The invention discloses a waterborne polyurethane waterproof moisture-permeable coated fabric and a preparation method thereof. The waterborne polyurethane coating is prepared from the following raw materials in parts by weight: 140-150 parts of polyester polyol, 20-24 parts of toluene diisocynate, 40-50 parts of diphenyl-methane-diisocyanate, 8-12 parts of 2,2-dimethylolpropionic acid, 7-9 parts of neopentyl glycol, 3-5 parts of trimethylolpropane, 6-10 parts of dibutyltin dilaurate, 4-6 parts of a DH-1 reinforcing agent, 2-3 parts of an antioxidant TNP, 9-11 parts of an ultraviolet absorbent, 8-12 parts of a dyeing agent, 6-7 parts of liquid paraffin, 4-5 parts of antimony trioxide, 5-7 parts of polytetrahydrofuran dibasic alcohol, 6-8 parts of nanosilicon dioxide, 0.8-1.2 parts of dicumyl peroxide, 7-9 parts of 2,6-Di-tert-butyl-4-methylphenol (BHT), 15-19 parts of deionized water and 7-9 parts of auxiliary. The coated fabric which is high in elongation at break and high in moisture and air permeability is prepared, and the properties such as the elongation at break, the moisture and air permeability, the aging resistance, the flame retardance and the electrostatic resistance of modified polyurethane can be effectively improved.