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105 results about "Catechin" patented technology

Catechin /ˈkætɪtʃɪn/ is a flavan-3-ol, a type of natural phenol and antioxidant. It is a plant secondary metabolite. It belongs to the group of flavan-3-ols (or simply flavanols), part of the chemical family of flavonoids.

Coated hydrophobic polyphenol nanoparticles, preparation method therefor and application thereof

The present invention discloses coated hydrophobic polyphenol nanoparticles, preparation method therefor and application thereof. The preparation method for coated hydrophobic polyphenol nanoparticles includes: (1) obtaining a hydrophobic polyphenol nanoparticles suspension; (2) injecting a catechin aqueous solution and a metal salt aqueous solution into the hydrophobic polyphenol nanoparticles suspension to obtain a composite nanoparticles suspension; (3) removing excess catechin and metal ions from the composite nanoparticles suspension to obtain a coated hydrophobic polyphenol nanoparticles suspension. The present invention provides an application of the coated hydrophobic polyphenol nanoparticles in the preparation of pectin gel. The coated hydrophobic polyphenol nanoparticles exhibit significantly enhanced biological activity and long-term stability, developing a pectin gel with long-term stability.
Owner:ZHEJIANG UNIV OF TECH

Multi-effect analgesic and anti-inflammatory gel for oral cavity and preparation method thereof

PendingCN121265525AOrganic active ingredientsPeptide/protein ingredientsDipotassium GlycyrrhizateQuercitrin
The invention discloses oral multi-effect analgesic and anti-inflammatory gel and a preparation method thereof, and belongs to the technical field of medical gel. The gel is prepared from mussel mucin grafted hydroxypropyl chitosan, a poly (N-isopropylacrylamide)-co-acrylic acid copolymer, quercetin-zinc coordination nanoparticles, a local anesthetic compound wrapped by temperature-sensitive lipidosome, a gamma-polyglutamic acid-catechin gel matrix, aloe polysaccharide, dipotassium glycyrrhizinate, and sodium hyaluronate and potassium sorbate which can be selectively added, wherein the local anesthetic compound is prepared from the mussel mucin grafted hydroxypropyl chitosan, the poly (N-isopropylacrylamide)-co-acrylic acid copolymer, the quercetin-zinc coordination nanoparticles, the temperature-sensitive lipidosome, the gamma-polyglutamic acid-catechin gel matrix, the aloe polysaccharide and the dipotassium glycyrrhizinate. During preparation, part of the components and water are stirred to obtain a mixed solution, and then the other components are added and stirred into gel. According to the gel, the leakage rate of local anesthetics is reduced by stabilizing the liposome through the zinc ions, the quercetin adjusts the phase transition temperature of the liposome to realize preferential drug release at the pain part, the mussel mucin and the copolymer form a reversible hydrogen bond network to enhance the mucous membrane adhesive force, and the inflammatory environment triggers the gel permeation drug release, so that the gel has the advantages of multiple-effect synergy, strong adhesion and the like; the problems that existing oral gel is short in analgesia time and insufficient in anti-inflammation can be effectively solved.
Owner:BEIJING STOMATOLOGY HOSPITAL CAPITAL MEDICAL UNIV

Fish and shellfish feed

To provide fish and shellfish feed, fish and shellfish feed additives, a method for producing fish and shellfish feed, and a method for raising fish and shellfish that can produce fish and shellfish in good health. [Solution] The following components (A) and (B): (A) Non-polymerized catechins 0.001-1.5% by mass (B) Oligosaccharides A fish and shellfish feed containing [this ingredient].
Owner:KAO CORP

A cleaning and passivation method for small-diameter grooved special-shaped copper wire

The present application belongs to the field of metal wire cleaning, and provides a cleaning and passivation method for special-shaped copper wire with grooves and small wire diameter; first, the copper wire is pre-blowed by an annular air knife to remove surface attachments, and is introduced into a groove guide water pipe; then, directional hot water consistent with the groove direction of the copper wire is used for strong flushing, and catechin gel mother liquor is added in the cleaning liquid and a brush is arranged for cooperative brushing; the copper wire is introduced into an ultrasonic cleaning tank for reciprocating deep purification, and the purified copper wire is introduced into a hot air duct arranged in the groove for deep dehydration and guide flow drying; the copper wire is introduced into a passivation chamber provided with an ultrasonic atomizer, and a passivation liquid containing a succinimidazole agent is atomized into uniform fine mist droplets to cover the copper wire; after the copper wire is finally dried by hot air, film formation and solidification are completed, and then the copper wire is wound, effectively solving the problems of difficult cleaning of special-shaped copper wire grooves and uneven passivation film, and improving the surface quality and oxidation resistance of the product.
Owner:浙江嘉杭机械科技有限公司

Characteristic chromatogram of platelet increasing capsule as well as construction method and application thereof

The invention discloses a platelet increasing capsule characteristic chromatogram and a construction method and application thereof, and belongs to the technical field of quality control of traditional Chinese medicine compound preparations. According to the method, 13 control components including gallic acid, catechin, paeoniflorin, forsythiaside B, benzoic acid, astragalus smicus glycoside, forsythin, arctiin, liquiritigenin, benzoyl paeoniflorin, paeonol, arctigenin and indirubin are selected, a high performance liquid chromatography-mass spectrometry technology is applied, multiple batches of preparation samples are analyzed, and the content of the components in the preparation samples is determined. And establishing a characteristic spectrum of the chemical components. Compared with a traditional method, the technology has good precision and reproducibility, the data result is accurate and reliable, meanwhile, the technology can identify the 13 components at the same time under the same chromatographic condition, the analysis efficiency is remarkably improved, synchronous monitoring of multiple effective components is achieved, and the consistency and stability of the preparation quality can be guaranteed.
Owner:SHAANXI UNIV OF SCI & TECH

Antioxidant and antibacterial collagen repair membrane

The invention discloses an antioxidant and antibacterial collagen repair membrane and a preparation method thereof. The repair membrane is prepared by sequentially carrying out polylysine graft modification and catechinic aldehyde and aminoglycoside antibiotic synchronous covalent grafting on a purified collagen membrane. By controlling parameters such as molecular weight and concentration of polylysine, proportion and loading capacity of functional molecules, reaction conditions and the like, accurate regulation and control of film thickness, function release rate, oxidation resistance and antibacterial performance can be realized. The invention further provides a double-layer composite membrane structure, the rapid antibacterial layer and the long-acting anti-oxidation layer are compounded, and function decoupling and time sequence collaboration are achieved. The repair membrane has excellent oxidation resistance and broad-spectrum antibacterial performance, is good in biocompatibility and adjustable in degradation rate, can be customized according to different clinical requirements, and is suitable for oral wound repair, periodontal guided tissue regeneration, bone tissue induced regeneration, peri-implantitis prevention and treatment and chronic refractory wound treatment.
Owner:SHANDONG BODA MEDICAL PROD CO LTD

Method for stabilizing wild cranberry anthocyanin by catechin

The invention discloses a method for stabilizing wild cranberry anthocyanin by catechin, and belongs to the field of functional food development. The operation process comprises the following steps: treating cranberries at-20 DEG C, cleaning, crushing, mixing with 75% ethanol, and carrying out centrifugal adsorption to obtain an extracting solution; preparing a standard solution by using 12% ethanol and 5.0 g / L citric acid, and adjusting the pH value of the standard solution to 3.6 by using 1 mol / L sodium hydroxide; and finally, adding the wild cranberry extracting solution and catechin into the standard solution according to the gradient molar ratio of (1: 0.5, 1: 1, 1: 1.5 and 1: 2), carrying out ultrasonic treatment at the temperature of 25 DEG C for 30 minutes at the power of 150w, and placing in a dark place for 2 hours. The above method is a method for stabilizing wild cranberry anthocyanin by catechin.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

A senescent cell mitochondria-targeting nanodelivery material and its application in anti-aging

This invention discloses a mitochondrial-targeted nanomaterial for senescent cells and its application in anti-aging. The material is a nucleic acid aptamer-tetrahedral DNA, mainly assembled from four single-stranded DNA sequences, SEQ ID Nos. 1-4. Preparation involves first hybridizing the four single-stranded DNA sequences, then concentrating them to obtain aptamer-modified tetrahedra, which are then coupled with tannic acid (TA) via a Mann reaction in the presence of formaldehyde to obtain the Apt-tFNAs-TA complex. Finally, it is incubated with excess catechins to obtain the final delivery material, Apt-tFNAs@catechin-TA. This invention's material exhibits good biocompatibility and skin tissue compatibility, significantly improving uptake efficiency and mitochondrial localization ability in senescent cells. It can effectively deliver polyphenolic compounds such as catechins and protocatechuic acid, improving mitochondrial function and addressing the technical problems of low delivery efficiency of active ingredients and insufficient targeted enrichment in senescent cells.
Owner:ZHEJIANG UNIV

Silver catechin nano antibacterial particles as well as preparation method and application thereof

The invention discloses a catechin silver nano antibacterial particle as well as a preparation method and application thereof, and belongs to the technical field of antibacterial materials. The silver catechin nano antibacterial particles disclosed by the invention are Ct-Ag NPs, and the silver catechin nano antibacterial particles are Ct-Ag NPs; the Ct-Ag NPs is of a spherical structure; the average particle size of the Ct-Ag NPs ranges from 142 nm to 162 nm; ag in the Ct-Ag NPs is uniformly dispersed in catechin to form a core-shell structure. The preparation method of the silver catechin nano antibacterial particles comprises the following steps: weighing catechin, and dissolving the catechin in a sodium hydroxide solution to obtain a catechin sodium salt solution; adding the silver nitrate solution into the ammonia water solution to obtain a silver ammonia solution; and under the conditions of stirring and ice bath, adding the catechin sodium salt solution into the silver ammonia solution, centrifuging, cleaning with trichloromethane, and drying to obtain the Ct-Ag NPs. The Ct-Ag NPs provided by the invention has a core-shell structure, and the quorum sensing inhibitor shell Ct can effectively reduce the generation of biological membranes, so that bacteria are more sensitive, and the bactericidal effect of continuously releasing Ag < + > is effectively improved.
Owner:ACADEMY OF MILITARY MEDICAL SCIENCES

Environment-adaptive high-energy-absorbing intelligent anticorrosive coating and preparation method thereof

This invention discloses an environmentally adaptive high-energy-absorbing smart anti-corrosion coating and its preparation method, comprising: synthesizing a dipyrazole diamine chain extender, formulating a long-chain polymer backbone A and a catechol-terminated short-chain polymer B, and preparing a high-energy-absorbing smart anti-corrosion coating; the coating utilizes the interaction between dipyrazole and Zn in the long chain. 2+ Multiple coordination reduces the entropy increase effect of bond breaking and enhances energy dissipation; gradient hierarchical hydrogen bonds between long and short chains, in coordination with metal coordination bonds, act as sacrificial bonds to dissipate energy through stepwise breakage under external force; the slightly alkaline nature of seawater triggers deprotonation of catechols and reconstructs the coordination network, increasing crosslinking density and enhancing shielding; and the Fe released at the breakage site... 3+ By strongly coordinating with catechins to form a passivation layer in situ, and using its photothermal effect to drive the self-repair of the substrate, this invention solves the problem of the difficulty in simultaneously achieving high energy absorption, fatigue resistance, environmental response, efficient self-repair and intelligent corrosion prevention in offshore wind turbine tower coatings, which helps to extend the service life of wind turbine towers and ensure the reliability of the units.
Owner:XIAN UNIV OF TECH

A method for determining the content of gallic acid and (+)-catechin in sesame medicinal material.

This invention discloses a method for determining the content of gallic acid and (+)-catechin in *Hedysarum heterotropoides* medicinal materials. After reflux treatment with 60% methanol solution in a water bath, the *Hedysarum heterotropoides* medicinal materials are subjected to high-performance liquid chromatography (HPLC) with octadecyl-bonded silica gel as the stationary phase and acetonitrile (A)-0.1% phosphoric acid aqueous solution (B) as the mobile phase. The peak area values ​​of gallic acid and (+)-catechin showed good linearity in the injection amounts of 10.00–100.0 μg and 200.0–2000 μg, respectively, with average recoveries of 98.31% and 97.68%, and RSD values ​​of 1.2% and 1.2%, respectively. The method is simple and accurate, and can be used for the determination of gallic acid and (+)-catechin content, providing a theoretical basis for the quality control of *Hedysarum heterotropoides* medicinal materials.
Owner:QIANXINAN PREFECTURE HOSPITAL OF TRADITIONAL CHINESE MEDICINE

A food composition having antioxidant and procollagen synthesis promoting effects and a method for preparing the same

PendingCN122320230ABiotechnologyAntioxidant
This invention discloses a food composition with antioxidant and collagen synthesis-promoting effects and its preparation method, relating to the field of food technology. The food composition comprises the following ingredients in parts by weight: 300-500 mg collagen, 100-400 mg astragalus polysaccharide, 100-400 mg grape seed proanthocyanidins, 10-200 mg catechins, 5-100 mg ergothioneine, and 5-50 mg soybean oligopeptides. This food composition can increase the collagen content in the skin, enhance facial skin elasticity, reduce transepidermal water loss, and improve skin aging-related conditions. This invention constructs a dual-core synergistic formula of "antioxidant + collagen synthesis promotion" through the scientific formulation of seven active ingredients. All components of this invention use food-grade raw materials, making the formula mild and safe; all ingredients are natural extracts or edible raw materials, ensuring high safety, no obvious toxic side effects, and long-term daily use, making it suitable for a wide range of people.
Owner:SHANGHAI LANGSI ZHIYAO BIOTECHNOLOGY DEVELOPMENT CO LTD

A water-washable anti-deformation fabric and a preparation method thereof

The application discloses a kind of washable anti-deformation fabric and preparation method thereof, it is related to fabric technical field.The application uses natural antibacterial agent to carry out co-modification to cellulose fiber, natural antibacterial agent is composed of catechin, citric acid, amino acid, natural antibacterial agent utilizes its amino, carboxyl, hydroxyl, and the hydroxyl of cellulose fiber reacts, forms crosslinking structure, improves the wet strength and dimensional stability of cellulose fiber, further enhances the binding force between fibers, reduces the swelling and shrinkage of fiber in the washing process.Meanwhile, silver molybdate loaded sepiolite and finishing agent form a dense protective film on the surface of the fabric, prevent the penetration of water molecules and the adhesion of bacteria, further improve the washability and antibacterial property of the fabric.
Owner:NINGBO NIKAI CLOTHING CO LTD

A biodegradable material, its preparation method and its application

ActiveCN120737565Bgood adhesionpromote reproductionPolymer scienceBackbone chain
This invention relates to the field of polymer degradable materials technology, specifically to a biodegradable material, its preparation method, and its applications. The material is based on modified polylactic acid (PLA), supplemented by antioxidants, plasticizers, flame retardants, and inorganic fillers in specific weight proportions. Its unique feature lies in the polymerization of lactic acid and epicatechin imidazole ammonium chloride polymer under stannous octoate catalysis, using chemical bonding to introduce the bioactive groups of epicatechin into the PLA backbone, significantly improving the material's biodegradation rate, mechanical properties, and thermal stability. The bioactive substances and ionic groups in this material promote microbial degradation, achieving complete decomposition in a composting environment within a short time. Simultaneously, through molecular-level reinforcement and ionic cross-linking effects, the strength, toughness, and high-temperature processing performance of PLA are effectively improved. This material can be widely used in disposable tableware, food packaging films, and biodegradable agricultural mulch films.
Owner:HUNAN GREEN STAR NEW MATERIALS CO LTD

Composition for amelioration, prevention or treatment of hair loss, comprising catechin 7-o-beta-d-apiofuranoside as active ingredient

The present invention relates to a composition for ameliorating, preventing or treating alopecia, comprising a catechin 7-O-β-D-apiofuranoside compound as an active ingredient. The compound of the present invention inhibits the production of dihydrotestosterone (DHT) converted from testosterone by 5-alpha-reductase in human-derived dermal papilla cells, and inhibits the apoptosis induced by oxidative stress in dermal papilla cells, and accordingly, can be used as an active ingredient for the treatment, prevention, or amelioration purposes.
Owner:ANPOLY INC

Preparation and application of bone targeting catechin-strontium metal polyphenol nanoparticles

PendingCN121891548AAchieve synchronous deliveryImplement sequential releaseSkeletal disorderPharmaceutical non-active ingredientsBone regenerationBone quality
The invention discloses a preparation method and an application of a bone targeting catechin-strontium metal polyphenol nano particle. The system takes a metal-polyphenol network (MPN) formed by coordination self-assembly of strontium ions and catechin as a core, and tetracycline is modified on the surface of the MPN to construct a bone targeting functional layer. The MPN structure can significantly enhance the loading efficiency and physiological stability of catechin, and the tetracycline modification on the surface endows the nanoparticles with excellent bone targeting ability. When reaching an osteoporosis focus, the nanoparticles can respond to a local weakly acidic microenvironment and controllably release catechin, and exert antioxidant and anti-inflammatory effects, thereby reversing a pathological microenvironment unfavorable for bone regeneration. Meanwhile, the MPN skeleton is gradually degraded in vivo, and the released Sr < 2 + > can promote proliferation and differentiation of pre-osteogenic cells, inhibit the activity of osteoclasts and promote formation of new bones. The system integrates bone targeting, microenvironment response drug release, immunoregulation and ion regulation treatment, and provides a new strategy for precise treatment of osteoporosis.
Owner:GUANGDONG NO 2 PROVINCIAL PEOPLES HOSPITAL +1

Two-component reactive odor removing agent for road asphalt as well as preparation method and application of two-component reactive odor removing agent

The invention discloses a two-component reactive odor removing agent for road asphalt as well as a preparation method and application of the two-component reactive odor removing agent. The odor removing agent is prepared from a component A and a component B according to a mass ratio of 1: (1.5-4), the additive is prepared from sodium lignin sulfonate, calcium lignin sulfonate, rosin modified phenolic resin, lignin sodium sulfate, lignin calcium sulfate, quercetin, catechin or gallic acid. The component B comprises 1-5 parts of vanillin, 30-46 parts of nano zinc oxide, 4-6 parts of anhydrous cupric sulfate, 4-8 parts of zinc stearate, 1-4 parts of anhydrous magnesium sulfate, 5-7 parts of activated carbon and 4-8 parts of dioctyl phthalate. In the asphalt smoke release process, the odor removing agent can generate different physical and chemical effects with asphalt molecules in different stages, so that synergistic odor reduction and smoke suppression among the materials are realized. Due to the low mixing amount of the odor removing agent, the good using performance of the odor removing asphalt is guaranteed, and the short-term aging resistance of the odor removing asphalt can be improved.
Owner:XI'AN UNIVERSITY OF ARCHITECTURE AND TECHNOLOGY

Nanoparticles for improving stability of catechin and preparation method thereof

The invention discloses a nano-particle for improving stability of catechin and a preparation method thereof, the nano-particle comprises catechin, lactoprotein, chitosan and sodium tripolyphosphate according to a weight ratio, the catechin nano-particle is constructed by adopting a self-assembly strategy, the preparation process is simple and convenient, and the conditions are mild. The raw materials are all safe and reliable food-grade or edible components which are wide in source and sufficient in supply, and the method has good amplification performance and industrial application prospects. The encapsulation efficiency is 90% or above, active ingredients can be effectively embedded and protected, the stability of catechin under various complex or extreme environment conditions such as high temperature, illumination and alkalinity is remarkably improved, the stability under the extremely high temperature condition is improved by 10 times or above, and the stability under the alkaline condition is improved by 12 times or above; the technical problem that catechin is easy to degrade and inactivate in the processing and storage process is fundamentally solved. The catechin can better adapt to food processing, health care product production and related application scenes, the practical application range of the catechin is greatly widened, and the added value of the product is improved.
Owner:CHINA JILIANG UNIV

Method for extracting rubusoside from Jinxiu sweet tea and preparing highly concentrated syrup

The invention relates to a method for extracting rubusoside from Jinxiu sweet tea and preparing high-concentration syrup, and belongs to the technical field of natural product extraction and food processing.The method comprises the steps that after raw materials are subjected to explosion-proof smashing, a refined solution is obtained through countercurrent extraction and membrane filtration; enriching rubusoside by adopting a series adsorption-parallel analysis chromatography process, and then debitterizing by using obligate resin; and finally, preparing high-purity syrup at low temperature and vacuum through a double-effect flash evaporation concentration system, and integrating ethanol condensation, recovery and cyclic utilization. The device realizes continuous and explosion-proof production, and has the characteristics of high extraction efficiency, high product purity, low energy consumption, recyclable solvent and safe and controllable production process.
Owner:DARK HORSE DANGSHENG (JINXIU) GREEN AGRICULTURAL TECHNOLOGY CO LTD

An amino acid cleansing composition having high thermal stability and a method of preparing the same

The present application provides an amino acid cleansing composition with high thermal stability and a preparation method thereof, and belongs to the field of medical, dental or cosmetic preparations. The composition is composed of an amino acid surfactant, an amphoteric surfactant, a silanized cross-linked modified starch, a fatty acylated plant protein derivative, a catechin or derivative thereof, and a structure inducing lipid. The present application builds a dynamic ordered structure network in the system by the synergistic effect among the silanized cross-linked modified starch, the fatty acylated plant protein derivative, the catechin or derivative thereof, and the structure inducing lipid, thereby significantly improving the thermal stability, structure maintaining ability and high and low temperature rheological stability of the amino acid cleansing system, and improving the paste standing ability, pearl luster uniformity, push spreading feeling and foam fineness.

Multifunctional pharmaceutical composition for comprehensive tooth repair and preparation method thereof

The present application relates to a kind of multifunctional pharmaceutical composition of dental comprehensive repair and its preparation method, belong to biopharmaceutical technical field, and pharmaceutical composition includes keratin peptide, coral fungus extract, eggshell derived nano calcium phosphate, catechin zinc complex, hydroxyapatite, modified chitosan-PEG gel and other components.Keratin peptide is the product between 3kDa-10kDa obtained by keratinase enzymolysis to white goose velvet;Coral fungus extract is the product obtained by cellulase, subtilisin and bromelain enzymolysis to coral fungus, and purified by G-25 dextran gel column;Modified chitosan-PEG gel is the product obtained by sodium cyanoborohydride stabilization and glycerol plasticization to the reactant of chitosan and dialdehyde polyethylene glycol.Integrated multiple functions such as antibacterial, mineralization and tissue repair, through optimizing component and dosage form, realize efficient, minimally invasive dental damage repair, and good biocompatibility and long-acting.
Owner:HUBEI SHUANGXING PHARMA CO LTD

Method for reducing cutaneous skin scarring by pre-emptive priming and compounds and compositions for its implementation

ActiveUS12691092B2SKIN SCARRINGGallagic acid
A method of enhancing the quality of a skin scar by topical application of an agent for improving scar quality is characterised in that said agent is pre-emptively applied to a potential surgical cutaneous site in advance of surgery, including surgery involving use of lasers. The topical agent may be a polyphenol, such as (-)-epigallocatechin-3-gallate (EGCG). Use of such a topical agent in advance of surgery leads to significant beneficial effects on dermal scarring by reducing mast cells, angiogenesis, skin thickness and simultaneously increasing elastin content. The topical agent may be applied directly or incorporated in a dressing, such as in a dermal patch comprising an adhesive silicone sheet, and can be worn both in the lead up to surgery and post-operatively.
Owner:SOS SCIENCE OF SKIN LTD

Method for detecting content of components in rhodiola rosea medicinal material or preparation and application

The invention relates to the technical field of traditional Chinese medicine analysis methods, in particular to a method for detecting the content of components in a rhodiola quadrifida medicinal material or preparation and application of the rhodiola quadrifida medicinal material or preparation. The invention discloses a method for detecting the content of components in a rhodiola rosea medicinal material or preparation. The method comprises the following steps: detecting a test solution of the rhodiola rosea medicinal material or preparation by adopting ultra-high performance liquid chromatography; target components detected in the detection method comprise phenolic acid components and / or phenolic glycoside components and / or catechin components. The detection conditions of the ultra-high performance liquid chromatography are as follows: a formic acid methanol solution is used as a mobile phase A, a formic acid aqueous solution is used as a mobile phase B, and gradient elution is performed. The detection method disclosed by the invention can be used for simultaneously detecting phenolic acid, phenolic glycoside and catechin components in the rhodiola quadrifida, the quality control components are more comprehensive, and the method is simple, convenient, feasible, high in sensitivity, strong in specificity and good in durability.
Owner:NORTHWEST INST OF PLATEAU BIOLOGY CHINESE ACAD OF SCI

Nano-particles for resisting saccharification and aging, preparation method of nano-particles and composition for resisting saccharification and aging

The invention relates to the technical field of anti-saccharification and anti-aging, in particular to anti-saccharification and anti-aging nanoparticles, a preparation method of the anti-saccharification and anti-aging nanoparticles and an anti-saccharification and anti-aging composition. The preparation method comprises the following steps: under the protection of inert gas, hyaluronic acid and L-carnosine are subjected to an acid-amine condensation reaction under the catalytic action of a carboxyl activator to obtain a hyaluronic acid-carnosine derivative; and performing a coordination self-assembly reaction on the digallocatechin a, Zn < 2 + > and the hyaluronic acid-carnosine derivative in deionized water to form the nanoparticles as shown in a formula II. In the nano-particle structure, the HA-CAN component mainly aims at an AGEs / RAGE pathway; the TSA-Zn component mainly aims at an HMGB1 / RAGE pathway, and the TSA-Zn component and the HMGB1 / RAGE pathway cooperatively inhibit dual pathways; the introduction of HA greatly improves the transdermal performance, CAN, TSA and HA are integrated in a nano entity through chemical bonds / coordinate bonds, the stability of the nano structure is improved, and the activity of each component is enhanced.
Owner:SHANGHAI CHEERMORE IND DEV CO LTD

Diphenylethylene compounds and compositions thereof

The present application relates to the use of a diphenylethylene compound or a pharmaceutically acceptable salt, prodrug and / or solvate thereof and / or pterostilbene or a pharmaceutically acceptable salt, prodrug and / or solvate thereof, and to a composition, the composition comprises the diphenylethylene compound or a pharmaceutically acceptable salt, a prodrug and / or a solvate of the diphenylethylene compound and / or the pterostilbene or a pharmaceutically acceptable salt of the pterostilbene. The prodrugs and / or solvates and further in combination with curcumine and catechins to treat papillomavirus infections and diseases, disorders or conditions caused by papillomavirus infections, such as cancer.
Owner:INNOVIN CO LTD +1

Preparation method of cellular pathway activation composition for tightening and lifting skin

The invention relates to the technical field of plant extracts, and particularly discloses a preparation method of a cell pathway activation composition for tightening and lifting skin, which comprises the following steps: preparing a water-phase gel matrix and an oil phase, and then mixing to obtain massage cream with a lamellar liquid crystal gel structure. High-efficiency permeation is realized by virtue of certain similarity with a skin cuticle intercellular lipid structure; meanwhile, various plant extracts are adopted in the formula of the composition, the problem that nutrient substance transportation of facial skin is not smooth due to low cell pathway efficiency is solved by regulating and controlling the cell pathway, and the skin loosing and droop can be relieved in time; meanwhile, the skin elasticity is improved for a long time by stimulating fibroblast proliferation and promoting collagen synthesis; in addition, the composition adopts a protective agent integrating three functions of oxidation resistance of catechin, chelation of phytic acid and physical barrier of a polymer skeleton, so that the protectiveness of plant extracts is improved.
Owner:QINGHE YUNSHENG BIOTECHNOLOGY (WUXI) CO LTD

Food-grade antibacterial acrylic resin packaging material and preparation method thereof

The invention belongs to the field of functional packaging materials, and discloses a food-grade antibacterial acrylic resin packaging material and a preparation method thereof.The food-grade antibacterial acrylic resin packaging material is based on a water-based emulsion free of volatile organic compounds, a stable dispersion system is constructed through a co-emulsion and a wetting agent, and the functional packaging material is prepared. A natural catechin polymer subjected to acrylation modification is covalently anchored to an acrylic matrix, and a natural vitamin E derivative and a metal oxide nanosheet are compounded, so that multiple functions of antibiosis, antioxidation and gas barrier are integrated. The preparation method combines emulsion polymerization with an ultraviolet light and microwave dual-curing technology, and is mild and efficient in process and free of harmful emission. The obtained coating has lasting antibacterial property, stable antioxidant property and excellent barrier property, meets the food contact safety standard, is suitable for various food packaging scenes, and has remarkable application value and industrialization prospect.
Owner:唐维康(上海)食品科技有限公司

Emulsion for improving memory activity of DHA (docosahexaenoic acid) as well as preparation method and application of emulsion

PendingCN121986924AStable protection and targeted deliveryeffective protectionOrganic active ingredientsNervous disorderPhospholipinPhospholipid complex
The invention relates to the technical field of biological substance preparation. The invention provides a catechin-phospholipid complex and an emulsion prepared from the catechin-phospholipid complex and capable of improving DHA (docosahexaenoic acid) and improving memory activity. The invention also provides an application of the catechin-phospholipid complex or the emulsion for improving the memory activity of DHA in preparation of health-care products. The emulsion prepared by adopting the catechin-phospholipid compound as an emulsifier can efficiently and synergistically entrap, stably protect and deliver the beta-carotene and the DHA in a targeted manner, so that the bioavailability and the multi-component synergistic effect of the beta-carotene and the DHA are enhanced, and the effect of improving the memory function is realized; meanwhile, good physical and chemical stability and digestion tolerance are also shown.
Owner:BOHAI UNIV

Attapulgite / calcium silicate composite material and application thereof in acidic soil remediation

The application discloses a palygorskite / calcium silicate composite material. The palygorskite / calcium silicate composite material is composed of calcium silicate and modified palygorskite, wherein the modified palygorskite is palygorskite modified by succinic acid and catechin, and the modified palygorskite is loaded on the surface of the calcium silicate. Compared with the prior art, the application combines the modified palygorskite and the calcium silicate to form a synergistic effect, so that the acid soil can be repaired efficiently, economically and sustainably.
Owner:NORTHWEST NORMAL UNIVERSITY +2

Method for rapidly determining various phenolic acid substances in fermentation product

PendingCN122017093AComponent separationVolatile phenolsChlorogenic acid
The invention discloses a method for rapidly determining various phenolic acid substances in a fermentation product, and belongs to the technical field of detection. The determination method comprises the following steps: 1. Taking a to-be-detected substance, and extracting phenolic acid substances in the to-be-detected substance through an alcohol precipitation-SAX solid-phase extraction combined technology to obtain a to-be-detected sample; analyzing the to-be-detected sample by adopting ultra-high performance liquid chromatography tandem triple quadrupole mass spectrometry to obtain the content of the target substance in the to-be-detected substance; the target substance is a non-volatile phenolic acid substance. Accurate quantification of trace and trace caffeic acid, dihydrocaffeic acid, ferulic acid, chlorogenic acid, gallic acid, vanillic acid, syringic acid, p-coumaric acid, salicylic acid and (+ / -)-catechin in fermentation products within 8-15 min is achieved by combining impurity removal and concentration pretreatment with ultra-high performance liquid chromatography tandem triple quadrupole mass spectrometry. According to the method, the pretreatment mode is convenient to operate, the detection process is fast, and the detection result is accurate.
Owner:ANHUI GUJING DISTILLERY CO LTD