160results about How to "Precision release" patented technology

The invention relates to the technical field of biological pharmacy, and discloses a probiotic microcapsule with a function of improving intestinal microecology, which comprises the following components in percentage by weight: lactobacillus rhamnosus: each gram of formula contains 1010 CFU of lactobacillus rhamnosus; lactobacillus acidophilus: each gram of the formula contains 109 CFU; clostridium butyricum: each gram of the formula contains 108 CFU; 5%-8% of a nano sodium alginate-chitosan compound; 3%-5% of peptide nanoparticles; 2%-4% of a natural polymer intelligent response film; 3%-6% of arabinoxylan oligosaccharide; 4%-7% of resistant dextran; 2%-4% of lentinan; and 0.1%-0.3% of resveratrol. Through a double-layer or three-layer embedding technology of the nano sodium alginate-chitosan compound and the intelligent response polymer film, the tolerance of the probiotics in gastric acid and cholate environments is remarkably enhanced, and targeted release of the probiotics in small intestines and colon is ensured.

The invention relates to the technical field of agricultural automation, in particular to a multi-layer three-dimensional cultivation automatic transplanting robot for a plant factory, the multi-layer three-dimensional cultivation automatic transplanting robot comprises a cultivation frame, a seedling raising plate is arranged on the side face of the cultivation frame, and the robot comprises a control module, a visual module, a positioning module, a moving module and a clamping module. Comprising a clamping unit and a clamping seat, the clamping seat is fixedly connected with a moving seat, a plurality of lifting units are arranged below the clamping seat, the clamping unit comprises a clamping block detachably connected with the lifting units, a clamping motor is arranged in the clamping block, a plurality of clamping grooves are formed in the lower end face of the clamping block, and clamping jaws are movably arranged in the clamping grooves. A crank is further arranged in the clamping block, the two ends of the crank are connected with the output end of the clamping motor and the clamping jaw respectively, opening and closing actions of the clamping jaw are achieved, by means of the design, the robot can accurately clamp and release the field planting basket, and the transplanting accuracy and consistency are improved.

The invention relates to the technical field of welding, in particular to a lead-free solder composition and a preparation method thereof. The composition comprises brazing filler metal and a brazing flux, wherein the brazing filler metal comprises 55 to 65 parts of copper, 30 to 40 parts of zinc, 0.5 to 1 part of silver, 0.1 to 1 part of tin, 0.1 to 0.5 part of nickel, 0.02 to 0.15 part of lanthanum, 0.03 to 0.15 part of cerium and 0.05 to 0.2 part of indium; the brazing flux comprises 18-22 parts of borax, 13-17 parts of boric acid, 25-32 parts of a potassium fluoride and potassium fluoborate compound, 3-5 parts of calcium fluoride, 12-16 parts of aluminum oxide and 8-11 parts of magnesium oxide. The lead-free solder composition does not contain toxic lead elements, pollution to the environment and the ecological system is little, the wettability, corrosion resistance, strength, stability and the like of the lead-free solder composition are improved, and the welding quality is comprehensively improved. According to the preparation method, uniform distribution and accurate control of the brazing filler metal and the brazing flux are guaranteed, stability and consistency of product quality are guaranteed, and the preparation method is easy and convenient to operate and suitable for mass production.

The invention discloses a cationic polymer-based proteolysis targeting chimera as well as preparation and application thereof, and belongs to the fields of targeting protein degradation and nanotechnology. According to the chimera, a cationic polymer is used as a connecting arm to connect a target protein ligand and an E3 ubiquitin ligase ligand to form a ternary complex, so that efficient degradation of target protein is realized. By adjusting the ligand proportion, chimeras with different degradation efficiencies can be synthesized, and accurate regulation and control are realized. The pH-responsive nano-drug obtained by hydrolyzing the targeting chimera by using the targeting protein can respond to an acidic tumor microenvironment, specifically release the chimera, and improve the targeting property and the treatment effect of the drug. Compared with the traditional PROTACs, the compound has higher bioavailability and tumor permeation effect; the preparation method of the nano-drug is simple and easy to implement, provides possibility for preparation of high-performance nano-drugs, shows potential in preparation of anti-tumor cell drugs, provides new thoughts and methods for tumor treatment, and has important clinical application value.

The invention discloses methotrexate-loaded sulfonated bacterial cellulose / chitosan hydrogel for treating psoriasis and a preparation method of the methotrexate-loaded sulfonated bacterial cellulose / chitosan hydrogel. The method comprises the following steps: firstly, loading methotrexate by using sulfonated bacterial cellulose, and then coupling with chitosan to form the methotrexate-loaded sulfonated bacterial cellulose / chitosan hydrogel. The synthesis method is simple, the prepared methotrexate-loaded sulfonated bacterial cellulose / chitosan hydrogel can promote the transdermal release effect of methotrexate and control the release speed of methotrexate, skin inflammation caused by psoriasis is continuously and effectively relieved, and the methotrexate-loaded sulfonated bacterial cellulose / chitosan hydrogel has good biological safety.

The invention discloses a compound feed additive as well as preparation and application thereof, and belongs to the technical field of feeds. The additive comprises a first composition and a second composition, the first composition comprises microcapsules formed by coating short-chain fatty acid and / or short-chain fatty acid derivatives with triglyceride carrying beta-glucuronide residues, and the second composition comprises microcapsules formed by coating short-chain fatty acid and / or short-chain fatty acid derivatives with triglyceride carrying beta-glucuronide residues. The second composition comprises medium-chain fatty acid and / or medium-chain fatty acid derivatives, and microcapsules formed by coating short-chain fatty acid and / or short-chain fatty acid derivatives with long-chain fatty acid and / or long-chain fatty acid derivatives. The invention effectively solves the problem that short-chain fatty acids and derivatives thereof are decomposed in advance before reaching target sites of intestinal tracts, so that the short-chain fatty acids and derivatives thereof can be transported to the whole course of digestive tracts, realize precise metabolism of parts in colon positions, and are suitable for balance of long-chain, medium-chain and short-chain fatty acids in intestines and stomachs of piglets. The feed can achieve the positive effects of promoting growth, improving the digestibility of nutrient substances, improving intestinal health and the like, and has a good application prospect in animal breeding.

The invention provides a preparation method and application of a double-response type controlled-release pesticide. The method comprises the following steps: S1, preparing modified biochar; s2, preparing a drug carrier by using the modified biochar; and S3, preparing the double-response controlled-release pesticide by using the drug carrier. The problems that an existing controlled-release pesticide cannot meet the controlled-release function easily, the preparation process is complex, and large-scale preparation is difficult are solved.

The invention discloses a microneedle patch loaded with a sorafenib and copper-doped Prussian blue nano material and application of the microneedle patch in in-situ triple-negative breast cancer treatment. The sorafenib and the copper-doped Prussian blue nano material are loaded in a needle body of the microneedle patch. The microneedle patch can accurately deliver nanoparticles and sorafenib to tumor tissues, the chemical kinetics effect is enhanced through an efficient and mild photothermal therapy, the ferroptosis of triple negative breast cancer cells is enhanced through ferroptosis induced by the nanoparticles and sorafenib in cooperation with drugs, then cell death is induced, and the curative effect is improved. And a brand-new and promising treatment method is provided for in-situ triple-negative breast cancer treatment.

The invention relates to a compound preparation for improving the physique of weak stiff livestock. Every 100 ml of the compound preparation mainly comprises the following components according to a ratio: 0.1 to 0.3 g of vitamin E, 1 to 3 g of lactobacillus, 1 to 2 g of bile acid, 1 to 3 g of xylanase, 0.2 to 0.4 g of vitamin B1, 0.2 to 0.4 g of vitamin B2, 0.2 to 0.4 g of vitamin B6, 0.2 to 0.4 g of vitamin B12, 1 to 3 g of nicotinamide, 0.5 to 1.0 g of butafosfan, 1 to 3 g of taurine, 1 to 3 g of lysine, 0.5 to 1.0 g of levamisole hydrochloride, 5 g of soybean oil, 50 g of gelatin liquid, 5 to 10 ml of sodium sulfate solution, 1 to 2 g of Pickering emulsifier, 3 to 5 g of liquid paraffin and 1 to 2 g of Tween-80. The compound preparation not only pays attention to nutritional supplement, but also pays attention to regulation of an immune system and improvement of intestinal flora balance, so that the physique of the weak stiff livestock is comprehensively improved, and powerful support is provided for efficient development of the breeding industry.

The invention discloses a lamination equipment diaphragm tension control method and a laminated battery, the lamination equipment comprises a diaphragm unwinding mechanism, a diaphragm tension mechanism, a diaphragm buffer mechanism, a fixed roller, a diaphragm roller mechanism and a lamination table, and a diaphragm sequentially passes through the diaphragm tension mechanism, the diaphragm buffer mechanism, the fixed roller, the diaphragm roller mechanism and the lamination table. The control method comprises the steps that the starting position, the first middle position and the final position of the diaphragm double-roller mechanism in the movement process are determined; the first middle position is located between the initial position and the final position, and when the diaphragm double-roller mechanism is located at the first middle position, the length of the diaphragm from the fixed roller to the initial position of the lamination table is the shortest length. And in the process that the diaphragm double-roller mechanism moves from the initial position to the first middle position, the maximum damping tension of the diaphragm tension mechanism is controlled to be first tension. And in the process that the diaphragm double-roller mechanism moves from the first middle position to the final position, the maximum damping tension of the diaphragm tension mechanism is controlled to be second tension, and the first tension is larger than the second tension.

The invention belongs to the field of water environment restoration materials, and discloses a preparation method of a slow-release / temperature-controlled ferrate-silicon dioxide core-shell material and an antibiotic removal effect of the slow-release / temperature-controlled ferrate-silicon dioxide core-shell material. The method mainly comprises the following steps: preparing a slow-release ferrate-silicon dioxide core-shell material by adopting an in-situ growth coating synthesis method and combining potassium ferrate with strong oxidizing property on the basis of a silicon dioxide material which is excellent in biocompatibility, relatively large in specific surface area and pore volume and easy in surface modification; furthermore, by loading a phase change material on the slow-release ferrate iron-silicon dioxide core-shell material, a slow-release and temperature-controlled composite material is prepared, and efficient utilization and accurate release of an oxidation active substance are realized. According to the invention, slow-release efficient utilization and temperature-controlled accurate release of oxidation active substances are realized, and the oxidation utilization efficiency and removal capacity of the oxidizing agent on target pollutants are improved.

The invention relates to the field of evaporation equipment, in particular to a spinning uniform evaporation system, which comprises a cabin body, a substrate frame and a substrate table, and further comprises a revolution and rotation module, an evaporation module and a control module, which are arranged in the cabin body, and the revolution and rotation module comprises a revolution driving mechanism and a rotation driving mechanism which are used for driving the substrate frame; the evaporation material regulation and control module comprises a heating module, an evaporation conduction cavity, a gas concentration detector and an electromagnetic valve and is used for regulating and controlling the diffusion time of the evaporation material; the height adjusting module comprises a main hydraulic lifting rod and an auxiliary hydraulic lifting rod and is used for achieving height adjustment of the substrate frame relative to the evaporation source. The substrate frame rotates while revolving, so that an evaporation material is more uniformly distributed on the surface of the substrate; and the design of the evaporation conduction cavity of the slender cavity is combined with the gas release structure controlled by the electromagnetic valve, so that the evaporation material can be uniformly distributed and deposited on the substrate at a stable rate, and the consistency of the overall film thickness is improved.

The invention discloses a microneedle patch loaded with vancomycin and a gold / zinc cerium composite nanomaterial and application of the microneedle patch in abscess wound treatment, the microneedle patch comprises a backing layer and a needle body array arranged on the backing layer, the backing layer and the needle body array are formed by an aqueous solution of a degradable polymer, vancomycin and a gold / zinc cerium composite nano material are loaded in an aqueous solution of the degradable polymer for forming the needle body array. According to the microneedle patch disclosed by the invention, based on the photo-thermal synergistic effect of the antibiotics and the gold / zinc-cerium composite nanomaterial, rapid healing of abscess wounds is realized from the aspects of inhibiting growth of bacteria, relieving oxidative stress, promoting angiogenesis and the like.

The invention provides traditional Chinese medicine fermented disaccharide encapsulated nano anti-dandruff, hair-growing and oil-controlling shampoo and a preparation method, and relates to the field of daily chemical products, and the shampoo comprises the following components: a compound fermentation product, lactobacillus crispatus, lactobacillus plantarum, a disaccharide activity protection system, a basic component and a nano oil-controlling component; the compound leavening is prepared from cacumen biotae, radix polygoni multiflori, radix ginseng, fructus cnidii and orchid; the disaccharide activity protection system comprises maltotetraose and trehalose; the disaccharide activity protection system wraps a fermented material formed by fermenting the compound fermentation product, the lactobacillus crispatus and the lactobacillus plantarum to form a disaccharide glassy state layer; the nano oil control component is prepared from calamine powder and chitosan-sodium alginate; the basic component is prepared from tea bran, radix sophorae flavescentis, herba ecliptae, radix notoginseng, fructus ligustri lucidi, tea saponin microcapsules and tremella polysaccharide. According to the invention, through fermentation conversion of the orchid, disaccharide glassy state protection and slow release of the nano calamine, activity enhancement, stable retention and accurate release are realized, and the effects of removing dandruff, relieving itching, controlling oil and growing hair are achieved.

The invention relates to the technical field of semiconductor manufacturing, and particularly discloses a wafer carrying device which comprises a carrying track, a device base is arranged on the carrying track, a round base is installed on the lower side of the device base, a pneumatic suction cup is installed below the round base, and a plurality of clamping blocks are arranged on the peripheral side of the round base. The lower side of the clamping block is rotatably connected with left and right strip clamping blocks, and the lower sides of the outer ends of the strip clamping blocks are provided with rubber contacts. According to the wafer carrying device, the pneumatic suction cups are adopted, stability and flexibility are enhanced, a pneumatic system rapidly adjusts the adsorption force, wafer damage is avoided through the design of rubber contacts, a triangular frame ensures stable placement and reduces the falling risk, clamping block springs provide clamping force and have the buffering function, and the rubber contacts at the outer ends of clamping strip blocks ensure safe contact; the outer gear ring and the straight gear achieve synchronous movement, the clamping precision is enhanced, the overall coordination is improved through the design of the sliding sleeve base and the connecting rod, it is ensured that the device stably moves, the device adapts to wafers of different sizes, and the protection function is improved.

The invention relates to the technical field of medicine, in particular to a preparation method and application of a photodynamic-chemotherapy nano platform targeting tumor endogenous YAP1. The nano platform is hollow mesoporous silica nanoparticles (M (at) O-VNPs) loaded with oxaliplatin and VP of a macrophage membrane coating. The preparation method comprises the following steps: S1, synthesizing hollow mesoporous silica nanoparticles; s2, preparing the organic silicon nanoparticles loaded with the Verteporfin, and preparing the organic silicon nanoparticles loaded with the Verteporfin; s3, loading of the oxaliplatin; and S4, extraction and coating of a macrophage membrane. According to the invention, the macrophage membrane wrapped on the surface of the nano platform is utilized to provide good tumor targeting for the M (at) O-VNPs, and by camouflaging the macrophage membrane and the M (at) O-VNPs, not only are recognition and removal of an organism immune system successfully avoided, but also Verteporfin (VP) and oxaliplatin (OXA) can be delivered to a tumor site in a targeting manner, so that the tumor targeting of the drug is remarkably enhanced, and the drug has a good application prospect. The non-specific distribution in healthy tissues is reduced, and the systemic toxicity is reduced.

The invention provides core-shell structure nanoparticles with a mediated microenvironment for rheumatoid arthritis treatment and a preparation method thereof.The preparation method comprises the steps that a calcium peroxide precursor is dissolved in absolute ethyl alcohol containing a surfactant, and calcium peroxide nanoparticles are obtained by adding an ammonia water solution and a hydrogen peroxide solution; the preparation method comprises the following steps: carrying out surface treatment on calcium peroxide nanoparticles by using tannic acid to form a tannic acid molecular layer on the surfaces of the calcium peroxide nanoparticles so as to obtain tannic acid modified calcium peroxide nanoparticles; and forming a metal phenolic network shell on the surface of the tannic acid modified calcium peroxide nano-particle by using cerium acetate to obtain the core-shell structure nano-particle.

The invention relates to a double-response EGFR (epidermal growth factor receptor) targeted paclitaxel liposome based on heat shock protein, which adopts a pH sensitive design and is doped with heat shock protein 90 (HSP90) responsive molecule gambogic acid (GA), the surface of the liposome is modified with an EGFR antibody, and the core of the liposome is packaged with paclitaxel (PTX). According to the double-response EGFR targeted paclitaxel liposome of the heat shock protein, triple negative breast cancer cells are accurately locked through a double targeting strategy, and cell surface specific recognition is achieved through an EGFR antibody; gambogic acid GA responds to HSP90 overexpression in cells to promote drug release; the pH sensitive characteristic ensures that the medicine is quickly released in an acidic tumor microenvironment, the treatment effect is enhanced, and normal cell damage is reduced. According to the invention, the specific quick response release of the medicine is realized, the treatment accuracy and safety are improved, and the preparation method has a remarkable application prospect in the aspect of preparing the medicine for treating the triple-negative breast cancer.

The invention relates to a multifunctional manganese-based hybrid nano-platform based on NK cell membrane modification and a preparation method and application thereof, by selecting a highly branched dendritic polymer PSeSeS modified by a diselenide bond as a carrier and partially modifying mPEG and phenylboronic acid, water solubility and stability are improved, and the material is endowed with specific reactivity in a tumor microenvironment. Furthermore, potassium permanganate is reduced by using the tail end of PSeS and a tertiary amine group to generate MnO nano-particles, so that the low-oxygen environment of tumors is relieved, the photothermal therapy is enhanced, and meanwhile, active oxygen can be generated. Then doxorubicin and cGAMP are loaded, chemotherapy and immunotherapy are combined, and the tumor recognition and removal capacity of an immune system is improved; nK cell membrane modification is further adopted, so that the targeting property and the in-vivo stability are improved. The nano platform overcomes the defects of poor tumor microenvironment responsiveness, weak targeting, inaccurate drug release, single treatment mode and the like in the prior art, and can significantly improve the effect and safety of liver cancer treatment.

The invention belongs to the technical field of drug carriers, and particularly discloses a preparation method and application of a closed-loop feedback-regulation nano drug delivery system.The preparation method comprises the following steps that a starting material containing a reversible molecular library is provided, and the reversible molecular library is prepared in a buffer salt system; under thermodynamic control, adding anti-cancer drug molecules and guest molecules into the starting material; through a reversible covalent reaction process, molecules in an initial material spontaneously form a self-assembled nano-carrier containing drug molecules under the combined action of the drug molecules and guest molecules. According to the preparation method and application of the closed-loop feedback-regulation nano drug delivery system, reversible covalent reaction, closed-loop feedback-regulation and self-assembly technologies are combined, spontaneous construction of a nano carrier is achieved, and the nano carrier is endowed with excellent drug loading capacity, stability and environmental responsiveness.

The invention discloses a nanocapsule for targeting glioma containing a Cas9 / sgGDF15 compound as well as a preparation method and application of the nanocapsule, and belongs to the technical field of biological medicines. According to the nanocapsule disclosed by the invention, the glioma targeting peptide Ang with strong brain penetrating power is cross-linked on the surface, so that the glioma targeting property of the nanocapsule is improved; a disulfide bond is added on the surface of the nanocapsule, so that the nanocapsule can be prevented from being degraded by enzyme action in blood, and a Cas9 / sgGDF15 compound entrapped in the nanocapsule can be ruptured and accurately released in a high glutathione microenvironment at a tumor part of the nanocapsule, so that the GDF15 gene of glioma cells is efficiently edited, and the GDF15 gene in the glioma cells is specifically knocked out; the immunosuppressive microenvironment of the glioma is reversed, the anti-tumor effect of immune cells is recovered, and the aim of treating the glioma is achieved.

The invention discloses a probiotic / mucoprotein loaded oral microsphere system as well as a preparation method and application thereof, and belongs to the field of compositions. The preparation method of the system comprises the following steps: dissolving probiotics, Mucin and HAMA in double distilled water containing phenyl lithium phosphate LAP and calcium chloride to prepare a gel matrix solution; adding the dissolved gel matrix liquid into an oil phase solvent, and stirring at a high speed in a container; after uniformly stirring, carrying out an ultraviolet light crosslinking reaction, and after the reaction is finished, fully cleaning the obtained microspheres to remove the redundant oil phase solution, so as to obtain microspheres; and dispersing the obtained microspheres in a sodium alginate solution under an acidic condition, uniformly mixing, carrying out a cross-linking reaction, and filtering and cleaning after the reaction is finished, so as to obtain the probiotic / mucoprotein loaded oral microspheres. According to the invention, HAMA and SA are utilized to prepare an oral microsphere system resistant to gastric acid to co-deliver Mucin and EcN, so as to realize continuous and effective regulation and control of unbalanced intestinal flora by probiotics.

A mechanical high-strain guide hammering system comprises a vertical guide frame and a heavy hammer, the vertical guide frame is of a rectangular frame structure with an opening in the lower end, a hydraulic winch is fixedly mounted at the upper end of the vertical guide frame, a lifting seat is slidably mounted in the vertical guide frame, and the hydraulic winch is connected with the lifting seat through a steel cable; the lower surface of the lifting seat is connected with a hydraulic unhooking hook; a lifting point is arranged on the upper surface of the heavy hammer, the heavy hammer is connected with the hydraulic unhooking hook through the lifting point, the hydraulic unhooking hook achieves releasing and locking of the heavy hammer through a control oil way, and the heavy hammer moves up and down along an inner cavity of the vertical guide frame. A hinge seat is arranged on the side face of the vertical guide frame body, and the vertical guide frame body is connected with a mechanical arm of the excavator through the hinge seat. According to the utility model, the defects in the prior art are overcome, the accurate positioning of the heavy hammer in the hammering process can be effectively ensured, the heavy hammer is suitable for different detection environments, the risk of manual intervention is greatly reduced, and the working efficiency and the safety are improved.

The utility model discloses a full -automatic embedded part injection molding takes out piece packaging machine belongs to injection molding machine technical field, it includes work table, work table top fixed mounting has fixed mould, the fixed mould is buckled and is connected with embedded part main part, the sliding block with the guide rail sliding connection, the sliding block is located between the guide rail with the embedded part main part, the guide rail is the inclined structure, the utility model discloses through the heat absorption block absorption external heat like the heat source of mould processing, the heat transfer to first air cylinder, and the heated expansion gas (like nitrogen) in first air cylinder and second air cylinder expands in volume because temperature rises, and pressure increases, and the telescopic link of movable block outside pushes the sliding block and slides on the inclined guide rail, because the guide rail is the inclined structure, the sliding of sliding block will produce the component force along the guide rail direction, and then will embedded part main part extrude to the inboard of fixed mould, avoids in the injection molding process and causes the displacement of embedded part to influence injection molding effect.

The application provides a pentaethylenehexamine-beta-cyclodextrin grafted folic acid inclusion cannabidiol nanosphere, a preparation method and an application, the method first prepares a pentaethylenehexamine-beta-cyclodextrin grafted folic acid (PEHA-beta-CD-FA) targeting carrier, then cannabidiol (CBD) is mixed with the carrier in an ethanol-water mixed solvent in a certain proportion, a stable inclusion system is formed through ultrasonic-assisted inclusion + room-temperature light-avoiding stirring, and the system is purified through dialysis, freeze-drying or spray-drying, so that the spherical nanoparticles with uniform particle size of about 100 nm are obtained. The application solves the problems that CBD has extremely low water solubility, poor bioavailability and lacks targeted delivery, the obtained nanospheres have folic acid receptor active targeting, pH response drug release, high encapsulation rate and high colloidal stability, can significantly improve the solubility, dissolution rate and in-vivo targeted delivery efficiency of CBD, and are suitable for the fields of anti-inflammatory, neuroprotective and the like drugs, cosmetics and functional foods.

The invention provides a liquid viscosity measuring device and method.The device comprises a measuring container used for containing liquid to be measured, the top face of the measuring container is in a cone shape extending outwards, a closed control cavity is formed in the top end of the measuring container, and the inner diameter of the control cavity is smaller than the diameter of a measuring steel ball; the measuring steel ball is arranged in the measuring container; the rotating mechanism is used for driving the measuring container to rotate by 180 degrees around the horizontal axis of the measuring container, so that the measuring container is switched between an upright state and an inverted state; one end of the control cavity is directly communicated with the interior of the measuring container, the other end of the control cavity is communicated with the interior of the measuring container through a first pipeline provided with a first stop valve, and the other end of the control cavity is further provided with a pressure relief device used for adjusting the internal pressure of the control cavity. According to the invention, the ball falling time can be accurately measured, so that the liquid viscosity measurement precision is improved.

The invention relates to a rear release structure, a support and a support system, the rear release structure comprises a supporting component and a limiting unit, the supporting component is used for sleeving the support, the limiting unit is arranged on the supporting component, and the limiting unit is used for limiting a partial area of the support on the supporting component. According to the rear release structure, the support and the support system, by means of the rear release structure composed of the supporting component and the limiting unit, the support can be limited to the supporting component through the limiting unit and can also be controllably fixed to the supporting component, and the controllability means that the support can be stably limited to the supporting component and does not move unexpectedly; and when the limitation needs to be removed, the stent can be removed from the limitation relative to the supporting part at any time and separated from the supporting part, so that in the implanting process of the stent, the controllable limitation of the post-release structure on the stent can prevent the stent from generating unexpected displacement, and then when the stent is finally released, the limitation on the stent is removed according to time; and the stent is accurately released.

The present disclosure relates to a skill control method and device, electronic equipment and computer program product, and belongs to the technical field of games. The method comprises: when a game character is in a skill release state of a target skill, in response to a targeting instruction, controlling to adjust the release direction of the target skill; determining a target game object from the game scene according to the release direction; and controlling to display the internal structure of the target game object in perspective and / or the game scene blocked by the target game object in perspective. The present disclosure can assist users in accurately releasing a line-of-sight-out skill when facing a complex scene space by displaying the three-dimensional perspective structure of the target game object, thereby improving the operation efficiency of the user.

This invention discloses a ROS-responsive Trichoderma-derived composite nanoparticle in the field of plant biocontrol, its preparation method, and its application in controlling tomato gray mold. The aqueous solution of the nanoparticles contains: mesoporous silica (MSN), 6-pentyl-2H-pyran-2-one (6PP), and the plant-responsive protein Epl1. The aqueous solution of the nanoparticles uses the main metabolites of Trichoderma, 6PP and Epl1, as its core. Both 6PP and Epl1 have dual functions of broad-spectrum fungicidal activity and inducing plant immunity. MSN is synthesized using the Stöber method and modified with an S-containing backbone and surface amino groups, providing protection, slow release, and precise delivery of 6PP and Epl1. The 6PP in the aqueous solution of the nanoparticles can be rapidly released in response to low pH and high ROS conditions. The carrier works synergistically with the two components, significantly improving the induction of resistance and direct fungicidal effects on tomato plants and fruits compared to single-component methods. It is particularly suitable for foliar fungal diseases of vegetable crops in the field and has high practical value for widespread field application.

This invention belongs to the field of fire extinguishing materials and their preparation technology, and provides a fire extinguishing microcapsule and its microfluidic controllable preparation method. The preparation method is characterized by the following steps: (1) preparing fluids of each phase, (2) preparing a dual emulsion using a microfluidic device, (3) collecting and sealing the dual emulsion in a collection container, controlling the axis of the collection container to be horizontal, and controlling the collection container to rotate around its axis for 1 to 15 minutes, applying light to solidify the outer shell of the dual emulsion droplets while maintaining the rotation of the collection container, cleaning, and drying to obtain the final product. The fire extinguishing microcapsule prepared by this method consists of an outer shell and a liquid fluorine-containing fire extinguishing agent encapsulated within the outer shell. The outer shell of the fire extinguishing microcapsule has a uniform thickness, and the eccentricity between the outer shell and the core is less than 0.1. The method of this invention can achieve precise customization of fire extinguishing microcapsules according to the differentiated fire characteristics of different application scenarios, and can improve the concentricity between the core and the outer shell of existing fire extinguishing microcapsules.