The invention discloses a traditional Chinese medicine composition for treating common cold and upper respiratory tract infection. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10 to 80 parts of raw gypsum, 5 to 50 parts of forsythia suspensa, 5 to 50 parts of radix isatidis, 5 to 40 parts of fineleaf schizonepeta herb, 5 to 40 parts of fermented soybeans, 5 to 45 parts of perilla leaves, 5 to 45 parts of semen perillae acutae and 2 to 30 parts of licorice. Original efficacy of each raw material is played, and meanwhile, the raw materials interact and coordinate to achieve the effects of clearing heat, removing toxicity, relieving exterior syndromes, dispelling cold, clearing and diffusing lung heat, expelling phlegm to arrest coughing, cooling blood, relieving sore throat, and killing and inhibiting bacteria; the formula is rigorous, and the raw materials are scientifically combined, blended and supplement one another to achieve the effect of unified treatment over various types of exterior and interior cold, heat and summer damp; the root of each type of common cold is seized, disease differentiation is combined with syndrome differentiation, and the raw materials can be dialectically applied to treat various types of common cold and upper respiratory tract infection. A reproductive toxicity efficacy experiment on the traditional Chinese medicine composition formed by the raw materials shows that the traditional Chinese medicine composition is free of remarkable influence on a pregnant rat and a fetal rat, and can be applied to the treatment of common cold of pregnant women and infants.