32 results about "Heart valve replacement" patented technology

The application provides a heart valve positioning device, which comprises a first curved structure, a second curved structure, and a third curved structure. The first curved structure forms a spiral curved structure with a first size in a released state. The second curved structure forms a spiral curved structure with a second size in a released state, and the second size is greater than the first size. The second curved structure has a hollow first cavity for the first curved structure to pass through, forming the third curved structure. The distal end of the third curved structure is a free end, and the proximal end is connected with a delivery system. The third curved structure forms a spiral curved structure with a third size in a released state, and the first size is less than the third size and less than or equal to the second size. The embodiment of the application can reduce left ventricular outflow tract obstruction caused by large-scale movement of the anterior leaflet.

The present application relates to a kind of trans-catheter heart valve replacement system, which is composed of artificial heart valve and valve anchoring device, wherein the valve anchoring device can be wrapped outside valve chordae tendineae, while capturing native valve leaflet, providing positioning point for subsequent implantation of artificial heart valve;Artificial heart valve can be implanted in heart, and replace the physiological function of native valve.The valve anchoring device and artificial heart valve can be matched and positioned, in order to prevent the two from being too tight and continuous extrusion, friction and causing chordae tendineae rupture, there are two kinds of cooperation between them: the first cooperation state, can let artificial heart valve and valve anchoring device abut each other, ensure the stability of structure and position when the two are matched with each other;Second cooperation state, there is gap between artificial heart valve and valve anchoring device at this time, so that native valve leaflet or chordae tendineae can pass through, to reduce the contact area between valve replacement system and chordae tendineae as much as possible, avoid extruding chordae tendineae.

A heart valve replacement device comprises a stent having a first end, a second end, an outer surface, and an inner surface, the inner surface defining a lumen; and a valve disposed within the lumen of the stent, the valve formed from a single sheet of tissue, the valve having an outer surface, an inner surface, and a thickness between the outer surface and the inner surface, the valve comprising at least three leaflets, wherein, the valve is attached to the stent with minimal sutures. The leaflets are formed with a curvilinear surface.

Heart valve prosthesis delivery devices and methods. The devices include a delivery catheter and stabilization catheter. The stabilization catheter has expandable anchoring segments to anchor the device at a cardiac site superior to the implantation site of the heart valve prosthesis. The stabilization catheter also has a tubular assembly that includes an outer tubular member and an inner tubular member translationally displaceable within the outer tubular member. The outer tubular member defines a longitudinally extending slit and the inner tubular member defines an aperture positionable within the longitudinally extending slot. The device includes a snare and the location of the distal end of the snare adjacent to the distal portion of the delivery catheter is adjustable via translational displacement of the inner tubular member relative to the outer tubular member.

A heart valve replacement device comprises a stent having a first end, a second end, an outer surface, and an inner surface, the inner surface defining a lumen; and a valve disposed within the lumen of the stent, the valve formed from a single sheet of tissue, the valve having an outer surface, an inner surface, and a thickness between the outer surface and the inner surface, the valve comprising at least three leaflets, wherein, the valve is attached to the stent with minimal sutures. The leaflets are formed with a curvilinear surface.

An annuloplasty band is provided. The band is sized and configured to be attached to an annulus of a heart valve. Later, if needed, a cable may be attached to opposing ends of the annuloplasty band at connectors on each end of the band. This forms a more secure anchor and a closed shape of the band. A percutaneous TMVR or TTMR heart valve replacement may then be attached to the closed band using it as a framework for anchoring the valve.

Provided herein is a prosthetic heart valve device including a biocompatible and biodegradable metal frame comprising a proximal end, a distal end, and a sidewall therebetween, the sidewall having a plurality of openings therethrough. The device further includes a biocompatible and biodegradable polymeric heart valve having an annular portion attached at least one contact point to the proximal end of the frame and at least one leaflet attached to and extending distally from the annular portion.

The disclosure relates to heart valve prostheses with the reduced need of pacemaker implantation and / or improved means for positioning the replacement heart valve. A heart valve prosthesis is provided with a stent and at least one locator. The locator has an adapted design for positioning within a cusp of the native aortic valve for implantation at the native heart valve site. Placement of the locators within the cusps preferably prevents movement from the native heart valve site post-implantation, including proximal movement of the prosthesis into the left ventricle.

The invention relates to the technical field of medical data processing, and discloses a heart valve replacement postoperative hemodynamic simulation and curative effect evaluation processing system which comprises the steps that a preset standard artificial valve three-dimensional geometric model is used for replacing a valve area distorted due to metal artifacts in computed tomography data so as to generate a static computational domain grid, the method comprises the following steps: adding a time-varying quantity source item resistance coefficient in a Navier Stokes equation according to a cardiac cycle sequential logic, simulating a valve leaflet opening and closing physical effect under a static grid by adjusting a spatial unit fluid impedance attribute, and resolving a flow field, and establishing a virtual motion mechanism based on a momentum source item to replace complex dynamic grid reconstruction; and the numerical stability and clinical treatment time efficiency of simulation calculation are improved while the geometric boundary fidelity is ensured.

The invention discloses a heart valve stent material and a preparation method thereof. The preparation method comprises the following steps: performing decellularization treatment on biological tissues; soaking the biological tissue subjected to decellularization treatment in a cross-linking solution, and carrying out a cross-linking reaction; the cross-linking solution is an AMAS cross-linking solution or a BMPS cross-linking solution; and after the cross-linking reaction is completed, cleaning and drying the biological tissue to obtain the heart valve stent material. Through the mode, the preparation method of the heart valve stent material provided by the invention can be used for preparing the heart valve stent material with excellent biocompatibility and excellent mechanical property, effectively reduces the immune reaction risk, can well adapt to the complex mechanical environment of the heart, opens up a brand new path for the field of the heart valve stent material, and has wide application prospects. The heart valve replacement operation effect is expected to be greatly improved, and the prognosis condition of a patient is remarkably improved.

To provide a catheter with a suitable integrated embolic protection device. [Solution] The artificial heart valve delivery catheter includes an embolic filter to provide integrated embolic protection to prevent the release of embolus into the aorta, aortic arch, or branch vessels and other vascular systems during transvascular heart valve replacement procedures. The embolic filter will typically be fixed or movably attached to the shaft of the delivery catheter proximal to the artificial heart valve.

The utility model relates to an artificial valve anchoring device, a delivery system and a transcatheter heart valve replacement system, the device can radially collapse and expand between a radial collapse structure and a radial expansion structure, and the device comprises a skirt edge part, a main body part and a plurality of connecting pieces; the skirt edge part extends outwards in the radial direction in an umbrella disc shape, and the small-diameter end of the skirt edge part is connected with the main body part; the main body part comprises a plurality of grid units which are connected with one another; the connecting piece is arranged at the far end of the skirt edge part and used for being connected with a conveying device. At least part of the section of the connecting piece is configured to be an elastic deformation section, the elastic deformation section can be in a straightened state in a conveying state and gradually recover to be in a preset nonlinear shape in a release state, and gradual release of the artificial valve anchoring device can be achieved through gradual deformation of the elastic deformation section.

A system for heart valve replacement includes a collapsible and expandable replacement heart valve and a packaging assembly for storing the replacement heart valve. The packaging assembly includes a funnel extending from a first end to a second end. The funnel has a first interior diameter at the first end and a second interior diameter, the second interior diameter smaller than the first interior diameter. The funnel defines an internal lumen extending between the first and second ends. The funnel defines a plurality of longitudinal slots extending along an interior surface of the funnel between the first and second ends.

This document provides devices and methods for the treatment of heart conditions. For example, this document provides prosthetic heart valves and transcatheter heart valve replacement methods. The prosthetic heart valves can be configured into a low-profile configuration for containment within a small diameter delivery sheath. The prosthetic heart valves include can include a valve member attached to a stent frame. In some embodiments, the valve member is a molded biomaterial with a novel shape and resulting performance characteristics. Localized protective covering members can be attached to the stent frame to prevent the valve member from contacting the stent frame as the valve member cycles between its open and closed configurations.

The present invention relates to an access and occluder device, in particular a heart valve regurgitation drum and optional occlusion disc and / or annular stent for managing and providing a level of intentional regurgitation in a transcatheter heart valve replacement, in particular an orthogonally delivered transcatheter prosthetic heart valve having a first inner flow control component / valve, a first inner regurgitation control component and an outer annular support frame having compressible wire cells.SOLUTION: The compressible wire cells facilitate folding flat along the z-axis and compressing the valves vertically along the y-axis or orthogonal to the central axes of the flow control components, enabling the delivery and placement of very large diameter valves from the inferior or superior vena cavae to the tricuspid valves or transatrially to the mitral valves, having heights of about 5 to 60mm and diameters of about 25 to 80mm, without the need for an oversized catheter and without the need for delivery and placement from a catheter with a sharp approach angle.SELECTED DRAWING: Figure 3

The application discloses a mitral valve replacement prosthesis and an outer support thereof, and belongs to the field of heart valve replacement prostheses. The outer support comprises, from top to bottom, an atrial fixation section located in an atrium, a mitral valve annulus blocking section and a mitral valve replacement prosthesis inner support connecting section located in a ventricle. The upper edge of the atrial fixation section and the lower edge of the inner support connecting section are circular or quasi-circular. The cross section of the mitral valve annulus blocking section is a wavy D-shaped structure. The connecting rods in the inner support connecting section comprise at least one wavy connecting rod. At least two identical or two different mark points are arranged on the petal structure of the atrial fixation section. The wavy D-shaped structure and the wavy rectangular structure are arranged, so that the circumferential rotation and the up-and-down displacement are effectively prevented, and the service life of the prosthesis is improved. The elastic wavy connecting rod is arranged, so that the production and processing success rate is improved and the service life is prolonged. The mark points are increased, so that the prosthesis is more easily identified during surgery, and the surgery efficiency and success rate are improved.

A system for heart valve replacement surgery includes a guidewire and an elongated member. The elongated member has a side port located proximally at a distal apex of the elongated member. The guidewire is slidably disposed within a first lumen of the elongated member and configured to extend from the side port near the leaflet of the patient's natural heart valve. The side port includes an angled wall at its distal end, the angled wall being configured such that when the guidewire extends from the side port, it extends outward at an angle relative to the elongated member.

A template for a valve construct for replacement of at least one of a mitral valve and a tricuspid valve includes at least an anterior leaflet portion and at least a posterior leaflet portion, each leaflet portion having a proximal edge, a distal edge, and side edges extending between the proximal edge and the distal edge. The template further includes a plurality of substantially straight elongated chordae portions each having a proximal end connected to the distal edge of one of the at least two leaflet portions and a distal end extending therefrom and one or more papillary muscle head portions formed at a commissure between distal ends of at least two of the plurality of chordae portions. A total width of the leaflet portions of the template is substantially equal to a circumference of a native annulus of a heart valve.

The invention relates to an artificial heart valve and a transcatheter heart valve replacement system. The artificial heart valve comprises a valve stent, a first sealing element, a second sealing element and an elastic contraction element, the valve stent is sequentially provided with a plurality of grid groups which are arranged in the circumferential direction from the outflow end to the inflow end; the first sealing element covers the outer surface of the valve stent and at least covers the at least two grid groups close to the inflow end; the second sealing element is arranged outside the first sealing element, one end of the second sealing element is fixed outside the valve stent, and the other end of the second sealing element is folded from the inflow end to the inner side of the valve stent and fixed; the second sealing element can axially move along with the change of the radial size of the valve stent and always covers the inflow end; the elastic contraction elements are arranged in multiple rows in the circumferential direction of the valve stent, and each row comprises at least one elastic contraction element extending in the axial direction; the elastic contraction element can contract in the expansion state of the valve support and drive the second sealing piece to form a three-dimensional structure which continuously fluctuates in the circumferential direction.

The invention is a divisional application, and the application number of the original application is 202511455280. X. The invention relates to an artificial heart valve and a transcatheter heart valve replacement system.The artificial heart valve comprises a valve support and an outer skirt part, the valve support is provided with an inflow end and an outflow end, and the valve support is sequentially provided with a plurality of grid sets arranged in the circumferential direction from the outflow end to the inflow end; wherein the grid group closest to the inflow end is suitable for being matched with the position below the annulus plane, and the size of a net opening of at least one non-end grid group matched with the annulus plane is larger than that of a net opening of at least one axially adjacent grid group; the outer skirt part covers the outer surface of the valve stent, the outer skirt part at least covers the two adjacent grid groups close to the inflow end, and the position, close to the inflow end, of the outer skirt part is configured to be of a structure with the thickness gradually increased in the direction from the outflow end to the inflow end; at least one side of the outer skirt part corresponding to the non-end grid group in direct contact with the valve ring is provided with a liquid absorption expansion material, and the liquid absorption expansion material is configured to absorb blood and slowly expand after implantation so as to adapt to the structure of the valve ring; in a delivery state of the prosthetic heart valve, the imbibition swellable material is compressed and disposed in a mesh opening of the non-end mesh here to reduce a radial dimension of the prosthetic heart valve in a compressed state.

The utility model relates to the technical field of medical instruments, and discloses a supporting device used after heart valve replacement, which comprises a membrane body and is characterized in that a plurality of membrane body movable columns are fixedly connected outside the membrane body, three fixing rings are fixedly connected outside the membrane body movable columns, and the membrane body movable columns are fixedly connected with the fixing rings. The exteriors of the three fixing rings are fixedly connected with connecting supporting plates, the two ends of each connecting supporting plate are fixedly connected with a plurality of external fixing metal wire meshes, and the interiors of the external fixing metal wire meshes are fixedly connected with external metal net frames; the front ends of the multiple external fixed metal wire meshes are fixedly connected with external movable metal wires. According to the utility model, the membrane body is fixed through the internal metal net rack and the internal metal wire net, and the membrane body is fixed through the clamping plate formed by the external fixed metal wire net and the external metal net rack, so that the problem that the stability of the valve is reduced due to the fact that the supporting structure is not firm enough is solved.

The present application relates to a kind of artificial heart valve and transcatheter heart valve replacement system, the artificial heart valve described above includes valve support and outer skirt, valve support has inflow end and outflow end, valve support is successively provided with multiple circumferentially arranged grid groups from outflow end to inflow end, wherein the grid group closest to inflow end is adapted to match below annulus plane position, and the mesh size of at least one group of non-end grid group matching annulus plane is greater than the mesh size of at least one grid group adjacent to it in axial direction;Outer skirt is covered on the outer surface of valve support, outer skirt covers at least adjacent two groups of grid groups close to inflow end, and outer skirt is configured as the structure of increasing thickness in the direction from outflow end to inflow end at the position close to inflow end.

The application discloses an adjustable heart valve replacement system, which comprises a single-layer self-expanding valve support and a spherical self-expanding anchoring support. The single-layer self-expanding valve support has a circumferential main support and a skirt support, the skirt support is integrally formed at an atrium end of the circumferential support, and the anchoring support is detachably abutted on the skirt support. The anchoring support can be adjusted in size according to different hearts, so that the anchoring support can adapt to different atrium sizes of patients, and thus a better treatment effect can be achieved. The valve support and the anchoring support can be delivered in a detachable mode, so that a thinner catheter can be used to deliver and implant into a human body, and the expansion of the blood vessel can be reduced.

The application belongs to the technical field of medical devices, and particularly relates to a heart valve replacement system, which comprises: a valve support, the valve support is a single-layer self-expanding structure, the valve support comprises a support body and a skirt structure which are integrally connected from an outflow end to an inflow end; and an anchoring support, the anchoring support is a spherical structure, the anchoring support is located on the inner side of the skirt structure and is detachably abutted on the skirt structure. The valve support of the application is a single-layer self-expanding support, the single-layer structure is conducive to compression and delivery, the valve support and the anchoring support are a detachable structure, so that they can be delivered separately, the compression diameter is small, and the delivery and implantation through the femoral artery and the like are facilitated, the two are delivered separately and are sequentially introduced into the human body, a thinner catheter can be used for delivery and implantation into the human body, and the expansion of the blood vessel is reduced.

Heart valve replacement often involves complications associated with paravalvular leaks. Vascular plug and occlusive devices, as well as heart valves particularly beneficial in treating the phenomenon of paravalvular leaks are described to address this issue.

A system for use at an annulus of a valve of a heart of a subject comprises an implant and an implant-positioning device. The implant comprises (i) a wire; (ii) multiple anchors, slidably mounted in series along the wire, each of the anchors having: a slot through which the wire is threaded, and a pointy front end; and (iii) multiple tubes, the wire being threaded through each of the tubes such that the multiple tubes are slidably mounted on the wire alternatingly with the multiple anchors. The implant-positioning device is configured to implant the implant in the heart with the wire positioned along the annulus by, for each of the anchors: (i) positioning the anchor at the annulus, and (ii) using a deployment mechanism of the implant-positioning device, driving the pointy front end of the anchor into the annulus. Other embodiments are also described.

Some embodiments described herein include a heart valve replacement system that may be delivered to the targeted heart valve site via a delivery catheter. In some embodiments, the heart valve replacement system can assemble a valve device after the valve device is delivered to the heart. In some embodiments, heart valve replacement system includes two anterior flaps that are separate but overlap each other.

Prosthetic heart valve devices and associated methods for percutaneous or transcatheter heart valve replacement are disclosed herein. A heart valve prosthesis configured in accordance herewith includes a frame having a valve support and a plurality of support arms extending therefrom. The plurality of support arms may include a main support arm configured to extend from the valve support for capturing at least a portion of a valve leaflet of a native heart valve therebetween when the valve prosthesis is in an expanded configuration and deployed within the native heart valve. In addition, the plurality of support arms may include multiple supplemental support arms disposed about the circumference of the valve support that when deployed in the expanded configuration are configured to at least partially engage subannular tissue at the native heart valve.

An annuloplasty band is provided. The band is sized and configured to be attached to an annulus of a heart valve. Later, if needed, a cable may be attached to opposing ends of the annuloplasty band at connectors on each end of the band. This forms a more secure anchor and a closed shape of the band. A percutaneous TMVR or TTMR heart valve replacement may then be attached to the closed band using it as a framework for anchoring the valve.

Embodiments herein relate to bioprosthetic heart valves. In an embodiment, a heart valve replacement system is included having a delivery catheter can include a heart valve accommodation region; and a heart valve disposed around the delivery catheter at the heart valve accommodation region of the delivery catheter, the heart valve can include a frame; and a plurality of valve leaflets coupled to the frame; wherein the valve leaflets include an animal tissue, the animal tissue can include from 15% to 50% by weight water; and from 20% to 70% by weight glycerol; a package defining an interior volume, wherein the delivery catheter and the heart valve are disposed within the package. Other embodiments are also included herein.