4 results about "Betulinic acid" patented technology

The present application relates to the technical field of cosmetic raw materials, and particularly relates to a cosmetic composite raw material for removing acne spots and a preparation method thereof. The preparation method of the cosmetic composite raw material for removing acne spots comprises the following steps: preparation of betulinic acid-ostruthin co-assembled nanoparticles, double modification of mannose, preparation of retinol slow-release particles, and preparation of the cosmetic composite raw material. The present application realizes efficient acne spot removal through the synergy of multiple components. The core components, such as betulinic acid, have multiple anti-inflammatory and antibacterial effects, ostruthin inhibits melanin production, glutathione lightens old pigments, retinol and salicylic acid accelerate keratin metabolism, the co-assembly of betulinic acid-ostruthin nanoparticles improves bioavailability, modified mannose / epsilon-polylysine layer-by-layer embedding realizes retinol slow-release synergism, the synergy among the components enhances the effects of spot lightening and anti-inflammation, and the modified mannose can also repair the skin barrier, so that the effect of targeted treatment and barrier repair for removing acne spots is finally realized.

The application provides application of white birch acid in calcite inhibition. The molecular structure of the white birch acid contains functional groups such as hydroxyl, carboxyl and carbon six-membered ring, which are hydrophilic groups and solidophilic groups, have strong adsorption on calcite, make the white birch acid easy to be adsorbed with the calcite, and are not easy to be adsorbed with the fluorite ore. The excellent selectivity expands the floatability difference between the calcite and the fluorite ore, so that the selectivity of the fluorite ore flotation method based on the white birch acid is excellent, and the flotation effect is good. Compared with the existing inhibitors such as water glass, the white birch acid has stronger selectivity when used as the fluorite ore flotation inhibitor, and can obtain better flotation effect under the condition of smaller dosage, and the white birch acid is non-toxic and has small environmental pollution.

A COMPOSITION FOR TREATING KERATIN MATERIAL AND METHODS THEREOF The present disclosure provides a composition (A) comprising: a. oleanolic acid, its salts, solvates, or their mixtures thereof; b. ursolic acid, its salts, solvates, or their mixtures thereof; c. betulinic acid, its salts, solvates, or their mixtures thereof; and d. micromeric acid, its salts, solvates, or their mixtures thereof. The present disclosure further provides a rosemary extract and a composition (B). The present disclosure also provides a process for preparing the composition (A), the extract and methods thereof.

This invention discloses a betulinic acid derivative, its preparation method, and its uses. Using betulinic acid, a natural lupin-type pentacyclic triterpenoid, as the parent compound, a series of betulinic acid derivatives based on C-2 and C-3 position structural modifications were synthesized sequentially via oxidation and Claisen condensation reactions. These betulinic acid derivatives exhibit excellent α-glucosidase inhibitory activity. Their chemical structures differ significantly from existing clinical drugs, and their parent compounds are derived from natural products. This invention holds promise for overcoming the gastrointestinal adverse reactions and other drawbacks of traditional α-glucosidase inhibitors, providing new drug candidates for diabetes treatment. Furthermore, the raw materials for this invention are relatively widely available, facilitating subsequent scale-up production and process optimization, and possessing the potential for further development into clinical drug candidates.