72 results about "Magnolol" patented technology

The invention provides fluorenyl magnolol light-cured solder resist ink and a preparation method thereof, the solder resist ink comprises the following raw material components by mass: 20%-60% of fluorenyl magnolol light-cured resin, 10%-25% of a reactive diluent, 10%-30% of a nano filler, 1%-5% of a photoinitiator, 0.1%-5% of an auxiliary agent, and the balance of a solvent, the fluorenyl magnolol light-cured resin is prepared by reacting 9-fluorenylidene acetic acid with thionyl chloride to generate an intermediate product fluorenyl anhydride, and then reacting the intermediate product fluorenyl anhydride with magnolol. Wherein the molar ratio of magnolol to thionyl chloride to 9-fluorenylidene acetic acid is 1: (2-4): (2-4). The preparation process is simple, toxic by-products are avoided, the prepared solder resist ink has excellent flame retardance, heat resistance and adhesive force, low dielectric constant and high hardness, the problems of high dielectric loss, insufficient flame retardance and BPA toxicity of traditional ink are solved, and the solder resist ink is completely suitable for production and manufacturing of PCB substrates for high-frequency communication.

The present invention relates to a pharmaceutical composition for preventing, ameliorating or treating diseases associated with brain cognitive function, a food composition for improving brain cognitive function, a feed composition for improving brain cognitive function, and a method for preparing same and, specifically, to: a pharmaceutical composition for preventing, ameliorating or treating diseases associated with brain cognitive function, a food composition for improving brain cognitive function, and a feed composition for improving brain cognitive function, each comprising, as active ingredients, extracts of Atractylodes lancea, Eclipta prostrata, and Magnolia officinalis, and a method for preparing same; and a pharmaceutical composition for preventing, ameliorating or treating diseases associated with brain cognitive function, a food composition for improving brain cognitive function, and a feed composition for improving brain cognitive function, each comprising, as active ingredient(s), atractylodin, wedelolactone, and / or honokiol, and a method for preparing same.

The present invention belongs to the technical field of medicine. Disclosed are a class of magnolol / honokiol derivatives, a preparation method therefor, a pharmaceutical composition thereof and the use thereof. Specifically, disclosed in the present invention are magnolol / honokiol nitrone derivatives as represented by general formulas (I) and (II). Such derivatives are prepared by means of artificial synthesis. Further provided are a pharmaceutical composition containing same, and the use thereof against inflammation, against cerebral infarction, in the treatment of amyotrophic lateral sclerosis, and against cerebral trauma.

The present application relates to a kind of composition capable of relieving fatigue-related emotional fluctuation and anxiety and its application.The composition includes: and magnolol, ergothioneine, ginsenoside and plant extract;The plant source of the plant extract includes eucommia leaf and schisandra chinensis.The above components cooperate with each other, and have significant synergistic effect in relieving tension, anxious mood and anti-depression.

The invention relates to the technical field of anti-cancer drugs, and provides a traditional Chinese medicine multi-component nano drug delivery system as well as a preparation method and application thereof. According to the invention, honokiol (HN) is entrapped by adopting lipid nanoparticles formed by a berberine (BR)-disulfide bond-caprylic capric triglyceride compound, the surface of the lipid nanoparticles is coated with a gelatin layer, and quercetin (QE) is entrapped in the gelatin layer, so that simultaneous delivery of HN, BR and QE and programmed release outside and inside cells are realized. Furthermore, the surface of the gelatin layer is modified with PEG, so that the long circulation of the drug delivery system in blood is improved; furthermore, cRGD is connected to PEG, and the synergistic lung cancer resisting effect of HN, BR and QE is greatly improved through the targeting effect of cRGD. In conclusion, the drug delivery system provided by the invention can give full play to the effect of synergistically treating lung cancer by HN, QE and BR, and has a wide application prospect.

The invention relates to the technical field of biomedical materials, in particular to a COF heterojunction nanosphere with biomimetic mineralization and antibacterial functions and a preparation method and application thereof. The preparation method comprises the following steps: mixing a magnolol solution, a 1, 3, 5-tris (4-aminophenyl) benzene solution, a polyvinylpyrrolidone solution, a 2, 5-dimethoxybenzene-1, 4-dicarboxaldehyde solution and acetic acid, so as to obtain COFDMTP-coated Honokiol nanospheres; the preparation method comprises the following steps: mixing 4, 4 '-((2, 5-diformyl-1, 4-phenylene) bis (oxy)) dibutyric acid, COFDMTP (at) Honokiol nanospheres, acetonitrile and an acetic acid solution, and reacting to obtain the COFFPBA (at) Honokiol heterojunction nanospheres. The heterojunction nanosphere provided by the invention not only can promote the mineralization of acid-etched enamel, but also can effectively inhibit the growth of oral bacteria and reduce the occurrence of decayed teeth.

The invention relates to the technical field of phenolic resin, and discloses high-temperature-resistant phenolic resin and a preparation method thereof.Polytetrahydrofuran ether glycol and diphenylmethane diisocyanate are used for synthesizing a polyurethane prepolymer, a flexible chain segment is introduced, then a phenolic hydroxyl terminated polymer containing cyano groups is prepared through a condensation reaction of magnolol and dichlorobenzonitrile, and the high-temperature-resistant phenolic resin is prepared. Introducing a heat-resistant functional group into the system, and then combining the two prepolymers under the action of a catalyst to form a phenol-based intermediate; and then carrying out polycondensation on the intermediate, phenol and formaldehyde under an acidic condition to generate the cyano-modified phenolic resin. And finally, blending with boron phenolic resin to obtain the high-temperature-resistant phenolic resin. The high-temperature-resistant phenolic resin provided by the invention has better heat resistance and the preparation method thereof.

The invention discloses a sugarcane polyphenol and magnolol compound raw material as well as a preparation method and application thereof. The compound raw material is prepared from the following components in percentage by mass: 30 to 60 percent of sugarcane polyphenol extract (polyphenol is more than or equal to 20 percent), 10 to 30 percent of pure magnolol (the purity is more than or equal to 98 percent), 5 to 15 percent of cosolvent, 2 to 8 percent of stabilizer and the balance of deionized water. The preparation method comprises the following steps: extracting and purifying the sugarcane polyphenol and magnolol, dissolving the auxiliary materials, mixing, and sterilizing to obtain the finished product. The compound raw material can be used for oral care products such as toothpaste, can synergistically inhibit streptococcus mutans, destroy bacterial plaque, prevent caries and protect gingiva, is safe and stable, and is suitable for long-term use.

The invention discloses a magnesium hydride-magnolol composite polymer microneedle system as well as a preparation method and application thereof. The magnesium hydride-magnolol composite polymer microneedle system is (PVA-PVP)-x (MgH2-Mag), the mass ratio of PVA to PVP is (1: 2)-(1: 0.25); the ratio of MgH2 to Mags is 1: 1-1: 0.05; x is 1: 20-1: 5, the magnesium hydride-magnolol composite polymer microneedle (PVA-PVP)-x (MgH2-Mag) for treating androgenic alopecia is in a three-dimensional microneedle form, the height is 120-950 [mu] m, the substrate width is 80-500 [mu] m, and the needle tip diameter is 6-80 [mu] m. Through unique structural design and material combination, efficient co-delivery and synergistic release of the two active components are realized, and a brand new solution is provided for AGA treatment.

This invention discloses a traditional Chinese medicine composition for combating mandarin fish double RNA virus, comprising at least one of geniposide, baicalin, luteolin, magnolol, and mangiferin as active ingredients. The invention also discloses a method for preparing the traditional Chinese medicine composition and its applications. This invention can significantly inhibit the proliferation and replication of mandarin fish double RNA virus and significantly improve the survival rate of mandarin fish.

The invention belongs to the technical field of organic synthesis, and discloses a dialkylated cationic derivative based on honokiol mother nucleus as well as a preparation method and antibacterial application of the dialkylated cationic derivative. The preparation method comprises the following steps: mixing honokiol, potassium carbonate, dibromoalkane and acetone, and carrying out first reaction to obtain an intermediate product; and mixing the intermediate product, a compound R1H and acetonitrile, and carrying out a second reaction to obtain the honokiol mother nucleus-based dialkylated cationic derivative. A series of novel amphiphilic derivatives are designed and synthesized by reasonably modifying a natural product honokiol, and the novel amphiphilic derivatives show effective in-vitro antibacterial activity on gram-positive bacteria.

The invention discloses a bactericide and device for improving wheat stem rot resistance in the field of agricultural biocides, and the bactericide comprises the following components in parts by weight: 10-15 parts of magnolol, 30-50 parts of carvacrol and 1 part of ethapyroxad, and the bactericide comprises the following components in parts by weight: 10-15 parts of magnolol, 30-50 parts of carvacrol and 1 part of ethapyroxad. And the bactericide comprises the following components in parts by weight: 15 parts of magnolol, 40 parts of carvacrol and 1 part of ethapyroxad, or 10 parts of magnolol, 30 parts of carvacrol and 1 part of ethapyroxad. The biological activity of the bactericide and the affinity of succinate dehydrogenase are improved by modifying ethane on amino nitrogen of pydiflumetofen, the inhibition effect and stability are improved by mixing natural plant phenol, meanwhile, environmental pollution is reduced, and the mutation speed of pathogenic bacteria is delayed.

The present application relates to a high-refractive material based on biomass magnolol and honokiol. Specifically, the high-refractive material of the present application can be obtained by photo-curing reaction of a photo-curable monomer and a plurality of mercaptans / mercaptanols under photo-initiation, wherein the photo-curable monomer is derived from a monomer containing an allyl functional group derived from biomass magnolol and honokiol. The high-refractive material provided by the present application has good optical performance, in particular, it not only has a high refractive index (1.67-1.71) but also has a relatively high Abbe number (35-24).

The application discloses a kind of carbon fiber material for unmanned aerial vehicle and preparation method thereof, belong to unmanned aerial vehicle material technical field.The carbon fiber material, by mass fraction, including following raw materials:PA612 100 parts, PA6T / 6I 30-40 parts, modified carbon fiber 10-30 parts, flame-retardant compatibilizer 6-10 parts, lubricant 1-5 parts, antioxidant 0.5-1.5 parts, wherein the modified carbon fiber is prepared by silane coupling agent grafting mercapto after surface oxidation of carbon fiber, and then combined with magnolol epoxy monomer by click reaction of mercapto and double bond;Flame-retardant compatibilizer contains phenyl phosphoramide structure and terminal aldehyde group.The carbon fiber material prepared by the application uses PA612 and PA6T / 6I as blended nylon matrix resin, synchronously adds modified carbon fiber and flame-retardant compatibilizer, and by intermolecular interaction, the material has excellent mechanical strength and reliable flame-retardant safety.

The present invention relates to a method for manufacturing at least one single-strand filament-resin composite comprising filaments embedded in a cross-linked resin, using a magnolol-based resin composition. The present invention also relates to a composite based on at least one reinforcing element and said resin composition.

The application provides a nano bactericide and a preparation method and application thereof. The Mag@ZIF-8 nano composite material synthesized based on a competitive coordination strategy and containing two coordination structures of zinc ion-2-methyl imidazole and zinc ion-magnolol simultaneously, significantly increases the inhibition of ZIF-8 on pathogenic fungi. In addition, the results of the synergistic effect experiment show that there is a synergistic effect between Mag@ZIF-8 and the bactericide fludioxonil, which provides a new idea for the synergistic effect of the bactericide in a reduced amount.

The application belongs to the technical field of content detection, and discloses a kind of HPLC detection methods for simultaneously determining the content of multiple components in semen Cannabis capsules.The detection method includes mixing reference solution, chrysophanol and methanol to obtain mixed reference solution.The reference solution includes physcion solution, magnolol solution, houpo chrysophanol solution, emodin solution, rhein solution, nobiletin solution, aloe emodin solution, hesperidin solution and paeoniflorin solution;The contents of semen Cannabis capsules are mixed with methanol, and the test solution is obtained after heating and refluxing;The mixed reference solution and test solution are respectively sucked and injected into high performance liquid chromatograph.The detection method can simultaneously determine the content of multiple index components, can comprehensively reflect the quality of the preparation, and the test method has excellent precision, repeatability, stability and high sample recovery rate.

This invention belongs to the field of pharmaceutical technology and relates to a preparation process of a modified Huoxiang Zhengqi compound. The preparation process is as follows: Pinellia ternata and Angelica dahurica are percolated; Pogostemon cablin, Perilla frutescens, Citrus reticulata peel, Magnolia officinalis, and Atractylodes macrocephala are extracted in groups for 2-5 hours, and the total volatile oil is collected. The residues of each group are decocted with water, and the decoctions of each group are collected; Poria cocos, Platycodon grandiflorus, Glycyrrhiza uralensis, Areca catechu peel, Ziziphus jujuba, and Zingiber officinale are decocted with water to obtain a decoction; the total volatile oil is added to an inclusion material, and inclusion is obtained using an ultrasonic-assisted method; the percolation and decoctions are combined, concentrated, and centrifuged to obtain a supernatant; a preservative is added to the supernatant and the inclusion material to obtain the final product. This invention extracts medicinal materials containing volatile oils in groups and uses a cyclodextrin inclusion complexation process, which not only improves the total extraction rate of volatile oils, but also increases the content of hesperidin, hydrated oxypenicillin, magnolol, honokiol, patchouli flavonol, and baicalein, while improving the taste and flavor of the flavored patchouli flavonoid compound.

The present invention relates to an anti-aging composition containing a Magnolia officinalis extract or magnolol, honokiol and 4-O-methlyhonokiol compounds. The extract or compound restores mitochondrial functions of senescent cells, reduces damaged DNA in cells, and restores senescent cells to a youthful cell state, and thus can be effectively used as a multifunctional cosmetic composition, a pharmaceutical composition, or a health functional food for inhibiting aging.

The present application relates to a magnolol rhamnoside, a preparation method and application thereof, and belongs to the technical field of glycoengineering. The magnolol rhamnoside, also known as magnolol-2-O-alpha-rhamnoside, is a novel derivative compound of natural product magnolol through glycosylation modification. In the present application, the water solubility and tumor cell growth inhibition activity of the magnolol rhamnoside are determined for the first time, and the results show that the magnolol rhamnoside has higher water solubility and tumor cell growth inhibition activity than magnolol, and has important application value for the research and development of new anti-tumor drugs. In the present application, a recombinant Escherichia coli co-expressing an rfbBDAC operon for synthesizing dTDP-Rha and a rhamnosyltransferase Ss-RhaT is constructed, and the magnolol rhamnoside is prepared by microbial fermentation conversion method. The recombinant Escherichia coli is used to efficiently synthesize the magnolol rhamnoside by fermentation method with magnolol added in the culture medium as a substrate.

The invention discloses preparation and application of a novel magnolol and jatrorrhizine conjugate, relates to the technical field of medicines, and aims to overcome the defects of poor drug resistance and insufficient activity of a single-target anti-cancer drug. According to the technical scheme, acetone or acetonitrile is used as a solvent, and through a two-step substitution reaction, the magnolol and jatrorrhizine conjugate is obtained; the preparation method comprises the following steps: reacting magnolol with dibromo-alkane to generate an intermediate B, and conjugating the intermediate B with jatrorrhizine to obtain a final product with a general formula C; or the jatrorrhizine reacts with dibromo alkane to generate an intermediate E, and then the intermediate E is conjugated with magnolol to obtain the final product of the general formula C. In the preparation process, reaction conditions (such as potassium carbonate alkaline environment and 82 DEG C reflux) are optimized, and high yield and purity are realized. The conjugate disclosed by the invention is widely applied to the anti-tumor field, has remarkable inhibitory activity on various cancer cells (such as non-small cell lung cancer cells HCC827 and human lung adenocarcinoma cells H1975), has better effects than magnolol and jateorhizine monomers, and provides a new candidate for research and development of multi-target drugs.

The present application relates to a kind of bacteriophage lytic enzyme LysSPYS2, containing bacteriophage lytic enzyme composition and its application, bacteriophage lytic enzyme LysSPYS2 sequence is as shown in SEQ ID No.1, the bacteriophage lytic enzyme has high-efficiency, broad-spectrum bactericidal effect;It has lytic effect to a variety of bacteria, can be used as bacteriostatic agent;Further, the bacteriophage lytic enzyme is combined with polymyxin B, can exert synergistic antibacterial effect, significantly reduce the amount of antibiotic;The bacteriophage lytic enzyme can also be used with Magnolol, realize outstanding bacteriostatic effect.

The present application provides a kind of composition containing sophorolipid and magnolia alcohol and its preparation method and application, specifically related to daily chemical product technical field.The composition of the present application includes the mass ratio of 1:0.5-2.5:0.8-1.2 sophorolipid, magnolia alcohol and radix bupleuri extract, wherein, radix bupleuri extract is prepared by ultrasonic-assisted low eutectic solvent extraction method, and the obtained radix bupleuri extract has synergistic effect with sophorolipid and magnolia alcohol, can improve the bacteriostatic, anti-inflammatory, moisturizing, soothing effect of composition.

This invention relates to a phage lysin LysSPYS1, a composition containing the phage lysin, and their applications. The sequence of the phage lysin LysSPYS1 is shown in SEQ ID No. 1. This phage lysin exhibits highly efficient and broad-spectrum bactericidal activity; it has a lytic effect on a variety of bacteria and can be used as a bacteriostatic agent. Furthermore, combining this phage lysin with polymyxin B can exert a synergistic antibacterial effect, significantly reducing the amount of antibiotics used. The phage lysin can also be used in combination with magnolol to achieve a prominent antibacterial effect.

The present invention relates to a cosmetic composition comprising a glutathione precursor and a lignan-based compound derived from magnolia, and provides a cosmetic composition having an excellent antioxidant effect by securing the efficiency of a complex synergistic combination of honokiol and an antioxidant amino acid.

The invention belongs to the technical field of organic synthesis, and provides a honokiol phosphine salt derivative as well as a preparation method and application thereof, and a novel magnolol derivative is designed and synthesized by integrating a cationic head group and a hydrophobic chain. The compound shows potent activity (MIC = 1-4 [mu] g / mL) on a series of gram-positive bacteria, meanwhile, the hemolytic activity is extremely low (HC50 = 106.9 [mu] g / mL), and the cytotoxicity is also low (CC50 = 19.25 [mu] g / mL). In addition, the derivative also has the capabilities of rapid sterilization, low drug resistance, good plasma stability and capability of inhibiting biofilm formation and destroying mature biofilms. And compared with vancomycin, the vancomycin-containing antibacterial peptide has the advantage that the bacterial load can be obviously reduced.

The invention belongs to the technical field of agricultural compositions, and particularly relates to an agricultural composition for preventing and treating cryphonectria parasitica. The active ingredients of the agricultural composition comprise carbendazim and magnolol, and the mass ratio of carbendazim to magnolol is 13: 3-2: 17, preferably 3: 14. The composition can be prepared into dosage forms such as wettable powder or a suspending agent and the like. An indoor toxicity test shows that the magnolol and the carbendazim have a synergistic effect on inhibiting the activity of the cryphonectria parasitica after being compounded, and a field control effect test further proves that the control effect of a pesticide group compounded by the magnolol and the carbendazim on the cryphonectria parasitica is obviously superior to that of a single dosage. The pesticide composition provided by the invention solves the technical problems that the prevention effect is reduced and the resistance of pathogenic bacteria is enhanced when a single dosage of carbendazim is applied to prevention and treatment of cryphonectria parasitica, has the characteristics of high efficiency, low residue and environmental friendliness, and has a good market application prospect.

The invention discloses a hermetia illucens sand organic fertilizer based on kitchen garbage as well as a preparation method and application thereof, and relates to the technical field of biology. The hermetia illucens insect sand organic fertilizer is prepared from the following components in parts by weight: 90 to 110 parts of hermetia illucens insect sand, 11 to 15 parts of corn straw powder, 8 to 12 parts of sawdust and 2 to 2.5 parts of bioactive substances, the bioactive substances comprise arctiin and magnolol; the mass ratio of arctiin to magnolol is (1-9): 9. According to the organic fertilizer and the preparation method thereof, the double breakthrough of efficient recycling of the kitchen garbage and high-value utilization of the organic fertilizer is achieved, the organic fertilizer provided by the invention can remarkably promote plant growth and prevent and treat clubroot of plants, the problems of chemical pesticide residues and drug resistance of pathogenic bacteria can be avoided, and an effective solution is provided for recycling of the kitchen garbage and development of green agriculture.

The invention relates to the technical field of cosmetics, and particularly discloses a composition with soothing, anti-allergy and itching relieving effects and a preparation method thereof. According to the composition, grease, a humectant, an emulsifier and a preservative are used for constructing a basic system, and composite microgel is introduced as a core carrier. According to the composite microgel, calcium alginate gel containing magnolol nano oil drops and a paeonol clathrate compound serves as an inner core, a shell is formed by compounding sodium alginate and chitosan on an outer layer so as to wrap cardiospermum halicacabum extract lipidosome, and synergistic delivery and long-acting slow release of three active ingredients are achieved through the structure; the stability, the skin permeability and the efficacy synergy of the composition are obviously improved. The preparation technology is controllable, skin irritation can be effectively relieved, anaphylactic reaction is relieved, pruritus is relieved, and the composition is suitable for sensitive skin care.

The invention relates to the technical field of polyester degradable plastics, and discloses a bio-based renewable plastic, a preparation method and an application of the bio-based renewable plastic in toys. The preparation method of the bio-based renewable plastic comprises the following steps: grafting modified magnolol onto a composite modified halloysite nanotube to obtain a multifunctional modified halloysite nanotube; modifying the multifunctional modified halloysite nanotube with ureido pyrimidone to obtain an organic modified halloysite nanotube; reacting the intermediate product, citric acid and 1, 6-hexanediol to obtain citric acid-based polyester; mixing citric acid-based polyester, a silane coupling agent KH550, the organic modified halloysite nanotube, palm wax and an antioxidant, extruding, and granulating, so as to obtain the bio-based renewable plastic. The bio-based renewable plastic provided by the invention is renewable and degradable, has excellent mechanical properties, antibacterial properties, heat resistance and ultraviolet resistance, can be used in common toys, and can also meet the use requirements of toys for children.