The invention belongs to the technical field of
traditional Chinese medicine preparations, and discloses a retroauricular administration type sleep-promoting
traditional Chinese medicine compound composition and a preparation method thereof. The retroauricular administration type sleep-promoting
traditional Chinese medicine compound composition is prepared from
pericarpium citri reticulatae, fingered citron,
agastache rugosus, liquorice, lily, fried spina date seed, processed
polygala tenuifolia,
schisandra chinensis, poria with hostwood, platycladi seed, acanthopanax, cortex albiziae, rhizoma acori graminei, rhizoma anemarrhenae,
albizia flower and pseudo-
ginseng according to a
specific mass ratio. According to the preparation method disclosed by the invention, the
dissolution rate and the
transdermal absorption efficiency of active ingredients in the medicinal materials are remarkably improved by carrying out
cell wall breaking pretreatment on the prepared
polygala tenuifolia and / or the
schisandra chinensis, including
modes of enzymolysis, bacterium-
enzyme synergistic
fermentation and
plasma-assisted wall breaking. According to the preparation method, an
ethanol-water
mixed solution is used for extraction and
centrifugal separation, and a
medicine extracting solution is obtained. The composition can quickly and efficiently play a role in promoting sleep in a retroauricular administration manner, and has the comprehensive effects of soothing the nerves, stabilizing the mind, soothing the liver, relieving depression and promoting the circulation of heart and
kidney.