151 results about "SOY LECITHIN" patented technology

The invention discloses a macrophage-targeting inhalable nano material, a preparation method thereof and application of the inhalable nano material in treatment of sepsis myocarditis, and belongs to the technical field of medicines. The nano-material is a nano-liposome, the nano-liposome comprises a mannose modified nano-liposome microsphere, and the mannose modified nano-liposome microsphere comprises a liposome skeleton shell layer, a drug and a targeting layer; the liposome skeleton shell layer comprises soybean lecithin and cholesterol; the medicine comprises quercetin and TPPU (Thermoplastic Polyurethane); and the targeting layer is formed by connecting mannose modified DSPE-PEG2000 to the outer surface of the liposome skeleton shell layer. The nano material can accurately target macrophages at a cardiac inflammation part, has a multi-target-point synergistic effect, is more convenient and faster in administration, remarkably improves the safety and comprehensively improves the treatment effect.

The invention relates to a novel camellia saponin derivative feed additive and a preparation method thereof, and belongs to the technical field of feed additives. The modified chitosan is used in the flocculation and impurity removal process for preparing the camellia oleifera saponin derivative, and the modified chitosan reduces the loss of effective components caused by flocculation and impurity removal while ensuring the purity of the camellia oleifera saponin derivative; soybean lecithin and gelatin are used as capsule walls, the camellia saponin derivative and pyropheophorbide-a are wrapped, pyropheophorbide-a can generate singlet oxygen under excitation of visible light, phospholipid bonds are damaged, the camellia saponin derivative is released, and therefore the slow release effect is achieved; the novel camellia saponin derivative feed additive prepared by the invention has good antibacterial property and timeliness.

The invention provides eye protection liquid for improving eye microcirculation and a preparation method thereof, and belongs to the technical field of medical configuration products. The composition comprises the following components: surface-modified magnetic nanoparticles, a calendula extract, a fermented dogwood extract, xanthophyll, taurine, sodium hyaluronate, hydrolyzed sodium hyaluronate, soya bean lecithin, borneol and fermented vegetable oil. The efficiency of active ingredients is improved through a double-fermentation technology, magnetic targeting and multi-channel compounding are combined, and the preparation method has remarkable advantages in the field of improving periorbital microcirculation. The traditional Chinese medicine composition has an obvious relieving effect on asthenopia and dry skin around eyes; the components of the eye microcirculation eye protection liquid are mild, and adverse reactions such as allergy cannot be caused.

This invention discloses a method for preparing a diglyceride nanostructured lipid carrier hydrogel, comprising the following steps: mixing vegetable oil and diglyceride at a mass ratio of 1:1-3 as phase A; using an aqueous solution of soybean lecithin, tea saponin, and glycerol as phase B; adding phase B to phase A, followed by emulsification, ultrasonic treatment, and finally cooling to room temperature to obtain a diglyceride nanostructured lipid carrier; adding the diglyceride nanostructured lipid carrier to the hydrogel and mixing to obtain the diglyceride nanostructured lipid carrier hydrogel. This invention also discloses the application of the above-mentioned diglyceride nanostructured lipid carrier hydrogel. The diglyceride nanostructured lipid carrier hydrogel of this invention not only has good sun protection, antioxidant, and anti-glycation properties, but can also encapsulate unstable cosmetic raw materials.

The invention belongs to the technical field of traditional Chinese medicines and cosmetics, and particularly relates to eutectic resveratrol, a liposome thereof, a preparation method and application of the eutectic resveratrol. The eutectic resveratrol is prepared from the following raw materials: resveratrol, amino acid and glycerol; the amino acid is selected from one of proline, lysine and arginine. The eutecticevaporate resveratrol liposome is prepared from the following raw materials: soybean phospholipid, cholesterol and eutecticevaporate resveratrol, the mass ratio of the soybean phospholipid to the cholesterol is (1-9): 1, and the mass ratio of the sum of the mass of the soybean phospholipid and the cholesterol to the mass of the eutecticevaporate resveratrol is 1: (0.5-2). A method capable of improving the solubility and stability of resveratrol is found, the eutectic resveratrol liposome which is stable in particle size and PDI and excellent in zeta potential and has certain anti-oxidation and antibacterial performance is prepared, the solubility, stability and bioavailability of resveratrol (RES) are improved, and the resveratrol liposome is suitable for being used as an anti-inflammatory drug. And a new thought is provided for further development and application research of resveratrol (RES).

This invention discloses a recombinant collagen liposome, its preparation method, and its application. The recombinant collagen liposome comprises 1-10 parts recombinant type XVII collagen, 2-15 parts soybean lecithin, 0.3-2 parts tocopherol, 0.5-7 parts antioxidant, 20-54 parts glycerol, and Dendrobium officinale enzymatic hydrolysate to a total weight of 100 parts. This invention improves the stability and transdermal absorption of recombinant type XVII collagen by encapsulating it in liposomes. The prepared recombinant collagen liposomes not only have a high encapsulation efficiency but also retain excellent barrier repair and anti-wrinkle effects after 8 weeks of storage, making them suitable for use in cosmetics.

A composition comprising a glucagon-like peptide 1 (GLP-1) agonist for sublingual or buccal administration, wherein the composition comprises one or more agents selected from the group consisting of; sodium glycodeoxycholate; sodium deoxycholate; carboxymethyl cellulose; sodium alginate; SNAC (salcaprozate sodium); a non-ionic ester alkoxylate (or alkanoic acid ester alkoxylate); and soy lecithin.

The invention relates to a eugenol liposome / chitosan / polyoxyethylene hydrophobic electrospun fibrous membrane and a preparation method thereof, and the method comprises the following steps: based on soybean lecithin and cholesterol, adding eugenol and Tween 80, preparing a lipid solution, injecting the lipid solution into water or a phosphate buffer solution, and preparing an eugenol liposome suspension with the eugenol embedding rate greater than 88%; preparing a cross-linked chitosan acetic acid solution based on chitosan and a cross-linking agent; preparing a polyoxyethylene acetic acid solution, and mixing the cross-linked chitosan acetic acid solution with the polyoxyethylene acetic acid solution to obtain a base material spinning solution; mixing the eugenol liposome suspension with a base material spinning solution to prepare a final spinning solution, and preparing the eugenol liposome / chitosan / polyoxyethylene hydrophobic electrospinning fiber membrane by adopting an electrostatic spinning method. The embedding rate of eugenol is high, the water contact angle of the fiber membrane can reach 90 degrees or above, the slow release effect on eugenol is good, and the antibacterial and fresh-keeping effects are improved.

The present invention belongs to the technical field of semen cryopreservation, and more specifically, relates to sheep semen freezing solution and semen preservation method. The sheep semen freezing solution components of the present invention include Tris, citric acid, fructose, lactose, trehalose, penicillin, streptomycin, soy lecithin, nobiletin, glycerol and water. By using a specific content of nobiletin as an effective antioxidant component of a sheep sperm cryopreservative, it plays an antioxidant role when the sperm is frozen, making the sperm more stable during the cryopreservation process. After adding nobiletin, the vitality and motility of sheep sperm after freezing and thawing can be significantly improved. It effectively reduces the oxidative stress damage of sperm during the freezing process and improves the antioxidant capacity of sperm.

The application provides a topical traditional Chinese medicine composition for treating vulvar leukoplakia and a preparation method thereof. The composition is composed of traditional Chinese medicinal materials such as angelica, cortex psoraleae and barks of dictamnus dasycarpus, and a penetration enhancer, an activating agent and a moisturizing agent. The penetration enhancer is composed of soybean lecithin, phosphatidylethanolamine and cholesterol, the activating agent is sodium cholate, sodium deoxycholate and sodium taurocholate, and the moisturizing agent is eucalyptus oil. The drugs are compatible to exert the effects of clearing heat and drying dampness, cooling blood and nourishing yin, activating blood and resolving stasis, warming yang and dispelling cold and supporting healthy qi and tonifying the body resistance. The traditional Chinese medicine composition is prepared through supercritical extraction, micronization treatment, solution preparation and intermittent ultrasonic homogenization. The traditional Chinese medicinal materials are used for treating the etiology, pathogenesis and symptoms of vulvar leukoplakia, the penetration enhancer reduces the skin barrier function, the activating agent enhances the drug activity and permeability, and the moisturizing agent maintains the skin moisture and assists in anti-inflammation. The clinical application effectively relieves the symptoms of patients with vulvar leukoplakia, improves the pathological state of local skin and improves the treatment effect, thereby providing a new effective option for the treatment of vulvar leukoplakia.

The invention discloses a preparation method of phospholipid type DHA (docosahexaenoic acid) and application of the phospholipid type DHA in preparation of products for improving allergy symptoms, and belongs to the technical field of preparation and application of the phospholipid type DHA. Obtaining free DHA from the fish oil; soybean lecithin and free DHA are mixed, n-hexane is added for ultrasonic dissolution, enzyme is added after dissolution, nitrogen is filled for sealing for reaction, enzyme is removed after the reaction is finished, an organic solvent is removed from reaction liquid through rotary evaporation, mixed grease is obtained, and the phospholipid type DHA is obtained through purification. In the aspect of improving allergy, the phospholipid DHA prepared by the invention has a better mixing effect than fish oil and soybean lecithin, and has a good application prospect in the aspect of preparing functional foods, medicines or medicine carriers.

The present application relates to the technical field of vaccine production, in particular to a preparation method of a Sapindus saponin veterinary vaccine adjuvant, comprising: determining the limit concentration of Sapindus saponin with a hemolysis rate lower than 5% and preparing the vaccine adjuvant; determining the limit concentration of Sapindus saponin with a hemolysis rate lower than 5% against red blood cells by spectrophotometry; preparing the vaccine adjuvant by dialysis; and the vaccine adjuvant contains soybean lecithin and cholesterol in a weight ratio of 1:1. The present application first determines the safe use concentration of Sapindus saponin through a standard hemolysis experiment, ensures that the hemolysis rate of the prepared adjuvant meets the safety requirements, and avoids adverse reactions after injection; at the same time, the present application uses soybean lecithin and cholesterol as raw materials, and prepares the nano-liposome adjuvant embedding Sapindus saponin by dialysis, which does not require complex process operation, has low preparation cost, and has safety and practicability, and can effectively assist the vaccine to induce the body to produce stronger immune response and improve the protection effect of the vaccine.

This application relates to the field of veterinary drug technology, and discloses a transdermal absorption-enhancing ointment and its preparation process. The ointment components include white petrolatum, anhydrous lanolin, caprylic / capric triglycerides, hydrophobic fumed silica, and a highly fluid active permeation-enhancing phase. The permeation-enhancing phase contains active drugs and soybean lecithin, which self-assemble to form an inverse micelle aggregate. Soybean lecithin cross-links with the silanol groups on the surface of silica to form an intermolecular hydrogen bond network, constructing a sterically hindered framework within a continuous lipid matrix to prevent the polar drug-loaded phase from permeating and separating upon heating. Simultaneously, the inverse micelle structure effectively improves the transdermal absorption rate of the drug. The preparation process controls the lipid crystallization kinetics through slow cooling under negative pressure and micro-shear dynamic rheology. This invention solves the problems of easy precipitation upon heating, low transdermal efficiency, and poor rheological properties in traditional ointments, resulting in a product with a stable physical structure and good pseudoplastic texture.

This invention discloses a method for preparing hydrophilic drug nanoliposomes based on microfluidic-low-shear coupling double emulsion and the hydrophilic drug nanoliposomes prepared according to the following method: (1) Prepare aqueous solutions of hydrophilic drugs and chloroform solutions of soybean lecithin respectively; (2) Add the chloroform solution of soybean lecithin to the chamber as the oil phase, and inject the aqueous solution of hydrophilic drugs into the oil phase in the low-shear stirring field through a microtube under low-speed stirring and shearing, and collect the W / O pre-emulsion sample; (3) Use the W / O pre-emulsion sample as the dispersed phase, and inject it into the external aqueous phase in the same way as in step (2), and emulsify it under low-speed stirring and shearing to form a W / O / W double emulsion; (4) Remove the chloroform by vacuum evaporation of the W / O / W double emulsion to obtain hydrophilic drug nanoliposomes. The prepared Ganoderma lucidum polysaccharide nanoliposomes have a particle size controlled at 200-300 nm, a polydispersity index of about 0.2, and an encapsulation efficiency of more than 70%, which is more than twice that of the traditional thin film hydration method. It solves the technical problem of low encapsulation efficiency of water-soluble macromolecular Ganoderma lucidum polysaccharides.

The invention discloses a kind of penetration-promoting composition and its preparation method and application, belong to the field of cosmetic technology, the penetration-promoting composition, including the components of the following parts by mass: 0.5~8 parts of hydrolyzed sodium hyaluronate, 5~20 parts of stabilizers, 12~25 parts of yeast / rice fermentation product filtrate, 40~80 parts of solvents; the stabilizer includes decapeptide-4, soy lecithin, sodium carboxymethyl cellulose, polyethylene glycol surfactant in a mass ratio of (0.05~0.4): (0.05~0.4): (0.08~0.5): 1. The present invention, under the joint action of hydrolyzed sodium hyaluronate, stabilizer, yeast / rice fermentation product filtrate, from improving the antioxidant effect, stability, repairing skin barrier of composition, improving the moisturizing effect and skin elasticity of composition, effectively reducing surface tension, improving the permeability and wettability of liquid, destroying the permeability of cell membrane, on the basis of not destroying skin barrier, promoting effective ingredient to penetrate and reach the deep layer of skin, gently releasing effective ingredient, promoting skin to be effectively absorbed.

The present invention relates to ophthalmic compositions comprising at least one substance of at least one nicotinic acetylcholine receptor (nAChR) modulator, in particular varenicline, megamine and derivatives thereof, and / or the endogenous Kennedy metabolic pathway, as well as salts and derivatives or pharmaceutically acceptable salts of these substances, and choline-containing phospholipids, salts and derivatives of these substances. From these groups, particularly preferred are choline, phosphocholine, CDP-choline (citicoline), phosphatidylcholine (e.g. Lecithin having a phosphatidylcholine content of > = 80% by weight, e.g. Soybean lecithin), ethanolamine, phosphoethanolamine, CDP-ethanolamine, phosphatidylethanolamine, L-alpha-glycerophosphorylcholine, phosphatidylcholine, phosphatidylethanolamine.

The invention discloses a loratadine oral liquid and a production process thereof. Comprising the following raw materials in parts by weight: 0.5 to 0.6 part of loratadine, 5 to 6 parts of beta-cyclodextrin, 10 to 12 parts of polyethylene glycol 400, 8 to 10 parts of glycerol, 6 to 8 parts of propylene glycol, 0.3 to 0.4 part of sucralose, 0.2 to 0.3 part of stevioside, 15 to 18 parts of maltitol, 1 to 1.2 parts of citric acid, 0.5 to 0.6 part of malic acid, 0.1 to 0.15 part of disodium EDTA (Ethylene Diamine Tetraacetic Acid), 0.8 to 1 part of vitamin C, 0.3 to 0.4 part of xanthan gum, 0.5 to 0.6 part of sodium carboxymethyl cellulose and 0.4 to 0.5 part of lemon essence. The composition comprises the following components in parts by weight: 0.1-0.15 part of menthol, 2-3 parts of hawthorn extract, 1.2-1.5 parts of soya bean lecithin and the balance of purified water, totaling 100 parts. The loratadine is clathrated by the beta-cyclodextrin, the absorption promotion effect of the soya bean lecithin is combined, and the compound sweetening agent, the compound stabilizer and the natural flavor substance are matched, so that the problems of poor solubility and obvious bitter taste of the loratadine are solved, and the stability and bioavailability of the product are also improved.

The invention discloses soybean phospholipids and an extraction method thereof, and belongs to the technical field of soybean phospholipids, the extraction method of soybean phospholipids comprises the following steps: selecting fresh soybean oil leftovers as an extraction raw material, carrying out centrifugation, acetone deoiling and ethanol extraction to obtain an ethanol extraction liquid, finally adding attapulgite composite cross-linked chitosan microspheres into the ethanol extraction liquid, and carrying out centrifugation, acetone deoiling and ethanol extraction to obtain the soybean phospholipids. And further removing impurity molecules to obtain the soybean phospholipid with high stability and high soybean lecithin content. According to the present invention, by using the multiple pore structures and the electrostatic interaction of the attapulgite composite cross-linked chitosan microspheres, the impurity macromolecules and the polar inositol phospholipid, cephalin and other compounds having competitive dissolution with the soybean lecithin are separated so as to increase the soybean lecithin content in the soybean lecithin; moreover, tea polyphenol is also grafted on the attapulgite composite cross-linked chitosan microspheres, so that free radicals can be cleared through a hydrogen supply mechanism, the phospholipid oxidation process is blocked, the dual functions of high stability and high antioxidant activity are realized, and the quality of the obtained soybean phospholipid is improved.

The invention discloses a method for constructing food-grade Janus nanoparticles based on thermodynamic equilibrium and instantaneous nano precipitation, and belongs to the technical field of nano materials. According to the preparation method, hydrophobic zein and soybean lecithin are taken as raw materials, a method of combining anti-solvent precipitation and thermal induction is adopted, and three-phase interfacial tension of a system is adjusted by regulating and controlling parameters such as temperature and surfactant concentration in a rapid exchange process of a solvent, so that composite nanoparticles are converted into dumbbell-shaped structures; finally, the food-grade Janus nanoparticles with uniform particle size distribution and stable properties are formed. The method for constructing the food-grade Janus nano-particles is easy and convenient to operate, low in cost and suitable for large-scale industrial production, and meanwhile the constructed Janus nano-particles have good stability and are widely applied to the fields of food, medicine or cosmetics.

The invention discloses prebiotic soft fried dough twists and a making method thereof, and belongs to the technical field of food. The fried dough twist disclosed by the invention is prepared from the following raw materials in parts by mass: 132 to 169.5 parts of a dough base material, 5 to 6 parts of resistant dextrin, 7 to 9 parts of fructo-oligosaccharide microcapsules, 6 to 8 parts of isomaltitol, 1.5 to 2 parts of stachyose, 0.5 to 1.0 part of soybean lecithin and 0.01 to 0.03 part of vitamin E. The prebiotic retention rate is synergistically increased through microcapsule coating and a making process, the aging resistance of the fried dough twist is improved through synergistic moisturizing of resistant dextrin and fructo-oligosaccharide microcapsules, white granulated sugar is partially replaced by isomaltitol, stachyose and other sugar parts with low glycemic index, and the taste of the fried dough twist is improved. And the resistant dextrin with high dietary fiber content and the fructo-oligosaccharide prebiotics are matched, so that the product not only meets the sweet taste requirement, but also meets the healthy diet pursuit of modern consumers on low sugar, high fiber and high prebiotics.

The invention discloses a preparation method of a biomass-based slow-release agent for repairing polycyclic aromatic hydrocarbon polluted underground water, which comprises the following steps: 1, preparation of soybean milk fermentation liquor: weighing soybeans, soaking the soybeans in ultrapure water according to a solid-to-liquid ratio of 1: 20-1: 50 for 12-48 hours, pulping, and adding ultrapure water until the volume is 500mL to obtain a soybean milk matrix; inoculating 10mL of polycyclic aromatic hydrocarbon polluted underground water indigenous microorganism bacterial liquid into the soybean milk matrix, and carrying out closed fermentation under a constant-temperature oscillation condition, 2, preparation of a multifunctional composite slow-release agent: weighing 35-60 parts by weight of FeSO4. 7H2O, 1-5 parts by weight of rhamnolipid, 5-10 parts by weight of humic acid, 1-5 parts by weight of methionine, 5-10 parts by weight of peanut peptide, 1-10 parts by weight of soybean lecithin, 3-10 parts by weight of a yeast extract and 40-60 parts by weight of the soybean milk fermentation broth prepared in the step 1; the method has the beneficial effects that the degradation efficiency on organic pollutants such as polycyclic aromatic hydrocarbon is remarkably enhanced, and a reliable material basis and theoretical support are provided for engineering application of an underground water bioremediation technology.

The present application relates to the technical field of fuel additive, in particular to a high-energy cleaning type composite solid fuel additive and a preparation method thereof. The additive comprises the following raw materials: myristic acid, stearic acid, a composite catalytic unit, modified soybean lecithin, tributyl borate, butylated hydroxyanisole and polyethylene glycol monostearate. The composite catalytic unit is prepared by coordination of diethyl phosphinic acid with manganese chloride, lanthanum chloride and cerium chloride; the modified soybean lecithin is obtained by ammonolysis and intramolecular lactonization and contains a five-membered cyclic phosphonate structure. During preparation, the components are dispersed by ultrasonic dispersion after being loaded on a melting carrier, and then solidified and formed. The additive realizes cleaning and repair integration through double-metal synergistic catalysis and combustion strengthening, and the composite carrier can controllably release and adapt to all working conditions. The product is soft and easy to discharge, has high economic efficiency and environmental compatibility, and is convenient to store and use.

This invention relates to the field of food technology, and in particular to a protein powder that promotes bowel movements. To address the problems of some protein powders with added dietary fiber, such as poor compatibility between dietary fiber and protein, poor solubility, rough texture, and insignificant bowel improvement effects, ultimately leading to constipation, this invention comprises whey protein powder, casein powder, inulin, fructooligosaccharides, psyllium husk powder, soybean lecithin, and β-mannanase. This protein powder offers dual benefits of protein supplementation and intestinal health regulation. It efficiently supplements the protein needed by the human body, improves protein absorption and utilization, and is suitable for individuals with lactose intolerance and weak intestinal function. Simultaneously, through the synergistic effect of prebiotics, dietary fiber, and enzymes, it gently improves constipation symptoms, regulates intestinal flora balance, enhances intestinal peristalsis, and fundamentally protects intestinal health.

This invention provides a sea cucumber ganglioside extract nanoliposome with neuroprotective activity and its preparation method. The preparation steps are as follows: thawed frozen ready-to-eat sea cucumber, chopped, freeze-dried, pulverized, and sieved to obtain freeze-dried powder. The powder is then extracted using supercritical CO2 extraction and rotary evaporation to remove the solvent. This powder is then dissolved in anhydrous ethanol with soybean lecithin and β-sitosterol as the oil phase, mixed with PBS buffer, stirred, and hydrated to obtain a proemulsion. After centrifugation, the precipitate is resuspended and sonicated to obtain the product. This invention uses supercritical CO2 extraction, and the extract contains 59.70 μg / g of gangliosides, with glycosphingolipids accounting for 96.372% of sphingolipids, resulting in enrichment of the target components. Simultaneously, these nanoliposomes significantly delay Aβ1-42-induced paralysis. The 30 μg / mL group showed a 2.75-fold increase in motor ability and a 30% increase in reproductive function compared to the control group, and a 47% reduction in ROS levels. The neuroprotective effect is superior to that of the unencapsulated extract, providing a new approach for adjuvant intervention in neurodegenerative diseases such as Alzheimer's disease, and has broad application prospects in the functional food field.

The invention belongs to the field of cosmetic preparation, and particularly relates to anti-inflammatory and repairing heparin sodium liposome gel and a preparation method thereof. The heparin sodium liposome gel disclosed by the invention is prepared from the following components in percentage by mass: 1.0 to 3.0 percent of heparin sodium liposome, 11.8 to 14.1 percent of a humectant, 0.2 to 0.5 percent of triethanolamine, 0.3 to 0.7 percent of a thickening agent, 0.1 to 0.2 percent of a preservative, 0.1 to 0.2 percent of essence and the balance of water. Natural raw materials such as soybean lecithin and phytosterol are adopted, and carboxymethyl chitosan and polyethylene glycol are combined to optimize a membrane structure, so that the transdermal efficiency and the anti-inflammatory effect of heparin sodium are remarkably improved; a plurality of humectants (propylene glycol, glycerol, betaine and the like) are added, so that the skin barrier can be repaired, and good stability, moisture retention, anti-inflammation and repairing effects are achieved.

The invention discloses chewing gum for promoting rapid recovery of cognitive fatigue as well as a preparation method and application of the chewing gum. Comprising the following raw material components: linalyl acetate, gum base, D-mannitol, erythritol, purified water, caprylic / capric triglyceride, soya bean lecithin, Arabic gum, carnauba wax and potassium sorbate. The chewing gum is used after work fatigue or in a cognitive fatigue state at a high mental load post, and the specific process is as follows: a user puts one linalyl acetate chewing gum into the mouth in a room at the temperature of 20-30 DEG C, slowly chews the linalyl acetate chewing gum at the rhythm of 20-40 times per minute, discards the linalyl acetate chewing gum after chewing the linalyl acetate chewing gum for 4-6 minutes, and closes the eyes to have a rest for 15-20 minutes. The chewing gum disclosed by the invention can effectively promote rapid recovery of cognitive fatigue of high-mental-load working people and promote rapid recovery of fatigue of important post personnel such as unmanned aerial vehicle operation and radar monitoring, and the error rate and the accident rate are reduced.

The invention relates to a bacterial cellulose high-swelling-rate edible hydrogel sheet and a preparation method thereof. The bacterial cellulose high-swelling-rate edible hydrogel sheet comprises bacterial cellulose, kappa-carrageenan, glucomannan and microgel composite components. The bacterial cellulose, the kappa-carrageenan and the glucomannan are compounded to construct a three-dimensional network with high strength and high porosity, so that the hydrogel sheet can be quickly swelled in gastric juice, provides satiety and is finally disintegrated into a fiber suspension which is easy to discharge. By introducing a microgel composite component constructed by beta-cyclodextrin including epsilon-polylysine, kappa-carrageenan and soya bean lecithin, multiple functions of bacteriostasis, oxidation resistance, loading of fat-soluble active components and the like are further realized, and the taste and stability of the product are remarkably improved.

The present invention discloses a nano-liposome loaded with fish collagen peptides, its preparation method and application, belonging to the fields of polypeptide and bioproduction processing. In the present invention, fish collagen peptide solid powder is dissolved in pure water, and further, soybean lecithin and phytosterol are added to the collagen polypeptide solution. The above substances are fully mixed by high-speed homogenization and whipping, and then the emulsion is introduced into a microfluidic homogenizer for high-pressure homogenization. Subsequently, the emulsion is diluted and added to tangential flow ultrafiltration, and diluted and ultrafiltered repeatedly for multiple times to separate the liposome from the free peptide, obtain high-purity liposomes, and at the same time realize the recovery and reuse of the free peptide. Compared with the current mainstream preparation methods, its preparation method has the advantages of not introducing organic solvents, simplifying the process, recycling the unentrapped raw materials, and reducing raw material waste.

The invention relates to the technical field of aquaculture, and discloses an artemia bait preparation and feeding method for cynoglossus semilaevis larvae in the bait transfer period, and the method comprises the following steps: constructing a basic artemia suspension; putting the artemia into an interface induction pretreatment solution containing soybean lecithin and taurine, and stirring at constant temperature under low-temperature and micro-inflation conditions, so that the artemia forms an induction adsorption layer and reaches pre-balance; then raising the temperature and adding microparticle compound feed in batches to carry out gradient competitive enhancement, so as to prepare enhanced artemia bait; and finally, carrying out collaborative feeding according to a preset strategy after cleaning. According to the method, interface induction and physiodynamic regulation are utilized, wrapping of the micropellet feed on the body surface of artemia and filling of the micropellet feed in the intestinal tract are achieved, the bait loading efficiency is remarkably improved, the problems that larvae and juveniles refer to feed and are insufficient in nutrition intake in the bait transfer period are effectively solved, the survival rate is increased, and water pollution is reduced.

The invention discloses an ergosterol peroxide composite sustained-release agent as well as a preparation method and application thereof, and belongs to the technical field of medical antitumor drug preparations. The invention discloses a preparation method of an ergosterol peroxide composite sustained-release agent, which comprises the following steps: compounding ergosterol peroxide powder and soybean lecithin (Soybean lecithin, SPC, purity gradegt, 90%) through methanol, and sequentially carrying out the steps of normal hexane washing, reduced pressure rotary evaporation, filtration and ultrasonic treatment, so as to obtain the ergosterol peroxide composite sustained-release agent. Compared with the anti-tumor effect of pure ergosterol peroxide, the ergosterol peroxide has the characteristics of long circulation, low toxicity, strong targeting property, better treatment effect and the like.