7 results about "Vaccaria" patented technology

The invention discloses a preparation method and a quality detection method of a fried cowherb seed standard decoction, and relates to the technical field of quality research of traditional Chinese medicinal materials. The preparation method comprises the following steps: weighing a proper amount of fried cowherb seed decoction pieces, putting the decoction pieces into a marmite, decocting twice, adding 8 times of water for soaking for 30 minutes for the first time, boiling with strong fire, and then decocting with slow fire for 30 minutes; adding 6 times of water for the second time, boiling with strong fire, then decocting with slow fire for 20 minutes, filtering the liquid medicine with 200 meshes, cooling the filtrate in a cold water bath, combining the two filtrates, carrying out vacuum concentration at the temperature of 50 DEG C until the weight ratio of the medicinal material to the fluid extract is about 1: 1, collecting the concentrated solution, and freeze-drying to obtain a sample. According to the method, key quality indexes such as the main content, the characteristic chromatogram and the extract of the fried cowherb seeds after the decoction is prepared are measured, the transfer rate is investigated, the component transfer condition from decoction pieces to the decoction is measured through objective quality standards, and the quality degree and effectiveness of the decoction are ensured.

This invention relates to the field of pharmaceutical composition technology, and more particularly to a pharmaceutical composition for treating sepsis and its preparation method. A pharmaceutical composition for treating sepsis is prepared from the following components in parts by weight: 20-26 parts of Andrographis paniculata, 18-24 parts of Forsythia suspensa, 17-21 parts of Anemarrhena asphodeloides, 15-19 parts of Vaccaria segetalis, 14-18 parts of Achyranthes bidentata, 12-16 parts of Scrophularia ningpoensis, 10-14 parts of Coptis chinensis, 7-11 parts of Melia toosendan, 5-9 parts of Prunus persica leaf, and 3-7 parts of Trillium tsao-ko. The formulation of this invention can reduce the inflammatory response of sepsis, alleviate apoptosis of intestinal mucosal epithelial cells in sepsis, promote cell survival, and thereby inhibit organ damage following sepsis.

The invention discloses a preparation method and a quality detection method of a cowherb seed standard decoction, and relates to the technical field of quality research of traditional Chinese medicinal materials. The preparation method comprises the following steps: weighing a proper amount of cowherb seed decoction pieces, putting into a marmite, decocting twice, adding 8 times of water for soaking for 30 minutes for the first time, boiling with strong fire, and decocting with slow fire for 30 minutes; adding 6 times of water for the second time, boiling with strong fire, then decocting with slow fire for 20 minutes, filtering the liquid medicine with 200 meshes, cooling the filtrate to room temperature in a cold water bath, combining the two filtrates, carrying out vacuum concentration at the temperature of 50 DEG C, carrying out vacuum concentration at the absolute vacuum degree of 30-40mbar until the weight ratio of the medicinal material to the fluid extract is about 1: 1, collecting the concentrated solution, and carrying out freeze drying to obtain a sample. According to the method, key quality indexes such as the main content, the characteristic chromatogram and the extract of the cowherb seeds after the decoction is prepared are measured, the transfer rate is investigated, the component transfer condition from decoction pieces to the decoction is measured through objective quality standards, and the quality degree and effectiveness of the decoction are ensured.

This invention provides a topical herbal patch for postpartum acute mastitis and its preparation method, belonging to the field of traditional Chinese medicine pharmaceutical technology. The patch is composed of *Paris polyphylla*, *Vaccaria segetalis*, *Uncaria rhynchophylla*, *Bombyx mori*, *Mild Glauber's salt*, processed *Evodia rutaecarpa*, *Citrus aurantium*, *Cirsium japonicum*, *Smilax china*, *Siegesbeckia orientalis*, stir-fried *Melia azedarach*, and licorice. Based on a rigorous formula of principal, assistant, and adjuvant herbs, this patch significantly reduces serum TNF-α, IL-1β, and IL-6 levels in mice with postpartum mastitis, and significantly improves the overall clinical efficacy. It rapidly relieves core symptoms such as breast redness, swelling, pain, and induration, clears milk stasis, and possesses multiple effects including anti-inflammatory, anti-swelling, lactation-promoting, and analgesic properties. This herbal patch is a topical care preparation that acts directly on the affected area of ​​the breast. The drug is absorbed transdermally without gastrointestinal metabolism, and its components do not affect the infant through breast milk. This provides a safe, efficient, and convenient new topical care solution for postpartum acute mastitis.

This invention discloses a SNP molecular marker related to phosphorus content in *Vaccaria spp.* and its application. The SNP molecular marker consists of SNP1 and SNP2. SNP1 is located at 98,439,964 bp on chromosome 6 of the *Vaccaria spp.* genome, where an A / C base polymorphism exists. SNP2 is located at 98,439,970 bp on chromosome 6 of the *Vaccaria spp.* genome, where a G / C base polymorphism exists. This marker can be used for marker-assisted selection of the high phosphorus trait in *Vaccaria spp.* By detecting the genotype at this locus, the phosphorus content of mature plants can be predicted earlier, thereby significantly shortening the breeding cycle, reducing breeding costs, and improving selection efficiency.

This invention provides a herbal hydrogel eye patch for preventing and treating myopia in adolescents and its preparation method. The patch includes at least a hydrogel layer loaded with herbal extracts. The herbal extracts include the following ingredients: Salvia miltiorrhiza, Angelica sinensis, Lycium barbarum, Buddleja officinalis, Ligusticum chuanxiong, Lonicera japonica, Vaccaria segetalis, Astragalus membranaceus, and Glycyrrhiza uralensis. The matrix of the hydrogel layer includes the following ingredients in parts by weight: poloxamer 20-25 parts, sphingomyelin 2.0-4.0 parts, sodium glycerophosphate 1.5-2.0 parts, sodium phytate 0.5-0.8 parts, modified chitosan 1.0-2.0 parts, and sodium pyrrolidone carboxylate 0.5-1.0 parts. This herbal hydrogel eye patch for preventing and treating myopia in adolescents can improve the discomfort symptoms of myopia patients and effectively prevent and treat myopia in adolescents.

This invention discloses a SNP molecular marker associated with fiber content in *Vaccaria buergeriana* and its application. The SNP molecular marker is located at 203,487,839 bp on chromosome 5 of the *Vaccaria buergeriana* genome, where an A / T base polymorphism exists. This marker can be used for marker-assisted selection of fiber content traits in *Vaccaria buergeriana*. By detecting the genotype at this locus, the fiber content of *Vaccaria buergeriana* plants can be predicted earlier without relying on post-harvest chemical determination, thereby significantly shortening the breeding cycle, reducing breeding costs, and improving selection efficiency.