198 results about "Anisole" patented technology

The invention provides a biosynthesis inhibitor of migratory locust aggregation pheromone 4-vinyl anisole and application of the biosynthesis inhibitor. The biosynthesis inhibitor of migratory locust aggregation pheromone 4-vinylanisole reduces the activity of 4-vinylphenol methyltransferase, and the 4-vinylphenol methyltransferase contains an amino acid sequence selected from the following sequences: (a) a sequence as shown in any one of SEQ ID No.1 and SEQ ID No.3; and (b) a sequence which is obtained by deleting, inserting and / or substituting one or more amino acid residues in the sequence shown in any one of SEQ ID No.1 and SEQ ID No.3 and has the activity of catalyzing generation of migratory locust aggregation pheromone 4-vinyl anisole. The inhibitor can be applied to biological prevention and control of migratory locusts, can keep locusts in a harmless scattered state instead of killing the locusts, provides a new method for biological prevention and control of migratory locusts, and has a wide application prospect.

The invention relates to a method for directly preparing (methyl) anisole from phenol and methanol, which comprises the following steps: under the action of a composite catalyst, phenol and methanol are catalyzed to generate methyl anisole, and the composite catalyst is prepared by mixing a Ho / beta molecular sieve catalyst and Ti / UiO-66 according to a mass ratio of Ho / beta: Ti / UiO-66 of 0.3-0.6: 1. According to the process, the reaction steps are simple, synthesis is achieved through one step, the total selectivity of methyl anisole reaches 76% or above, and continuous and stable operation can be conducted for 3000 h.

The utility model discloses equipment for removing anisole from circulating methanol, which comprises a tank body and a mixer, a plurality of baffle plates are sequentially arranged in the tank body from the mixer end to the other end, the baffle plates have three types, the left side of the baffle plate I is provided with a notch, the right side of the baffle plate II is provided with a notch, and the upper part of the baffle plate III is provided with a notch; the first baffle and the second baffle are distributed at intervals, and the third baffle is arranged at the last. The equipment disclosed by the utility model is simple in structure, easy to operate, good in removal effect of anisole in circulating methanol, friendly in production environment and low in production cost.

The invention provides a high-quality boron isotope separation process and device, the device comprises an exchange rectification system, a complexing system, a complex cracking system and a boron-11 refining system, natural abundance boron trifluoride isotopes are separated through an exchange rectification tower, and cyclic regeneration of boron trifluoride and anisole is realized by adopting the complexing system and the cracking system. A boron-11 refining system is arranged to further improve the abundance of boron-11. According to the method, the industrial continuous production of the high-quality boron trifluoride-10 with the abundance of 99% and the high-quality boron trifluoride-11 with the abundance of 99.9% can be synchronously realized, the process is simple and clear, and the operability is high.

The invention relates to the technical field of synthesis of organic compounds, and discloses a synthesis method of an o-aminoanisole compound, which comprises the following steps: preparing a composite alkali slow-release system consisting of inorganic alkali and organic alkali; preparing a catalytic reduction reaction system containing a metal complex stabilizer, a transition metal catalyst and a hydrophilic ether cosolvent; a catalytic reduction reaction of o-nitroanisole is carried out, and the slow-release alkali-coated material gradually releases the composite alkali to maintain a stable pH environment; after the reaction is completed, adding a packing material rapid digesting agent to remove a packing material structure, and meanwhile, rapidly separating and protecting a product by using a product protective extracting agent and an antioxidant synergistic protective agent; and purifying and recovering the final product to obtain a high-purity o-aminoanisole product. The reaction efficiency, the product purity, the service life of the catalyst and the separation efficiency are comprehensively improved through the synergistic effect of the eight components, the product purity reaches 99.5% or above, the catalyst can be recycled for 5-8 batches, and the separation time is shortened to 0.5-1 hour.

The invention discloses a method for synthesizing p-hydroxyanisole by catalyzing oxidation of anisole with a TS-1 titanium silicalite molecular sieve, which comprises the following steps: 1) adding anisole, acetonitrile, tert-butyl alcohol and the TS-1 titanium silicalite molecular sieve into a reaction container, controlling the temperature at 45-55 DEG C, and stirring for reaction; 2) filtering the TS-1 titanium silicalite molecular sieve; controlling the temperature to be 0-10 DEG C, and adding a reducing agent to quench oxidability; concentrating dry tert-butyl alcohol and acetonitrile; extracting by using an organic solvent; washing is performed; concentrating the dry organic phase; and 3) carrying out vacuum reduced pressure distillation, and collecting fractions to obtain the product. According to the method, the anisole which is relatively low in price is used as a raw material, the TS-1 titanium silicalite molecular sieve catalyst is used as a core, so that no black oil exists in the reaction for producing the p-hydroxyanisole, the yield of the p-hydroxyanisole is increased to 93% and the selectivity is as high as 97% due to the acetonitrile and tert-butyl alcohol solvents, the selectivity and conversion rate of the reaction are greatly improved, and the method is suitable for industrial production. The method has the characteristics of simple process, high yield, good quality and the like.

The invention discloses a solvent-removing lossless precise transfer method for a two-dimensional material. The method comprises the following steps: carrying out surface functionalization on a silicon wafer by using HMDS (hexamethyldisilazane); carrying out spin coating on the functionalized silicon wafer by adopting a PMMA anisole solution, and drying to form a PMMA supporting film; picking up the PMMA support film by using a heat release adhesive PDMS; pDMS / PMMA is transferred to the surface of a two-dimensional material / first substrate needing to be transferred, PDMS and PMMA are separated after heating, and PMMA covers the surface of the two-dimensional material; the PMMA / two-dimensional material is separated from the first substrate through etching of the etching solution; fishing up the PMMA / two-dimensional material separated from the first substrate by using PDMS; transferring the PMMA / two-dimensional material to a second substrate; and washing away PMMA with acetone, and blow-drying with nitrogen to obtain the product. The two-dimensional material can be cleanly, efficiently and accurately transferred, and the intolerance of the two-dimensional material to an organic solvent and the pollution of the organic solvent can be avoided.

The present invention relates to a process for the preparation of a compound of formula (I), a stereoisomer, a salt, a hydrate or a solvate thereof, (II) comprising the step of sulfinylation of a compound of formula (IV) to produce compound of formula (II); (IV) wherein: R1 and R2 are as defined in the claims, wherein said sulfinylation step is performed in the presence of a solvent selected from the group comprising benzene, toluene, ethylbenzene, xylene, chlorobenzene, bromobenzene, fluorobenzene, anisole, nitrobenzene, tetralin, dichlorobenzene, trimethylbenzene, ethylacetate, propylacetate, butylacetate, propanol, butanol, 2- methyltetrahydrofuran, diethylether, methyltertbutylether, cyclopentyl methyl ether, dichloromethane, tetrachloromethane, pentane, hexane, heptane, cyclohexane, decaline and mixtures thereof.

The present application relates to the technical field of pharmaceutical chemistry, and particularly relates to a preparation method of fenofibrate and impurities thereof. The present application carries out Friedel-Crafts acylation reaction on 4-chlorobenzoyl chloride, anisole, Lewis acid and benzene solvent, then carries out demethylation reaction, and then separates and purifies to obtain compound II, impurity compound IV and impurity compound V; the compound II (or impurity compound IV), 2-bromoisobutyric acid isopropyl ester, an alkaline reagent and an alcohol solvent are mixed to carry out etherification reaction, and then separated and purified to obtain fenofibrate (or impurity compound VI). The preparation method provided by the present application has high yield and high purity of fenofibrate, can realize identification of impurities in the preparation process of fenofibrate, and provides a convenient condition for quality control of bulk drug. Moreover, the raw materials and solvents used are widely sourced, low in cost and small in danger, the preparation method is high in safety factor, simple in operation, and suitable for large-scale industrial production.

The invention discloses a method for preparing three-dimensional graphene foam from organic silicon waste liquid, the three-dimensional graphene foam and application, and the preparation method comprises the following steps: (1) preheating and evaporating the organic silicon waste liquid to obtain organic silicon waste liquid steam, and mixing the organic silicon waste liquid steam with water vapor to obtain organic silicon waste liquid steam; then hydrolyzing in an inert atmosphere with a carrier gas flow rate of 100-1000 sccm, cooling, filtering to obtain synthesis gas, and passing the synthesis gas through an alkaline substance to obtain purified synthesis gas; (2) introducing the purified synthesis gas into a reaction furnace, carrying out a chemical vapor deposition reaction by taking foamed nickel as a substrate to obtain a three-dimensional graphene foam initial product and hydrogen-rich synthesis gas, and then preparing the hydrogen-rich synthesis gas on the surface of the three-dimensional graphene foam initial product according to the dosage per unit area of 0.2-1.0 mL / cm < 2 >, an anisole solution proppant of polymethyl methacrylate with the mass content of 5%-10% is coated, and then the three-dimensional graphene foam is obtained through acid etching. The three-dimensional graphene foam prepared by the method has excellent conductivity, is suitable for the field of functional materials such as electromagnetic shielding materials, and has a good industrial application prospect.

The present application relates to a kind of phenol and methanol directly prepared (methyl) anisole mode, the method includes the following steps: under the action of composite catalyst, phenol and methanol are catalytically generated methyl anisole, the composite catalyst is Ho / β molecular sieve catalyst and Ti / UiO-66 with mass ratio Ho / β:Ti / UiO-66 0.3-0.6:1 Mixed composite catalyst.The process reaction step is simple, and synthesis is realized in one step, and the total selectivity of methyl anisole is as high as 76% or more, and can be continuously and stably operated for 3000h.

It has been found that, by linking an N-terminal amino acid residue of a peptide compound with a C-terminal amino acid residue of the peptide compound in which at least one of the N-terminal amino acid residue and the C-terminal amino acid residue is a cyclic amino acid residue in a solvent containing one or more selected from the group consisting of acetonitrile, dimethyl carbonate, 2-MeTHF and anisole, epimerization can be suppressed and formation of oligomers can be reduced, thereby a cyclic peptide compound of interest can be efficiently produced.

The invention discloses a method for preparing anisole by taking dimethyl carbonate as a methylation reagent, a ternary concerted catalytic system is created for the first time to break through temperature limitation, phenol is efficiently activated by [BMIM] OH to generate high-activity phenoxy anions through a composite catalytic design of an alkaline ionic liquid / quaternary ammonium salt / nano metal oxide, the quaternary ammonium salt executes phase transfer and reaction path switching, and the anisole is prepared by taking dimethyl carbonate as a methylation reagent. The nano metal oxide has the effects of balance regulation and structural protection, and the conversion rate of phenol is gt according to the mass ratio of phenol to dimethyl carbonate to basic ionic liquid to quaternary ammonium salt compound to nano metal oxide being 94: (99-117): (2.82-7.52): (0.94-4.7): (0.47-3.76); the selectivity of anisole is gt; the method has the advantages that the concentration is 99%, decomposition of DMC and generation of by-products such as o-cresol are inhibited from the source, a self-settling separation-circulation method subverts a catalyst recovery mode, the by-products are directionally inhibited, the separation process is simplified, and the product can reach gt through single washing and reduced pressure distillation; and high-energy-consumption multi-tower rectification for substances with approximate boiling points in the traditional method is omitted, so that the economic benefit is greatly improved.

The invention discloses a UV (ultraviolet)-heat dual-curing waterborne polyurethane emulsion and a preparation method thereof. According to the UV-thermal dual-curing waterborne polyurethane emulsion, the heat resistance, the water resistance and the mechanical property of UV-WPUA can be improved, and meanwhile, the storage stability and the yellowing problem of the UV-WPUA can be improved; the polyurethane foam is prepared from the following components in parts by weight: 60-70 parts of binary isocyanate; 35 to 45 parts of polypropylene carbonate; 0 to 12 parts of 1, 4-butanediol; 50 to 55 parts of an acrylate monomer; 0.1 to 0.2 part of p-hydroxyanisole; 0 to 18 parts of sulfydryl silane; 0.1 to 0.3 part of an organic tin catalyst; 5-10 parts of a solvent; 100 to 150 parts of deionized water; belongs to the technical field of coatings.

The invention provides a preparation method of methacrylic acid 2-butoxyethyl ester, and belongs to the technical field of organic synthesis. According to the invention, p-hydroxyanisole (MEHQ) and 2, 2, 6, 6-tetramethylpiperidine oxide (TEMPO) are used as polymerization inhibitors at the same time, and the dual polymerization inhibitors are synergistically used, so that the auto-polymerization of methyl methacrylate (MMA) and 2-butoxyethyl methacrylate is reduced, and the conversion rate is increased.

The invention discloses a microwave curing-based coating material and a preparation method thereof. The microwave curing-based coating material comprises mixed resin, a microwave absorbing material, cellulose ether, a curing agent, a hyperbranched polymer, an active monomer, polyglycol modified epoxy acrylate, o-cresol glycidyl ether, p-hydroxyanisole, a plasticizer and an accelerant. During preparation, the mixed resin, the hyperbranched polymer, the active monomer, the polyglycol modified epoxy acrylate and the o-cresol glycidyl ether are mixed and stirred, the p-hydroxyanisole, the plasticizer and the accelerant are sequentially added and stirred, the microwave absorbing material and the cellulose ether are added and stirred, and the curing agent is added and stirred. The coating material disclosed by the invention can be quickly cured within dozens of seconds to dozens of seconds based on a microwave condition, has good corrosion resistance and adhesive property, and fundamentally and effectively solves the problem of high shrinkage rate generally existing in the adoption of the existing light-cured resin.

The diphenyl carbonate reactive distillation system comprises a reactive distillation tower, a reflux pipeline, a tower top reflux tank, a first condenser, a methanol recovery system, a reflux pump, a side extraction pipeline, a side extraction pump, a buffer tank, a discharge pipeline, a tower bottom pump and a flash tank, a tower top liquid material of the reactive distillation tower enters a tower top reflux tank through a reflux pipeline, and a gas material enters a methanol recovery system after being condensed by a first condenser; controlling the reflux ratio, and refluxing the material in the tower top reflux tank; the reactive distillation column is provided with a height-adjustable side line extraction opening for extracting by-products such as anisole; and separating the reaction organisms through a flash tank to obtain diphenyl carbonate. The device integrates chemical reaction and rectification separation, methanol is separated from a material refluxed at the top of the tower, by-products such as anisole are extracted from a side line, the thermodynamic equilibrium of the reaction is broken, and the reaction is pushed to proceed in the positive direction, so that the conversion rate is increased, and meanwhile, a plurality of by-products are obtained; and the side line extraction position is adjustable, safe and convenient.

The invention discloses a COF-based heterogeneous iodobenzene catalyst and its preparation method and application, belonging to the field of catalyst preparation technology. The COF-based heterogeneous iodobenzene catalyst is obtained by polymerizing a hydrazide monomer containing an iodophenyl group unit and 1,3,5-tris(4-formylphenyl)triazine; the structural formula of the hydrazide monomer containing an iodophenyl group unit is: The COF-based heterogeneous iodobenzene catalyst can be used as a catalyst for the chlorination reaction of anisole, catalyzing the chlorination reaction of anisole, achieving heterogeneous catalysis, and using a small amount, easy to recover, improving the utilization rate of the catalyst, and reducing the cost of anisole chlorination.

The invention provides a palladium nickel phosphide catalyst and a preparation method and application thereof. The catalyst comprises a catalyst carrier; and an active component, wherein the active component comprises nickel, palladium and phosphide; wherein nickel and palladium are loaded on the surface of the catalyst carrier in a monatomic form, the phosphide is nickel phosphide, and the nickel phosphide is loaded on the surface of the catalyst carrier. The preparation method comprises the following steps: pretreating the catalyst carrier to remove impurities; dipping the pretreated catalyst carrier in a mixed solution of a nickel source and a palladium source, drying and calcining to form a precursor A; dipping the precursor A in a phosphorus source solution, and drying and calcining to form a precursor B; and reducing the precursor B in a reducing atmosphere, and then passivating in an inert atmosphere containing oxygen to obtain the palladium nickel phosphide catalyst. The catalyst is applied to selective hydrogenation reaction of biomass derivatives (such as anisole and m-cresol), and shows high activity and high selectivity.

The invention relates to a catalyst for preparing anisole through phenol methanol etherification as well as a preparation method and application of the catalyst. The catalyst takes aluminum phosphate as a carrier and is doped with zirconium oxide; on the basis of the mole number of Al, the mole ratio of P to Al is (0.05-2): 1, and the mole ratio of Zr to Al is (0.08-0.20): 1. Dropwise adding the aluminum-zirconium mixed aqueous solution into the phosphorus source aqueous solution, stirring, standing and washing to obtain a solid sample; and drying and roasting the solid sample to obtain the aluminum phosphate catalyst. Under the action of the catalyst, phenol and methanol are catalyzed to generate anisole. Compared with the prior art, the phenol conversion rate is greater than or equal to 50%, the anisole selectivity is greater than or equal to 85%, highly toxic dimethyl sulfate and a large amount of alkali are not needed, the process is green, the cost is low, separation is simple, and the method is suitable for large-scale industrial production of anisole.

The application relates to an anti-aging high-whiteness BOPP matt white label film and a preparation method thereof, and belongs to the technical field of white label films. The anti-aging high-whiteness BOPP matt white label film comprises a matt layer, a core layer and a smooth layer arranged in sequence; the matt layer comprises random copolymerized polypropylene, 40-45 wt% high-density polyethylene, 2-4 wt% ethylene-2-allyl benzene methyl ether random copolymer and 0.1-0.5 wt% antioxidant; the core layer comprises homopolymerized polypropylene and 10-20 wt% white masterbatch, the white masterbatch comprises homopolymerized polypropylene, 5-10 wt% ultrahigh molecular weight polyethylene and 50-70 wt% surface-modified titanium white powder, and the organic coating agent used in the surface-modified titanium white powder is bis[(3-methyl dimethoxy silyl) propyl] polyoxypropylene. The label film has the advantages of anti-aging, high whiteness, good matt uniformity and good whiteness uniformity.

The invention provides a polymer type anti-wax pour point depressant and a preparation method thereof.The preparation method comprises the steps that long-carbon-chain alpha-olefin, short-carbon-chain acrylics, maleimide and 4-allyl anisole are dissolved in a solvent, then an initiator is added for a reaction, and the polymer type anti-wax pour point depressant is obtained; the prepared polymer type paraffin and pour point depressant can effectively act on wax crystals, such as a long carbon chain, an imide group, an ether bond, an ester group and the like, and has more acting groups and stronger acting effect compared with a conventional paraffin inhibitor, and the prepared polymer type paraffin and pour point depressant solves the problems of poor paraffin inhibition effect, poor pour point depression effect and high toxicity of a common oil-based polymer paraffin and pour point depressant.

The invention relates to a titanium complex catalyst, a preparation method of the titanium complex catalyst and application of the titanium complex catalyst in hydroxylation of anisole. Anisole and hydrogen peroxide react under catalysis of the titanium complex catalyst to obtain o-hydroxyanisole and p-hydroxyanisole. The invention provides a novel catalyst, active titanium and reactants are in full contact, and higher reaction activity is achieved; the catalyst has a certain space effect, can achieve a shape-selective catalysis effect, can generate more para-products, and improves the para-ortho ratio of hydroxyanisole.

The invention relates to palmitoyl tripeptide-38 and a preparation method and application thereof.According to the palmitoyl tripeptide-38, low-toxicity and biodegradable NFM and anisole are compounded according to the volume ratio of 1: 1, and the palmitoyl tripeptide-38 has strong polarity and moderate hydrophobicity and can completely replace DMF. According to the mixed solvent, the solubility of Fmoc amino acid monomers, activating reagents and resin is improved, the risk of reproductive toxicity is avoided, and the volatility is reduced compared with that of DMF (Dimethyl Formamide); the process is synergistically enhanced, namely, the mass transfer limitation of the traditional intermittent reaction is overcome through the synergism of the laminar shear effect and the ultrasonic cavitation effect of a continuous flow reaction device, so that the coupling reaction time of the palmitoyl tripeptide-38 is shortened, the occurrence rate of side reaction is reduced, and the universality verifies that the solvent system has excellent performance in synthesis of the palmitoyl tripeptide-38, and the solvent system is suitable for industrial production. And the coupling efficiency is stable.

The invention belongs to the technical field of electrolysis, and discloses a method for preparing p-hydroxyanisole through electrolytic oxidation of anisole. The method comprises the following steps: S1, adding anisole, an acylation reagent, an organic alkali proton trapping agent and an alkaline amine group-containing solvent into a single-chamber electrolytic bath together, starting electrification, carrying out electrolysis, and obtaining a product liquid containing p-methoxytrifluoroacetic acid phenyl ester in the single-chamber electrolytic bath after electrolysis is finished; the organic base proton trapping agent is at least one of N, N-diisopropylethylamine, tributylamine and tripropylamine; and S2, adding a saturated sodium bicarbonate aqueous solution into the product liquid containing p-methoxytrifluoroacetic acid phenyl ester in the step S1 to hydrolyze p-methoxytrifluoroacetic acid phenyl ester, and extracting to obtain p-hydroxyanisole. The selectivity of para-position and ortho-position products of methoxyl on anisole is regulated and controlled, so that the selectivity of p-hydroxyanisole prepared by the method is higher.

The application discloses a preparation method of o-bromoanisole. The o-bromoanisole is synthesized through three steps, anisole is used as raw material, p-sulfonic anisole is first synthesized, 2-bromo-4-sulfonic anisole is synthesized on the basis, and finally, the sulfonic group is removed to obtain o-bromoanisole. Since anisole is used as raw material, the problems of multiple by-products, low yield and low purity existing in the synthesis path of phenol are avoided. Meanwhile, all the raw materials of the application have low cost, the process steps are simple, and etherification is not needed. Meanwhile, since anisole is used as raw material, hydrobromic acid and hydrogen peroxide can be used in the intermediate step, the hydrobromic acid is oxidized to generate bromine, the reaction rate can be controlled, the reaction efficiency is improved, the waste of bromine is reduced, the purity of the prepared product can reach 99.4%, the yield reaches 96.26%, and the product can be applied on a large scale in industry.

The application provides a production method of 2-amino-4-acetylamino anisole, relates to the technical field of organic chemical synthesis, and comprises the following steps: continuously acetylating p-aminoanisole in a tubular reactor, neutralizing, crystallizing and drying to obtain an intermediate. The intermediate, concentrated sulfuric acid and a specific auxiliary A are mixed to form a substrate liquid, and the substrate liquid is subjected to a nitration reaction with a nitration mixed acid in a three-stage continuous reaction kettle. The auxiliary A is composed of perfluoropolyether oil, boron nitride nanosheet, polyethylene glycol perfluorooctyl ether block copolymer and lipophilic fumed silica. The nitration liquid is quenched, extracted and crystallized to obtain a nitration product. The nitration product is dissolved in ethanol, and catalytic hydrogenation is carried out in a fixed bed reactor. The hydrogenation product is subjected to post-treatment to obtain 2-amino-4-acetylamino anisole. The application remarkably improves the reaction selectivity, yield and product purity through the cooperation of the continuous process and the specific auxiliary, and the by-products are few, so that the method is suitable for industrial production.

The invention relates to a high-performance anti-caking UV varnish for soft packaging of cigarettes and a preparation method thereof. The UV varnish comprises the following components calculated by weight: 25-35% of a modified aliphatic polyurethane acrylate resin, 10-15% of a fatty acid-modified epoxy acrylate, 30-35% of propoxylated neopentyl glycol diacrylate, 10-20% of ethoxylated 1,6-hexanediol diacrylate, 5-12% of a reactive tertiary amine co-initiator, 6-10% of a photoinitiator combination, and 2.48-4.82% of an auxiliary agent combination. The combination of the main resin, monomer, photoinitiator, etc. adopted in the present invention can obtain a UV varnish having excellent adhesion, ethanol resistance, friction resistance, environmental protection and other properties. In addition, the matching of appropriate specific auxiliary agents, wax powder, a polysiloxane surface-modified nano-alumina particle dispersion, and p-hydroxyanisole can further enable the soft packaging paper for cigarettes to have appropriate surface hardness and a suitable friction coefficient, thereby significantly reducing the caking phenomenon.

The invention relates to the technical field of lithium ion battery material additives, and discloses a preparation method and application of a lithium trifluoroborate salt containing unsaturated bonds, the preparation method comprises the following steps: placing a poor solvent and a boron trifluoride anisole complex in a reactor under a low temperature condition, and uniformly stirring; adding an organic lithium salt containing unsaturated bonds into the reactor, and reacting under a low-temperature condition; then reacting at normal temperature to obtain a reaction solution after the reaction is completed; carrying out solid-liquid separation on the reaction liquid to obtain a lithium trifluoroborate crude product containing unsaturated bonds and filtrate; and re-dissolving and recrystallizing the lithium trifluoroborate crude product containing the unsaturated bond to obtain a finished product. Anisole is used as a reaction solvent, so that the product yield is increased; the usage amount of the anisole is small, and the anisole can be recycled after being properly recycled, so that the production cost is reduced; the method has the characteristics of simplicity in operation, high product yield, high product quality and low cost, is basically free of three wastes, is environment-friendly and is suitable for industrial production.

The invention relates to a synthesis process for co-production of p-hydroxyanisole and o-hydroxyanisole, anisole and hydrogen peroxide are used as raw materials, and under the action of a catalyst and an auxiliary agent, the content of p-hydroxyanisole and o-hydroxyanisole can be adjusted. The additive is prepared by taking benzothiophene as a raw material through alkyl ether, ethynylation and ring closing reaction, has certain solvent effect and limiting effect, and can change the proportion of p-hydroxyanisole to o-hydroxyanisole in a product.