17 results about "White petrolatum" patented technology

The invention relates to cream for repairing radiodermatitis and a preparation method of the cream, and belongs to the technical field of biomedical skin treatment. The cream consists of the following components in percentage by weight: 8% of glycerin monostearate, 6% of stearic acid, 5% of white vaseline, 4% of liquid wax, 1-2% of tea tree oil, 1-2% of eugenol, 1-2% of vitamin E, 3% of trehalose, 8% of polyethylene glycol (PEG-400), 10% of glycerol, 0.5% of methylparaben, 1% of triethanolamine and the balance of purified water. According to the cream disclosed by the invention, the natural traditional Chinese medicine component eugenol and the natural substance vitamin E are utilized to synergistically enhance the anti-oxidation and bacteriostatic effects, and the tea tree oil, the trehalose and other effective components are utilized to repair radiodermatitis from multiple aspects of anti-inflammation, bacteriostasis, antioxidation, promotion of skin barrier repair and the like. The cream is simple in component, good in treatment effect, high in safety and convenient to produce and process, and can be popularized and applied to treatment of radiodermatitis.

This application relates to the field of veterinary drug technology, and discloses a transdermal absorption-enhancing ointment and its preparation process. The ointment components include white petrolatum, anhydrous lanolin, caprylic / capric triglycerides, hydrophobic fumed silica, and a highly fluid active permeation-enhancing phase. The permeation-enhancing phase contains active drugs and soybean lecithin, which self-assemble to form an inverse micelle aggregate. Soybean lecithin cross-links with the silanol groups on the surface of silica to form an intermolecular hydrogen bond network, constructing a sterically hindered framework within a continuous lipid matrix to prevent the polar drug-loaded phase from permeating and separating upon heating. Simultaneously, the inverse micelle structure effectively improves the transdermal absorption rate of the drug. The preparation process controls the lipid crystallization kinetics through slow cooling under negative pressure and micro-shear dynamic rheology. This invention solves the problems of easy precipitation upon heating, low transdermal efficiency, and poor rheological properties in traditional ointments, resulting in a product with a stable physical structure and good pseudoplastic texture.

The application provides a white-borneol apricot kernel face mask liquid and a preparation method and application thereof, and relates to the technical field of cosmetics. The preparation raw materials of the white-borneol apricot kernel face mask liquid provided by the application include white petrolatum 5-20 parts, mono-diglyceride 1-10 parts, methyl p-hydroxybenzoate 0.01-8 parts, glycerol 1-10 parts, butanediol 0.05-10 parts, Tween-80 0.05-12 parts and compound extraction liquid 10-30 parts in terms of weight percentage. The white-borneol apricot kernel face mask liquid provided by the application has good moisturizing effect, is cold and heat resistant, has good stability and meets the microbial detection standard of cosmetics.

The invention provides a calcipotriol ointment and a preparation method thereof.The ointment preparation is prepared from, by weight, 0.005 part to 0.01 part of calcipotriol, 5 parts to 10 parts of tussilagone, 8 parts to 23 parts of glycerin monostearate, 20 parts to 50 parts of white vaseline, 10 parts to 20 parts of paraffin, 20 parts to 40 parts of liquid paraffin, 15 parts to 45 parts of polyethylene glycol 400 and 8 parts to 12 parts of propylene carbonate.The formula of the calcipotriol ointment is improved; a certain proportion of tussilagone is added into the prescription, and the preparation method is improved, so that the defect that calcipotriol is easy to decompose is overcome, the problem of unstable calcipotriol content is solved, the stability of the calcipotriol ointment is improved, the content of related substances of the calcipotriol ointment is reduced, and the calcipotriol ointment has a synergistic effect in the aspect of treating psoriasis.

An eye drop type pharmaceutical composition comprising lipids, white petrolatum, and liquid paraffin, wherein the ophthalmic pharmaceutical composition comprises 3 to 500 milligrams of lipids, 100 to 250 milligrams of white petrolatum, and 1 to 797 milligrams of liquid paraffin per gram.

This invention belongs to the field of pharmaceutical formulation technology and relates to a clobetasol propionate ointment and its preparation process. The ointment comprises clobetasol propionate, an emulsifier, a solubilizer, a stabilizer, a secondary stabilizer, and an ointment base. The emulsifier is Tween-80, the solubilizer is propylene glycol, the stabilizer is povidone K15 or povidone K25, the secondary stabilizer is potassium chloride, and the ointment base is white petrolatum. This invention, by adding a stabilizer and a secondary stabilizer and screening their types, prepares a clobetasol propionate ointment that exhibits low impurity content and good stability during long-term storage. Furthermore, the preparation process is simple and easy to operate, facilitating industrial production.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a local external cream composition for treating psoriasis. The topical external cream composition for treating psoriasis is prepared from deaminated tyrosine, azone and a matrix, wherein the matrix is prepared from liquid paraffin, sorbitol, an emulsifying agent, tween-80, white vaseline, beewax, glycerin monostearate, solid paraffin and the like according to a specific weight percentage. By optimizing a prescription and a process, the cream composition which is good in stability, high in transdermal absorption efficiency and capable of effectively delivering DAT to a skin focus is prepared, psoriasis-like skin lesion is effectively improved, inflammation and epidermal hyperplasia are relieved, and the cream composition is good in safety. A brand-new, effective and safe external medicine selection and application are provided for the field of psoriasis treatment by taking the deaminated tyrosine as an active component.

The application belongs to the technical field of medicines and the field of ophthalmic preparations, and provides a stable erythromycin ointment composition without preservatives and a preparation method thereof. Through pre-wetting dispersion of erythromycin and liquid paraffin, construction of a white vaseline-liquid paraffin heat-treated oil matrix, low-moisture control, final mixing and redispersion, and nitrogen headspace replacement design, the dispersion state, content uniformity and headspace oxygen level of erythromycin particles are cooperatively controlled, the dispersion stability and chemical stability are improved, the problem that intensive dispersion and stable protection and mild processing and clean production control cannot be considered at the same time is solved, and the stable erythromycin ointment composition without preservatives is suitable for the production of ophthalmic semi-solid preparations without preservatives.

The present application belongs to the technical field of external preparations of traditional Chinese medicine, and relates to a cream containing imperatorin and capable of promoting skin wound healing and a preparation method thereof. The cream takes imperatorin and puerarin as core effective components, magnesium lithium silicate and sodium hyaluronate as synergistic repair components, sorbitan oleate and lanolin as emulsifiers, refined sesame oil, squalane and white petrolatum as oil phase matrix, and further includes glycerol, and the rest is deionized water. Animal experiment results show that the cream can promote collagen fiber generation of granulation tissue, promote polarization of repair type macrophages, significantly optimize repair quality and reduce scar formation while improving wound healing rate, and has good safety. The preparation process is stable and controllable, and is suitable for industrial production. The cream can be used for I and II degree mild burn and scald, skin abrasion and other traumatic wounds, and is also suitable for skin problems such as postoperative wound repair of medical beauty and hand and foot chapped skin, has wide clinical application range, and has good application prospect and popularization value.

The invention discloses a chemical detection method for oculent.The chemical detection method relates to the technical field of chemical analysis, the oculentcomprises ganciclovir, yellow vaseline, lanolin, liquid paraffin, white vaseline, glycerin, ethylparaben and vitamin E. The method comprises the following steps that (a) the content of ganciclovir in the oculent.The content of ganciclovir in the oculent.The content of ganciclovir in the oculentis is measured through a high performance liquid chromatography; (b) carrying out quality control on the lanolin raw material, namely measuring an acid value, a saponification value and a peroxide value; (c) carrying out wool fat related quality monitoring on the oculentum finished product, wherein the wool fat related quality monitoring comprises determination of a peroxide value; according to the method, chromatographic conditions are optimized, an exclusive impurity detection method is established, and raw materials are associated with finished product detection, so that the quality control problem of ganciclovir oculentum is solved.

A substance for the treatment of poxvirus including Anacardium occidentale seed extract oil, sunflower oil and an excipient. The Anacardium occidentale seed extract oil and the sunflower oil are mixed and heated together at a predetermined temperature. The excipient is aloe vera or white petrolatum. The substance is topically applied in human skin for relief of poxvirus infection symptoms.

This invention provides a method for preparing and applying a long-acting anthelmintic compound microcapsule. The long-acting anthelmintic compound microcapsule is composed of a component containing an anthelmintic drug, white petrolatum, and pollen microcapsules; the anthelmintic drug content is 10-30 wt% of the total weight. Based on a unique supercritical carbon dioxide mixing process, this invention achieves efficient loading of the anthelmintic agent into the pollen microcapsules under mild conditions. This process further utilizes the porous nature of the microcapsules to achieve sustained release of the anthelmintic agent, thereby effectively prolonging the duration of action. Furthermore, thanks to its micron-sized structure, the microcapsule ensures that the anthelmintic component acts only on the body surface, preventing it from penetrating the skin, thus significantly improving the safety of use.

1. Name of the designed product: packing bottle (S'AXIANU vaseline petrolatum lanolin butter cream). 2. Use of the designed product: packing bottle for containing cosmetics. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo best indicating the design points: front view.

The Formulation describes the preparation of an antimicrobial cream which comprises of humic acid, water and petroleum jelly. The cream acts as a potent antifungal and antibacterial agent and is effective in many skin infections. In clinical trials the cream was found to be effective and well tolerated and free from irritative and allergic reactions.

This invention relates to a peony polyphenol antioxidant face cream, comprising the following ingredients: solution A, solution B, peony polyphenol solution, preservative, and purified water to a final volume of 100 mL; solution A comprises a mixture of glycerol monostearate, cetearyl alcohol, white petrolatum, and isononyl isononanoate; solution B comprises a mixture of 1,3-butanediol, triethanolamine, methyl glucoside sesquistearate, carbomer 940, and glycerin. The formulation of this invention is mild, has good sensory properties, can improve skin photodamage caused by UVB, has anti-photoaging and repair effects, reduces skin thickness changes caused by photodamage, maintains collagen structure, and reduces collagen distortion and breakage; furthermore, the preparation method of this invention is simple and readily available, allowing the efficacy of peony polyphenols to be effectively exerted in this face cream.

The invention discloses a skin wound treatment composition and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine external preparations. The composition is prepared from the following components in parts by weight: 5-25 parts of fresh hibiscus mutabilis, 40-100 parts of fresh hibiscus mutabilis leaves, 2-15 parts of fresh centella asiatica, 1000-3000 parts of white vaseline and 0.1-2 parts of borneol. The preparation method comprises the following steps: cleaning fresh medicinal materials, draining, chopping, adding the chopped medicinal materials into molten albolene, and decocting to fully extract active ingredients; and filtering while hot, adding borneol after the filtrate is cooled, uniformly stirring, and cooling to obtain the ointment. Through scientific compatibility, the effects of clearing away heat and toxic materials, resisting bacteria and diminishing inflammation of the hibiscus mutabilis leaves and the function of promoting tissue repair of the centella asiatica are organically combined, transdermal absorption is enhanced through the borneol, and multi-target synergistic interaction is achieved. The composition has a remarkable curative effect on bedsores, second-degree and lower-degree burns and scalds, surgical incision fat liquefaction and other refractory wounds, the activity of the medicinal materials can be reserved to the maximum extent through the preparation process, and the composition has the advantages of being low in cost and high in application value.

The invention provides amitriptyline hydrochloride emulsifiable paste as well as a preparation method and application thereof, and belongs to the technical field of medicines. The amitriptyline hydrochloride emulsion is prepared from the following components in parts by mass: 3 to 8 parts of amitriptyline hydrochloride, 5 to 10 parts of glycerol, 3 to 8 parts of octadecanol, 3 to 8 parts of hexadecanol, 0.5 to 2 parts of ethylparaben, 2 to 5 parts of white vaseline, 0.5 to 2 parts of lauryl sodium sulfate, 12 to 20 parts of dimeticone, 0.5 to 2 parts of laurocapram, 1 to 5 parts of OP-10 and 40 to 67.5 parts of water. When a neuropathic pain model mouse is smeared with the amitriptyline hydrochloride emulsifiable paste, the symptom of the neuropathic pain of the mouse can be improved, the amitriptyline hydrochloride emulsifiable paste can quickly play a role in easing pain, and repair of injured nerves can be promoted through long-term administration.