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200results about How to "Good light stability" patented technology

High-elasticity shoe material and preparation process thereof

The invention belongs to the technical field of shoe materials, and particularly relates to a high-elasticity shoe material and a preparation process thereof. The high-elasticity shoe material comprises the following components in parts by weight: 70-80 parts of thermoplastic polyurethane elastomer; 10 to 20 parts of an ethylene-vinyl acetate copolymer; 15 to 20 parts of an ethylene-octylene copolymer; 10 to 15 parts of nitrile rubber; 8-10 parts of a composite antibacterial agent; 2-4 parts of a foaming agent; 0.6-1 part of zinc oxide; 1-2 parts of an antioxidant; 10-15 parts of a composite filler; the components are subjected to a blending foaming process to prepare the shoe material which is moderate in hardness, light in weight and high in elasticity, and the prepared shoe material also has good strength, wear resistance, yellowing resistance, antibacterial property and flame retardance.
Owner:WENZHOU ZHIBO SHOE MATERIALS CO LTD

Near-infrared two-region aggregation-induced emission material as well as preparation method and application thereof

The invention discloses a high-efficiency near-infrared two-region aggregation-induced emission material, a preparation method thereof and application of the high-efficiency near-infrared two-region aggregation-induced emission material in bimodal surgical navigation. According to the molecular structure, the organic near-infrared two-region material with an intramolecular charge transfer characteristic is constructed by taking thionaphthalene tetracarboxylic acid diimide as an electron acceptor group and tetraphenylethylene as a molecular rotor and an electron donor unit. By expanding the length of a pi conjugate fragment and introducing an isotope effect, the oscillator strength can be improved, and high-frequency vibration can be inhibited, so that the radiative transition rate of molecules is promoted, and the non-radiative transition rate is inhibited. The nanoparticles prepared from the aggregation-induced emission material have the advantages of high brightness, large Stokes shift and good light stability, and have an excellent effect in bimodal imaging guided mouse in-situ breast cancer and sentinel lymph node operation excision.
Owner:THE CHINESE UNIV OF HONG KONG (SHENZHEN)

Aggregation-induced emission molecule, nano motor, preparation method and application

The invention provides an aggregation-induced emission molecule, a nano motor and a preparation method and application of the aggregation-induced emission molecule, the aggregation-induced emission molecule is used for near-infrared emission, has photo-thermal properties, and has the characteristics of near-infrared II region luminescence, heat production and good light stability; the nano motor is prepared by taking an asymmetric double-mesoporous nano material with different pore diameters as a support material and selectively loading aggregation-induced emission molecules on one side of the support material with a larger pore diameter; under the irradiation of near-infrared light, the aggregation-induced emission molecules with the photothermal effect can form a non-uniform thermal gradient to push the self-thermophoresis movement of the nano motor; tumor sites can be diagnosed and reported under the mediation of near-infrared II region imaging; through the photo-thermal effect, the motor can destroy tumor interstitial cells and degrade tumor matrix components; and in combination with autothermophoresis, blood vessels can be penetrated, so that penetration to the deep layer of the tumor can be realized.
Owner:SHENZHEN LONGGANG DISTRICT PEOPLES HOSPITAL

Aggregation-induced emission microspheres with colorimetric-fluorescence double signals as well as preparation method and application of aggregation-induced emission microspheres

The invention discloses aggregation-induced emission microspheres with colorimetric-fluorescence double signals as well as a preparation method and application of the aggregation-induced emission microspheres. The aggregation-induced emission microsphere comprises a carboxyl polystyrene microsphere and an aggregation-induced emission dye embedded in the carboxyl polystyrene microsphere, the aggregation-induced emission microsphere has colorimetric-fluorescence double signals, is red under natural light, has strong absorption at 600nm, shows high luminous efficiency at 725nm, not only effectively avoids the interference of biological autofluorescence and reduces background interference, but also has good light stability and photobleaching resistance, and can be used for preparing the aggregation-induced emission microsphere. And due to the high molar extinction coefficient, the colorimetric and fluorescent double-signal output capability is realized at the same time. In addition, the aggregation-induced emission microspheres are high in reproducibility in the preparation process, have the potential of large-scale synthesis and meet the requirements of industrial batch production.
Owner:GUANGZHOU MEDICAL UNIV

Highly oil-proof and water-proof fluorine-containing composition and application thereof in coating

The invention relates to the technical field of coating preparation, in particular to a highly oil-proof and waterproof fluorine-containing composition and application thereof in coatings, the fluorine-containing composition comprises the following chemical components by weight: 70-80 parts of a resin mixture, 2-5 parts of diisocyanate, 5-8 parts of a modified titanium dioxide filler and 10-15 parts of modified glass flakes, the resin mixture comprises fluorinated hydroxyl acrylic resin and urethane acrylate, and the mass ratio of the fluorinated hydroxyl acrylic resin to the urethane acrylate is (3-5): 1. The resin mixture, the modified titanium dioxide filler and the modified glass flakes form a stable composite structure through chemical bonding and physical effects, and finally the fluorine-containing composition shows excellent waterproof and oil-proof performance and good mechanical strength.
Owner:ZHEJIANG HUALIN BIOTECHNOLOGY CO LTD

Flexible high-hydrophobicity self-luminous life jacket and preparation method thereof

The invention belongs to the technical field of 3D printing and flexible high-hydrophobicity self-luminous life jackets, and particularly relates to a flexible high-hydrophobicity self-luminous life jacket and a preparation method thereof. A self-luminous waterborne polyurethane emulsion of a hydrophobic modified energy-storage long-afterglow luminescent material is synthesized, the prepared self-luminous waterborne polyurethane emulsion is used for coating and post-processing a thermoplastic polyurethane elastomer (TPU) flexible life jacket part formed by SLS, and a luminous coating permeates into micro-gaps in the surface of the TPU part and is attached to the surface. And a firmly attached self-luminous coating is formed after curing, so that the hydrophobic property of the TPU life jacket product is obviously improved, and the self-luminous function in a dim and dark environment is also realized. The problems that a traditional fluorescent material is low in luminous intensity, incapable of continuously emitting light, poor in water resistance and the like are solved, and excellent high-hydrophobicity self-luminous performance is obtained on the premise that the original SLS forming process characteristics of the TPU life jacket are not changed and the mechanical property of the TPU life jacket is reserved.
Owner:OECHSLER PLASTIC PROD TAICANG +1

Preparation method and application of double-response controlled-release pesticide

The invention provides a preparation method and application of a double-response type controlled-release pesticide. The method comprises the following steps: S1, preparing modified biochar; s2, preparing a drug carrier by using the modified biochar; and S3, preparing the double-response controlled-release pesticide by using the drug carrier. The problems that an existing controlled-release pesticide cannot meet the controlled-release function easily, the preparation process is complex, and large-scale preparation is difficult are solved.
Owner:TARIM UNIV

Preparation method and application of polyhexamethylene biguanide hydrochloride / magnolol co-assembled anti-ultraviolet nano preparation

The invention discloses a preparation method and application of a polyhexamethylene biguanide hydrochloride / magnolol co-assembled anti-ultraviolet nano preparation. The preparation method of the polyhexamethylene biguanide hydrochloride / magnolol co-assembled anti-ultraviolet nano pesticide preparation comprises the following steps: dissolving polyhexamethylene biguanide hydrochloride in deionized water to obtain a polyhexamethylene biguanide hydrochloride solution, dissolving magnolol in an alkaline aqueous solution to obtain a magnolol solution, and adding the magnolol solution into the polyhexamethylene biguanide hydrochloride solution to obtain the polyhexamethylene biguanide hydrochloride / magnolol co-assembled anti-ultraviolet nano pesticide preparation. The preparation method comprises the following steps: slowly dropwise adding a magnolol solution into a polyhexamethylene biguanide hydrochloride solution, stirring in a dark place at a certain temperature, centrifuging, discarding supernate, freeze-drying and precipitating to obtain powder, and dissolving the powder into deionized water to obtain the polyhexamethylene biguanide hydrochloride / magnolol co-assembled anti-ultraviolet nano pesticide preparation. The nano preparation is prepared by a co-assembly method in water, and has better ultraviolet resistance. Compared with an existing method, the preparation method is simple in condition, convenient to operate and low in cost.
Owner:BEIJING UNIV OF CHEM TECH

Near-infrared second-region cyanine dye molecule, preparation method and application

The invention relates to the technical field of organic functional materials, in particular to a near-infrared second-region cyanine dye molecule as well as a preparation method and application thereof, the structural formula of the near-infrared second-region cyanine dye molecule is shown as a formula I or a formula II: # imgabs0 #, the cyanine dye molecule is modified by benzopyranium, the excitation wavelength and the fluorescence emission wavelength of the near-infrared second-region cyanine dye molecule both reach the near-infrared second region, and the near-infrared second-region cyanine dye molecule is a near-infrared second-region cyanine dye molecule. Strong absorption and emission are shown in a near-infrared second region, and the Stokes shift is greater than 50nm; the synthetic method of the fluorescent dye is simple, raw materials are easy to obtain, and the yield is high; the cyanine dye disclosed by the invention is excellent in photo-thermal stability and good in photo-thermal imaging effect, has a good phototherapy effect and has a great potential application prospect in the field of tumor treatment.
Owner:YUNNAN NORMAL UNIV

Near-infrared small-molecule fluorescent dye with pentadecanedioic conjugated chain as well as preparation method and application of near-infrared small-molecule fluorescent dye

The invention relates to a near-infrared small-molecule fluorescent dye with a pentadecamethine conjugated chain and a preparation method and application thereof, the near-infrared small-molecule fluorescent dye has a structure as shown in a general formula A, and is a novel dye matrix based on two benzoindole structures connected by a pentadecamethine chain, the functional dye molecule with the absorption and emission peak wavelength in the near-infrared region is obtained through regulation and control of substituent groups on a parent structure, and different substituent groups can be introduced to a fifteen-membered methine chain and an indole N atom. The absorption and emission wavelength is in a near-infrared region of 1100-1300nm, and the material has the characteristics of high brightness, excellent light stability, low cytotoxicity, simplicity and convenience in synthesis, easiness in structure modification and the like. After water-soluble modification, the polymer can be widely applied to the biomedical fields of tumor targeting imaging, living body angiography and the like. General formula A # imgabs0 #
Owner:SHANGHAI JIAOTONG UNIV

AIE fluorescence immunochromatography test strip for detecting toxoplasma gondii antibody as well as preparation method and application of AIE fluorescence immunochromatography test strip

The invention discloses an AIE fluorescence immunochromatography test strip for detecting a toxoplasma gondii antibody as well as a preparation method and application of the AIE fluorescence immunochromatography test strip, and belongs to the technical field of production of veterinary biological diagnosis products. The test strip provided by the invention comprises a bottom plate, a sample pad, a combination pad, a nitrocellulose membrane and a water absorption pad, wherein the sample pad, the combination pad, the nitrocellulose membrane and the water absorption pad are bonded on the bottom plate in an end-to-end connection manner; the combination pad is coated with AIE microsphere labeled protein; the nitrocellulose membrane contains a detection line T and a quality control line C; the test strip prepared by adopting a double-antigen sandwich antibody detection method can be used for detecting serum antibodies in animal bodies such as pigs, cats and the like. Compared with a colloidal gold test strip on the market, the colloidal gold test strip has the advantages that the sensitivity is improved by 32 times, the batch-to-batch difference is less than 5%, the test performed by adopting 40 parts of pig serum and 30 parts of cat serum shows that the specificity, the stability and the accuracy are excellent, the operation is simple, the cost is low, and an accurate result can be obtained only in 10 minutes; and a rapid and effective detection method is provided for epidemiological investigation and disease diagnosis.
Owner:SHANXI AGRI UNIV

Preparation method and application of porous GelMA microneedle for delivering AIE molecules based on HSF derived exosome

The invention discloses a preparation method and application of a porous GelMA microneedle for delivering AIE molecules based on HSF derived exosome. The preparation method comprises the following steps: S1, preparing TTMN molecules; s2, dispersing DPPC and Chol in chloroform, performing water bath evaporation at 50 DEG C to form a thin film, hydrating the thin film in PBS, incubating to enable DPPC and Chol to form a liposome structure again, and uniformly dispersing TTMN molecules in the liposome structure to obtain TL; s3, extracting an exosome from the HSF cells; s4, loading the TL into the exosome by utilizing an electroporation technology, so as to obtain TE; s5, preparing the GelMA; and S6, mixing the GelMA with the TE, so that the TE is uniformly dispersed in the GelMA to obtain a mixed solution, injecting the mixed solution into a microneedle mold, and irradiating with 405nm laser to obtain the porous GelMA microneedle. According to the invention, high-efficiency treatment of hypertrophic scars is realized, and the system has a remarkable drug delivery effect, an innovative photodynamic therapy, a high-efficiency scar tissue remodeling effect and good biological safety and stability, and has important clinical application value and market prospect.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Sodium alginate-based polyacrylamide hydrogel and preparation method thereof

The invention relates to the technical field of high polymer chemical polymerization, in particular to sodium alginate-based polyacrylamide hydrogel and a preparation method thereof. The sodium alginate-based polyacrylamide hydrogel is prepared from the following components in parts by mass: 10 to 20 parts of acrylamide, 10 to 15 parts of sodium alginate, 3 to 7 parts of modified montmorillonite, 1 to 3 parts of nano titanium dioxide, 0.3 to 0.9 part of anhydrous calcium chloride, 0.1 to 0.5 part of a cross-linking agent, a photoinitiator and tetramethylethylenediamine. The invention provides a sodium alginate-based polyacrylamide hydrogel and a preparation method thereof, and aims to solve the problems of poor mechanical properties and poor heat resistance of sodium alginate-acrylamide composite gel in related technologies.
Owner:ANHUI TIANRUN FUNCTIONAL POLYMER ENG RES CO LTD

Nerve-targeted imaging nano fluorescent probe constructed by near-infrared two-region aggregation-induced emission material and NP41 polypeptide as well as preparation method and application of nerve-targeted imaging nano fluorescent probe

The invention relates to a nerve-targeted imaging nano fluorescent probe constructed by a near-infrared two-region aggregation-induced emission material and NP41 polypeptide as well as a preparation method and application of the nerve-targeted imaging nano fluorescent probe, belongs to the technical field of medical image contrast agents, and particularly relates to a nerve-targeted imaging nano fluorescent probe constructed by combining a near-infrared two-region fluorescent material TTB with AIE characteristics and a nerve-targeted peptide NP41. The invention also relates to a preparation method of the fluorescent probe and application of the fluorescent probe in long-term continuous imaging of central and peripheral nerve living bodies.
Owner:FUDAN UNIVERSITY

Composition containing recombinant human nerve growth factor and application and ophthalmic preparation thereof

The invention discloses a composition containing a recombinant human nerve growth factor, application of the composition and an ophthalmic preparation. The composition is prepared from the following components in parts by weight: 0.005 to 1 part of recombinant human nerve growth factor, 20 to 70 parts of trehalose, 5 to 30 parts of mannitol and 1 to 13 parts of polyvinyl alcohol. The trehalose, the mannitol and the polyvinyl alcohol are compounded with the recombinant human nerve growth factor, so that the stability of the recombinant human nerve growth factor can be remarkably improved, and the loss of pharmacological active ingredients of the ophthalmic preparation in the preparation, transportation and long-term storage periods is reduced, so that the medication safety and the treatment effect are ensured; and the recombinant human nerve growth factor in the ophthalmic preparation is good in stability, so that the clinical requirements of patients with eye diseases can be better met.
Owner:KERUN BIOPHARM

Dye-sensitized rare earth up-conversion luminescent nano material as well as preparation method and application thereof

PendingCN121930832AGood water dispersibilityBlock penetration and quenchPhotodynamic therapyMaterial analysis by optical meansPhoto stabilitySinglet oxygen
The invention relates to the technical field of nano materials and biomedical engineering, and discloses a dye-sensitized rare earth up-conversion luminescent nano material as well as a preparation method and application thereof. The dye-sensitized rare earth up-conversion luminescent nano-material comprises a rare earth doped up-conversion nano-particle core, an unsaturated fatty acid salt self-assembled shell layer and a near-infrared dye modified on the surface of the rare earth doped up-conversion nano-particle. The unsaturated fatty acid salt coating layer endows the material with excellent water dispersibility through a hydrophilic group; a hydrophobic chain segment and an unsaturated double bond can effectively block water and oxygen permeation and quench singlet oxygen, so that the photobleaching half-life period of the material is increased by 86.7 times or more compared with that of a conventional coating material, and the light stability is excellent; the material successfully realizes efficient up-conversion luminescence under excitation of a low-power near-infrared light emitting diode (NIR LED, the power density of which can be as low as 100mW / cm < 2 >), and thoroughly gets rid of dependence on a high-cost and high-risk laser.
Owner:GUANGDONG OCCUPATIONAL DISEASE PREVENTION HOSPITAL +1

Fused ring tin porphyrin photosensitizer with high singlet oxygen sensitization efficiency and photothermal effect

The invention discloses a fused ring tin porphyrin photosensitizer with high singlet oxygen sensitization efficiency and photothermal effect, and relates to the technical field of biological medicine. The invention provides a structural general formula and a preparation method of a fused ring tin porphyrin photosensitizer. According to the invention, the photosensitizer is endowed with strong absorption capacity in an NIR region through an isoquinoline fused ring on the periphery of porphyrin, < 1 > O2 sensitization activity and photothermal effect of the photosensitizer under light excitation are promoted through metal tin coordination in a parent nucleus, and an efficient photodynamic / photothermal synergistic killing effect on 4T1 cells of a mouse breast cancer cell line under NIR light irradiation is realized; the problems of poor light stability, reduced photosensitive activity and the like in the prior art are effectively solved.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Ratio fluorescence sensing system based on aggregation-induced emission and application thereof

The invention relates to H2S detection, in particular to an aggregation-induced emission-based ratiometric fluorescence sensing system and application thereof.Penicillamine is used as a ligand to synthesize gold-copper nano-clusters (Pen-Au / CuNCs) and tetraphenylethylene modified hollow mesoporous silica (TPE-NH2-HMSNs) of an amino ligand, and the Pen-Au / CuNCs and the tetraphenylethylene modified hollow mesoporous silica are combined to successfully construct an efficient ratiometric fluorescence sensing platform (Au / CuNCs and HMSNs). The sensor is used for selectively detecting H2S, and two analysis methods of solution sensing and solid portable sensing are established. Compared with other methods for detecting H2S reported before, the method provided by the invention has a lower detection limit (0.147 [mu] M). In addition, a novel portable hydrogel bead fluorescence detection device is developed by utilizing color change, and quantitative visual detection of H2S is realized by combining with a smart phone.
Owner:CHINA PHARM UNIV

Composition with anti-aging effect as well as preparation method and application thereof

The invention discloses a composition with an anti-aging effect and a preparation method and application thereof, and belongs to the technical field of cosmetics. The composition is prepared by compounding a traditional Chinese medicine active component, a moisturizing and permeation promoting component and a repairing and anti-aging auxiliary component, and the traditional Chinese medicine active component is composed of three zymolytes and three fermentation extracts which are respectively prepared from six medicinal and edible traditional Chinese medicine raw materials through differentiated composite enzymolysis and probiotic anaerobic fermentation processes. The problems that traditional Chinese medicine extracts are low in transdermal absorption rate, poor in bioavailability and insufficient in cosmetic system stability are solved, active ingredients are small-molecularized through process optimization, a multi-target synergistic anti-aging system is formed by matching with functional components, the anti-aging and repairing composition has excellent anti-aging and repairing effects, physical and chemical stability and skin safety, and the anti-aging and repairing composition has a good application prospect. The composition is suitable for various skin types and can be widely applied to preparation of anti-aging repair cosmetics.
Owner:SHANGHAI JIAYU BIOLOGICAL TECH CO LTD +1

Application of gold cluster fluorescent probe in detection of hematopoietic stem cells of radiation-damaged animals

The invention discloses application of a gold cluster fluorescent probe in detection of hematopoietic stem cells of radiation-damaged animals, and belongs to the technical field of nano-drugs. In order to solve the technical problem that in the prior art, accurate detection of radiation-damaged animal hematopoietic stem cells is difficult, the invention provides application of a gold cluster fluorescent probe in detection of radiation-damaged animal hematopoietic stem cells, a gold cluster fluorescent molecule is composed of an Au atom, other metal atoms M and an outer ligand L, coupling the gold cluster fluorescent molecule with an antibody through a chemical cross-linking method to prepare a gold cluster fluorescent probe coupled with the antibody; the gold cluster fluorescent probe shows good biocompatibility, relatively strong photobleaching resistance, good light stability, high sensitivity and high specificity, has the targeting characteristic of hematopoietic stem cells, can be applied to detection and monitoring of hematopoietic stem cells in vivo, and can be applied to detection and monitoring of hematopoietic stem cells in vivo. And detecting the residual volume of the hematopoietic stem cells after radiation injury and evaluating the injury condition.
Owner:ACADEMY OF MILITARY MEDICAL SCIENCES

Preparation method and application of type i composite photosensitizer with hydrogen sulfide detection performance

This application relates to the biomedical field and discloses a method for preparing a type I composite photosensitizer with both hydrogen sulfide detection capabilities and its uses. The invention synthesizes a triphenylamine derivative TPAB with an A-π-D-π-A conjugated structure using TPA-CHO and MN as monomers via a Schiff base reaction, and further incorporates Cu... 2+ By introducing TPAB molecules, a stable metal complex photosensitizer is formed through coordination bonds. This application presents the functional composite photosensitizer TPAB-Cu. 2+ Characterized primarily by the generation of type I ROS, it exhibits highly efficient photodynamic bactericidal activity in hypoxic environments infected with drug-resistant bacteria. Furthermore, this functional molecule can be used to detect hydrogen sulfide levels in the microenvironment of drug-resistant bacterial infections, enabling early warning and real-time monitoring of the treatment process. This solves the technical problems of strong oxygen dependence of photosensitizers and insufficient sensitivity and specificity in response to the microenvironment of drug-resistant bacterial infections in existing photodynamic therapies.
Owner:SHANGHAI SONGJIANG DISTRICT CENTRAL HOSPITAL

Energy-saving fireproof durable copper alloy wire

The invention belongs to the technical field of wire manufacturing, and discloses an energy-saving fireproof durable copper alloy wire, which comprises a sheath and a conductor, and the sheath comprises the following components: 95-98 parts of polyethylene raw material; 1-3 parts of a composite antioxidant; 1-3 parts of a flame retardant; the composite oxidizing agent comprises aluminum oxide-magnesium oxide-composite xerogel and a hindered phenol antioxidant. The invention has the following effects: the hindered phenol antioxidant is small in molecular weight and easy to volatilize, so that the aluminum oxide-magnesium oxide-composite xerogel is researched and prepared, and the novel metal gel material has a pore structure and a large number of active groups, can adsorb, constrain and limit the volatilization of the hindered phenol antioxidant, and also has the advantages of low cost and high efficiency. The anti-oxidation effect of the hindered phenol antioxidant is not affected, volatilization of the hindered phenol antioxidant is effectively reduced when the electric wire works, especially works in a high-temperature environment, and the effects of aging resistance, durability, low manufacturing cost and industrial application and popularization value are achieved.
Owner:HANGZHOU DIBO METAL MATERIALS

Novel salt of imidazo [1, 2-a] pyridine compound, crystal form and preparation method thereof

In the novel salt of the imidazo [1, 2-a] pyridine compound, the crystal form thereof and the preparation method of the novel salt of the imidazo [1, 2-a] pyridine compound, the novel salt of the imidazo [1, 2-a] pyridine compound is azetidine-1-yl {8-[(2, 6-dimethyl benzyl) amino]-2, 3-dimethyl imidazo [1, 2-a] pyridine-6-yl} ketone citrate.
Owner:JEIL PHARM CO LTD +1

Ultra-high molecular weight polyethylene powder additive adding device

The utility model provides an ultra-high molecular weight polyethylene powder additive adding device which comprises an exhaust fan, an additive feeding hopper, an additive storage bin, a weightlessness scale and a powder rotary valve, a powder additive is added through a feeding port in the upper portion of the additive feeding hopper, and an exhaust port is formed in the top of the additive feeding hopper. An exhaust fan is arranged on the side of the additive feeding hopper, the exhaust fan is started during feeding so as to prevent the powder additive from flying out, and extracted gas is exhausted through the exhaust fan; the powder additive flows into the additive storage bin through a pipeline at the bottom of the additive feeding hopper by virtue of gravity; a powder additive enters a powder weightlessness scale through a pipeline at the bottom of the additive storage bin, the adding amount of the powder additive is measured through the powder weightlessness scale, and the powder additive is conveyed to a rotary valve through a discharging screw. The powder additive is added into an ultra-high molecular weight polyethylene powder air conveying system pipeline from the bottom of the rotary valve, and it is guaranteed that the powder additive and the ultra-high molecular weight polyethylene powder are fully mixed.
Owner:NORTH HUAJIN CHEM IND CO LTD

A single-shot detection of ONOO - Near-infrared ratiometric fluorescent probe and preparation method and application thereof

ActiveCN117164575BSignificant change in fluorescenceGood Ratio TrendOrganic chemistryFluorescence/phosphorescenceFluoProbesPhoto stability
The invention discloses a method for detecting peroxynitrite (ONOO) by single excitation. ‑ Near-infrared ratiometric fluorescent probe and its preparation method and application. The structural formula of the fluorescent probe is shown in Formula I below, and is named ER-MPTC (R=H) and ER-DMPTC (R=CH3). The fluorescent probe of the present invention is a reactive probe, and the fluorescent probe uses the oxidative cleavage of the carbon-carbon double bond as ONOO ‑ The fluorescent probe of the present invention showed in vitro detection of ONOO ‑ The fluorescent probe of the present invention has good ratio response, excellent selectivity and high sensitivity. At the same time, it has good photostability, is stable in a wide pH range and has an optimal response signal in the physiological pH range, which can meet the requirements of ONOO in biological tissue samples. ‑ testing requirements.
Owner:TECHNICAL INST OF PHYSICS & CHEMISTRY - CHINESE ACAD OF SCI

Functionalized silicon dioxide modified nylon anti-aging solid coating and preparation method thereof

The invention relates to the technical field of coatings, and discloses a functional silicon dioxide modified nylon anti-aging solid coating, compared with a pure-phase nylon solid coating, the nylon solid coating added with benzophenone tetramethyl piperidinyl nano silicon dioxide has better mechanical performance and anti-aging performance, and the functional silicon dioxide modified nylon anti-aging solid coating can be applied to the field of anti-aging coatings. Nano silicon dioxide is added into the coating, the mechanical performance of the coating is improved, the anti-aging capacity of the coating is also improved, the benzophenone molecular derivative has good ultraviolet absorption capacity, the anti-aging capacity of the coating is improved after the benzophenone molecular derivative is added into the coating, hindered amine molecular groups can achieve a synergistic effect by being grafted with the benzophenone derivative, and the anti-aging performance of the coating is improved. The ultraviolet absorption and aging resistance of the benzophenone derivative are improved.
Owner:WUHAN WEIQIYIN TECHNOLOGY CO LTD

Crosslinked anthraquinone-benzoquinone polymer containing arylamine bonds for cosmetic dyeing as well as preparation method and application of crosslinked anthraquinone-benzoquinone polymer

The invention discloses a crosslinked anthraquinone-benzoquinone polymer containing arylamine bonds for cosmetic dyeing as well as a preparation method and application of the crosslinked anthraquinone-benzoquinone polymer, and belongs to the technical field of cosmetics. The structural general formula of the polymer is as shown in formulas 1-3 in the specification. The preparation method comprises the following steps: (1) adding the component A and the component B into the component C, heating and stirring to obtain a mixed solution; and (2) centrifuging the obtained mixed solution, taking the supernatant, freezing the supernatant in a refrigerator, and performing vacuum freeze drying to obtain the product. The product provided by the invention can solve the problems of non-uniform dyeing process, insufficient color fastness and the like caused by poor dyeing stability, water solubility and hydrophilicity in the existing organic cosmetic dyeing agent. The chemical reaction conditions are mild, the method is simple, no side reaction occurs, and the obtained polymer can be used in the technical field of cosmetics and has wide application prospects.
Owner:JIAMUSI UNIVERSITY

Hemicyanine photosensitizer as well as preparation method and application thereof

The invention provides a hemicyanine photosensitizer as well as a preparation method and application thereof, and belongs to the field of biological medicines. A hemicyanine dye-based molecule with a D-pi-A structure is developed through donor substitution engineering, and the structure of the hemicyanine dye-based molecule is shown as a formula I in the specification. The hemicyanine dye-based molecule has excellent spectral performance. The PLH1100 nano assembly further constructed on the basis of the hemicyanine dye-based molecule has excellent brain targeting property, tumor enrichment property, light stability and biocompatibility as well as excellent photothermal conversion efficiency and NIR-II tumor imaging capability, and is suitable for photothermal immunotherapy of glioblastoma. In addition, the invention also finds that the PLH1100 can significantly enhance the curative effect of a bispecific T cell adapter (Fn14 * CD3BiTE) aiming at an Fn14 target spot, the combination of the PLH1100 and the Fn14 * CD3BiTE adapter plays a synergistic role in photothermal immunotherapy, a new way is opened up for clinical treatment of glioblastoma, and the PLH1100 and the Fn14 * CD3BiTE have significant clinical application potential. # imgabs0 #
Owner:SICHUAN UNIV

Textile dye as well as preparation method and dyeing method thereof

The invention provides a textile dye as well as a preparation method and a dyeing method thereof, the preparation method of the textile dye comprises the following specific steps: S1, carrying out superfine grinding on a natural extract until the particle size is 2-10 microns to obtain extract powder; s2, uniformly mixing the extract powder with modified glucan, metal salt grafted cellulose whiskers and polylactic acid microspheres to obtain a material; s3, adding the materials into water, stirring, curing, drying and crushing to obtain the dye. The natural extract powder, the modified glucan, the metal salt grafted cellulose whiskers and the polylactic acid microspheres are compounded, the dye is green, environmentally friendly and safe, the obtained dye is high in stability, has the effects of being high in dye uptake and uniform in dyeing and is high in affinity to textiles, and the obtained dyed textiles are good in color fastness, high in light stability, not prone to fading and good in color fastness. And the method has important popularization and application values.
Owner:HUNAN JUNBANG TEXTILE TECH CO LTD

Preparation method and application of a fluorescent probe for screening monoamine oxidase B inhibitors

This invention belongs to the field of biodetection technology, specifically relating to a method for preparing and applying a fluorescent probe for screening monoamine oxidase B inhibitors. The method for preparing the fluorescent probe described in this invention is simple, convenient, and low in synthesis cost. The fluorescent probe prepared using this method exhibits good specificity and high sensitivity. The probe has a large fluorescence emission wavelength, which can effectively avoid fluorescence interference from chemical components in traditional Chinese medicine, thereby improving detection sensitivity. It shows promising application prospects in the screening of monoamine oxidase B inhibitors from traditional Chinese medicine.
Owner:SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE