 2 and dregs 2, and concentrating the extract 2 to obtain extractum 1; heating and refluxing baizhu, zhimu, fangfeng, fried aconite root, the dregs 1, the dregs 2 and solvent 1, obtaining extract 2 and dregs 3, and concentrating the extract 2 to obtain extractum 2; ultrasonic extracting the dregs 3, mixed enzymes and solvent 2, obtaining extract 3, and concentrating the extract 3 to obtain extractum 3; uniformly mixing the volatile oil, the extractum 1, the extractum 2 and the extractum 3 to obtain the traditional Chinese medicine extract; compared with other extraction methods, the traditional Chinese medicine extract prepared by the method has a remarkable cold dispelling effect and rheumatoid arthritis treatment effect.
Owner:SHAANXI PANLONG PHARMACEUTICAL GROUP LIMITED BY SHARE LTD

A traditional Chinese medicine composition for treating cancer pain and numbness, its preparation and application

PendingCN122075613Agood analgesic effectAnti-inflammatoryAntipyreticAnalgesicsEphedra sinicaOpioidergic
This invention relates to the field of traditional Chinese medicine preparation technology, and particularly to a traditional Chinese medicine composition for treating cancer pain and numbness, as well as its preparation and application. This invention designs a traditional Chinese medicine composition for cancer pain and numbness, comprising: *Houttuynia cordata*, *Aconitum carmichaelii*, processed *Aconitum carmichaelii*, centipede, *Astragalus membranaceus*, *Ephedra sinica*, clove, frankincense, ephedra, menthol, and azone. The scientifically formulated combination of principal, assistant, and adjuvant herbs allows for multi-target action on both "cancer pain" (inflammation, compression, nerve infiltration) and "CIPN" (nerve damage), resulting in a superior analgesic effect, while also possessing anti-inflammatory, anti-swelling, potential tumor-suppressing, and nerve-repairing effects. The traditional Chinese medicine composition is prepared into a traditional Chinese medicine ointment, which is administered transdermally, allowing a high concentration of the drug to act directly on the lesion, avoiding the systemic side effects (addiction, constipation, etc.) associated with oral opioids. This is especially suitable for patients who cannot take oral opioids or cannot tolerate them.
Owner:THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV

Zhuang Yao ointment for improving immune disorder of human immunodeficiency virus (HIV) infected person, preparation method of Zhuang Yao ointment and navel patch

PendingCN120939084AAerosol deliveryOintment deliveryEphedra sinicaMedicinal herbs
The invention discloses Yao-strengthening ointment for improving immune disorder of an HIV infected person. The Yao-strengthening ointment is mainly prepared from the following raw materials: astragalus membranaceus, poria cocos, rhizoma cimicifugae, radix achyranthis bidentatae, roasted ephedra, prepared radix aconiti carmichaeli, asarum, roasted liquorice, philippine flemingia root, giantleaf ardisia rhizome, caulis sinomenii, tripterygium wilfordii and gynostemma pentaphylla. The preparation method of the Zhuang Yao ointment comprises the steps of medicinal material treatment, medicinal material extraction and ointment preparation. The whole formula is mainly used for strengthening the body resistance (tonifying qi and warming yang) and eliminating evil (dehumidifying, activating blood and detoxifying), through the compatibility of monarch, minister, assistant and guide, the traditional Chinese medicine aims at core qi deficiency and yang deficiency of immune disorder of HIV infected people and also eliminates pathological products such as dampness, stasis and heat toxin, meanwhile, honey-fried licorice root is used for regulating the medicine property, CD4 cells of the HIV infected people can be improved, immune disorder can be improved to a certain extent, and immune reconstitution is promoted.
Owner:RUIKANG HOSPITAL OF GUANGXI UNIV OF TRADITIONAL CHINESE MEDICINE (GUANGXI INTEGRATED HOSPITAL OF TRADITIONAL CHINESE & WESTERN MEDICINE)

A traditional Chinese medicine composition library based on general and local anesthesia mechanisms, and various dosage forms and preparation methods thereof

PendingCN122499221AEphedra sinicaMedicinal herbs
This invention discloses a library of traditional Chinese medicine (TCM) compositions based on general and local anesthesia mechanisms, along with various dosage forms and preparation methods. The invention constructs a systematic library of TCM anesthetic compositions: the general anesthetic composition consists of extracts from herbs such as Datura stramonium, Datura stramonium, processed Aconitum carmichaelii, processed Aconitum kusnezoffii, Saussurea involucrata, Jasminum sambac root, Rhododendron molle, and Sanqie Sanqie; the local anesthetic composition consists of extracts from herbs such as Asarum heterotropoides, Murraya paniculata, Ephedra sinica, Toad venom, and Corydalis yanhusuo. This invention further develops the above compositions into various modern dosage forms, including injections, tablets, capsules, and sprays. In particular, this invention innovatively introduces a clove-cinnamon natural preservative and flavoring system to replace chemical preservatives. In terms of preparation technology, advanced technologies such as supercritical CO2 extraction, microwave-assisted extraction, nano-embedding, and nanoemulsions are integrated, and a self-extraction scheme is adopted to achieve controllable quality and cost. Simultaneously, a quality detection method based on HPLC fingerprinting is established. This invention achieves full-scenario coverage of anesthesia and analgesia, from general to local, from emergency to routine care, with outstanding advantages of safety, effectiveness, and controllable quality.
Owner:杨伟学

A traditional Chinese medicine composition for treating hashimoto's thyroiditis with depressive symptoms

PendingCN122140878ANervous disorderUnknown materialsMedicinal herbsEphedra sinica
A traditional Chinese medicine composition for treating Hashimoto's thyroiditis comprises the following raw materials in the indicated weight ratios: 50-200 parts Rehmannia glutinosa (processed), 10-60 parts Cinnamomum cassia, 30-100 parts Ephedra sinica, 10-60 parts Cervi cornu slices, 10-60 parts Zingiber officinale (dried), 30-80 parts Glycyrrhiza uralensis (processed), 50-200 parts Paeonia lactiflora (white), 50-200 parts Paeonia veitchii (red), 30-100 parts Paeonia suffruticosa (moutan bark), 50-200 parts Codonopsis pilosula, 50-200 parts Angelica sinensis, 50-200 parts Prunus persica, and 30-100 parts Carthamus tinctorius. The preparation method is as follows: Place Rehmannia glutinosa, Cinnamomum cassia, Ephedra sinica, deer antler slices, dried ginger, prepared licorice root, white peony root, red peony root, peony bark, Codonopsis pilosula, Angelica sinensis, peach kernel, and safflower in a container, add 8 times the total weight of the herbs in cold water, soak for 30 minutes to fully moisten the herbs, bring to a boil over high heat, then simmer over low heat for another 30 minutes; for the second decoction, filter out the liquid from the first decoction, add the remaining herbs and 6 times the total weight of the herbs in warm water, just enough to cover the herbs; soak for 30 minutes, bring to a boil over high heat, then simmer over low heat for another 20 minutes; after the decoction is completed, combine the two decoctions, filter out the dregs, and obtain the traditional Chinese medicine decoction.
Owner:JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE

A Yao medicine bath effervescent tablet compound preparation with anti-rheumatoid arthritis effect and a preparation process thereof

This invention belongs to the field of traditional Chinese medicine preparations, and relates to the preparation method and application of a compound preparation of Yao Yu effervescent tablets with anti-rheumatoid arthritis effect. The compound preparation comprises the following traditional Chinese medicine components: 4 parts by weight of Dioscorea cirrhosa, 3 parts by weight of Tinleaf Vine, 2 parts by weight of Camphor Tree, 2 parts by weight of Rhus chinensis, 3 parts by weight of Rhododendron molle, 1 part by weight of Ephedra sinica, 2 parts by weight of Semi-Acer palmatum, 2 parts by weight of Gynostemma pentaphyllum, and 1 part by weight of Cinnamomum cassia. The preparation steps include: placing Dioscorea cirrhosa, Tinleaf Vine, Camphor Tree, Rhus chinensis, Rhododendron molle, Gynostemma pentaphyllum, Semi-Acer palmatum, Gynostemma pentaphyllum, and Cinnamomum cassia in 6000 parts by weight of 70% ethanol. Extract for 2 hours, repeat three times, filter, and combine the filtrates; concentrate, freeze-dry, pulverize, and pass through an 80-mesh sieve for later use; mix 27.5% freeze-dried powder with 26.45% citric acid, 34.11% sodium bicarbonate, 5.61% PEG6000, and 6.33% lactose evenly, pass through an 80-mesh sieve, and prepare a soft mass using anhydrous ethanol as a wetting agent; pass the soft mass through a 20-mesh sieve and dry at 37℃ for 30 minutes to obtain compound preparation granules; granulate through a 20-mesh sieve for granulation, add lubricant PEG6000 and mix evenly; compress into tablets to obtain compound preparation effervescent tablets. This invention, through pharmacological experiments, confirms that the Yaoyu effervescent tablet compound preparation has a good anti-rheumatoid arthritis effect: it can reduce local inflammatory mediators and serum IL-1β, IL-6, TNF-α, and PEG2 levels, downregulate MDA and increase SOD to improve oxidative stress, inhibit the expression of MMP3, COX-2, and P38 proteins in the synovial membrane, and reduce pathological tissue damage. The medium and high dose groups showed the best effect, and it has a good therapeutic and protective effect on the ankle joint of AA rats, with good clinical application value.
Owner:GUANGXI UNIV OF CHINESE MEDICINE

Method for extracting ephedrine E from herba ephedrae and application of ephedrine E in preparation of medicine for treating pulmonary arterial hypertension

PendingCN121342841AOrganic active ingredientsOrganic chemistryEphedra sinicaEphedrine
The invention relates to a method for extracting ephedrine E from herba ephedrae, which can effectively extract ephedrine E from herba ephedrae and realize application in preparation of medicines for treating pulmonary arterial hypertension. The preparation method comprises the following steps: taking dried roots and rhizomes of ephedra sinica stapf, extracting by adopting a water decoction method, concentrating under reduced pressure to obtain total extract, dispersing with water, eluting, dissolving with methanol, stirring with silica gel, carrying out gradient elution, identifying, merging the same fractions, loading a target component on column chromatography, eluting, purifying, collecting the fractions within retention time, and drying to obtain ephedrine E; the preparation method is simple, the ephedrine E is easy to industrially prepare, the medicinal value of ephedra is expanded, the application in preparation of the medicine for treating the pulmonary arterial hypertension is realized, and the ephedrine E is a great innovation in preparation of the medicine for treating the pulmonary arterial hypertension and has practical popularization and application value.
Owner:HENAN UNIV OF CHINESE MEDICINE

Use of a traditional Chinese medicine composition in the preparation of a drug for ulcerative colitis

PendingCN122321095AEphedra sinicaAreca palm
This invention relates to the application of a traditional Chinese medicine composition in a drug for ulcerative colitis, characterized in that the traditional Chinese medicine composition comprises: 1-100 parts of Magnolia officinalis, 1-100 parts of Areca catechu (roasted), 1-100 parts of Amomum villosum (roasted), 1-100 parts of Ephedra sinica, 1-100 parts of Prunus armeniaca (bitter), 1-100 parts of Notopterygium incisum, 1-100 parts of Zingiber officinale (fresh), 1-100 parts of Pogostemon cablin, 1-100 parts of Eupatorium fortunei, 1-100 parts of Atractylodes lancea, 1-160 parts of Poria cocos, 1-120 parts of Atractylodes macrocephala, 1-100 parts of Gypsum fibrosum, 1-100 parts of Crataegus pinnatifida (roasted), 1-100 parts of Massa fermentata (roasted), 1-100 parts of Hordeum vulgare (roasted), 1-100 parts of Pheretima aspergillum, 1-100 parts of Cynanchum paniculatum, 1-100 parts of Dryopteris crassirhizoma, and 1-100 parts of Lepidium apetalum.
Owner:JIANGSU KANION PHARMA CO LTD

A traditional Chinese medicine composition for treating vaginal itching and a preparation method thereof

The application discloses a traditional Chinese medicine composition for treating vaginitis and a preparation method thereof. The traditional Chinese medicine composition mainly comprises 12 Chinese herbal medicines, i.e. Sophora flavescens, Phellodendron chinense, Dictamnus dasycarpus, Herba Artemisiae Scopariae, Herba Taraxaci, Chrysanthemum indicum, Herba Portulacae, Cnidium monnieri, Angelica polymorpha, Herba Verbena, Herba Menthae and Saposhnikovia divaricata, and further comprises Salix viminalis, Eucalyptus, Ephedra sinica, anthocyanin quaternary ammonium salt, Ocimum basilicum, Houttuynia cordata, polysialic acid, polydopamine, antibacterial polypeptide modified chitosan hydrochloride and artemether. The traditional Chinese medicine composition is prepared by mixing traditional Chinese medicines and bactericidal and bacteriostatic biocompatible materials to prepare various medicaments. The traditional Chinese medicine composition is used for treating pruritus and leukorrhagia caused by endogenous insect poison and burning of yin fluid, and is used for treating bacterial vaginitis, mycotic vaginitis, trichomonal vaginitis and vulvitis. In clinical tests, the traditional Chinese medicine composition has remarkable treatment effect, and the cure rate is more than 95%.
Owner:CHENZHOU TRADITIONAL CHINESE MEDICINE HOSPITAL

External traditional Chinese medicine ointment for treating thyroid nodule as well as preparation method and application of external traditional Chinese medicine ointment

The invention discloses an external traditional Chinese medicine ointment for treating thyroid nodules as well as a preparation method and application thereof, and relates to the field of medicines. The external traditional Chinese medicine ointment comprises traditional Chinese medicine micro powder and a matrix, wherein the traditional Chinese medicine micro powder comprises nidus vespae, dung beetle, cowherb seed, garden balsam seed, ephedra, ground beetle, radix ranunculi ternati, prepared arisaema consanguineum schott, semen momordicae, leech, curcuma zedoary, borneol and selfheal. According to the traditional Chinese medicine micro powder, various insect medicines contain components such as chitinase or enzyme, fiber tissue or cyst can be degraded, targeted knot breaking can be achieved, various plant medicines contain volatile oil or alkaloid components, blood circulation can be improved, and nodule absorption can be promoted. Meanwhile, borneol and ephedra are used for enhancing transdermal absorption of drugs, a matrix promotes drug release, the ointment can directly act on a thyroid nodule focus area, the bioavailability is high, the treatment effect of removing stasis is improved, the burden of liver and kidney is reduced through external administration, skin irritation is small, safety is high, and operation is easy and convenient.
Owner:SHENZHEN BAOAN DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL

A traditional Chinese medicine composite microbial fertilizer for inhibiting angelica root rot

The present invention relates to the technical field of fertilizer preparation, and in particular to a traditional Chinese medicine composite microbial fertilizer for inhibiting angelica root rot. The composite microbial fertilizer for inhibiting angelica root rot provided by the present invention comprises 45-55 parts of composite fertilizer, 20-26 parts of plant ash, 6-10 parts of humic acid, 3-7 parts of diatomaceous earth, 4-8 parts of a composite microbial agent, and 8-12 parts of a traditional Chinese medicine extract. The composite microbial agent comprises Bacillus licheniformis, Bacillus cereus, Bacillus atrophaeus, Pseudomonas chlororaphis, Pseudomonas campestris, Trichoderma viride, and Trichoderma harzianum, with a mass ratio of 14-18:12-16:11-15:8-12:8-12:5-9:5-9, each containing 400-600 million bacteria per gram. The traditional Chinese medicine extract comprises Scutellaria baicalensis, Ephedra sinica, Tagetes erecta, Nerium oleander, Ginkgo biloba, and Sophora flavescens. This fertilizer not only prevents and treats angelica root rot but also significantly improves the yield and quality of angelica, achieving excellent results.
Owner:INST OF SOIL FERTILIZER & WATER SAVING AGRI GANSU ACAD OF AGRI SCI

Method for determining content of aconite alkaloids in traditional Chinese medicine composition containing ramulus cinnamomi and application thereof

The application discloses a method for determining the content of aconite alkaloids in a traditional Chinese medicine composition containing Ramulus Cinnamomi, which comprises the following steps: detecting test sample solution and control sample solution of the traditional Chinese medicine composition, and obtaining the content information of the control sample of the traditional Chinese medicine composition according to the detection result; wherein the traditional Chinese medicine composition comprises Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae, Ephedra, Rhizoma Zingiberis Recens, Rhizoma Atractylodis Macrocephalae, Rhizoma Anemarrhenae, Radix Saposhnikoviae and Heishunpian, and the control sample is benzoyl neoorientaline, benzoyl orientaline, benzoyl hypoorientaline, neoorientaline, hypoorientaline and aconitine. The application carries out the content monitoring research on the monoester type alkaloids of Heishunpian medicinal flavor in the reference sample of the traditional Chinese medicine composition containing Ramulus Cinnamomi, and carries out the limited control research on the diester type alkaloids, and the research on the reference sample of the traditional Chinese medicine composition containing Ramulus Cinnamomi is carried out from the multiple dimensions of safety and effectiveness, and has important quality control significance.
Owner:HUNAN YINENG BIOLOGICAL PHARMA

A traditional Chinese medicine composition for treating chronic eczema and a preparation method thereof

The application discloses a traditional Chinese medicine composition for treating chronic eczema and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: radix astragali 40-80, rhizoma et herba 10-50, raw ginger 5-40, radix glycyrrhizae 5-40, ephedra 5-40, ramulus cinnamomi 10-50, radix scrophulariae 10-40, radix sophorae 10-40, radix alpiniae oxyphyllae 10-50, rhizoma pinelliae 5-40, pericarpium citri reticulatae 5-40, rhizoma chuanxiong 5-40, radix ponicis cum cortex 10-40, fructus corni 5-40, radix gentianae 5-40, radix clematidis 10-40, radix rehmanniae 20-60, radix scrophulariae 10-50, radix paeoniae alba 10-50, cortex mali 5-40, radix et rhizoma 5-40, prepared scrophulariae 5-40, scolopendra 5-40 and rhabdophis 10-50. The traditional Chinese medicine composition can treat chronic eczema by oral administration, and has the advantages of remarkable effect and safety and reliability.
Owner:陆江涛

Application of traditional Chinese medicine composition in preventing influenza A virus replication at cellular level

PendingCN121754633AHydroxy compound active ingredientsAntiviralsEphedra sinicaAreca palm
The invention provides an application of a traditional Chinese medicine composition in preventing influenza A virus replication at a cellular level. The traditional Chinese medicine composition is prepared from the following raw materials: cortex magnoliae officinalis, scorched betel nut, roasted amomum tsao-ko, herba ephedrae, semen armeniacae amarae, notopterygium root, ginger, pogostemon cablin, herba eupatorii, rhizoma atractylodis, bighead atractylodes rhizome, poria cocos, scorched hawthorn fruit, scorched medicated leaven, scorched malt, rhizoma dryopteris crassirhizomae, radix cynanchi paniculati, earthworm, gypsum and semen lepidii. It is confirmed for the first time that the traditional Chinese medicine composition can inhibit replication of influenza A viruses (such as influenza A H1N1 viruses) on the cellular level, has an obvious inhibiting effect on influenza A viruses, has the advantages of being clear in effective component, obvious in drug effect, small in taking dosage and the like, is good in application prospect, is suitable for industrial large-scale production, and has wide application prospects. The traditional Chinese medicine composition can be used for preparing medicines for preventing or treating influenza A virus infection, and has good economic benefits and social benefits.
Owner:STATION OF VIRUS PREVENTION & CONTROL CHINA DISEASES PREVENTION & CONTROL CENT

Method for transforming euphorbia kansui mediated by agrobacterium rhizogenes without tissue culture

PendingCN121555546AOxidoreductasesFermentationBiotechnologyEphedra sinica
The invention relates to the technical field of plant biology, and particularly discloses an agrobacterium rhizogenes-mediated tissue-culture-free euphorbia kansui transformation method, which is technically characterized by comprising the following steps: S1, constructing a pCAMBIA1300:: 35S-EkHMGR-GFP recombinant vector by using a specific primer; s2, establishing a euphorbia kansui regeneration system as an identification basis for obtaining a transgenic plant from an expanded root segment; s3, infecting wounds through agrobacterium rhizogenes K599 to induce hairy roots, and regenerating transgenic plants by utilizing expanded root segments. A set of rapid and stable euphorbia kansui genetic transformation system which is mediated by agrobacterium rhizogenes and does not need tissue culture is established, recombinant plasmids carrying a target gene EkHMGR are introduced into euphorbia kansui by the agrobacterium rhizogenes to obtain transgenic hairy roots, and positive plants obtained by culturing expanded root segments are transplanted. The transformation method constructed by the invention has potential application value on genetic transformation of euphorbia kansui and also has important reference value on genetic transformation of other plants, and research results provide theoretical guidance for promoting synthesis and accumulation of euphorbia kansui key medicinal component euphorbia dienol.
Owner:NORTHWEST UNIV

Traditional Chinese medicine composition and application thereof in preparation of medicine for treating reflux esophagitis

The invention provides a traditional Chinese medicine composition and application thereof in preparation of a medicine for treating reflux esophagitis, and relates to the technical field of traditional Chinese medicine pharmacy. According to the traditional Chinese medicine composition, thunberg fritillary bulb, fructus evodiae and fingered citron serve as monarch drugs, inula flower, buckeye, rhizoma nardostachyos, clove, amomum tsao-ko and membrane of hen egg serve as ministerial drugs, nacre mother of pearl, cortex fraxini, felwort, sweet-scented osmanthus and reed rhizome serve as adjuvant drugs, licorice serves as conductant drugs, and all the drugs are combined to achieve the effects of soothing the liver and harmonizing the stomach, calming the adverse-rising energy, relieving acid and regulating cold and heat. The traditional Chinese medicine composition can significantly improve the esophagitis index of RE rats, has an obvious inhibition effect on inflammatory injury, can significantly improve the pathological morphology of esophageal tissues of the RE rats, and achieves good anti-inflammatory and therapeutic effects on the RE rats. Meanwhile, the traditional Chinese medicine composition can remarkably improve and relieve clinical symptoms such as sour regurgitation, heartburn, abdominal distension and belching of reflux esophagitis patients, and the attack frequency of the clinical symptoms is reduced. The traditional Chinese medicine composition disclosed by the invention is expected to be further developed and popularized as a medicine for treating reflux esophagitis.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Method for treating coronavirus infectious disease and complicated severe coma, ultra-low blood oxygen, moribund disease thereof

ActiveUS12622942B2AntiviralsAluminium/calcium/magnesium active ingredientsEphedra sinicaScutellariae radix
The present invention relates to a method for treating a coronavirus infectious disease and a complication thereof, including: administering a Chinese medicine composition to a subject in need thereof; wherein, the Chinese medicine composition is an extract of a first mixture including Ephedra sinica, Armeniacae Semen amarum, Glycyrrhizae radix et rhizoma, Gypsum fibrosum, Descurainiea semen, stephaniae Tetrandrae radix, Scutellariae radix, Poria, rhizoma alismatis, Polyporus umbellatus, Atractylodis rhizoma, Asteris radix et rhizoma, Tussilago farfara, Pinelliae rhizoma, and Rhei radix et rhizoma.
Owner:TSENG HSUAN-CHING

Traditional Chinese medicine compound preparation for enhancing transdermal absorption and antibacterial activity as well as preparation and application of traditional Chinese medicine compound preparation

PendingCN122005688AAntibacterial agentsAntimycoticsEphedra sinicaCholesterol
The invention belongs to the technical field of medicines, and particularly relates to a traditional Chinese medicine compound preparation for enhancing transdermal absorption and antibacterial activity as well as preparation and application thereof. According to the preparation, on the basis of classic components of patrinia, radix clematidis and ephedra, functional auxiliary materials are added to achieve performance improvement, and the preparation specifically comprises the following raw materials in parts by mass: 20 parts of patrinia, 15 parts of radix clematidis, 15 parts of ephedra, 0.1-0.5 part of a transdermal enhancer, 3-10 parts of a nano-liposome carrier and 0.2-0.8 part of a natural antibacterial synergist. The transdermal enhancer is prepared from menthol, laurocapram and D-limonene; the nano-liposome carrier comprises soybean lecithin, cholesterol and polyethylene glycol. Through the synergistic effect of the nano-liposome carrier, the composite transdermal enhancer and the natural antibacterial synergist, the nano-liposome can be flexibly matched with multiple dosage forms such as lotion, gel, cream and spray, the transdermal absorption of effective components is remarkably improved, the antibacterial spectrum is widened, and the inhibition effect on drug-resistant strains is enhanced.
Owner:GUANGXI YINGKANG PHARMA

Traditional Chinese medicine composition for treating chronic mastitis and preparation method thereof

PendingCN121041403AAntipyreticAnalgesicsEphedra sinicaAngelica dahurica
The invention discloses a traditional Chinese medicine composition for treating chronic mastitis. The traditional Chinese medicine composition is prepared from the following raw material medicines: radix lithospermi, radix rehmanniae preparata, honey-fried ephedra, honey-fried liquorice root, ginger charcoal, fried mustard seed, antler slices, rhizoma phragmitis, vinegar turtle shell and radix angelicae dahuricae. The traditional Chinese medicine composition disclosed by the invention has the effects of warming yang, dispelling cold, removing stasis and diminishing swelling, has a remarkable treatment effect on chronic mastitis, and can effectively promote lump regression and relieve pain. Clinical experiments show that the total effective rate for treating chronic mastitis is 98.00% or above, and the traditional Chinese medicine composition has high popularization and application value.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHEJIANG CHINESE MEDICAL UNIVERSITY

Method for preparing ephedra root phenolic compounds from ephedra root and application thereof

The application relates to a method for preparing ephedra root phenolic compounds from ephedra roots and the application of the ephedra root phenolic compounds, which comprises the following steps: taking dried ephedra roots and rhizomes as raw materials, adding water, decocting and extracting, concentrating to obtain an extract, dispersing the extract in water, washing and eluting, stirring, separating, identifying, loading on a chromatographic column, collecting flow fractions, concentrating and drying, obtaining ephedra root phenol K and ephedra root phenol M; heating and refluxing the ephedra roots to extract, concentrating to obtain an extract, dispersing the extract in water, separating, washing and eluting, identifying and combining, loading on a chromatographic column, collecting flow fractions, concentrating and drying, separating and purifying, obtaining ephedra root phenol I; further separating, loading on a chromatographic column, collecting flow fractions, concentrating and drying, collecting dark spot color bands, eluting, drying and obtaining ephedra root phenol J. The method is easy to operate, the product has high purity, has an anti-depression activity, can be effectively used for preparing medicines for treating depression, expands the medicinal value of the ephedra roots, and has huge economic and social benefits.
Owner:HENAN UNIV OF CHINESE MEDICINE

Topical skin care formulations comprising plant extracts

PendingUS20260000603A1Cosmetic preparationsAntipyreticEphedra sinicaTraditional medicine
A method for treating a person's skin is disclosed. The method can include topically applying to the skin of the person a composition comprising an effective amount of an extract from Ephedra sinica, where the composition reduces oxidative damage to skin, reduces skin inflammation, evens skin tone, or a combination thereof.
Owner:MARY KAY INC

Traditional Chinese medicine nano composition as well as preparation method and application thereof

The invention discloses a traditional Chinese medicine nano composition as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine preparations. The preparation method comprises the following steps: mixing the traditional Chinese medicine raw materials according to the formula ratio, soaking with water, decocting, and filtering with gauze to obtain filtrate; performing differential centrifugation on the filtrate, and taking supernatant; carrying out ultracentrifugation on the supernatant and then taking a precipitate; and resuspending the precipitate with water to obtain the traditional Chinese medicine nano composition. Wherein the traditional Chinese medicine raw materials comprise radix bupleuri, pinellia ternate, codonopsis pilosula, liquorice, scutellaria baicalensis, ginger, jujube, ephedra, cassia twig, radix paeoniae alba, asarum, schisandra chinensis, rhizoma zingiberis, periostracum cicada, stiff silkworm, turmeric, rheum officinale and solidago decurrens. The traditional Chinese medicine nano composition provided by the invention is scientific in compatibility, has the effects of eliminating evil and strengthening the body resistance, not only aims at exterior syndromes of exogenous wind-cold and internal water retention, but also recuperates a shaoyang central machine and reconciles qi activity, realizes the comprehensive curative effects of relieving exterior and interior, regulating cold and heat and treating qi and blood simultaneously, and has remarkable treatment advantages on respiratory tract infectious diseases such as seasonal influenza.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUANGZHOU MEDICAL UNIV (GUANGZHOU RESPIRATORY CENT)

Meridian activating stone needle warming and dredging medicinal oil and preparation method thereof

PendingCN122005726Arun fastRegulate yin and yangDevices for heating/cooling reflex pointsAntipyreticBiotechnologyEphedra sinica
The invention discloses meridian activating stone needle warming and dredging medicinal oil and a preparation method thereof, the meridian activating stone needle warming and dredging medicinal oil comprises medicinal components and natural vegetable oil, and the ratio of the medicinal components to the natural vegetable oil is 1g: 1-5mL; the medicine components comprise the following components in parts by weight: 25-35 parts of processed semen strychni, 40-50 parts of flos carthami, 40-50 parts of ginger processed cortex magnoliae officinalis, 55-65 parts of bran-fried fructus aurantii immaturus, 25-35 parts of processed fructus evodiae, 85-95 parts of raw semen coicis, 25-35 parts of peach kernels, 25-35 parts of radix angelicae sinensis, 25-35 parts of cortex cinnamomi, 10-20 parts of herba ephedrae and 25-35 parts of rhizoma chuanxiong. The cure rate of an intervention group adopting the medicinal oil disclosed by the invention is 42.9%, the total effective rate is 100%, and after intervention, the clinical curative effect and gastrointestinal symptom score of a patient in a test group are obviously superior to those of a control group (Plt; therefore, the medicinal oil combined with stone needle therapy can relieve clinical symptoms of patients, reduce the score of gastrointestinal symptoms and improve the clinical curative effect.
Owner:THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM

A traditional Chinese medicine composition for treating porcine reproductive and respiratory syndrome (PRRS) and its application.

ActiveCN116077578BFood processingAccessory food factorsEphedra sinicaDisease
This invention provides a traditional Chinese medicine composition for treating porcine reproductive and respiratory syndrome (PRRS) and its application. The composition comprises Scutellaria baicalensis, Anemarrhena asphodeloides, Rheum palmatum, Gypsum fibrosum, Houttuynia cordata, Mentha haplocalyx, Atractylodes lancea, Citrus reticulata peel, Poria cocos, Magnolia officinalis, Pueraria lobata, Ligustrum lucidum, Ephedra sinica, Prunus armeniaca, Gynostemma pentaphyllum, Astragalus membranaceus, Psoralea corylifolia, and Glycyrrhiza uralensis. This composition is formulated under the guidance of traditional Chinese veterinary medicine's syndrome differentiation and treatment principles. The combined effects of these herbs are significant in treating PRRS and other damp-heat diseases. Furthermore, this traditional Chinese medicine preparation does not contain antibiotics, is safe and effective, and does not induce drug resistance.
Owner:RIP HI-TECH (TIANJIN) BIOTECHNOLOGY CO LTD

Method for treating pleural effusion

A method for treating pleural effusion includes: administering a Chinese medicine composition to a subject in need thereof; wherein, the Chinese medicine composition is an extract of a first mixture comprising Poria, Polyporus, Rhizoma Alismatis, Atractylodis Rhizoma, Pimenta Officinalis, Zingiberis Rhizoma, Aconiti Lateralis Radix praeparata, Phellodendron amurense, Angelica sinensis, Astragalus Membranaceus, Stephaniae Tetrandrae Radix, Descurainiea Semen, Ephedra Sinica, Armeniacae Semen amarum, Ginseng Radix et Rhizoma, Anredera Cordifolia and Velvet Antler.
Owner:TSENG HSUAN-CHING

Quality control method of traditional Chinese medicine composition containing ramulus cinnamomi and application thereof

ActiveCN119901856BComponent separationEphedra sinicaAnemonin
The application discloses a content determination method of a traditional Chinese medicine composition containing Ramulus Cinnamomi, and the method comprises the following steps: detecting test sample solution and control sample solution of the traditional Chinese medicine composition; and obtaining content information of the control sample of the traditional Chinese medicine composition according to the detection result; wherein the traditional Chinese medicine composition comprises Ramulus Cinnamomi, Radix Paeoniae Alba, Radix Glycyrrhizae, Ephedra, Rhizoma Zingiberis Recens, Rhizoma Atractylodis Macrocephalae, Rhizoma Anemarrhenae, Radix Saposhnikoviae and Heishunpian; and the control sample comprises Mangiferin, Paeonoside, Anemonin, 5-O-Methylvisamminol, Cinnamyl Aldehyde, Ammonium Glycyrrhizate and 6-Gingerol. The detection method is simple, accurate and efficient, has good stability, high precision, good reproducibility, is convenient and easy to master, can effectively save energy and reduce analysis cost, and the technical content is not disclosed in the prior art.
Owner:HUNAN YINENG BIOLOGICAL PHARMA