6 results about "Anthraquinone" patented technology

This invention belongs to the field of microbial technology, specifically disclosing a method for artificially cultivating *Anthraquinone longipes* containing camptothecin using bamboo shoot shell waste. The method involves inoculating *Anthraquinone longipes* into SKG medium for cultivation. The SKG medium consists of bamboo shoot shell powder with a solid-liquid ratio of 20:20 and MS medium with a concentration of 0.5 g / L. This invention is the first to achieve the artificial cultivation of *Anthraquinone longipes* fruiting bodies using waste bamboo shoot shells. Furthermore, the secondary metabolites of the cultivated fruiting bodies were evaluated, revealing that the fruiting bodies can produce camptothecin, thus enhancing the economic value of *Anthraquinone longipes* and providing a new pathway for the industrial production of camptothecin.

The application discloses a yellow organic dye, a preparation method thereof and application of the yellow organic dye in preparation of yellow spandex fibers, and belongs to the technical field of dyes and fiber preparation, and comprises the following steps: 1,5-dichloroanthraquinone, p-mercaptophenethyl alcohol, a carbonate and a dye solvent are added into a reaction together, hydrochloric acid is added to precipitate a product, the product is recrystallized with acetone, and the yellow organic dye is obtained. The yellow organic dye is dissolved in a solvent A, polyols and isocyanate are added, a catalyst is added or not, a reaction retarder is added or not, a chain extender is added or not, and a blocking agent is added or not, then the reaction is carried out, defoaming is carried out, dry spinning is carried out, and the yellow spandex fibers are obtained. In the application, the dye is connected to the spandex main chain through a covalent bond, the spandex fibers have a color, and the problems of difficult dyeing of the spandex fibers in the later stage, much wastewater and the like can be solved; the dye is combined with the spandex fibers through a chemical bond and is fixed in the high molecular chain, and has excellent dry and wet rubbing fastness and excellent migration resistance.

This invention relates to the application of anthraquinone I in the preparation of drugs for the prevention and treatment of type 2 diabetes. The method involves pulverizing the whole herb of *Patrinia scabiosifolia*, extracting it by reflux with ethanol, and concentrating under reduced pressure to obtain an extract. The extract is then sequentially extracted with equal volumes of petroleum ether, dichloromethane, and n-butanol. The dichloromethane layer is separated by silica gel column chromatography to obtain 10 fractions (Fr.1 to Fr.10). Fr.5 is further separated by ODS column chromatography, eluting with a methanol-water gradient to obtain 5 fractions (Fr.5-1 to Fr.5-5). Fr.5-4 is separated by Sephadex LH-20 column chromatography, and then purified by semi-preparative high-performance liquid chromatography to obtain anthraquinone I. The extraction method of anthraquinone I in this invention is simple and suitable for large-scale production. Anthraquinone I can inhibit α-glucosidase and can be used in the preparation of hypoglycemic drugs.

The application relates to the field of biological medicine, in particular to pharmaceutical application and a pharmaceutical composition of 1,8-diacetylrhefa. The application of 1.1,8-diacetylrhefa in the preparation of a drug for treating Alzheimer's disease mediated by mitochondrial autophagy; and a pharmaceutical composition, which is composed of a therapeutically effective amount of 1,8-diacetylrhefa and a pharmaceutically acceptable carrier. 1,8-diacetylrhefa can specifically activate the PINK1 / Parkin signal pathway, thereby promoting the removal of damaged mitochondria and restoring the organelle homeostasis in neurons. Experimental results show that in cell and animal models, it can effectively reduce the beta-amyloid level and improve the cognitive dysfunction of model animals, such as increasing the spontaneous alternation rate of Y maze, prolonging the passive avoidance test latency, thereby providing a candidate treatment scheme with disease modification potential for neurodegenerative diseases.