1353 results about "Photosens" patented technology

The invention provides a photosensitive resin composition containing a photobleaching aminomethyl anthracene photosensitizer and application thereof.The structural main body anthracene ring of the photosensitizer introduces an aminomethyl functional group to the 9th and / or 10th site: through introduction of the aminomethyl functional group, while the electron cloud density of polycyclic aromatic hydrocarbon is maintained, the maximum absorption wavelength is subjected to red shift, and the photosensitive resin composition is especially suitable for a 405nm illumination system; the initiation efficiency is obviously improved; the exposure energy is reduced; compared with an existing DBA type photoinitiator, the problem of alkoxy carbon-oxygen bond breakage caused by p-pi conjugation of DBA is avoided, generation of small molecule fragments is effectively inhibited, defects are reduced, and the yield is increased. In addition, compared with DPHA and DAcOA, the photosensitizer also shows better solubility and formula compatibility. The preparation method has the characteristics of simple preparation process and low cost, and can be widely applied to the photocuring fields of dry films, paints, coatings, printing inks, forming materials and the like.

The invention discloses a photodynamic inactivation parameter adjusting method based on hybrid fuzzy-PID control, relates to the technical field of parameter fuzzy control, and aims at the problem that photodynamic inactivation efficiency and aquatic organism safety in aquaculture are difficult to consider at the same time through multi-sensor fusion and environment prediction. Then, a fuzzy-PID self-adaptive putting technology is adopted to be coupled with an illumination strategy, and accurate matching of the photosensitizer dosage and the light intensity is achieved; water body fluctuation and pathogen diffusion are dealt with through real-time closed-loop and multi-scene collaborative scheduling; multi-dimensional index evaluation is utilized, reinforcement learning is introduced to carry out self-learning optimization, and putting and illumination parameters are continuously improved; and finally, the method is expanded to large-scale distributed control and cloud big data training, and efficient inactivation and flexible deployment can be kept in different breeding scenes. Pathogens can be effectively prevented from being rapidly diffused in an adverse environment, damage to aquatic animals caused by excessive accumulation of reactive oxygen species (ROS) is reduced, and meanwhile energy consumption and resource waste are reduced.

The invention discloses a full-biodegradable paper diaper breathable bottom film, and relates to the technical field of paper diaper production, and the full-biodegradable paper diaper breathable bottom film comprises the following components by weight: 45-55 parts of polylactic acid, 35-45 parts of a starch-based polymer, 10-12 parts of plant short fiber, 8-10 parts of bamboo fiber, 2-4 parts of a photosensitizer, 5-10 parts of polyvinyl alcohol, and 1-3 parts of lavender essential oil. According to the present invention, the starch-based polymer can enhance the biodegradability and the flexibility, the bamboo fiber can improve the water absorption and the natural antibacterial property, and can accelerate the degradation; the photosensitizer accelerates the degradation speed of the material under illumination, and the biodegradable material is adopted, so that the pollution to the environment is reduced, and the requirement of sustainable development is met.

Antibiotic for use in a method comprising systemically administering a photosensitive antibiotic to a subject having a microbial infection in a target tissue to provide a blood plasma concentration of the antibiotic in the subject; allowing the plasma or tissue concentration of the antibiotic increase to a predetermined level; and subjecting the target tissue to photodynamic therapy in order to increase the antimicrobial action of the antibiotic in the target tissue. With light activation the efficacy of the photosensitizer antibiotic can be enhanced, the spectrum of the microbial effect broadened and even an antiviral effect can be obtained. Generally, the present invention can be exploited when there is a need for enhancement of the local antimicrobial effect of antibiotics.

The invention discloses an optical fiber balloon catheter, and relates to the technical field of medical instruments. The optical fiber balloon catheter comprises a catheter main body, a balloon and a flow slowing component, the balloon is arranged at the far end of the catheter body, and medicine is arranged on the surface of the balloon. At least in the process of conveying the balloon to a target part, the flow slowing part is located on the receiving side, receiving fluid impact, of the balloon, and the flow slowing part is used for slowing down flushing of fluid to medicine on the surface of the balloon in the process; wherein when the optical fiber balloon catheter performs reverse motion relative to fluid, the welcoming side is the far-end side of the balloon; when the optical fiber balloon catheter moves in the same direction relative to fluid, the receiving side is the near-end side of the balloon. The structure of the optical fiber balloon catheter is improved, scouring of fluid to the balloon in the conveying process is relieved, and loss of the photosensitizer on the surface of the balloon in the conveying process is effectively reduced.

The invention provides a photosensitive resin composition containing an anthracene methyl quaternary ammonium salt photosensitizer and application of the photosensitive resin composition, a structural main body anthracene ring of the photosensitizer is introduced into methylene substituted by a quaternary ammonium group at a position 10 and / or a position 9, and an acid radical or halogen is adopted as an equilibrium anion; compared with a commercially available anthracene photosensitizer, the photosensitizer has excellent fat solubility and good water solubility through introduction of the quaternary ammonium salt on the premise that the photobleaching property is retained, great potential is brought to formula design of the photosensitive composition, and development waste in a later development process can be greatly reduced; the method can be widely applied to the photo-curing fields of dry films, paints, coatings, printing ink, forming materials and the like.

The preparation method comprises the following steps: synthesizing gold nanostars (GNS) by using a seed growth method, coating mesoporous cerium dioxide (mCeO2) by using a template method, and loading a photosensitizer indocyanine green (ICG), so as to form a nano enzyme diagnosis and treatment system with chemical activity, photoactivity and photothermal effects. In the system, the gold nanostars have a good photo-thermal effect due to the multi-branched structure of the gold nanostars; on one hand, the mesoporous cerium dioxide coated on the outer layer has a chemical effect due to the nano-enzyme effect, and on the other hand, the mesoporous structure of the mesoporous cerium dioxide can better load the photosensitizer indocyanine green. All the components have good stability and biological safety, also have peroxidase simulation activity and a drug loading function, can improve the level of reactive oxygen species (ROS) in a tumor microenvironment and load photosensitizer drugs, and have an excellent anti-tumor effect and small side effects.

The invention provides triazole anthracene methyl formate for a photosensitive resin composition, and relates to the field of photopolymerization. The invention also comprises a photosensitive resin composition containing the triazole anthracene methyl formate, a photosensitive dry film containing the triazole anthracene methyl formate, and applications of the photosensitive resin composition and the photosensitive dry film. The triazole formic acid anthracene methyl ester disclosed by the invention has photosensitivity, can be used as a photosensitizer in the photosensitive resin composition, can improve the adhesive force of the photosensitive resin composition on various metal surfaces, and has the characteristic of low migration; the method can be widely applied to the photo-curing fields of dry films, paints, coatings, printing ink, forming materials and the like.

The invention discloses a dual-mechanism antibacterial photosensitizer as well as a preparation method and application thereof, and relates to the technical field of biomedical photoelectric functional materials. The invention relates to a triphenylamine derivative, which can realize fluorescence imaging of bacterial or fungal infection by utilizing fluorescence characteristics, can generate active oxygen under illumination to play a photodynamic therapy role, is suitable for preparing photodynamic therapy preparations and developing antibacterial materials, and can also be applied to the fields of environment and public health and tumor treatment. The problems that an existing photosensitizer is insufficient in broad spectrum, different in fungus drug resistance mechanism, limited in single treatment effect and the like can be effectively solved, and the photosensitizer has wide application prospects.

The invention provides anthracene methylthiosalicylic acid for a photosensitive resin composition, and relates to the field of photopolymerization. The invention also comprises a photosensitive resin composition containing the anthracene methylthio-salicylic acid, a photosensitive dry film containing the anthracene methylthio-salicylic acid, and applications of the photosensitive resin composition and the photosensitive dry film. The anthracene methyl thiosalicylic acid has photosensitivity and can be used as a photosensitizer in the photosensitive resin composition; the migration characteristic is low; the photosensitive resin composition has good solubility in conventional monomers, and the degree of freedom of formula design of the photosensitive resin composition is greatly improved; the developing agent also has very good solubility in alkali liquor, so that developing garbage can be greatly reduced, and the product yield is improved; the adhesive force of the photosensitive resin composition on various metal surfaces can be improved; the method can be widely applied to the photo-curing fields of dry films, paints, coatings, printing ink, forming materials and the like.

The invention discloses an antibacterial film loaded with a fucoxanthin nano material and a preparation method of the antibacterial film. The antibacterial film is prepared by taking a nitrogen-rich hollow carbon material-fucoxanthin (NHC-FX) nano material as an antibacterial photosensitizer, chitosan as a substrate of a film and glycerol as a plasticizer of the film through a solution casting method. The antibacterial film disclosed by the invention is good in hydrophobicity and high in stability, can reduce transmission of ultraviolet light, and has a good photodynamic antibacterial effect. The antibacterial food packaging material can be used as an antibacterial food packaging material or a preservative film, can prevent food from being polluted by microorganisms, and can isolate damage of ultraviolet rays to the food.

The invention discloses an acid responsive nanoprobe as well as preparation and anti-tumor application thereof. The nanoprobe has a core-shell structure, takes a nanoparticle self-assembled by a polycation aggregation-induced emission (AIE) photosensitizer and functional nucleic acid as a core, and takes a hyaluronic acid modified metal polyphenol network as a shell. The nanoprobe utilizes the acid responsiveness and broad-spectrum absorption performance of the metal polyphenol network and the diagnosis and treatment advantages of the polycation AIE photosensitizer to realize the acid responsiveness'switch 'controllable diagnosis and treatment of the tumor nanoprobe. In a neutral environment, the fluorescence is weak, the generation of ROS is less, and the background noise signal of the nanoprobe and the toxicity of non-targeted tissues are reduced; in an acid environment, fluorescence is enhanced, the ROS yield is improved, and the treatment efficiency and the curative effect monitoring accuracy are improved. The nano diagnosis and treatment probe is ingenious in design and simple to prepare, and can realize PDT and gene therapy synergistic anti-tumor, in-situ real-time report of early tumor treatment effect and assistance in precise cancer treatment.

The invention discloses a composite film based on light-biological synergistic gradient degradation and a preparation method thereof, the composite film sequentially comprises a light response layer, a transition layer and a biological response layer from outside to inside, and the light response layer comprises a polycaprolactone matrix, a tetraphenylporphyrin iron photosensitizer and anatase type TiO2 nanorods; the transition layer is a gradient blend of polylactic acid and modified starch; the biological response layer comprises polyhydroxyalkanoate and bacterial cellulose nanofibers; through the design of the three-layer gradient structure and the construction of the bionic microchannel, the synergistic effect of light degradation, hydrolysis and biodegradation is realized; the composite membrane has excellent mechanical properties and environmental adaptability, the degradation period can be accurately regulated and controlled within 30-180 days, and the soil degradation rate within 60 days reaches 91% or above; the preparation method comprises the processes of electrostatic spinning, gradient co-extrusion and bacterial cellulose in-situ culture. The material can be widely applied to the fields of agricultural mulching films, food packaging and the like, and the problems that a traditional degradable film is poor in mechanical property and uncontrollable in degradation are solved.

The invention belongs to the technical field of medicines, and discloses photosensitizer-entrapped tumor cell membrane bionic metal organic framework nanoparticles as well as preparation and application thereof. The photosensitizer-entrapped tumor cell membrane biomimetic metal organic framework nanoparticles are prepared by adopting a tumor cell membrane biomimetic camouflage technology and coating the surface of the metal organic framework nanoparticles with the photosensitizer through repeated membrane extrusion or ultrasonic treatment. The preparation process is simple, the cost is low, and a complex synthesis process is not needed. The bionic nanoparticle disclosed by the invention has the functions of homologous targeting and immune escape, and is beneficial to prolonging the in-vivo circulation time and realizing higher tumor tissue targeting. In addition, the bionic nanoparticles can kill tumor cells through a photodynamic effect, and have the advantages of good therapy and low toxic and side effects.

A photosensitizer chimera targeting PD-L1 protein, and a preparation method therefor and a use thereof. The photosensitizer chimera is of an X-R-G structure, wherein X is a photosensitizer unit, R is a linker, G is a polypeptide unit targeting PD-L1 protein, the photosensitizer is a porphyrin photosensitizer, and the excitation light wavelength of the photosensitizer is longer than 550 nm; the molar absorption coefficient at the maximum absorption wavelength longer than the wavelength of 550 nm is greater than 1000 M -1cm-1; the quantum yield of a triplet state exceeds 0.01; the linker is selected from the following structural formulas, wherein the amino side of the linker is connected to the photosensitizer unit, the carboxyl side of the linker is connected to the polypeptide unit, and n is an integer of 0-50; the binding constant of the polypeptide and h-PD-L1 is less than 20 µm. Combination therapy of immune checkpoint blockade and cytotoxicity induced by the photosensitive chimera based on photodegradation of PD-L1 protein in PD-1 / PD-L1 can cause stronger immune response than monotherapy, and thus the photosensitive chimera has great potential in enhancing antitumor therapy.

The invention provides a photodynamic and chemotherapy synergistic antibacterial composite material, the composite material comprises an intermediate composite material and hyaluronic acid HA coating the outer side of the intermediate composite material, and the intermediate composite material takes a photosensitizer i-ZnPPOPs as a substrate and is loaded with calcium peroxide and gentamicin. The composite material has excellent bacteria targeting characteristic and antibacterial effect. Specifically, hyaluronic acid can target hyaluronidase secreted by bacteria so as to capture the bacteria, and then the intermediate composite material is transferred to the surfaces of the bacteria and interacts with negatively charged bacterial membranes. Then, the exposed biomass-based CaO2 is released and reacts with water to generate H2O2 and O2, so that oxygen deficit of the infected wound surface is relieved, generation of < 1 > O2 in the i-ZnPPOPs is effectively promoted, and the photodynamic antibacterial effect is further improved. Meanwhile, the released gentamicin can further improve the antibacterial efficiency of the chemotherapy.

The invention provides an aza-BODIPY molecule with NIR-II fluorescence emission and I-type photodynamic activity and a preparation method thereof. The aza-BODIPY molecule has good light absorption in a near-infrared (NIR) region, the emission peak of the aza-BODIPY molecule is prolonged to a near-infrared second region (NIR-II), and the aza-BODIPY molecule shows an ultrahigh NIR-II fluorescence quantum yield of 13%. Meanwhile, the photosensitizer prepared by adopting aza-BODIPY molecules can effectively generate I-type active oxygen species, namely superoxide anion free radicals, under the excitation of 808nm laser. On the basis, high-resolution tumor fluorescence imaging can be realized by utilizing NIR-II fluorescence of the aza-fluorine boron fluorescent sensitizer, and the aza-fluorine boron fluorescent sensitizer is used for accurate and efficient NIR-II fluorescence imaging mediated I-type photodynamic therapy of deep tumor tissues.

Method and apparatus for directing pulsed light beams at an in vivo treatment site to create thermoelastic expansion of tissue which generates ultrasonic pulse waves in the mega hertz range. One or more photosensitizers are applied to the treatment site. Further, the ultrasonic pulse waves either singly, or in combination with the pulsed light waves cause the activation of the photosensitizers to generate singlet oxygen at the treatment site.

The invention belongs to the technical field of biomedical nano material preparation, and provides defect-rich cobalt-zinc-tungsten hydrotalcite as well as a preparation method and application thereof. According to the preparation method disclosed by the invention, based on the controllability and defect engineering of two-dimensional layered double hydroxides (LDHs) main body laminate metal elements and interlayer anions, W < 6 + > / W < 5 + > and Co < 3 + > / Co < 2 + > conversion systems are introduced by regulating and controlling the influence rule of laminate metal composition, arrangement, density, orientation and etching conditions on the photodynamic activity of the LDHs; and when the defect-rich cobalt-zinc-tungsten hydrotalcite is used as the photosensitizer, the ROS yield is high. Through biological effect and metabolic behavior research, the defect-rich cobalt-zinc-tungsten hydrotalcite with good biocompatibility and excellent performance is selected, and a theoretical basis is provided for application of the defect-rich cobalt-zinc-tungsten hydrotalcite to treatment of HCM.

The invention designs and synthesizes a tetraphenyl ethylene covalent molecular cage with pyridine functionalization, and an AIE supermolecule photosensitizer is obtained through coordination and the synergistic effect of a subject and an object. The TPE unit enhances the photophysical properties of the photosensitizer and endows the photosensitizer with the AIE characteristic; the molecular cage and tetraphenylporphyrin are combined through a host and a guest, so that self-aggregation of porphyrin in water is further inhibited, ROS generation is promoted, and cancer cells are effectively killed through photocatalysis NADH oxidation assistance.

The invention belongs to the technical field of biological medicine, and discloses a bionic nano-particle suspension formulation based on orthoester compounds and a preparation method of the bionic nano-particle suspension formulation. The bionic nanoparticle suspension formulation comprises a liquid auxiliary material, a photosensitizer and bionic nanoparticles, wherein the photosensitizer and the bionic nanoparticles are dispersed in the liquid auxiliary material. According to the present invention, an orthoester compound represented by a formula I is adopted as a liquid auxiliary material, bionic nanoparticles and a photosensitizer are simultaneously introduced into OE to obtain the bionic nanoparticle suspension formulation having multiple antitumor mechanisms, the bionic nanoparticles are cancer cell membrane vesicle-coated nano-drugs, and the cancer cell membrane vesicle-coated nano-drugs can be prepared through a cancer cell membrane biomimetic technology, such that the cancer cell membrane vesicle-coated nano-drugs can be prepared into the bionic nanoparticle suspension formulation having multiple antitumor mechanisms; the homologous targeting function provided by the cancer cell membrane is utilized, and the active targeting property and cellular uptake of the nano-drug are remarkably improved. Formula I: # imgabs0 #

The invention relates to a copper phthalocyanine covalent organic framework material with photodynamic / chemical dynamic sterilization and a preparation method and application thereof, and belongs to the technical field of advanced functional materials and biological medicines. A covalent organic framework is synthesized by taking 4, 4 ', 4', 4 ''-tetra-(4-amino) copper phthalocyanine (CuTAPc) as a main structural unit, and the distance between photosensitizers can be limited, so that the self-aggregation quenching of the photosensitizers is reduced, and a good photodynamic effect is realized. Meanwhile, the copper ions consume glutathione overexpressed in the bacterial microenvironment, consumption of active oxygen is avoided, Fenton-like reaction is further triggered, toxic active oxygen is generated, chemical power synergistic treatment is achieved, the defect that the depth of light penetrating through the tissue is limited is effectively overcome, and a good treatment effect on deep tissue is achieved. A composite antibacterial film is further constructed based on the material. The multifunctional material has good stability and active oxygen generation capability, has good biological safety, and has huge potential in the fields of bacterial infection treatment, fruit and vegetable preservation and the like.

The invention provides UV white ink for specialty paper as well as a preparation method and application of the UV white ink. The UV white ink is prepared from the following raw materials in percentage by mass: 20 to 24 weight percent of polyurethane acrylic resin, 8 to 12 weight percent of epoxy acrylic resin, 8 to 12 weight percent of acrylic ester, 45 to 65 weight percent of titanium dioxide, 0.5 to 1.5 weight percent of wax powder, 5 to 7 weight percent of photosensitizer and 0.5 to 1.5 weight percent of heat stabilizer, wherein the molecular weight of the polyurethane acrylic resin is 20,000-100,000; the particle size of the titanium dioxide is less than 0.36 mu m, the particle size distribution is 0.25-0.36 mu m, and the density is 0.38-0.42 g / cm < 2 >. The UV white ink has the advantages that by adding the ultra-high molecular weight UV resin for improving the flexibility and dispersity and the auxiliaries into the formula, the folding resistance and the friction resistance of the white ink can be improved, the adhesive force of the UV white ink is improved, and meanwhile, the titanium dioxide with excellent performance is added, so that the covering rate and the whiteness of the UV white ink are very good.

A gold nanocluster of the formula Au16(RGDC)14, wherein RGDC is arginine-glycine-aspartic acid-cysteine, and methods for synthesis, are described. The gold nanocluster effectively produces Type I ROS and functions as photosensitizer, and has utility in applications such as, but not limited to, biomedical applications and photocatalysis. The gold nanocluster may be useful in photodynamic therapy (PDT) in cells and tissues for treating diseases such as certain cancers.

The invention relates to the technical field of dry films, in particular to a photosensitive resin composition, a photosensitive dry film and a preparation method of the photosensitive dry film. Comprising alkali-soluble resin, a photopolymerizable monomer with at least one vinyl unsaturated group, a photosensitizer and other additives, and the alkali-soluble resin at least comprises a nitrogen-containing heterochain or nitrogen heterocyclic ring monomer chain segment group; the alkali-soluble adhesive resin containing aza-chain or azacyclo-containing monomer chain segment groups is prepared by introducing an aza-chain or azacyclo-containing monomer, such as a monomer containing primary amine, secondary amine, tertiary amine, quaternary ammonium salt, pyridines, imidazoles and other groups, into alkali-soluble resin, and is used for improving the adhesive force and binding force between the resin and the surfaces of metals such as copper and the like; therefore, the resolution and adhesion capability of the photosensitive resin composition or the photosensitive dry film is improved.

Method and kit for topical treatment of a skin infection, in particular of superficial skin infections, caused by Staphylococcus aureus. The method comprises the steps of applying a photosensitizer to at least a part of the skin affected by the infection, and subjecting said part of the skin to first photons with a majority energy between 2.8 eV and 3.5 eV at a first energy level; and second photons with a majority energy between 1.24 eV and 1.65 eV at a second energy level, the ratio between the first and the second energy levels being in the range from about 10:1 to 2:1. By the method efficient treatment of Staphylococcus aureus infections can be achieved without the administration of topical antibiotics.

The invention discloses a multifunctional nano delivery system based on targeted ferritin as well as a preparation method and application of the multifunctional nano delivery system. According to the system, traditional Chinese medicine active ingredients, namely neogambogic acid GNA, a photosensitizer Ce6 and ferritin targeting peptide HKN15 are integrated through a self-assembly technology, a synergistic treatment system integrating photodynamic therapy PDT and ferroptosis induction is constructed, and the treatment effect on non-small cell lung cancer NSCLC can be remarkably enhanced. According to the nano delivery system, precise targeting of a tumor site is achieved through the ferritin targeting peptide HKN15, and a double anti-tumor mechanism is formed by utilizing the photodynamic effect of the photosensitizer Ce6 and the ferroptosis induction effect of GNA. The preparation process is based on a molecular self-assembly principle, and has the advantages of high tumor accumulation efficiency, low system toxicity, remarkable tumor inhibition effect and the like, and an innovative solution is provided for precise treatment of the non-small cell lung cancer.

According to the OLED diagnosis and treatment integrated system and method for photodynamic precise treatment, treatment light field customization and regulation and control functions based on an OLED are achieved, light field distribution is regulated and controlled through fluorescence feedback, the optimal treatment effect is achieved, and preoperative detection and intraoperative monitoring of photosensitizer fluorescence and autofluorescence are supported. The phototherapy module uses an OLED flexible panel to carry out phototherapy, an OLED is divided into a plurality of independent small square blocks, each small square block is provided with a hole for embedding a fluorescent module, and other parts are used for phototherapy; the fluorescence module acquires a fluorescence signal at the focus; the user module communicates with the control module through the communication module; the control module acquires user module information and fluorescence signals, controls the driving module to realize light field customization and regulation, judges a focus range according to fluorescence distribution, adjusts illumination intensity according to fluorescence intensity, and realizes precise treatment of the focus; the power supply module supplies power to the diagnosis and treatment integrated system.

The invention relates to the technical field of photoinitiators, and provides a triplet-triplet energy transfer (TTET) free radical I type photoinitiation system, a photocuring composition and application thereof. The system comprises a boron dialkylated dipyrromethene free radical I type photoinitiator and a long wave absorption photosensitizer, the photosensitizer is preferably an osmium (II) complex, and the mass ratio of the photosensitizer to the photoinitiator is preferably 1: 5-1: 200. Under the irradiation of a 650-750 nm light source (preferably a 690 nm LED), the photosensitizer enters a triplet state through intersystem crossing and generates TTET to the photoinitiator, so that the photoinitiator is uniformly split in the triplet state to generate free radicals, thereby initiating polymerization / cross-linking curing of monomers such as (methyl) acrylate and the like. The embodiment shows that the double bond conversion rate of the TPGDA can reach more than 80% within 10 minutes under the conditions of LED at 690 nm and 80 mW / cm < 2 >.

The invention relates to the technical field of adhesives, in particular to a flexible circuit board covering film and a preparation method thereof.The covering film is composed of a release film, a photo-thermal dual-curing composition and a polyimide film from top to bottom; the photo-thermal dual-curing composition is prepared from the following components in parts by weight: 80 to 125 parts of acrylic acid prepolymer, 8 to 25 parts of benzoxazine-novolac epoxy resin, 0.1 to 10 parts of photoinitiator, 0.1 to 5 parts of photosensitizer and 10 to 100 parts of solvent I. Due to the existence of the photo-thermal dual-curing composition, the peel strength of the cover film after photo-curing and thermal curing reaches 1.4 N / mm; the benzoxazine-novolac epoxy resin is applied to the cover film of the flexible circuit board, so that the cover film has acid resistance and high temperature resistance; by controlling the glass-transition temperature of the acrylic prepolymer, the requirements of high peel strength and high weather resistance of the cover film are met at the same time, so that the properties of the cover film in all aspects reach a balanced state.