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78 results about "Molecular network" patented technology

Large model lightweight reasoning deployment method under limited hardware resources

The invention provides a large model lightweight reasoning deployment method under limited hardware resources, and the method comprises the steps: quantifying the weight importance of a large model through a composite index of gradient sensitivity and activation frequency, and carrying out pruning operation in combination with an improved index weighted moving average strategy, thereby obtaining a structured sparse model; the sparse model is divided into sub-networks by adopting double rules, a routing decision network is trained, and an adaptive feature shunting architecture model is constructed; a multi-precision weight set is generated through a nested quantization technology, quantization bit width is dynamically adjusted, and edge equipment hardware parameters are adapted to complete reasoning environment initialization; after a reasoning request is received, an optimal sub-network is selected based on the trained routing decision network, corresponding weights are loaded in parallel, and a reasoning result is fused and output; and converting a reasoning result format, and dynamically optimizing a scheduling strategy based on a system real-time monitoring index. The method is compatible with a mainstream large model and a hardware platform, and an efficient and universal deployment scheme is provided for end-side AI engineering landing.
Owner:CHENGDU MINGTU TECH CO LTD

Multi-modal characterization molecular property prediction method based on layered bidirectional cross attention

The invention provides a multi-modal characterization molecular property prediction method based on hierarchical bidirectional cross attention, and relates to the technical field of machine learning assisted organic chemistry, and the method comprises the following steps: S10, generating same-molecule multiple sequences for data enhancement; s20, coding the sequence features through a pre-trained molecular language model MolBERT; s30, performing multi-modal feature fusion through a layered bidirectional cross attention mechanism; s40, establishing a prediction head; s50, in the reasoning stage, only the feature extraction and fusion steps are executed, and a molecular property prediction result is output through the trained prediction head. According to the method, the molecular sequence, the topological graph structure and the fingerprint features are effectively integrated, so that the prediction precision of the model on a plurality of MoleculeNet (molecular network benchmark) public data sets is superior to that of an existing method.
Owner:NANTONG UNIV

Analysis method for characteristic chemical components of Qinling Mountain middle-peak honey

The invention belongs to the technical field of honey analysis, and particularly relates to a method for analyzing characteristic chemical components of Qinling Mountain medium-peak honey. The analysis method comprises the following steps: obtaining different extraction layers, and carrying out mass spectrometry on each layer of sample; constructing a molecular network by mass spectrum data through a GNPS platform, and comparing the mass spectrum data with a database to obtain primary identification; unmatched nodes predict the skeleton by using an NAP tool to obtain a secondary result; then fractions are separated, and an unknown structure is deduced by combining an SMART technology with nuclear magnetism; and finally, synthesizing the three types of results to determine the characteristic chemical components of the honey. Compared with a single chromatography-mass spectrometry technology, the analysis method provided by the invention not only realizes data visualization, but also reduces the dependence of chemical component identification on a database to a certain extent, and provides reference for rapid characterization of chemical components in a honey crude extract or fraction.
Owner:NORTHWEST UNIV

Flexible packaging material and preparation method and application thereof

The invention discloses a flexible packaging material and a preparation method and application thereof. The flexible packaging material comprises a sandwich structure formed by sequentially stacking a polymer elastomer with a viscoplastic surface layer, a self-adaptive gas barrier layer and a polymer elastomer with a viscoplastic surface layer, wherein the viscoplastic surface layer of the polymer elastomer consists of a non-polar viscoelastic molecular network and a plastic polar polymer microdomain; the self-adaptive gas barrier layer is at least one of liquid metal, hygroscopic gel and viscous hygroscopic liquid; and the viscoplastic surface layers of the upper and lower polymer elastomers are respectively contacted with two surfaces of the self-adaptive gas barrier layer, so that a sandwich structure is formed. The flexible packaging material not only can be flexibly stretched, but also has ultrahigh gas barrier property, and has important significance and value for promoting the practical application and industrialization process of flexible electronic devices.
Owner:SOUTHERN UNIVERSITY OF SCIENCE AND TECHNOLOGY

Cancer molecular subtype recognition method based on self-adaptive pellet multi-view image clustering

The invention belongs to the technical field of biological information, and particularly relates to a cancer molecular subtype recognition method based on self-adaptive pellet multi-view image clustering. The method comprises the following steps: acquiring a multi-omics data set of cancer molecules, and constructing a pellet set for each kind of omics data in the multi-omics data set; constructing a biological network structure chart according to the particle ball set; fusing the biological network structure diagrams of the omics data to obtain a unified graph; inputting the unified graph into a pre-trained heterogeneous graph neural network for processing to obtain a cancer molecular subtype recognition result; according to the method, multi-scale biological structure features in multiple omics data can be captured at the same time, collaborative optimization of molecular network topology and patient characterization is achieved, and therefore the accuracy of cancer molecular subtype recognition results is improved.
Owner:CHONGQING UNIV OF POSTS & TELECOMM

Low-odor regenerated polypropylene composite material as well as preparation method and application thereof

The invention discloses a low-odor regenerated polypropylene composite material as well as a preparation method and application thereof, and belongs to the technical field of polymer composite materials. Comprising the following raw materials in parts by mass: 10-78 parts of polypropylene, 10-50 parts of regenerated polypropylene, 0-20 parts of an inorganic filler, 2-15 parts of a toughening agent, 0.5-2 parts of an isocyanate coupling agent, 1-3 parts of an odor adsorbent, 0.1-0.5 part of an initiator and 0.5-2 parts of a processing aid. By adding an isocyanate coupling agent, in the extrusion granulation process, an isocyanate group (-NCO) and hydroxyl (-OH) or amino (-NH2) or carboxyl (-COOH)-containing micromolecules remaining in regenerated polypropylene or generated in the extrusion process are subjected to an addition reaction to form urea bonds or urethane bonds, and a plurality of micromolecules are cross-linked to form a macromolecular network; the small molecules with odor are captured, so that the content of emitted substances is reduced; in addition, small molecules are further adsorbed by cooperatively utilizing an odor adsorbent, and the low-emission regenerated polypropylene composite material is prepared.
Owner:ORINKO ADVANCED PLASTICS CO LTD

Picrasma quassioides bitter principle compound in Chinese picrasma quassioides as well as preparation method and application thereof

The invention relates to picrasma quassioides bitter taste element compounds in Chinese picrasma quassioides as well as a preparation method and application thereof, belongs to the technical field of medicines, and particularly relates to 19 picrasma quassioides bitter taste element compounds obtained from branches and leaves of the Chinese picrasma quassioides on the basis of a molecular network annotated with Mzmine and DeepMass from picrasma quassioides which belongs to picrasma quassioides. They structures and configurations are determined by spectral analysis, quantum chemistry calculations, and comparisons of experimental ECD and computational data. In addition, the food refusal activity of all the compounds to plutella xylostella has been assessed, and the food refusal activity of all the compounds to plutella xylostella has been assessed. Wherein part of the compounds show medium antifeedant activity to plutella xylostella. The preparation method is simple and good in reproducibility, and the obtained compound is high in purity.
Owner:SHENYANG PHARMA UNIV

Molecular networks for library molecular structure content

This invention provides a system and program that facilitates the process of generating and / or visualizing molecular networks for library molecular structure content. [Solution] In system 500, the molecular network generation system 502 for library molecular structure content includes an evaluation component 512 that performs a comparison between a first molecular fingerprint including first molecular structure data of a first molecular structure and a second molecular fingerprint including second molecular structure data of a second molecular structure, and a visualization component 516 that generates display data that visualizes a representation of the structural similarity score obtained from the first molecular structure, the second molecular structure and the comparison. The representation by the visualization component includes edges corresponding to the structural similarity score that extend between pairs of nodes corresponding to the first molecular structure and the second molecular structure.
Owner:HIGHCHEM SRO

A PET elastomer, composite material, dynamic covalent network polymer, its preparation method and application

This application relates to the field of polymer materials technology, providing a PET elastomer, composite material, dynamic covalent network polymer, and its preparation method and application. The elastomer is prepared by in-situ self-assembly of crown ether-primary amide dual-functionalized PET through melt blending. Its molecular network integrates a quasi-rotaxane supramolecular crosslinking network. This structure is formed by the host-guest interaction between the crown ether and the primary amide, and can act as a sliding crosslinking point to dissipate energy through the sliding of cyclic components. This application employs a two-step end-capping-in-situ self-assembly process to overcome the technical obstacles of low PET chain-end activity and poor compatibility between polyrotaxane and PET, achieving molecular-level dispersion of quasi-rotaxane in the PET matrix. This fully utilizes the molecular pulley effect to achieve breakthrough toughening of the elastomer. Simultaneously, it combines rigid nanofillers modified with aminosilane coupling agents to form a soft-hard synergistic network, enabling the PET composite material to maintain high toughness while simultaneously improving strength, modulus, and thermal properties.
Owner:WUHAN ZIJIANG ENTERPRISE CO LTD +1

Synergistic drug screening system based on artificial intelligence prediction and metabonomics verification

The invention discloses a drug collaborative screening system based on artificial intelligence prediction and metabonomics verification, and belongs to the technical field of artificial intelligence and bioinformatics crossing. Comprising a multi-source data acquisition and feature fusion module, an artificial intelligence prediction module, a drug screening and visualization module, a metabonomics verification module and a feedback optimization and self-learning module. According to the invention, through multi-modal data integration and feature coding, unified modeling of a drug-disease-molecule network is realized; drug combination synergistic effect prediction is realized through an artificial intelligence algorithm; a prediction result is verified by using non-targeted metabonomics data, and the mechanism interpretability of the model is enhanced; a technical system capable of realizing closed-loop optimization is constructed, and an algorithm and experiment dual-verification platform is provided for drug discovery and precision medicine.
Owner:TIANJIN PEOPLE HOSPITAL +1

Automatic identification method for new pollutants and structural analogues thereof in environment complex sample

The invention discloses a method for automatically identifying new pollutants and structural analogues thereof in environment complex samples, which comprises the following steps of: firstly, analyzing co-occurrence of abundance of substances among samples by using a Pearson's correlation coefficient, and introducing program blank deduction and IQR-Fisher Z transformation abnormal value processing to improve reliability; then, a molecular network is constructed based on high correlation and spectrogram similarity, and cracking products in the source are filtered. Key points are as follows: an iterative annotation strategy is adopted: a candidate structure is obtained from a PubChem database according to m / z of a substance to be annotated, preliminary screening is performed by calculating a Tanimoto coefficient of a Morga fingerprint, or advanced annotation is performed in combination with predicted MS / MS spectrogram fragment matching of a Top-k candidate, and the substance which is successfully annotated is taken as a new round of seed compound, so that automatic recursive expansion of an annotation range is realized. According to the method, the dependence of a traditional method on a standard spectrogram is effectively overcome, and efficient and automatic identification of pollutants with novel structures and analogues thereof is realized.
Owner:SHANGHAI JIAOTONG UNIV

Heat tracing band and preparation method thereof

The invention relates to the technical field of polymer thermoelectric composite materials, in particular to a heat tracing band, which comprises an outer insulating layer, a shielding layer, an inner insulating layer and a conductive core band, and is characterized in that the conductive core band comprises two conductive buses arranged in parallel and a PTC (Positive Temperature Coefficient) composite material coating the conductive buses; the PTC composite material comprises the following components in parts by weight: 180-220 parts of carbon black-carbon fiber composite conductive powder, 600-700 parts of linear low density polyethylene, 50-100 parts of an ethylene-octylene copolymer, 2-4 parts of an antioxidant and 1-3 parts of an ultraviolet light absorber. According to the invention, the ethylene-octene copolymer long-chain branch and the linear low-density polyethylene chain segment are entangled to form a special molecular network; at low temperature, linear low-density polyethylene ensures that the structure is stable, and an ethylene-octylene copolymer flexible chain segment absorbs impact and relieves low-temperature brittleness; at high temperature, the molecular chain of the former is anchored by the long-chain branch of the latter, the sliding of the chain segment is blocked, and a proper amount of balance toughening and heat-resisting agent is added, so that the heat deformation temperature is increased, and the material softening is delayed.
Owner:NINGBO HAISHU TIANYU CABLE CO LTD

Method for distinguishing different base original phellinus igniarius fungi and application

The application discloses a method for distinguishing different base original Phellinus baumii and application. The method comprises the following steps: pretreating Phellinus baumii samples; collecting data in a data-independent mode by using UPLC-Q-TOF-MSE, constructing FBMN and visualizing the collected data, and obtaining a molecular network graph of each Phellinus baumii; collecting data of different base original Phellinus baumii, constructing FBMN and visualizing the data, and obtaining a molecular network graph of the Phellinus baumii samples; and finally comparing the molecular network graph of the Phellinus baumii samples with the molecular network graph of each Phellinus baumii sample, so as to determine whether the Phellinus baumii samples belong to the same base original. The application combines UPLC-Q-TOF-MSE with data-independent mode data collection, realizes FBMN construction of Phellinus baumii and distinction of different base original Phellinus baumii, and can also distinguish the content of specific components in different base original Phellinus baumii, thereby providing a new thought and method for base original identification and component utilization of Phellinus baumii.
Owner:YIXING INST OF FOOD & BIOTECHNOLOGY CO LTD +1

In-situ polymerization low-temperature curing ink-jet ink and application method thereof

The invention discloses in-situ polymerization low-temperature curing ink-jet ink which comprises ink A and ink B. The ink A at least comprises an initiator and deionized water, and the ink B at least comprises a sensitizer, a carbon-carbon double-bond water-soluble monomer, a carbon-carbon double-bond resin water-based dispersion and deionized water. The persulfate initiator in the ink A generates free radicals under the action of the ferrous sulfate sensitizer in the ink B, the free radicals initiate in-situ polymerization reaction to form a polymer network structure, pigment is firmly fixed to the surface of fiber, it is ensured that the initiator and the sensitizer start to react only when making contact, and the color fastness of the pigment is improved. The problem that the ink is unstable in the storage process is solved, and the curing speed is high. According to the invention, the use of an ultraviolet lamp is avoided, and light pollution and ozone pollution generated by the ultraviolet lamp in the environment are reduced. And compared with a UV photoinitiator with aromatic groups, a product obtained by reacting the applied persulfate is safer to a human body, and the method is a more environment-friendly printing scheme.
Owner:HONGSAM DIGITAL SCI & TECH

Analysis method for chemical components in Liujin antipyretic particles

The invention discloses a method for analyzing chemical components in Liujin antipyretic granules, the method is based on an ultra-high performance liquid chromatography-quadrupole time-of-flight tandem mass spectrometry technology, and the method belongs to the technical field of traditional Chinese medicine component analysis and detection. And the mass spectrum response of each chemical component under the determined mass spectrum condition is high. The method comprises the following steps: comparing obtained mass spectrum data with a reference substance, identifying 117 chemical components in total by combining a self-established database and a mass spectrum cracking rule, constructing a feature-based molecular network by utilizing a GNPS platform based on a feature table and MS / MS spectrogram information, and inferring potential compounds through the relevance of structural clusters in the molecular network. The chemical composition of the Liujin antipyretic granules is more comprehensively clarified, and a chemical basis and theoretical support are provided for effective component identification, quality evaluation and pharmacological mechanism research of the Liujin antipyretic granules.
Owner:山东宏济堂制药集团股份有限公司

Probiotics adopting composite gel system and preparation method thereof

The invention relates to the technical field of probiotics, in particular to probiotics adopting a composite gel system and a preparation method of the probiotics, and the probiotics comprise the following components in percentage by mass: 2-6% of an HMPC solution, 8-20% of fructo-oligosaccharide, 5-15% of inulin, 0.2-1.5% of an ionic cross-linking agent, 0.5-1% of silicon dioxide and the balance of probiotic freeze-dried powder. According to the invention, HPMC (hydroxypropyl methyl cellulose), fructo-oligosaccharide, inulin and an ionic cross-linking agent are cooperatively constructed, and HPMC is compounded with fructo-oligosaccharide and inulin, so that a molecular network with different hydrogen bond densities and hydrophilicity can be formed, and a three-dimensional matrix structure of a cellulose-based skeleton, oligosaccharide branched chains and calcium ion cross-linking points is constructed; the compactness and the stability of a gel system in gastric acid are remarkably improved through the dual effects of intramolecular hydrogen bonds and Ca < 2 + > ion bridges in the ionic cross-linking agent.
Owner:BEIJING ANDING HOSPITAL CAPITAL MEDICAL UNIV +1

Method and system for comprehensive detection of neonicotinoids in the environment

The application discloses a comprehensive detection method and system for neonicotinoid compounds in an environment, and is characterized in that: the coverage of mass spectrum information is improved based on coupling of a multi-module data-dependent acquisition mode and a multi-window data-independent acquisition mode; a suspected screening analysis database is established based on a core structure of neonicotinoid compounds; compounds matched with the suspected screening compounds are detected; and the neonicotinoid compounds in the environment sample to be detected are subjected to non-target analysis based on coupling of a feature molecule network technology in the data-dependent acquisition mode and a feature fragment ion extraction technology in the data-independent acquisition mode, so as to back-propagate candidate compounds different from the target compounds and the suspected screening compounds; and the comprehensive detection of potential neonicotinoid compounds in the environment sample to be detected is realized through target analysis, suspected screening analysis and non-target analysis.
Owner:HANGZHOU INST FOR ADVANCED STUDY UCAS

High-strength wear-resistant fc composite material for tarpaulin and preparation method thereof

This invention belongs to the field of polymer functional materials technology, specifically relating to a high-strength and wear-resistant FC composite material for tarpaulins and its preparation method. The FC composite material comprises the following raw materials in parts by weight: 100 parts of 80A resin, 10-15 parts of fluorosilicone rubber, 3-5 parts of cyclosiloxane, 2-4 parts of MQ silicone resin, 1-2 parts of DES, 7 parts of DOA, 8 parts of flame retardant, 5 parts of ultraviolet absorber, and 3-5 parts of color paste. The composite material made with resin, rubber, and cyclosiloxane as the main base materials has better wear and weather resistance than traditional PVC coatings. The cyclosiloxane used will undergo ring-opening to form a polysiloxane long molecular network during the high-temperature curing stage of coating and molding, which improves the tear and scratch resistance of the tarpaulin or inner lining film.
Owner:JIANGSU GAODA NEW MATERIAL CO LTD

Method for constructing coal char macromolecular network model based on hrtem and xps

The present application provides a kind of coal tar macromolecular network model construction method based on HRTEM and XPS, belongs to chemical molecular reaction kinetics technical field, including S1: processing coal tar macromolecular sample HRTEM image data;S2: determine the element composition and functional group composition of coal tar macromolecular sample;S3: set the basic unit structure of coal tar macromolecular network model, and calculate the proportion of different unit structure;S4: construct the aromatic layer sheet of carbon skeleton unit in coal tar macromolecular network model;S5: set the bridge bond of carbon skeleton unit, finally obtain the complete carbon skeleton unit in coal tar macromolecular network model;S6: revise the edge of carbon skeleton unit, hydrogenation is added to carbon skeleton unit and the coal tar macromolecular network model is optimized.It can finely construct coal tar macromolecular network, restore the real composition of coal tar molecule to the greatest extent, ensure that subsequent calculation structure is more real, suitable for constructing macromolecular network model for coal tar obtained under different coal rank and different working conditions.
Owner:DALIAN UNIV OF TECH

The application of alfalfa MsCEPR1 gene and the protein coded by the gene in alfalfa low-phosphorus stress tolerance

The application discloses an application of Medicago sativa MsCEPR1 gene and protein coded by the same in low-phosphorus stress tolerance of Medicago sativa and belongs to the technical field of plant genetic engineering. The Medicago sativa MsCEPR1 gene provided in the application has a nucleotide sequence as shown in SEQ ID NO. 1. The application preliminarily reveals the regulation of CEPR1 on phosphorus absorption related genes by exploring the function of CEPR1 in phosphorus absorption, provides a basis for constructing a molecular network of CEPR1 regulating phosphorus absorption, and provides a direction for cultivating Medicago sativa varieties with high phosphorus absorption, which has important significance for reducing the dependence on phosphorus fertilizer and sustainable agricultural development.
Owner:INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES

Method for interface modification induced uniform prelithiation of silicon-oxygen negative electrode

The application discloses a method for interface modification induced uniform prelithiation of silicon-oxygen negative electrode, and belongs to the technical field of development of lithium ion battery negative electrode. An organic molecule long chain with lithium conduction characteristics is added into deionized water to obtain a mixed solvent by thickening polymerization; a dispersing agent and a conductive agent are added into the mixture, and a molecular network with two-dimensional lithium conduction and conductivity characteristics is prepared by circulating shearing and homogenizing; the two-dimensional molecular network is uniformly mixed with a silicon-oxygen negative electrode, and then homogenizing stirring is carried out, followed by high-temperature solidification, so that a silicon-oxygen material with a lithium conduction and conductivity interface is obtained; the modified silicon-oxygen material is uniformly mixed with a prelithiation reagent, and then high-temperature prelithiation is carried out, so that a uniformly prelithiated silicon-oxygen negative electrode material is obtained after acid washing and sieving. The silicon-oxygen negative electrode material with uniform prelithiation induced by interface modification is obtained by adopting the above steps, the lithium ion battery negative electrode sheet prepared from the material has strong lithium conduction capacity, high peeling strength and low electrode impedance, and a soft package battery cell matched with the positive electrode has excellent capacity retention rate.
Owner:NORTHWESTERN POLYTECHNICAL UNIV

Atgaloxs gene and its application in regulating plant organ size development

This invention belongs to the field of plant breeding and genetic engineering technology, specifically involving AtGalOxs Genes and their application in regulating plant organ size and development. Specifically, this invention screened a gene that regulates plant organ size and development. AtGalOxs It was identified as a key gene regulating the size and development of organs in Arabidopsis thaliana plants, and this was confirmed through cytological observation and transcriptome analysis. AtGalOxs Genes function by regulating cell proliferation and auxin signaling pathways, providing new theoretical basis for elucidating the molecular network regulating plant organ size; AtGalOxs The gene can be directly applied to the regulation of Arabidopsis plant architecture, and its homologous genes are conserved in crops such as Brassicaceae. This provides key gene resources for improving crop plant architecture and increasing yield, which is of great significance for promoting the development of plant molecular breeding technology and improving agricultural production efficiency.
Owner:SHANDONG ACADEMY OF AGRICULTURAL SCIENCES

Process for the production of polyester fibers for automotive interior carpets by drawing

PendingCN122279790APolyesterMolecular network
This invention relates to the field of textile manufacturing technology, specifically to a method for preparing polyester fibers for automotive interior carpets by stretching. The method includes steps such as crosslinking modifier preparation, modified spinning melt formulation, low-temperature orientation stretching, high-temperature reactive stretching, and relaxation heat setting. The method combines polyester chips with a terminal hydroxyl hyperbranched multifunctional polysiloxane crosslinking modifier to covalently anchor flame-retardant and antistatic segments within the polyester macromolecular network. The key technology of this invention lies in the activation of titanium acetylacetonate during the high-temperature stretching stage, which promotes an ester exchange crosslinking reaction between the terminal hydroxyl groups of the modifier and the ester bonds of the polyester molecular chains, constructing chemical crosslinking points in situ under the stretched orientation state. This invention overcomes the defects of traditional physical blending agents, such as stress concentration, high breakage rate, and easy loss of function. By utilizing the orientation-crosslinking structure, it effectively prevents molecular chain slippage under pressure, effectively improving the irreversible deformation problem of carpets under long-term cyclic compression loads, and ensuring the fiber's durable high compression resilience, flame retardant, and antistatic properties.
Owner:SHAANXI DINGCHUAN TEXTILE NEW MATERIAL TECH CO LTD

Super-concise high-toughness damage-repairable nitrile rubber as well as preparation method and application thereof

The invention provides super-concise high-toughness damage-repairable nitrile rubber as well as a preparation method and application thereof, and belongs to the technical field of rubber materials. XNBR is used as a base material, inherent-COOH on an XNBR chain reacts with Zn < 2 + > in ZDMA, a more efficient and more direct ionic crosslinking channel is introduced, Zn < 2 + > of ZDMA is accurately combined on an XNBR molecular chain in advance, it is ensured that a PZDMA chain and an ion cluster are formed more uniformly, a more perfect nanoscale enhanced network is constructed, and then vulcanization is controlled, so that the PZDMA / ZDMA composite material is obtained. And a proper continuous covalent cross-linked network is constructed, so that the mechanical strength can be effectively improved, and the reconstruction constraint on an ion supramolecular network is reduced. And finally, a unique multi-hybrid structure of'covalent cross-linked network + ion cluster physical cross-linked network + grafted PZDMA nanofiber reinforced phase 'is formed in an XNBR matrix, and unification of toughness and repairable performance is realized.
Owner:LANZHOU INSTITUTE OF CHEMICAL PHYSICS CHINESE ACADEMY OF SCIENCES

AtGalOxs gene and application of AtGalOxs gene in regulation and control of size development of plant organs

The invention belongs to the technical field of plant breeding and genetic engineering, and particularly relates to an AtGalOxs gene and application thereof in regulation and control of size development of plant organs. Specifically, a gene AtGalOxs for regulating and controlling the size and development of the plant organs is screened and is clear as a key gene for regulating and controlling the size and development of the plant organs of arabidopsis thaliana, and cytological observation and transcriptome analysis prove that the gene AtGalOxs plays a role by regulating and controlling cell proliferation and auxin signal pathways, so that the gene AtGalOxs can be used for regulating and controlling the size and development of the plant organs of the arabidopsis thaliana. A new theoretical basis is provided for analyzing a molecular network for regulating and controlling the size of the plant organ; the AtGalOxs gene can be directly applied to plant type regulation and control of arabidopsis thaliana, and the homologous gene of the AtGalOxs gene has conservative property in crops such as cruciferae and the like, so that a key gene resource is provided for plant type improvement and yield increase of the crops, and the AtGalOxs gene has important significance in promoting development of a plant molecular breeding technology and realizing improvement of agricultural production benefits.
Owner:SHANDONG ACADEMY OF AGRICULTURAL SCIENCES

Application of brassica napus gene BnaDOF31 in sclerotiniose-resistant breeding of brassica napus

The invention belongs to the field of rape breeding, and particularly discloses an application of a brassica napus gene BnaDOF31 in sclerotiniose resistance breeding of brassica napus, and a protein coded by the BnaDOF31 gene is shown as SEQ ID NO.2. The invention also discloses an application of the BnaDOF31 gene in sclerotiniose resistance breeding of brassica napus. The BnaDOF31 gene of the brassica napus is identified to be capable of regulating the sclerotinia rot resistance of the brassica napus for the first time, a molecular network for regulating the sclerotinia rot resistance of plants is enriched, and the BnaDOF31 gene plays an important role in researching a molecular mechanism formed by the disease resistance of the plants. The overexpression of the BnaDOF31 gene disclosed by the invention obviously reduces the sclerotinia rot resistance of the rape, the plaque area of a knockout strain shows a decreasing trend, the invention provides a new sclerotinia rot resistance negative regulation site of the rape, provides a new target for genetic improvement of disease-resistant rape, and has important significance for guaranteeing high and stable yield of the rape.
Owner:OIL CROPS RES INST CHINESE ACAD OF AGRI SCI

Method for comparing chemical components of different parts of abelmoschus manihot by integrating high-resolution mass spectrum and chemoinformatics

The invention discloses a method for comparing chemical components of different parts of abelmoschus manihot by integrating high-resolution mass spectrometry and chemoinformatics, which comprises the following steps: firstly, optimizing the extraction conditions of different parts of abelmoschus manihot, carrying out ultrasonic extraction, collecting primary and secondary mass spectrometry data by using ultra-high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry, and comparing the primary and secondary mass spectrometry data with the chemical components of different parts of abelmoschus manihot. The method comprises the following steps: performing preliminary identification on compounds through database comparison and standard substance verification, converting mass spectrum data into a standard format, performing peak extraction, alignment and denoising, uploading the mass spectrum data to a GNPS platform, setting a spectrogram similarity threshold value and a minimum matching peak number, constructing a molecular network, realizing clustering and visual analysis of the compounds with similar structures, and finally, determining the quality of the compounds. And carrying out standardization processing on the identified compound list and relative abundance data, generating a heat map by adopting hierarchical clustering analysis, and revealing the similarity and difference of chemical compositions of different parts. According to the method, high-throughput and accurate comparison of chemical components of the abelmoschus manihot is realized, and technical support is provided for quality control of medicinal materials and comprehensive utilization of resources.
Owner:ZHEJIANG UNIV OF TECH +1

A method for preparing an electro-thermal dual-stimulus shape memory composite actuator

The present application relates to the technical field of flexible stimulus-responsive self-driven devices, and particularly relates to a preparation method of an electric-temperature dual-stimulus shape-reversible composite material driver, which comprises the following steps: firstly, chemically modifying and modifying conductor particles and ultrasonically dispersing a solution to improve interface adhesion and improve interface bonding between the conductor and the polymer; secondly, using a double-screw mixing device to melt blend and compound polyvinyl acetate to prepare a shape memory semi-crystalline and carbon-carbon single bond network structure; thirdly, uniformly doping and embedding conductor unit particles into the molecular network to construct a three-dimensional conductive network and form a double-continuous phase structure conductive blend; and finally, hot-pressing the conductive blend to initiate a macromolecular radical crosslinking reaction and prepare an electric-temperature dual-stimulus shape-reversible composite material driver with a conductive-semi-crystalline-crosslinking three-dimensional network structure. The present application can realize electric and thermal dual-stimulus reversible deformation response of the shape memory composite material.
Owner:NANTONG UNIV +1

Preparation method and application of heat-resistant and corrosion-resistant urea modified nickel-based hydroxide ultrathin coating

The invention relates to a preparation method and application of a heat-resistant and corrosion-resistant urea modified nickel-based hydroxide ultrathin coating. According to the method, the urea molecule modified nickel-based hydroxide coating is formed on the surface of the metal material, and the coating has the nucleophilic attack effect of urea molecule carbonyl oxygen and nickel atoms in nickel-based hydroxide and the hydrogen-bond effect of urea molecule amino hydrogen and nickel-based hydroxide hydroxyl oxygen. The stable anchoring between urea and nickel-based hydroxide is formed through the nucleophilic attack effect, and meanwhile, a surface compact molecular network electrostatic field is formed through the hydrogen-bond interaction, so that the penetration of various corrosive ions can be repelled in a coulomb manner, and the coating has good thermal and chemical stability. The method disclosed by the invention is simple to operate, low in energy consumption, easy for large-scale production, suitable for substrates with complex shapes, and capable of being widely applied to industrial scenes needing corrosion-resistant and heat-resistant metal materials, such as ocean engineering, chemical equipment, high-temperature parts and the like, and provides technical support for long-life application of the metal-based materials.
Owner:NANJING UNIV

An intraoral fast melt seamless capsule, manufacturing apparatus and method of preparation

This invention discloses a rapid-dissolving seamless capsule for oral cavity and its preparation method. It comprises an oil-soluble liquid core and a shell encapsulating the core. The shell has a diameter of 4–8 mm, a thickness of 20–200 μm, and the ratio of shell thickness to diameter is strictly controlled within the range of 0.004–0.04. The mass ratio of shell to core is 6:94–35:65. The advantages are: by proposing to strictly control the key structural parameter window of "thickness-diameter ratio" (0.008~0.015), which is much lower than that of conventional microcapsules (usually >0.05), it is the core breakthrough point to achieve the contradiction between "thin-walled and easily broken" and "stable transportation"; by using gelatin with a specific gel strength value (≥150g) as the main film-forming agent, the integrity of the molding can still be maintained under ultra-thin conditions. At the same time, due to its moderate molecular network density, it can be rapidly hydrated and disintegrated in saliva, avoiding the "gelatinization and stickiness" of traditional low-gel strength gelatin or the "insoluble residue" of high-gel strength gelatin.
Owner:JIANGSU UYEA CAPSULE TECH CO LTD