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Mulberry leaf chewing tablet with sugar-lowering function

A technology of chewable tablets and mulberry leaves, which is applied in the field of mulberry leaf chewable tablets containing xylitol, can solve the problems of poor taste and easy bitter taste, and achieve the effects of avoiding side effects, rich sources, and controlling diabetic complications

Inactive Publication Date: 2009-06-03
TIANJIN JINGUIGU XYLITOL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A company in Japan made mulberry leaves into teabags for sale, and conducted feedback surveys on drinkers. The results showed that the product could improve the symptoms of diabetes and enhance physical fitness, but it tends to have a bitter taste when drinking, and the taste is not very good
In particular, mulberry leaf chewable tablets made of a single component of mulberry leaves mixed with xylose have not been reported in the literature

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Take 50 grams of dried clean mulberry leaves, decoct in 600ml of water for 3 hours, decoct in 500ml of water for 2 hours, decoct in 500ml of water for 2 hours, concentrate to a specific gravity of 1.2, and centrifuge at high speed; the supernatant is passed through a macroporous resin such as AB- Type 8 resin, eluted with water until there is no polysaccharide component, concentrated eluent, precipitated with 85% alcohol, filtered, vacuum dried, crushed and sieved or spray dried to obtain 11 grams of yellow fine powder extract for future use.

Embodiment 2

[0025] 11 grams of fine powdered mulberry leaf extract, 10 grams of xylitol, 100 grams of sorbitol, 40 grams of citric acid, 5 grams of aspartame, 350 grams of starch, 80 grams of dextrin, 10 grams of magnesium stearate, prepared into 220 tablets.

Embodiment 3

[0027] 10 grams of finely powdered mulberry leaf extract, 18 grams of xylitol, 18 grams of sorbitol, 0.9 grams of citric acid, 0.5 grams of aspartame, 57.6 grams of starch, 14.4 grams of dextrin, and 1.5 grams of magnesium stearate. into 100 tablets.

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Abstract

The invention discloses a mulberry leaf chewing tablet with sugar-lowering function. The chewing tablet is characterized by being made from the following raw materials by weight: 1-10 parts of a fine powder extract, 10-80 parts of a pharmaceutic adjuvant and 1-30 parts of xylitol, wherein, the fine powder extract is the mulberry leaf fine powder extract containing not less than 20% of total flavonoid and is obtained by the following steps: decocting dried and cleaned mulberry leaves in water; condensing and centrifuging the obtained decoction at a high speed; adsorbing the obtained centrifugate with resin; eluting with 85% ethanol and performing alcohol precipitation; drying in vacuum after precipitation and dehydration; smashing, sieving and drying. The mulberry leaf chewing tablet can effectively control blood sugar level increase without being metallization by insulin, and provides a good clinical drug for diabetics.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a xylitol-containing mulberry leaf chewable tablet with hypoglycemic effect. Background technique [0002] Xylitol is a therapeutic agent, a nutritional agent and the best sweetener for diabetics. Diabetes is listed as the third largest "killer" after AIDS and cancer in the medical field, and is known as "sub-cancer". According to the survey of more than 40,000 permanent residents aged 20-74 in 11 provinces (municipalities) by the Chinese Academy of Preventive Medicine, the results show that the incidence of the disease is 3.12%, and those with impaired glucose tolerance are 4.76%. The total number of people with impaired glucose tolerance can reach 50-60 million. Less than 5% of them belong to type I, which is more common in children and adolescents, with acute onset and severe insulin deficiency in the body. More than 95% of them belong to t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23G3/48A23G3/38A23L1/29A23L1/09A23P1/02A61K36/605A61K9/20A61P3/10
Inventor 马永华邱洪江
Owner TIANJIN JINGUIGU XYLITOL
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