383 results about "Topical medication" patented technology

I have discovered cosmetic or topical pharmaceutical compositions for external body part or organ slimming, firming, cellulite reduction, fat-reduction, and obesity control benefits that are in synergistic combination with benefits for the treatment of skin aging, skin wrinkles reduction, skin exfoliating, treatment of acne, treatment of rosacea, age-spots reduction, skin surface whitening, skin surface brightening striae distensae (stretch marks) reduction, treatment of pimples, treatment of skin infections and lesions, spider veins reduction, blood microcirculation (venous insufficiency) improvement, UVA/UVB protection of skin, and skin redness reduction. These compositions thus provide multiple combinations of skin and external body part or organ enhancement benefits that can be selective and specific for external body parts and organs such as face, chin, cheeks, arms, "love handles" in abdomen area, eye lids and eye zone, neck, breasts, thighs, and hips. These compositions include a body beneficial composition selected from certain nutraceutical, cosmetic, and pharmaceutical ingredients, a composition to promote collagen and elastin synthesis in the skin, and a cosmetically or pharmaceutically acceptable delivery system.

A wound shield may include a conformable frame to circumscribe a wound. Any suitable dressing may be secured over the conformable frame providing separation between the wound and the dressing. The wound frame may provide pressure relief around a wound or pressure sore to permit healing, allow compression for venous ulcers, retain moisture within the wound environment, absorb exudate, relieve pain and trauma associated with dressing removal, allow debridement and application of topical medications and or other compounds or chemicals, accelerate healing and facilitate monitoring of wounds. A conformable frame may be composed of one or more layers of any suitable material and may include adhesive on one or more surfaces to secure the frame to the wound site, to secure the frame to itself and or any suitable closure element and or to secure the dressing to the conformable frame. A wound shield may be used for humans or any suitable animal.

The biological chitosan-gelatin-polyvinyl alcohol hemostatic dressing is compounded with chitosan, gelatin, polyvinyl alcohol and glycerin, and is prepared into hemostatic cotton, spray and other externally applied medicine forms via conventional production process. The present invention has high adsorption amount, maintained amount, no toxicity, easy absorption by body and high hemostatic function and is superior to available hemostatic dressing.

The topical medicament gel formulation of the present invention includes an anesthetic, an anti-microbial, an oxidant, a nutrient, a diuretic, an opioid, an anti-emetic, an anti-seizure drug, and a non-steroidal anti-inflammatory drug (NSAID), USP in a molecular, as opposed to a salt form, as the active ingredient. Additional constituents illustratively include a skin penetration enhancer and a gelling agent. This invention deals with problems commonly associated with topical application of local medicaments such as: slow onset of action; need for occlusion; and rapid loss of effect due to rapid systemic dispersion. The invention permits enhanced penetration of the medicament and thereby allows for a lesser total dosage of pharmaceutically active ingredient. The use of a lesser total dosage also decreases systemic toxicity.

The present invention is directed to pulverulent mixtures comprising hydrogen peroxide and hydrophobized, pyrogenically prepared silicon dioxide powder, preferably with a methanol wettability of at least 40. The pulverulent mixtures exhibit good storage stability and can be used for the controlled release of hydrogen peroxide and/or oxygen. The invention also includes methods of making these pulverulent mixtures and methods of using the mixtures in detergents, cleaning compositions, topical medications, antimicrobials and other products.

This invention relates to a method of treating otitis externa, and in particular otitis externa of fungal etiology, using topical medication, including antifungal agents such as, for example fluconazole, voriconazole, itraconazole, clotrimazole, amphotericin B, caspofungin (Cancidas®), micafungin (Mycamine®), terbinafine, naftifine, butenafine, amorolfine, ravuconazole, posaconazole, flucytosine, econazole, enilaconazole, miconazole, oxiconazole, saperconazole, sulconazole, terconazole, tioconazole, nikkomycin Z, anidulafungin (LY303366), nystatin, pimaricin, griseofulvin, ciclopirox, haloprogin, tolnaftate, and undecylenate.

A multi-dose, metered dispenser and applicator for topical medications includes inner and outer cylinders and a plurality of expanding bases. These bases form part of a telescopic piston drive system that advances the main piston through the inner cylinder, in accordance with a selected dosage, to dispense a metered amount of the topical medication. The dosage may be selected by a switch located on an outside of the outer cylinder, and dispensed by rotating the inner cylinder relative to the outer cylinder. A tactile and audible feedback mechanism informs the user that the desired dosage of medication has been dispensed.

New topical medicaments are provided. The medicaments comprise menthol and camphor, preferably provided as part of a base gel, supplemented with potassium and a source of oxygen. The most preferred base gel is sold under the name SOMBRA, while the most preferred source of oxygen is a chlorite (e.g., sodium chlorite) and/or spirulina. The medicaments provide high metabolic activities and sustain those activities over prolonged periods of time, thus being useful for treating a large variety of ailments, including diabetic neuropathy, post hepatic neuralgia, scleroderma, psoriasis, strain, spasticity, headaches, neuropathy secondary to drugs, peripheral neuropathy, leg pain, muscle cramps, muscle aches and pains, bruise, sinusitis, sprain, arthritis, joint pain (arthralgia), and edema.

The present invention is a delivery system comprising a pad and a liquid composition, comprising an insoluble dermatologically active ingredient with a viscosity that permits substantially uniform absorption of the composition onto the pad, and the pad is in then packaged in a sealed container.

The invention relates to a compound preparation of an external use pharmaceutical composition for treating swelling and pain, which is a gel binder for treating swelling, and also provides its preparation method. The gel binder is prepared by 20-50% of swelling and pain medicine of the external use pharmaceutical composition for treating swelling and pain as well as proper pharmaceutical excipients. The gel binder for treating swelling is composed of a back lining layer, an ointment-containing body and a cover lining layer. The ointment-containing body, namely the kernel part, is prepared from the swelling and pain medicine, a basic polymer, a cross-linking agent, an organic acid, an excipient, a humectant, an adhesive and the like in certain ratio. The gel binder has the advantages of fast effect, good moisture preservation, high permeability and comfortable use. The product has merits of convenient usage, small irritation on skin and high compliance of patients.

The invention discloses an external-use medicine composition of traditional Mongolian medicines for curing soft tissue injuries, which is prepared from the following medical ingredients in parts by weight: 500-570 of Mongolian sorrel, 500-570 of carthamus tinctorius, 500-700 of pseudo-ginseng, 200-300 of oxytropis myriophylla, 300-450 of terminalia chebula, 200-300 of gypsum, 300-450 of talc powder, 125-188 of borneolum, 160-240 of menthol, 100-150 of camphor, 80-120 of methy salicylate and 0-51 of thymol. In addition, the invention also discloses the preparation method, a quality control method and application of the external-use medicine composition of traditional Mongolian medicines.

Anaphylactic diseases comprising urticaria, papilla, subacute dermatitis, eczema, and the like, are skin diseases which seriously puzzle the human beings. In the invention, antihistamine, zinc salt and weak acid are prepared into a topical compound preparation, which not only reduces the untoward effect of drugs, avoids the first pass effect of the liver when feeding the drugs by mouth, avoids the blood concentration peak valley phenomenon caused by oral feeding, but also can improve the curative effect and is convenient for clinic application. Simultaneously pharmacological tests show that the topical compound preparation obtains excellent drug synergism to the anaphylactic skin diseases and has excellent effects on curing the anaphylactic diseases.

The application describes a convenient portable kit for the application of topical medications. The kit can be used, for example, as a convenient system for application of cold sore medication. The kit includes a container for a quantity of fluid medication sufficient for several treatments together with a plurality of applicators for said medicine. The applicators are specially designed to apply the medicine accurately and with minimal pain.

The invention discloses a soluble microneedle for promoting hair growth. The microneedle comprises a base, a soluble polymer needle body located on the base and a needle tip carrying a hair growth promoting substance. The invention discloses a preparation method of a soluble microneedle for promoting hair growth. The preparation method comprises the following steps: 1) preparing a PDMS microneedlearray mold; 2) preparing a soluble polymer aqueous solution containing substances for promoting hair growth; and 3) preparing the soluble polymer microneedle array loaded with the substance for promoting hair growth, which can solve the technical problems of low transdermal rate, non-uniform distribution, pain in the subcutaneous injection process of interleukin 2, large side effect of a finasteride oral administration mode and high hair transplantation price of the existing external medicine.

The invention discloses new application of arginine, which is the application of arginine or a pharmaceutically acceptable salt, an ester or a mixture of the salt and the ester in preparing topical pharmaceutic preparations with at least one of the following effects: (1) treating and/or facilitating wound healing, and (2) reducing scar formation. Results in pharmacodynamics experiments show that the external use of L-arginine can remarkably facilitate trauma healing of rat skin as well as reduce the area of a wound scar. Arginine not only can be used for treatment and healing of traumas but also can be used for other skin diseases, including a pressure ulcer (bedsore), skin injuries caused by dermatitis, scald, burn and the like.

The invention relates to an external use drug or health product, in particular to an external use drug capable of improving microcirculation, clearing and activating channels and collaterals, promoting blood circulation removing stasis and treating rheumatism bone diseases and a preparation method of the external use drug. The method comprises the steps of taking and cutting the four traditional Chinese medicinal materials of saposhnicovia divaricate, radix angelicae pubescentis, longspur epimedium and caesalpinia sappan into segments with the length ranging from 10 mm to 15 mm, mixing liquidambar formosana hance, rhizoma atractylodis, angelica sinensis, folium artemisiae argyi, suberect spatholobus stems, polygonum cuspidatum, eucommia ulmoides, cassia twig and flos carthami with the four traditional Chinese medicinal materials, placing the mixture into a heat reflux extraction tank, adding water for soaking for 1 h, conducting heating reflux extraction for 5 h, concentrating the mixture to until the density ranges from 1.15 to 1.20, conducting drying at the temperature of 80 DEG C, smashing the mixture into fine powder, placing the fine powder into a granulator for granulation, drying the wet granulates, controlling the temperature to range from 40 DEG C to 50 DEG C for 2 min to 3 min, placing the dried granulates into an oscillating granular to be granulated with a 16-mesh screen cloth, and packaging the granulates to obtain the external use drug. The external use drug has the health care function, improves microcirculation, is applicable to people who have waist, leg, shoulder and neck joint pains caused by rheumatism strains and have microcirculation disturbance caused by hyperostosis.

A chemical compound and a method for its use as a topical medication that can reverse the effects of sun-damage, reverse the signs of aging, demonstrate anti-scarring properties and allow for the treatment of acne while still permitting the patient the ability to simultaneously expose the affected area to the sun without damage that includes a combination of curcumin, water, alcohol, cellulose, anti-inflammatory agent, carbomer, diazolinyl urea, triethanolamine, EDTA and an acidic component that maintains the optimal pH of between 4.5 and 5.5

In some illustrative embodiments, a disposable garment is provided, such as, e.g., a disposable diaper that is combined with a pouch (the terminology pouch is defined herein as encompassing a pocket, a container, an enclosure, a compartment, a housing and/or the like) that contains one or more clean-up wipes and/or other contents (herein referred to as diaper accessories). Preferably, the pouch is substantially moisture-proof (i.e., to retain internal moisture content and/or to inhibit external moisture entry). Preferably, the pouch includes an insulative layer on at least one side to help retain heat within said pouch or pocket. In the preferred embodiments, the pouch operates as a warming pouch. In various embodiments, the pouch can be used to contain a variety of accessories and, most preferably, a variety of diaper accessories, such as, by way of example, wipes, lotions, topical medications and/or powders.

The medicine composition for treating women's pulvic infection is prepared with Chinese medicinal materials rhubarb, tree peony bark, peach kernel and wax gourd seed kernel. The medicine composition may be used in treating acute and chronic women's pulvic infection via oral taking or external application. When applied externally in vagina or rectum, the medicine can reach the affected part directly for fast absorption and high bioavailability while avoid liver's first pass effect. The medicine composition of the present invention is stable and controllable.

The invention relates to an external use Chinese herb preparation, namely, an external use medicine for slimming. The medicine is prepared by over 50 medicines such as cortex acanthopanacis, rheum officinale, radix angelicae pubescentis, asarum and the like. The medicine can be hot compressed at a shenque acupoint, is especially suitable for simple obesity and obesity caused by endocrine dyscrasia, has functions of shaping body, losing weight, and improving endocrine dyscrasia, and has obvious effects according to a survey of over thousand obese patients using the medicine. According to the statistical result of experiment on 500 patients using the medicine, the effect is satisfactory, the cure rate is 93%, and the total effective rate is 100%.

The invention relates to an external medicinal preparation, and particularly relates to an external medicine containing mometasone furoate and a preparation method thereof. In order to achieve the purpose, the invention provides mometasone furoate cream. The mometasone furoate cream is prepared from the following raw materials in parts by weight: 0.5 to 2 parts of mometasone furoate, 75 to 150 parts of an oil phase regulator, 30 to 50 parts of a consistency regulator, 60 to 100 parts of a humectant, 80 to 120 parts of a co-emulsifier, 60 to 90 parts of a co-solvent, 1 to 3 parts of a brightening agent, 30 to 50 parts of an emulsifier, 0.3 to 1 part of a preservative and 500 to 600 parts of water. The mometasone furoate cream prepared by the preparation method disclosed by the invention hasthe advantages of reduced impurity content, increased yield, advanced process, simple method and high yield.

A topical medication garment, a system and a method provide topical medication. An impermeable garment may allow the topical medication to maintain contact with the skin of the user. The garment may prevent the topical medication from absorption into clothing or the undergarment itself. The entirety of the garment may be made from an impermeable material or a portion of the garment may be made from an impermeable material. An impermeable liner may be attached to and/or may be connected to an interior surface of the garment. The garment may have legging portions that reside on the upper thighs of the user when the garment is worn. The legging portions may secure the position of the garment on the user and providing coverage of topical medication applied to the crotch area and upper thighs. The garment may have a structure that resembles a t-shirt.

The invention discloses an externally applied medicine for treating skin disease and application thereof. The medicine consists of an active ingredient and pharmaceutically acceptable auxiliary materials, wherein the active ingredient is a mixture of diflorasone and adapalene, or a mixture of diflorasone and acitretin, or a mixture of diflorasone, adapalene and acitretin. The invention overcomes the defects of poor treatment effect and high side effect of single medication, and the diflorasone and the adapalene or/and the acitretin are compounded to form the compound externally applied medicine. The preparation can be prepared into externally applied formulations in different forms; and due to synergic and complementary effects of medicines, the compound externally applied medicine has high treatment effect, lightens the adverse reaction of the patient in clinical application, has an obvious treatment effect on skin disease, and is easily accepted by the patient.