The invention relates to a heart valve implantation device provided with an anchoring device. The device comprises a heart valve prosthesis, at least two sets of anchoring pins and an anchoring pin releasing device, wherein an anti-disengagement end is arranged at the near end of each anchoring pin, the anchoring pin releasing device is detachably connected with the heart valve prosthesis and comprises a delivery pipe and a push rod, the far end of the anchoring pin releasing device is in a preset shape to enable the far end of the delivery pipe to be bent integrally or partially, the part, capable of being bent, of the delivery pipe is the bent section, a rigid section is arranged at the farthest end of the delivery pipe, the distance between the farthest end of the delivery pipe and the nearest end of the bent section of the delivery pipe is larger than or equal to one sixth of the perimeter of a circle formed by means of the minimum radius of the autologous valve tissue ring of a patient, the anchoring pins are pre-arranged in the far end of the delivery pipe and located at the far end of the push rod, and the anchoring pins can be made to move towards the far end of the delivery pipe by pushing the push rod to enable the heart valve prosthesis to be fixed between the autologous tissue and the anti-disengagement end. By the adoption of the device, accurate positioning and firm anchoring can be realized.