2390results about How to "Suitable for industrialized mass production" patented technology

The present invention relates to a preparation technique and an application of unsaturated fatty acid microcapsules. The preparation technique of the unsaturated fatty acid microcapsules is characterized in that the present invention includes the following steps: 1) the selection of the raw materials: the inner layer coating materials and the outer layer wall materials are selected for standby according to that the weight ratio of the inner layer coating materials and the outer layer wall materials is 0.7 to 1.5: 3 to 5; the inner layer coating materials are unsaturated fatty acid; the outer layer wall materials are the mixture of any two or more of the natural rubbers, carbohydrates and soluble proteins; 2) the outer layer wall materials are mixed evenly, the weight ratio of the outer layer wall materials and the water is 3 to 4: 6 to 7, the evenly mixed outer layer wall materials are added after the water temperature is increased to 50 DEG C, so as to get the pre-emulsion; 3) the inner layer coating materials are added into the pre-emulsion and is homogenized at the high pressure of 30 to 35MPa, so as to get the emulsion; 4) the emulsion is treated by the spray drying, the materials after the spray drying is cooled by a fluidized bed, the cooling temperature is 30 to 50 DEG C, then the materials pass through a 20 to 60 mesh vibrating screen, so as to get the unsaturated fatty acid microcapsules. The present invention is characterized by water repellency.

The invention relates to a synthesis method of semaglutide. According to the method, a semaglutide product is synthesized by adopting a solid-liquid phase combination method, and three fragments are simultaneously synthesized in a synthesis manner of 16+6+9 fragments, and therefore, the synthesis time of the product is greatly shortened; moreover, by step-by-step analysis on synthesis factors of His-Ala-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly, Gln-Ala-Ala-N6-[N-(17-carboxy-1-oxoheptadecyl-L-gama-glutamyl [2-(2-aminoethoxy) ethoxy] acetyl [2-(2-aminoethoxy) ethoxy] acetyl]-Lys-Glu-Phe, Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH and the like, the difficulty in synthesis of a peptide sequence in solid-phase synthesis is reduced, the problem of batch amplification in the solid-phase synthesis is solved, and the synthesis efficiency is improved; and as liquid-phase fragment synthesis is adopted, the purification difficulty is effectively reduced, and the production cost is greatly lowered. The synthesis method disclosed by the invention has the advantages that the synthesis time can be shortened by 40%, the cost of materials is lowered, the generation quantities of deletion peptide and hybrid peptide are decreased, and the synthesis method is suitable for industrial large-scale production.

The invention discloses a barley noodle, which comprises the following parts: one or more component from barley noodle, wheat flour, maize starch, manihot starch, sweet potato starch, potato starch and glutelin powder, one or more of glutamine transaminase, xylanase and cellulose enzyme, one or more of guar gum, xanthan gum, sodium polyacrylate, sodium alginate and konjaku flour, one or more of monosodium calcium lactate stearate, diacetyl tartaric acid monoester, soya phosphatide and monoaliphatic acid glyceride, water, salt and egg.

The invention discloses a meal replacement protein powder solid beverage for managing the body weight and belongs to the field of nutrient foods. The solid beverage comprises the following components of soybean isolated protein, dried skim milk, whey protein concentrate, resistant dextrin, inulin, L-carnitine, a white kidney bean extract, a guarana extract, soy dietary fiber powder, pea fiber, oat fiber, erythritol, stevioside, phospholipid, Arabic gum, xanthan gum, pectin, alkalized cocoa powder, xylooligosaccharide and edible essence. By comprehensively considering the difference of nutrient components required by a human body at daytime and nighttime, the solid beverage disclosed by the invention is reasonable in formula matching and balanced in nutrition, and is the meal replacement solid beverage for supplementing the nutrients of the human body and controlling the body weight; the production process is simple and the drying is avoided; the damage to plant extracts and other components is prevented, so that the effects of nutrient components are guaranteed; besides, no sugar is added in the formula of the meal replacement protein powder solid beverage, so that the meal replacement protein powder solid beverage is suitable for being eaten by people with diabetes.

The invention relates to a solid dispersion and tablets comprising abiraterone acetate, and preparation methods thereof. The solid dispersion is prepared through the steps that: abiraterone acetate and povidone with a weight ratio of 1:0.5-4 are dissolved in chloroform; and reduced-pressure drying is carried out, such that the solid dispersion is obtained. The tablets comprises 1 part of the abiraterone acetate solid dispersion, 2-8 parts of a filling agent, 0.2-0.8 parts of a disintegrating agent, and 0.05-0.1 parts of a lubricant. According to the invention, a micronization technology and a solid dispersion technology are creatively combined, such that abiraterone acetate water solubility is greatly improved. Therefore, abiraterone acetate can be rapidly dissolved in gastrointestinal tract body fluids.

The invention relates to a porous TiO2 fiber loaded noble metal formaldehyde room-temperature oxidation catalyst and a preparation method thereof. The porous TiO2 fiber loaded noble metal formaldehyde room-temperature oxidation catalyst comprises a porous TiO2 fiber carrier and noble metal active components which are dispersed in the carrier; the porous TiO2 fiber carrier is of a felt shape, and is formed by weaving the TiO2 fibers with the length of a plurality of microns; irregular pores with the pore diameter range of 2-1000nm are formed in the TiO2 fibers so as to form a graduation mesoporous-macroporous structure; and the noble metal exists in a zero valence form with the particle size range of 0.5-3nm. The porous TiO2 fiber loaded noble metal formaldehyde room-temperature oxidation catalyst provided by the invention is of a graduation mesoporous-macroporous structure; the active component noble metal has good dispersibility in the carrier, has the particle size of 1-3nm, and is zero valence; and formaldehyde can be subjected to catalytic decomposition at room temperature, and the catalytic activity is good, and the using quantity is less.

A freeze-dried powder injection of pantorazole sodium is proportionally prepared from pantorazole sodium, excipient, weak-acdic strong-alkaline salt, edathamil disodiumk, and inorganic alkali.

The invention provides a preparation method of graphene oxide. The method comprises the following steps: firstly, mixing graphite, an intercalator and an oxidizing agent under an airtight condition and then carrying out a reaction to obtain a reaction mixture; separating the reaction mixture obtained in the previous step to obtain a reaction product; finally, stripping the reaction product, obtained in the previous step, in a dispersing agent to obtain graphene oxide dispersion liquid. According to the preparation method, the intercalator is inserted into the parts among graphene sheet layers under the action of pressure and under the airtight condition, so that the acting force among layers is reduced, and the distances among the layers are increased; then, the oxidizing agent enters the parts among the graphene sheet layers and has an oxidation reaction, so that the graphene oxide is formed; due to the action of the pressure, the intercalator and the oxidizing agent are enabled to enter the parts among graphene layers more rapidly, and the reaction is promoted to be completed within a short time, so that first-order intercalating for the graphite is realized; furthermore, the preparation method is less in energy consumption in a reaction process, environmentally-friendly, convenient and fast to operate as well as safe and controllable, thus being more suitable for industrial mass production.

The invention relates to the technical field of biodegrade mulching films, in particular to a high-barrier full-biodegrade mulching film and a preparation method thereof. The mulching film is prepared from, by weight, 15-40 parts of PPC, 25-65 parts of PBAT, 10-47 parts of PHBH, 3-10 parts of plasticizer, 3-8 parts of inorganic filler, 0.2-1 part of crosslinking agent, 0.1-1.2 parts of light stabilizer, 0.1-1.2 parts of antioxidant, 0.3-2 parts of lubricant and 0.015-0.08 part of coupling agent, wherein the coupling agent is 0.5-1% of the inorganic filler in weight. The preparation method comprises the steps of filler surface treatment, material drying, mixing, melt extruding for granulation and blow inflation for molding. The PHBH, the PPC and the PBAT in the mulching film are compounded and blended, the components complement each other's advantages, the barrier property is good, the mechanical mechanics performance, use effect and heat preservation and moisturizing properties can meet the requirements of general mulching films, the high-barrier full-biodegrade mulching film can be decomposed completely within 1 year and is simple in preparation process.

The invention discloses a process for preparing acicular, flake nano single crystal magnesia-alumina hydrotalcite Mg6Al2(OH)16C.4H2O, and the prepared Mg6Al2(OH)16CO3.4H2O is used as a flame retardant of power electronic devices. Acicular components comprise 0.06-1.41 mol/L crystal magnesium chloride, 0.02-0.47 mol/L aluminum salt, 0.3-4.5 mol/L sodium hydroxide and 0.094-1.368 mol/L sodium carbonate, and flake components are added with modifier basing on the above components. The invention has the process steps that the crystal magnesium chloride and the sodium hydroxide are firstly dissolved in deionized water and heated and stirred, and then the aluminum salt and sodium carbonate are added into the solution, the deionized water and the sodium hydroxide are added every 20 minutes during reaction, the time of reaction is 0.5-2 hours, and the solution is cooled until room temperature and is washed, filtered and dried. The crystal morphology of the prepared acicular nano single crystal magnesia-alumina hydrotalcite is that the diameter is 10-20 nanometer, the length is 60-130 nanometer, the diameter is 25-80 nanometer, and the length is 200-500 nanometer. The crystal morphology of the flake nano single crystal magnesia-alumina hydrotalcite is that the thickness is 10-20 nanometer, the diameter is 50-100 nanometer, the thickness is 20-30 nanometer, and the diameter is 60-200 nanometer. The process for preparation of the invention has short period and simple process, is prepared at atmospheric pressure, and is suitable for industrial production.

The invention relates to a crop fertilizer, in particular to a refined biological organic fertilizer made by using poultry and livestock excrements and monosodium residues and the preparation method. The refined biological organic fertilizer comprises 30 to 50 percent of poultry and livestock excrements, 20 to 30 percent of monosodium residues, 10 to 30 brown coal, 2 to 8 percent of soybean powder, 2 to 5 percent bone powder, and 1 to 2 percent of rice bran; these components are made into biological organic fertilizers containing the essential nutrients of crops through the functions of a plurality of beneficial microorganism floras. The invention has the advantages of simple preparation method, low cost, no pollution, and can improve the quality of crops, therefore, the invention is an environmental friendly organic fertilizer and suitable for wide popularization.

The invention belongs to the new technical field of a drug preparation and in particular relates to a precursor liposome containing a glycyrrhetinic acid and a method for preparing the same. The precursor liposome containing the glycyrrhetinic acid consists of glycyrrhetinic acid, phospholipids, cholesterol, a surfactant and a water-soluble material; a suspension solution of the glycyrrhetinic acid liposome is prepared by an ethanol injection method or a thin-film dispersion method; and solid liposome powder is prepared by a freeze drying method or a spray drying method. The precursor liposome has simple process and good repeatability, is suitable for industrialized production; through drug administration by intravenous injection, the precursor liposome has long-circulating function, can remarkably reduce the toxicity of drug and achieve the function of prolonging the drug effect; and through oral administration, a solid preparation of the liposome can increase absorption and improve bioavailability by three to five times.

The invention discloses a method for preparing bioactive protein powder through endogenous enzymolysis of marine low-value coarse fish, which is characterized by comprising steps of raw material preparation, primary crushing, enzymolysis, small peptide liquid preparation, mixing and drying, post treatment and the like. During enzymolysis, enzymolysis process parameters are selected according to the endogenous enzyme activity measured from the raw materials; and during mixing and drying, peeled bean pulp powder is used as a carrier to prepare a bioactive protein material. The method of the invention performs process improvement based on the enzymolysis of the primary exogenous proteinase preparation, solves the difficult problems of high production cost, unstable exogenous enzyme activity and non-thorough enzymolysis in the endogenous enzymolysis process, and is more suitable for industrialized production; and the prepared bioactive protein powder has the sense, flavor and cultivation effects superior to those of the fish powder, and is a good fish powder substitute.

The invention discloses a preparation method of an agomelatine I crystal form, which comprises the steps of: adding agomelatine into a mixed solvent of amide and water, heating for dissolving, then reducing the temperature and separating out crystals, and drying to obtain a solid. The agomelatine is dissolved in the heated mixed solvent of the amide and water, and separated out slowly in a cooled mixed solvent of the amide and water, and the high-purity I crystal form can be stably obtained. The method has the advantages of high purity of reaching above 99 percent of the single crystal form, simple operation and good repeatability, and the like and is suitable for industrialized production.

The invention relates to a pantoprazole sodium enteric-coated tablet and a preparation method thereof. The enteric-coated tablet is prepared by a pantoprazole sodium plain tablet which is coated with an insulating layer and an enteric coating layer, and the pantoprazole sodium plain tablet contains 0.5 to 5 percent of silicon dioxide and 0.5 to 5 percent of talcum powder. The method solves the tablet pressing problem of extremely easy sticking during the pressing of the pantoprazole sodium plain tablet.

The invention provides a BiPO4 nanorod and a preparation method and application thereof. The preparation method of the BiPO4 nanorod includes the steps: adding Bi(NO3)3 5H2O and NaH2PO4 2H2O into deionized water for reaction so as to obtain precipitate, namely the BiPO4 nanorod. BiPO4 which is prepared by the method and of monoclinic-phase monazite and hexagonal mixed crystal structures has fine ultraviolet light catalytic activity, and MB (methylene blue) liquid phase degradation rate of the BiPO4 reaches degradation activity of BiPO4 prepared by a hydrothermal method; and the whole preparation method is low in raw material cost, simple in process, low in preparation temperature and suitable for industrialized mass production and has extremely high practical value and application prospect, and product cost is effectively reduced.