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1306 results about "Flavones" patented technology

Flavones (flavus = yellow), are a class of flavonoids based on the backbone of 2-phenylchromen-4-one (2-phenyl-1-benzopyran-4-one) (right image). Flavones are common in the food supply, mainly from spices, and red–purple fruits and vegetables. Common flavones include apigenin (4',5,7-trihydroxyflavone), luteolin (3',4',5,7-tetrahydroxyflavone), tangeritin (4',5,6,7,8-pentamethoxyflavone), chrysin (5,7-dihydroxyflavone), and 6-hydroxyflavone.

Piggy creep feed containing composite flavone and preparation method thereof

InactiveCN105614104Aresist invasionImprove bowel functionAccessory food factorsAnimal scienceFlavones
The invention discloses piggy creep feed containing composite flavone. The piggy creep feed is prepared from the following raw materials in parts by weight: 13 to 20 parts of expanded corn, 10 to 25 parts of corn, 6 to 13 parts of broken rice, 8 to 12 parts of flour, 8 to 15 parts of whey mist, 3 to 8 parts of soy protein concentrate, 5 to 10 parts of extruded soybean, 0.7 to 3 parts of soya-bean oil, 7 to 12 parts of 46.5-percent bean pulp, 2 to 5 parts of fish meal, 2 to 5 parts of plasma protein powder, 0.3 to 0.7 part of mountain flour, 0.5 to 1.0 part of calcium hydrophosphate, 0.05 to 0.5 part of lysine, 0.05 to 0.3 part of threonine, 0.1 to 0.3 part of sodium chloride, 0.1 to 0.8 part of compound flavone premix compounds, 0.15 to 0.3 part of zinc oxide, 0.03 to 0.06 part of calcium propionate, 0.02 to 0.04 part of ethoxyquin and 1.0 part of suckling pig premix compounds. The invention also discloses a preparation method. The intestinal tract health and the production performance of weaned pigs can be improved.
Owner:ZHANGZHOU AONONG ANIMAL HUSBANDRY TECH

Calendula double-bacterium fermentation product as well as preparation method and application thereof

The invention discloses a calendula double-bacterium fermentation product as well as a preparation method and application thereof, and relates to the technical field of plant fermentation. The preparation method of the calendula double-bacterium fermentation product disclosed by the invention comprises the following steps: carrying out primary fermentation by using lactobacillus plantarum, then carrying out secondary fermentation by using saccharomyces cerevisiae, and carrying out sterilization and filtration treatment on the calendula fermentation liquid subjected to secondary fermentation, so as to obtain the calendula fermentation liquid. The calendula fermentation liquor is subjected to combined fermentation through lactobacillus plantarum and saccharomyces cerevisiae, and the content of polyphenol and flavone in the calendula double-bacterium fermentation product is remarkably increased. Meanwhile, the calendula double-bacterium fermentation product has the effects of preserving moisture, resisting oxidation, relieving and controlling oil, and has a wide application prospect in the field of cosmetics.
Owner:济南泽润生物科技有限公司

Plant-source nutritional supplement based on glycoside compounds and preparation method of plant-source nutritional supplement

The invention discloses a plant-source nutritional supplement based on glycoside compounds and a preparation method thereof, and relates to the technical field of preparation of plant-source nutritional supplements.The preparation method comprises the steps that raw materials are prepared; the preparation method comprises the following steps: respectively carrying out ultrasonic-assisted extraction on flavonoid glycoside, saponin and geniposide raw materials to obtain an extracting solution; carrying out centrifugal separation on the extracting solution, taking supernate, and then purifying by adopting a macroporous resin adsorption method to obtain a purified glycoside compound solution; mixing the purified glycoside compound solution with lycium barbarum polysaccharide, Chinese yam starch, vitamin E and other auxiliaries in proportion, and uniformly stirring to form a mixed solution; carrying out spray drying on the mixed solution to obtain a powdery nutritional supplement; and screening the powdery nutritional supplement. The high-purity plant source glycoside compound and the functional auxiliary agent are scientifically compounded, and ultrasonic extraction, resin purification and precise process control are combined, so that the integrated improvement of activity synergy, quality stability and personalized scene adaptation of the nutritional supplement is realized.
Owner:HUBEI BOHAI BIO-HOLDING GROUP CO LTD

Psoralea corylifolia total flavone extract and preparation method and application thereof in promoting hair growth

PendingCN120732918AAerosol deliveryOintment deliveryBiotechnologyAlopecia treatment
The invention discloses a fructus psoraleae total flavone extract as well as a preparation method and application thereof in promoting hair growth. According to the preparation method of the fructus psoraleae total flavone extract, the specific eutectic solvent is adopted, the ultrasonic technology is combined for extraction, the content of total flavone in the fructus psoraleae extract can be remarkably increased, and the fructus psoraleae total flavone can be efficiently extracted; and the adopted extraction solvent has the advantages of greenness, environmental protection, efficient process, low cost, high safety and the like, and can solve the problems of the existing extraction process. The malaytea scurfpea fruit total flavone extract obtained by the method has the effect of promoting hair growth and can remarkably promote hair follicle cell proliferation and prolong the hair growth period, the prepared external gel product has the hair growth effect, the preparation method is simple, and external use is convenient. The malaytea scurfpea fruit total flavone extract provided by the invention can be used for developing more cosmetics and medical products for preventing alopecia and promoting hair growth, and a new scheme is provided for green extraction of natural active ingredients and treatment of alopecia.
Owner:GUANGDONG UNIV OF TECH

Method for extracting and purifying flavone in litsea coreana through ultrasonic-assisted eutectic solvent

The invention discloses a method for extracting and purifying flavone in litsea coreana through an ultrasonic-assisted eutectic solvent, and belongs to the technical field of green processing of natural products. The invention provides a method for efficiently preparing litsea coreana flavone by integrating computer prediction, green solvent extraction and resin purification technologies. The method comprises the following steps: firstly, calculating and screening a deep eutectic solvent system with the highest affinity with the litsea coreana flavone on the basis of a COSMO-RS theoretical model, then coupling the optimized DES with an ultrasonic-assisted extraction (UAE) technology, and through the synergistic effect of the DES and the UAE technology, remarkably improving the extraction rate of the litsea coreana flavone and furthest keeping the biological activity of a target component; then, a macroporous resin dynamic adsorption-desorption purification process is linked, so that high-selectivity enrichment and impurity removal of the flavonoid compounds in the crude extract are realized, a high-purity product is obtained, and a complete process route from intelligent screening, efficient extraction to precise purification is finally formed.
Owner:CHONGQING ACAD OF AGRI SCI +1

Aspergillus niger strain, culture method and application thereof

The application discloses an Aspergillus niger strain and a culture method and application thereof, the Aspergillus niger strain is preserved in China Center for Type Culture Collection, and the preservation number is CCTCC NO: M 20241727. The fermented tea product obtained by fermenting tea leaves or tea leaf extracts by using the Aspergillus niger strain CCTCC NO: M 20241727 has prominent sweet and floral fragrance, and the astringency is obviously reduced; the contents of tea polyphenols, free amino acids and flavones are higher than those of a fermented tea product of an existing Aspergillus niger strain; the antioxidant activity is enhanced; the tea soup color is orange red and bright; and the color, fragrance and taste qualities are all superior to those of the fermented tea product of the existing Aspergillus niger strain.
Owner:ANHUI AGRICULTURAL UNIVERSITY

Tartary buckwheat herbal white spirit and preparation method thereof

The invention provides tartary buckwheat herbal baijiu and a preparation method thereof.The method aims at solving the problems that existing tartary buckwheat baijiu is lost in active ingredient, single in flavor and unstable in baijiu body, firstly, tartary buckwheat submicron powder, radix puerariae submicron powder and rhizoma polygonati submicron powder are put into Maotai-flavor base liquor together, and two-section type closed extraction is conducted at the normal temperature and then at the low temperature, adding a part of citric acid solution to adjust the pH at the initial stage of extraction; squeezing and filtering extract liquor, immediately adding bamboo leaf extract and phytic acid to carry out synergistic anti-oxidation treatment, and carrying out short-term aging; and finally, blending with the residual base wine. According to the preparation method disclosed by the invention, the retention rate of active ingredients such as tartary buckwheat flavone and the stability of the wine body are remarkably improved through staged extraction and dual antioxidant protection, the wine body is successfully endowed with coordinated baking fragrance, sauce fragrance and herbal flavor, and the taste is mellow and mild.
Owner:GUIZHOU INST OF BIOTECHNOLOGY (GUIZHOU KEY LAB OF BIOTECHNOLOGY GUIZHOU POTATO RES INST GUIZHOU FOOD PROCESSING RES INST)

Extraction method of eucommia ulmoides with intestinal repair function

The invention discloses a method for extracting eucommia ulmoides with an intestinal repair function, and relates to the technical field of natural product extraction.The method comprises the steps that a fresh eucommia ulmoides raw material is subjected to low-temperature drying and smashing, a polysaccharide water extract and filter residues are obtained through water extraction, and then the flavone residual quantity in the polysaccharide water extract is synchronously detected; carrying out enzymolysis on the polysaccharide water extract through beta-glucanase to obtain a small molecular polysaccharide solution, and carrying out alcohol extraction on filter residues to obtain a flavone alcohol extract; the preparation method comprises the following steps: mixing the two components according to a ratio, inoculating compound probiotics for anaerobic fermentation, regulating according to the residual quantity of flavone, regulating an alcohol extraction process by using short-chain fatty acid generated by fermentation when the residual quantity is high, supplementing flavone extract in an enzymolysis system when the residual quantity is low, and finally removing impurities, purifying, adapting intestinal tracts and drying to obtain the product. According to the method, regulation and control operation is correspondingly executed by detecting the residual quantity of flavone in the polysaccharide water extract, so that self-supply of a regulation and control reagent and high efficiency of active ingredients are realized, the conversion rate of small molecular polysaccharide and flavone aglycone is increased, and the intestinal tract tolerance of the product is optimized.
Owner:湖南省兽药饲料监察所(湖南省畜禽水产品质量检验检测中心)

Phytobacterium plantarum NXU-F1 and application thereof

The invention belongs to the technical field of microorganisms, and relates to a plant lactobacillus NXU-F1 strain and application thereof. The classification name of the bacterial strain is lactobacillus plantarum, the bacterial strain is preserved in Guangdong Microbial Culture Collection Center on June 20, 2025, and the preservation number of the bacterial strain is GDMCC No.66563. The invention also discloses a preparation method of the bacterial strain. The plant lactobacillus is strong in growth capability, has good adaptive capacity to environment, and can obviously increase the content of antioxidant substances when being applied to plant matrix fermentation. The lycium barbarum and grape compound fermented beverage is prepared by fermenting the lycium barbarum and grape compound fermented beverage, the content of polyphenol, flavone, polysaccharide and procyanidine in the beverage is obviously increased, and the increase of resveratrol and ferulic acid is particularly obvious; meanwhile, ester compounds are increased and aldehyde substances are reduced, so that the beverage is endowed with strong longan fruity flavor, and the flavor of harmonious sour and sweet taste and lingering aftertaste is formed.
Owner:NINGXIA UNIVERSITY

Ginkgo biflavone-containing skin anti-wrinkle whitening composition and preparation method thereof

The invention discloses a skin anti-wrinkle whitening composition containing ginkgetin and a preparation method of the skin anti-wrinkle whitening composition. The composition takes ginkgo biflavone as a main active component, has the characteristics of safety and effectiveness, can remarkably improve skin elasticity and reduce wrinkles, and has the effect of whitening skin.
Owner:SHANGHAI DERMATOLOGY HOSPITAL

Targeted prebiotic plant extraction dietary powder for relieving hypeluricemia and preparation technology of targeted prebiotic plant extraction dietary powder

The invention discloses targeted prebiotic plant extraction dietary powder for relieving hyperuricemia and a preparation technology of the targeted prebiotic plant extraction dietary powder, and belongs to the technical field of dietary powder.In a formula of the targeted prebiotic plant extraction dietary powder for relieving hyperuricemia, as a patented bacterial strain, the bacillus coagulans MKSWC01 can directly act on the intestinal tract environment, uric acid precursor substances generated by purine metabolism are degraded in a targeted mode, and generation of uric acid is reduced from the source; the chicory root superfine powder and the mulberry leaf DNJ extract respectively activate kidney excretion protein, inhibit the activity of glycosidase, accelerate discharge of uric acid through urine and block the path of conversion from fructose metabolism to uric acid; the celery seed flavone and the smilax glabra polysaccharide further play an anti-inflammatory role, the deposition risk of urate crystals at joints is reduced, and potential inflammatory response caused by hyperuricemia is relieved. Meanwhile, the resistant dextrin and the xylooligosaccharide serve as prebiotics, nutrients are provided for probiotics to support planting of the probiotics, the overall metabolic environment can be improved by adjusting intestinal flora balance, the pathological link of hyperuricemia is comprehensively covered, and the relieving effect is improved.
Owner:CHANGSHA KANGJIN FUCUI TECHNOLOGY CO LTD

Leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite

The invention relates to the technical field of aquaculture, in particular to a leiocassis longirostris intestinal health functional additive based on spermaceti soxhlet metabolite. The Leiocassis longirostris intestinal health functional additive comprises the following functional components: chondroitin sulfate, N-acetyl-D-galactosamine, 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4', 4 ', 4'- The composition is prepared from the following raw materials: 4, 6-dihydroxyflavone, polydatin, ascorbic acid, glucoside, arabinogalactan, 3-O-beta-D-galactopyranosyl-L-arabinose, tyramine, 4A-hydroxytetrahydrobiopterin, hyaluronic acid and 3-mercapto-2-butanol. According to the technical scheme, the technical problem that an existing probiotic viable bacterium preparation is difficult to meet the intestinal health management requirement in intensive culture of the leiocassis longirostris can be solved. Compared with the prior art, the scheme is more efficient, stable and safe, healthy development of the Leiocassis longirostris breeding industry can be effectively promoted, and the method has ideal application and popularization prospects.
Owner:FISHERIES INST SICHUAN ACADEMY OF AGRI SCI

Immune-enhanced fermented functional feed for prawns and preparation method thereof

PendingCN120732098AAnimal feeding stuffAccessory food factorsCitrus aurantium extractProbiotic bacterium
The invention provides a prawn immunity-enhanced fermented functional feed and a preparation method thereof. Belongs to the field of animal feed. The feed comprises a basal feed and a feed additive, the feed additive comprises the following components: lactobacillus plantarum fermentation liquor, passion flower flavone and an immature bitter orange extract. Three functional components including the lactobacillus plantarum fermentation liquor, the passion flower flavone and the immature bitter orange extract are fused, a synergistic interaction system is constructed through a definite proportion, and the immunity of prawns is remarkably improved; the sources and the content of effective components of the immature bitter orange extract and the lactobacillus plantarum fermentation liquor are strictly limited, and the controllable product quality is ensured; the preparation process of the feed is simple, the key growth stage of shrimp culture is accurately positioned, and a comprehensive solution integrating probiotic regulation and control, plant active ingredient immune activation and process feasibility is provided for healthy culture of prawns.
Owner:GUANGZHOU LYUBAIDUO BIOLOGICAL DEV CO LTD

Ultrasonic-assisted method for impregnating coffee beans with fructose

PendingCN121080545APre-extraction tea treatmentTea flavoringBiotechnologyRobusta coffee bean
The invention discloses a method for impregnating coffee beans with fructose under the assistance of ultrasonic waves, and relates to the technical field of food processing, and the method is technically characterized by comprising the following steps: selecting Robursta coffee beans with the moisture content of 10-12%; mixing with a 5% fructose solution according to a solid-liquid ratio of 1: 4, treating for 5-20 minutes (preferably 5 minutes) under ultrasonic waves of 40 kHz and 120 W, and totally impregnating for 4 hours; performing forced air drying at 40 DEG C for 23h until the water content is 10- And baking at the temperature of 175 DEG C for 7-8 minutes. A honeycomb net structure is formed on the surface of the coffee beans through ultrasonic treatment, the total sugar content is remarkably increased to 54.65 mg / g, amino acid composition is affected, and bioactive substances such as polyphenol and flavone are increased. The score of the baked coffee beans is more than 72 (the score of the coffee beans is 74.92 after the coffee beans are subjected to ultrasonic treatment for 5 minutes) through an SCA cup test, and the coffee beans have caramel fragrance, nut fragrance and smoother mouth feel. The method is simple and convenient to operate, low in cost and capable of effectively improving the flavor quality of the Robursta coffee.
Owner:SPICE & BEVERAGE RES INST CHINESE ACAD OF TROPICAL AGRI SCI +1

Key gene for biosynthesis of large-fruit hawthorn flavonoid compound as well as screening method and application of key gene

ActiveCN121915057AMicrobiological testing/measurementPlant peptidesSecondary metabolite biosynthesisPlant secondary metabolism
The invention belongs to the technical field of biosynthesis of plant secondary metabolites, and particularly relates to a key gene for biosynthesis of large-fruit hawthorn flavonoid compounds and a screening method and application of the key gene. Through combined analysis of metabolome and transcriptome, a key gene combination containing seven structural genes and three transcription factor genes is screened out; the expression of the genes is remarkably positively correlated with the accumulation of a target flavone metabolite [6]-gingerol, and the genes are core factors for regulating and controlling the synthesis of the flavonoid compounds of the big-fruit hawthorns through experimental verification. According to the invention, the key gene for regulating and controlling the synthesis of flavone substances such as [6]-gingerol in the big hawthorn fruit is systematically identified for the first time, and a target spot is provided for analyzing a quality formation mechanism from a molecular level; the gene can be used for molecular marker-assisted breeding so as to cultivate a new variety of large-fruit hawthorn with high flavone content, and also can provide gene resources and technical support for the development of functional food and health care products.
Owner:GUANGXI ZHUANG AUTONOMOUS REGION ACAD OF AGRI SCI +1

Method for extracting rose flavone

The invention discloses an extraction method of rose flavonoids, which comprises the following steps: S1, crushing selected dry Hetian rose buds, and storing for later use; s2, accurately weighing 1g of rose powder and putting the rose powder into a conical flask; s3, then, according to the material-liquid ratio of 1: 40, 40% ethanol is used as a solvent, and the materials are poured into a conical flask to be mixed; and S4, finally, soaking in a constant-temperature water area, extracting for 2 hours, and finally, taking supernate for later use. According to the invention, the solid-liquid ratio of 1: 40 ensures that the rose powder is fully infiltrated by an enough solvent (40% ethanol). Under the proportion, the ethanol can be in full contact with target components (such as flavonoid compounds and the like) in the rose powder. Each 1g of rose powder is surrounded by 40ml of solvent, so that target components have more opportunities to be dissolved out of powder particles to enter the solvent, and the extraction completeness can be improved compared with the condition that a feed liquid is relatively small.
Owner:XINJIANG YUTIAN QUEME BIOTECH CO LTD

Application of LmbZIP11 gene in regulating and controlling content of chlorogenic acid and total flavonoids

The invention relates to a method and application of an LmbZIP11 gene and a homologous NbbZIP11 gene of the LmbZIP11 gene in regulating and controlling the content of chlorogenic acid and total flavonoids in plants. The method comprises the following steps: extracting RNA (Ribonucleic Acid) of leaves of lonicera macranthoides, designing a specific primer, cloning to obtain an LmbZIP11 gene, further constructing a recombinant overexpression vector and a VIGS (Vinyl Insulin Growth Sequence) silencing vector of the LmbZIP11 gene, and respectively transforming arabidopsis thaliana and nicotiana benthamiana; experiments show that the content of total flavonoids and chlorogenic acid in arabidopsis thaliana is remarkably increased through overexpression of the LmbZIP11 gene, and the content of metabolites in tobacco is remarkably reduced through silence of the NbbZIP11 gene homologous with the LmbZIP11 in Benen tobacco; the invention provides a new strategy for regulating the synthesis of plant secondary metabolites by using the LmbZIP11 gene, and can be used for improving the quality of medicinal plants.
Owner:HUNAN AGRI UNIV

Hypoglycemic composition containing supramolecular group composite peptide and application of hypoglycemic composition in functional food and medicine

The invention discloses a hypoglycemic composition containing supramolecular group composite peptide. The hypoglycemic composition comprises collagen peptide, soybean peptide, bitter gourd peptide, bamboo leaf flavone, L-carnitine and the like. The composition prepared by selecting raw material components of specific types and dosages has the effects of remarkably reducing the glucose level and increasing the insulin level, and part of the composition can also cooperate with metformin to achieve the effects of enhancing the effect of reducing blood sugar and improving or preventing type 2 diabetes mellitus. Therefore, the method can be used for developing functional foods and medicines and has a considerable market prospect.
Owner:HANGZHOU HUANTE BIOLOGICAL TECH CO LTD

Method for extracting and detecting active substances of hemerocallis fulva and application of active substances

The invention provides an extraction and detection method of a day lily active matter and application of the day lily active matter in anti-neuritis. Hemerocallis fulva contains various bioactive substances including flavone, polysaccharide and saponin, and the substances have potential application value in the fields of medicines and health care products. The invention provides a method for extracting the active components step by step, and rapid identification and detection are carried out by utilizing technologies such as fluorescence and ultraviolet-visible spectrophotometry. In addition, the invention also develops a detection method for evaluating the anti-neuritis effect of the active substances. Lipopolysaccharide (LPS) is used for stimulation to establish an inflammation model, day lily active substances are added, and the active substances are found to be capable of remarkably inhibiting generation and release of inflammatory factors and promoting growth and differentiation of neurons. Scientific basis is provided for developing new neuritis treatment methods, related drugs and the like.
Owner:SHAANXI INST OF BIOLOGICAL AGRI

Hippophae rhamnoides soft capsule and production process thereof

The invention is applied to the technical field of health-care products, and discloses a sea-buckthorn soft capsule, which comprises a capsule shell and a content, the capsule shell is composed of gelatin, water, glycerin and an auxiliary material, the auxiliary material is a preservative or a plasticizer, the content is composed of one of seabuckthorn seed oil or fruit oil, seabuckthorn powder and an auxiliary material, the auxiliary material is one of a suspending aid and an antioxidant or a mixture of the suspending aid and the antioxidant, the seabuckthorn powder is rich in flavone, and the auxiliary material is a mixture of the suspending aid and the antioxidant. The soft capsule has the effects of lowering lipid, softening blood vessels and preventing vascular diseases. According to the hippophae rhamnoides soft capsule, a product capsule shell is prepared from gelatin, water and glycerin according to a specific proportion, it can be guaranteed that the capsule shell has proper hardness and elasticity and is convenient to process and store, hippophae rhamnoides seed (fruit) oil and hippophae rhamnoides powder in the content are matched according to a reasonable proportion, the hippophae rhamnoides powder is rich in flavone, and the hippophae rhamnoides powder and the hippophae rhamnoides seed (fruit) oil act the effects of lowering lipid, softening blood vessels and preventing vascular diseases can be better exerted.
Owner:SHANXI XIAONIUWA FOOD CO LTD

A method for mechanical chemistry-assisted extraction of total flavonoids from hibiscus flowers

This invention discloses a mechanochemical-assisted extraction method for total flavonoids from Hibiscus mutabilis flowers. Hibiscus mutabilis flowers and an auxiliary agent are added to a ball mill jar, zirconium beads are added as the grinding medium, and the jar is placed in a ball mill for co-grinding. After the reaction, the product is separated from the zirconium beads, and the ball-milled product is ultrasonically extracted with water to obtain a crude extract of total flavonoids from Hibiscus mutabilis flowers. This invention utilizes a mechanical ball milling reaction between the auxiliary agent and Hibiscus mutabilis flower powder. Under mechanical force, the particle size of the dried coarse Hibiscus mutabilis flower powder decreases, and the cell structure is destroyed, promoting the release of its active ingredients. Furthermore, by selectively adding solid reagents during co-grinding, utilizing the physicochemical properties of flavonoids, the flavonoids and auxiliary agent form salts under mechanical force, thereby increasing the extraction rate of flavonoids in water. Compared with existing extraction methods, this method has advantages such as environmental friendliness, good water solubility, high extraction rate, and simple operation, and has broad market application prospects.
Owner:ZHEJIANG UNIV OF TECH +1

Method for extracting boxthorn leaf total flavonoids by using ultrasonic-assisted deep-eutectic solvent and application of boxthorn leaf total flavonoids

The invention belongs to the technical field of active substance extraction, and discloses a method for extracting boxthorn leaf total flavonoids through an ultrasonic-assisted deep-eutectic solvent and application of the boxthorn leaf total flavonoids. Heating and mixing the hydrogen bond acceptor and the hydrogen bond donor, stirring to be transparent, and adding water to reduce viscosity to obtain the eutectic solvent; mixing the boxthorn leaf powder with a deep-eutectic solvent, performing ultrasonic extraction and centrifugation, and collecting supernate; adsorbing by using macroporous resin, washing and desorbing to obtain an eluent; and performing vacuum freeze drying to constant weight. According to the method disclosed by the invention, the eutectic solvent with low melting point and strong solubility is selected, the flavonoid compounds in the boxthorn leaves are green and efficiently extracted, and the total flavonoid content of the boxthorn leaves obtained by taking the eutectic solvent as an extraction solvent is 123.94 + / -1.04 mg / g and is far higher than the total flavonoid content of the boxthorn leaves obtained by traditional ethanol extraction by 64.60 + / -0.87 mg / g; the method is good in safety, short in time consumption and high in extraction rate.
Owner:TIANJIN UNIV OF SCI & TECH

Galikalii-euphorbia tripsacus composite extract as well as preparation method and vagina repair application thereof

The invention discloses a galiaceae-euphorbia tripsacus compound extract as well as a preparation method and vagina repair application thereof. The compound extract is prepared from galiaceae herbs and euphorbia tripsacus according to a scientific ratio through compound enzymolysis pretreatment, gradient ethanol solvent step-by-step extraction and double-resin series purification. According to the preparation method, the dissolution rate of the active components is remarkably increased by utilizing an enzymolysis wall breaking technology, the problem that the purity of the multi-polar components (tannin, flavone and polysaccharide) is difficult to increase and extract at the same time is solved through gradient extraction and series purification, and the purity of the total active components is more than or equal to 60%. The obtained composite extract has multiple effects of astringing and tightening, promoting regeneration of elastic fibers and improving contractility of smooth muscles, and is safe and non-irritant. The invention further discloses targeted sustained-release gel containing the extract, and the targeted sustained-release gel can be used for improving vaginal relaxation and deeply repairing private parts.
Owner:SHANGHAI MEIHA BIOTECHNOLOGY DEV CO LTD

Rose enzyme liquid and rose enzyme beverage for promoting emotional health, and preparation method therefor

The present invention relates to the technical field of functional food products. Disclosed are a rose enzyme liquid and rose enzyme beverage for promoting emotional health, and a preparation method therefor. Sour cherry flesh, double-petaled red roses, roselle, and Perillae folium are subjected to a colloid mill, and water is added for extraction and separation to obtain a concentrate. The concentrate is fermented with Lactiplantibacillus plantarum and Bifidobacterium longum to obtain a rose enzyme liquid, and the rose enzyme liquid is compounded with a saffron extract, a Mentha spicata extract, a bamboo leaf flavonoid, etc. to obtain a rose enzyme beverage. The rose, roselle, sour cherry and Perillae folium, which are both medicinal and edible, are selected as raw materials. The raw materials are fermented by means of using specific probiotic strains to effectively release active ingredients, which are then converted into small molecular substances that are easily absorbed by the human body and relieve emotional anxiety. Moreover, functional ingredients comprising the saffron extract, the Mentha spicata extract and the bamboo leaf flavonoid are compounded to effectively relieve stress, regulate daily negative emotions, and promote physical and mental relaxation, and enhance mental well-being. The sour and sweet taste satisfies consumers' pursuit for flavor, taste and efficacy.
Owner:RENHE GLOBAL (SHANGHAI) GRAND HEALTH RESEARCH INSTITUTE CO LTD

Mulberry leaf flavone microcapsule as well as preparation and application thereof

The invention discloses a mulberry leaf flavone microcapsule which is prepared by taking mulberry leaf flavone extracted from mulberry leaves as a core material, taking mulberry leaf residue polysaccharide re-extracted from mulberry leaf residues left after the extraction of the mulberry leaf flavone and gelatin as a wall material and adopting a complex coacervation method. Before the complex coacervation reaction, the wall material solution needs to be subjected to electric field pulse treatment by adjusting the pH value to 3-3.5, and then subjected to electric field pulse treatment by adjusting the pH value to 6-7; after the wall material and the core material are mixed, a mixed solution needs to be cooled firstly, and then glutamine transaminase is added for a complex coacervation reaction. According to the mulberry leaf flavone microcapsule disclosed by the invention, the mulberry leaf residue polysaccharide and the gelatin are used as composite wall materials to carry out microencapsulation embedding on mulberry leaf flavone, and a flavone delivery system with a slow release function is constructed, so that not only is the reutilization of mulberry leaf residue wastes realized, but also the extracted mulberry leaf residue polysaccharide can be in synergistic interaction with the gelatin; therefore, the obtained mulberry leaf flavone microcapsule is excellent in stability, bioavailability and blood fat reducing effect.
Owner:HEBEI UNIV OF SCI & TECH +1

Selenium-enriched ginkgo flavone traditional Chinese medicine health wine and preparation method thereof

The invention belongs to the technical field of preparation of health-preserving drinks, and particularly relates to selenium-enriched ginkgo flavone traditional Chinese medicine health-preserving wine and a preparation method of the selenium-enriched ginkgo flavone traditional Chinese medicine health-preserving wine. Comprising the following raw materials in parts by mass: 10 parts of corn kernels, 3-5 parts of mushrooms, 6 parts of oat, 3 parts of soybeans, 3.5-5.5 parts of ginkgo leaves, 2 parts of Chinese dates, 1.5 parts of crystal sugar, 0.8-1.2 parts of honey, 0.8-1.2 parts of fruit juice modified liquid and 1 part of a traditional Chinese medicine extracting solution. According to the selenium-enriched ginkgo flavone traditional Chinese medicine health-preserving wine, corn kernels, mushrooms, oats and soybeans are used as selenium-enriched raw materials, long-chain polysaccharides of the corn kernels, the mushrooms, the oats and the soybeans form a compound, and flavone protection and selenium absorption promotion are achieved in combination with a colloid environment and fruit juice modified liquid; polysaccharide, organic selenium and ginkgo flavone are cooperated, so that the health-care wine is upgraded to target conditioning; through'chemical reaction-slow release conversion ', bitterness is covered, flavor is increased, and health preserving and taste are balanced.
Owner:BEIJING CIMINGTANG MEDICAL RES INST

Composite plant polypeptide composition with functions of repairing pancreas and reducing blood sugar

The invention discloses a composite plant polypeptide composition with the effects of repairing pancreas and reducing blood sugar. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 50 parts of ginsenoside, 5 to 30 parts of radix astragali seu hedysari extract, 3 to 20 parts of radix rehmanniae polysaccharide, 2 to 15 parts of radix trichosanthis alkaloid, 5 to 25 parts of rhizoma dioscoreae polysaccharide, 5 to 30 parts of bitter gourd polypeptide, 3 to 20 parts of folium mori alkaloid, 8 to 40 parts of rhizoma polygonati polysaccharide, 5 to 25 parts of fructus hippophae flavone, 10 to 35 parts of wheat germ peptide, 2 to 15 parts of coptis berberine, 10 to 45 parts of corn stigma polysaccharide and 3 to 20 parts of saussurea involucrata polyphenol. 1-10 parts of sophora flavescens total alkaloids, 5-25 parts of a dendrobium extract, 5-30 parts of a radix puerariae extract, 8-35 parts of L-arabinose and 10-40 parts of small molecule peptides; 20 to 100 parts of collagen peptide and 15 to 80 parts of albumin peptide; 5-50 parts of microcrystalline cellulose, 3-30 parts of fructo-oligosaccharide and 0.5-5 parts of magnesium stearate; the limitation of single sugar control or simple component mixing in the prior art is broken through, a synergistic system of plant active components and functional polypeptides is constructed, and the purity and retention rate of the plant active components are improved by optimizing the extraction process.
Owner:孟云富

Co-fermentation method based on sphingomonas and rhodiola rosea extracting solution and application of product

The invention discloses a co-fermentation method based on sphingomonas and a rhodiola rosea extracting solution and application of a product, and belongs to the technical field of microorganisms. By utilizing a special rich enzyme system of sphingomonas and combining with an early-stage composite enzymolysis process and synergistic effect, the wall breaking efficiency of rhodiola rosea cell walls and the conversion degree of active components of rhodiola rosea are greatly improved, the bottlenecks of low efficiency and low bioavailability of a traditional rhodiola rosea extraction method are successfully overcome, and the rhodiola rosea extraction method is suitable for industrial production. The functional components such as salidroside and flavone can be fully released and converted. Secondly, different from non-symbiotic bacteria (such as lactic acid bacteria and saccharomycetes) which are commonly used for fermentation in the prior art, a potential symbiotic bacterium of sphingomonas XJL-TP07 from a special environment is innovatively selected and has better metabolic suitability with the rhodiola rosea component, the fermentation process is milder and safer (no irritant is produced), and the rhodiola rosea fermentation method is suitable for large-scale production. And a synergistic interaction effect can be generated through a unique biotransformation path.
Owner:DAOTONG ZOTAI (SHANGHAI) BIOPHARMACEUTICAL CO LTD

Application of total flavonoids of chrysanthemum morifolium and metabolites thereof in preparation of uric acid-lowering or liver and kidney protecting drugs or health products

The application discloses application of total flavones of chrysanthemum morifolium ramat and metabolites thereof in preparation of uric acid-lowering or liver and kidney protecting drugs or health care products. The total flavones of chrysanthemum morifolium ramat contain various flavone compounds. In a hyperuricemia model mouse, the total flavones of chrysanthemum morifolium ramat can significantly reduce blood uric acid level, and has a significant protective effect on liver and kidney, and the effect is achieved by inhibiting the activity and expression of xanthine oxidase and adenosine deaminase in the liver, and regulating the expression of uric acid related transporters in the kidney. Meanwhile, metabolites of the total flavones of chrysanthemum morifolium ramat, luteolin-7-O-glucuronide and apigenin-7-O-glucuronide, can also play a pharmacological role in the mouse body. In vitro experiments and mouse primary hepatocytes further prove that luteolin-7-O-glucuronide and apigenin-7-O-glucuronide have an inhibiting effect on the activity and expression level of xanthine oxidase. The application widens the application range of traditional Chinese medicinal materials, and provides a new direction for development of efficient and low-toxic uric acid-lowering and anti-gout drugs or health care products.
Owner:ZHEJIANG UNIV

Honeysuckle juice low-temperature cold-extraction slow-distillation extraction system and extraction method

The invention discloses a low-temperature cold-extraction slow-distillation extraction system and method for honeysuckle juice, and relates to the technical field of honeysuckle juice extraction. A vacuum slow distillation stage; a low-temperature purification stage; a fermentation stage and a blending stage; according to the method, low-temperature cold extraction is combined with vacuum gradient slow distillation, degradation of heat-sensitive components such as chlorogenic acid and galuteolin is effectively reduced, and the retention rate of the heat-sensitive components is greatly increased; components with different boiling points are collected by stages through gradient distillation, the extraction rate of functional components such as polysaccharide and flavone is increased, and the problem of component loss caused by a traditional high-temperature process is solved. Low-temperature treatment retains more natural aroma substances, gradient distillation makes the aroma level of the product richer, and the flavor is better than that of the original process; the filtration and alcohol precipitation treatment in the low-temperature purification stage significantly improves the clarity qualification rate of the finished product, and ensures the appearance quality of the product. Distillation residues and mother liquor filter residues are fermented by bacillus subtilis to produce enzyme primary pulp, the comprehensive utilization rate of raw materials is greatly increased, and resource circulation is achieved.
Owner:HUBEI CHUTIANSHU PHARMA