The invention relates to a Chinese medicine composition for treating neurasthenia and preparation process of the Chinese medicine composition. The Chinese medicine composition is prepared by the following raw materials: astragalus mongholicus, fructus lycii, poria cocos, cocklebur fruit, herba epimedii, polygala tenuifolia, angelica sinensis, Chinese date, schisandra chinensis, bighead atractylodes rhizome, spina date seed, radix ophiopogonis, Chinese yam, elecampane, cortex albiziae, liquorice, prepared rehmannia root, ginseng, cortex moutan and pinellia ternate. The raw materials are prepared into forms of drugs including capsules, tablets, particles and the like after pharmaceutic adjuvant drugs including starch edible cellulose are added into the raw materials according to a normal preparation method. The Chinese medicine composition for treating the neurasthenia can treat both principal and secondary aspects of the neurasthenia, is free of toxic, harmful and side effect, low in cost and simple and convenient to manufacture, and has wide application prospect.