27 results about "White petrolatum" patented technology

The invention relates to cream for repairing radiodermatitis and a preparation method of the cream, and belongs to the technical field of biomedical skin treatment. The cream consists of the following components in percentage by weight: 8% of glycerin monostearate, 6% of stearic acid, 5% of white vaseline, 4% of liquid wax, 1-2% of tea tree oil, 1-2% of eugenol, 1-2% of vitamin E, 3% of trehalose, 8% of polyethylene glycol (PEG-400), 10% of glycerol, 0.5% of methylparaben, 1% of triethanolamine and the balance of purified water. According to the cream disclosed by the invention, the natural traditional Chinese medicine component eugenol and the natural substance vitamin E are utilized to synergistically enhance the anti-oxidation and bacteriostatic effects, and the tea tree oil, the trehalose and other effective components are utilized to repair radiodermatitis from multiple aspects of anti-inflammation, bacteriostasis, antioxidation, promotion of skin barrier repair and the like. The cream is simple in component, good in treatment effect, high in safety and convenient to produce and process, and can be popularized and applied to treatment of radiodermatitis.

This application relates to the field of veterinary drug technology, and discloses a transdermal absorption-enhancing ointment and its preparation process. The ointment components include white petrolatum, anhydrous lanolin, caprylic / capric triglycerides, hydrophobic fumed silica, and a highly fluid active permeation-enhancing phase. The permeation-enhancing phase contains active drugs and soybean lecithin, which self-assemble to form an inverse micelle aggregate. Soybean lecithin cross-links with the silanol groups on the surface of silica to form an intermolecular hydrogen bond network, constructing a sterically hindered framework within a continuous lipid matrix to prevent the polar drug-loaded phase from permeating and separating upon heating. Simultaneously, the inverse micelle structure effectively improves the transdermal absorption rate of the drug. The preparation process controls the lipid crystallization kinetics through slow cooling under negative pressure and micro-shear dynamic rheology. This invention solves the problems of easy precipitation upon heating, low transdermal efficiency, and poor rheological properties in traditional ointments, resulting in a product with a stable physical structure and good pseudoplastic texture.

This invention relates to the field of peppermint balm technology, specifically disclosing a peppermint balm with moisturizing and soothing functions and its preparation method, comprising the following raw materials in parts by weight: 40-45 parts white petrolatum, 15-20 parts houttuynia cordata extract doped with nano-silica, 10-15 parts paraffin, 10-15 parts menthol, 5-10 parts trehalose, 2-5 parts hydroxyethyl cellulose, 25-30 parts glycerin, and 2-5 parts Tween-80. The peppermint balm of this invention uses white petrolatum combined with paraffin, and is further blended and formulated with menthol, trehalose, hydroxyethyl cellulose, glycerin, Tween-80, and a modifier. Through the synergistic effect of the attapulgite modifier and the houttuynia cordata extract doped with nano-silica, the prepared peppermint balm achieves a coordinated improvement in moisturizing efficacy, soothing properties for skin redness and swelling from insect bites, and long-lasting antibacterial properties, thus improving the product's efficiency.

The application provides a white-borneol apricot kernel face mask liquid and a preparation method and application thereof, and relates to the technical field of cosmetics. The preparation raw materials of the white-borneol apricot kernel face mask liquid provided by the application include white petrolatum 5-20 parts, mono-diglyceride 1-10 parts, methyl p-hydroxybenzoate 0.01-8 parts, glycerol 1-10 parts, butanediol 0.05-10 parts, Tween-80 0.05-12 parts and compound extraction liquid 10-30 parts in terms of weight percentage. The white-borneol apricot kernel face mask liquid provided by the application has good moisturizing effect, is cold and heat resistant, has good stability and meets the microbial detection standard of cosmetics.

The invention provides a calcipotriol ointment and a preparation method thereof.The ointment preparation is prepared from, by weight, 0.005 part to 0.01 part of calcipotriol, 5 parts to 10 parts of tussilagone, 8 parts to 23 parts of glycerin monostearate, 20 parts to 50 parts of white vaseline, 10 parts to 20 parts of paraffin, 20 parts to 40 parts of liquid paraffin, 15 parts to 45 parts of polyethylene glycol 400 and 8 parts to 12 parts of propylene carbonate.The formula of the calcipotriol ointment is improved; a certain proportion of tussilagone is added into the prescription, and the preparation method is improved, so that the defect that calcipotriol is easy to decompose is overcome, the problem of unstable calcipotriol content is solved, the stability of the calcipotriol ointment is improved, the content of related substances of the calcipotriol ointment is reduced, and the calcipotriol ointment has a synergistic effect in the aspect of treating psoriasis.

The present invention provides a composition to increase tear production to relieve irritation from dry eyes, and a method for application of the composition. The composition includes at least 5% menthol and a carrier. The carrier comprises at least one of: a triglyceride oil, a medium chain triglyceride, petroleum jelly, coconut oil, olive oil, beeswax, a wax that is semi-solid at 21 C, a vegetable wax, an animal wax, a petroleum wax, a mineral wax, a synthetic wax, vaseline, lanoline, hydrogenated rosin / glyceryl diisostearate, hydrogenated polyisobutene, polyethylene, fatty acid cholesteryl, higher fatty acid esters, aliphatic alcohols, squalene, polyethyleneglycol, higher fatty acids, animal oil, and vegetable oil. The method includes delivering the composition to a user's eye.

An eye drop type pharmaceutical composition comprising lipids, white petrolatum, and liquid paraffin, wherein the ophthalmic pharmaceutical composition comprises 3 to 500 milligrams of lipids, 100 to 250 milligrams of white petrolatum, and 1 to 797 milligrams of liquid paraffin per gram.

This invention belongs to the field of pharmaceutical formulation technology and relates to a clobetasol propionate ointment and its preparation process. The ointment comprises clobetasol propionate, an emulsifier, a solubilizer, a stabilizer, a secondary stabilizer, and an ointment base. The emulsifier is Tween-80, the solubilizer is propylene glycol, the stabilizer is povidone K15 or povidone K25, the secondary stabilizer is potassium chloride, and the ointment base is white petrolatum. This invention, by adding a stabilizer and a secondary stabilizer and screening their types, prepares a clobetasol propionate ointment that exhibits low impurity content and good stability during long-term storage. Furthermore, the preparation process is simple and easy to operate, facilitating industrial production.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to a local external cream composition for treating psoriasis. The topical external cream composition for treating psoriasis is prepared from deaminated tyrosine, azone and a matrix, wherein the matrix is prepared from liquid paraffin, sorbitol, an emulsifying agent, tween-80, white vaseline, beewax, glycerin monostearate, solid paraffin and the like according to a specific weight percentage. By optimizing a prescription and a process, the cream composition which is good in stability, high in transdermal absorption efficiency and capable of effectively delivering DAT to a skin focus is prepared, psoriasis-like skin lesion is effectively improved, inflammation and epidermal hyperplasia are relieved, and the cream composition is good in safety. A brand-new, effective and safe external medicine selection and application are provided for the field of psoriasis treatment by taking the deaminated tyrosine as an active component.

The application belongs to the technical field of medicines and the field of ophthalmic preparations, and provides a stable erythromycin ointment composition without preservatives and a preparation method thereof. Through pre-wetting dispersion of erythromycin and liquid paraffin, construction of a white vaseline-liquid paraffin heat-treated oil matrix, low-moisture control, final mixing and redispersion, and nitrogen headspace replacement design, the dispersion state, content uniformity and headspace oxygen level of erythromycin particles are cooperatively controlled, the dispersion stability and chemical stability are improved, the problem that intensive dispersion and stable protection and mild processing and clean production control cannot be considered at the same time is solved, and the stable erythromycin ointment composition without preservatives is suitable for the production of ophthalmic semi-solid preparations without preservatives.

The invention relates to a cosmetic composition in the form of an oil-in-water emulsion free of petroleum jelly and paraffin. This composition comprises water, at least one polyol, 45 to 70% by weight of fatty emollient(s), 8 to 15% by weight of factor(s) having a waxy consistency, and at least one emulsifier selected from sucrose fatty acid esters. This composition proves to be particularly effective for repairing damaged skin by topical application.

The present application belongs to the technical field of external preparations of traditional Chinese medicine, and relates to a cream containing imperatorin and capable of promoting skin wound healing and a preparation method thereof. The cream takes imperatorin and puerarin as core effective components, magnesium lithium silicate and sodium hyaluronate as synergistic repair components, sorbitan oleate and lanolin as emulsifiers, refined sesame oil, squalane and white petrolatum as oil phase matrix, and further includes glycerol, and the rest is deionized water. Animal experiment results show that the cream can promote collagen fiber generation of granulation tissue, promote polarization of repair type macrophages, significantly optimize repair quality and reduce scar formation while improving wound healing rate, and has good safety. The preparation process is stable and controllable, and is suitable for industrial production. The cream can be used for I and II degree mild burn and scald, skin abrasion and other traumatic wounds, and is also suitable for skin problems such as postoperative wound repair of medical beauty and hand and foot chapped skin, has wide clinical application range, and has good application prospect and popularization value.

The invention discloses a chemical detection method for oculent.The chemical detection method relates to the technical field of chemical analysis, the oculentcomprises ganciclovir, yellow vaseline, lanolin, liquid paraffin, white vaseline, glycerin, ethylparaben and vitamin E. The method comprises the following steps that (a) the content of ganciclovir in the oculent.The content of ganciclovir in the oculent.The content of ganciclovir in the oculentis is measured through a high performance liquid chromatography; (b) carrying out quality control on the lanolin raw material, namely measuring an acid value, a saponification value and a peroxide value; (c) carrying out wool fat related quality monitoring on the oculentum finished product, wherein the wool fat related quality monitoring comprises determination of a peroxide value; according to the method, chromatographic conditions are optimized, an exclusive impurity detection method is established, and raw materials are associated with finished product detection, so that the quality control problem of ganciclovir oculentum is solved.

A substance for the treatment of poxvirus including Anacardium occidentale seed extract oil, sunflower oil and an excipient. The Anacardium occidentale seed extract oil and the sunflower oil are mixed and heated together at a predetermined temperature. The excipient is aloe vera or white petrolatum. The substance is topically applied in human skin for relief of poxvirus infection symptoms.

A topical cream composition is provided which comprises a mixture of a moisture barrier component, a steroid component, an antifungal component, and an antibiotic component. The combination of a moisture barrier, a steroid, an antifungal component, and an antibiotic component works together to optimally provide quick treatment and resolution for diaper dermatitis, also known as diaper rash, or other skin condition(s). The moisture barrier component provides a barrier between affected skin and diaper wetness; the steroid reduces swelling, itching, and / or other discomfort; the antifungal component treats any present fungal skin infection(s); and / or the antibiotic component treats any present bacterial skin infection(s). In one aspect, the topical cream comprises a composition of petroleum jelly, hydrocortisone cream, clotrimazole antifungal cream, and triple antibiotic ointment including bacitracin zinc, neomycin sulfate, and polymyxin B sulfate.

The application provides a miconazole nitrate cream and a preparation process, and belongs to the technical field of external medicines, and is characterized in that the miconazole nitrate cream comprises the following components in terms of mass fraction: 1.8wt-2.0wt% miconazole nitrate, 0.3wt-2.0wt% allantoin eugenol amide ester penetration enhancer, 3wt%-5wt% medium-chain triglyceride, 5wt%-10wt% glycerol monostearate, 8wt%-15wt% white petrolatum, 6wt-12wt% glycerol, 0.01wt%-0.10wt% bis(hydroxymethyl)imidazole alkyl urea, 6wt%-12wt% octadecanol, 1wt%-3wt% triethanolamine, and the balance is purified water. The preparation process comprises cream preparation, miconazole nitrate emulsion homogenization and miconazole nitrate cream preparation. The application prepares a nano miconazole nitrate cream product with uniform and delicate texture from the aspects of drug particle size optimization and homogenization. The added allantoin eugenol amide ester penetration enhancer is safe and non-irritating, and the use of the miconazole nitrate cream not only promotes the penetration of the cream and accelerates the recovery of the skin, but also has certain antioxidant function and can effectively prevent the cream from yellowing and deteriorating.

1. The name of the present design product: label (white vaseline). 2. The use of the present design product: label for product packaging. 3. The design points of the present design product: the combination of patterns and colors. 4. The picture or photo that best indicates the design points: design 1 front view. 5. The design for which protection is sought contains colors. 6. The present design product is a planar product, and the back is not often seen during use, so the design 1 left view, design 1 right view, design 1 top view, design 1 bottom view, and design 1 rear view are omitted; the present design product is a planar product, so the design 2 left view, design 2 right view, design 2 top view, design 2 bottom view, and design 2 rear view are omitted; the present design product is a planar product, so the design 3 left view, design 3 right view, design 3 top view, design 3 bottom view, and design 3 rear view are omitted. 7. Design 1 is designated as the basic design.

The invention discloses a body surface non-chronic wound nursing dressing, a preparation method and application, and particularly relates to the technical field of medical dressings, the body surface non-chronic wound nursing dressing is composed of silicon dioxide, calcium carbonate, medical albolene, medical liquid paraffin and medical absorbent gauze or spunlace non-woven fabric. Wherein the silicon dioxide has specific specific surface area and porosity, the calcium carbonate has proper particle size, and the medical albolene and the liquid paraffin keep a specific mass ratio. Through the synergistic effect of all the components, the dressing has the advantages that percolate is efficiently adsorbed, the antibacterial property is good, the wound healing environment is optimized, and the mechanical stability is enhanced. The preparation method comprises the steps of mixing, heating and stirring, coating and shaping and the like. The dressing is suitable for nursing non-chronic body surface wounds such as bruises, incisions and burns, can be replaced once every day during use, does not need to clean the surface of the wound, and can improve the compliance of a patient and promote wound healing.

This invention provides a method for preparing and applying a long-acting anthelmintic compound microcapsule. The long-acting anthelmintic compound microcapsule is composed of a component containing an anthelmintic drug, white petrolatum, and pollen microcapsules; the anthelmintic drug content is 10-30 wt% of the total weight. Based on a unique supercritical carbon dioxide mixing process, this invention achieves efficient loading of the anthelmintic agent into the pollen microcapsules under mild conditions. This process further utilizes the porous nature of the microcapsules to achieve sustained release of the anthelmintic agent, thereby effectively prolonging the duration of action. Furthermore, thanks to its micron-sized structure, the microcapsule ensures that the anthelmintic component acts only on the body surface, preventing it from penetrating the skin, thus significantly improving the safety of use.

The invention provides a medicament for treating skin diseases and a preparation method thereof. The medicament comprises rabdosia rubescens powder, salicylic acid, benzoic acid, procaine, lidocaine and borneol. Preparing powder by combining talcum powder; preparing an ointment by combining with medical albolene; preparing a tincture by combining alcohol and water; the raw materials are low in obtaining cost, skin diseases can be rapidly and effectively treated in a short time, the special effect is achieved especially for fungal diseases, and various preparations can prevent and treat local body surface inflammation, redness, swelling, pain, severe itching and other symptoms caused by local body surface inflammation, redness and swelling of a patient in multiple aspects; the medicament has a remarkable curative effect on acne, psoriasis, eczema, fungal skin infection and mild skin inflammation.

1. Name of the designed product: packing bottle (S'AXIANU vaseline petrolatum lanolin butter cream). 2. Use of the designed product: packing bottle for containing cosmetics. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo best indicating the design points: front view.

The Formulation describes the preparation of an antimicrobial cream which comprises of humic acid, water and petroleum jelly. The cream acts as a potent antifungal and antibacterial agent and is effective in many skin infections. In clinical trials the cream was found to be effective and well tolerated and free from irritative and allergic reactions.

This invention relates to a peony polyphenol antioxidant face cream, comprising the following ingredients: solution A, solution B, peony polyphenol solution, preservative, and purified water to a final volume of 100 mL; solution A comprises a mixture of glycerol monostearate, cetearyl alcohol, white petrolatum, and isononyl isononanoate; solution B comprises a mixture of 1,3-butanediol, triethanolamine, methyl glucoside sesquistearate, carbomer 940, and glycerin. The formulation of this invention is mild, has good sensory properties, can improve skin photodamage caused by UVB, has anti-photoaging and repair effects, reduces skin thickness changes caused by photodamage, maintains collagen structure, and reduces collagen distortion and breakage; furthermore, the preparation method of this invention is simple and readily available, allowing the efficacy of peony polyphenols to be effectively exerted in this face cream.

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to crisaborole ointment as well as a preparation method and application thereof. The crisaborole ointment is prepared from the following raw materials in parts by weight: 0.5 to 1 part of crisaborole, 20 to 25 parts of white vaseline, 1 to 2 parts of paraffin, 2 to 3 parts of glyceryl monostearate and glyceryl distearate, 0.01 to 0.03 part of butylated hydroxytoluene, 2 to 3 parts of propylene glycol and 0.001 to 0.002 part of sodium calcium edetate. The prepared crisaborole ointment is low in melting point, good in stability, uniform in liquid drop, good in viscoelasticity and spreadability, simple in preparation method and suitable for large-scale production.

Compositions and methods for the treatment of pruritic ani and anal fissures are described. The compositions include one or more of Calamine (95% zinc oxide and 0.5% ferric oxide) (USP) or zinc oxide (ZnO), aluminum hydroxide (Al(OH)3) or kaolin, glycerin, and menthol (or any compound which activates the menthol receptor (TRPM8)). The composition does not contain (or contains a limited amount, such as less than 10%) of a hydrocarbon-based pharmaceutical carrier such as petroleum jelly, white petrolatum, mineral oil, hard paraffin, soft paraffin, microcrystalline wax, or ceresine. Methods of treating pruritic ani and anal fissures by topical application(s) of the compositions to affected perianal or anal epidermis are also described.

The invention discloses a skin wound treatment composition and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicine external preparations. The composition is prepared from the following components in parts by weight: 5-25 parts of fresh hibiscus mutabilis, 40-100 parts of fresh hibiscus mutabilis leaves, 2-15 parts of fresh centella asiatica, 1000-3000 parts of white vaseline and 0.1-2 parts of borneol. The preparation method comprises the following steps: cleaning fresh medicinal materials, draining, chopping, adding the chopped medicinal materials into molten albolene, and decocting to fully extract active ingredients; and filtering while hot, adding borneol after the filtrate is cooled, uniformly stirring, and cooling to obtain the ointment. Through scientific compatibility, the effects of clearing away heat and toxic materials, resisting bacteria and diminishing inflammation of the hibiscus mutabilis leaves and the function of promoting tissue repair of the centella asiatica are organically combined, transdermal absorption is enhanced through the borneol, and multi-target synergistic interaction is achieved. The composition has a remarkable curative effect on bedsores, second-degree and lower-degree burns and scalds, surgical incision fat liquefaction and other refractory wounds, the activity of the medicinal materials can be reserved to the maximum extent through the preparation process, and the composition has the advantages of being low in cost and high in application value.

The invention provides amitriptyline hydrochloride emulsifiable paste as well as a preparation method and application thereof, and belongs to the technical field of medicines. The amitriptyline hydrochloride emulsion is prepared from the following components in parts by mass: 3 to 8 parts of amitriptyline hydrochloride, 5 to 10 parts of glycerol, 3 to 8 parts of octadecanol, 3 to 8 parts of hexadecanol, 0.5 to 2 parts of ethylparaben, 2 to 5 parts of white vaseline, 0.5 to 2 parts of lauryl sodium sulfate, 12 to 20 parts of dimeticone, 0.5 to 2 parts of laurocapram, 1 to 5 parts of OP-10 and 40 to 67.5 parts of water. When a neuropathic pain model mouse is smeared with the amitriptyline hydrochloride emulsifiable paste, the symptom of the neuropathic pain of the mouse can be improved, the amitriptyline hydrochloride emulsifiable paste can quickly play a role in easing pain, and repair of injured nerves can be promoted through long-term administration.