Pantoprazole sodium enteric tablet and preparation method thereof
A technology for pantoprazole sodium tablet and pantoprazole sodium, which is applied in directions such as pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, can solve problems such as sticking and flushing, and overcome the Sticky, stable quality, one-sided bright and neat effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0019] Tablets:
[0020] Pantoprazole Sodium 42.3mg
[0021] Mannitol 106.0mg
[0022] Sodium carbonate 10.0mg
[0023] Povidone (PVP K30) 2.0mg
[0024] Crospovidone 10.6mg
[0025] Magnesium stearate 0.7mg
[0026] Silica 3.3mg
[0028] Prepare a suitable adhesive with povidone and a part of sodium carbonate, mannitol and water. The remaining mannitol, sodium carbonate, pantoprazole sodium, and a part of crospovidone are mixed evenly. Then add binder, stir and mix to make soft material, pass through 16 mesh sieve and granulate. After the soft granules are dried, they are sieved through a 16-mesh sieve. Mix the remaining crospovidone, magnesium stearate, silicon dioxide, and talc with the dry granules, and press into tablets. A plain sheet with a certain hardness and bright surface is obtained.
[0029] Isolation layer:
[0030] (1) Alkaline isolation layer
[0031] Hypromellose 4.3mg
[0032] Talc 1.6mg
[0033] Macrogol 6000 1.1mg ...
Embodiment 2
[0048] Tablets:
[0049] Pantoprazole Sodium 42.3mg
[0050] Mannitol 106.0mg
[0051] Sodium carbonate 10.0mg
[0052]Povidone (PVP K30) 2.0mg
[0053] Crospovidone 10.6mg
[0054] Magnesium stearate 0.7mg
[0055] Silicon dioxide 0.85mg
[0057] Prepare a suitable adhesive with povidone and a part of sodium carbonate, mannitol and water. The remaining mannitol, sodium carbonate, pantoprazole sodium, and a part of crospovidone are mixed evenly. Then add binder, stir and mix to make soft material, pass through 16 mesh sieve and granulate. After the soft granules are dried, they are sieved through a 16-mesh sieve. Mix the remaining crospovidone, magnesium stearate, silicon dioxide, and talc with the dry granules, and press into tablets. A plain sheet with a certain hardness and bright surface is obtained.
[0058] Isolation layer:
[0059] Hypromellose 6.3mg
[0060] Talc 2.4mg
[0061] Macrogol 6000 1.6mg
[0062] Titanium dioxide 0.1...
Embodiment 3
[0071] Tablets:
[0072] Pantoprazole Sodium 42.3mg
[0073] Mannitol 106.0mg
[0074] Sodium carbonate 10.0mg
[0075] Povidone (PVP K30) 2.0mg
[0076] Crospovidone 10.6mg
[0077] Magnesium stearate 0.7mg
[0078] Silica 8.5mg
[0079] Talc 8.5mg
[0080] Prepare a suitable adhesive with povidone and a part of sodium carbonate, mannitol and water. The remaining mannitol, sodium carbonate, pantoprazole sodium, and a part of crospovidone are mixed evenly. Then add binder, stir and mix to make soft material, pass through 16 mesh sieve and granulate. After the soft granules are dried, they are sieved through a 16-mesh sieve. Mix the remaining crospovidone, magnesium stearate, silicon dioxide, and talc with the dry granules, and press into tablets. A plain sheet with a certain hardness and bright surface is obtained.
[0081] Isolation layer:
[0082] Hypromellose 6.6mg
[0083] Talc 2.4mg
[0084] Macrogol 6000 1.5mg
[0085] Titanium dioxide 0.12mg
[0086] Dis...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com