44 results about "Isophorone" patented technology

The invention discloses an application of rhodococcus diploides in treatment of waste water containing isophorone, the rhodococcus diploides is classified and named as Rhodococcus tectodiphilus, the strain number is GXGD-YZ-2510, and the preservation number is GDMCC No: 67304. The invention further discloses a preparation method of the rhodococcus diploides. The strain shows good growth metabolism activity and isophorone degradation efficiency in a high-salt aerobic environment. Under the conditions that the system salinity is 1 wt%, the initial isophorone concentration is 200 mg / L, and the dissolved oxygen is 3-5 mg / L, the removal rate of the strain on the isophorone reaches 78.6%. The strain not only has excellent salt stress resistance, but also can realize efficient bioconversion of isophorone under high-salt aerobic conditions, and effectively solves the technical bottleneck that isophorone in high-salt wastewater in the industries of petrochemical engineering, chemical engineering, pharmacy and the like is difficult to biochemically treat; the method has the remarkable advantages of being thorough in degradation, low in cost, environmentally friendly, high in process adaptability and the like, and a novel strain resource and an industrialization technical scheme are provided for biological treatment of high-salinity wastewater of refractory organic pollutants.

The application discloses a kind of generation (4S) 4-hydroxyisophorone monooxygenase mutant and preparation method thereof, the monooxygenase is cytochrome P450 BM3 Monooxygenase from bacillus megaterium. The cytochrome P450 BM3 Monooxygenase mutant has high stereoselectivity and high reaction activity to catalyze isophorone hydroxylation, mutant R47L / Y51F / F81W / A191T / N239H / I259V / A276T / A328I / A330S / L353I / I401L / L437LL catalyzes isophorone to obtain (4S) 4-hydroxyisophorone diastereomeric excess rate can reach 95%, yield can reach 96%; the cytochrome P450 BM3 Monooxygenase mutant catalyzes isophorone synthesis (4S) 4-hydroxyisophorone process is simple, environmental protection, and industrialization prospect is good.

Conventionally, CO2 absorbents such as isophorone diamine are used, and the CO2 absorption process at low temperatures and the CO2 extraction process at high temperatures are carried out in separate tanks. However, once the CO2 absorbent such as isophorone diamine absorbs CO2 and solidifies (changes into carbamic acid), it becomes difficult to move it to the other tank, which presents a problem. [Solution] Even when CO2 absorbents such as isophorone diamine absorb CO2 and solidify (change into carbamic acid), the system does not require movement. By creating a (medium to high) vacuum inside the tank, the amount of air inside the tank is reduced, and the concentration of CO2 extracted from the carbamic acid increases accordingly.

The invention discloses a waterproof anti-slip coating for bridges and a production process thereof, and relates to the technical field of protective paints.The coating is composed of a component A and a component B. The component A is a prepolymer generated through reaction of phosphorus-containing modified polycarbonate diol and hexamethylene diisocyanate and has good hydrophobicity, the compactness of a coating is improved, and the anti-slip effect is good; the component B is composed of isophorone diamine, a modified chain extender and a surface modified silicon carbide filler, a silicon dioxide coating layer is formed on the surface of silicon carbide through hydrolytic condensation of tetraethyl orthosilicate, further coupling modification is performed through epoxy-fluorine-containing silane, a reactive epoxy group and a hydrophobic fluorine-containing group are introduced, the skid resistance and the medium infiltration resistance of the filler are improved, and the wear resistance of the filler is improved. Active groups in the modified chain extender promote the formation of a cross-linked structure and improve the mechanical property and bonding strength of the coating, so that the coating has high strength, water resistance, corrosion resistance and excellent skid resistance.

The invention relates to an amine curing agent, thermal viscosity-reducing glue, a thermal viscosity-reducing carrier membrane and a preparation method thereof, the amine curing agent comprises cardanol, isophorone diamine and a furfural solution, the cardanol is melted at the temperature of 50-60 DEG C, then the isophorone diamine is added for reaction at the temperature of 60-70 DEG C, then the furfural solution is added for condensation reaction at the temperature of 75-90 DEG C, and the thermal viscosity-reducing carrier membrane is obtained. And finally, cooling to room temperature to obtain the amine curing agent. The thermal visbreaking carrier film prepared from the amine curing agent and the thermal visbreaking glue not only can provide stable and reliable adhesive force at normal temperature and ensure the stability of process operation, but also can be smoothly peeled off after high-temperature working sections such as cover film pressing and solder resist ink baking, the surface of a PI film is kept clean, and the service life of the PI film is prolonged. The manufacturing efficiency and reliability of the flexible circuit board are obviously improved; the thermal visbreaking carrier film has the advantages of high-temperature visbreaking, no adhesive residue, good dimensional stability and the like.

The application discloses a self-emulsifying polyether amine curing agent and a preparation method and application thereof, and belongs to the field of high polymer materials. According to the application, components A-F are composed of polypropylene glycol or polytetrahydrofuran glycol with a molecular weight range of 800-2000, component B is selected from at least one of isophorone diamine, dicyclohexyl methane diamine or xylylenediamine, component C is at least one of epoxy derivatives containing long-chain alkyl and aromatic ring structures, component D is polyethylene glycol monomethyl ether amine with a polymerization degree range of 2-5 or an amine compound containing a sulfonic acid group, component E is a tertiary amine compound, and component F is at least one of a hindered phenol antioxidant and a phosphite antioxidant. The curing agent is reliably enhanced in reaction activity at normal temperature, the nucleophilic activity of terminal amino groups is significantly improved while excellent water dispersibility is maintained, and thus the curing rate at normal temperature is greatly accelerated.

The invention provides an isophorone dye derivative LYC-CF3 as well as a synthesis method and application thereof. The specific name of the isophorone dye derivative is (E)-4-(2-(3-(dicyanomethylene)-5, 5-dimethylcyclohex-1-ene-1-yl) vinyl)-2-(trifluoromethyl) phenyl trifluoromethanesulfonate, and the structural formula of the isophorone dye derivative is shown in the description. The invention also provides a synthesis method of the derivative LYC-CF3, and a fluorescence imaging experiment of the derivative LYC-CF3 on O2 <-> in PC-12 cells. Through verification of a fluorescence spectrum and a laser confocal microscope, the derivative LYC-CF3 has quick response to O2 <-> in an in-vitro test and cells and relatively remarkable fluorescence imaging capability. Therefore, LYC-CF3 can be used as a fluorescent probe for in-vitro detection of O2 <-> and detection of O2 <-> in cells.

The present invention relates to a continuous process for the liquid-phase synthesis of isophorone by alkaline self-condensation of acetone, comprising the following successive steps:a) continuous injection through a tubular reactor (R) of a stream of an aqueous alkali metal hydroxide solution and of a stream of an organic solution comprising acetone and by-products recycled via step g), followed byb) condensation reaction of acetone within the tubular reactor (R), followed byc) distillation of the reaction mixture obtained from the tubular reactor (R), followed byd) separation of the concentrated crude reaction mixture obtained from the distillation of step c) resulting in an alkaline aqueous phase and an organic phase containing isophorone, followed bye) distillation of the organic phase containing isophorone recovered in the preceding step, followed byf) distillation of the polycondensation by-products from the bottom of the column (D2) obtained from the preceding distillation, followed byg) recycling of the stream obtained from the top of the distillation column (D3) of the preceding step comprising xylitones and / or isoxylitones to the tubular reactor (R).

The application discloses a kind of long-acting high-adhesion, super-slippery function's antifouling anticorrosion integrated coating and its preparation method and application, belong to marine antifouling super-slippery coating material preparation field.The preparation method includes: preparation high-adhesion type epoxy resin precursor, obtain liquid product EGDE-PCA;Preparation high-adhesion, super-slippery integrated epoxy resin precursor, obtain oil liquid product EGDE-PCA / APT-PDMS;EGDE-PCA / APT-PDMS is added to isophorone diamine mixed stirring uniform, coating is carried out on metal material sample, vacuum insulation condition is carried out drying curing reaction, obtains long-acting high-adhesion, super-slippery function's antifouling anticorrosion integrated coating.In early stage of the synthesis reaction, it is not necessary to add organic solvent, and the environmental protection is improved, and the problem that construction process is difficult due to poor fluidity is solved;The coating of the application has super-slippery durability and excellent antifouling anticorrosion effect.

The application provides a high-thermal-conductivity ultraviolet-resistant MiniLED packaging film and a preparation method thereof, and relates to the technical field of packaging film materials.The high-thermal-conductivity ultraviolet-resistant MiniLED packaging film comprises the following raw materials in parts by weight: 60-70 parts of epoxy resin, 9-10 parts of genistein epoxy monomer, 10-12 parts of phosphorus-containing epoxy monomer, 6-7 parts of active diluent, 40-50 parts of functionalized aluminum nitride, and 20-24 parts of isophorone diamine.The high-thermal-conductivity ultraviolet-resistant MiniLED packaging film has excellent flame-retardant, ultraviolet-resistant and thermal-conductivity properties, and solves the problems of flammability, easy aging and poor thermal-conductivity of traditional epoxy resin packaging film materials.

This invention relates to a weather-resistant and anti-aging coating for coastal port cranes and its preparation method, belonging to the field of coating materials technology. The coating comprises component A and component B; component A includes an isocyanate-terminated prepolymer, a tri(dibenzoylmethane) ytterbium(III) complex, a spiropyran derivative, and additives; component B is obtained by dissolving isophorone diamine and 2,2'-diaminodiphenyl disulfide in ethyl acetate solvent, with a solid content of 40-60 wt%, and a molar ratio of isophorone diamine to 2,2'-diaminodiphenyl disulfide of (1-4):1; the molar ratio of isocyanate groups in component A to imino groups in component B is (1-1.05):1. This invention accelerates the exchange of dynamic disulfide bonds by constructing a photothermal conversion system, thereby enhancing the coating's ability to dissipate mechanical stress under ultraviolet light irradiation and simultaneously imparting long-term weather resistance to the coating.

The invention discloses a polymer-based pipeline wear-resistant and low-temperature-resistant coating material and a preparation method thereof in the field of polymer materials. The material is prepared from polyamide, dynamic lipoic acid network modified polyurethane urea, a liquid crystal benzoxazole polysiloxane alternating copolymer, silicon carbide, nano niobium carbide, trimethylolpropane trimercaptopropionate, an antioxidant and a flatting agent according to a specific ratio. The preparation method comprises the following steps: carrying out melt blending granulation on the three polymer matrixes to obtain a modified resin base material, carrying out dry mixing on the modified resin base material and other components, and carrying out melt extrusion and tape casting. The two key modified compounds are respectively prepared by reacting polytetrahydrofuran with dicyclohexylmethane diisocyanate and then sequentially adding pyridine dimethyl carbinol, lipoic acid lactone and isophorone diamine; and amino polysiloxane reacts with dihydroxyphthalaldehyde, and then amino cresol is added for cyclization to obtain the amino polysiloxane. The coating material disclosed by the invention has excellent wear resistance, low temperature resistance and self-repairing function, and is suitable for extreme environments such as high-pressure hydrogen conveying pipelines.

The invention provides dry-process white paste as well as a preparation method and application thereof, and belongs to the technical field of leather color paste. The white paste is prepared from the following raw materials: acidic aliphatic polyurethane resin, rutile titanium dioxide, a phosphate dispersing agent and an organic solvent, the preparation method comprises the following steps: mixing aliphatic isocyanate, hydroxyl acrylic polyol, an alcohol chain extender, an organic bismuth catalyst and a first solvent, carrying out a polymerization reaction, mixing the obtained polymerization product, a second solvent and isophorone diamine, tackifying, adding a terminator to terminate the reaction, mixing the obtained product with a stabilizer, and carrying out extrusion molding to obtain the polyurethane adhesive. The acidic aliphatic polyurethane resin is obtained. The prepared acidic aliphatic polyurethane resin provides an acidic condition for white paste, the problem of poor phenolic yellow resistance caused by alkalinity of the white paste can be avoided, and the white paste provided by the invention is high in yellowing resistance grade (grade 5, UV-B30W, 4h), and the phenolic yellow resistance can reach grade 4.5 or above.

The invention discloses an alkaline phosphatase response type near-infrared fluorescent probe and a preparation method and application thereof, the fluorescent probe is a compound XDM-P, the molecular structure of the fluorescent probe comprises a donor-pi-conjugate-receptor type near-infrared fluorophore constructed by taking xanthene and cyanoisophorone as parent nucleuses, and a recognition group linked by a phosphate bond; the preparation method comprises Knoevenagel condensation, phosphorylation and selective dealkylation reaction. The probe is subjected to specific hydrolysis under the action of alkaline phosphatase (ALP), the intramolecular charge transfer effect is recovered, and near-infrared fluorescence 'OFF-ON' response at 774 nm is realized. The probe provided by the invention has high sensitivity, good linear response and deep tissue penetrating ability, and can be used for intracellular ALP detection and non-invasive, real-time and semi-quantitative in-vivo fluorescence imaging of liver cancer tumor-bearing mouse and drug-induced liver injury mouse models.

The application provides a fluorescent probe of isophorone derivative, a preparation method and application thereof, the fluorescent probe is composed of a naphthalene or coumarin part and an isophorone part, the compound can be used as a fluorescent probe, and can distinguish a lipid droplet and an endoplasmic reticulum in a cell in a double emission channel and a double color. The fluorescent probe composed of the isophorone derivative of the application can distinguish organelles between two emission channels without interference, the fluorophore can produce a large emission shift when the polarity changes, and can emit bright fluorescence under high polarity and low polarity conditions, and provides an important molecular tool for promoting the research on the interaction of organelles.

This invention relates to a low-temperature, fast-drying modified phenolic amine curing agent, its preparation method, and its application. The raw material components of this low-temperature, fast-drying modified phenolic amine curing agent consist of a phenol source, an amine source, an aldehyde source, a modifier, and a solvent. The phenol source includes cashew phenol and phenol; the amine source is selected from one or more of triethylenetetramine, diethylenetriamine, and isophorone diamine; the aldehyde source is formaldehyde solution; the modifier is a silane coupling agent; and the solvent is selected from one or more of xylene, n-butanol, and propylene glycol methyl ether. This low-temperature, fast-drying modified phenolic amine curing agent, its preparation method, and its application have the advantages of low-temperature, fast drying, promotion of nano-ceramic dispersion, and a wide applicable temperature range.

The invention relates to a low-allergy hand lay-up epoxy resin composition as well as a preparation method and application thereof. The low-allergy hand lay-up epoxy resin composition comprises a resin component and a curing agent component, and the low-allergy hand lay-up epoxy resin composition does not contain a diluent; the resin component comprises bisphenol A type epoxy resin and bisphenol F type epoxy resin; the curing agent component is prepared from the following raw materials: isophorone diamine, polyether amine and epoxy resin. The low-allergy hand lay-up epoxy resin composition provided by the invention has the advantages of low allergy and high temperature resistance while ensuring good mechanical properties, can effectively solve the allergy phenomenon of the existing epoxy resin composition in a hand lay-up molding process technology, and is high in practicability.

The application provides a halogen-free flame-retardant laminated resin prepared from component A and component B, wherein the component A comprises modified high phosphorus-containing epoxy resin, dimethyl methylphosphonate, non-crystalline epoxy resin, silane defoaming agent, fluorosilicon defoaming agent and silane coupling agent, and the component B comprises polyether amine, isophorone amine and triethanolamine. The application also provides a preparation method of the halogen-free flame-retardant laminated resin. The halogen-free flame-retardant laminated resin provided by the application has the advantages of low viscosity, good fiber wetting, high hardness, normal-temperature curing, high transparency and good flame-retardant effect due to the selection of specific contents of components and the interaction between the components.

The invention belongs to the field of fluorescent probes for analytical chemistry, and relates to silver ion detection, in particular to an isophorone-based organic fluorescent probe and application thereof in Ag < + > detection. When the isophorone-based organic fluorescent probe is used for detecting silver ions, the fluorescence spectrum of the isophorone-based organic fluorescent probe is remarkably changed before and after detection. By virtue of unique chemical structural characteristics, high-sensitivity quantitative detection of silver ions can be realized, the detection sensitivity is excellent, the lowest detection limit can be as low as 19.63 nM, and the silver ion probe has remarkable application potential in the fields of environmental monitoring and biosensing.

The application discloses an alcohol dehydrogenase mutant with high tea ketone production and application of the mutant in one-pot method, and the mutant is A182L or A182L / V214T. The alcohol dehydrogenase mutant has high catalytic activity on 4-hydroxyisophorone, the yield of tea ketone catalyzed by the mutant A182L / V214T can reach 97%, which is 3.73 times of the original enzyme; the alcohol dehydrogenase mutant has high catalytic activity on synthesis of tea ketone from isophorone in one-pot, the mutant A182L / V214T and cytochrome P450 BM3 The single oxygenase mutant is used in combination to directly obtain tea ketone from isophorone, and the yield of tea ketone can reach 92%; the alcohol dehydrogenase mutant has simple production process, mild reaction condition, and environment-friendly production process in the synthesis of tea ketone, and is favorable for industrialized production of tea ketone, and has wide application prospect.

The application provides a battery diaphragm, a preparation method thereof and a battery. The battery diaphragm is prepared by the following steps: preparing a spinning solution by mixing modified bamboo fiber powder and PET chips, electrospinning to obtain a PET fiber film, finishing the PET fiber film with hexanediamine solution and sulfonated finishing liquid in sequence, and washing, drying to obtain the battery diaphragm. The modified bamboo fiber powder is prepared by the following steps: oxidizing bamboo fiber powder with sodium periodate, and then reacting with an aminated DOPO flame retardant. The aminated DOPO flame retardant is prepared by the following steps: reacting 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide with diethyl maleate, and then reacting with isophorone diamine. The battery diaphragm provided by the application has excellent flame retardant performance and high ion conductivity.

The application discloses a kind of generation (4R) 4-hydroxyisophorone monooxygenase mutant and its preparation method, the monooxygenase is derived from cytochrome P450 of bacillus megaterium BM3 Monooxygenase. The cytochrome P450 BM3 Monooxygenase mutant has high stereoselectivity and high reactivity to catalyze isophorone hydroxylation, mutant A74G / V78A / F87V / L188Q / T327A / A328F catalyzes isophorone to obtain (4R) The diastereomeric excess of 4-hydroxyisophorone can reach 99%, and the yield can reach 98%; the cytochrome P450 BM3 Monooxygenase mutant catalyzes isophorone synthesis (4R) 4-hydroxyisophorone production process is simple, reaction condition is mild, production process is environmental protection, is conducive to industrial production, and has wide application prospect.

The application provides a one-step method for synthesizing theamylone. The method uses alpha-isophorone as a raw material, glycol as a reaction aid, and t-butyl hydroperoxide solution as an oxidant under the condition of concentrated sulfuric acid to prepare the amylone. Compared with the traditional preparation method of the amylone, the method has the advantages of high conversion rate and high selectivity, and can ensure a high yield of the reaction.

The application discloses a preparation method of a ternary catalyst, a catalyst prepared by the method and application of the catalyst. The method comprises the following steps: (1) mixing a magnesium source, a zinc source, urea, citric acid and a solvent, stirring, forming a sol, drying and cooling to form a dry gel, calcining I, and obtaining a precursor; and (2) mixing the precursor and Al2O3 by a mechanical mixing method or a wet kneading method, and calcining II to obtain the ternary catalyst. The catalyst provided by the application can be applied to an isophorone reaction in an acetone condensation process, and has excellent catalytic activity and stability. The preparation method is stable, controllable and good in reproducibility.

The invention discloses an endoplasmic reticulum targeting fluorescent probe as well as a preparation method and application thereof in viscosity detection and viscosity imaging. The preparation method comprises the following steps: mixing and stirring isophorone, malononitrile, piperidine and glacial acetic acid in absolute ethanol, heating to a reflux state, and reacting to obtain an isophorone derivative; the isophorone derivative and 4-hydroxybenzaldehyde are subjected to a condensation reaction to prepare the endoplasmic reticulum targeting fluorescent probe. The fluorescent probe has specific fluorescent response to cell viscosity change, when the viscosity is respectively in the range of 0.89-17.96 cP and 17.96-945 cP, the fluorescence intensity of the probe and the viscosity of a solution present a good linear relationship, and the fluorescent probe has endoplasmic reticulum targeting ability, can be used for detecting inflammation and viscosity imaging in an ER stress process, and also can be used for detecting viscosity imaging in an ER stress process. And the visual imaging of the viscosity of the endoplasmic reticulum in a ferroptosis-mediated acute alcohol stomach injury model can be realized.

This invention discloses an "off-on" type near-infrared fluorescent probe YSQ for lead ion detection, its preparation method, and its applications. This near-infrared fluorescent probe YSQ exhibits strong selectivity for lead ions, a fast response time, significant fluorescence enhancement after complexation, and a low detection limit. Its structure is shown in Formula I below. This invention uses dicyanoisophorone and isoquinoline hydrazide as fluorescent groups to prepare the Schiff base-type fluorescent probe YSQ through a simple condensation reaction. The preparation method of this "off-on" type near-infrared fluorescent probe is simple, the raw materials are readily available, and the obtained product is a solid powder that is easy to store.