The invention discloses an imidafenacin tablet preparation method. The preparation method comprises the following steps: taking a formulated amount of filler, disintegrant and adhesive, and uniformly mixing to obtain an auxiliary material for later use; dispersing and dissolving a formulated amount of imidafenacin and cosolvent in anhydrous ethanol to obtain a main drug for later use; and uniformly spraying the main drug into the auxiliary material, adding lubricant, uniformly mixing, determining the content of an intermediate compound, and tabletting. According to the imidafenacin tablet preparation method, the main drug is sprayed into the premixed medicinal auxiliary material through a spray gun, thereby well solving the uniformity problem of the tablet under the condition of low drug content. Besides, the low moisture filler is used as the filler of the imidafenacin tablet, so that direct tabletting can be performed without a drying process, and the direct tabletting process is simpler and easier to implement in comparison with wet granulation, fluidized bed, boiling granulation, spray drying and other processes, thereby being suitable for industrial production, being beneficial to product quality control, energy saving and consumption reduction, lowering the production cost, and having favorable practicality.