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233 results about "Catechin" patented technology

Catechin /ˈkætɪtʃɪn/ is a flavan-3-ol, a type of natural phenol and antioxidant. It is a plant secondary metabolite. It belongs to the group of flavan-3-ols (or simply flavanols), part of the chemical family of flavonoids.

Antibacterial and antioxidant composite film applied to food preservation and production method of antibacterial and antioxidant composite film

According to the antibacterial and antioxidant composite film applied to food preservation and the production method of the antibacterial and antioxidant composite film, the chlorogenic acid, the catechin, the montmorillonite and the zeolite are introduced, and a drying process is optimized, so that the antibacterial performance, the antioxidant performance and the mechanical performance of the preservative film are remarkably improved, and meanwhile, the water vapor permeability and the oxygen permeability are reduced. The method comprises the specific steps of raw material preparation, polyphenol compound and mineral substance preparation, membrane liquid preparation and treatment, drying process optimization and finished product membrane uncovering. According to the preparation method disclosed by the invention, components such as chlorogenic acid, catechin, montmorillonite and zeolite are introduced, and a drying process is optimized, so that the food preservative film with synergistic antibacterial and antioxidant properties is prepared.
Owner:厦门富锦新材料有限公司

Soil saline-alkali modifier as well as preparation method and application thereof

The invention belongs to the technical field of soil improvement, and relates to a soil saline-alkali improver as well as a preparation method and application thereof. The invention provides a soil saline-alkali modifier. The soil saline-alkali modifier is composed of a shell slow-release layer, a middle conditioning layer and an internal functional layer, the internal functional layer is prepared from a saline-alkali soil improving fungicide, biochar and a granulation adhesive; the middle conditioning layer is composed of a conditioner, a first slow-release agent and a first solvent; the shell slow-release layer is prepared from humic acid, furfural residues, a calcium ion compound, a second slow-release agent and a second solvent; the calcium ion compound is at least one of phosphogypsum, desulfurized gypsum, calcium chloride and calcium sulfate; the conditioner is at least one of coumarin, resveratrol and catechin. A multi-layer slow-release structure is constructed, through a multi-layer slow-release mode, all the improvement components make contact with the saline-alkali soil in sequence, and the excellent improvement effect is achieved.
Owner:CHINA SHAANXI HIGH STANDARD FARMLAND CONSTR GRP CO LTD

Biodegradable material as well as preparation method and application thereof

The invention relates to the technical field of polymer degradable materials, in particular to a biodegradable material as well as a preparation method and application thereof. The material takes modified polylactic acid as a main body, and an antioxidant, a plasticizer, a flame retardant and an inorganic filler are used as auxiliary materials in parts by weight. The method is characterized in that lactic acid and an epicatechin imidazole ammonium chloride polymer are polymerized under the catalysis of stannous octoate, and an epicatechin bioactive group is introduced into a polylactic acid main chain in a chemical bonding manner, so that the biodegradation rate, the mechanical property and the thermal stability of the material are remarkably improved. Bioactive substances and ionic groups in the material promote microbial degradation, and the material can be completely decomposed in a compost environment in a short time; meanwhile, the strength, the toughness and the high-temperature processability of the polylactic acid are effectively improved through molecular-level enhancement and an ionic cross-linking effect. The material can be widely applied to the fields of disposable tableware, food packaging films, degradable agricultural mulching films and the like.
Owner:HUNAN GREEN STAR NEW MATERIALS CO LTD

Coated hydrophobic polyphenol nanoparticles, preparation method therefor and application thereof

The present invention discloses coated hydrophobic polyphenol nanoparticles, preparation method therefor and application thereof. The preparation method for coated hydrophobic polyphenol nanoparticles includes: (1) obtaining a hydrophobic polyphenol nanoparticles suspension; (2) injecting a catechin aqueous solution and a metal salt aqueous solution into the hydrophobic polyphenol nanoparticles suspension to obtain a composite nanoparticles suspension; (3) removing excess catechin and metal ions from the composite nanoparticles suspension to obtain a coated hydrophobic polyphenol nanoparticles suspension. The present invention provides an application of the coated hydrophobic polyphenol nanoparticles in the preparation of pectin gel. The coated hydrophobic polyphenol nanoparticles exhibit significantly enhanced biological activity and long-term stability, developing a pectin gel with long-term stability.
Owner:ZHEJIANG UNIV OF TECH

Polyamide fiber with antibacterial performance and preparation method thereof

The invention relates to the technical field of antibacterial polyamide fiber preparation, and discloses a polyamide fiber with antibacterial performance and a preparation method thereof.The polyamide fiber is prepared from, by weight, 100 parts of PA6 slices, 10-15 parts of graphene oxide, 1-5 parts of surface amination mesoporous catechin-silver-loaded zirconium phosphate and related auxiliaries, after surface amination mesoporous catechin-silver-loaded zirconium phosphate and graphene oxide are subjected to amide linkage, the surface amination mesoporous catechin-silver-loaded zirconium phosphate and amide groups of polyamide fibers form a hydrogen bond network, the surface amination mesoporous catechin-silver-loaded zirconium phosphate and the amide groups of the polyamide fibers are mutually combined to play a synergistic effect, the interface binding energy is increased, and antibacterial components can stably exist in the polyamide fibers; meanwhile, the mesoporous structure provides multi-channel support, induces cracks to expand along the edge of a pore and increases the length of a fracture path, so that the stress transfer efficiency is obviously improved, and the problem of internal stress concentration caused by the addition of large-particle high-content rigid particles is avoided.
Owner:NANTONG JINYU TEXTILE PLASTIC CO LTD

Preparation method for enhancing inhibitory activity of lonicera caerulea juice xanthine oxidase through fermentation of plant lactobacillus

According to the preparation method disclosed by the invention, the whole fruit juice of the lonicera caerulea (which retains fruit residues) is fermented by virtue of the plant lactobacillus KLDS1.0391, KLDS1.0320 or KLDS1.0368, so that the xanthine oxidase (XO) inhibition activity is remarkably improved. After fermentation, the XO inhibition rate is increased to 48-50.87% (the content of unfermented juice is 31.21%), the total phenol content is increased by 15-24.3%, and the contents of main XO inhibitors in the lonicera caerulea: cyanidin-3-O-glucoside (IC50 = 115.28 [mu] M), cyanidin-3, 5-diglucoside (IC50 = 116.34 [mu] M), peonidin-3-glucoside (IC50 = 105.34 [mu] M), quercetin (IC50 = 88.75 [mu] M), catechin (IC50 = 110 [mu] M) and caffeoylquinic acid (IC50 = 250.35 [mu] M) are remarkably increased. Wherein the quercetin content is increased by 73.8% at most (KLDS1.0320 strain fermentation is performed for 24 hours), and the XO inhibition rate is increased from 31.21% to 50.87%. Technical support is provided for development of a natural XO inhibitor and a functional fermented beverage, so that a new thought is provided for functional fermented juice with lonicera caerulea as a key component.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

Stem cell culture medium and preparation method and application of stem cell exosome with oxidation resistance

The invention provides a stem cell culture medium and a preparation method and application of a stem cell exosome with oxidation resistance. The stem cell culture medium comprises baicalin, quercetin, liquiritin and catechin. According to the stem cell culture medium provided by the invention, a mixture of baicalin, quercetin, liquiritin and catechin is adopted as a component of the culture medium to stimulate the stem cells, and the oxidative stress state of the stem cells is changed, so that the stem cells can secrete exosomes with an antioxidant effect, and the secreted exosomes have higher antioxidant capacity. The corresponding stem cell exosome is relatively excellent in the aspect of oxidation resistance.
Owner:深圳泽医细胞治疗集团有限公司

Preparation method of lactoferrin-polyphenol nanocomposite with intestinal immune function

The invention discloses a preparation method of a lactoferrin-polyphenol nano compound with an intestinal immune function. The method comprises the following steps: firstly, moderately hydrolyzing lactoferrin under the action of compound protease, and optimizing a protein molecular structure; then, compounding with water-soluble polyphenol (such as chlorogenic acid or epicatechin) by utilizing a metal ion chelating technology, and inducing lactoferrin to be bridged and aggregated by Ca to form a compound; and then, carrying out ultrasonic homogenization treatment, and further controlling the particle size to enable the particle size to be distributed in a range of 100-300 nm. The obtained compound is subjected to nanofiltration concentration and electrostatic spray drying to obtain a shell-core nano compound with a stable structure, and nitrogen-filled packaging is adopted to prevent oxidation. The lactoferrin-polyphenol nano-composite prepared by the invention not only has good stability and intestinal immunity enhancement effect, but also has remarkable antibacterial activity, and can be widely applied to functional foods and nutritional health-care products.
Owner:JIANGNAN UNIV

A remediation composition for hexavalent chromium-contaminated soil and a soil remediation method

The present invention provides a remediation composition for soil contaminated with hexavalent chromium and a soil remediation method. The composition comprises catechin, flavonoid isorhamnetin and humic acid with a mass ratio of 1:1 - 3:0.1 - 1. The remediation composition for soil contaminated with hexavalent chromium according to the present invention can achieve a leaching rate of 93% for the hexavalent chromium contamination in the soil. At the same time, the composition can reduce more than 95% of the hexavalent chromium in the leaching solution to trivalent chromium with low toxicity, achieving the purpose of completely removing hexavalent chromium from the soil and greatly reducing the material cost of chemical leaching.
Owner:TIANJIN POLYTECHNIC UNIV

Formula composition applied to antioxidant and anti-aging food and production method of formula composition

The invention discloses a formula composition which is prepared from the following components in parts by weight: 100 to 400 parts by weight of grape seed procyanidine, 100 to 300 parts by weight of pomegranate polyphenol, 10 to 100 parts by weight of ergothioneine, 50 to 200 parts by weight of catechin and 100 to 400 parts by weight of astragalus polysaccharide. According to the invention, cell-level anti-aging is taken as a core logic, five active ingredients of grape seed procyanidine, pomegranate polyphenol, ergothioneine, catechin and astragalus polysaccharide are scientifically compounded, a multi-dimensional anti-oxidation defense system is constructed, and multiple effects of scavenging free radicals, repairing cell damage, delaying an aging process and the like can be realized.
Owner:SHANGHAI LANGSI ZHIYAO BIOTECHNOLOGY DEVELOPMENT CO LTD

High-color-fixation medium-temperature hole sealing agent for aluminum alloy anode oxide film and preparation method and application of high-color-fixation medium-temperature hole sealing agent

The invention belongs to the technical field of hole sealing reagents, and discloses a high-color-fixation medium-temperature hole sealing agent for an aluminum alloy anodic oxide film as well as a preparation method and application of the high-color-fixation medium-temperature hole sealing agent. The medium-temperature hole sealing agent comprises hole sealing main salt, hole sealing auxiliary salt, a color fixing auxiliary agent and an auxiliary agent, the hole sealing main salt comprises nickel acetate or nickel acetate hydrate; the hole sealing secondary salt comprises at least one of cobalt acetate, magnesium acetate, lithium acetate and calcium acetate; the color fixing auxiliary agent comprises at least one of tannic acid, gallic acid, quercetin, ellagic acid, tannic acid and catechin. According to the medium-temperature hole sealing agent, hole sealing of the aluminum alloy oxidation film is achieved under the medium-temperature (55-65 DEG C) condition, meanwhile, the color fixing process of dye molecules in micropores of the oxidation film is synchronously completed through the effect of the specific color fixing auxiliary, and the problems of uneven hole sealing and color fading caused by a separation technology are solved. And after the hole sealing agent is used for treatment, the binding force of the dye and an oxidation film can be enhanced, and the dye is not easy to fade in a high-temperature and high-humidity environment for a long time.
Owner:FOSHAN HAIHUA SURFACE TREATMENT TECH CO LTD

Application and use method of catechin, fertilizer preparation method and fertilizer

The invention discloses application of catechin as a nitrification inhibitor, a use method of catechin as a nitrification inhibitor, a preparation method of a fertilizer formed by the catechin and the fertilizer. According to indoor simulation and field plot and field experiments, the catechin shows a good inhibition effect on soil ammonia oxidizing bacteria when the dosage per mu is 40.0-100.0 g, conversion from ammonium nitrogen to nitrate nitrogen can be effectively delayed, and compared with a traditional nitrification inhibitor, the catechin has the advantage in the later stage of nitrification inhibition.
Owner:SHENYANG INST OF APPL ECOLOGY CHINESE ACAD OF SCI

Catechin-beta-cyclodextrin oleate nanoparticle inclusion compound and preparation method thereof

The invention discloses a catechin-beta-cyclodextrin oleate nanoparticle inclusion compound (CAT-CDO) and a preparation method thereof.The preparation method comprises the steps that a 75% ethanol water solution is added into beta-cyclodextrin oleate (CAT), catechin is dissolved in 20 mL of ethanol solution, the catechin solution is dropwise added into a CAT solution at the temperature of 30 DEG C in a dark place, and a reaction is conducted under stirring; centrifuging the mixed solution to remove undissolved solids, so as to obtain a supernatant which is an inclusion compound solution; and freeze-drying the inclusion compound solution to obtain inclusion compound solid powder. The CAT-CDO prepared by the invention has a good solubilizing effect on CAT, and the antioxidant stability, the release performance, the photo-thermal stability and the cytotoxicity of the CAT are effectively improved. Besides, catechin can be replaced by any other phenolic compounds, and the phenolic compounds and CDO are prepared into a nanoparticle inclusion compound, so that the effects of solubility, antioxidant stability and the like of phenolic substances are improved, and the application performance of the phenolic substances in various fields is further improved.
Owner:GUIZHOU PROVINCIAL MODERN AGRI DEV RES INST (GUIZHOU PROVINCIAL MODERN RURAL DEV RES CENT GUIZHOU PROVINCIAL RES INST OF RURAL ECONOMIC & SOCIAL DEV GUIZHOU PROVINCIAL AGRI PROD PROCESSING RES INST)

A blueberry puree prepared by cryogenic grinding and oxidation isolation

The invention relates to the technical field of blueberry puree preparation, and relates to a blueberry puree prepared based on cryogenic grinding, oxidation and isolation. The blueberry puree comprises the following components in parts by weight: 90-100 parts by weight of blueberries, 0.1-0.5 parts by weight of a composite stabilizer, 1-5 parts by weight of a honey protective agent, 0.03-0.05 parts by weight of an L-cysteinease inhibitor, and 0.3-0.7 parts by weight of a citric acid buffer. The composite stabilizer is obtained by mixing phytic acid, sodium pyrophosphate, and modified catechin in a ratio of 1:0.2-0.6:1-3, and the modified catechin is prepared by a glycosylation reaction of catechin and rhamnose in the presence of a rhamnosyltransferase catalyst. The composite stabilizer is used to improve the antioxidant capacity and the ability to stabilize active components in the blueberry puree preparation process, thereby extending the shelf life. At the same time, the cryogenic grinding, oxidation and isolation preparation technology is used to retain the nutrients and active substances in the blueberries to the greatest extent, thereby ensuring the high quality of the product.
Owner:DAXINGANLING YIKANG WILD FOOD PROCESSING CO LTD

Multi-effect analgesic and anti-inflammatory gel for oral cavity and preparation method thereof

The invention discloses oral multi-effect analgesic and anti-inflammatory gel and a preparation method thereof, and belongs to the technical field of medical gel. The gel is prepared from mussel mucin grafted hydroxypropyl chitosan, a poly (N-isopropylacrylamide)-co-acrylic acid copolymer, quercetin-zinc coordination nanoparticles, a local anesthetic compound wrapped by temperature-sensitive lipidosome, a gamma-polyglutamic acid-catechin gel matrix, aloe polysaccharide, dipotassium glycyrrhizinate, and sodium hyaluronate and potassium sorbate which can be selectively added, wherein the local anesthetic compound is prepared from the mussel mucin grafted hydroxypropyl chitosan, the poly (N-isopropylacrylamide)-co-acrylic acid copolymer, the quercetin-zinc coordination nanoparticles, the temperature-sensitive lipidosome, the gamma-polyglutamic acid-catechin gel matrix, the aloe polysaccharide and the dipotassium glycyrrhizinate. During preparation, part of the components and water are stirred to obtain a mixed solution, and then the other components are added and stirred into gel. According to the gel, the leakage rate of local anesthetics is reduced by stabilizing the liposome through the zinc ions, the quercetin adjusts the phase transition temperature of the liposome to realize preferential drug release at the pain part, the mussel mucin and the copolymer form a reversible hydrogen bond network to enhance the mucous membrane adhesive force, and the inflammatory environment triggers the gel permeation drug release, so that the gel has the advantages of multiple-effect synergy, strong adhesion and the like; the problems that existing oral gel is short in analgesia time and insufficient in anti-inflammation can be effectively solved.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV

Identification method for characteristic chromatograms of Bergenia ligulata medicinal materials, cut pieces, extracts and their formula granules

ActiveCN117451864BComponent separationBergenia ligulataMedicinal herbs
The present invention provides a method for identifying HPLC characteristic spectra of bergenia medicinal materials, decoction pieces, extracts and their formula particles, comprising the following steps: A) dissolving a test sample with a solvent, extracting, and obtaining a test solution; B) determining the test solution with high performance liquid chromatography to obtain HPLC characteristic spectra of bergenia medicinal materials, decoction pieces, extracts and their formula particles; the chromatographic conditions of the high performance liquid chromatography are: the chromatographic column is a C18 column; the mobile phase A is methanol, and the mobile phase B is a 0.1% phosphoric acid solution, and the gradient elution. The present invention adopts high performance liquid chromatography, selects methanol-0.1% phosphoric acid solution as the mobile phase for gradient elution, and uses arbutin, gallic acid, catechin, bergenin, and ellagic acid as reference substances to establish HPLC characteristic spectra of bergenia medicinal materials, decoction pieces, extracts and their formula particles, with good repeatability and precision, stable and reliable methods, and can control the quality of bergenia medicinal materials, decoction pieces, extracts and their formula particles.
Owner:SICHUAN NEO GREEN PHARMA TECH DEV

Large scale production of catechol-containing polymers

This invention relates to a method for manufacturing a catechol-containing co-polymer through a suspension polymerization or a solution polymerization process. In some illustrative embodiments, this disclosure relates to a process of a free radical suspension polymerization for large-scale manufacturing catechol-containing copolymers. In some other illustrative embodiments, this disclosure relates to a solution polymerization of free radical, cationic, or anionic process for large-scale manufacturing catechol-containing copolymers. The process and the product thereof are within the scope of this disclosure.
Owner:PURDUE RES FOUND

Oral Composition

The present invention provides an oral composition that can be used for anti-obesity, suppressing fat absorption, suppressing an increase in neutral fat, suppressing sugar absorption, suppressing an increase in blood sugar level, reducing body fat, or reducing BMI. An oral composition containing gallic acid and catechins, The oral composition has a mass ratio of gallic acid:catechins=1:0.1 to 5. The oral composition preferably further contains ellagic acid. It is also preferably used for anti-obesity, suppression of fat absorption, suppression of increase in neutral fat, suppression of sugar absorption, suppression of increase in blood glucose level, reduction of body fat, or reduction of BMI.
Owner:TOYO SHINYAKU KK

Fish and shellfish feed

To provide fish and shellfish feed, fish and shellfish feed additives, a method for producing fish and shellfish feed, and a method for raising fish and shellfish that can produce fish and shellfish in good health. [Solution] The following components (A) and (B): (A) Non-polymerized catechins 0.001-1.5% by mass (B) Oligosaccharides A fish and shellfish feed containing [this ingredient].
Owner:KAO CORP

A cleaning and passivation method for small-diameter grooved special-shaped copper wire

The present application belongs to the field of metal wire cleaning, and provides a cleaning and passivation method for special-shaped copper wire with grooves and small wire diameter; first, the copper wire is pre-blowed by an annular air knife to remove surface attachments, and is introduced into a groove guide water pipe; then, directional hot water consistent with the groove direction of the copper wire is used for strong flushing, and catechin gel mother liquor is added in the cleaning liquid and a brush is arranged for cooperative brushing; the copper wire is introduced into an ultrasonic cleaning tank for reciprocating deep purification, and the purified copper wire is introduced into a hot air duct arranged in the groove for deep dehydration and guide flow drying; the copper wire is introduced into a passivation chamber provided with an ultrasonic atomizer, and a passivation liquid containing a succinimidazole agent is atomized into uniform fine mist droplets to cover the copper wire; after the copper wire is finally dried by hot air, film formation and solidification are completed, and then the copper wire is wound, effectively solving the problems of difficult cleaning of special-shaped copper wire grooves and uneven passivation film, and improving the surface quality and oxidation resistance of the product.
Owner:浙江嘉杭机械科技有限公司

Characteristic chromatogram of platelet increasing capsule as well as construction method and application thereof

The invention discloses a platelet increasing capsule characteristic chromatogram and a construction method and application thereof, and belongs to the technical field of quality control of traditional Chinese medicine compound preparations. According to the method, 13 control components including gallic acid, catechin, paeoniflorin, forsythiaside B, benzoic acid, astragalus smicus glycoside, forsythin, arctiin, liquiritigenin, benzoyl paeoniflorin, paeonol, arctigenin and indirubin are selected, a high performance liquid chromatography-mass spectrometry technology is applied, multiple batches of preparation samples are analyzed, and the content of the components in the preparation samples is determined. And establishing a characteristic spectrum of the chemical components. Compared with a traditional method, the technology has good precision and reproducibility, the data result is accurate and reliable, meanwhile, the technology can identify the 13 components at the same time under the same chromatographic condition, the analysis efficiency is remarkably improved, synchronous monitoring of multiple effective components is achieved, and the consistency and stability of the preparation quality can be guaranteed.
Owner:SHAANXI UNIV OF SCI & TECH

MBBR (Moving Bed Biofilm Reactor) composite modified filler as well as preparation method and application thereof

The invention discloses an MBBR (Moving Bed Biofilm Reactor) composite modified filler as well as a preparation method and application thereof, the MBBR composite modified filler comprises the following raw material components in parts by mass: 5-15 parts of elemental iron-carbon powder, 80-95 parts of a framework material, 5-10 parts of a corrosion inhibition carbon source and 3-5 parts of paraffin oil, wherein the corrosion inhibition carbon source comprises modified chitosan and starch, and the mass ratio of the modified chitosan to the starch is (1.5-4): 1; the modified chitosan comprises chitosan, 2-hydroxy-1, 4-naphthoquinone which is grafted on the chitosan through a-C = N-bond, and catechin which is grafted on the 2-hydroxy-1, 4-naphthoquinone. The iron-carbon micro-electrolysis technology is combined with the MBBR process, so that the biodegradability of the refractory wastewater is improved, and the wastewater treatment effect of the MBBR process is improved.
Owner:NANJING GAOKE ENVIRONMENTAL TECH CO LTD

Application of catechin derivative WM-21 in preparation of neuroprotection and anti-neuroinflammation drugs

The invention discloses an application of a catechin derivative WM-21 in preparation of neuroprotection and anti-neuroinflammation drugs, and belongs to the technical field of biomedicines.The catechin derivative WM-21 is (2R, 3S)-2-(3, 4-dihydroxyphenyl)-6-((E)-styrene) chroane-3, 5, 7-triol (C22H19O6), and the chemical structural formula of the catechin derivative WM-21 is shown in the formula (I); the catechin derivative WM-21 provided by the invention has a neuroprotective effect on a plurality of nerve cells, has certain application potential in preparation of neuroprotective drugs, and is beneficial to prevention or alleviation of nervous system diseases. # imgabs0 #
Owner:SHENZHEN TECH UNIV

Construction method of specific chromatogram of Chinese patent medicine Zhikang capsule as well as specific chromatogram and application of specific chromatogram

The invention relates to a construction method of a specific chromatogram of a Chinese patent medicine Zhikang capsule, and the specific chromatogram and application thereof, and the method comprises the following steps: carrying out gradient elution by using a high performance liquid chromatograph, determining the contents of catechin, magnoflorine, berberine hydrochloride and 1, 4-di [4-(glucose oxygen) benzyl]-2-isobutyl malate, and forming the high performance liquid chromatography specific chromatogram of the Zhikang capsule. Nine characteristic peaks are determined as a characteristic chromatogram, main components such as alkaloids, phenols, anthraquinones and glycosides are covered, and a quality evaluation system of the Chinese patent medicine Zhikang capsule is constructed; the method is good in specificity, precision, repeatability and solution stability, and can be used for standardizing production of the Zhikang capsules and ensuring uniformity and stability of internal quality of products to provide comprehensive quality control.
Owner:XIAN CHIHO PHARMA

Method Of Treating, Reducing, Or Alleviating A Medical Condition In A Patient

A method of treating, reducing, or alleviating a medical condition in a patient includes administering to a patient in need thereof, a pharmaceutical composition comprising one or more antiviral medications together with an anti-vascular endothelial growth factor (anti-VEGF) medication and a rho-associated protein kinase (ROCK) inhibitor, the patient having at least one of a respiratory tract inflammatory disease, a central nervous system inflammatory disease, and vasculitis, the one or more antiviral medications preventing an attachment of viruses to cell walls, blocking a penetration of the viruses into cells, and / or inhibiting virus replication by damaging nucleic acids of the viruses, and the anti-VEGF medication and ROCK inhibitor treating an exhausted cellular immune response and inflammation of the patient. In one or more other embodiments, the pharmaceutical composition comprises one or more antiviral medications together with at least one of: (i) cannabidiol (CBD), (ii) linoleic acid, (iii) catechin, and (iv) metformin.
Owner:PEYMAN GHOLAM A

Application of catechin in promoting growth and development of rice and / or increasing yield of rice

PendingCN120052216ABiocidePlant growth regulatorsBiotechnologyNitrogen accumulation
The invention belongs to the technical field of rice cultivation, and particularly relates to application of catechin in promoting rice growth and development and / or increasing rice yield. The invention finds that catechin has the function of a biostimulant, and can effectively promote the growth and development of rice and increase the yield of rice. Planting tests show that by applying a proper amount of catechin to rice through root irrigation, direct field application along with base fertilizer or foliage spraying, growth of the overground part of the rice can be remarkably promoted, growth of the underground part of the rice can be promoted, the nitrogen accumulation amount of the rice is increased, the tiller number of the rice is increased, the yield of the rice is increased, and the effect is excellent.
Owner:HUAZHONG AGRI UNIV

Catechin-loaded auricularia fuscosuccinea polysaccharide-gelatin nanocapsule and preparation method thereof

The invention discloses a catechin-loaded auricularia fuscosuccinea polysaccharide-gelatin nanocapsule and a preparation method thereof. The preparation method comprises the following steps: dissolving auricularia fuscosuccinea polysaccharide and gelatin in ultrapure water to obtain an auricularia fuscosuccinea polysaccharide solution and a gelatin solution; adjusting the pH value; catechin is dissolved in absolute ethyl alcohol, and a catechin solution is obtained; adding the catechin solution into the auricularia fuscosuccinea polysaccharide solution, and stirring at room temperature to obtain an auricularia fuscosuccinea polysaccharide-catechin solution Dropwise adding the auricularia fuscosuccinea polysaccharide-catechin solution into a gelatin solution, and performing ultrasonic treatment in dark and ice-water bath to obtain catechin-loaded auricularia fuscosuccinea polysaccharide-gelatin nanocapsule suspension. The preparation method disclosed by the invention is simple and convenient, the process is safe and controllable, the physicochemical properties are synergistically exerted by taking the auricularia fuscosuccinea polysaccharide and the gelatin as the composite wall material, the efficient loading and slow release of the catechin are realized, and a new thought is provided for the application of the auricularia fuscosuccinea polysaccharide and the improvement of the bioavailability of the catechin.
Owner:BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES

Antioxidant and antibacterial collagen repair membrane

The invention discloses an antioxidant and antibacterial collagen repair membrane and a preparation method thereof. The repair membrane is prepared by sequentially carrying out polylysine graft modification and catechinic aldehyde and aminoglycoside antibiotic synchronous covalent grafting on a purified collagen membrane. By controlling parameters such as molecular weight and concentration of polylysine, proportion and loading capacity of functional molecules, reaction conditions and the like, accurate regulation and control of film thickness, function release rate, oxidation resistance and antibacterial performance can be realized. The invention further provides a double-layer composite membrane structure, the rapid antibacterial layer and the long-acting anti-oxidation layer are compounded, and function decoupling and time sequence collaboration are achieved. The repair membrane has excellent oxidation resistance and broad-spectrum antibacterial performance, is good in biocompatibility and adjustable in degradation rate, can be customized according to different clinical requirements, and is suitable for oral wound repair, periodontal guided tissue regeneration, bone tissue induced regeneration, peri-implantitis prevention and treatment and chronic refractory wound treatment.
Owner:SHANDONG BODA MEDICAL PROD CO LTD

Preparation method and application of grape seed extract

The invention belongs to the field of extraction, processing and application of natural plant products, and particularly relates to a preparation method of a grape seed extract and application of the grape seed extract in preparation of a composition for preventing hair loss and growing hair. Tests prove that the grape seed extract can remarkably promote proliferation of hair papilla cells, inhibit apoptosis of the hair papilla cells and remarkably promote expression of factors representing that hair papilla enters an active cycle, is beneficial to inducing or maintaining the growth period of hair follicles and achieving self-rebuilding of the hair follicles, has good effects of preventing hair loss and growing hair, and can be used for preventing hair loss. A new way is provided for development and utilization of the grape seed extract.
Owner:BY HEALTH CO LTD

Method for stabilizing wild cranberry anthocyanin by catechin

The invention discloses a method for stabilizing wild cranberry anthocyanin by catechin, and belongs to the field of functional food development. The operation process comprises the following steps: treating cranberries at-20 DEG C, cleaning, crushing, mixing with 75% ethanol, and carrying out centrifugal adsorption to obtain an extracting solution; preparing a standard solution by using 12% ethanol and 5.0 g / L citric acid, and adjusting the pH value of the standard solution to 3.6 by using 1 mol / L sodium hydroxide; and finally, adding the wild cranberry extracting solution and catechin into the standard solution according to the gradient molar ratio of (1: 0.5, 1: 1, 1: 1.5 and 1: 2), carrying out ultrasonic treatment at the temperature of 25 DEG C for 30 minutes at the power of 150w, and placing in a dark place for 2 hours. The above method is a method for stabilizing wild cranberry anthocyanin by catechin.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY