Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

6 results about "Isoorientin" patented technology

Isoorientin (or homoorientin) is a flavone, a chemical flavonoid-like compound. It is the luteolin-6-C-glucoside. Bioassay-directed fractionation techniques led to isolation of isoorientin as the main hypoglycaemic component in Gentiana olivieri.

Method for removing glycosylation of carbon glycoside by using biological method

The invention discloses a method for performing carbon glycoside deglycosylation by using a biological method. The invention provides application of the protein combination: application in splitting C-C glucosidic bonds; application in preparation of aglycones; the invention also relates to an application in converting glucoside into aglycone. The invention also relates to an application in converting isoorientin and isovitexin into luteolin and apigenin. The invention also relates to an application in converting isoorientin into luteolin. The invention also relates to an application in converting isovitexin into apigenin. Application in splitting C-C glucosidic bonds; the invention also relates to an application in converting mangiferin into mangiferin aglycone. The protein combination comprises an LE1 protein, an LE2 protein and an LE3 protein. The method has great application and popularization values in the production field of aglycones or aglycone derivatives and downstream products thereof.
Owner:MEDICINE & BIOENG INST OF CHINESE ACAD OF MEDICAL SCI

A temperature and pH dual-responsive ophthalmic hydrogel loaded with isoorientin nanomicelles, and a preparation method and application thereof

PendingCN122272472ACorneal permeabilityPharmaceutical technology
This invention belongs to the field of pharmaceutical technology, specifically relating to a temperature- and pH-responsive ocular hydrogel loaded with isosorbide nanomicelles, its preparation method, and its applications. This invention is the first to apply the traditional Chinese medicine ingredient ISO to the treatment of cataracts, and innovatively designs a complete ocular delivery formulation for it. This invention not only pioneers a new application field for ISO in ophthalmic treatment, but more importantly, by constructing a "nanomicelle-smart gel" composite platform, it systematically solves the three fundamental technical challenges faced by ISO in ocular applications: poor solubility, low corneal permeability, and short retention time on the ocular surface, thereby transforming its potential pharmacological activity into actual ocular therapeutic efficacy. Therefore, this invention has significant clinical implications and broad market prospects.
Owner:SHENYANG PHARMA UNIV

Composition containing isoorientin and at least one of 3-o-caffeoylquinic acid and 5-o-caffeoylquinic acid

To provide a novel material derived from natural products that is effective in promoting the expression of the PGC-1α gene or the like.SOLUTION: Provided is a food composition or pharmaceutical composition for promoting expression of the PGC-1α gene in myotube cells or in skeletal muscle, which contains isoorientin and at least one of 3-o-caffeoylquinic acid and 5-o-caffeoylquinic acid.SELECTED DRAWING: Figure 2
Owner:UNIV OF TSUKUBA +1

Application of two small molecular substances in regulation and control of weed suppression activity of flavonoid glycoside substances

PendingCN121713946ABiocideAnimal repellantsOrientinFlavonoid glycosides
The invention discloses application of two small molecular substances in regulation and control of weed suppression activity of flavonoid glycoside substances. The invention provides any one of the following applications of a GST activator and a GST inhibitor: (A1) regulating the inhibition activity of wheat flavone-5-O-glucoside to weeds; and (A2) the inhibition activity of the isoorientin on weeds is regulated. According to the invention, the weed suppression effect of the flavonoid glycoside substances can be obviously improved, and the use of chemical pesticides is reduced, so that a novel biological control method is provided for agricultural production, and green agriculture and sustainable development can be realized.
Owner:ZHONGKENONGFU (BEIJING) BIOTECHNOLOGY CO LTD +1

Method for identifying species of fructus viticis and application

PendingCN121558930AComponent separationVitexinVitexicarpin
The invention relates to the technical field of traditional Chinese medicine detection, in particular to a method for identifying species of fructus viticis and application of the method. When 1.5, the fructus viticis is single-leaf fructus viticis; when the ratio is gt; when 2.0, the fructus viticis is the three-leaf fructus viticis; when the ratio is between 1.5 and 2.0, it is determined that the sample is mixed or abnormal, the content determination method of the isoorientin and vitexin in the indexes is provided in detail, the precision, the stability and the repeatability of the method are good, and the average sample adding recovery rate is 80%-120%; through chemical verification, the identification accuracy reaches 100%, and the index has extremely high specificity on single-leaf fructus viticis; the ratio intervals of the pure single-leaf and three-leaf chastetree fruits are not overlapped, the critical value is clear, and cross misjudgment is avoided, so that the distinguishing degree of the identification index is extremely high, the ratio calculation result is stable, abnormal discrete data is avoided, and the objectivity and reliability of a verification conclusion are ensured.
Owner:甘肃省药品检验研究院

Method for splitting flavonoid C-C glucosidic bond by using enzyme method

The invention discloses a method for splitting a flavonoid C-C glucosidic bond by using an enzyme method. The invention provides application of a protein combination A or a protein combination B, namely application in splitting C-C glucosidic bonds. Application in preparation of aglycones; the invention also relates to an application in converting glucoside into aglycone. The invention also relates to an application in converting isoorientin and isovitexin into luteolin and apigenin. The invention also relates to an application in converting isoorientin into luteolin. The invention also relates to an application in converting isovitexin into apigenin. The protein combination A is an LD1 protein, an LD2 protein and an LD3 protein. And the protein combination B is an LD4 protein, an LD2 protein and an LD3 protein. The method has great application and popularization values in the production field of aglycones or aglycone derivatives and downstream products thereof.
Owner:MEDICINE & BIOENG INST OF CHINESE ACAD OF MEDICAL SCI