57 results about "Heart valve replacement" patented technology

The invention relates to an artificial heart valve and a transcatheter heart valve replacement system.The artificial heart valve comprises a valve support and an outer skirt part, the valve support is provided with an inflow end and an outflow end, and the valve support is sequentially provided with a plurality of grid sets arranged in the circumferential direction from the outflow end to the inflow end; wherein the grid group closest to the inflow end is suitable for being matched with the position below the annulus plane, and the size of a net opening of at least one non-end grid group matched with the annulus plane is larger than that of a net opening of at least one axially adjacent grid group; the outer skirt part covers the outer surface of the valve stent, the outer skirt part at least covers the two adjacent grid groups close to the inflow end, and the position, close to the inflow end, of the outer skirt part is configured to be of a structure with the thickness gradually increased in the direction from the outflow end to the inflow end.

The application provides a heart valve positioning device, which comprises a first curved structure, a second curved structure, and a third curved structure. The first curved structure forms a spiral curved structure with a first size in a released state. The second curved structure forms a spiral curved structure with a second size in a released state, and the second size is greater than the first size. The second curved structure has a hollow first cavity for the first curved structure to pass through, forming the third curved structure. The distal end of the third curved structure is a free end, and the proximal end is connected with a delivery system. The third curved structure forms a spiral curved structure with a third size in a released state, and the first size is less than the third size and less than or equal to the second size. The embodiment of the application can reduce left ventricular outflow tract obstruction caused by large-scale movement of the anterior leaflet.

The invention relates to an anchor hook and methods of using the same for subannular anchoring of a transcatheter heart valve replacement, and in particular for an orthogonally delivered (side-delivered) transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the mitral or tricuspid valve from the inferior vena cava or superior vena cava, or trans-septally to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring a delivery catheter to bend 90 degrees during deployment.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

The invention relates to constriction devices and methods for deploying a laterally delivered prosthetic heart valve in a native annulus. The present invention relates to anchoring channels and subannulus anchors for transcatheter heart valve replacement (A61F2 / 2412), and in particular for transcatheter prosthetic heart valves with orthogonal delivery of an annulus support frame having a compressible wire unit, the compressible wire unit facilitates rolling and folding of the valve in a longitudinal direction or orthogonal to a central axis of the flow control member, allowing delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve, or trans-atrial delivery and deployment to the mitral valve, or delivery and deployment of a very large diameter valve from the inferior vena cava or superior vena cava to the tricuspid valve. The valve has a height of about 5 mm to 60 mm and a diameter of about 25 mm to 80 mm without the need for an over-diameter catheter and without the need for delivery and deployment from the catheter at an acute access angle.

A heart valve replacement device comprises a stent having a first end, a second end, an outer surface, and an inner surface, the inner surface defining a lumen; and a valve disposed within the lumen of the stent, the valve formed from a single sheet of tissue, the valve having an outer surface, an inner surface, and a thickness between the outer surface and the inner surface, the valve comprising at least three leaflets, wherein, the valve is attached to the stent with minimal sutures. The leaflets are formed with a curvilinear surface.

The invention relates to anchor channels and subannular anchors for a transcatheter heart valve replacement, and in particular for an orthogonally delivered transcatheter prosthetic heart valve having a annular support frame having compressible wire cells that facilitate rolling and folding the valve length-wise, or orthogonally to the central axis of the flow control component, allowing a very large diameter valve to be delivered and deployed to the tricuspid valve from the inferior vena cava or superior vena cava, or trans-atrially to the mitral valve, the valve having a height of about 5-60 mm and a diameter of about 25-80 mm, without requiring an oversized diameter catheter and without requiring delivery and deployment from a catheter at an acute angle of approach.

The present invention relates to an anchoring channel and a subannular anchor for transcatheter heart valve replacement (A61F2 / 2412), and in particular for an orthogonally delivered transcatheter prosthetic heart valve having an annular support frame having a compressible wire unit that facilitates rolling and folding of the valve longitudinally or orthogonally to the central axis of the flow control component, thereby allowing very large diameter valves to be delivered and deployed from the inferior vena cava or superior vena cava to the tricuspid valve, or delivered and deployed transatrially to the mitral valve, the valve having a height of approximately 5 mm-60 mm and a diameter of approximately 25 mm-80 mm, without the need for an overly large diameter catheter and without the need for delivery and deployment from the catheter at an acute approach angle.

Heart valve prosthesis delivery devices and methods. The devices include a delivery catheter and stabilization catheter. The stabilization catheter has expandable anchoring segments to anchor the device at a cardiac site superior to the implantation site of the heart valve prosthesis. The stabilization catheter also has a tubular assembly that includes an outer tubular member and an inner tubular member translationally displaceable within the outer tubular member. The outer tubular member defines a longitudinally extending slit and the inner tubular member defines an aperture positionable within the longitudinally extending slot. The device includes a snare and the location of the distal end of the snare adjacent to the distal portion of the delivery catheter is adjustable via translational displacement of the inner tubular member relative to the outer tubular member.

A heart valve replacement device comprises a stent having a first end, a second end, an outer surface, and an inner surface, the inner surface defining a lumen; and a valve disposed within the lumen of the stent, the valve formed from a single sheet of tissue, the valve having an outer surface, an inner surface, and a thickness between the outer surface and the inner surface, the valve comprising at least three leaflets, wherein, the valve is attached to the stent with minimal sutures. The leaflets are formed with a curvilinear surface.

An annuloplasty band is provided. The band is sized and configured to be attached to an annulus of a heart valve. Later, if needed, a cable may be attached to opposing ends of the annuloplasty band at connectors on each end of the band. This forms a more secure anchor and a closed shape of the band. A percutaneous TMVR or TTMR heart valve replacement may then be attached to the closed band using it as a framework for anchoring the valve.

Provided herein is a prosthetic heart valve device including a biocompatible and biodegradable metal frame comprising a proximal end, a distal end, and a sidewall therebetween, the sidewall having a plurality of openings therethrough. The device further includes a biocompatible and biodegradable polymeric heart valve having an annular portion attached at least one contact point to the proximal end of the frame and at least one leaflet attached to and extending distally from the annular portion.

The disclosure relates to heart valve prostheses with the reduced need of pacemaker implantation and / or improved means for positioning the replacement heart valve. A heart valve prosthesis is provided with a stent and at least one locator. The locator has an adapted design for positioning within a cusp of the native aortic valve for implantation at the native heart valve site. Placement of the locators within the cusps preferably prevents movement from the native heart valve site post-implantation, including proximal movement of the prosthesis into the left ventricle.

The invention relates to the technical field of medical data processing, and discloses a heart valve replacement postoperative hemodynamic simulation and curative effect evaluation processing system which comprises the steps that a preset standard artificial valve three-dimensional geometric model is used for replacing a valve area distorted due to metal artifacts in computed tomography data so as to generate a static computational domain grid, the method comprises the following steps: adding a time-varying quantity source item resistance coefficient in a Navier Stokes equation according to a cardiac cycle sequential logic, simulating a valve leaflet opening and closing physical effect under a static grid by adjusting a spatial unit fluid impedance attribute, and resolving a flow field, and establishing a virtual motion mechanism based on a momentum source item to replace complex dynamic grid reconstruction; and the numerical stability and clinical treatment time efficiency of simulation calculation are improved while the geometric boundary fidelity is ensured.

The invention relates to a tricuspid regurgitation control device for an orthogonal transcatheter heart valve prosthesis. The invention also relates to access and occluder devices, in particular heart valve regurgitation drums and optionally closure discs and / or tubular stents, for managing and providing intentional regurgitation levels within transcatheter heart valve substitutes and in particular orthogonally delivered transcatheter prosthetic heart valves, an orthogonal delivery transcatheter prosthetic heart valve has a first inner flow control member / valve, a second inner reflux control member, and an outer annular support frame with a compressible wire unit that facilitates flat folding along the z-axis and compression of the valve vertically along the y-axis or orthogonal to the central axis of the flow control member, the present invention relates to a valvular delivery and deployment system, in particular to a valvular delivery and deployment system, which allows delivery and deployment of very large diameter valves from the inferior or superior vena cava to the tricuspid valve or trans-atrial delivery and deployment to the mitral valve, the valves having a height of about 5-60 mm and a diameter of about 25-80 mm, without extra-large diameter catheters and without delivery and deployment from catheters at acute access angles.

The invention discloses a heart valve stent material and a preparation method thereof. The preparation method comprises the following steps: performing decellularization treatment on biological tissues; soaking the biological tissue subjected to decellularization treatment in a cross-linking solution, and carrying out a cross-linking reaction; the cross-linking solution is an AMAS cross-linking solution or a BMPS cross-linking solution; and after the cross-linking reaction is completed, cleaning and drying the biological tissue to obtain the heart valve stent material. Through the mode, the preparation method of the heart valve stent material provided by the invention can be used for preparing the heart valve stent material with excellent biocompatibility and excellent mechanical property, effectively reduces the immune reaction risk, can well adapt to the complex mechanical environment of the heart, opens up a brand new path for the field of the heart valve stent material, and has wide application prospects. The heart valve replacement operation effect is expected to be greatly improved, and the prognosis condition of a patient is remarkably improved.

The present application provides a heart valve replacement device, system and artificial valve anchoring method, the heart valve replacement device comprises a ring-shaped support, a leaflet structure arranged on the inner surface of the ring-shaped support along the circumferential direction of the ring-shaped support, a first clamping member and a second clamping member arranged on the outer surface of the ring-shaped support along the axial direction of the ring-shaped support, wherein the ring-shaped support can be radially contracted or expanded, and the first clamping member and the second clamping member can cooperatively clamp the native leaflet of the heart, so that the leaflet structure is positioned relative to the native valve of the heart. Therefore, the present application can provide better artificial valve positioning effect, so as to improve the success rate of valve replacement surgery.

To provide a catheter with a suitable integrated embolic protection device. [Solution] The artificial heart valve delivery catheter includes an embolic filter to provide integrated embolic protection to prevent the release of embolus into the aorta, aortic arch, or branch vessels and other vascular systems during transvascular heart valve replacement procedures. The embolic filter will typically be fixed or movably attached to the shaft of the delivery catheter proximal to the artificial heart valve.

The utility model relates to an artificial valve anchoring device, a delivery system and a transcatheter heart valve replacement system, the device can radially collapse and expand between a radial collapse structure and a radial expansion structure, and the device comprises a skirt edge part, a main body part and a plurality of connecting pieces; the skirt edge part extends outwards in the radial direction in an umbrella disc shape, and the small-diameter end of the skirt edge part is connected with the main body part; the main body part comprises a plurality of grid units which are connected with one another; the connecting piece is arranged at the far end of the skirt edge part and used for being connected with a conveying device. At least part of the section of the connecting piece is configured to be an elastic deformation section, the elastic deformation section can be in a straightened state in a conveying state and gradually recover to be in a preset nonlinear shape in a release state, and gradual release of the artificial valve anchoring device can be achieved through gradual deformation of the elastic deformation section.

A system for heart valve replacement includes a collapsible and expandable replacement heart valve and a packaging assembly for storing the replacement heart valve. The packaging assembly includes a funnel extending from a first end to a second end. The funnel has a first interior diameter at the first end and a second interior diameter, the second interior diameter smaller than the first interior diameter. The funnel defines an internal lumen extending between the first and second ends. The funnel defines a plurality of longitudinal slots extending along an interior surface of the funnel between the first and second ends.

This document provides devices and methods for the treatment of heart conditions. For example, this document provides prosthetic heart valves and transcatheter heart valve replacement methods. The prosthetic heart valves can be configured into a low-profile configuration for containment within a small diameter delivery sheath. The prosthetic heart valves include can include a valve member attached to a stent frame. In some embodiments, the valve member is a molded biomaterial with a novel shape and resulting performance characteristics. Localized protective covering members can be attached to the stent frame to prevent the valve member from contacting the stent frame as the valve member cycles between its open and closed configurations.

The present invention relates to an access and occluder device, in particular a heart valve regurgitation drum and optional occlusion disc and / or annular stent for managing and providing a level of intentional regurgitation in a transcatheter heart valve replacement, in particular an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a first inner regurgitation control component and an outer annular support frame having compressible wire cells.SOLUTION: The compressible wire cells facilitate folding flat along the z-axis and compressing the valves vertically along the y-axis or orthogonal to the central axes of the flow control components, enabling the delivery and placement of very large diameter valves from the inferior or superior vena cavae to the tricuspid valves or transatrially to the mitral valves, having heights of about 5 to 60mm and diameters of about 25 to 80mm, without the need for an oversized catheter and without the need for delivery and placement from a catheter with a sharp approach angle.SELECTED DRAWING: Figure 3

The application discloses a mitral valve replacement prosthesis and an outer support thereof, and belongs to the field of heart valve replacement prostheses. The outer support comprises, from top to bottom, an atrial fixation section located in an atrium, a mitral valve annulus blocking section and a mitral valve replacement prosthesis inner support connecting section located in a ventricle. The upper edge of the atrial fixation section and the lower edge of the inner support connecting section are circular or quasi-circular. The cross section of the mitral valve annulus blocking section is a wavy D-shaped structure. The connecting rods in the inner support connecting section comprise at least one wavy connecting rod. At least two identical or two different mark points are arranged on the petal structure of the atrial fixation section. The wavy D-shaped structure and the wavy rectangular structure are arranged, so that the circumferential rotation and the up-and-down displacement are effectively prevented, and the service life of the prosthesis is improved. The elastic wavy connecting rod is arranged, so that the production and processing success rate is improved and the service life is prolonged. The mark points are increased, so that the prosthesis is more easily identified during surgery, and the surgery efficiency and success rate are improved.

A system for heart valve replacement surgery includes a guidewire and an elongated member. The elongated member has a side port located proximally at a distal apex of the elongated member. The guidewire is slidably disposed within a first lumen of the elongated member and configured to extend from the side port near the leaflet of the patient's natural heart valve. The side port includes an angled wall at its distal end, the angled wall being configured such that when the guidewire extends from the side port, it extends outward at an angle relative to the elongated member.

A template for a valve construct for replacement of at least one of a mitral valve and a tricuspid valve includes at least an anterior leaflet portion and at least a posterior leaflet portion, each leaflet portion having a proximal edge, a distal edge, and side edges extending between the proximal edge and the distal edge. The template further includes a plurality of substantially straight elongated chordae portions each having a proximal end connected to the distal edge of one of the at least two leaflet portions and a distal end extending therefrom and one or more papillary muscle head portions formed at a commissure between distal ends of at least two of the plurality of chordae portions. A total width of the leaflet portions of the template is substantially equal to a circumference of a native annulus of a heart valve.

The invention relates to an artificial heart valve and a transcatheter heart valve replacement system. The artificial heart valve comprises a valve stent, a first sealing element, a second sealing element and an elastic contraction element, the valve stent is sequentially provided with a plurality of grid groups which are arranged in the circumferential direction from the outflow end to the inflow end; the first sealing element covers the outer surface of the valve stent and at least covers the at least two grid groups close to the inflow end; the second sealing element is arranged outside the first sealing element, one end of the second sealing element is fixed outside the valve stent, and the other end of the second sealing element is folded from the inflow end to the inner side of the valve stent and fixed; the second sealing element can axially move along with the change of the radial size of the valve stent and always covers the inflow end; the elastic contraction elements are arranged in multiple rows in the circumferential direction of the valve stent, and each row comprises at least one elastic contraction element extending in the axial direction; the elastic contraction element can contract in the expansion state of the valve support and drive the second sealing piece to form a three-dimensional structure which continuously fluctuates in the circumferential direction.

The invention is a divisional application, and the application number of the original application is 202511455280. X. The invention relates to an artificial heart valve and a transcatheter heart valve replacement system.The artificial heart valve comprises a valve support and an outer skirt part, the valve support is provided with an inflow end and an outflow end, and the valve support is sequentially provided with a plurality of grid sets arranged in the circumferential direction from the outflow end to the inflow end; wherein the grid group closest to the inflow end is suitable for being matched with the position below the annulus plane, and the size of a net opening of at least one non-end grid group matched with the annulus plane is larger than that of a net opening of at least one axially adjacent grid group; the outer skirt part covers the outer surface of the valve stent, the outer skirt part at least covers the two adjacent grid groups close to the inflow end, and the position, close to the inflow end, of the outer skirt part is configured to be of a structure with the thickness gradually increased in the direction from the outflow end to the inflow end; at least one side of the outer skirt part corresponding to the non-end grid group in direct contact with the valve ring is provided with a liquid absorption expansion material, and the liquid absorption expansion material is configured to absorb blood and slowly expand after implantation so as to adapt to the structure of the valve ring; in a delivery state of the prosthetic heart valve, the imbibition swellable material is compressed and disposed in a mesh opening of the non-end mesh here to reduce a radial dimension of the prosthetic heart valve in a compressed state.

Some embodiments described herein include a heart valve replacement system that may be delivered to a targeted native heart valve site via one or more delivery catheters. In some embodiments, a prosthetic heart valve of the system includes structural features that securely anchor the prosthetic heart valve to the site of the native heart valve. Such structural features can provide robust migration resistance. In particular implementations, the prosthetic heart valves occupy a smaller delivery profile, thereby facilitating a smaller delivery catheter for advancement to the heart.

The utility model relates to the technical field of medical instruments, and discloses a supporting device used after heart valve replacement, which comprises a membrane body and is characterized in that a plurality of membrane body movable columns are fixedly connected outside the membrane body, three fixing rings are fixedly connected outside the membrane body movable columns, and the membrane body movable columns are fixedly connected with the fixing rings. The exteriors of the three fixing rings are fixedly connected with connecting supporting plates, the two ends of each connecting supporting plate are fixedly connected with a plurality of external fixing metal wire meshes, and the interiors of the external fixing metal wire meshes are fixedly connected with external metal net frames; the front ends of the multiple external fixed metal wire meshes are fixedly connected with external movable metal wires. According to the utility model, the membrane body is fixed through the internal metal net rack and the internal metal wire net, and the membrane body is fixed through the clamping plate formed by the external fixed metal wire net and the external metal net rack, so that the problem that the stability of the valve is reduced due to the fact that the supporting structure is not firm enough is solved.

A heart valve repair device may include a support configured to extend through a native annulus of a native heart valve, wherein the support comprises an upstream portion and a downstream portion; an annular expandable retainer extending from the upstream portion of the support, and an arm extending from the downstream portion of the support. The annular expandable retainer may include a C-shaped cross-section that is open inwardly. The arm may be configured to reach behind a leaflet of the native heart valve and sandwich the leaflet between the arm and the support.