The invention is applicable to the technical field of medicines, and provides a medication information management system, method and terminal equipment. The medication information management system comprises: a medication knowledge base module which includes basic information of medicines, contents of medicine components, medicine compatibility and other information, a prescription/advices of doctors audit module which is used for auditing outpatient and emergency prescriptions and advices of doctors for hospitalization according to the medication knowledge base module and the basic information, diagnosis information, allergic history information and other information of a patient, and sending the audit result to a drug dispensing system and a liquid mixing system of a pharmacy, and a medication integration module which is used for performing extraction and collection on the past medication information, medication in hospitals, medication for outpatient and discharge medication of thepatient, sorting the extracted and collected information according to the drugs, the usage and dosage and the medication course of treatment, performing medication intervention or medication guidanceon the medication situation of the patient according to the sorting result, and generating a medication instructor. Therefore, the medication information management system, method and terminal equipment can solve the problems of acquisition, utilization, processing and integration of medication information, and can realize effective beforehand intervention for medication.