366 results about "Diglyceride" patented technology

The invention belongs to the technical field of grease chemistry, and particularly relates to diglyceride prepared through enzymolysis and used for reducing blood fat, a preparation method and application of the diglyceride. The preparation method comprises the following steps: (1) mixing edible oil, lipase and water, hydrolyzing and dehydrating to obtain a hydrolysate; and (2) mixing the hydrolysate, glycerol and partial glyceride lipase, reacting, and distilling to obtain the diglyceride, the partial glyceride lipase in the step (2) is a mixture of lipase Lipase G50 and lipase Novozyme 435. The diglyceride prepared by the method disclosed by the invention has an excellent effect of reducing blood fat; and the obtained diglyceride is high in yield and low in acid value, and the finished product does not need deacidification treatment, so that the method is suitable for large-scale industrial production.

The invention relates to a high-yield lipase strain and application thereof, and belongs to the technical field of bioengineering. According to the invention, grease-rich samples from different sources are subjected to enrichment treatment, a strain with lipase activity reaching 80.8 + / -1.8 U / mL is obtained through neutral red grease plate screening, the strain is identified as Burkholderia cepacia OCRI-Lip100 through sequencing and sequence comparison, the Burkholderia cepacia OCRI-Lip100 is named as Burkholderia cepacia OCRI-Lip100, and the Burkholderia cepacia OCRI-Lip100 is preserved in China Center for Type Culture Collection on July 3, 2024 with a preservation number of CCTCC M20241369. Lipase obtained by fermentation of the strain is sequenced, enzymatic properties, catalytic activity and substrate preference of the lipase are studied, the optimum catalytic temperature is 60 DEG C, the specific enzyme activity is higher than that of commercial lipase, the catalytic activity is further improved to 116 + / -0.5 U / mL when a C14 substrate is catalyzed, and triglyceride can be hydrolyzed into diglyceride. The strain provided by the invention and the lipase produced by the strain enrich the resource library of the existing lipase, and provide a basis for improving the industrial application of the lipase and realizing the high utilization rate of resources.

The invention relates to the technical field of food, in particular to diglyceride for reducing triglyceride, cholesterol and uric acid as well as a biological enzyme preparation method and application of the diglyceride. The preparation method comprises the following steps: (1) adding water and glycerol into vegetable oil, and then adding immobilized lipase to react to obtain a reactant; (2) centrifuging reactants, collecting a light-phase product, carrying out molecular distillation, and collecting a heavy-phase product to obtain diglyceride; the immobilized lipase comprises lipase and a carrier, the carrier comprises loofah sponge, soybean meal and bentonite, and the mass ratio of the loofah sponge to the soybean meal to the bentonite is 1: (2-4): (3-6). The method has the advantages that the effects of reducing triglyceride, total cholesterol and uric acid are relatively good, and the yield and the purity are relatively high.

The invention relates to the technical field of grease chemistry, in particular to a preparation method and application of diglyceride oil capable of preventing and treating fatty liver. The preparation method comprises the following steps: (1) mixing raw material oil, water, glycerol and a lipase preparation for catalytic reaction to obtain a product 1; the raw material oil comprises 0.1-8 parts of sea buckthorn seed oil, 0.1-8 parts of acer truncatum seed oil, 60-90 parts of low erucic acid rapeseed oil, 15-35 parts of corn oil and 10-25 parts of peanut oil; the lipase preparation is aspergillus niger lipase and rhizopus niger lipase; (2) performing five-stage molecular distillation on the product 1 to obtain a product 2; and (3) decoloring and deodorizing the product 2 to obtain the product. The diglyceride oil prepared by the invention has excellent effects of preventing and treating fatty liver.

The invention provides a diglyceride oil composition for reducing lactone as well as a product and a preparation method thereof, and relates to the technical field of functional grease processing. The preparation method of the diglyceride oil composition comprises the following steps: (1) mixing corn oil and high oleic acid peanut oil, adding glycerol and water, then adding rhizomucor miehei lipase and pseudomonas onions lipase, and reacting to obtain a material A; (2) mixing sea buckthorn seed oil, acer truncatum seed oil and rapeseed oil, adding glycerol and water, adding candida antarctica lipase B and rhizopus oryzae lipase, and reacting to obtain a material B; and (3) mixing the material A and the material B, heating and centrifuging, taking an upper-layer oil sample, and distilling under a vacuum condition to obtain the diglyceride oil composition. The diglyceride oil composition prepared by the invention has a good effect in the aspect of reducing the internal fat.

An oral pouch product includes a wrapper and a filling material. The wrapper defines a cavity. The filling material is in the cavity. The filling material includes a dry mixture and a liquid mixture. The dry mixture includes a cellulosic material and a water-soluble filler. The liquid mixture includes an oil and liquid nicotine. The oil includes a triglyceride, a diglyceride, a monoglyceride, or any combination thereof. The liquid nicotine is dissolved in the oil. The filling material is free of water or includes water in an amount less than or equal to 5 weight percent.

The invention belongs to the technical field of grease preparation, and particularly relates to a preparation method and application of diglyceride oil with a weight reducing effect. Comprising the following steps: firstly, adding grease into a basic nutrient solution, adding strains for fermentation, and filtering to obtain a glycolysis product; adding glycerol into the glycolysis product, carrying out lipase esterification reaction, and carrying out centrifugal separation to obtain an oil phase; the method comprises the following steps: degrading triglyceride by adopting dominant strain fermentation, then adding glycerol, and carrying out esterification reaction under the action of dominant compound lipase to obtain the diglyceride oil. According to the method, the 1, 3-diglyceride can be selectively generated, the proportion of dominant grease of the 1, 3-diglyceride can be increased, and research shows that the prepared diglyceride oil has good weight reduction and fat reduction effects and has a good application prospect.

The invention discloses a method for preparing uric acid-reducing diglyceride through enzymolysis and a product and application thereof, and belongs to the technical field of diglyceride production, the method comprises the following steps: (1) mixing vegetable oil, glycerol, water and an enzyme preparation for reaction to obtain a reaction solution; (2) standing and layering the reaction liquid, and collecting supernatant; (3) performing distillation separation on the supernatant, and performing decoloration and deodorization to obtain diglyceride; the enzyme preparation in the step (1) is prepared from lipase Lipase, esterase Esterase and phospholipase C in a weight ratio of (5-10): (0.1-0.3): 1. Compared with the prior art, the method disclosed by the invention is simple and low in cost, and the prepared diglyceride has more advantages in the aspect of reducing uric acid.

The present invention provides a method for preparing coffee diglyceride, belonging to the field of biotechnology. The present invention provides a method for preparing coffee diglyceride, comprising the following steps: 1) mixing coffee oil and glycerol, then adding a composite catalyst and choline chloride to fully mix to obtain a mixed solution; 2) subjecting the mixed solution to catalytic reaction, filtration, and molecular distillation in sequence to obtain coffee diglyceride; the catalytic reaction steps include: first vacuum catalysis, first nitrogen bubbling; second vacuum catalysis, second nitrogen bubbling, and adding a composite catalyst; third vacuum catalysis, third nitrogen bubbling; fourth vacuum catalysis, fourth nitrogen bubbling, and adding a composite catalyst; fifth vacuum catalysis, fifth nitrogen bubbling. The above preparation method is simple, low-cost, and the obtained coffee diglyceride has a high yield, high purity, and good flavor.

The invention provides a method for preparing quintuple diglyceride oil for improving blood vessel health through enzymolysis, application and a product, and belongs to the technical field of enzyme engineering. The preparation method comprises the following steps: mixing low-erucic acid rapeseed oil, glycerol, water, fatty acid and lipase, and carrying out enzymolysis reaction, molecular distillation, decoloration and deodorization to obtain diglyceride oil; the lipase is a mixture of Candida antarctica Aspergillus niger lipase, Candida column lipase and bovine pancreas lipase, and the weight ratio of the low-erucic acid rapeseed oil to the glycerin to the water to the fatty acid to the lipase is 500: (80-100): (1-2): (30-60): (10-20). The diglyceride oil prepared by the method can be used for preparing a diglyceride oil composition, and has five functions of reducing blood uric acid, reducing blood total cholesterol, reducing blood triglyceride, reducing blood sugar and increasing blood flow velocity to improve blood vessel health.

The invention relates to the technical field of pharmaceutical preparations, in particular to a docetaxel oral self-microemulsion composition and a preparation process thereof. The docetaxel oral self-microemulsion composition is prepared from docetaxel, an oil phase, a surfactant, a cosurfactant, a stabilizer and an antioxidant, the oil phase is caprylic / capric acid mono / diglyceride, medium chain triglyceride, caprylic acid propylene glycol ester or lauric acid propylene glycol ester. The docetaxel oral self-microemulsion composition provided by the invention has relatively high drug loading capacity, good physical and chemical stability and relatively high bioavailability, and is more suitable for clinical medication.

The invention relates to the technical field of solid beverage food preparation, and discloses instant sugar-controlling and fat-reducing solid milk tea and a preparation method thereof. The formula of the instant solid milk tea capable of controlling sugar and reducing fat comprises the following raw material components in parts by mass: 2-4 parts of tea powder, 10-30 parts of milk powder, 1.8-2.5 parts of freeze-dried ginger powder, 8-15 parts of coconut oil powder, 6-8 parts of linseed diglyceride oil powder, 3-5 parts of stevioside powder and 2-4 parts of freeze-dried fruit powder. The instant sugar-controlling and fat-reducing solid milk tea provided by the invention is strong in solubility, can be quickly dissolved at low temperature without precipitation, is rich in nutrition, savoury and mellow in taste, smooth, fine and smooth without granular sensation and low in calorie, can accelerate fat consumption of an organism and soften blood vessels after being drunk, and has the characteristics of being instant, controlling sugar and reducing fat.

The invention relates to the technical field of weight management, in particular to diglyceride oil powder for weight management and a preparation method of the diglyceride oil powder. The invention discloses diglyceride oil powder for weight management. The diglyceride oil powder comprises the following substances in parts by weight: 18-30 parts of flaxseed diglyceride; 10 to 20 parts of a konjak extract; 3 to 8 parts of L-carnitine; 3-8 parts of a white kidney bean extract; 2-5 parts of a green coffee extract; the flaxseed diglyceride is flaxseed diglyceride in which the sn-1, 3 structure proportion is greater than or equal to 85%. The multi-target body weight regulation network is constructed by taking flaxseed diglyceride as a core and combining the konjak extract, the L-carnitine, the white kidney bean extract and the green coffee extract. And a synergistic effect of'fat-carbon water double blocking + energy consumption 'is formed. The composition breaks through the action limitation of a single component by regulating and controlling full links of intake, absorption and metabolism.

The invention relates to the technical field of diglyceride oil, and discloses a diglyceride-containing grease composition and a preparation method thereof. According to the present invention, a variety of vegetable oils are combined, the combined vegetable oil is subjected to glycerol diesterification, and the turmeric is directly extracted by using the oil after the enzymolysis so as to integrally prepare the curcumin-containing diglyceride oil; according to the present invention, the mass content of diglyceride in the diglyceride oil prepared by combining a plurality of vegetable oils is 40-95%, the mass content of oryzanol is 10000-20000 ppm, the mass content of sterol is 8000-10000 ppm, and the mass content of curcumin is 0.1-0.2%, such that the diglyceride, the oryzanol, the sterol and the curcumin in the diglyceride oil are subjected to a specific content and proportion so as to prevent the color reversion of the oil composition, such that the color reversion of the oil composition can be prevented, and the oil composition can be easily obtained. The grease composition keeps bright appearance and has the advantage of being good in stability.

The invention provides a method for preparing diglyceride oil by a solventless enzymatic method, which comprises the following steps: S1, mixing saturated fatty acid A and saturated fatty acid B to prepare a liquid eutectic mixture; s2, mixing the eutectic mixture, glycerol and lipase in a reaction system, and carrying out esterification reaction to obtain diglyceride; s3, separating the prepared diglyceride, adding the saturated fatty acid A and / or the saturated fatty acid B into the reaction system again to form a liquid eutectic mixture again, and repeating the step 2; wherein in the step S1, the saturated fatty acid A and the saturated fatty acid B are selected from C10-C20 alkanoic acid, in the step S2, the mass ratio of the eutectic mixture to the glycerol is 1: (1-5), and the temperature of the esterification reaction is 35-78 DEG C. The method solves the problem that the high-melting-point saturated fatty acid is difficult to utilize in the existing technology for preparing the diglyceride oil by the solvent-free enzymatic method.

The invention relates to a diacylglycerol acyltransferase capable of synthesizing triglyceride as well as a coding gene and application of the diacylglycerol acyltransferase, and belongs to the field of enzymology, the nucleotide sequence of the gene for coding the diacylglycerol acyltransferase is as shown in SEQ ID NO.1, and the amino acid sequence of the diacylglycerol acyltransferase is as shown in SEQ ID NO.2. The invention also provides a recombinant plasmid and a recombinant engineering bacterium containing the gene of the enzyme. Diglyceride and an acyl donor are used as substrates, and triglyceride is catalytically synthesized through an acyl transfer reaction by using the enzyme. The invention provides an efficient tool for realizing enzymatic biosynthesis and large-scale production of natural triglyceride.

The invention provides diglyceride oil with a blood sugar reducing effect and a preparation method of the diglyceride oil, and relates to the technical field of functional grease processing. The preparation method comprises the following steps: mixing sea buckthorn seed oil, acer truncatum seed oil, rapeseed oil, corn oil and high oleic acid peanut oil, and adding glycerol and water to obtain a material A; adding onion pseudomonas lipase and candida antarctica lipase B into the material A, and carrying out primary reaction to obtain a material B; adding candida lipolytica lipase and candida antarctica lipase B into the material B, and carrying out a second reaction to obtain a material C; adding thermomyces lanuginosus lipase into the material C, and carrying out a third reaction to obtain a material D; and treating the reacted material D to obtain the diglyceride oil. The diglyceride oil prepared by the invention has a good effect in the aspect of reducing blood sugar.

The invention discloses diglyceride prepared by an enzymic method as well as a preparation method and application thereof, and belongs to the technical field of deep processing of grease. The method comprises the following steps: adding fatty acid into a choline chloride-glycerol-urea ternary eutectic solvent, uniformly mixing, and then adding candida antarctica lipase B for esterification reaction to obtain a reaction mixture; separating the reaction mixture, and recovering an upper-layer oil phase; and separating and purifying the upper-layer oil phase to obtain the diglyceride. According to the method, the reaction rate is high, the selectivity of the diglyceride in the esterification process is high, the yield of the diglyceride can reach 65% or above by reacting for 1 h, the selectivity of the diglyceride is 75% or above, and the purity of the separated and purified diglyceride is 90% or above; in addition, the method is simple to operate, and the reaction product and the eutectic solvent can be separated through simple centrifugation after the reaction is finished; in addition, the monoglyceride content in the product is low, and the subsequent separation and purification difficulty is greatly reduced.

The invention belongs to the technical field of functional grease processing, and particularly relates to an enzymolysis preparation method and application of diglyceride with an effect of improving Alzheimer's disease. The method comprises the following steps: mixing low-erucic acid rapeseed oil, glycerol and water, and heating to obtain a pre-reaction mixture; adding compound enzyme for reaction, and then adding candida antarctica lipase B and pseudomonas fluorescens lipase for reaction; and after the reaction is completed, carrying out molecular distillation, collecting a light-phase product, carrying out adsorption filtration, and collecting filtrate to obtain the diglyceride oil. The compound enzyme is composed of rhizomucor miehei lipase, candida rugosa lipase and candida antarctica lipase B in a weight ratio of (2-4): 2: 1. According to the method, the content of diglyceride is effectively increased, the prepared composition has the efficacy of preventing and treating Alzheimer's disease, and the efficacy is shown as improvement of reaction capacity and cognitive function, inhibition of brain apoptosis and acetylcholin esterase, enhancement of SOD and CAT vitality and improvement of related gene expression.

This invention discloses a method for preparing a diglyceride nanostructured lipid carrier hydrogel, comprising the following steps: mixing vegetable oil and diglyceride at a mass ratio of 1:1-3 as phase A; using an aqueous solution of soybean lecithin, tea saponin, and glycerol as phase B; adding phase B to phase A, followed by emulsification, ultrasonic treatment, and finally cooling to room temperature to obtain a diglyceride nanostructured lipid carrier; adding the diglyceride nanostructured lipid carrier to the hydrogel and mixing to obtain the diglyceride nanostructured lipid carrier hydrogel. This invention also discloses the application of the above-mentioned diglyceride nanostructured lipid carrier hydrogel. The diglyceride nanostructured lipid carrier hydrogel of this invention not only has good sun protection, antioxidant, and anti-glycation properties, but can also encapsulate unstable cosmetic raw materials.

The invention belongs to the technical field of food and chemical industry, and particularly relates to a gas-liquid-solid three-phase fluidized bed enzyme reactor and a synchronous preparation method of grease enzyme method deacidification and diglyceride by using the same. According to the method, the gas phase of the three-phase fluidized bed is high-purity dry inert gas, the liquid phase is a uniform solution formed by mixing reaction substrate high-acid-value oil and an acyl acceptor, and the solid phase is immobilized enzyme. The method comprises the following steps: mixing high-acid-value oil and an acyl acceptor to prepare a raw material solution, preheating a feeding tank to a reaction temperature, adding the raw material solution into a gas-liquid-solid three-phase fluidized bed reactor, and carrying out esterification and / or transesterification under the bubbling action of inert gas to realize the deacidification of the high-acid-value oil and the synchronous preparation of the functional lipid. The mixture of the deacidified grease and the functional lipid is obtained. The method has the characteristics of high catalytic efficiency, easiness in separation of the product from enzyme, high nutritional value of the product, no need of adding an organic solvent, difficulty in oxidation of grease and suitability for large-scale production.

The invention relates to the technical field of grease processing, in particular to a grease preparation device and method capable of reducing oil smoke. The device comprises a crude oil preparation device and a crude oil refining device, the crude oil refining device comprises a neutralization tank, a decolorization device and a deodorization device, the neutralization tank comprises a first reaction part and a second reaction part, the first reaction part is provided with a first inlet and a first outlet, the first inlet is provided with a first flow sensor, and the first outlet is provided with a second flow sensor. A vacuum port and a feeding port are formed in the side wall of the first reaction part, the vacuum port is provided with a vacuum valve, the feeding port is provided with a feeding valve, the vacuum port is communicated with a vacuum pump, and the feeding port is communicated with an alkaline material storage tank; crude oil is decompressed through the first reaction part to form bubbles, the bubbles react with an alkaline material in the alkaline material storage tank, and the crude oil flowing out of the first reaction part flows into the second reaction part to be pressurized; and the phosphorus content in the crude oil is reduced, so that the oil smoke generated when the diglyceride oil is used is reduced.

The invention discloses an anti-wrinkle firming face cream based on camellia oleosa seed oil diglyceride and a preparation method of the anti-wrinkle firming face cream. The anti-wrinkle firming face cream is prepared from deionized water, glycerin, butanediol, sodium hyaluronate, camellia oleosa seed oil diglyceride, squalane, simmondsia chinensis seed oil, cetearyl glucoside, glyceryl stearate, acetyl hexapeptide-8, palmitoyl tripeptide-1, vitamin E, 1, 2, 4-trimethyl-1, 3-pentanediol and a proper amount of water. The component A is prepared from 1, 2-hexanediol, caprylyl glycol, a thickening agent and a pH regulator; in the aspect of efficacy, through the synergistic effect of the camellia oleosa seed oil diglyceride, the acetyl hexapeptide-8, the palmitoyl tripeptide-1 and the vitamin E, efficient anti-wrinkle tightening is achieved; in the aspect of skin feeling, squalane and jojoba oil are matched with a light emulsifying system and trace xanthan gum, so that velvet matte texture is made, and the velvet is soft, smooth and not sticky; in the aspect of safety, 1, 2-hexanediol and caprylyl glycol which are safe and free of sensitization are used for corrosion prevention, no irritating component is generated, the anti-allergic skin care lotion is suitable for various skin types, the allergy risk is reduced, and reliable and comfortable skin care experience is brought to consumers.

The present invention provides a method, application and product for preparing diglyceride with weight loss effect by enzymolysis, which belongs to the field of enzyme engineering technology. The method comprises the following steps: S1, mixing lipase, ammonium heptamolybdate tetrahydrate with water, adding glycerol precipitation, filtering, and obtaining an enzyme preparation; S2, mixing plant raw material oil, glycerol, fatty acid, sodium fatty acid with the enzyme preparation obtained in step S1, reacting under inert gas conditions, and obtaining an enzymolysate; S3, molecularly distilling the enzymolysate obtained in step S2 to obtain diglyceride; wherein the lipase is a mixture of Rhizomucor miehei lipase and Candida antarctica Aspergillus niger lipase. The present invention uses ammonium heptamolybdate tetrahydrate to load a specific lipase mixture, and at the same time optimizes the component types and ratios of the raw materials in the enzymolysis process, effectively improving the mass percentage content and diglyceride yield of enzymolysis production of diglyceride.

The invention discloses a composition helpful for maintaining the healthy level of blood sugar. The composition is prepared from the following components in parts by weight: 10-40 parts of diglyceride powder, 15-40 parts of soybean protein isolate, 10-30 parts of xylooligosaccharide, 1-4 parts of mulberry leaf extract, 1-4 parts of radix puerariae extract and 1-4 parts of radix astragali seu hedysari extract. According to the composition disclosed by the invention, a multi-dimensional regulation and control network of metabolic regulation, nutritional supplement and micro-ecological balance can be formed, so that a plurality of components generate a synergistic effect on blood sugar regulation, and the blood sugar regulation capability is remarkably improved.

The invention relates to the technical field of vegetable oil processing, in particular to a diglyceride vegetable oil preparation process capable of reducing the content of 3-chloropropanol ester, which comprises the following steps: adding degummed oil obtained after alkali refining degumming into a short-path distiller, and carrying out primary molecular distillation to obtain crude distilled oil; mixing the crude distilled oil with activated clay, and decolorizing to obtain decolorized oil; pouring the decolored oil into a rotary wiped film type molecular distiller for secondary molecular distillation to obtain a diglyceride vegetable oil semi-finished product; carrying out deodorization treatment on the diglyceride vegetable oil semi-finished product by adopting a double-tower double-temperature sectional deodorization process to obtain deodorized oil; and crystallizing the deodorized oil in a crystallizing tank, growing crystal, filtering and dewaxing to obtain the diglyceride vegetable oil. The diglyceride vegetable oil is prepared by performing molecular distillation twice in the refining process, deodorizing and then performing the dewaxing process, so that the content of 3-chloropropanol ester can be effectively reduced.

The present invention discloses a method for preparing uric acid-lowering diglyceride by enzymatic hydrolysis, as well as its product and application, belonging to the technical field of diglyceride production. The method comprises the following steps: (1) mixing vegetable oil, glycerol, water, and an enzyme preparation to react to obtain a reaction solution; (2) allowing the reaction solution to stand for stratification and collecting the supernatant; (3) distilling and separating the supernatant, decolorizing, and deodorizing the supernatant to obtain diglyceride; the enzyme preparation in step (1) comprises lipase, esterase, and phospholipase C in a weight ratio of 5-10:0.1-0.3:1. Compared with the existing technology, the method of the present invention is simple and low-cost, and the prepared diglyceride has greater advantages in lowering uric acid.

The invention discloses coconut oil rich in diglyceride and a preparation method thereof, and belongs to the technical field of coconut oil deep processing, and the preparation method comprises the following steps: heating coconut oil and monoglyceride as substrates, adding Novozym 435 lipase as a catalyst, and carrying out a catalytic reaction at 40-80 DEG C to obtain the coconut oil rich in diglyceride. The coconut oil and the monoglyceride are used as main raw materials, and the Novozym 435 lipase is selected as a catalyst, so that the conversion efficiency of the diglyceride is improved, the content of the diglyceride in the coconut oil is greatly increased, the nutritional characteristics of the coconut oil are combined with the functional characteristics of the diglyceride, and the nutritional value of the coconut oil is further improved. Meanwhile, the preparation method provided by the invention is mild in reaction condition, low in energy consumption and good in reaction specificity.

The invention discloses an intelligent seasoning control system and method for diglyceride edible oil, and the system comprises a processing data collection module, a cross validation module and a dynamic control module, and is characterized in that the processing data collection module is suitable for collecting data in a stir-frying process in a stir-frying seasoning process; the cross validation module is used for analyzing the aroma release degree in the stir-frying process and the coking degree of seasonings according to data acquired by the processing data acquisition module and carrying out cross validation on the processing process, and the processing data acquisition module is electrically connected with the cross validation module; the dynamic control module is used for dynamically controlling and adjusting the parameters of the stir-frying and seasoning process according to the verification result of the cross verification module, and the dynamic control module is electrically connected with the cross verification module.

An oral pouch product includes a wrapper and a filling material. The wrapper defines a cavity. The filling material is in the cavity. The filling material includes a dry mixture and a liquid mixture. The dry mixture includes a cellulosic material and a water-soluble filler. The liquid mixture includes an oil and liquid nicotine. The oil includes a triglyceride, a diglyceride, a monoglyceride, or any combination thereof. The liquid nicotine is dissolved in the oil. The filling material is free of water or includes water in an amount less than or equal to 5 weight percent.