Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

3results about How to "Maintain long-term" patented technology

A negative pressure wound drainage device for various chronic wound exudates

PendingCN122582394Aefficient suctionavoid mechanical damage
This invention relates to the field of medical device technology, and in particular to a negative pressure drainage device for various chronic wound exudates. It includes a disposable drainage bag, a dressing, and a frame for connecting the disposable drainage bag and clamping it onto a hospital bed. It also includes a micro-negative pressure drainage drive unit located on the bottom side of the clamping unit to generate negative pressure inside the disposable drainage bag; and a fastener, a threaded structure, installed at the bottom of the frame, which is also connected to a moving plate via a transmission component. Through the cooperation of the fastener, transmission component, and moving plate, the micro-negative pressure drainage drive unit organically integrates the frame fixing operation with the negative pressure generation process. When the fastener is tightened and fixed to the hospital bed, it simultaneously drives the moving plate to reset and applies tension to the fixing spring, causing the first clamping plate to displace away from the second clamping plate, thereby pulling the drainage bag to form an outward expansion deformation, creating a continuous and stable micro-negative pressure environment inside the bag.
Owner:BEIJING SHIJITAN HOSPITAL CAPITAL MEDICAL UNIVERSITY

Selective laser melting device for forming die machining

The invention discloses a selective laser melting device for forming die machining, and relates to the technical field of forming die machining, a laser is used for machining powder, a feeder conveys the powder to a lifting table, and a recovery bin is used for receiving the powder recovered by a recovery device; the lifting table, the feeder and the recovery bin are sequentially connected, the laser is arranged over the lifting table, a recovery device is arranged on the driving part, the driving part can drive the recovery device to move to the position above the lifting table, and the recovery device is used for recovering powder on the lifting table. By arranging the scraping plates, the servo motor and the fan, after mold machining is completed, the scraping plates can be accurately controlled to be close to one another by means of cooperative operation of the servo motor, the two-way screw rod, the sliding block and the air cylinder, a suction opening is formed in the bottom of each scraping plate, and residual metal powder in the machine body can be efficiently sucked and collected in cooperation with the fan; tediousness and low efficiency of manual cleaning are avoided, the labor cost is saved, the cleaning process is accelerated, and the overall machining efficiency is improved.
Owner:JIANGSU UNIV

A method for preparing articular cartilage organoids, a bio-ink encapsulating articular cartilage organoids, the preparation method thereon, and their applications.

PendingCN122081206AObvious cartilage-bone biological interfaceMaintain long-termAdditive manufacturing apparatusSkeletal/connective tissue cellsDocetaxelDrug additive
This invention relates to the field of organoid bioprinting technology, and discloses a method for preparing articular cartilage organoids, a bio-ink for encapsulating articular cartilage organoids, the preparation method thereon, and their applications. The preparation method includes: pretreating the raw material to be cultured in a basal culture medium containing a nanomedicine additive, wherein the nanomedicine additive chemically comprises mesoporous silica nanoparticles loaded with docetaxel and polyethyleneimine modified on the mesoporous silica nanoparticles; culturing the pretreated raw material in a cartilage organoid induction culture medium containing docetaxel; wherein the raw material to be cultured contains bone marrow mesenchymal stem cells. The articular cartilage organoids prepared by this method have a distinct cartilage-bone bio-interface, and the pretreatment process can help maintain the long-term phenotype of the cartilage organoids by inhibiting endochondral ossification during their development.
Owner:SHANGHAI NINTH PEOPLES HOSPITAL SHANGHAI JIAO TONG UNIV SCHOOL OF MEDICINE